•Fluorine is often used as a molecular tag
How does it work?
•Coming in version 1.1 of the Spinsolve software, we will offer a 1D Fluorine protocol
•No hardware changes are required, old systems can be upgraded easily
•Proton and Fluorine experiments can be run on the same sample, without further adjustments
Example spectra
k Spinsolve
1H
FLUORINE AND PROTON BENCHTOP
NMR ON THE SAME SYSTEM
19F
spectroscopy
R sensitivity is very high
al industry
The Spinsolve benchtop NMR spectrometer can measure both Fluorine and Proton.
Unlike traditional NMR systems, no complicated retuning of the probe is required.
a 1D Fluorine protocol
d easily
e, without further adjustments
Why use Fluorine NMR?
The 19F nucleus is one of the most important nuclei for
NMR spectroscopy. Due to its 100% natural abundance
and high frequency its NMR sensitivity is very high.
Organofluorine compounds are often used in the
pharmaceutical industry and Fluorine is often used as a
molecular tag.
Measuring 19F on the Spinsolve benchtop NMR
• Included in version 1.1 of the Spinsolve software is a 1D Fluorine experiment.
• No hardware adjustment is required.
• Proton and Fluorine experiments can be run on the same sample with a click of the button.
Spinsolve v1.1 software showing a single scan 19F acquisition of 5-bromo-1,2,3-trifluorobenzene
Fluorine NMR now available for Magritek Spinsolve
Fluorine NMR now available for Magritek Spinsolve
Why use Fluorine NMR?
•The 19F nucleus is one of the most important nuclei for NMR spectroscopy
Why
useitsFluorine
NMR?
R
•Due to
100% natural
abundance
and high frequency its NMR sensitivity is very high
•The
19F
nucleus
is
one
of
the
most
important
nuclei
for NMR spectroscopy
•Organofluorine compounds are often used in the
pharmaceutical
industry
•Due
to
its
100%
natural
abundance
and
high
frequency
its
NMR
sensitivity
is very high
•Fluorine is often used as a molecular tag
•Organofluorine compounds are often used in the pharmaceutical industry
•Fluorine
used as a molecular tag
How
doesisit often
work?
•Coming in version 1.1 of the Spinsolve software, we will offer a 1D Fluorine protocol
How
does it work?
•No hardware
changes are required, old systems can be upgraded easily
•Coming
in
version
of the Spinsolve
willsample,
offer a 1D
Fluorine
protocol
•Proton and Fluorine1.1
experiments
can besoftware,
run on thewesame
without
further
adjustments
•No hardware changes are required, old systems can be upgraded easily
Example
•Proton
and spectra
Fluorine experiments can be run on the same sample, without further adjustments
Example of both Proton and Fluorine NMR on the same sample
1H
Example
spectra
2, 2, 2-trifluoroethanol
19F
1
1919F
1
H H
F
5-bromo-1,2,3-trifluorobenzene
1
19
H
F
CONTACT INFORMATION
For further information, please contact: [email protected]
GERMANY
NEW ZEALAND
Philipsstraße 8
52068 Aachen, Germany
Tel: +49 (241) 70525-6000
Fax: +49 (241) 963 1429
Or visit our website www.magritek.com
6 Hurring Place, Unit 3
Newlands, Wellington 6037, NZ
Tel: +64 4 477 7096
Fax: +64 4 471 4665
UNITED STATES
6440 Lusk Blvd (D108)
San Diego, CA 92121, USA
Tel: +1 (855) 667-6835
+1 (866) NMR-MTEK