I can illustrate and describe the stages of DNA replica7on. How will I do this? I will create Cornell notes about DNA replica7on and prac7ce replica7on using a foldable. -­‐Before a cell divides, it copies its DNA in a copying process called replica(on. -­‐Why? To make iden7cal DNA DNA replica(on begins at a single point in the sequence and proceeds, in two direc7ons, un7l the en7re strand is replicated. This takes place in the nucleus. Where does DNA replica(on take place? Why must DNA be replicated? -­‐A number of different enzymes (helicase, DNA polymerase, DNA ligase, primase) are used to match both sides of the DNA ladder to new base pairs in a 5’ à 3’ direc7on -­‐Result? 2 NEW DNA molecules(each with 1 old/1 new strand) -­‐A special enzyme (helicase) is used to unzip the DNA molecule. -­‐DNA Polymerase binds bases to the new strand. -­‐Each strand of the DNA double helix has all of the informa7on needed to recreate the other half (base pairing rules). -­‐Because each strand can be used to make the other strand, the strands are said to be complementary. What does the word “complementary” mean when referring to DNA strands? Semi-­‐conserva(ve model: each strand aUer DNA replica7on is made from half the original(parent) strand and half new OLD The complementary strand for AGGCTAAGTCGGTA is TCCGATTCAGCCAT… Your turn… What is the complementary strand for the following: CGGAAT GCCTTA How does the structure of DNA make its replica(on easy? DNA Replica(on Foldable 1.  Now fold the two sides in to meet in the What you’re middle(hamburger style). given 2.  You have been given one side of the ORIGINAL/PARENT strand. Note: we have taken only one side of DNA from AFTER the replica7on fork. On the opposite side, draw and replicate the complementary strand. 3.  Open your edges, and complete the DNA word search. What you’re making STUDENT COPY I can illustrate and describe the stages of DNA replica7on. How will I do this? I will create Cornell notes about DNA replica7on and prac7ce replica7on using a foldable. DNA Replica7on
-­‐Before a cell divides, it ___________ its DNA in a copying process called replica(on. -­‐Why? To make __________DNA Name:____________________ DNA replica(on begins at a single point in the sequence and proceeds, in two direc7ons, un7l the en7re strand is replicated. This takes place in the . -­‐A number of different enzymes are used to match both sides of the DNA ladder to new base pairs -­‐Result?____NEW DNA molecules(each with 1 _____/1 _____ strand) -­‐A special enzyme is used to unzip the DNA molecule. -­‐Another enzyme, DNA __________ binds bases to the new strand. -­‐Each strand of the DNA double helix has all of the informa7on needed to recreate the other half (base pairing rules). -­‐Because each strand can be used to make the other strand, the strands are said to be ________________. ___________________ model: each strand aUer DNA replica7on is made from half the ___________(parent) strand and half _______ OLD The complementary strand for AGGCTAAGTCGGTA is TCCGATTCAGCCAT… Your turn… What is the complementary strand for the following: C G G A A T DNA Replica(on Foldable 1.  Now fold the two sides in to meet in the middle(hamburger style). 2.  Glue your word search on the back What you’re and let dry. given 3.  You have been given one side of the ORIGINAL/PARENT strand. Note: we have taken only one side of DNA from AFTER the replica7on fork. On the opposite side, draw and replicate the complementary strand. 4.  Open your edges. Follow my direc7ons for the inside. 5.  When 1-­‐4 are done, complete the ques7ons and THEN find the words on back. What you’re making BELL WORK: Label your paper 1-­‐7. Match the following with the correct part A. Adenine B. Base Pair C. Cytosine D. Deoxyribose sugar/Phosphate •  E. New Strand •  F. Replica7on Fork •  G. Nucleo7de • 
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