The low-down on DXA scanning Nurses should have the knowledge and education to request DXA scans and instigate early treatment, writes Susan Vanderkamp O Nurses working in many different specialities encounter osteoporosis. All too often, osteoporosis is undetected until a fracture occurs, and when this happens, it is a matter of treating to prevent further fracture. In an ideal healthcare system, nurses who work in primary and secondary care should have the knowledge and education regarding osteoporosis prevention to detect those who are at risk of osteoporosis, to request a DXA in those patients, and to instigate early treatment and future fracture prevention. steoporosis is a reduction in the strength of bone that predisposes to fracture. Osteoporosis is defined as a chronic systemic skeletal disease characterised by low bone mass and micro-architectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture.1 It is a silent disease until it manifests with fracture, especially in the spine, wrist and hip. Osteoporotic fractures arise through a combination of reduced bone strength and trauma. A low-trauma fracture at one skeletal site is a strong predictor of fractures at other sites. Early detection of osteoporosis is possible by measuring bone mineral density (BMD) using a dual-energy x-ray absorptiometry (DXA) machine. Osteoporosis is not the preserve of any one medical speciality but many (endocrinology, geriatrics, gynaecology, rheumatology and general practice). It often falls between stools and is not recognised as a serious life-threatening condition. Setting up a DXA nurse-led service Setting up a DXA centre is a challenge to the service provider in that it entails undertaking considerable research and hard work into how it can be run and managed in keeping with international guidelines. Wherever a bone density unit is located – hospital-based or in general practice – certain standards have to be adhered to. 12 3. Nurse led DXA/SS/NH2 2 30/09/2008 11:00:08 referral form, or by a GP who has sent a referral letter. It is illegal to scan without a referral letter. An information booklet regarding the DXA procedure and osteoporosis, including information on treatments, is an ideal way of imparting information on osteoporosis and should be a back-up to the patient interview and DXA scan. It is preferable to ask the patient to complete an assessment questionnaire that outlines risk factors and medications. In 1994, a WHO technical report introduced a classification system for osteoporosis based on BMD measurement at the femoral neck – namely, the T-score, which is a means of expressing the result in standardised units according to the reference population of healthy young adults.3 In 2008, the same WHO group introduced FRAX, that shifts the clinical paradigm from risk categorisation to fracture-risk estimation in adults.4 The 10-year per cent probabilities of hip and major osteoporotic fractures are calculated by combining a T-score result with risk factors (age, previous fracture, parent fractured hip, current smoking, alcohol intake, glucocorticoids and rheumatoid arthritis). A typical scan session with a patient takes approximately 30 minutes. Within this half-hour allocation, the patient receives an education assessment in relation to diet, lifestyle, exercise and fall prevention, as well as information regarding any medications which they may be prescribed. There are rules relating to medication ingestion which need to be observed, eg. the use of bisphosphonates requires taking the medication in the fasting state with a 200ml glass of plain water, not fruit juice or milk. When taking two calcium supplements, the doses should be divided into one supplement in the morning and one in the evening. Knowledge of these rules enables better understanding of medication by the patient and helps towards better compliance. Compliance with medication is low, especially with bisphosphonate use. Nurse education on giving a patient One of the biggest challenges for nurses working in the area has been in relation to radiation protection, which traditionally has not been part of nurse training. In 2006, draft legislation (Statutory Instrument 478 [section 13.2]) allows any person who has undertaken a radiation protection course to work with radiation. This draft document has established a pathway that permits nurses to operate DXA machines. All personnel involved in running a DXA unit have to be trained in DXA scanning technique, and have to attend a course in radiation protection; this should be repeated at two-yearly intervals. Initial manufacturer training by the company providing the DXA machine is provided to start off training and the rule of thumb is to scan, scan and scan as many patients as possible to build up experience. It is normal that when a 100 or more scans have been carried out, further training with certification should be undertaken. The nearest training centre for Ireland is in the UK and there is strong collaboration between the two countries. Most nurses working in DXA in Ireland undergo a certification exam with the National Osteoporosis Society in the UK. When a new nurse starts working in a unit, it is usual to have a two-week training period with the longest trained nurse in the unit to build up experience. Department protocol A department working protocol is necessary for the day-to-day running of DXA centres and should be based on the most up-to-date international guidelines. The International Society for Clinical Densitometry (www.iscd.org) has recently updated its official positions.2 This is a not-for-profit multidisciplinary professional society; its mission is to advance excellence in the assessment of skeletal health by standard setting, increasing patient awareness and continuing medical education Holistic procedure In most centres, patients are referred for a DXA scan by a physician who has written a DXA 13 3. Nurse led DXA/SS/NH2 3 30/09/2008 11:00:08 Simple walking is safe for everyone. Much time is spent ‘thinking’ about getting up and going for a walk, but it can be as simple as walking to the local shop for the newspaper and walking back, instead of driving in a car. Swimming provides good aerobic exercise, and helps with pain relief after fractures, but it is not a weight-bearing exercise. Having input from a dietitian is ideal to emphasise the importance of daily calcium through the diet (milk, cheese and yoghurts) and daily intake of vitamin D, (mackerel, sardines, cereals, margarine spreads) which aids calcium absorption. Being outside pottering in the garden while being exposed to early morning or late afternoon sunlight, between April and October for 10 minutes a day is usually sufficient for top-up of vitamin D levels (it is wise to avoid midday sun). Many people, due to restrictive dieting or excessive caffeine intake (more than five cups of strong tea/coffee per day), run the risk of developing osteoporosis. Too much caffeine increases urinary calcium excretion. With excess alcohol intake, calcium absorption is hindered, and often combinations of dieting, with an excess of alcohol and an absence of dietary dairy calcium, sets the stage for the development of bone loss later in life. For the elderly patient, advice on safety at home with a view to fall prevention from a community occupational therapist cannot be emphasised enough. The occupational therapist, by helping the patient to focus on activities of daily living, self-care and leisure, aims to enable the patient to be as independent as possible in their day-to-day lives. By adapting the environment or specific tasks, maximum independence and quality of life is enhanced. For example, insertion of an extra rail on stairways, or rails in the bathroom, non-slip bathmats or use of bathboards can help. Community services available such as ‘disabled a good understanding of their medications may improve compliance. The scan time itself is quite short (approximately two minutes). Clothing adjustments for any metal artefacts such as belts or buttons or bra wires also has to be factored in and providing gowns is wise to avoid unnecessary artefacts within the regions of interest scanned. The effective radiation dose to patients following scanning procedure of the spine and hip is the equivalent of one day’s natural background radiation; thus it is quite low. Height and weight are also recorded before the scan. Multidisciplinary approach Information on lifestyle changes – such as cessation of smoking, assessment of alcohol use (14 units for a woman and 21 units for a man), patient education in relation to prevention of osteoporosis by healthy eating habits and fall prevention – all form part of the osteoporosis session. A multidisciplinary approach that includes advice about both medications and means of optimising bone health by exercise, diet, and activities of daily living (fall prevention) is beneficial. Input from a chartered physiotherapist to whom the patient can be referred on a finding of osteoporosis, or for an elderly patient who has a tendency to fall, is extremely helpful. From childhood to the mid-20s, exercise is vital in maximising peak bone mass, a key determinant of bone mass later in life. In later life, exercise can help to slow down the normal loss of bone density, and is necessary to general health. Exercise improves muscle strength and flexibility, improves balance and co-ordination, thus reducing the risk of falls. Weight-bearing and muscle-strengthening exercises, targeting arms, legs and trunk, or posture and balance exercises, eg. pilates, or Tai Chi, all go towards maintaining better bone strength. 14 3. Nurse led DXA/SS/NH2 4 30/09/2008 11:00:09 pa ti en persons grant’, pendant alarms, and ‘security for the elderly’, all go towards an independent lifestyle, particularly for those living alone. maintenance has to be factored into a department’s or a practice’s overheads. The maintenance is normally carried out by the service agent providing the machine. If a machine is moved or relocated from one area to another, it is necessary for recalibration to be carried out by the company. It is important that service logs are maintained and available for inspection. Quality assurance Precision assessment Finally, all DXA units have to be registered with the Radiological Institute of Ireland (RPII). A copy of local radiation rules should be on display on the office wall at all times. The cornerstone of operation in a DXA unit is the quality control for DXA scanning. Within this remit there are operator-dependent factors (training) and scanning dependent factors. The scanning dependent factors include in particular the scanning of ‘phantoms’ on a daily basis in order to monitor instrument performance and calibration, namely instrument quality control (IQC). The performance of IQC following manufacturer’s instructions must be adhered to. Attention to the correct positioning of the phantom, with acquisition and scan analysis of results is important. The phantom should be scanned each day that a patient is scanned, and for DXA systems at least three times a week. Inspection of QC results is carried out to ensure they are within the accepted laid down parameters, as any deviation on the QC reading can invalidate or compromise patient results. In the event that there is a deviation from the norm, the phantom should be re-scanned three more times and if it is still outside expected parameters, scanning of patients should be discontinued and the service company should be called out to inspect the machine. The regular archiving of hard copies of the QC results is also necessary for the reason that inspection of these results may be required, as part of record keeping and if site inspection takes place by the RPII. Like all equipment, DXA equipment requires twice annual maintenance and budgeting for this DXA centres should carry out a precision study to determine its precision error and calculate the ‘least significant change’. This answers the question about the significance of changes between two sets of scans. The precision error supplied by the manufacturer is not adequate in this regard. If a DXA centre has more than one operator, an average precision error, combining data from all operators should be used to establish precision error and LSC for the centre, provided the precision error for each operator is within a pre-established range of acceptable performance. Every operator should do one complete precision assessment after basic scanning skills have been learned and after having performed approximately 100 patient scans. Precision assessment should be standard clinical practice. n Susan Vanderkamp is clinical nurse specialist in osteoporosis, St Vincent’s University Hospital, Dublin pa ti en t GP pa ti ent Sp ecia l i st References 1. Nih Consensus Development Panel on Osteoporosis Prevention D, Therapy. Osteoporosis Prevention, Diagnosis, and Therapy. JAMA 2001;285:785-95 2. Baim S, Binkley N, Bilzekian J, et al. Official positions of the International Society for Clinical Densitometry and executive summary of the 2007 ISCD Position Development Conference. J Clin Densitom 2008;11:75-91 3. Organization WH. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. WHO Technical Report Series 843 WHO, Geneva 1994 4. Kanis J, Johnell O, Oden A, Johansson H, McCloskey E. FRAXTM and the assessment of fracture probability in men and women from the UK. Osteoporos Int 2008;19:385-97 15 3. Nurse led DXA/SS/NH2 5 30/09/2008 11:00:09
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