§ § § § § § § § § § § § § § § § § § § § § § § § § § § § § § Intro Knowthesevencharacteristicsoflivingorganisms. Knowthedomainsandkingdoms.Whatareineachofthedomainsand kingdoms? Knowthestepsofthescientificmethodandbeabletodescribethestepsin order. Beabletoidentifyahypothesis,variable,testgroup,controlgroup,and constants. Knowthephasesofclinicaltrials. Chemistry Knowthethreeparticlesofanatom,wherearetheylocated,aswellasthe charge,andmassofeachparticle. Beabletodeterminehowmanybondseachelementcanform. Beabletorecognizeifamoleculeisdrawncorrectly. Beabletodeterminethenumberofprotons,neutronsandelectronsinthe atomsofallthebiologicallyimportantelementsusingtheperiodictable. Knowthethreemostcommonelementsinthehumanbody. Beabletoidentifypolarandnonpolarmolecules. Knowthetypesofchemicalbondsandhowtheyareformed. Beabletodescribethefourpropertiesofwaterandtheirimportancein livingorganisms. UnderstandthepHscale. Knowthethreemostcommonelectronegativeelementsfoundinbiological molecules. BiologicalMolecules Knowthefunctionsofeachofthebiologicalmolecules. Knowthetypesofcarbohydrates,wheretheyarefound,thefunction(s)of each,andthedigestibilityofeach. Knowinwhatpartsofthebodyglycogenismainlystored. Knowthecauseandsymptomsoflactoseintolerance. Knowthemonomerunitofcomplexcarbohydrates. Knowthebasicstructureofthecomplexcarbohydrates(branched,tightly packedandstabilizedbyH-bonds,etc,coiled). Knowthedifferenttypesoflipids,theirfunctions,theirbasicstructures,and themoleculesthatmakeupeachlipid. Knowthedifferenttypesoffattyacids,andtheorderfromhealthiesttoleast healthy. Knowthepropertiesofphospholipids. Knowthefunctionsofeachtypeoflipid. Knowthemonomerunitofproteinsandwhattypeofbondjoinsthem together. Knowtheprimary,secondary,tertiary,andquaternarystructureofaprotein. Knowthefunctionsofproteins. Knowthemonomerunitsthatmakeupnucleicacids.Knowthegeneral structureofnucleotides.Knowthemoleculesthatformnucleotides. Beabletoidentifyfromapictureanyofthebiologicalmolecules. § § § § § § § § § § § § § § § § § § § § § § § § § § § § § § WhatarethedifferencesbetweenRNAandDNA? WhatarethefunctionsofDNAandRNA? TheCell Knowwhymostcellsaresmall. Knowthemaindifferencesbetweenprokaryoticcellsandeukaryoticcells, andknowexamplesofprokaryoticcellsandeukaryoticcells. Knowthemajorfeaturesofcellsandtheirfunction: § Plasmamembrane,Cytoplasm,Nucleus,Cytoskeleton,Mitochondria, Ribosomes,Endoplasmicreticulum(smoothandrough),Golgibody, Vesicles,Lysosomes Knowwhatdisorderisassociatedwithamissingenzymeinlysosomes. Knowthetypesofcytoskeletonandtheirfunctions. Knowwhatcytoskeletonmakesupciliaandflagella Functionsoftheplasmamembrane Knowthemaincomponentsoftheplasmamembraneandthefunctionof eachcomponent. Knowwhatcanandcan’tpassfreelythroughamembrane. Knowthedifferencesbetweenpassivediffusion,facilitateddiffusion,and activetransport. Knowhowthingsaretransportedinandoutofacellusingavesicle. DNA/ProteinProduction KnowthestructureofDNA. Knowwhatmoleculesarebondedtogetherandinwhatorder. Knowwhattypeofbondsholdsthesubunitstogether. Knowthefourbasesandwhichbasesarepairedtogether. KnowthestepsofDNAreplication. KnowwhereDNAreplicationtakesplace. KnowtheroleofhelicaseandDNApolymerase. KnowwhatsuppliestheenergytobuildthenewstrandofDNA. Knowwhatmutationsare,whatpointmutationsare,possibleoutcomesof mutations. KnowthestructuraldifferencesandsimilaritiesbetweenDNAandRNA. BeabletodeterminethecomplementarymRNAsequencefromaDNA sequence. Knowthestepsofproteinsynthesis. Knowwhattranscriptionandtranslationareandthestepsinvolvedineach. Beableto“read”mRNAtomakeaprotein,giventhetableofcodonstoamino acids. KnowthetypesofRNA,theirfunctions,andwhereinthecelltheyfunction. CellularMetabolism Knowwhatcellularrespirationandanaerobicfermentationareandthe differencesbetweenthem. Knowthefourstepsofaerobiccellularrespiration,whathappensineach step,whatarethestartingmolecules,whatcomesoutofeachstep,wherein thecelldoeseachstepoccur,howmanyATPandNADH/FADH2areproduced ineachstep. § § § § § § § § § § § § § § § § § § § § § § § § § § § § § § § § DescribeindetailhowATPismadeusingtheelectrontransportchainand ATP-synthase KnowtheroleofATP-synthase,H+,O2,NADHandFADH2andtheelectron transportchaininATPproduction. IntrotoA&P/IntegumentarySystem Knowthe4tissuetypes,theirfunctions,andexamplesofeachtype. Knowwhatcellsmakeupeachtypeoftissue. Knowwhyittakesalongtimeforcartilagetoheal. Knowhownegativeandpositivefeedbackwork,beabletodescribethe examplesofnegativeandpositivefeedbackgiveninclass,andbeableto identifythesensor,controlcenter,andeffectorforeachexample. Knowthethreecell-celljunctionsandtheirfunctions. Knowthebodycavities,theirlocationandwhateachcavitycontains. Knowthefourtypesofmembranes,theirfunctionsandlocations. Knowthefunctionsoftheintegumentarysystem. Knowthecomponentsoftheintegumentarysystemandtheirfunctions. Knowthetwolayersoftheskin,thetypeoftissuesthatcompriseeachlayer, andwherearethelayerslocated. Knowwhatlayerliesunderneaththeskin,andwhattissuetypemakesup thislayer. Knowthethreetypesofskincancer. Knowwhatmelanocytesare,andtheirfunction. SkeletalSystem Knowthefourcomponentsoftheskeletalsystem,andtheirfunctions. Knowthefunctionsofbone Knowthepartsofatypicallongbone. Knowthestructuralunitofcompactbone,andknowthefeaturesfoundin theosteon. Knowthethreetypesofbonecellsandtheirfunctions. Knowthepartsofsynovialjointsandtheirfunctions. Knowthehormonesinvolvedinbonegrowthandhomeostasis;whatglands producecalcitoninandparathyroidhormones. Knowthedisordersoftheskeletalsystem. Knowhowbonesheal. Knowwhatosteoporosisisandtheriskfactorsforosteoporosis,andwhat canbedonetopreventit. NervousSystem Knowthefunctionsofnervoussystem. Knowthethreetypesofneuroglialcellsandtheirfunctions. Knowthetwomaindivisionsofnervoussystem(CNS,PNS)andwhereeach isfound. Knowthepartsandfunctionsofaneuron. Knowthethreetypesofneurons(sensory,interneuronandmotorneurons), theirfunctions,andwherearetheylocated. Knowwherethecellbodiesarelocatedforthetreetypesofneurons. Knowwhatschwanncellsandoligodendrocytesareandtheirfunction. § § § § § § § § § § § § § § § § § § § § § § § § § § § § § § Knowthecauseandeffectsofmultiplesclerosis Knowthepartsofanerve Knowthefunctionofthesodiumpotassiumpump Knowthestepsofanactionpotentialbeingconductedthroughaneuron, startingwiththerestingstageandendingwiththenextneuronormuscle beingstimulated. Knowthecomponentsofthesynapse. Knowthefunctionofneurotransmitters,howtheywork,andwherethey work. Knowwhatacetylcholineis,whereitisfound,whateffectithas,andhowitis removedfromthesynapticcleft. KnowthecauseandeffectofMyastheniagravis. Knowwhatthesomaticnervoussystemandautonomicnervoussystemare, andwhattheycontrol. Knowwhatreflexactionsare. KnowwhattheParasympatheticdivisionandtheSympatheticdivisionare, andwhatspecificallytheycontrol. KnowwhatprotectstheCNS. Knowwhatthethreelayersofthemeningesare,andtheirlocation(whichis theinner,middleorouterlayer). Knowwhatmeningitisis,andwhatcausesit,andknowwhatencephalitisis. Knowthefunctionsofcerebrospinalfluid. Knowthefunctionoftheblood-brainbarrier,andwhatitallowstopass. Knowthemajorregionsofthebrainandtheirfunctions. Knowwhatthecorpuscallosumisanditsfunction. Knowthefunctionofsensoryreceptorcells. Knowthetypesofsensoryreceptorsinskin,andwhattypeoftouchthey detect. Knowallofthelayersandstructures(includingthefluids)oftheeyeand theirfunctions. Knowwhattheblindspotis. MuscularSystem Knowthefunctionsofskeletal,cardiacandsmoothmuscles. Knowhowskeletalmusclesworkinpairs. Knowthestructureandthecomponentsofamuscle. Knowthestructureandcomponentsofamusclecell(musclefiber)andthe functionsofthecomponents. Knowwhatstimulatesamuscletocontract. Beabletodescribethestepsofhowthemessageistransmittedfromthe neurontothemyofilamentsandwhathappenswhenthesignalreachesthe myofilaments Knowthethreeenergysourcesformusclecontraction,andwhichrequire oxygen,whichproducecarbondioxide,howmanyATPareproducedbyeach, andhowlongeachcanprovideenergy. EndocrineSystem Knowthefunctionoftheendocrinesystem. § § § § § § § § § § § § § § § § § § § § § § § § § § § § § Knowthesimilaritiesanddifferencesbetweenneurotransmittersand hormones. Knowthetwotypesofhormones;howeachtypeofhormoneworks,how doeseachaffectitstargetcells. Knowwhereallthehormonesfromlectureareproducedandreleased,and whatthefunctionsofthehormonesare,andwhatthetargetofeachhormone is. Knowhoweachglandiscontrolled. Knowallofthedisordersdiscussedinthelecture,andwhatthecauses, effects,andtreatmentsofthedisordersare. Knowhowthehypothalamuscontrolsthepituitarygland. Knowhowcalciumlevelsinthebloodareregulated,andwhathormonesand glandsregulateit. Knowhowbloodglucoselevelsareregulated,andwhathormonesand glandsregulateit,knowthecausesofthetwotypesofdiabetes. Blood Knowwhattypeoftissuebloodis. Knowthecompositionofblood,plasma,andformedelements. Knowthefunctionsofblood. Knowtheexamplesofproteinsfoundinblood,andwhatthefunctionsof thesebloodproteinsare. Knowwherebloodcellsareformed. Knowhowwhitebloodcellsleavethebloodvesselsandentertissues. Knowthecharacteristics,andfunctionsofRedBloodCells,WhiteBloodCells, andPlatelets. Knowthetypesofwhitebloodcellsandtheirfunctions. Beabletodescribethestepsofhowabloodclotisformedandremoved. Knowwhatvitaminisnecessaryforclottingtooccur. Knowwhatcommondruginhibitsclotting. Knowthemajorbloodtypes,andwhatantibodiestheyhave. Knowwhichbloodtypescandonatetoeachother,andtheuniversaldonor, andtheuniversalrecipient. KnowwhattheRhfactoris,andwhatproblemsitcancauseinpregnancyand blooddonation. Knowtheresultofareactiontoaforeignbloodtypeantigen. Knowalltheblooddisordersdiscussedinclass. Genetics X-LinkedInheritance–knowhowtraitsarepassedtooffspringontheX chromosome,andwhymalesaremorelikelytobeaffected. Autosomaldisorders–knowthedifferencesbetweenrecessiveand dominantautosomaldisorders. Knowthebenefitsofsicklecellanemia. Dominantautosomaldisorder–Huntingtonsdisease.Knowthegeneralage ofonsetofHuntingtonandhowitaffectspassingonthetrait. Knowthebasicsofhowaneuploidycanhappenandthatitcanhappenduring MeiosisIorII. § § § § § § § § § § § § § § § § § § § § § § § § § § § § KnowthatDownssyndromeisanexampleofAneuploidy. KnowthatCri-du-chatsyndromeisanexampleofchangestochromosomal structureduetodeletionofpartofthechromosome. CardiovascularSystem Knowthefunctionsandcomponentsofthecirculatorysystem. Knowthecomponentsofthebloodvesselandtheirfunctions,andwhata crosssectionofavein,arteryandcapillarylooklike. Knowthepathofthebloodthroughthebody,startingwithwhenitleaves theheartthroughtheaorta,intoarteries,thenarterioles,thencapillaries, thenvenules,totheveins,tothevenacava,backtotheheart. Knowhowarteriolesaffectbloodpressure. Knowthepressuresthatcausefluidtoenterandleavethecapillariesand whatpressurecausesgassestoenterandleavethecapillaries.Beableto discussindetailthetransportoffluid,gasses,nutrientsandwasteacrossthe capillaries. Knowthefunctionofcapillaries. Knowthechambersoftheheart,andwhicharethelowerchambersand whicharethemoremuscularchambers. Knowthepathofthebloodthroughtheheart. Beabletodescribethecardiaccycle. Knowhowtheheartbeatisregulated,bothintrinsicallyandextrinsically. KnowthethreewavesontheECGandbeabletodescribetheeventsthat happenduringeachofthewaves. Knowwhatcausesbloodtoflowinthearteriesandintheveins. Knowwhatthepulmonary,systemicrenal,hepaticportal,andcoronary circuitsare,andwhattissuestotheygoto. Knowthecausesandeffectsofthecardiovasculardiseasesdiscussedin lecture. Knowthetwotreatmentsofcoronaryarteryblockage. Knowthefunctionofthelymphaticsystem. Knowthecomponentsofthelymphaticsystemandtheirfunctions. Knowwhatlactealsareandtheirfunction. Knowwhatcausesfluidstotravelthroughlymphaticvessels. ImmuneSystem&Disease Knowtheexamplesofbarrierdefenses. KnowwhattheNonspecificdefensesandtheSpecificdefensesare,andthe differencesbetweenthetwo. Knowthethreetypesoflymphocytes,whicharepartofthespecificand whicharepartofthenonspecificdefensesystem. Knowhowthebodymountsaninflammatoryresponseandwhattheeffectis onthebody. Knowthefunctionsofcomplementproteinsandinterferons. Knowthefunctionofmajorhistocompatibilitycomplex(MHC)markers. KnowwhereTcellsandBcellsareproduced,wheretheymature,wherethey arefoundoncetheyhavematured,andwhethertheyarepartofthecell mediatedorantibodymediateddefenses. § § § § § § § § § § § § § § § § § § § § § § § § § § § § § § § § § § § § KnowthetypesandfunctionsofTcells. Knowwhatantibodiesare,howtheyareproduced,andtheirfunctions. Knowwhatmemorycellsare,whatplasmacellsare,andhowclonalselection works. Knowwhat“antigen-presentingcells”(APCs)areandtheirfunction. KnowthetargetofHIV. KnowhowdoesHIVreplicateitself(includingtheenzymesneeded). Knowexamplesofautoimmuneandimmunesystemdiseases,thetargetof theautoimmunediseases. Knowwhattheeffectofallergiesonthebodyis. Knowtheshapesofbacteria(latinnames). Knowhowbacteriacausedisease. Knowexamplesofpathogenic(bad)bacteria. Knowexamplesofbeneficial(good)bacteria. Beabletodiscussantibioticresistance,includingthecausesandeffects. Knowhowtodesignanantibiotic,whattargetwouldyouuse. Knowthecharacteristicsofviruses. Knowthestepsofviralreplication. KnowhowtodesignanHIVdrug;includingwhattargetsyouwouldattack. RespiratorySystem Knowthefunctionoftherespiratorysystem. Knowthelocationandfunctionoftheallthepartsoftherespiratorysystem. Knowwhichcelltypelinesthetrachea,whatareitsfunctions. Knowwheretheexchangeofgasesoccursinthelungs. Knowwhatcontrolstherateofbreathing. Beabletodiscussthemechanicsofbreathing. Knowhowoxygeniscarriedintheblood. Knowhowcarbondioxideiscarriedintheblood,knowalltheways,and whichwayisthepredominateway. Beabletodiscussthedisordersoftherespiratorysystemincludingthe description,symptoms,causes,andtreatments. DigestiveSystem Knowthefunctionsofthedigestivesystem. KnowthelayersoftheGItractandbeabletodescribethelayersandwhat thefunctionsofthelayersare. Knowthepartsofthemouthandtheirfunctions. Knowthemajorpartsofthedigestivesystemandtheirfunctions. Knowhowfoodisabsorbedinthesmallintestine. Knowhowarefatsabsorbedversusothernutrients. Knowwhatthestructureofvilliis,andtheroleofbloodcapillariesand lacteals.Knowtheroleofbileandlipaseinfatdigestion. KnowwhattypeofmuscleisfoundinthewalloftheGItract,howmany layersareinthestomachandtheintherestoftheGItract. Knowthefunctionofthemuscles. Knowwhatpancreaticsecretionscontain,andtheirfunctions. § § § § § § § § § § § § § § § § § § § § § § § § § Knowthedigestiveenzymes,andchemicalsecretions(bileandacid)their specificfunctions,andwheretheyaresecretedfromandtheirsiteofaction. Knowthefunctionoftheacidsecretedinthestomach. Knowthefunctionofglobletcells. Beabletodescribeallthedisordersofthedigestivesystem,includingthe causes,effectsandtreatments. UrinarySystemandExcretion Knowthefunctionsoftheurinarysystem. Knowwhatcompoundsarecontainedinurine,andwhatcompoundsarenot containednormallyinurine. Knowtheorgansoftheurinarysystemandtheirfunctions,includingallthe functionsofthekidney. Knowthebloodvesselsthatleadtoandfromthekidneyandthevessels withinthekidney. Knowthethreeregionsofthekidney. Knowthefunctionofanephron,thepartsofthenephron,andthefunctions oftheseparts. Knowwhatglomerularfiltrationis,whatreabsorptionandsecretioninthe nephronare,andwhatiscontainedinthefiltrateleavingtherenalcorpuscle. Knowhowisurinaryoutputisregulated,andexamplesofdiuretics. Knowwhichhormonesdecreaseorincreaseurinaryoutput,knowtheeffect onthenephronandbloodpressurethesehormoneshave,wherethese hormonesareproduced,storedandreleased. Knowthefunctionofrenin,whereitisproduced,whatitstargetisandwhat theeffectofreninonurineproductionandbloodpressureis. KnowtheroleofthekidneyinVitDproductionandcalciumabsorption,and theactiveformofVitD? KnowhowthekidneyregulatesbloodpHandmaintainsosmoticbalance. Knowhowtheregulationofsalt/waterbalanceaffectsbloodpressure. Beabletodiscussthedisordersoftheurinarysystem,includingthecauses, effectsandtreatments. HumanReproduction Knowtheorgans,theirlocationandthefunctionsofthemalereproductive system,includingglands. Knowwhichcellsinthetestessecretetestosterone. Knowhowspermareformed,whereformationtakesplace,thepathofthe spermastheyleavethebody,andtheimportantcomponentsofasperm. Knowhowmalereproductionisregulated,whathormonesareinvolvedin malereproduction,wheretheyareproduced,whattheirtargetisandwhat theirfunctionis.Knowhowthesehormonesareregulated,andbeableto discussthisindetail. Knowallthepartsandorgansofthefemalereproductivesystem,their functionandlocation. Knowhowaneggdevelops,wheretheoocyteisfertilized,andwhenand whereafertilizedeggimplants. Knowtheoverviewoftheovariananduterinecycles(verygenerally). § § § Knowthehormonesthatareimportantinfemalereproductionandtheir functions. KnowhowRU-486andprevenwork,andwhichwillcausethelossofan implantedembryo. BeabletodiscussthedisordersofthereproductivesystemandSTDs, includingcauses,detectionandtreatment.
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