Think about the machine that rolled the flat waffle sheets into cones: 1. If we changed the shape of the roller, would it still work? 2. What requires less effort (energy), letting the machine do the rolling or having people roll each cone by hand? 3. What is faster, letting the machine do the rolling or having people roll each cone by hand? 4. Is the machine affected in any way each time it rolls a cone? 5. We learned that when the cones cool down, they harden. Would the machine still work if it was put inside a freezer? Enzymes 1B.1) SWBAT predict what will happen to an enzyme catalyzed reaction when we change the temperature and explain their reasoning 1B.2) SWBAT explain the effect of enzymes on energy of activation, equilibrium, and the rate at which equilibrium is attained 1B.3) SWBAT understand that the enzyme-substrate interaction is very specific like a lock and key fit LEARNING OBJECTIVE: We will learn how enzymes affect chemical reactions. What is a catalyst? LEARNING OBJECTIVE: We will learn how enzymes affect chemical reactions. What is a catalyst? A catalyst is any substance that can affect the rate (speed) of a chemical reaction. A catalyst is not changed or used up during the reaction. LEARNING OBJECTIVE: We will learn how enzymes affect chemical reactions. What is an enzyme? An enzyme is a catalyst made of proteins. Enzymes can affect the rate chemical reactions in living things. Enzymes speed up biochemical reactions by lowering the activation energy of reactions that would normally happen anyway. LEARNING OBJECTIVE: We will learn how enzymes affect chemical reactions. How do enzymes work? Enzymes have specific shapes that influence how they function and interact with other molecules. Enzyme Molecule The enzyme will function better the more precisely it fits with the molecule. LEARNING OBJECTIVE: We will learn how enzymes affect chemical reactions. How do enzymes work? Enzyme Enzymes can be reused, so they can work on multiple molecules. Molecule Molecule LEARNING OBJECTIVE: We will learn how enzymes affect chemical reactions. What affects how enzymes work? Shape Each enzyme has a specific shape to work correctly. Anything that changes that shape will affect how the enzyme works. LEARNING OBJECTIVE: We will learn how enzymes affect chemical reactions. What affects how enzymes work? Temperature Most enzymes have an optimum (ideal) temperature where they work the best. Beyond the optimum temperature, the enzyme begins to change shape or break apart, so it does not work as well (or at all). LEARNING OBJECTIVE: We will learn how enzymes affect chemical reactions. What affects how enzymes work? LEARNING OBJECTIVE: We will learn how enzymes affect chemical reactions. What affects how enzymes work? pH pH is a measure of whether a substance is acidic, neutral, or basic (0‐14) All enzymes have an optimal pH where they function the best. Many enzymes function the best at a neutral pH (of 7), although there are exceptions. Exit Slip 1B.1) There are bacteria called thermophiles (they like heat). The record for life growing at high temperatures is 235°F. Their enzymes have evolved to function at these temperatures. Would their enzymes work if you placed the bacteria in ice water? 1B.2) You can buy hydrogen peroxide in the pharmacy. Hydrogen peroxide undergoes a chemical reaction to break down into water and oxygen. If you pour it on your skin, nothing happens. If you pour it on a cut, it starts bubbling right away (because oxygen is being produced). What could have been released from your cells when you got a cut that would speed up the reaction? How is the reaction sped up? 1B.3) Why can’t an enzyme that copies DNA also copy proteins? http://www.divediscover.whoi.edu/hottopics/bacteria.html Enzymes: Fun Facts Enzymes work quickly—about 1000 substrates are taken in and converted every second.
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