Document Title: Sodium Azide with Cab-O-Sil Safety Data Sheet
SAFETY DATA SHEET
1. IDENTIFICATION
Product Identifier:
Synonyms:
Product Code:
Sodium Azide with Cab-O-Sil
Azide
Reach Registration 01-2119457019-37-0002
Registered as a “Transported Isolated Intermediate”
SDS compliant with regulations: (EC) No 1907/2006 (REACH), (EC) No 1272/2008 (CLP)
Manufacturer / Supplier:
American Pacific
Address:
10622 West 6400 North, Cedar City, UT 84721
Telephone:
+1 (435) 865-5000
Fax:+1 (435)-865-5005
Emergency Contact:
CHEMTREC
Customer Number: CCN721187
US Tel: 1 (800) 424-9300
Int'l Tel: +1 (703) 741-5970
Use of the substance/restrictions: Analytical chemistry, automotive airbags and other nitrogen gas generator
functions, pharmaceutical and chemical intermediate, preservative, proposed use as an active ingredient in broad
spectrum agricultural pesticides.
Do not expose sodium azide to heavy metals whereas heavy metals azides are instable. Do not combine sodium
azide with low-pH liquids and vapors, since hydrazoic acid may form.
2. HAZARDS IDENTIFICATION
Hazard Classification:
Acute toxicity, Oral (Category 2), H300
Acute toxicity, Dermal (Category 1), H310
Specific target organ toxicity - repeated exposure, Oral (Category 2), Brain, H373
Acute aquatic toxicity (Category 1), H400
Chronic aquatic toxicity (Category 1), H410
Signal Word: Danger
Preparation classification:
This substance is defined as a “Transported Isolated Intermediate” (Article 3(15) of REACH) and should be used
under “Strictly Controlled Conditions” (Article 18(4)) for Intermediates under REACH.
Physical Hazard:
All - Conclusive but not sufficient for Physical classification
Health Hazard:
H300 + 310
H410:
H400:
EUH032:
H373:
Fatal if swallowed
Very toxic to aquatic life with long lasting effects
Very toxic to aquatic life
Contact with acids liberates very toxic gas
May cause damage to the brain through prolonged or repeated exposure
Precautionary Statements:
P264
Wash skin thoroughly after handling
P270
Do not eat, drink or smoke when using this product
P273
Avoid release to the environment
P280
Wear protective gloves/ protective clothing/ eye protection/ face protection
If on skin wash with plenty of water
P402
Store in a dry place
P404
Store in a closed container
P505
Dispose of contents/ container to an approved waste disposal plant
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Effective Revision Date: 25 May 2016
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Document Title: Sodium Azide with Cab-O-Sil Safety Data Sheet
Additional Labeling Requirements: EUH032: Contact with acids liberates very toxic gas.
Emergency overview: Sodium Azide is an odorless white crystal material. Sodium Azide can lower blood
pressure and cause headaches, shortness of breath, faintness, loss of consciousness, increased heart rate, and
respiration. Sodium Azide is a poison and may be fatal if large doses are ingested. Routes of exposure are;
inhalation, ingestion, and absorption through the skin and eyes.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Ingredient Name
Sodium Azide
Chemical Makeup
CAS#
NaN3
26628-22-8 247-852-1
EC#
Cab-O-Sil/Silica
O2Si
262-373-8
7631-86-9
% NH3
~100%
0.1 – 0.6%
4. FIRST AID MEASURES
If breathing is irregular or stopped, administer artificial respiration.No artificial respiration, mouth-to-mouth or
mouth-to-nose. Use suitable instruments/apparatus.Symptomatic treatment and antidote administration
Routes of exposure
Skin:
Inhalation:
Signs and symptoms of exposure:
May cause local irritation or stinging
effect.
Airborne concentrations of sodium
azide can cause headaches,shortness
of breath, increased respiration and
heartbeat, nausea and dizziness.
Ingestion:
Nausea, headache, dizziness,
shortness of breath, increased
respiration and pulse.
Eyes:
Eyes will appear to be bloodshot
because of dilated blood vessels. This
may be the first symptom of sodium
azide exposure
Emergency and first aid procedures:
Wash off with soap and plenty of water.
Call a physician
If breathing is irregular or stopped, administer
artificial respiration.
Ventilation with a ventilator is recommended.
As soon as possible treatment with corticoid
aerosol (spray). In the case of unconsciousness:
Treatment with methaemoglobin forming agents
(4-DMAP). If there is a risk of loss of
consciousness, place and transport affected person
in the recovery position.
Clean mouth with water and drink afterwards
plenty of water.Call a physician immediately.If
there is a risk of loss of consciousness, place and
transport affected person in the recovery
position.Never give anything by mouth to an
unconscious person.Treatment with
methaemoglobin forming agents (4-DMAP).
In case of eye contact, remove contact lens and
rinse immediately with plenty of water, also
under the eyelids, for at least 15 minutes. Protect
unharmed eye. Ophthalmic treatment may be
necessary.
5.FIRE FIGHTING MEASURES
Flammable properties:
Flash point: Not flammable. Decomposes at 275 degrees C
Flash point method: Not applicable.
Auto-ignition temperature: Not applicable.
Upper flammability limit (volume % in air): Not applicable.
Lower flammability limit (volume % in air): Not applicable.
Extinguishing media: Fight fires with dry powder, dry chemical, and/or dry sand Sodium metal is a
decomposition product of sodium azide fires. Fight fires with metal fire extinguishing fire extinguishers or dry
sand. Do not use water.
Unusual fire and explosion hazards: Water will react with decomposed sodium azide
Special Hazards during Fire-Fighting: Avoid gases, vapors, and smoke. Keep away from open flames, hot
surfaces and sources of ignition. In case of fire or overheating toxic/harmful vapors may be liberated.
Fire Fighting/Advice: Collect contaminated fire extinguishing water separately. This must not be discharged into
public drains. Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local
regulations.
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Special Protective Equipment for Fire-Fighters: In the event of fire, wear self-contained breathing apparatus
and full protection clothing.
6. ACCIDENTAL RELEASE MEASURES
Personal Protection Equipment: Use personal protective equipment. Wear appropriate respiratory protection.
Ensure adequate ventilation. Evacuate personnel to safe areas. Keep people away from and upwind of spill/leak. Do
not subject to grinding/shock/friction. Do not get in eyes, on skin, or on clothing.
Skin and body protection: To protect against direct skin contact personal protective equipment (in addition to
normal working clothes) is required.
Methods for Cleaning up: Use mechanical handling equipment such as scoops or shovels. Fill in a labeled
container and properly dispose. Use containers made of steel, glass or plastic.
7. HANDLING AND STORAGE
Handling: Avoid contact with eyes and skin (wear appropriate personal protective equipment: glasses, gloves and
mask in case of dust). Do not breathe dust or vapors. Prevent any contamination of the environment via the sewers
or water sources.
Fire prevention: Control static electricity and other ignition sources.
Appliance Requirements:
Unsuitable material: Heavy metals such as copper, silver, lead mercury and alloys containing heavy metals such as
brass. Do not combine sodium azide with low-pH liquids and vapors, since hydrazoic acid may form.
Storage container: Only use containers specifically approved for the substance/product. Local authorities may limit
the quantity that can be stored.
Specific uses: Analytical chemistry, automotive airbags and other nitrogen gas generator functions, pharmaceutical
and chemical intermediate, preservative, proposed use as an active ingredient in broad spectrum agricultural
pesticides.
Storage: Store away from water in dry climate. Keep container closed when not in use. Sodium Azide is
hygroscopic and will agglomerate when exposed to moisture. American Pacific recommends that containers be
inspected upon arrival for damage which may happen during transit. American Pacific recommends that Sodium
Azide should be stored in temperature and humidity controlled storage areas. If this is not possible and
depending upon the environmental conditions of the storage area the desiccant should be checked and changed if
necessary particularly when the Sodium Azide is not consumed for a lengthy time (150 days). Higher humidity
areas may require the desiccant be changed monthly to maintain the integrity of the Sodium Azide.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Technical measures: Ventilate as necessary to minimize exposure levels. Inspect and clean ventilation systems
regularly.
Control Parameters:
Ingredient Name
Sodium Azide
ACGIH
0.29 mg/m3 (Nuisance Dust)
0.11 ppm Vapor
OSHA
0.3 mg/m3 (Nuisance Dust)
0.1 ppm Vapor (Skin)
Exposure controls:
Appropriate engineering controls: Ventilate as necessary to minimize exposure levels. Inspect and clean
ventilation systems regularly.
Personal protective equipment:
Skin Protection: Wear protective clothing suitable to minimize skin contact with solid sodium azide or solutions
containing sodium azide. Shower and change clothes after exposure to sodium azide. Remove dust from skin by
vacuuming or brushing while minimizing airborne dust. Wash contaminated clothing in a controlled area to prevent
exposure to personal clothing and to prevent sodium azide contamination in drains containing copper and lead or
other heavy metals.
Hand Protection: Hand protection, gloves made of butyl-rubber. Remove any sodium azide contamination before
eating, drinking, smoking, applying cosmetics, etc.
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Eye Protection: Wear safety glasses or full-face respirators. Use equipment for eye protection tested and approved
under appropriate government standards
Respiratory Protections: Where risk assessment shows air-purifying respirators are appropriate use a full-face
particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If
the respirator is the sole means of protection, use a full-face air supplied respirator. Use only respirators and
components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Additional Recommendations: Wash thoroughly after handling. Eyewash and safety equipment must be readily
available.
Methods for Cleanup: Use mechanical handling equipment such as scoops or shovels. Fill in labeled container and
dispose according to regulations. Use containers made of steel, glass or plastic
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance:
White crystal
Physical state:
Solid
Specific gravity
(water = 1.0):
1.846
Relative Density:
1.850 g/cm3
Solubility in
water (weight %):
20% at 20ºC
Partition
coefficient:
noctanol/
Water:
No data available
Vapor density
(air = 1.0):
at 20° C, not
applicable
Vapor pressure:
solid, not
applicable
Molecular
weight:
64.99 g/mol
pH: 9.0 – 9.6
Chemical formula:
NaN3
Auto Ignition
Temperature:
No data available
Upper
flammability or
explosive limits:
Not applicable
Lower flammability or
explosive limits:
Not applicable
Evaporation rate:
Not applicable
Flash point:
Not flammable (Flash
point method and
additional
flammability data are
found in Section 5.)
Decomposition:
Products of sodium azide
are nitrogen gas, sodium
oxide, NOx and sodium
metal which will be
water reactive
Boiling point: Not
applicable
Odor:
No odor to slight
ammonia odor
Melting point:
Decomposes at 275° C
10. STABILITY AND REACTIVITY
Reactivity: Reacts spontaneously with low pH materials forming toxic and explosive hydrazoic acid (HN3). Sodium
azide may react with strong oxidizers, heavy metals, alloys and salts containing heavy metals. Avoid materials such
as brass, copper, lead, silver or bronze which contain heavy metals. Hazardous polymerization will not occur.
Chemical stability: Very stable in dry environments and when stored in unopened original containers.
Conditions to avoid: Avoid elevated temperatures over 275º C which can cause decomposition
Materials to avoid: Avoid exposure to all acids. Avoid exposure to heavy metals, alloys containing heavy metals
such as brass, copper, lead, low-pH (<9.0) liquids or vapors and sulphur carbon, dimethylsulphate, halogenated
hydrocarbon, dichloromethane
Hazardous Reactions: Contact with low pH liquids and vapors releases highly toxic and energetic hydrazoic acid
vapors. Burning sodium azide can generate large quantities of gases which should not be confined and allowed to
vent. Evacuate the immediate area if necessary. Do not fight a fire if in confined vessel.
Hazardous Decomposition Products: Avoid low (<9.0) pH materials which will form hydrazoic acid (HN3)
vapors. Hydrazoic is instable and can be explosive.
Decomposition of sodium azide will result in sodium metal which is water reactive, and sodium oxide which is
caustic. Nitrogen gas may evolve in large quantities which may be hazardous if confined.
11. TOXICOLOGICAL INFORMATION
As with any toxicant, assessing dose and exposure are required to understand potential toxicity.
Sodium Azide can lower blood pressure and cause headaches, shortness of breath, faintness and increase heart rate.
Sodium Azide is a poison and may be fatal if significant doses are ingested. Other routes of exposure, such as
inhalation or absorption, can also lower blood pressure and cause headaches, shortness of breath, faintness, loss of
consciousness, and increased heart rate. Sodium azide is a vasodilator which will cause blood shot eyes. This is
often an early warning indication of exposure.
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Immediate (acute) effects:
Oral LD50: rat; 27 mg/kg
Oral LD50: mouse; 27 mg/kg
Intravenous LD50: mouse; 19 mg/kg
Dermal LD50: rate > 5,000 mg/kg
Delayed (subchronic and chronic) effects:
No long-term health effects have been reported
Oral TDLo: rat; 2,730 mg/kg/78 wk (HSDB, 2005)
Oral TD: rat; 5,460 mg/kg/78 wk (HSDB, 2005)
90-Day rat oral gavage subchronic toxicity assay
NOAEL: rat; 3.57 mg/kg/day for hunched posture and reduced body weight.
Oral LOAEL: rat; 20 mg/kg/day, 2 weeks
Oral LOAEL: rat, 10 mg/kg/day, 13 weeks
Oral LOAEL: rat, 5 mg/kg/day, 2 years
Rat Oral Maternal and Development Toxicity (exposure during gestation days 6-19)
NOAEL: 5 mg/kg/day based on maternal mortality, decreased maternal body weight, and decreased fetal body
weight
LOAEL: 17.5 mg/kg/day (dose reduced to 10 mg/kg/day during gestation days 10-12)
Non-teratogenic (Faqi et al., 2008)
Carcinogen:
IARC: NO
NTP: NO
OSHA: NO
Other Medical conditions aggravated by exposure: Similar to most nitrates, sodium azide can cause sudden
decrease in blood pressure worsened by people already experiencing hypertension or taking medications to control
hypertension. Respiratory conditions: can cause shortness of breath and respiratory irritation.
12. ECOLOGICAL INFORMATION
Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter noncontainment drains. Discharge into the environment i.e. public drains and waterways must be avoided.
Toxicity Data:
Bluegill sunfish LC50 –0.68 ppm
Rainbow trout LC50 –0.8 ppm
Shrimp LC50 – 5.0 ppm
13. DISPOSAL CONSIDERATIONS
Important Remarks: Decontamination of sodium azide or its solutions is carried out by reaction with sodium
nitrite in presence of sulfuric or nitric acid and should be done only be trained and experienced persons.
The generation of waste should be avoided or minimized wherever possible. Avoid dispersal of spilled material and
runoff and contact with soil, waterways, drains and sewers. Disposal of this product should at all times comply with
the requirements of environmental protection and waste disposal legislation and any regional local authority
requirements. Use mechanical handling equipment. Fill in labeled, re-sealable container(s) made of stainless steel,
glass or plastic.
Disposal should be in accordance with applicable regional, national and local laws and regulations. Local
regulations may be more stringent than regional or national requirements. Contaminated, empty containers are to be
handled as the substance it contained.
Refer to Section 7: Handling and Storage and Section 8: Exposure Controls/Personal Protection for additional
handling information and protection of employees.
RCRA:
Is the unused pure commercial product a RCRA hazardous waste if discarded? Yes
If yes, the RCRA ID number is: P105
If no (due to lack of commercial purity or mixing or other issues), the user must be careful to evaluate potential
reactivity as a D003 due to sodium azide’s ability to react with neutral or low pH water to create the toxic gas
Hydrazoic acid. Waste will normally fit into one of the two categories. The user should also carefully evaluate the
“mixture rule” before determining P105 is not the correct classification. In some uses, other waste codes may apply
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Document Title: Sodium Azide with Cab-O-Sil Safety Data Sheet
due to other characteristics of mixtures. The user must evaluate and classify wastes correctly without respect to the
above discussion that is intended to be helpful but not a complete classification evaluation.
14. TRANSPORT INFORMATION
Proper Shipping Name:
UN1687, Sodium Azide, 6.1, PG II
Land transport (ADR/RID), Marine transport (IMDG), Air transport (ICAO/IATA)
UN Number
1687
Class
6.1- Poisonous material
Packaging Group
II
Classification Code
60
Environmental Hazards: Please see section 12. Prevent any contamination of the environment via the sewers or
water sources.
Special precautions for user: Please see section 7
15. REGULATORY INFORMATION
U.S. Federal regulations: TSCA 8(b) inventory: Listed
SARA 302/304/311/312 extremely hazardous substances: Sodium Azide
SARA 302/304 emergency planning and notification: Sodium Azide
SARA 302/304/311/312 hazardous chemicals: Sodium Azide
SARA 311/312 SDS distribution - chemical inventory - hazard identification: Sodium Azide: Immediate health
hazard
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
SARA 313
Product name: Sodium Azide
CAS number: 26628-22-8
Concentration: 100%
Name
Sodium
Azide NaN3
CAS/313
Category
Codes
26628-22-8
Section 302
(EHS) TPQ
500
Section
304 EHS
RQ
1,000
CERCLA
RQ
Section
313
RCRA
Code
CAA
112(r) TQ
1,000
313
P105
N/A
State Right-To-Know: In addition to the ingredients found in Section 2, the following are listed for state right-toknow purposes.
Ingredient Name
Sodium Azide
SARA/CERCLA RQ (lbs)
SARA EHS TPQ (lbs)
Examine local regulations to
Examine local regulations to
determine
determine
Due to the rapidly changing regulatory environment in individual states, it is very difficult to maintain up to date
information for each state in a safety data sheet. The user must examine the local regulations in force and comply
with all requirements.
Regulations:
Listed on the Toxic Substances Control Act (TSCA): Yes
Information about limitation of use: For use only by technically qualified individuals.
United States OSHA: Covered by Hazcom
This preparation was classified in compliance with the following directives and regulations:
(EC) No 1907/2006 (REACH)
(EC) No 1272/2008 (CLP)
(EC) No 453/2010
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Document Title: Sodium Azide with Cab-O-Sil Safety Data Sheet
16. OTHER INFORMATION
Not intended to be a foodstuff, this material is a poison. It has been used as a precursor for various drugs, as an
active ingredient in automotive airbags, and many other uses.
Additional Classification Systems:
Hazardous Materials Identification System (HMIS) ratings (scale 0 – 4)
Health Hazard
Fire Hazard
Reactivity
PPE
3
1
2
X
X - Consult your supervisor or S.O.P. for SPECIAL handling directions
National Fire Protection Association (NFPA) ratings (scale 0 – 4)
IMPORTANT: The information presented herein, while not guaranteed, was prepared by competent technical
personnel and is true and accurate to the best of our knowledge. NO WARRANTY OR GUARANTEE, EXPRESS
OR IMPLIED, IS MADE REGARDING PERFORMANCE, STABILITY OR OTHERWISE. This information is
not intended to be all-inclusive as to the manner and conditions of use, handling and storage. Other factors may
involve other or additional safety or performance considerations. While our technical personnel will be happy to
respond to questions regarding safe handling and use procedures, safe handling and use remains the responsibility of
the customer. No suggestions for use are intended as, and nothing herein shall be construed as a recommendation to
infringe any existing patents or violate any Federal, Other National Governmental Entity, State, Provincial, or local
laws. The User of this material is responsible for safe use and handling of the material in all aspects of the user’s
business. The manufacturer cannot control or warranty the user for any safety or environmental consequences
resulting from misuse or handling of this material.
References:
Faqi AS, Richards D, Hauswirth JW, Schroeder R. 2008. Maternal and developmentalToxicity study of sodium
azide in rats.RegulToxicolPharmacol 52(2):158-62.
Hazardous Substances Data Bank (HSDB). 2005. Sodium Azide; CASRN: 26628-22-8. National Library of
Medicine, Bethesda, MD
NCI (National Cancer Institute). 1981. Ninety-day subchronic toxicity test with sodium azide in Fischer 344 rats.
Study No. 5650.08, report submitted by Microbiological Associates, Bethesda, MD.
Rumack BH. 2010. POISINDEX(R) Information System Micromedex, Inc., Englewood, CO, CCIS Volume 146
Rev: 10
Effective Revision Date: 25 May 2016
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