th The 12 Nucleic Acids Forum Royal Society of Chemistry, Burlington House, London, th Friday 15 July 2016 Morning Afternoon 9:30 – 10:20 am Registration (Library Annexe) with tea/coffee and poster set up (Science Room) 13:00 – 14:45 Buffet Lunch and Main Poster session (Fish and Science Rooms) 10:20 – 11:30 Session 1 (Library) – Chair: Anastasia Callaghan 14:45 – 15:45 Session 3 (Library) – Chair: Christoph Baumann Welcome message from the Nucleic Acids Group – David Lilley Martin Wilkinson – 3.8Å cryo-EM structure of the RecBCD Helicase/Nuclease complex Anna Dysko – Synthesis and properties of oligonucleotides containing triazole backbone linkages for therapeutic applications Sarah Gurung – Crystallographic & Biophysical Studies of DNA Imotifs Chistopher Toseland – Nuclear Myosin VI - Myosin can bind DNA Jack Phillips – RNA Arrays: A novel opportunity for RNA research Fergus Poynton – Photochemically active DNA-Intercalating Complexes – Insights by Combining Crystallography and Transient Spectroscopy 11:30 – 12:00 Coffee Break (Library Annexe) and poster set up (Science Room) 15:45 – 16:15 Coffee Break (Library Annexe) 12:00 – 13:00 Session 2 (Library) – Chair: David Rusling David Rusling – Functionalising Designer DNA Crystals with a Triple-Helical Veneer Benedict Tan – Length heteroplasmy of conserved sequence block 2 in human mitochondrial genomes and the effect on RNA polymerase POLRMT in vitro 16:15 – 17:15 Session 4 (Library) – Chair: Julia Kenyon Lin Huang – The kink turn in the organization of the architecture of RNA, and as a building block in nano-engineering Tilemachos Kosmidis – Defining the Structural Determinants of Transcriptional Fidelity in an Expanded Genetic Alphabet Mikiembo Kukwikila – Click-mediated DNA Ligation for One-pot Gene Synthesis Ha Phuong Nguyen – Synthesis of Chemical Tools for Targeted Epigenetic Modifications 17:15 – 17:20 Award of Prizes 17:30-18:30 Wine Reception (Fish and Science Rooms)
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