Clinical Science: Distinguishing Fads, Myths and Evidence Gregory L. Lof Stephen M. Camarata Ph.D., CCC-SLP Ph.D., CCC-SLP Department Chair/Professor Professor Outline of Our Talk • Introduction • What is a Skeptic? • Questionable Treatments • Tools for Skeptical Thinking • On the Horizon • Discussion Introduction Introduction • Speech-Language Pathology: clinician driven • Ongoing need for evidence to guide treatment • Unfortunate history of missteps and treatment “fads” that are subsequently “debunked” (FC) Introduction Introduction • What can be learned from our mistakes? • How do we prevent this from happening again? • Is there a process going forward that will ensure that questionable or “fad” treatments are not adopted? • Answers from broad field of treatment including medicine and related disciplines • NOTE: not unique to SLP! Skepticism Our best way to defend against quackery, pseudoscience, and questionable practices. What is a Skeptic? A skeptic is a person who has a questioning attitude or has some degree of doubt regarding claims that are elsewhere taken for granted. The word skepticism can characterize a position on a single claim, but more frequently it describes a lasting mind-set. Skepticism is an approach to accepting, rejecting, or suspending judgment on new information that requires the new information to be well supported by evidence. The Skeptics’ Balancing Act The Skeptics’ Balancing Act A ruthlessly skeptical scrutiny of all ideas, old and new. An openness to new ideas, no matter how bizarre or counterintuitive Sagan, 1996 Being a Skeptic “Some people believe that skepticism is the rejection of new ideas, or worse, they confuse “skeptic” with “cynic” and think that skeptics are a bunch of grumpy curmudgeons unwilling to accept any claim that challenges the status quo.” Shermer, 2010 Being a Skeptic “This is wrong. Skepticism is a provisional approach to claims. It is the application of reason to any and all ideas — no sacred cows allowed. In other words, skepticism is a method, not a position.” Shermer, 2010 Being a Skeptic “Ideally, skeptics do not go into an investigation closed to the possibility that a phenomenon might be real or that a claim might be true. When we say we are “skeptical,” we mean that we must see compelling evidence before we believe.” Shermer, 2010 Questionable Treatments Past Present Future Questionable Treatments Past Questionable Treatments Present Nonspeech Oral Motor Exercises Questionable Treatments Future Questionable Treatments Past Tools for Skeptical Thinking Tools for Skeptical Thinking These ideas can help you remain appropriately skeptical when encountering therapeutic techniques so you can analyze the purported findings. Sagan, 1996 Tools for Skeptical Thinking Independent Confirmation Can other clinician/researchers come up with the same findings? Sagan, 1996 Tools for Skeptical Thinking Encourage Debate on the Evidence There must be open and free dialogue in order for the science of new techniques to be evaluated. A few of the journals are now encouraging such debates. This debate is NOT personal, it is about data Sagan, 1996 Tools for Skeptical Thinking Believe Data not “Experts” It is important to look at the data…not just the words from “authorities.” We need the data that show efficacy. Sagan, 1996 Tools for Skeptical Thinking Be Skeptical of Anecdotes and Testimonials Don’t let testimonials and nonscientific findings sway you… these may be interesting and may lead us to ask important questions, but without proper data all claims are meaningless. Sagan, 1996 Tools for Skeptical Thinking Be Skeptical of Anecdotes and Testimonials Why do so many webpages that promote a specific treatment always have a section for “Testimonials” but few have a section on “Research”? Sagan, 1996 Tools for Skeptical Thinking A Case Study is NOT Experimental A case study cannot and never has been a methodology for explaining causeeffect relationships. Sagan, 1996 Tools for Skeptical Thinking Follow the Scientific Methodology Including true peer-review Sagan, 1996 Tools for Skeptical Thinking Spin More than One Hypothesis If you observe something working, try to determine WHY it works. The WHY is often as important as the IF IT WORKS. Perhaps why something works has nothing to do with the treatment itself. Sagan, 1996 Tools for Skeptical Thinking Every Link in the Argument Chain Must Work When following the logic of the argument ALL of the pieces must fit together, not just some. We must always look at all aspects, and if there is one weak or broken link, then the entire theory may not be supported Is the explanation too simplistic to account for the complicated constellation of behaviors? Sagan, 1996 Tools for Skeptical Thinking Don’t Ignore the Misses and Only Count the Hits Look at all the evidence, not just some. For example, only 1 study shows that NSOME works, but many many show it does not work. Look at the misses! We cannot overlook the misses and only concentrate on the hits. Sagan, 1996 Tools for Skeptical Thinking If it Sounds too Good to be True, It Probably is Not True One therapeutic technique cannot possibly work for all different types of disorders. Be careful of grandiose claims of effectiveness. There is no such thing as a “cure-all.” Sagan, 1996 Tools for Skeptical Thinking If it Sounds too Good to be True, It Probably is Not True Tools for Skeptical Thinking Be Careful of the Popular Press Just because something is in the popular press does not mean that it has been scientifically tested. Only information from peer-reviewed reputable journals can be believed, and then appropriate skepticism must still be applied. Be careful of the internet, promotional websites, selfpublished books, and news stories on TV. Sagan, 1996 Tools for Skeptical Thinking Nonstandard Treatments Rarely Look Outlandish Promoters will often use scientific sounding terms and quotes or they may misquote from scientific references. Be wary of pseudoscientific jargon. Sagan, 1996 Tools for Skeptical Thinking Don’t Let Desperation Cloud Our Judgment Many times therapists, clients, and parents are desperate for changes. Sagan, 1996 Tools for Skeptical Thinking Evoking the Past Just because something has been done a long time does not make it legitimate. Just because someone has been doing it for a long time does not make it effective. Just because “Van Riper” said it does not automatically make it justifiable. Sagan, 1996 Moving Forward: BS* Detector On the Horizon: Interactive Metronome (IM) * Be Skeptical Video From IM Website Interactive Metronome: Claims • “Brain Based” • Neural Plasticity • “Quick Fix” • “Magic Bullet” Interactive Metronome: What Does it Treat? • • • • • • • • • ADHD Autism/ASD “Sensory Integration Deficit” LANGUAGE PROCESSING Asperger Syndrome Cerebral Palsy Stroke Head Trauma Parkinson’s Interactive Metronome: Take a Step Back! • Does it make sense that hand clapping and foot tapping will “treat” all these conditions? • How does IM relate to speech and language? • Should SLPs be including IM in treatment? Interactive Metronome: Neural Plasticity • All learning is associated with neural plasticity: Learning changes the brain • Learning “beats” does not engage neural plasticity more than learning words (or any other speech and language forms) • Finger tapping in primates (Merzenich) • Proximal and distal effects Interactive Metronome: What Evidence is Needed for SLPs to Adopt IM? • Not Testimonials or YouTube “Stories” • Not Press Releases or TV News Stories • Not “Research” from IM website (showing “deficit” is not evidence for treatment!) • Single Subject Designs (Weighted Vest Literature) • Fair Treatment Studies NOTE: There are Current EBP Supported Treatments for Target Populations! • Use these approaches UNTIL IM comes forward with data that show better and/or additional effects • For example, PRT (Koegel & Koegel, 2009) in Autism Use your BS Detector When New Cures are Offered • What is the evidence base? • How does it compare to other treatments? • What conditions does it claim to treat? • What is being taught? Why? What is the patient learning? • How does this translate to functional outcomes? • Seeing isn’t necessarily believing! Some Good Reading Discussion Clinical Science: Distinguishing Fads, Myths and Evidence Gregory L. Lof Stephen M. Camarata Ph.D., CCC-SLP Ph.D., CCC-SLP Department Chair/Professor Professor
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