Eisai Environmental Report 2016
Ongoing Efforts to Ensure Coexistence with the Global Environment
The Eisai Group conducts business operations emphasizing protection of the global environment based on the Eisai Network Companies (ENW)
Environmental Protection Policy. By quantitatively assessing resource input and environmental impact, we strive to reduce our burden on the
environment and promote environmental protection activities worldwide.
Reduction of Environmental Impact
The Eisai Group conducts business operations seeking coexistence with the global environment. Based
on the Eisai Network Companies (ENW) Environmental Protection Policy, all employees recognize the
importance of environmental protection and incorporate an environmental perspective in working to
execute our social responsibilities.
Today, we face many global environmental issues, such as climate change and water shortages,
which have substantial impact on a sustainable society. There are also significant issues concerning
environmental protection, including air pollution, waste problems and destruction of the natural
environment. In addition to observing environmental laws and regulations, ordinances and agreements
with local governments, the Eisai Group implements more stringent voluntary standards and undertakes
activities accordingly in order to ensure coexistence with the global environment through its business
operations. In promoting business expansion into countries across the world, we will fulfill our corporate
social responsibility by focusing on reducing environmental impact at each stage of business.
Eisai Network Companies (ENW) Environmental Protection Policy
Fundamental Environmental Protection Policy
Eisai and its Group companies (hereafter ENW) place global environmental protection as an important component of business
operations and strive to maintain the environment.
Environmental Protection Guidelines
1. ENW is aware of the “dignity and importance of nature” and adopts measures to maintain the global environment in all
business operations.
2. ENW places environmental protection as a top priority at all stages of corporate activities from research and development,
production, distribution and sales to product usage and disposal.
3. ENW constructs and operates an environmental management system and promotes environmentally protective operations.
4. ENW complies with all applicable laws, regulations and agreements concerning environmental protection, and each company
implements voluntary standards that exceed the minimum standards set forth in the applicable laws, regulations and
agreements.
5. ENW actively introduces advanced environmental technology to be at the forefront of reducing environmental impacts.
6. ENW reduces usage of resources and energy as well as reduces or recycles waste products in all business operations.
7. ENW reduces usage and promotes the removal of chemical substances that cause environmental pollutant emission and
prevents environmental pollution.
8. ENW shares the fundamental policy on environmental protection and implements educational training to strengthen specialties
at each workplace progressively and continuously.
9. ENW actively discloses information on policies, objectives, programs and results concerning environmental protection.
1
Manufacturing and Drug Discovery Research Sites Worldwide
●European Knowledge Centre (United Kingdom)
Benxi Plant (China)●
Suzhou Plant (China)●
●Kawashima Plant (Gifu)
●Kashima Plant (Ibaraki)
●Tsukuba Research Laboratories (Ibaraki)
●KAN Research Institute (Hyogo)
Andover Research Institute (United States)
●
●H3 Biomedicine Inc. (United States)
●
Morphotek Inc. (United States)● ● Baltimore Plant (United States)
North Carolina Plant (United States)
●
Eisai Knowledge Centre,
India (India)
●Bogor Plant (Indonesia)
Editorial Policy
Period Covered
This report describes Eisai’s approach toward environmental protection and provides details of environmental activities
undertaken during fiscal 2015. The report has been developed in reference to the Environmental Reporting Guidelines (2012
Version) issued by Japan’s Ministry of the Environment and includes Eisai’s efforts both in and outside Japan.
The data has been aggregated based on the results achieved from April 1, 2015 to March 31, 2016.
Scope of Reporting
For inquiries regarding this report, please contact:
Eisai Co., Ltd.
General Affairs and Environmental & Safety Affairs Department
Tel: +81-3-3817-5358
Fax: +81-3-3811-9982
The scope of data aggregation in this report primarily covers Eisai Co., Ltd. and its Group companies in Japan as well as its
production sites and research centers outside Japan. The scope of individual data is specified as needed.
Inquiries
2
Glossary and CO2 Emissions Coefficient
Energy Consumption and CO2 Emissions Coefficient Used in Emissions Calculations
Glossary
Term
ISO 14001
Description
An international standard for environmental management issued by the International Organization
for Standardization
EA21
EcoAction 21: an environmental management system certification for small- and medium-sized
enterprises issued by Japan’s Ministry of the Environment
PRTR
Pollutant Release and Transfer Register: A system for understanding, collecting and publicly
disclosing information on the extent to which chemical substances involving environmental risk
are either released into the environment or are contained in waste matter and transferred from
operational sites
SOx
Sulfur oxides
NOx
Nitrogen oxides
BOD
Biochemical oxygen demand: A measure used to evaluate the quality of river water and factory
wastewater
Scope 1
Energy-derived direct greenhouse gas (GHG) emissions. GHG emissions released directly into the
atmosphere through the use of fuels
Scope 2
Energy-derived indirect GHG emissions. GHG emissions associated with the use of purchased
energy (electricity and heat)
Scope 3
Other indirect GHG emissions. GHG emissions associated with business activities in a supply chain,
other than Scope 1 and Scope 2 emissions
VOCs
Volatile organic compounds: Organic compounds that are volatile at ordinary temperatures and
cause air pollution through the generation of photochemical oxidants
Zero emissions
The Eisai Group uses this term as a target of emission management. It indicates a ratio of waste
sent to landfill to total waste of less than 1.0%.
Energy type
Calorific value per unit
FY2015
CO2 emissions coefficient
In and before FY2012
In and after FY2013
＊1
Electric power
9.97 (GJ/MWh)
LPG
50.1 (GJ/tons)
3.00 (tons/tons)
3.01 (tons/tons)
LNG
55.0 (GJ/tons)
2.70 (tons/tons)
2.76 (tons/tons)
Natural gas
40.2 (GJ/1,000 Nm3)
2.22 (tons/1,000 Nm3)
2.06 (tons/1,000 Nm3)
Processed natural gas
40.1 (GJ/1,000 Nm3)
2.23 (tons/1,000 Nm3)
2.03 (tons/1,000 Nm3)
Kerosene
36.5 (GJ/kl)
2.49 (tons/kl)
2.50 (tons/kl)
Light oil
38.1 (GJ/kl)
2.59 (tons/kl)
2.62 (tons/kl)
Fuel oil A
38.9 (GJ/kl)
2.71 (tons/kl)
2.76 (tons/kl)
Gasoline
33.1 (GJ/kl)
2.32 (tons/kl)
2.28 (tons/kl)
Industrial steam
1.02 (GJ/GJ)
＊2
Hot water and cold
water
1.36 (GJ/GJ)
0.057 (tons/GJ)
＊1 E
missions in Japan are calculated using the emissions coefficient announced by the Federation of Electric Power Companies of Japan (FEPC).
The coefficient for fiscal 2015 has not yet been finalized, and calculations for fiscal 2015 use the emissions coefficient for fiscal 2014. In
calculating emissions outside Japan, the emissions coefficient is taken from the following source. However, the coefficient for fiscal 2013 is
used to calculate emissions for fiscal 2014 and 2015, since corresponding figures are not available from the source.
IEA: CO2 EMISSIONS FROM FUEL COMBUSTION (2015)
＊2 C
alculations use the emissions coefficient provided by respective suppliers every fiscal year.
3
1
Environmental Protection Initiatives and Results
Fiscal 2015 Environmental Protection Initiatives and Results of the Eisai Group in Japan
Theme
Enhancement
of
environmental
management
Energy
conservation
and combating
climate change
Targets
Results
Evaluation Pages
Enhancement and smooth operation of
management systems
• Proper application of the PDCA cycle
• Periodic and renewal inspection of ISO 14001 certification
(Kawashima Plant, Kashima Plant, Sannova Co., Ltd., EIDIA
Co., Ltd. Ibaraki Plant)
• Interim and renewal inspections of EA21 certification
(Sunplanet Co., Ltd., Eisai Distribution Co., Ltd.)
○
P7
Planning and implementation of environmental
education
Internal training sessions: 32; external training sessions: 8
○
P7
Implementation of environmental communication
• Publication of the Environmental Report 2015
• Local community meetings (Kawashima Plant) and
administrative committee meetings (Kashima Plant)
○
P8
Reduction of CO2 emissions by 23% from fiscal
2005 level by fiscal 2020.
CO2 emissions: 73,446 tons＊1
(3.3% decrease from fiscal 2014)
60,710 tons＊2
(33.7% decrease from fiscal 2005)
○
Promotion of the replacement of commercial
vehicles with hybrid vehicles (Eisai Co., Ltd.)
Adoption rate for commercial vehicles: 64%
(9% increase from fiscal 2014)
(Adoption rate for company-owned vehicles: 80%
Adoption rate for employee- owned vehicles: 53%)
○
P10
Proper management of fluorocarbons
Implement legally required inspections based on the Act
on Rational Use and Proper Management of Fluorocarbons
and systematically change to hydrofluorocarbons and nonfluorocarbons
○
P14
Purchase of wind-generated green power
Purchase of 1,000,000 kWh from Japan Natural Energy Co.,
Ltd.
○
—
• Reduction of waste generated
• Increase in recycled waste
• Reduction of waste sent to landfill
• Amount of waste generated: 3,481 tons
(decrease of 617 tons from fiscal 2014)
• Amount of recycled waste: 1,011 tons
(decrease of 93 tons from fiscal 2014)
• Amount of waste sent to landfill: 10 tons
(decrease of 22 tons from fiscal 2014)
○
P12
Ratio of waste sent to landfill to total waste < 1%
• Eisai Co., Ltd.: 0.12%
• Eisai Group companies in Japan: 0.77%
• Eisai Group in Japan: 0.23%
○
P12
Implementation of onsite inspections based on
the Waste Management and Public Cleansing
Law
Implemented onsite inspections based on the Waste
Management and Public Cleansing Law at more than 39 sites
nationwide; confirmed that waste is being disposed of legally
and in a proper manner
○
P12
Waste reduction
Theme
Targets
Results
Evaluation Pages
Resource
conservation
Promotion of awareness-raising activities and
education to encourage green purchasing
Awareness-raising activities and education were provided on
a timely basis. The green purchasing rate: 31.3%.
○
P14
Management
of chemical
substances
Response to PRTR system and proper
management of designated substances
Proper management based on an understanding of amounts
of substances subject to the PRTR system that were handled,
emitted and transferred
○
P13
Air pollution
and water
pollution
prevention
measures
Compliance with Air Pollution Control Act,
Water Pollution Control Act and pollution control
agreements
Regular measurements showed that the amounts of pollutant
emissions into the atmosphere and water systems were below
standard values
○
P8, 15
○
P8
Compliance with environment-related laws (noise, Regularly measured levels of noise, vibrations and offensive
vibrations, offensive odors, soil contamination)
odors to confirm compliance
P9
Involvement with local community
Held regular cleanup activities of areas around each operation
site and affiliated company as well as within industrial parks
○
—
Zero complaints made by neighboring residents
Kawashima Plant received a complaint from neighboring
residents about noise.
The noise resulted from the activation of a safety valve caused
by a malfunction of a pressure-reducing valve at the tip of a
steam pipe and a subsequent increase of pressure inside the
pipe to a level above standard values. The pressure-reducing
valve was quickly replaced and the situation was improved.
×
—
Conservation
of the local
environment
＊1 T
he carbon emissions coefficient based on power usage utilized was 0.554 t-CO2/MWh, the same coefficient used in fiscal 2014.
＊2 The carbon emissions coefficient based on power usage utilized was 0.421 t-CO2/MWh, which is used in evaluating targets of the Eisai Group
in Japan. For details, please refer to page 44 of the Environmental and Social Report 2014.
4
2
Resource Input and Environmental Impact
Resource Input and Environmental Impact
Environmental Impact
OUTPUT
Resource Input and Environmental Impact Data of the Eisai Group in Japan
Atmospheric Emissions (from operational sites)
Resource Input
Eisai Co., Ltd.
INPUT
Eisai Co., Ltd.
Electric power (MWh)
LPG (tons)
Processed natural gas (1,000 Nm3)
Group companies
in Japan
77,603
22,204
99,807
48
9
57
6,215
1,547
7,762
Kerosene (kl)
0
72
72
Light oil (kl)
1
0
1
Fuel oil A (kl)
56
6
61
Gasoline (kl)
2,081
210
2,291
Industrial steam (GJ)
40,181
0
40,181
Hot water (GJ)
0
0
0
Cold water (GJ)
12
0
12
Water consumption (1,000m3)
Clean water (1,000m3)
Industrial water (1,000m3)
Groundwater (1,000m3)
Desalinated water (1,000m3)
Recycled water (1,000m3)
Total
2,978
95
3,073
154
89
243
2
1
3
2,752
2
2,754
6
0
6
64
3
67
Eisai Co., Ltd.
(10,000 sheets)
15,665
73,446
0.6
0.0
0.6
NOx (tons)
5.8
1.6
7.3
Soot and dust (tons)
0.3
0.0
0.3
2,294
PRTR substances
(release into the atmosphere) (tons)
Group companies
in Japan
664
Amount recycled (tons)
2,958
Amount sent to landfill (tons)
PRTR substances
Total amount handled
(including unreported amount)
(tons)
474
Wastewater discharge
2
Total
476
CO2 emissions from
business-use vehicles other
than commercial vehicles (tons)
(1,000m3)
BOD (tons)
3,481
778
233
1,011
3
7
10
Transportation and delivery
(upstream) (tons)
85
2
86
Waste generated
in operations (tons)
2,473
78
2,551
480
5,208
16
11
27
Eisai Co., Ltd.
Group companies
in Japan
Total
204,544
77,623
282,167
10,327
2,881
13,208
3,307
786
4,093
802
125
927
3,180
494
3,674
Business travel (tons)
463
220
683
7.6
Employee commuting
(tons)
442
1,542
1,983
Transportation and delivery
(downstream) (tons)
2,584
454
3,038
371
225
597
Nitrogen (tons)
2.8
0.2
3.0
1) Due to rounding, the sum of “Eisai Co., Ltd.” and “Group companies in Japan” may not correspond to “Total” for some items.
Phosphorous (tons)
0.1
0.0
0.1
2) The transportation and delivery of Eisai products manufactured in Japan is managed by Eisai Distribution Co., Ltd., which is primarily
responsible for logistics management and management of distribution facilities, with actual transportation and delivery being conducted by
external operators. Vehicles belonging to Eisai Distribution Co., Ltd. are used for internal purposes only and are never used for delivery.
PRTR substances
0.0
0.0
0.0
(release into water bodies) (tons)
Fuel- and energy related
activities not included
in Scope 1 or 2 (tons)
878
0.1
Total
4,728
Total
2,603
7.5
Group companies
in Japan
＊
Capital goods (tons)
Group companies
in Japan
Eisai Co., Ltd.
Indirect CO2 Emissions (Scope 3 )
37.3
Total
PRTR substances
Group companies
in Japan
0.0
Waste
Eisai Co., Ltd.
(off-site transfer as waste) (tons)
Eisai Co., Ltd.
37.3
CO2 emissions from
commercial vehicles (tons)
Purchased goods and
services (tons)
Amount generated (tons)
Other
Copy paper consumption
57,782
SOx
Group companies
in Japan
Eisai Co., Ltd.
Total
Exhaust Gas from Vehicles
Total
(tons)
CO2 (Scope 1, 2) (tons)
Water
Energy
Group companies
in Japan
End of life treatment of
sold products (tons)
Containers and Packaging Recycling
Recycling of containers
and packaging materials
Eisai Co., Ltd.
Group companies
in Japan
Total
2,887
76
2,963
(oblitory recycling amount) (tons)
＊ Calculations based on the Basic Guidelines on Accounting for Greenhouse Gas Emissions Throughout the Supply Chain, Version 2.1
(released by the Ministry of the Environment and the Ministry of Economy, Trade and Industry)
5
3
Environmental Accounting
The Eisai Group in Japan has used a standardized form for assessing environmental costs to tabulate any discernible investments and expenses
relating to environmental protection and has been effectively promoting environmental protection activities. We will seek to identify the economic
effects of environmental protection measures and make improvements to increase the form’s usefulness as a management index.
Environmental Protection Costs in Fiscal 2015 (In “major implementation items,” ○ indicates investment and △ indicates expense.)
Main category
Subcategory
Major implementation items
1. Environmental management systems △ ISO 14001 regular and recertification inspections
0
Pages
3
• Promotion of environmental protection activities
P7
• Reduced CO2 emissions from commercial
vehicles by 462 tons (down 9% year on year)
• Purchased 1,000,000 kWh of wind-generated
green power (reduced CO2 emissions by
496 tons)
P9-10
28
15
3. Resource conservation activities
○ Renewal of recycled water supply facilities
△ Maintenance of wastewater treatment system
△ Green purchasing
33
1,315
4. Air pollution prevention measures
△B
oiler repair and inspection
△ Atmospheric analysis
△ Disposal of fluorocarbons
0
5. Management of chemical substances ○ Database usage expenses
0
△ Entrustment of waste disposal
6. Waste reduction activities
0
7. Product design
0
△ Management of waste treatment facilities＊
○ Disposal of polychlorinated biphenyl (PCB) waste
1. Waste disposal
0
(million yen)
Major results / outcomes
Renewal of air conditioners
Partitioning of air-conditioning areas
Introduction of LED lighting
Relocation, maintenance and management of energy
monitoring equipment
△ Introduction of hybrid cars for commercial vehicles
△ Purchase of green power
2. Energy conservation and measures
to address climate change
A. C
osts to achieve
objectives
○
○
○
△
○ Investment △ Expense
Eco-Efficiency
7
0
• Recycled water: 64,000 m3
• Promotion of purchasing environmentally
friendly products
P14
• Prevention of air pollution
P8
• Appropriate management of chemicals
Eco-Efficiency
—
• Amount of waste generated decreased by
617 tons
• Recycled amount decreased by 93 tons
• Amount sent to landfill decreased by 22 tons
P12
0
—
70
• Compliance with related laws and regulations
P13
120
○ Renewal of TOC analyzers and sampling pumps for
B. Costs to comply
with environmental
regulations
wastewater
2. Pollution prevention measures
○W
astewater treatment facilities management expenses
△ Cleaning of various drainage tanks
△W
astewater, noise, vibration and odor measurements
3
185
3. Soil contamination
△ Inspection costs for fuel oil A leakage
0
4. Recycling of containers and
packaging
△ Subcontracting of container and packaging recycling
C. Environmental
1. Environment-related costs excluding △ Greenery maintenance and management costs
A and B
△ Publication of the Environmental Report 2015
administration costs
Total
0
• Prevention of contaminant discharge
P8
0
• Prevention of soil and groundwater
contamination
P8
27
• Compliance with the Containers and Packaging
Recycling Act
P5
• Promotion of business activities that coexist
with nature
• Improved communication
—
0
82
64
1,834
＊ Includes depreciation costs
For the Eisai Group in Japan, we calculated eco-efficiency indicators
using various environmental impact categories, such as CO2
emissions, amount of waste generated, amount of PRTR designated
substances handled, water consumption, biological oxygen demand
(BOD) and sulfur oxides (SOx) and nitrogen oxides (NOx) emissions.
For each fiscal year under evaluation, eco-efficiency was calculated
by dividing environmental impact by net domestic sales volume.
The table below shows a comparison of the resulting figures, using
fiscal 2008 as the base year. Declines mean improved environmental
performance. The trend for some primary indicators is also shown in
the graph below.
Indicator
FY2008 FY2009 FY2010 FY2011 FY2012 FY2013 FY2014 FY2015
CO2 emissions
100
91
91
97
111
115
102
102
Waste generation
100
76
72
76
74
55
52
47
PRTR substances
100
64
88
112
81
66
80
79
Water consumption
100
95
77
92
99
102
102
112
SOx
100
112
87
85
73
54
59
28
NOx
100
88
86
59
64
54
62
46
BOD
100
87
84
50
64
68
82
81
Eco-efficiency
100
84
83
86
83
75
77
72
Primary Indicators
CO2
Waste
Water
PRTR
Eco-efficiency
120
100
80
Economic Effect of Environmental Protection Measures
(million yen)
Item
Details
Sales of by-products
Proceeds from selling recyclable items
12
Reduction in synthetic solvent expenses through recycling
Reduction in synthetic solvent expenses through distillation of waste solvent in the production process
19
Total
Scope of calculations: Eisai Group in Japan
Period of data collection: April 1, 2015 through March 31, 2016
Notes:1) Figures are rounded to the nearest hundred thousand yen.
2) Since fiscal 2004, personnel costs have included only the subcontractors’ commissions.
60
Amount
31
40
20
0
2008
2009
2010
2011
2012
2013
2014
2015 (Fiscal year)
6
4
Environmental Management
Promotion Structure
Environmental Education
The Eisai Group established the CompanyWide Environment and Safety Committee as a
decision-making body for deliberation of important
environmental issues.
To the present, the committee mainly carried
out discussions focused on Japan. However,
the committee is now promoting global activities
encompassing topics from overseas.
As a consultative body promoting the
environmental activities of Group companies
in Japan, the Eisai Group also established the
Environment and Safety Conference of Group
Companies in Japan to share information and
discuss relevant activities.
In accordance with the revision of Japan’s
Companies Act in fiscal 2015, Eisai is strengthening
activities for ascertaining environment-related risks
and is establishing measures to reduce them.
Each operational site of the Eisai Group has
established its own unique management system
to promote environmental activities. Eisai’s main
production sites in Japan as well as the Suzhou Plant
in China and Vizag Plant in India have all acquired
ISO 14001 certification and are conducting activities
based on the standard while striving to raise
awareness through environmental education and
environmental risk management training. Besides
complying with environmental laws, ordinances
and agreements, we periodically conduct internal
environmental audits by a department specializing in
internal auditing to identify and solve issues.
Structure to Promote Environmental Management
Corporate Officer Responsible
for General Affairs,
Environmental & Safety Affairs
Company-Wide
Environment
and Safety Committee
Eisai Co., Ltd.
Operational sites / Headquarters office complex＊
Communication offices
Group Companies outside Japan
Environment-related meetings
Specific Projects
•Energy Conservation Study Meeting
•Waste Processing Study Meeting
General Affairs and
Environmental & Safety
Affairs Department
Environment and Safety
Conference of Group
Companies in Japan
Group Companies in Japan
Environment-related meetings
In order to promote environmental protection
activities ensuring coexistence with the global
environment, it is important that all employees
have a proper understanding of the relationship
between their daily work and environmental
problems, and that they make efforts to enhance
their own individual awareness for problemsolving. At the Eisai Group, operational sites and
Group companies voluntarily formulate education
programs in accordance with their respective
business characteristics and local issues. In addition
to education targeted at all workers, education
is also provided for various levels of employees,
along with further efforts to improve the learning
content. Furthermore, for the purpose of developing
environmental educators and officially qualified
employees and improving the level of environmental
awareness of individual employees, we also actively
promote participation in both internal and external
professional training courses.
Internal Audits
The Eisai Group has environmental internal audits
conducted by a department specializing in internal
auditing. This department makes efforts to undertake
objective audits from an independent standpoint,
and the audits cover all Group companies in and
outside Japan. Audit results for fiscal 2015 indicated
that there were no urgent or serious issues.
External inspections are also carried out once a
year at those operational sites and Group companies
that have acquired ISO 14001 certification
to confirm the validity of their environmental
management systems. During fiscal 2015, no
serious material issues were identified by external
auditing organizations. Furthermore, these certified
operational sites and companies also educate their
own internal auditors and seek to raise the level of
their audits through training. The results of each
annual independent internal audit are reflected in the
ongoing improvement of the Group’s environmental
management system and translate into the
enhanced quality of our environmental protection
activities.
＊ The Eisai Co., Ltd. office complex that serves as the corporate headquarters for the Eisai Group
Operational Sites Certified under ISO 14001
●Eisai Co., Ltd., Kawashima Plant and Kashima Plant●Sannova Co., Ltd.＊1
●Eisai China Inc., Suzhou Plant
●EIDIA Co., Ltd.＊2, Ibaraki Plant
●Eisai Pharmaceuticals India Pvt. Ltd., Vizag Plant
＊1 Eisai Co., Ltd. transferred business operations of Sannova Co., Ltd. to another company on April 1, 2016.
＊2 Eisai Co., Ltd. transferred business operations of EIDIA Co., Ltd. to another company on December 28, 2015.
7
Environmental Risk Management
The Eisai Group in Japan has compiled its
procedures for responding to environmental
incidents in its Disaster and Accident Response
Manual and the Industrial Accident Reporting
and Compilation Standards. We aim to minimize
damage by collecting accurate information and
taking swift and appropriate action and at the
same time make every possible effort to prevent
recurrence. At production plants and research
facilities, in particular, we have been preparing for
an emergency by regularly conducting emergency
Environmental Communication
drills assuming, for instance, the leak of hazardous
chemical substances from wastewater, exhaust gas
or effluents as situations that significantly affect the
environment.
Along with these efforts,
we issued our own independent guidelines, working
to identify sources of risks, and
enhancing our risk management structure with a
view to further ensuring appropriate environmental
risk management Groupwide, including Group
companies outside Japan.
Compliance with Laws and Regulations
The Eisai Group in Japan is committed to observing
environmental laws and regulations, ordinances and
agreements with local governments. In particular,
at production plants and research facilities, we
regularly measure the environmental burden of
causative agents in air pollution and water pollution
to check that there are no problems. Also, from
the perspective of protecting the neighboring
environment, we conducted regular measurements
of noise, vibrations and offensive odors at production
plants and research facilities and confirmed that
these all were below the regulatory values.
In promoting our business activities, mutual
understanding and cooperation with the local
community is extremely important. As such, the
Kawashima Plant has been holding local community
meetings every year since 2008 as a platform for
sharing information and enhancing communication
with the local community. The plant invites
neighborhood representatives and government
officials to these meetings to introduce its production
activities and environmental protection initiatives and
also listen directly to participants’ comments and
requests to the plant.
Environmental Incident Report
During fiscal 2015, we made steady progress in
our response to the Act on Rational Use and Proper
Management of Fluorocarbons that went into effect
in April 1, 2015.
We also submitted each type of environmental
notification to the relevant authorities without any
delay. There were no administrative dispositions or
lawsuits related to the environment.
Environmental Incidents and Countermeasures in Fiscal 2015
Environmental incident
Operational site/company
Details
Response
Leakage
Kawashima Plant
Fluorocarbon refrigerants
leaked from an air-cooled
chiller installed on the
roof of the No. 4 Drug
Formulation Building
Leakage
Tsukuba Research Laboratories
Fluorocarbon refrigerants
leaked from a chiller unit
adjacent to the machinery
building
An incident report was filed with the Southern Region Residents’
Center, Environmental and Industrial Safety Division, Ibaraki
Prefecture. We identified the leakage area and replaced the
relevant part.
Leakage
Sannova Co., Ltd.
Fluorocarbon refrigerants
leaked from air conditioner
refrigerant piping in the
North Drug Formulation
Building machinery room
An incident report was filed with the Environmental Conservation
Section, Environment and Forestry Department, Gunma
Prefecture. We identified the leakage area and replaced the
relevant part.
Leakage
Sannova Co., Ltd.
Fluorocarbon refrigerants
leaked from an air
conditioner compressor
at the Research Quality
Management building
We identified the leakage area and replaced the relevant part.
An incident report was filed with the Fire Department of
Kakamigahara City. We are progressing with plans for repairing
the malfunctioning chiller after identifying the cause of the
leakage.
8
5
Formation of a Low-Carbon Society
Toward the Formation of a Low-Carbon Society
The Eisai Group in Japan is promoting initiatives for
the formation of a low-carbon society to help solve
the problem of climate change. Eisai Co., Ltd. is
participating in the Commitment to a Low Carbon
Society initiated by the Federation of Pharmaceutical
Manufacturers’ Associations of Japan (FPMAJ), and
the Eisai Group in Japan is implementing relevant
initiatives based on its own medium-term plan for
the reduction of CO2 emissions.
During fiscal 2015, we transferred Group
companies EIDIA Co., Ltd. and Eisai Food &
Chemical Co., Ltd. as well as the North Carolina
Plant in the U.S. to other companies. Therefore, the
scope of emissions changed significantly and CO2
emissions decreased both in and outside Japan.
We also progressed with the consolidation of our
domestic sales bases and this led to a reduction in
the amount of energy consumption.
As energy-saving initiatives, we reduced the air
conditioner running times at the Tsukuba Research
Laboratories and renovated each type of boiler at the
Kawashima Plant. Overseas as well, we promoted
energy-savings for air conditioning equipment
at Andover Research Institute and implemented
initiatives for reducing the amount of natural gas
consumption at Morphotek Inc. On the other hand,
increases in the amount of energy consumption
were caused by the expansion of the Suzhou Plant
in China and the activation of research activities of
H3 Biomedicine Inc. As a result, the Eisai Group’s
CO2 emissions for the Eisai Group in Japan and
production plants and research facilities outside
Japan showed a 3.3% and 11.6% decrease,
respectively, from fiscal 2014.
Eisai Group in Japan CO2 Emissions＊1, ＊2
Eisai Co., Ltd.
Group companies in Japan
120,000
100,530
91,742
91,558
81,096
80,000
Eisai Group in Japan
(CO2/t)
180,000
160,000
140,000
120,000
146,433
123,099
155,658
161,918
Overseas operational sites
164,031
139,596
131,263
123,443
100,000
80,000
60,000
40,000
20,000
0
2008
2009
2010
2011
2012
2013
2014
2015
(Fiscal year)
CO2 Emissions by Region＊2, ＊3
(t)
100,000
Eisai Group CO2 Emissions＊2, ＊3
79,410
92,641
(tons)
Region
Scope 1
Scope 2
Total
Japan
16,280
57,166
73,446
Asia
2,666
17,050
19,716
U.S.
9,094
16,819
25,913
Europe
1,658
2,711
4,369
82,026
75,942
73,446
60,000
＊2 E
missions from vehicles are not included.
＊3 E
missions from business activities at offices outside Japan are not included.
40,000
20,000
0
2005
2008
2009
2010
2011
2012
2013
2014
2015
(Fiscal year)
＊1 Revisions were made to the fiscal 2014 data provided in the previous year’s report by using the finalized
coefficient shown below.
FY2014 carbon emissions coefficient based on power usage = 0.554 t- CO2/MWh
9
Efforts Undertaken at Offices
In accordance with the “Seven Power-Saving
Rules,” the Eisai Group in Japan strives to save
electricity throughout the year, not only during
the power-saving campaigns held in summer and
winter. Offices, including administration and sales
offices, concentrate on power-saving efforts, such
as controlling the temperature of air-conditioning
systems, turning off lights when not in use and
shutting down computers when employees leave
their seats for a while. At large buildings, we
install demand controllers to control peak power.
We also focus on raising employee awareness of
reducing power by implementing regular energysaving patrols and visualizing actual power savings
achieved. CO2 emissions originating from business
activities at offices of the Eisai Group in Japan in
fiscal 2015 totaled 3,720 tons, a 10.1% decrease
from fiscal 2014.
Efforts concerning Commercial Vehicles
Office Activitiess CO2 Emissions (Eisai Group in Japan)
（t）
5,000
4,000
4,547
3,774
3,999
Eisai Co., Ltd. also undertakes efforts to reduce
CO2 emissions from sales operations. In Japan,
the replacement of commercial vehicles with
hybrid vehicles has been proceeding, whereby as
a general rule, we have required to choose hybrid
vehicles when purchasing new vehicles since 2010.
4,139
4,025
3,719
Commercial Vehicles CO2 Emissions
3,000
（CO2/t）
7,000
2,000
CO2 emissions
6,346
6,000
1,000
0
Consequently, the adoption rate reached as high as
64% in fiscal 2015, and CO2 emissions originating
from commercial vehicles decreased 8.9% from
fiscal 2014 to 4,728 tons. We will continue shifting
to more fuel-efficient vehicles as part of our efforts to
further reduce emissions.
Hybrid vehicle adoption rate
64
6,067
5,654
2011
2012
2013
2014
70
60
55
5,190
5,000
2010
（%）
4,728
50
49
2015
(Fiscal year)
4,000
3,000
40
42
30
33
2,000
20
1,000
10
0
2011
2012
2013
2014
2015 (Fiscal year)
0
CO2 Emissions Breakdown by Scope (Scopes 1 and 2, Eisai Group in Japan)
(tons)
Scope 1
Scope 2
15,933
50,933
66,866
Offices
186
3,534
3,720
Ware house
Production plants and research
facilities
Total
161
2,699
2,860
Vehicles for commercial and other
business use
5,235
0
5,235
Total
21,515
57,166
78,681
10
Breakdown of Energy Consumption
Electric power
(MWh)
Amount used
In Japan Calorific value (GJ)
Ratio (%)
Amount used
Outside
Japan
Calorific value (GJ)
Ratio (%)
Amount used
Total
Calorific value (GJ)
Ratio (%)
LPG
(tons)
LNG
(m3)
Natural gas
(1,000 m3)
Processed natural
gas (1,000 m3)
72
1
61
2,291
40,181
12
995,075.79
2,855.7
0
0
311,256.2
2,628
38.1
2,372.9
75,832.1
40,984.62
16.32
69.5
0.2
0.0
0.0
21.8
0.2
0.0
0.2
5.3
2.9
0.0
62,120
5
497
5,192
0
0
498
7
0.3
10,237
0
619,336.4
250.5
27,335
208,718.4
0
0
18,973.8
272.3
9.93
10,442
0
70.0
0.0
3.1
23.6
0.0
0.0
2.1
0.0
0.0
1.2
0.0
161,927
62
497
5,192
7,762
72
499
68
2,291.3
50,418
12
1,614,412.1
3,106.2
27,335
208,718.4
311,256.2
2,628
19,011.9
2,645.2
75,842.03
51,426.36
16.32
69.7
0.1
1.2
9.0
13.4
0.1
0.8
0.1
3.3
2.2
0.0
(tons)
2012
2013
2014
897
601
614
590
570
8,964
8,811
8,670
173
163
166
Bracco-Eisai Co., Ltd.
99
110
123
109
110
1,810
2,053
2,633
2,699
2,861
KAN Research Institute, Inc.
557
575
626
2,687
2,591
EIDIA Co., Ltd.
752
736
946
852
645
64
66
74
69
53
400
309
123
0
0
12,683
12,793
14,276
15,979
15,665
Eisai Group in Japan Total
＊1 The Eisai Food & Chemical Co., Ltd. was transferred to another company and was accordingly excluded from the Group as of February 1, 2016.
(tons)
2011
2012
2013
2014
2015
26,371
26,386
29,141
26,999
26,391
20,247
20,288
20,597
0
0
960
1,063
1,223
1,124
1,060
7,912
7,840
8,701
8,142
8,297
20,050
20,659
22,466
20,071
18,754
Headquarters office complex
1,880
1,914
2,150
2,008
1,912
Communication offices
(sales offices in Japan)
1,638
1,699
1,977
1,618
1,367
Eisai Co., Ltd. Total
79,059
79,847
86,254
59,963
57,782
Eisai Group in Japan Total
91,742
92,641
100,530
75,942
73,446
Office name
129
Others
Eisai Co., Ltd. CO2 Emissions
2015
8,214
＊1
Cold water
(GJ)
7,762
133
Eisai Food & Chemical Co., Ltd.
Industrial steam
(GJ)
0
7,972
Eisai Distribution Co., Ltd.
Gasoline
(kl)
0
Elmed Eisai Co., Ltd.
Sannova Co., Ltd.
Fuel oil A
(kl)
57
2011
Sunplanet Co., Ltd.
Light oil
(kl)
99,807
Group Companies in Japan CO2 Emissions
Company name
Kerosene
(kl)
Kawashima Plant
Misato Plant
＊2
Honjo Facility
Kashima Plant
Tsukuba Research Laboratories
＊2 The Misato Plant was transferred to another company and was accordingly excluded from the Group as of March 31, 2015.
11
6
Establishment of a Recycling-Oriented Society
Total Waste for the Past Five Fiscal Years
Waste Reduction Results in Fiscal 2015
The Eisai Group in Japan is working to achieve zero
emissions and conducting waste disposal with three
goals in mind, specifically, reduce the amount of
waste generated, increase the amount of recycled
waste and decrease the amount of waste sent to
landfill. In fiscal 2015, we attained zero emissions
for the eighth consecutive fiscal year, and the total
amount of waste generated by the Eisai Group in
Japan declined 15.1% from fiscal 2014.
At the Kashima operational site, the volume
of industrial waste liquid increased along with
increased production. On the other hand, scrubber
waste liquid from fume hoods at the Tsukuba
Total Waste and the Ratio of Waste Sent
to Landfill to Total Waste Note
Total waste
Research Laboratories decreased due to a change
in the processing method. Additionally, we also
promoted the sale of wastepaper and valuable
metals and glass, which led to reductions in the
discharged amounts of these items. We reduced the
amount of waste sent to landfill by 69% from fiscal
2014 and the ratio of waste sent to landfill to total
waste declined sharply to 0.28%. By promoting the
sorting of waste for recycling and selecting excellent
waste disposal contractors through screening, the
recycling rate (including valuables) reached 57.7%,
an increase of 7.8% compared with fiscal 2014.
Recycled Waste and recycling rate
Ratio of waste sent to landfill to total waste
（％）
（t）
1.5
9,000
Amount recycled (including valuables)
Amount recycled
Recycling rate (including valuables)
Recycling rate
（％）
（t）
6,000
7,410
5,000
1.0
6,000
4,917
48.3
0.79
4,001
34.0
40
3,371
35.9
3,121
32.0
0.50
2,973
27.3
2,518
0.5
30
29.0
2,255
2,000
60
50
50.6
4,076
3,000
0.50
50.3
4,000
3,481
0.45
49.7
4,826
6,280
3,000
57.7
20
1,575
1,000
0.28
0
2011
2012
2013
Note: Corrected data from past by recount
2014
2015
0.0
(Fiscal year)
0
1,094
2011
2012
2013
2014
1,011
2015
10
0
Sludge
Waste oil
Waste acids and alkali
Waste plastic
Scrap metal
Glass and ceramic waste
Industrial waste and other
General waste
Amount of waste generated
Amount sold
Amount of waste generated and sold
FY2011
3,249
1,308
1,168
594
50
45
167
829
7,410
2,308
9,718
(tons)
FY2012
3,143
850
619
540
29
30
111
959
6,280
1,820
8,101
FY2013
2,523
764
327
491
37
40
109
626
4,917
1,546
6,463
FY2014
1,636
663
608
412
43
34
105
500
4,001
1,879
5,880
FY2015
1,276
744
756
313
18
22
122
232
3,481
2,360
5,841
Initiative for Recycling Resources
In order to establish a recycling-oriented society, it is
essential to reduce the amount of waste generated
in addition to reusing and recycling resources
such as metal, glass, waste oil and paper products
from waste. Based on this perspective, we actively
promote the sale of equipment and devices for
reuse as well as the recycling of scrap metal, glass
bottles and waste oil. Also, to reduce the total
amount of wastepaper, we are promoting the sale
of wastepaper while avoiding generation Initiative
for Recycling Resources of unnecessary waste by
devising better ways to proceed with meetings and
to copy documents.
In fiscal 2015, we expanded the scope of our
efforts to promote the sale of wastepaper in Japan
from operational sites and the head office to include
sales offices. We also continue to reuse organic
solvents, such as those used in the manufacture of
active pharmaceutical ingredients, and sell these as
auxiliary fuel.
Onsite Inspections of Waste-Processing Companies
The Eisai Group in Japan has been conducting
regular onsite inspections of its waste disposal
contractors. For the purpose of checking that waste
is being disposed of properly, inspections are
carried out for contractors engaged in the collection,
transport and intermediate processing of waste.
During fiscal 2015, over 50 onsite inspections were
conducted by the Eisai Group in Japan at sites
around the country, and it was confirmed that waste
is being disposed of in an appropriate manner.
For potential new contractors, we conduct
careful screening that includes onsite inspections.
At Eisai Co., Ltd., in particular, new contracts are
only signed after deliberation and approval by the
Company-Wide Environment and Safety Committee,
with priority given to government-certified excellent
industrial waste management contractors.
(Fiscal year)
12
7
Management of Chemical Substances
Proper Management of PRTR Substances
Chemical substances that are used in the research
and development and production of pharmaceutical
products include some substances subject to the
PRTR system that could have an impact on the
environment. The amounts of these substances
handled, released into the environment and
transferred as waste need to be understood and
properly managed. Therefore, in addition to using our
unique reagent management system to monitor the
usage of reagents by the Eisai Group in Japan, we are
also striving to reduce our usage of PRTR substances
and to control their release into the environment. With
regard to the usage of these substances exceeding
Actual Use of Substances Subject to the PRTR System
（t）
1,000
Amount handled
885
Amount released
800
656
566
600
400
326
200
0
499
477
263
70
18
2010
2011
210
211
191
35
17
28
2012
2013
2014
Volatile Organic Compounds ( VOCs) Release Control
the amount of the designated limit, we surely report
this matter to the locations of the relevant prefectural
governments without delay.
The amount of chemical substances used
depends largely on the volume of pharmaceutical
products produced. To maintain the quality of
active pharmaceutical ingredients, it is not easy
to change manufacturing conditions after entering
the commercial production phase. Therefore, we
try to reduce the amount of substances used and
utilize alternative solvents from the research and
development stage. At the same time, we actively
promote the reuse of organic solvents and incorporate
various means into the manufacturing processes
to minimize their release into the
Transfers
atmosphere.
The total amount of PRTR substances
handled by the Eisai Group in Japan
during fiscal 2015 decreased 4.6% from
476
fiscal 2014 to 476 tons. Notifications
were made to authorities for 10
substances, two more substances than in
86
37
fiscal 2014.
2015
(Fiscal year)
Fiscal 2015 PRTR Data for Eisai Group in Japan (Reported to Authorities)
Chemical name
Water-soluble zinc compounds
Acetonitrile
Ethylbenzene
Dichloromethane (also known as methylene chloride)
Substance
no.
Number of
operational
sites
Amount
handled
(tons)
Release
Into the
Into water
atmosphere
bodies
Transfer
As waste
To sewage
1
1
14.596
0.000
0.0442
1.107
0.000
13
3
12.873
0.064
0.000
12.809
0.001
53
1
13.430
0.000
0.000
2.21
0.003
186
1
222.291
32.724
0.000
26.957
0.000
N, N-dimethylformamide
232
1
2.122
0.000
0.000
2.122
0.000
Isophytol
269
1
161.690
0.000
0.000
3.278
0.000
Toluene
300
2
23.117
3.861
0.000
15.436
0.000
Pyridine
342
1
1.126
0.002
0.000
1.124
0.000
Hexane
392
1
15.773
0.237
0.000
15.536
0.000
Formaldehyde
411
1
3.674
0.229
0.000
1.012
0.000
VOCs, such as ethyl acetate, acetone and
methanol, are highly volatile and turn into gas in the
atmosphere, and as is the case with NOx discharged
from production plants, cause the generation of
photochemical oxidants. In view of preventing air
pollution, these substances need to be controlled to
reduce their release into the atmosphere.
In response, main production plants and research
facilities of the Eisai Group in Japan implement the
same level of efforts as for PRTR substances to reduce
the usage of VOCs and stipulate equipment operating
procedures to minimize their release from production
or research processes. The graph on the right shows
the amount handled and released into the atmosphere
of 55 substances (taken from the Ministry of the
Environment’s list of major 100 VOCs, excluding PRTR
substances) for the past five fiscal years.
The total amount of VOCs handled during fiscal
2015 was about 2.4 times as much as the amount
of PRTR substances handled. The total amount
of VOCs handled increased 23% over fiscal 2014
along with increased production volume at the
Kashima plant. However, the amount released into
the atmosphere was held to just 4.7% of the total
amount handled.
Amount of VOCs Released from Production Plants and
Research Facilities in Japan
（t）
2,500
Amount handled
2,431
Amount released into the atmosphere
2,000
1,512
1,500
1,132
1,000
927
922
719
487
500
174
0
2011
2012
2013
40
53
2014
2015
(Fiscal year)
Proper Management of Polychlorinated Biphenyl (PCB) Waste
We have made early application to Japan
Environmental Storage & Safety Corporation and
have been proceeding with the disposal of PCBcontaining and PCB-contaminated waste. During
fiscal 2015, we stored and managed mainly
fluorescent ballasts at the Kawashima Plant, Honjo
Facility, head office and sales offices and completed
the disposal of PCB waste stored at sales offices.
Also, along with the transfer of a storage building,
PCB waste of the head office was relocated to the
Honjo Facility. As a result, at the end of fiscal 2015
there were two PCB waste storage sites, the Honjo
Facility and Kawashima Plant. The table on the right
lists PCB waste by item.
As the disposal site for the fluorescent ballasts
stored in Tokyo and Saitama Prefecture was
changed from the JESCO Tokyo operational site
to the JESCO Hokkaido operational site, we have
completed re-registration for disposal of 661
fluorescent ballasts stored at the Honjo Facility.
Detoxification treatment is expected to commence
from fiscal 2017. We are reporting the storage
status without delay to the relevant prefecture
as required under the Law Concerning Special
Measures Against PCB Waste and are properly
storing PCB waste in enclosures with locks and
warning signs and with measures to prevent
vaporization, dispersion and leakage.
PCB waste still held by Eisai
Quantity
Low-concentration PCB waste (oil-extraction processing completed, casing only)
43
High-voltage capacitor
6
Low-voltage capacitor
3
Fluorescent ballast
665
Oil containing PCB
3 bags (37.5g)
Non-metallic contaminants (chemical resistant gloves, plastic containers)
3
13
8
Management of Fluorocarbons
Effective Use of Water Resources
At present, production of chlorofluorocarbons (CFCs),
which have a significant depletion effect on the
ozone layer, has been discontinued worldwide and
their concentrations in the atmosphere have been
declining after reaching a peak. Regulations have
also been implemented in regard to the production
of hydrochlorofluorocarbons (HCFCs), which have
a smaller depletion effect on the ozone layer. The
Eisai Group in Japan is systematically disposing of
and renewing equipment, and is promoting a shift
toward the use of hydrofluorocarbons (HFCs) and
non-fluorocarbons, which have no depletion effect on
the ozone layer.
A survey conducted in fiscal 2015 on the amount
of fluorocarbons used at the Eisai Group in Japan’s
principal production plants and research facilities
shows that total use of fluorocarbons declined 5.3%
from 27.5 tons in fiscal 2013 to 26.0 tons. As a
percentage, the use of CFCs declined to 0.14% of
total usage. Similarly, the use of HCFCs declined
13.6% over this same period from 6.0 tons to 5.2
tons and the use of HFCs declined 2.9% from 21.4
tons to 20.7 tons. The switch to HFCs is progressing
steadily and HFC accounted for 79.8% of total usage.
The change to and use of non-fluorocarbons is a
minimal amount.
Although HFCs have no depletion effect on
the ozone layer, these have a strong greenhouse
effect. For this reason, we carry out regular rigorous
inspections to prevent leaks from equipment. At the
same time, in the unlikely event that a leakage-related
accident occurs, we immediately share information on
the incident and strive to prevent a recurrence of the
incident. Furthermore, when disposing of equipment,
we process all items strictly in accordance with the
Fluorocarbons Recovery and Destruction Law. The
above-mentioned survey revealed that the amount
of fluorocarbons used at the Eisai Group in Japan’s
principal production plants and research facilities was
equivalent to 45,034 tons of CO2 when converted on
a CO2 basis.
The Act on Rational Use and Proper Management of
Fluorocarbons went into effect from April 2015. Eisai
Co., Ltd. steadily implemented regular inspections
that also included offices for leakage of fluorocarbons
from Class 1 Specified Products (commercial air
conditioners and refrigeration and freezer equipment)
that are subject to the Act. As a result, the calculated
volume of leakage in fiscal 2015 amounted to 500.4
tons of CO2eq., which was below the threshold for
notifying the Ministry of Health, Labour and Welfare.
Fluorocarbon Usage
Carbon Dioxide Equivalent
（kg）
FY2013
25,000
FY2015
45,034
20,000
6,026
5,000
70
CFC
5,212
2
37
HCFC
HFC
Type of Fluorocarbons
8,744
10,000
NON
4
0
326
0.01
CFC
HCFC
HFC
NON
Type of Fluorocarbons
Total
plants and reusing wastewater. In addition, we
have established a framework for preventing the
contamination of groundwater at Eisai production
plants and research facilities in Japan in response to
the Water Pollution Control Law.
In a survey carried out at the Eisai Group both in
and outside Japan, we confirmed that none of our
production plants or research facilities are situated in
areas with a high risk of having to stop operations due
to water shortages in the near future.
Eisai Group Water Consumption and Amount of Wastewater
Water Consumption
(1,000m3)
4,000
3,786
3,000
Amount of Wastewater
3,820
3,562
3,225
2,948
3,125
3,388
3,314
2,684
2,716
2,000
1,000
0
2012
2013
2014
2015 (Fiscal year)
Green Purchasing
As one environmental effort undertaken by employees
on a daily basis, the Eisai Group in Japan is promoting
green purchasing, an initiative to purchase what is
needed in the quantity needed, and if there are two
products equivalent in both quality and price, to give
preference to the one that is more environmentfriendly. The initiative is designed to shift away from a
35,964
30,000
10,000
0
（t-CO2）
50,000
40,000
15,000
In recent years, the number of regions suffering from
severe water shortages due to climate change and
other environmental changes has been increasing
worldwide and the importance of effective use of
water resources is rising year by year. As the sufficient
acquisition of water resources is absolutely essential
for the production of high-quality pharmaceuticals,
Eisai is working to ensure the quality of water
discharged from its production plants and research
facilities and is also implementing initiatives to reduce
water consumption. We have an acute awareness of
the need to conserve water and are taking such steps
as minimizing consumption of water for production
2011
21,352 20,738
20,000
Saving Resources
society of mass-production and mass-consumption.
Eisai Co., Ltd., in particular, has been actively
committed to this initiative through participation in the
Green Purchasing Network＊ and in accordance with
its own Green Purchasing Guidelines.
＊ A network of companies, local governments and consumer groups
(private organizations) supporting the concept of green purchasing
14
■Magnified scale
9
Soot
and dust
2011
0.9
2012
0.7
2013
4.0
5.5
3.3
0.5
Air Pollutant Emissions and Pollutant Load in Wastewater
2014
4.3
0.4
2015
0.3
0
3.9
1
2
3
4
Air Pollutant Emissions
Pollutant Load in Wastewater
■Eisai Group in Japan　■Group Companies outside Japan
■Eisai Group in Japan　■Group Companies outside Japan
0
10
20
40 (tons)
30
(Fiscal year)
2011
2012
SOx
2013
2014
2015
NOx
2.4
0.6
BOD
2012
11.8
2013
10.4
2014
10.2
22.1
21.6
0.9
2012
0.7
2014
2015
Nitrogen
25.5
7.3
2014
8.0
0.3
0
Phosphorus
3.9
2
8.2
2013
4.7
2014
3.0 1.2
2015
3.0 1.2
2013
0.2
2014
0.2
0.1
0.3
0.1
2015
3
4
5
6
7
0
3,661
200
2,104
55
34
1,535
4
631
7,300
259
North Carolina Plant
61
4,039
298
Andover Research Institute
20
2,980
230
30
3,390
260
7,279
11,233
3,103
Subtotal
7,390
21,642
3,890
Total
8,021
28,942
4,150
Pollutant Load in Wastewater in Fiscal 2015 by Site
4.2
0.2
Soot and
dust (kg)
–
Group
Morphotek Inc.
Companies
outside Japan Vizag Plant
2.3
NOx (kg)
597
Subtotal
4.2
2012
4.3
1
4.4
SOx (kg)
Eisai Group in Tsukuba Research Laboratories
Japan
Sannova Co., Ltd. and others
Category
Eisai
Group in
Japan
■Magnified scale
3.3
0.4
Operational site/Company
4.2
7.6
2012
4.0
5.5
0.5
Category
6.0
23.6
2011
2013
7.7
18.8
■Magnified scale
Soot
and dust
20 (tons)
5.2
2013
2015
7.4
12.4
15
Kawashima Plant
6.8
2012
7.5
1.3
10
6.4
6.3
1.4
7
(Fiscal year)
6.6
1.8
6
Air Pollutant Emissions in Fiscal 2015 by Site
5
7.7
2011
2015
0
5
0.8
0.7
Operational site/Company
2
COD
(kg)
Nitrogen Phosphorus
(kg)
(kg)
Kawashima Plant
3,406
Tsukuba Research Laboratories
3,757
–
–
Kashima Plant
112
224
Honjo Facility
211
Sannova Co., Ltd. and others
100
Subtotal
7,586
508
3,031
90
North Carolina Plant
2,095
–
–
–
1,346
278
Group
Morphotek Inc.
Companies
Suzhou Plant
outside
Vizag Plant
Japan
1
BOD
(kg)
237
–
–
2,770
45
–
–
–
–
–
53
15
284
208
30
166
7
29
22,511
–
–
Subtotal
2,332
22,511
1,512
314
Total
9,918
23,019
4,543
404
–
Note: “–” indicates that no measurement was taken.
■Eisai Group in Japan　■Group Companies outside Japan
15
10
Resource Input and Environmental Impact (Eisai Group in Japan)
Kawashima Plant
Kashima Plant
2013
2014
2015
Energy consumption
Electricity (MWh)
34,233
31,996
49
23
28
4,350
3,923
4,228
Amount generated (tons)
628
812
596
Amount generated (tons)
Recycled amount (tons)
104
73
63
Amount sent to landfill (tons)
0.2
0.1
0.1
Liquefied petroleum gas (LPG) (tons)
2014
2015
Energy consumption
35,371
Processed natural gas (tons)
KAN Research Institute, Inc.
2013
Waste treatment
Electricity (MWh)
2014
11,329
11,591
7
7
1
39,337
39,056
40,181
1,020
1,101
1,405
Recycled amount (tons)
309
224
460
Amount sent to landfill (tons)
Amount sent to landfill (tons)
0.0
0.0
0.0
Air pollutant emissions and pollutant load in wastewater
Liquefied petroleum gas (LPG) (tons)
Air pollutant emissions and pollutant load in wastewater
2013
2014
2015
13
15
15
7
6
15
144
162
162
Kawashima Plant
11,515
Industrial steam (tons)
2015
Energy consumption
Waste treatment
Air pollutant emissions and pollutant load in wastewater
Principal PRTR Substances Handled
2013
Electricity (MWh)
700
3,020
3,274
Processed natural gas (tons)
112
499
383
Waste treatment
Water-soluble zinc compounds (tons)
Toluene (tons)
Isophytol (tons)
Amount generated (tons)
22
28
36
Recycled amount (tons)
5
7
7
0.5
0.7
0.7
SOx (kg)
–
–
–
SOx (kg)
969
1,005
597
SOx (kg)
–
–
NOx (kg)
–
–
–
NOx (kg)
5,019
6,014
3,661
NOx (kg)
–
–
Soot and dust (kg)
–
–
–
Tsukuba Research Laboratories
Acetonitrile (tons)
3
2
2
Dichloromethane (tons)
0.6
0.7
1.0
Hexane (tons)
0.4
0.7
0.5
14
13
9
6
7
13
222
Kashima Plant
Acetonitrile (tons)
Ethylbenzene (tons)
314
352
200
–
–
Water consumption (1,000 m3)
4
14
Water consumption (1,000 m3)
2,695
2,471
2,635
Water consumption (1,000 m3)
51
48
49
Recycled water (1,000 m3)
–
5
3
Dichloromethane (tons)
88
182
Wastewater discharge (1,000 m3)
2,348
2,142
2,211
Wastewater discharge (1,000 m3)
78
48
56
Wastewater discharge (1,000 m3)
2
15
15
Toluene (tons)
84
54
8
Formaldehyde (tons)
1.3
2.0
3.7
82
48
15
Acetonitrile (tons)
0.8
0.4
1.0
Dichloromethane (tons)
0.1
0.1
0
Soot and dust (kg)
Soot and dust (kg)
15
BOD (kg)
3,701
3,941
3,406
BOD (kg)
405
368
112
BOD (kg)
–
–
15
Nitrogen (kg)
3,941
2,698
2,770
Nitrogen (kg)
–
–
–
Nitrogen (kg)
–
–
–
Hexane (tons)
55
33
45
Phosphorus (kg)
–
–
–
Phosphorus (kg)
–
–
–
Sannova Co., Ltd.
Phosphorus (kg)
Tsukuba Research Laboratories
Sannova Co., Ltd.
2013
2014
2015
29,607
27,692
26,465
2,663
2,262
1,940
67
50
56
Energy consumption
Electricity (MWh)
Processed natural gas (tons)
Fuel oil A (kl)
“–” indicates that no measurement was taken.
2013
2014
2015
11,431
11,494
11,424
1,202
1,198
1,149
3
4
3
619
Energy consumption
Waste treatment
Electricity (MWh)
Processed natural gas (tons)
Fuel oil A (kl)
261
334
239
Amount generated (tons)
815
761
Recycled amount (tons)
148
160
124
Recycled amount (tons)
111
100
84
Amount sent to landfill (tons)
0.6
0.6
0.5
Amount sent to landfill (tons)
0.0
0.0
0.0
Air pollutant emissions and pollutant load in wastewater
371
258
–
SOx (kg)
–
–
–
NOx (kg)
3,600
2,723
2,104
NOx (kg)
1,732
1,376
1,535
Soot and dust (kg)
216
63
55
Water consumption (1,000 m3)
169
184
178
74
77
64
144
158
178
2,845
3,278
3,757
Nitrogen (kg)
–
–
Phosphorus (kg)
–
–
BOD (kg)
10
12
9.5
Chloroform (kg)
1.4
1.9
1.2
Formaldehyde (kg)
2.6
3.7
2.4
Air pollutant emissions and pollutant load in wastewater
SOx (kg)
Wastewater discharge (1,000 m3)
Xylene (kg)
Waste treatment
Amount generated (tons)
Recycled water (1,000 m3)
KAN Research Institute, Inc.
–
–
–
Water consumption (1,000 m3)
67
64
60
Wastewater discharge (1,000 m3)
47
46
45
BOD (kg)
64
55
55
157
180
175
18
31
30
Soot and dust (kg)
Nitrogen (kg)
Phosphorus (kg)
16
11
Resource Input and Environmental Impact
(Group Companies outside Japan)
Eisai Inc., North Carolina Plant (North Carolina, U.S.)
2013
Energy consumption
Electricity (MWh)
Natural gas (decatherms＊1)
Light oil (kl)
Waste treatment
Amount generated (U.S. tons＊2 )
Recycled amount (U.S. tons)
Amount sent to landfill (U.S. tons)
Air pollutant emissions
SOx (kg)
NOx (kg)
2014
Eisai Inc., Andover Research Institute (Massachusetts, U.S.)
2015
20,035
140,759
10
26,012
147,408
10
11,908
76,720
5
237
53
583
118
314
63
143
438
236
110
7,570
140
7,680
61
4,039
Soot and dust (kg)
Pollutant load in Wastewater
540
590
298
Water consumption (1,000 m3)
Wastewater discharge (1,000 m3)
201
167
71
BOD (kg)
86
2,780
97
5,312
38
2,095
Nitrogen (kg)
Phosphorus (kg)
3,399
682
687
184
1,346
278
Eisai China Inc., Suzhou Plant (Jiangsu, China)
2013
Energy consumption
Electricity (MWh)
Natural gas (1,000m3)
Fuel oil A (kl)
Waste treatment
Amount generated (U.S. tons)
Recycled amount (U.S. tons)
Amount sent to landfill (U.S. tons)
Air pollutant emissions
SOx (kg)
NOx (kg)
Soot and dust (kg)
Pollutant load in Wastewater
Water consumption (1,000 m3)
Energy consumption
Electricity (MWh)
2015
10,022
10,520
Waste treatment
Amount generated (tons)
857
9,108
1,031
10,290
1,080
11,293
Waste treatment
Amount generated (tons)
Recycled amount (tons)
131
105
270
227
257
225
Amount incinerated (tons)
27
43
32
Pollutant load in Wastewater
Water consumption (1,000 m3)
Wastewater discharge (1,000 m3)
Phosphorus (kg)
51
41
11
42
34
–
60
48
29
2013
9,327
Liquefied natural gas (LNG) (tons)
Industrial steam (tons)
2014
PT Eisai Indonesia, Bogor Plant (West Java, Indonesia)
2013
Energy consumption
Electricity (MWh)
Fuel oil A (kl)
Liquefied petroleum gas (LPG) (tons)
Waste treatment
Amount generated (tons)
Recycled amount (tons)
Amount sent to landfill (tons)
Pollutant load in Wastewater
Water consumption (1,000 m3)
Wastewater discharge (1,000 m3)
BOD (kg)
Phosphorus (kg)
2014
2015
1,503
1,055
1,045
3
1
1
1
2
1
17
11
12
17
0
11
0
12
0
7.2
1.2
4.1
6.0
6.0
0.8
1.9
2.6
5.0
0.6
5.5
1.1
Recycled amount (tons)
Amount sent to landfill (tons)
Pollutant load in Wastewater
Water consumption (1,000 m3)
Wastewater discharge (1,000 m3)
13,800
2,417
5
10,680
1,893
3
9,254
1,124
2
203
123
106
35
–
34
46
25
39
50
4,290
20
3,210
20
2,980
300
240
230
50
30
28
Natural gas (decatherms)
Light oil (kl)
Waste treatment
Amount generated (U.S. tons)
Recycled amount (U.S. tons)
Amount sent to landfill (U.S. tons)
Air pollutant emissions
SOx (kg)
NOx (kg)
Soot and dust (kg)
Pollutant load in Wastewater
Water consumption (1,000 m3)
Wastewater discharge (1,000 m3)
BOD (kg)
Nitrogen (kg)
Phosphorus (kg)
2015
6,892
909
7
6,685
856
0
5,856
800
4
244
160
155
Energy consumption
244
0
160
0
155
0
Electricity (MWh)
Natural gas (decatherms)
Waste treatment
19
19
20
20
21
21
2014
2015
9,922
726
4
10,395
626
4
10,305
486
5
Waste treatment
Amount generated (tons)
Recycled amount (tons)
196
133
212
184
140
118
Amount incinerated (tons)
64
28
22
6,033
6,240
7,350
11,095
7,279
11,233
2,122
3,260
3,103
99
94
93
50
23,378
47
19,390
36
22,511
Energy consumption
Soot and dust (kg)
Pollutant load in Wastewater
Water consumption (1,000 m3)
Wastewater discharge (1,000 m3)
COD (kg)
Energy consumption
Electricity (MWh)
2014
2013
Air pollutant emissions
SOx (kg)
NOx (kg)
2013
2013
Eisai Knowledge Centre, India (Andhra Pradesh, India)
Electricity (MWh)
Light oil (kl)
Liquefied petroleum gas (LPG) (tons)
Morphotek Inc., (Pennsylvania U.S.) Note
2015
European Knowledge Centre (Hertfordshire, U.K)
Natural gas (1,000m3)
Fuel oil A (kl)
Energy consumption
Electricity (MWh)
2014
Principal Chemical Substances Used
2014
2015
8,726
9,045
9,151
55,380
20
55,016
1
42,930
8
164
177
177
45
96
50
106
50
106
60
4,100
32
3,470
30
3,390
310
255
260
40
42
37
23
1,374
26
1,386
22
237
755
36
510
–
166
7
Note: Corrected data from past by recount
H3 Biomedicine Inc. (Massachusetts, U.S. )
Amount generated (tons)
Recycled amount (tons)
Amount sent to landfill (tons)
2013
2014
2015
3,177
3,314
3,618
1,547
4,082
4,902
46
11
1
71
4
1
105
5
–
69
69
11
83
83
–
9.1
9.1
29
Pollutant load in Wastewater
Water consumption (1,000 m3)
Wastewater discharge (1,000 m3)
Phosphorus (kg)
＊1 O
ne decatherm = 1,055 MJ
＊2 O
ne U.S. ton = 0.907185 metric tons
“–” indicates that no measurement was taken.　North Carolina Plant
Isopropanol (tons)
Methanol (tons)
Acetonitrile (tons)
Sulfuric acid (tons)
Sodium hydroxide (tons)
Suzhou Plant
Ethanol (tons)
Methanol (tons)
Acetonitrile (tons)
Ethyl acetate (tons)
Bogor Plant
Methanol (l)
Acetonitrile (l)
Anhydrous ethanol (l)
Andover Research Institute
Methanol (U.S. tons)
Ethyl acetate (U.S. tons)
Acetonitrile (U.S. tons)
Heptane (U.S. tons)
Dichloromethane (U.S. tons)
Methyl-t-butyl ether (U.S. tons)
European Knowledge Centre
Acetonitrile (tons)
Methanol (tons)
Ethanol (tons)
Eisai Knowledge Centre, India
Ethyl acetate (tons)
Acetone (tons)
Ethylbenzene (tons)
Methanol (tons)
Ethanol (tons)
Aluminum chloride (tons)
Piperidine hydrochloride (tons)
Propionyl chloride (tons)
Tetrahydrofuran (tons)
Paraformaldehyde (tons)
N, N-dimethylformamide (tons)
Morphotek Inc.
Decon Quat 100 (quaternary ammonium solution) (l)
Decon AHOL (70% isopropyl alcolol solution) (l)
Decon Spore (l)
Decon Clean (residual remover) (l)
Ethanol (l)
H3 Biomedicine Inc.
Acetonitrile (tons)
Dichloromethane (tons)
Acetone (tons)
Ethyl acetate (tons)
Hexane (tons)
2013
2014
2015
0.3
0.7
0.2
0.3
1.1
–
–
–
2.3
0.4
–
–
–
–
–
17.3
0.4
0.3
0.1
27.2
0.8
0.4
0.1
27.8
0.5
0.4
0.1
245.0
97.0
47.9
194.0
74.5
34.2
247.5
78.5
24.9
7.7
7.1
2.4
4.5
0.9
2
1.5
2.7
2.6
2.8
2.3
0.7
1.3
3.7
1.7
3.1
1.4
0.6
0.8
0.3
0.1
0.3
0.1
0.1
0.2
0.2
0.1
78.2
76.4
25.3
24.1
8.4
15.2
11.2
8.2
8.9
3.2
0.2
70.7
60.5
13.9
16.0
4.6
10.9
11.3
8.4
4.8
2.8
0.9
26.5
37.0
13.2
14.7
5.9
4.2
3.9
2.9
3.2
1.1
4.4
4,952
5,900
2,605
1,439
400
2,450
1,940
295
13,628
1,499
1,363
1,363
374
1.6
1.5
0.8
0.6
0.6
2.9
1.1
1.1
1.1
1.2
0.6
0.5
0.5
0.5
17
12
Third-Party Verification of Greenhouse Gas Emissions Volume
Eisai Co., Ltd. undergoes third-party verifications to improve the accuracy of measurement, aggregation,
calculation and reporting methods for the amounts of greenhouse gasses emitted by the Group. In fiscal
2016, five business operational sites in Japan and eight business operational sites outside Japan, centering
on production plants and research facilities, underwent verifications for Scope 1 emissions and Scope 2
emissions.
18