Anti-SLIT1 monoclonal antibody, clone FQ6808(3)
Cat.No: DCABH-4246
Lot. No. (See product label)
PRODUCT INFORMATION
Product Overview
Rabbit monoclonal to Slit1
Antigen Description
Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated
by interaction with roundabout homolog receptors. During neural development involved in axonal
navigation at the ventral midline of the neural tube and projection of axons to different regions (By
similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by
acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the
olfactory bulb.
Immunogen
Synthetic peptide, corresponding to residues in Human Slit1 (UniProt: O75093).
Isotype
IgG
Source/Host
Rabbit
Species Reactivity
Human
Clone
FQ6808(3)
Purity
Tissue culture supernatant
Conjugate
Unconjugated
Applications
WB
Positive Control
Human fetal brain lysate.
Format
Liquid
Size
100 μl
Buffer
Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Storage
Store at -20oC.
Ship
Shipped at 4°C.
Antigen Gene Information
Gene Name
SLIT1 slit homolog 1 (Drosophila) [ Homo sapiens ]
Official Symbol
SLIT1
Synonyms
SLIT1; slit homolog 1 (Drosophila); SLIL1, slit (Drosophila) homolog 1; slit homolog 1 protein; MEGF4;
Slit 1; slit1; SLIT3; multiple EGF-like domains protein 4; multiple epidermal growth factor-like domains
protein 4; SLIL1; SLIT-1; MGC164811;
Entrez Gene ID
6585
mRNA Refseq
NM_003061
Protein Refseq
NP_003052
Creative Diagnostics. All rights reserved
45-1 Ramsey Road Shirley, NY 11967, USA
Tel: 1-631-624-4882 Fax: 1-631-938-8221
E-mail: [email protected]
www.creative-diagnostics.com
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MIM
603742
UniProt ID
A6H8V1
Chromosome Location 10q23.3-q24
Pathway
Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance,
organism-specific biosystem; Developmental Biology, organism-specific biosystem; Netrin-1 signaling,
organism-specific biosystem;
Function
Roundabout binding; calcium ion binding; heparan sulfate proteoglycan binding;
Creative Diagnostics. All rights reserved
45-1 Ramsey Road Shirley, NY 11967, USA
Tel: 1-631-624-4882 Fax: 1-631-938-8221
E-mail: [email protected]
www.creative-diagnostics.com
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