JobOffer
PostdoctoralScientist
ProteinBiochemistryandsmallmoleculescreening
We are seeking a Postdoctoral Research Fellow with excellent expertise in protein
biochemistry and solid proficiency in cellular biology techniques. Experience with
protein-RNA interactions, assay development and the screening of small molecule
libraries are desired. The successful candidate will focus on the characterization of
protein-RNA association and the development of high-throughput assays for the analysis
of small molecule inhibitors interfering with the expression or RNA-association of
oncogenic RNA-binding proteins (RBPs).
Weexpect:
• Strongoralandcommunicationskills(English)
• Theabilitytoworkindependentlybutaspartofanenthusiasticresearchteam
• AstrongtrackrecordinthefieldofProteinBiochemistrywithexpertiseinthe
purificationofrecombinantproteins,characterizationofprotein-ligandassociation
(preferablyproteinnucleicacidinteractions)andanalysisofproteinstructurebyNMR
• Solidexpertiseinbasiccellbiologytechniques
• Expertiseinthedevelopmentofhighthroughputassaysisdesired
The Hüttelmaier lab:
Our major research focus is the analysis of RBPs and non-coding RNAs in cancer. In
previous work, we characterized RBPs with significant oncogenic potential in various
solid cancers. Recently, we identified small molecule drugs targeting the expression of
these RBPs as well as some of their downstream effectors in cancer cells. The ultimate
goal of the research project supported by EU funds is the identification of small
molecules drugs targeting the expression of RBPs or their RNA-association in cancerderived cells.
Educationandworkexperience:
• Ph.D.inbiology,biochemistry,biotechnologyorcellbiology
• Threeyearsofspecifiedexperienceinproteinbiochemistry
Howtoapply:
PleasesendyourCValongwithdocumentstostefan.huettelmaier@medizin.uni-halle.de