Material Safety Data Sheet
according to Directive 1907/2006/EC (REACh) and 453/2010/EU
Printing date: 10.05.2012
1
1.1
Date of issue: 10.05.2012
Page: 1/6
Identification of the Substance/Mixture and of the Company
Identification/Product Name
REF
Product name
730125
Chromab. columns Kombi-Kit PCB
25 x 500/500 mg Chromabond® SiOH-H2SO4/SA, PP
1.2
Use of the Substance/Mixture
Product for analytical use.
Exposure Scenario Classification according REACh, RIP 3.2 Codes: SU 0-2, PC 21, PROC 15, AC 0
1.3
Manufacturer
MACHEREY-NAGEL GmbH & Co. KG
Neumann-Neander-Str. 6-8, 52355 Dueren, GERMANY
Tel.: +49 2421 969 0
1.4
E-mail: [email protected]
Emergency Telephone
Outside Germany (DE):
Call your regional Poisons Information Service or call local Life Saving Service.
DE: Gemeinsames Giftinformationszentrum (GGIZ)
99089 Erfurt tel. +49 361 730 730
2
2.1
Hazard Identification
Hazard Symbols of Product
Directive 1999/45/EC
Symbols
R
C
R 35
GHS Directive 1272/2008/EC
GHS Symbols
GHS05
2.2
Signalword
DANGER
Hazard identification
Hazard classes/categories
H314
Skin Corr. 1A
Hazard Description
Possible Hazards from physicochemical Properties
Generally in the case of pH values are less than 2 or higher than 11.5 then it is corrosive.
Information pertaining to particular Risks to Human and possible Symptoms
Causes varying degrees of acid burns on the skin, to the eyes and to the mucous membranes and wounds which do not heal
quickly depending on the concentration, temperature and the exposure time. Vapours especially which steam from hot liquids and
mist can have a severe irritant effect upon the eyes and the respiratory organs.
Information pertaining to particular Risks to the Environment
Avoid contact of chemical/mixture to environment.
Other Hazards
2.3
Hazard description of the components
500/500 mg Chromabond® SiOH-H2SO4/SA, PP
Version: 0.7
Material Safety Data Sheet
according to Directive 1907/2006/EC (REACh) and 453/2010/EU
Printing date: 10.05.2012
Date of issue: 10.05.2012
Page: 2/6
Directive 1999/45/EC
R 35
Symbols
C
GHS Directive 1272/2008/EC
GHS Symbols
GHS05
Signalword
3
3.1
DANGER
Hazard identification
Hazard classes/categories
H314
Skin Corr. 1A
Composition/Information on Ingredients
Hazardous Components
500/500 mg Chromabond® SiOH-H2SO4/SA, PP
Chemical:
silica
Concentration:
20 - 80 %
Formula:
SiO2
REACH Reg. No.:
112926-00-8
EC No.:
231-545-4
RTECS:
VV7315000
TSCA listed:
listed
acc. 1999/45/EC:
Chemical:
sulphuric acid
Concentration:
30 - 51 %
Formula:
H2 SO4
REACH Reg. No.:
01-2119458838-20
EC No.:
231-639-5
RTECS:
WS5600000
TSCA listed:
listed
acc. 1999/45/EC:
R 35
3.2
CAS No.: 7631-86-9
MFCD:
MFCD00011232
acc. CLP (GHS):
not necessary
CAS No.: 7664-93-9
Indice No.:
016-020-00-8
acc. CLP (GHS):
H314
Remarks
List of R and H phrases: see chapter 16
4
4.1
First Aid Measures
General Information
Place insured person out of danger zone to fresh air immediately. Ensure quiet, warmth, and provide resuscitation if necessary. If
necessary contact medical advice. Remove contaminated clothing. Show product package, packing insert and this material safety data
sheet to the doctor.
Version: 0.7
4.1.1
After SKIN Contact
Remove contaminated clothing immediately. Rinse the affected skin or mucous membrane thoroughly for min. 15 minutes under
running water. Avoid neutralisation. Then apply a loose bandage.
4.1.2
After EYE Contact
After contact with the eyes rinse thoroughly under running water with the eyelid wide open for min. 10 minutes with eye washing
bottle, eye douche or running water (protect intact eye). Before (if possible) apply eye drops Proxymetacaine 0.5%, if the opening
the eyelid convulsion is painful. Further treatment to be carried out by an eye specialist.
4.1.3
After INHALATION of Vapours
If vomiting and if insensible place patient in recovery position and keep airways free.
4.1.4
After ORAL Intake
After oral intake lots of water with activated charcoal supplement should be drunk after it has been ingested. Do not induce vomiting
under any circumstances. Do not make any efforts to neutralise it. Contact medical advice for possible consequences.
Material Safety Data Sheet
according to Directive 1907/2006/EC (REACh) and 453/2010/EU
Printing date: 10.05.2012
4.2
Date of issue: 10.05.2012
Page: 3/6
Further Medical Treatment/Attention
CORROSIVE DAMAGE: After SKIN CONTACT rinse with water for a long time. Efforts to neutralise the substance can frequently make
matters worse. Apply glucocorticosteroides following inflammatory reactions. After EYE CONTACT rinse immediately with plenty of
water for a long time. Eyelid convulsion measures. Name the corrosive chemical. Further treatment must to be carried out by an eye
specialist. After INTAKE administer aluminium oxide drug suspensions. Administer a prophylaxis to counter pulmonary oedema
following the INGESTION of corrosive aerosols. In the event of RESPIRATORY DISTREES ensure that the patient inhales oxygen.
5
5.1
Fire-fighting Measures
Suitable Extinguishing Media
Fire extinguishers appropriate to the fire classification, and, if applicable, a fire blanket must be available in a prominent location in the
work area. All extinguishers like FOAM, WATER SPRAY, DRY POWDER, CARBON DIOXIDE can be used.
5.2
Hazards, Combustion Products/Gases
Danger for environment only in the event of a large-scale leakage or formation of hazardous substances.
5.3
Special Protective Equipment required
If necessary protective breathing apparatus which is independent of the ambient air (isolated equipment), and sealed protective clothing
is necessary in the event of a large-scale formation of toxic substances.
5.4
Additional Information
Product package burns like paper or plastic.
6
6.1
Accidental Release Measures
Personal Precautions
Wear suitable protective gloves (see 8.2.2). Wear eye protection, respectively face protection. Regular staff training is necessary,
indicating hazards and precautions on the basis of operating instructions. Restrictions on activity must be observed.
6.2
Methods of Cleaning-up
And dispose in accordance to local regulations for the disposal of hazardous chemicals. Clean any contaminated equipment and floors
with plenty of water.
7
Handling and Storage
7.1
Handling
7.2
Storage
The original product package of MACHEREY-NAGEL allows a safe storage.
Storage class (German chemical industry): see chapter 12.1
7.2.1
8
8.1
Requirements for Stock Rooms and Containers
Keep original product packages tightly closed during handling and storage. Use inbreakable container for transport of glass bottles.
Exposure Controls/Personal Protection
Exposure Limit Values
500/500 mg Chromabond® SiOH-H2SO4/SA, PP
Chemical:
silica
TRGS 900 (DE):
Staub 4 E mg/m³
TRGS 901 (DE):
No. 96
SUVA(CH) MAK value:
4 e mg/m³
TRGS 905 (DE):
RF C
Chemical:
sulphuric acid
TRGS 900 (DE):
Short-term exposure factor:
TRGS 901 (DE):
SUVA(CH) MAK value:
TRGS 905 (DE):
Version: 0.7
CAS No.: 7631-86-9
CAS No.: 7664-93-9
0.1 E mg/m³
1 (I)
104
0,1 e mg/m³
RF C
Material Safety Data Sheet
according to Directive 1907/2006/EC (REACh) and 453/2010/EU
Printing date: 10.05.2012
8.2
Date of issue: 10.05.2012
Page: 4/6
Exposure Controls
The highest level of cleanliness must be maintained at the workplace.
8.2.1
Respiratory Protection
Only if additional recommendations in test instruction or packing insert. Use for regulary working with dry powders a dust mask or a
dust protection filter, class P3.
8.2.2
Hand Protection
Yes, gloves according EN 374, consist of natural latex, butylrubber, viton or nitril (f.ex. Neopren® or Camatril from KCl). Use for
short times all chemical resistent gloves (limited).
8.2.3
Eye Protection
Yes, safety glasses according EN 166 or face protection.
8.2.4
Skin Protection
Recommended, to avoid clothing damage, to avoid contamination with these hazards.
8.2.5
Personal Hygiene
Eating, drinking, smoking, taking snuff and storage of food in work areas and at outdoor workplaces is prohibited. Avoid contact
with the skin, eyes and clothing. Rinse any clothing on which the substance has been spilled, and soak it in water. Wash hands
thoroughly with soap and water when stopping work and before eating, and then apply protective skin cream.
9
9.1
Physical and Chemical Properties
General Information
500/500 mg Chromabond® SiOH-H2SO4/SA, PP
Color: colourless
Odor: odorless
9.2
9.2.1
Appearance: solid
Important Health, Safety and Environmental Information
Safety relevant Basis Data
500/500 mg Chromabond® SiOH-H2SO4/SA, PP
pH:
0-1
9.2.2
9.3
Relevant Properties of Substance Group
Additional Information
10 Stability and Reactivity
10.1
Conditions to avoid
If on label.
10.2
Materials to avoid
10.3
Hazardous Decomposition Products
Avoid contact with strong acides or alkalines.
In the original package all parts are safety stored. Decompositions are not observed during the expiration period under recommended
conditions.
11 Toxicological Information
Following information is valid for pure chemicals.
500/500 mg Chromabond® SiOH-H2SO4/SA, PP
Version: 0.7
Chemical:
LD50orl rat :
silica
>>2000 mg/kg
CAS No.: 7631-86-9
Chemical:
LD50orl rat :
LC50ihl mouse :
LC50ihl rat :
sulphuric acid
2140 mg/kg
3204h mg/L
510 mg/m³
CAS No.: 7664-93-9
Material Safety Data Sheet
according to Directive 1907/2006/EC (REACh) and 453/2010/EU
Printing date: 10.05.2012
Date of issue: 10.05.2012
Page: 5/6
12 Ecological Information
12.1
Ecotoxicity
Following information is valid for pure chemicals.
500/500 mg Chromabond® SiOH-H2SO4/SA, PP
Chemical:
silica
WGK (DE):
nwg
WGK No.: 0849
storage class (VCI): 13
Chemical:
sulphuric acid
LC50fish/96h :
16-29 mg/L
EC50daphnia/48h :
2924h mg/L
WGK (DE):
1
WGK No.: 0182
storage class (VCI): 8 B
CAS No.: 7631-86-9
CAS No.: 7664-93-9
13 Disposal Considerations
Please observe local regulations for collection and disposal of hazardous waste and contact waste disposal company, where you will obtain
information on laboratory waste disposal (waste code number 16 05 06).
Dispose of contents/container to regulated waste treatment.
14 Transport Information
Class 8 II, excepted quantities (≤30 mL/∑≤500 mL) = ADR/ IATA E2
15 Regulatory Information
15.1
International Regulations
500/500 mg Chromabond® SiOH-H2SO4/SA, PP
Directive 1999/45/EC
Symbols:
C
R 35
Causes severe burns.
S 22-26
Do not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
GHS Directive 1272/2008/EC
GHS Symbols:
GHS05
Signalword: DANGER
H314
Causes severe skin burns and eye damage.
P260D, P280sh, P301+330+331, P303+361+353, P304+340, P305+351+338
Do not breathe vapours. Wear protective gloves/eye protection. IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED:
Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for
several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Version: 0.7
Material Safety Data Sheet
according to Directive 1907/2006/EC (REACh) and 453/2010/EU
Printing date: 10.05.2012
15.2
Date of issue: 10.05.2012
Page: 6/6
National Regulations
German act governing protection from hazardous substances (Chemicals Act / Chemikaliengesetz- ChemG), revised on May 2008
German order governing protection from hazardous substances (Ordinance on Hazardous Substances / Gefahrstoffverordnung GefStoffV), revised on November 2010, according to Directive 98/24/EC
TRGS 200, German engineering rules governing the classification and labelling of hazardous substances, preparations and products,
updated October 2011
Announcement BekGS 220 (DE), Safety Data Sheet, February 2011
16 Other Information
16.1
List of R and H phrases
16.1.1
List of relevant R phrases
R35
Causes severe burns.
16.1.2
List of relevant H phrases
H314
Causes severe skin burns and eye damage.
16.2
Training Advice
Multiple safety training of staffs about danger and protection by using hazards in working area. Additionally training and introduction of
staffs for using these products.
16.3
Recommended Restriction on Use
Only for professional user.
Look about employee restrictions for young people (f. ex. DE § 22 JArbSchG)!
Look about employee restrictions for pregnant women and nursing women (f.ex. DE §§ 4 und 5 MuSchRiV)!
An individual package of this product or test kit has a moderate hazardous potential.
16.4
Further Information
MACHEREY-NAGEL GmbH & Co. KG provides the information contained herein in good faith being up-to-date of own realizations at
revision time. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained
person using this product. Individuals receiving the information must exercise their independent judgement in determining its
appropriateness for a particular purpose.
MACHEREY-NAGEL GmbH & Co. KG makes NO REPRESENTATIONS or WARRANTIES, either expressed or implied, including
without limitation any warranties of merchantability, fitness for a particular purpose with respect to the information set forth herein or the
product to which the information refers. Accordingly MACHEREY-NAGEL GmbH & Co. KG will not be responsible for damages resulting
from use of or reliance upon this information. See terms and conditions at the end of our price lists for additional information.
16.5
Sources of Key Data
Regulation 453/2010/EU REACH - REQUIREMENTS FOR THE COMPILATION OF SAFETY DATA SHEETS
TRGS 900, German engineering rules governing limits in air at work, updated May 2010
SUVA .CH, Limits in air at work 2009, revised on 01.2009
KÜHN, BIRETT
Merkblätter Gefährliche Arbeitsstoffe (Data Sheets of Hazardous Substances)
You find our current versions of MSDS in Internet:
http://www.mn-net.com/MSDS
Version: 0.7