Nucleic Acids in Wonderland

th
The 12 Nucleic Acids Forum
Royal Society of Chemistry, Burlington
House, London,
th
Friday 15 July 2016
Morning
Afternoon
9:30 – 10:20 am Registration (Library Annexe) with tea/coffee and
poster set up (Science Room)
13:00 – 14:45 Buffet Lunch and Main Poster session (Fish and
Science Rooms)
10:20 – 11:30 Session 1 (Library) – Chair: Anastasia Callaghan
14:45 – 15:45 Session 3 (Library) – Chair: Christoph Baumann
Welcome message from the Nucleic Acids Group – David Lilley
Martin Wilkinson – 3.8Å cryo-EM structure of the RecBCD
Helicase/Nuclease complex
Anna Dysko – Synthesis and properties of oligonucleotides
containing triazole backbone linkages for therapeutic applications
Sarah Gurung – Crystallographic & Biophysical Studies of DNA Imotifs
Chistopher Toseland – Nuclear Myosin VI - Myosin can bind DNA
Jack Phillips – RNA Arrays: A novel opportunity for RNA research
Fergus Poynton – Photochemically active DNA-Intercalating
Complexes – Insights by Combining Crystallography and Transient
Spectroscopy
11:30 – 12:00 Coffee Break (Library Annexe) and poster set up
(Science Room)
15:45 – 16:15 Coffee Break (Library Annexe)
12:00 – 13:00 Session 2 (Library) – Chair: David Rusling
David Rusling – Functionalising Designer DNA Crystals with a
Triple-Helical Veneer
Benedict Tan – Length heteroplasmy of conserved sequence block 2
in human mitochondrial genomes and the effect on RNA polymerase
POLRMT in vitro
16:15 – 17:15 Session 4 (Library) – Chair: Julia Kenyon
Lin Huang – The kink turn in the organization of the architecture of
RNA, and as a building block in nano-engineering
Tilemachos Kosmidis – Defining the Structural Determinants of
Transcriptional Fidelity in an Expanded Genetic Alphabet
Mikiembo Kukwikila – Click-mediated DNA Ligation for One-pot
Gene Synthesis
Ha Phuong Nguyen – Synthesis of Chemical Tools for Targeted
Epigenetic Modifications
17:15 – 17:20 Award of Prizes
17:30-18:30 Wine Reception (Fish and Science Rooms)