SECTIONS IV – VIII: Detailed information on each component of the proposal PLEASE COMPLETE THE FOLLOWING SECTIONS FOR EACH COMPONENT Please copy sections IV – VIII, as many times as there are components Please note: a component refers to a disease, i.e. your proposal will have more than one component only if it covers more than one disease. There should only be 1 component per disease. If there are any objectives or broad activities within a particular component that are of a system-wide/cross-cutting nature such as capacity building or infrastructure development that may go beyond the scope of that particular component, please indicate those aspects clearly and specify how they would relate to other components of the proposal when detailing them in Question 27. (Guidelines para. IV.47 – 49) If this is a fully integrated proposal, where two or more components are linked in such a way which would not make it realistic or feasible to separate, mark the boxes in Table IV.23 to identify all diseases which would be directly affected by this integrated component. (Guidelines para. 50) SECTION IV – Scope of proposal 23. Identify the component that is detailed in this section (mark with X): Table IV.23 Component HIV/AIDS (mark with X): Tuberculosis X Malaria HIV/TB 24. Provide a brief summary of the component (Specify the rationale, goal, objectives, activities, expected results, how these activities will be implemented and partners involved) (2–3 paragraphs): Malaria in Sudan is a major public health problem. The whole country is considered endemic, with varying degrees of endemicity. The country shoulders an estimated 50% of all malaria cases in the WHO Eastern Mediterranean Region an estimated 7.5 million cases resulting in 35 000 deaths per year. The disease accounts for about about a fifth of outpatient cases, nearly a third of inpatient cases and a fifth of all hospital deaths. The malaria case fatality rate for paediatric hospitals ranges between 5% and 15%. The overall goal of RBM in Sudan is to reduce the malaria burden to an extent that it is no longer a public health problem. Application Form for Proposals to the Global Fund 22 Page 22 of 49 The objective of the Malaria component is to malaria morbidity and mortality by40% by 2010. The specific objectives, main activities and outcomes are as follows: 1. To improve disease management: a. Introduce malaria home management b. Improve clinical diagnosis and treatment c. d. Improve laboratory diagnosis Ensure availability and rational use of antimalarials 2. To improve disease surveillance and epidemic management: a. Establish early warning system b. Ensure rapid response to epidemics 3. To implement cost-effective and evidence-based multiple prevention a. Develop policy on rational use of insecticides interventions: b. Scale up use of insecticide treated nets (ITNs ) c. Prevent malaria during pregnancy through introduction of intermittent preventive treatment (IPT) with sulphadoxine-pyremethamine (SP) through antenatal clinics 4. To upgrade capacity and strengthen institutional work: a. Expand the RBM support system in 13 states in the southern and western parts of the country b. Support and expand the available training centers Implementation: Technical intervention is based on epidemiological stratification of malaria, as seen in the table below. More emphasis will be given to areas of high malaria transmission. Application Form for Proposals to the Global Fund Page 23 of 49 Strata Desert fringe Endemicity Hypoendemic Population States Selected Interventions 2,000,000 Northern, River Nile, Red Sea except Port Sudan and North Darfour except Elfashir Case management, ITNs, source reduction where appropriate (with community involvement), IRHS during emergency, epidemic preparedness Case management, ITNs, IRHS during emergency, epidemic preparedness Poor savannah with seasonal malaria Hypoendemic Mesoendemic 15,000,000 Rural areas in Greater Darfour, Kordofan, Blue Nil, White Nile, Sinna Gezira Gedarif, Kassala, Khartoum Stable perennial transmissio n HyperendemIc 4,000,000 Southern Sudan Case management, ITNs and IPTs. 8,000,000 Khartoum and all large cities e.g. Port Sudan, Wad Medani Case management, ITNs, source reduction where appropriate (with community involvement), larviciding, IRHS during emergency 2,000,000 All large- scale irrigated schemes (Gezira, Elrahad, Kinana, Asalia, West Sinnar, New Halafa and Elzidab) Case management, ITNs, targeted IRHS, IPTs, source reduction where appropriate (with community involvement) during emergency Urban malaria Hypoendemic Mesoendemic Irrigated Schemes Usually in the mesoendemic zones The implementation of RBM interventions and activities will be at all levels and will be the responsibility of all partners (Government, NGOs, unilateral, bilateral and multilateral organizations, private sector and community-based organizations). Management of the malaria component will therefore focus on brokering and coordinating the partnership. 25. Indicate the estimated duration of the component Table IV.25 From (month/year): January 2003 Application Form for Proposals to the Global Fund 24 Page 24 of 49 To (month/year): Dec. 2007 26. Detailed description of the component for its FULL LIFE-CYCLE: Please note: Each component should have ONE overall goal, which should translate into a series of specific objectives. In turn each specific objective should be broken-down into a set of broad activities necessary to achieve the specific objectives. While the activities should not be too detailed they should be sufficiently descriptive to understand how you aim to achieve your stated objectives. Indicators: In addition to a brief narrative, for each level of expected result tied to the goal, objectives and activities, you will need to identify a set of indicators to measure expected result. Please refer to Guidelines paragraph VII.77 – 79 and Annex II for illustrative country level indicators. Baseline data: Baseline data should be given in absolute numbers (if possible) and/or percentage. If baseline data is not available, please refer to Guidelines paragraph VII.80. Baseline data should be from the latest year available, and the source must be specified. Targets: Clear targets should be provided in absolute numbers (if possible) and percentage. For each level of result, please specify data source, data collection methodologies and frequency of collection. An example on how to fill out the tables in questions 26 and 27 is provided as Annex III in the Guidelines for Proposals 26. Goal and expected impact (Describe overall goal of component and what impact, if applicable, is expected on the targeted populations, the burden of disease, etc.), (1–2 paragraphs): The overall goal of RBM in Sudan is to reduce the malaria burden to the extent that it is no longer a public health problem. This goal is to be achieved through overall health sector development, improved strategic investments in malaria control, and increased coverage of malaria treatment and prevention interventions, especially at the community level. Expected impact: • • Raising awareness and empowering the community so that the community can take actions that add to the program sustainability Reduction of malaria disease burden (morbidity and mortality) Please note: the impact may be linked to broader national-level programmes within which this component falls. If that is the case, please ensure the impact indicators reflect the overall national programme and not just this component. Please specify in Table IV.26.1 the baseline data. Targets to measure impact are only required for the end of the full award period Table IV.26.1 Application Form for Proposals to the Global Fund Page 25 of 49 Goal: To reduce the malaria burden to an extent that it is no longer a public health problem Impact indicators (RBM Global indicator) Baseline Target (last year of proposal) (Refer to Annex II) Year: Year: 2007 Malaria death rate (probable and confirmed) among hospital admitted cases N/A Reduced by 40% from baseline No. of malaria cases, simple and severe complicated (probable and confirmed) among total health facilities attendence N/A Reduced by 40% from baseline Proportion of households having at least one treated bednet N/A Increased by 50% from base line Percentage of patients with simple malaria getting correct treatment at health facility and community level according to national guidelines within 24 hours of onset of symptoms N/A Increased by 50% from baseline Percentage of health facilities reporting no disruption of stock of antimalarial drugs (as specified in the national drug policy) for more than one week during the previous three months N/A Increased by 50% from baseline * Annual targets may be adjusted in line with baseline survey results 27. Objectives and expected outcomes (Describe the specific objectives and expected outcomes that will contribute to realizing the stated goal), (1 paragraph per specific objective): Objective I: To treat malaria cases according to the national guidelines in >90% of cases: The capacity and access to early diagnosis and treatment at all level should be improved. Home management will be introduced in areas with high transmission and low coverage with services. Chloroquine (CQ) and sulphadoxine-pyremethamine (SP) will be under monitoring. Combination therapy (CT) will be tested in certain areas (Q+SP and artesinate-based combination). Guidelines for simple and severe malaria will be updated every 2–3 years (to fit with WHO guidelines and with the result of studies) and distributed to prescribers. Training of health personnel will be conducted within the context of IMCI. Application Form for Proposals to the Global Fund 26 Page 26 of 49 Expected outcomes: Simple and severe malaria case management will be improved at all levels, leading to reduction of mortality and suffering. To treat malaria cases according to the national guidelines in >90% of cases as Objective I: early as possible Outcome/coverage indicators Baseline Targets (Refer to Annex II) Year: Year 2: 2003 Year 3: 2004 Year 4: 2005 % of mothers/ caregivers able to recognize signs and symptoms of severe febrile illness N/A 25% 50% 75% 100% % of children <5 with fever treated according to IMCI guidelines N/A 25% 50% 90% 90% % of patients with uncomplicated malaria getting correct treatment at health facility N/A 75% 75% 100% 100% % of health facilities with no disruption of antimalarials for 2 wks in the last 3 months N/A 50% 75% 90% 90% Year 5: 2006 * Annual targets may be adjusted in line with baseline survey results a. Broad activities related to each specific objective and expected output (Describe the main activities to be undertaken, such as specific interventions, to achieve the stated objectives) (1 short paragraph per broad activity): • • • • National guidelines will be updated periodically (every 2–3 years) in light of therapeutic efficacy studies. The guidelines will be distributed to prescribers in the form of booklets and a flow-chart. (CQ+SP) as a combination therapy will be introduced in pilot areas, and at the same time artesinate-based CT will be studied in certain areas. Training of health personnel/ mothers in community and PHC units will be carried out in collaboration with IMCI. IEC will follow the introduction of each new guideline and will be sustained. Application Form for Proposals to the Global Fund Page 27 of 49 • Efforts will be made to maintain availability of drugs at all levels free of charge. Objective I: Broad activities To treat malaria cases according to the national guidelines in >90% of cases as early as possible Process/Output Baseline indicators (indicate one per activity) (Refer to Annex II) (Specify year) Year 1 2003 Year 2 2004 Updated document actually distributed. 0 80% 100% NMCP, SMCP, NGOs, private sector Operational resea Research completed 0 50% 100% NMCP, SMCP, NGOs, research institutes Training (100 in % of personnel each state trained out of the *26=2600) target 0 20% (520) 60% NMCP, SMCP, NGOs, (1560) private sector Updating treatment guidelines Targets Responsible/Implementin g agency or agencies IEC % of target group with adequate knowledage, attitude and practice (>80%) N/A 50% 80% NMCP, SMCP, NGOs, private sector Availing drugs % of facilities with no disruption of drugs for 2 weeks during the last 3 months N/A 25% 50% NMCP, SMCP, NGOs, private sector * Annual targets may be adjusted in line with baseline survey results 27. Objectives and expected outcomes (Describe the specific objectives and expected outcomes that will contribute to realizing the stated goal), (1 paragraph per specific objective): Objective II: To improve malaria laboratory diagnosis to reach >90% sensitivity and specificity in 100 districts: The situation of malaria laboratory diagnosis (in public, private and NGOs sectors) will be explored. The training, supplies and equipment as well as supervision will be directed according to the results. The state quality assurance (QA) laboratory will be strengthened to carry out this work. Expected outcomes: Application Form for Proposals to the Global Fund 28 Page 28 of 49 Laboratory capacity diagnosis of malaria will be improved with subsequent rise in sensitivity and specificity. Objective II: To improve malaria laboratory diagnosis to reach >90% sensitivity and specificity at 100 districts Outcome/coverage indicators Baseline Targets (Refer to Annex II) Year: Year 2: 2003 Year 3: 2004 Year 4: 2005 Year 5: 2006 % of districts with improved laboratory diagnosis (target 100 district ) N/A 26% (26) 50% (50) 75% (76) 100% (100) % of laboratories with >90 sensitivity and specificity (total no. will be available later) N/A 50% 75% 90% % of states with functioning QA laboratory N/A 50% (13) 75% (20) 100% (26) 90% 100% (26) * Annual targets may be adjusted in line with baseline survey results a. Broad activities related to each specific objective and expected output (Describe the main activities to be undertaken, such as specific interventions, to achieve the stated objectives) (1 short paragraph per broad activity): As this is a problem-solving approach, in each district the following activities will be carried out: • • • • • • Assessment of laboratory work in 100 districts (one from each state) and recommendations for a solution package for each area Provision of necessary S&E as described in the recommended package Refresher courses (100 courses/7 days)) for laboratory technicians (at least 2000) as indicated by the package Regular supervision of quality assurance (QA) laboratories over services laboratories and enforcement of Giemsa stain use laboratories at urban area level Strengthening of existing 13 QA laboratories services and developing new ones in another 13. Development and distribution of documents and bench aids on laboratory diagnosis sites through provision of equipment and consumables Development and distribution of documents and bench aids on laboratory diagnosis Application Form for Proposals to the Global Fund Page 29 of 49 Objective II: Broad activities To improve malaria laboratory diagnosis to reach >90% sensitivity and specificity at 100 districts (at least one in each state during the first 2 years) Process/Output indicators (indicate one per activity) (Refer to Annex II) Baseline Targets Responsible/ Implementing agency or agencies (Specify year) Year 1 2003 Year 2 2004 0 26% (26) 50% (50) NMCP, SMCP, NGOs, private sector Provision of S&E % of S&E available out of the total need 0 50% 75% NMCP, SMCP, NGOs, private sector Training (target 2000) % of trained personnel 0 26% (520) 50% (1000) NMCP, SMCP, NGOs, private sector Supervision % of the districts visited 0 90% 90% NMCP, SMCP, NGOs, private sector QA laboratories establishment (26 labs) % of functioning laboratories out of the total N/A 50% (13) 75% (20) NMCP, SMCP Distribution of guidelines and bench aids % of laboratory personnel with bench aids and guidelines N/A 26% (520) 50% (1000) Situation analysis % of districts finished with situation analysis out of target NMCP, SMCP, NGOs, private sector * Annual targets may be adjusted in line with baseline survey results 28. Objectives and expected outcomes (Describe the specific objectives and expected outcomes that will contribute to realizing the stated goal), (1 paragraph per specific objective): Objective III: To reduce deaths due to malaria at hospital level by 75% from the registered deaths during 2002 by the end of the period This a problem-solving approach to address malaria mortality. Effort at hospital level are required not only to adequately manage the severe malaria cases but also to identify the determinants of severe malaria and malaria mortality. Admitted malaria patients will receive the necessary treatment and at the same time they will be given an in-depth interview to identify mortality determinants and any related behavioural, social or economic factors. Based on such interviews, malaria information, education and Application Form for Proposals to the Global Fund 30 Page 30 of 49 communication (IEC) programme will be developed and implemented. So, this objective entails a package composed mainly of focal discussion with caregivers, proper diagnosis, treatment and health education. Expected outcomes: Improved quality of care for severe complicated malaria at hospital level with free drugs will eventually reduce malaria mortality Objective III: To reduce deaths due to malaria at hospital level by 75% from the registered deaths during 2002 by the end of the period Outcome/coverage indicators (Refer to Annex II) Baseline Targets Year: Year 2: 2003 Year 3: 2004 Year 4: 2005 Year 5: 2006 % of hospitals implementing the suggested package (target 75 hospitals) N/A 60% (45) 100% (75) 100% (75) 100% (75) % of reduction in malaria mortality at each hospital separately N/A 50% 75% 75% 75% 100% 100% % severe malaria cases N/A 50% 75% treated according to policy at hospital where the package was implemented. * Annual targets may be adjusted in line with baseline survey results 27.1. Broad activities related to each specific objective and expected output (Describe the main activities to be undertaken, such as specific interventions, to achieve the stated objectives) (1 short paragraph per broad activity): In each hospital (starting with target hospitals with higher mortality during 2001– 2002) the broad activities include: • Focal group discussion (FGD) with caregivers with review of hospital set-up aiming to identify mortality determinants in 75 hospitals (each separately) with suggestion of solution package • Assessment of patient’s knowledge, attitudes, practices and ability to afford treatment • Appropriate training (case management, laboratory) • Procurement of supplies and equipments (S&E) for case management including (as 2 packages): diagnostic tools package for each doctor and patient treatment package • Formation of mortality committees at hospital level to monitor the progress with introduction of case auditing Application Form for Proposals to the Global Fund Page 31 of 49 • • • Supportive supervision from state and national level control program National seminar to discuss the results of the first round and to launch the second round Operational research: (treatment of SCM with artemether or quinine: cost and outcome, 3-day treatment with quinine (Q) followed by effective antimalarial compliance, cost and outcome compared with the current regimen – Q for 7 days) Objective III: To reduce deaths due to malaria at hospital level by 75% from the registered deaths during 2002 Broad activities FGD with caregivers at each hospital separately guided by a trained team KAP to assess factors Related to the patient Procurement of diagnostic package for doctors (composed of basic diagnostic tools) Procurement of treatment package for patients (drugs,fluids) Training of at least 30 staff from each hospital (doctors, laboratory staff nurses) Formation of hospital mortality committee for case auditing Process/Output indicators (indicate one per activity) (Refer to Annex II) Baseline Targets Responsible/Implementing agency or agencies (Specify year) Year 1 2003 Year 2 2004 % of targeted hospitals in which FGD was carried out 0 60% (45) 100% (75) NMCP, SMCP, NGOs % of targetd hospitals carried out KAP study % of targeted hospitals provided doctors with diagnostic package 0 60% (45) 100% (75) SMCP, Mortality committee 0 60% (45) 100% (75) NMCP, SMCP, Mortality committee % of hospitals with 0 ready-made treatment package 60% (45) 100% (75) NMCP, SMCP, Mortality committee No. of health personnel trained 20% (300) 50% (750) NMCP, SMCP, Mortality Committee 60% (45) 80% (60) SMCP N/A % of hospitals with N/A functioning committee Application Form for Proposals to the Global Fund 32 Page 32 of 49 Supervision to hospitals involved Researches (minimum 2 research studies) % of hospitals visited twice per year out of total target No. of research studies initiated or completed 0 80% (36) 80% (60) NMCP, SMCP N/A 50% 100% NMCP, SMCP, Academic institutes * Annual targets may be adjusted in line with baseline survey results 27. Objectives and expected outcomes (Describe the specific objectives and expected outcomes that will contribute to realizing the stated goal), (1 paragraph per specific objective): Objective IV: To detect and adequately respond to malaria epidemics within 2 weeks of initiation: • An epidemic in Sudan is defined as occurrence of cases clearly in excess of the normal expected number. The normal expected number is the average of at least 3 years, or the average + 2 SD Establishing a system for proper forecasting and for early detection and initiating measures for quick containment is critical for sustainable reduction of the number and severity of epidemics. • All epidemic-prone states (16 states) are to be supported to establish an effective and efficient system to respond to and contain epidemics through proper planning, timely surveillance and maintaining an adequate stock of drugs. • Closer collaboration with National Disaster Committee (Multidisciplinary, higher committee dealing with disasters in Sudan) is needed for coordination of efforts in managing epidemics. Question 27 must be answered for each objective separately. Please copy Question 27 and 27.1 as many times as there are objectives. Please note: the outcomes may be linked to broader programmes within which this component falls. If that is the case, please ensure the outcome/coverage indicators reflect the overall national programme and not just this component. Specify in Table IV.27 the baseline data to measure outcome/coverage indicators.Targets are only required for Year 2 onwards. Table IV.27 Objective IV: To detect and adequately respond to malaria epidemics within 2 weeks of initiation Outcome/coverage indicators Baseline Targets Application Form for Proposals to the Global Fund Page 33 of 49 (Refer to Annex II) Year: % of state teams able to use composite indicator for forecasting correctly (according to RBM guidelines: malaria early warning system) N/A 50% (13) 100% (26) 100% (26) 100% (26) Proportion of states meeting criteria for epidemic preparedness as stated by the NMCP N/A 30% (8) 50% (13) 75% (20) 100% (26) Proportion of states with buffer N/A stock 30% (8) 50% (13) 75% (20) 100% (26) Year 2:2003 Year 3: 2004 Year 4: 2005 Year 5: 2006 * Annual targets may be adjusted in line with baseline survey results 27.2. Broad activities related to each specific objective and expected output (Describe the main activities to be undertaken, such as specific interventions, to achieve the stated objectives) (1 short paragraph per broad activity): Strengthening of early detection through sentinel site monitoring system: • Re-assess current sentinel sites, to be at least 5 sites per state • Ensure weekly monitoring of epidemic indicators during high risk months • Develop and distribute simple guidelines for forecasting, early detection and epidemic containment • Conduct training workshops for state and sentinel site staff on the above guidelines. Establishment of epidemic warning thresholds for states and areas at risk of seasonal malaria epidemics: • Conduct desk analysis of historic malaria morbidity and mortality data • Strengthen links with related sectors (metrology, agriculture, etc.) for monitoring malaria risk factors. Mapping and forecasting of seasonal malaria epidemics risk areas: • Expand forecasting project to remaining states (now started in five states supported by RBM). Improvement of feedback on malaria situation to states and sentinels sites: • Develop and implement standard timely feedback system from NMCP to states and related sectors. Application Form for Proposals to the Global Fund 34 Page 34 of 49 Finalization of malaria contingency plan for federal and state level: • Adapt epidemic response contingency plan at state level. Improvement of availability of buffer stock at onset of epidemic season (covering at least two weeks of control intervention): • Developing buffer stock management system for S&E. • Make available adequate supplies for malaria epidemics. Please note: Process/output indicators for the broad activities should directly reflect the specified broad activities of THIS component. Specify in Table IV.27.1 below the baseline data to measure process/output indicators. Targets need to be specified for the first two years of the component. For each broad activity, specify in Table IV.27.1 who the implementing agency or agencies will be. Table IV.27.1 Objective IV: To detect and adequately respond to malaria epidemics within 2 weeks of initiation Broad activities Process/Output indicators (indicate one per activity) (Refer to Annex II) Baseline Targets (Specify year) Year 1 2003 Responsible/ Implementing agency or agencies Year 2 2004 Training for statelevel rapid assessment and response teams (90) No. of teams trained N/A 50% (45) 100% (90) NMCP, NGOs, Academic institutes Collection and analysis of historic malaria morbidity and mortality data (1990–2002) at state and sentinel sites. % of sites with epidemic threshold N/A 25% 75% NMCP, SMCP Application Form for Proposals to the Global Fund Page 35 of 49 Development and implementation of standard timely feedback system % of states/sectors recieving feedback within one week of filing the report N/A 100% (30 ) 100% (30) NMCP, SMCP and Partners. Establishment of buffer stock management system in the existing supply infrastructure % of states having system to maintain buffer stock N/A 30% (8) 75% (20) NMCP, central medical Store and NGOs Adoption of epidemic contingency plan at state level % of states adopting the plan N/A 50% (13) 75% (20) NMCP, SMCP and Partners * Annual targets may be adjusted in line with baseline survey results 27. Objectives and expected outcomes (Describe the specific objectives and expected outcomes that will contribute to realizing the stated goal), (1 paragraph per specific objective): Objective V: to increase the number of pregnant mothers protected from malaria by 80% in high transmission areas This objective will be achieved by distribution of Long Lasting Insecticide Treated Nets (LITNs) and by introducing IPT with SP. Pregnant mothers in high transmission strata (around 900 000), especially in irrigated schemes and high transmission areas in the South, will be encouraged to use LLITNs by providing subsidized or free of charge LLITNs. Public–private partnership will be encouraged to promote the importation of bednets, and to create demand for their use by pregnant women and children under 5 years. In areas of high transmission, intermittent preventive treatment (IPT) with SP will be introduced through antenatal clinics in close collaboration with reproductive health services. Expected outcomes: Reduced malaria incidence among pregnant mothers and increased birth weight of children, which will eventually lead to reduction of infant mortality rate. Application Form for Proposals to the Global Fund 36 Page 36 of 49 Objective V: To increase the number of pregnant mothers protected from malaria by 80% in high transmission areas Outcome/coverage indicators Baseline (Refer to Annex II) Year: 1 Targets Year 2: Year 3: Year 4: Year 5: % of pregnant women sleeping under bed net (LLITNs) N/A 30% (300,000) 50% (450,000) 70% (630,000) 90% (810,000) % of pregnant women who have taken IPT according to national guidelines N/A 30% (270,000) 50% (450,000) 70% (630,000) 90% (810,000) * Annual targets may be adjusted in line with baseline survey results a. Broad activities related to each specific objective and expected output (Describe the main activities to be undertaken, such as specific interventions, to achieve the stated objectives) (1 short paragraph per broad activity): • Procurement of LLITNs through public–private partnership. In order to sustain the project, a targeted subsidy system will be developed in which the private sector will provide the nets and ANC according to a colour-coded card system. A health visitor will register the pregnant women, enroll them in the program, distribute SP and assess their ability to afford a net. After the affordability assessment, the mother will be given a colored card according to whether she can pay for the net in full (red) or in part (yellow), or whether she should be provided with a net free of charge (green). • Introduction of IPT with SP through antenatal clinics in collaboration with the reproductive health directorat Objective V: To increase the number of pregnant mothers protected from malaria by 80% in high transmission areas Broad activities Process/Output Baseline indicators (indicate one per activity) (Refer to Annex II) Procurement % ofLL ITNs and procured out of distribution of estimated needs LLITNs (900,000 nets) Targets Responsible/ Implementing agency or agencies (Specify year) ? Year 1 2003 N/A 30% 50% SMOH, NMCP (300,000 (450,000 WHO, UNICEF, ) ) NGOs. . Application Form for Proposals to the Global Fund Page 37 of 49 Year 2 2004 Procurement N/A of SP % of tabs. Produced (2,700,000 out of estimated tabs) 30% 50% (900,000 (1,350,0 ) 00) FMoH, WHO, UNICEF, NGO and communities Impact evaluation of IPT 50% FMoH, WHO, academic institutes Report published and disseminated N/A 75% * Annual targets may be adjusted in line with baseline survey results 26. Objectives and expected outcomes (Describe the specific objectives and expected outcomes that will contribute to realizing the stated goal), (1 paragraph per specific objective): Objective VI: To increase the number of children <5 sleeping under the LLITNs by 20% every year: Children <5 years are more susceptible to malaria infection than adults. As children in Sudan go to sleep early, use of LLITNs may decrease malaria incidence among them. A public–private partnership will be encouraged to promote the importation of bednets, and to create demand for their use. Community-based organizations (e.g. women, youths) will be part of distribution. Expected outcomes: the use of LLITNs with proper case management will reduce malaria incidence among children <5 years, in addition to reducing the general mosquito population. Objective VI: To increase the number of children <5 sleeping under LLITNs by 20% every year Outcome/coverage indicators Baseline Targets (Refer to Annex II) Year: 1 Year 2: Year 3: Year 4: Year 5: % of households with children under 5 having at least one bednet (LLITNs) N/A 20% (1,200.000) 40% (2,400,000) 60% (3,600,000) 80% (4,800,000) * Annual targets may be adjusted in line with baseline survey results b. Broad activities related to each specific objective and expected output (Describe the main activities to be undertaken, such as specific interventions, to achieve the stated objectives) (1 short paragraph per broad activity): • Procurement of LLITNs through public–private partnership. A revolving system will be developed to sustain the project. Application Form for Proposals to the Global Fund 38 Page 38 of 49 • Promotion and distribution of LLITNs in collaboration with community-based organizations and NGOs. Objective VI: To increase the number of children <5 sleeping under ITNs by 20% every year Broad activities Process/Outpu Baseline t indicators (indicate one per activity) (Refer to Annex II) Targets (Specify year) ? Year 1 2003 Year 2 2004 Responsible/ Implementing agency or agencies Procurement and distribution of LLITNs % of LLITNs procured out of total estimated N/A 30% (1,500,000) 50% (2,400,000) SMOH, NMCP WHO, UNICEF, NGOs. . Impact evaluation of LLITNs on malaria incidence among <5 Report published and disseminated N/A 50% 75% FMoH, WHO, academic institutes *Annual targets may be adjusted in line with baseline survey results 27. Objectives and expected outcomes (Describe the specific objectives and expected outcomes that will contribute to realizing the stated goal), (1 paragraph per specific objective): Objective VII: To conduct cost-effective and evidence-based vector control activities where appropriate (environmental management, larviciding, indoor residual house spraying [IRHS]) • The use of insecticides will be limited in the first years to irrigated schemes (interim period), and then their use will be reserved for epidemic control. • In irrigated schemes and with the financial assistance of the Scheme Board, targeted IRHS can be applied. However, more effort will be directed for application to be effective. Application Form for Proposals to the Global Fund Page 39 of 49 • In urban areas and in areas where the breeding sites are limited and where the breeding sites cannot be eliminated by environmental measures, there is a place for larviciding using temephos. This will be helpful if there is community involvement. Expected outcome: • Vector density will be reduced, and hence with other measures the disease incidence will decrease. • Reliance on insecticide will be reduced by increasing the coverage with ITNs. Objective VII: To conduct cost-effective and evidence-based vector control activities where appropriate (Larviciding, indoor residual spraying) Outcome/coverage indicators Baseline Targets (Refer to Annex II) Year: Year 2: Year 3: Year 4: Year 5: % of target households sprayed (based on 2002 target) % of CBOs involved in malaria control N/A 80% 60% 40% 25% N/A 30% 50% 75% 100% *Annual targets may be adjusted in line with baseline survey results a. Broad activities related to each specific objective and expected output (Describe the main activities to be undertaken, such as specific interventions, to achieve the stated objectives) (1 short paragraph per broad activity): • • As insecticides are widely used in Sudan, a policy on rational use of insecticide needs to be developed. Insecticide to be used for IRHS in irrigated scheme must be procured. Application Form for Proposals to the Global Fund 40 Page 40 of 49 Objective VII: To conduct cost-effective and evidence-based vector control activities where appropriate (larviciding, indoor residual spraying) Broad activities IEC to raise community awareness Sensitization of irrigated schemes towards intermittent irrigation Procurement of insecticide (deltamethrine, temephos) Process/Output Baseline Targets Responsible/Implementin g agency or agencies (Specify year) Year 1 2003 Year 2 2004 % of CBOs involved in environmental management N/A 35% 60% NMCP, SMCP % of irrigated schemes adopting intermittent irrigation N/A 40%% 60% NMCP, SMCP % of quantities procured out of total requested N/A 60% 100% NMCP, SMCP * Annual targets may be adjusted in line with baseline survey results 27. Objectives and expected outcomes (Describe the specific objectives and expected outcomes that will contribute to realizing the stated goal), (1 paragraph per specific objective): Objective VIII: To upgrade the RBM capacity at national and state level It is obvious that RBM cannot succeed in Sudan without some investment in the entire health system. The decentralized health system will be strengthened through efforts to increase the capacity of state focal points for RBM to facilitate the achievement of the goals and objectives of RBM in Sudan. Partnership mechanisms will be strengthened between departments and programmes within health sector; with and between government sectors; with and between development agencies; with and between NGOs, the private and informal sectors; and with the community and traditional health providers. The malaria training centre Blue Nile Training and Research Institute (BNRTI), will upgraded and supported by a sub-centre in Juba. Serial training courses will be then conducted. Application Form for Proposals to the Global Fund Page 41 of 49 Expected outcome: the RBM capacity at local level will be improved and the training centre environment will be upgraded. Objective VIII: To upgrade the RBM capacity at national and state level Outcome/coverage indicators Baseline Targets (Refer to Annex II) Year: Year 2: Year 3: Year 4: Year 5: Malaria training centres set up or updated (at Wad Medani and Juba) N/A 40% 75% 100% 100% % of states with structure for RBM partnership N/A 50% (13) 100% (26) 100% (26) 100% (26) Proportion of states performing as required by the NMCP N/A 50% (13) 75% (20) 100% (26) 100% (26) * Annual targets may be adjusted in line with baseline survey results c. Broad activities related to each specific objective and expected output (Describe the main activities to be undertaken, such as specific interventions, to achieve the stated objectives) (1 short paragraph per broad activity): • • • Expansion of the RBM support system in 13 states not yet having such a system in the southern and western part of the country; review and address of human resources development, transport and communication issues. Improvement of training environment in malaria centers Monitoring and evaluation of progress towards RBM Application Form for Proposals to the Global Fund 42 Page 42 of 49 Objective VIII: To upgrade the RBM capacity at national and state level Broad activities indicators Baseline (indicate one per activity) (Refer to Annex II) Targets (Specify year) Year 1 2003 Year 2 2004 Responsible/Implementin g agency or agencies Develop subcentres for the Blue Nile Research and Training Institute (BNRTI) in Juba Juba sub-centre developed as planned N/A 50% 100% NMCP, WHO, UNICEF Upgrade the BNRTI to be able to accommodate more participants (library, rest rooms, laboratories) BNRTI meets required criteria N/A 50% 100% NMCP, WHO, UNICEF Conduct short courses on malaria epidemiology, planning for vector control and integrated vector management (total of 225) % of personnel trained out of total target N/A 20% (45) 60% (135) NMA, WHO, UNICEF, BNRTI Ensure good communication between state and federal level % of states with regular communication with the NMCP N/A 40% (10) 75% (20) FMOH, WHO and UNICEF Encourage the use of Healthmapper at state level with provision of computers and internet connection % of states using Healthmapper N/A 40% (10) 75% (20) NMCP, WHO, UNICEF Identify focal person for each states with support % of states focal points supported N/A 75% 100% NMCP, WHO, UNICEF Application Form for Proposals to the Global Fund Page 43 of 49 Monitor progress Evaluate activities Supervisory visits conducted and Reports received N/A 80% 100% Evaluation completed and report disseminated 0 100% 100% NMCP, All partners NMCP, Partners * Annual targets may be adjusted in line with baseline survey results 28. Describe how the component adds to or complements activities already undertaken by the government, external donors, the private sector or other relevant partner: (e.g., does the component build on or scale-up existing programs; does the component aim to fill existing gaps in national programs; does the proposal fit within the National Plan; is there a clear link between the component and broader development policies and programs such as Poverty Reduction Strategies or Sector-Wide Approaches, etc.), (Guidelines para. III.41 – 42),(2–3 paragraphs): • • • As an integral part of the Sudan strategic plan and in line with the Sudan RBM objectives, the primary aim of this component is to conduct targeted actions to scale up evidence-based cost-effective interventions to reduce malaria burden in Sudan (northern and southern parts). This component is arranged by the National Malaria Control Program (NMCP) in collaboration with WHO, UNICEF, NGOs and other partners aiming to accelerate the implementation of the strategic plan to RBM in Sudan. Resources requested from the GFTAM will fill the existing gaps in national resources and funding from the international donors. Governmental component: This is calculated from the actual total sum released by the government (Ministry of Finance). The annual budget allocated for malaria is used for the following: • Salaries, for health and non-health personnel working in the national and state malaria control programs • Maintenance of vehicle, buildings, furniture • Running cost of the program • New construction and rehabilitation of the old buildings, e.g. Sennar Training Center (STC) and Blue Nile Research and Training Institute Application Form for Proposals to the Global Fund 44 Page 44 of 49 • Transportation for field work • Wages for permanent seasonal laborers (Gambia project). Partners' component: This is calculated from the annual and biannual contributions of the current partners. Partners who have had direct contributions to the program for the previous three years are WHO and UNICEF. Estimated resource gap is the result of the difference between the total resource requirements and the estimated available resources. 29. Briefly describe how the component addresses the following issues (1 paragraph per item): 29.1. The involvement of beneficiaries such as people living with HIV/AIDS: The beneficiaries include the general public with particular emphasis high-risk groups (pregnant women and children < under 5 years), so activities are closely linked with the issue of community participation, as below. 29.2 Community participation: The NMCP and partners are aware of the value of community involvement in malaria control, as a safeguard for the sustainability of control activities. Strategy, specific objectives and activities have been set within the national RBM, to increase community awareness about the socioeconomic impact of malaria and control measures for active community participation in malaria prevention and control. Main activities include: raising the awareness of community leaders, conducting health education sessions targeting special groups (mass media personnel, teachers, etc.), “malaria weeks”. Activities related to raising community awareness are incorporated within the activities for strategic directions of RBM in Sudan. Community-based organizations will play an important role in the advocacy for, procurement and distribution of ITNs. The community should also have the right disposition and capacity to adopt desired practices in a sustainable manner. Caregivers in the community should be able to recognize cases of malaria in the home and provide correct treatment, including referrals as indicated. Application Form for Proposals to the Global Fund Page 45 of 49 29.2. Gender equality issues (Guidelines paragraph IV.53): Some strategies and activities in the national strategic plan for RBM in Sudan included in this component promote balance among men and women in allocation of opportunities and in access to services. Training opportunities and eligibility for positions are equally open for both sexes. In addition, there is the home management activity (the majority of caregivers in Sudan are women) and IPT for pregnant women (which includes training of midwives and traditional birth attendants). 29.3. Social equality issues (Guidelines paragraph IV.53): The interventions cover both northern Sudan and some of the most underserved areas in southern part of the country. To increase coverage for malaria treatment and prevention, special attention will be given to the most deprived areas in terms of workforce and service availability. In such areas, the capacity of non-health workers such as teachers and informal treatment outlets will be strengthened to provide proper information on malaria treatment. In areas of civil strife, essential drug kits will be distributed through partner NGOs. 29.5. Human resources development: Planning and conducting training at all levels as necessary are well addressed in this component. This will help to ensure that health personnel are available in sufficient quantities at all levels with skills and capacities to facilitate control of malaria. The Blue Nile Research and Training Institute will be improved, and its capacity increased, and a new training center in the south (Juba) will be established. 29.6. For components dealing with essential drugs and medicine, describe which products and treatment protocols will be used and how rational use will be ensured (i.e. to maximize adherence and monitor resistance), (Guidelines para. IV.55), (1–2 paragraphs): Summary of malaria treatment policy in Sudan (which is being revised according to WHO recommendations): a. Simple malaria (not complicated) 1st – line treatment: chloroquine 2nd –- line treatment: sulphadoxine pyrimthmine 3rd – line treatment: quinine. b. Severe and complicated malaria: - Quinine infusion - Artemether injections Activities to ensure adherence of prescribers (specialists, general practitioners, medical assistants, assistant pharmacists) to the national protocol and guidelines include workshops, national training activities, development and distribution of educational materials, and coordination and collaboration with the Federal Directorate General of Pharmacy. Application Form for Proposals to the Global Fund 46 Page 46 of 49 Drug sensitivity monitoring is being carried out through 10 permanent sentinel posts in different strata to monitor chloroquine and SP efficacy. SECTION V – Budget information 30. Indicate the summary of the financial resources requested from the Global Fund by year and budget category, (Refer to Guidelines paragraph V.56 – 58): Table V.30 Resources Year 1 Year 2 Year 3 Year 4 Year 5 Total needed (USD) (Estimate) (Estimate) (Estimate) 74,400 74,400 74,400 74,400 74,400 Human 372,000 Resources 234,000 50,000 45,000 45,000 Infrastructure/ 280,000 654,000 Equipment 406,656 673,197 223,200 191,000 193,200 1,687,253 Training/ Planning 2,375,000 2,220,000 2,265,000 2,170,000 2,215,000 Commodities/ 11,245,000 Products 3,016,100 3,216,100 3,050,000 3,000,000 3,000,000 Drugs 15,282,200 294,000 Monitoring and Evaluation Administrative 600,000 Costs 0 Other 174,000 174,000 184,000 174,000 1,000,000 600,000 600,000 600,000 600,000 3,000,000 0 0 0 0 0 Total 7,191,697 6,436,600 6,264,400 6,301,600 33,240,453 7,046,156 The budget categories may include the following items: Human Resources: Consultants, recruitment, salaries of front-line workers, etc. Infrastructure/Equipment: Building infrastructure, cars, microscopes, etc. Training/Planning: Training, workshops, meetings, etc. Commodities/Products: Bednets, condoms, syringes, educational material, etc. Drugs: ARVs drugs for opportunistic infections, TB drugs, anti-malaria drugs, etc. Monitoring & Evaluation: Data collection, analysis, reporting, etc. Administrative: Overhead, program management, audit costs, etc Other (please specify): Application Form for Proposals to the Global Fund Page 47 of 49 30.1. For drugs and commodities/products, specify in the table below the unit costs, volumes and total costs, for the FIRST YEAR ONLY: Table V.30.1 Item/unit Unit cost Volume Total cost (USD (specify (USD) measure) Chloroquine Syrup 50mg/ 5ml 1 / Bottle 1,500,000 1,500,000 Chloroquine Tabs 150mg/Tabs 7/1000 Tablets 15,000 cont. 105,000 Quinine Inj 300/ml (2ml ampls) 10,000 boxes 120,000 30000 boxes 91,000 7813 cont. 200,000 Pimaquine 15 mg Tabs 12/100 Ampouls 31/1000 Tablets 26.5/1000 Tablets 6/1000 Tabs IV fluids Bed nets(Permanent) Educational materials 1/bottle 4/ net 0.5/ copy 1,000,000 500,000 nets 74,000 Quinine Tabs 300 mg Tabs Sulfadoxine-Pyremethamine Tabs 15 cont. 100 1,000,000 2,000,000 30,000 30.2. In cases where Human Resources (HR) is an important share of the budget, explain to what extent HR spending will strengthen health systems capacity at the patient/target population level, and how these salaries will be sustained after the proposal period is over (1 paragraph): Human resources budget is about 1.1% out of the total 31. If you are receiving funding from other sources than the Global Fund for activities related to this component, indicate in the Table below overall funding received over the past three years as well as expected funding until 2005 in US dollars (Guidelines para. V.62): Table V.31.1 1999 Domestic (public in million ) External (in million) Total (in million) 2000 1.2 2001 2.2 2002 1.4 2003 1.4 2004 1.4 2005 1.4 1.0 2.312 1.27 0.5 0.5 0.5 2.2 4.512 2.67 1.9 1.9 1.9 Application Form for Proposals to the Global Fund 48 Page 48 of 49 Please note: The sum of yearly totals of Table V.31.1 from each component should correspond to the yearly total in Table 1.b of the Executive Summary. For example, if Year 1 in the proposal is 2003, the column in Table 1.b labeled Year 1 should have in the last row the total of funding from other sources for 2003 for all components of the proposal. 32. Provide a full and detailed budget as attachment, which should reflect the broad budget categories mentioned above as well as the component’s activities. It should include unit costs and volumes, where appropriate (Attachment VIII) 33. Indicate in the Table below how the requested resources will be allocated to the implementing partners, in percentage (Refer to Guidelines para. V.63): Table V.33 Resource allocation to implementing partners* (%) Government Year 1 Year 2 Year 3 (Estimate) Year 4 (Estimate) Year 5 (Estimate) Total (average) 55% 55% 50% 50% 50% 52% NGOs / CommunityBased Org. Private Sector 12% 12% 18% 18% 18% 16% 10% 10% 10% 10% 10% 10% People living with HIV/ TB/ malaria Academic / Educational Organisations Faith-based Organisations Others 10% 10% 10% 10% 10% 10% 5% 5% 5% 5% 5% 5% 2% 2% 2% 2% 2% 2% 5% 5% 5% 5% 5% 5% 100% 100% 100% 100% 100% 100% Total Total in USD If there is only one partner, please explain why. Application Form for Proposals to the Global Fund Page 49 of 49
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