Communicating Genetics to Undergraduates and Producers Debra K. Aaron, Ph.D. Animal Breeding & Genetics, Statistics; Sheep University of Kentucky Communicating genetics Teach in an understandable and usable form Animal Science Students Livestock Producers Others in Livestock Industry Communicating Genetics to Undergraduates and Producers 1 What do we teach? 2 How do we teach it? 3 What are our challenges? 4 How do we meet them? What do we teach? • Undergraduate courses – Introductory animal sciences – Animal breeding and genetics ASC 362 • The study of inheritance in animals–animal genetics • The application of principles of animal genetics to farm animal improvement–animal breeding Course Description • Fundamental principles of genetics and statistics as applied in selection and mating systems to make genetic improvements in farm animals. Involves traditional discussion of Mendelian, population and quantitative genetics and their application. Includes introduction to some genetic engineering techniques and their application in the improvement of livestock and poultry. Learning Objectives 1. Summarize history of modern livestock breeding. 2. Describe important concepts of Mendelian inheritance. 3. Use probability rules in analysis of genetic problems. 4. Characterize basic genetic model and explain how different types of gene action contribute. Learning Objectives 5. Describe importance of heritability to selection and management. 6. Differentiate between types of mating systems, calculate inbreeding and relationship coefficients and estimate heterosis. Learning Objectives 7. Apply principles of quantitative genetics to selection and mating systems. 8. Use EBV/EPD to rank and select potential sires and dams. 9. Explain how genomic data can be used in genetic improvement. Course Outline I. Introduction II. Mendelian Inheritance III. Genetic Abnormalities in Farm Animals IV. Population Genetics V. Types of Traits Course Outline VI. The Genetic Model for Quantitative Traits VII. Statistics and Their Application to Quantitative Traits VIII.Heritability and Repeatability Course Outline IX. Principles of Selection for Quantitative Traits X. Genetic Prediction XI. Large-Scale Genetic Evaluation XII. Systems of Mating Mendelian versus Molecular Tradition versus Technology Branches of Animal Genetics Genetics Mendelian Population Quantitative Molecular Transmission of genetic material from one generation to the next. Mendelian genetics in populations; Hardy-Weinberg Law is foundation; limited to qualitative traits influenced by small number of genes. Quantitative traits influenced by many genes; based on principles of Mendelian and population genetics combined with statistical concepts. Molecular structure and function of genes. “… all these things need to be covered first. Then and only then can we introduce students to genomics. You don’t start a course by showing students the most complex known example of genetic variation. You start with simple examples and basic concepts then work your way up to the more difficult examples.” L. A. Moran, Professor of Biochemistry 2012 Genomic selection sounds scary to some of us, but .... … it actually just extends the traditional approach to selection. Information Included in Genomic-Enhanced EBVs Progeny Genomic Results Pedigree Individual EBVs (EPDs) What do we teach? • Undergraduate courses – Introductory animal sciences – Animal breeding and genetics – Production or science What do we teach? • Undergraduate courses – Introductory animal sciences – Animal breeding and(or) genetics – Production (Beef, Dairy, Sheep, Swine, Poultry) – Advanced genetics (molecular, genetic engineering) What do we teach? • Livestock (sheep) producers – Genetic principles as they apply to livestock improvement Selection Mating systems – Changing technology Animal evaluations (EBVs) Genomics What do we teach? • Livestock (sheep) producers – Need-dictated – Producer-driven – Applied in nature Small flocks Beginning producers – Not highly technical – Rarely genomic-oriented Communicating Genetics to Undergraduates and Producers 1 What do we teach? 2 How do we teach it? How do we teach it? • Undergraduates – Traditional lectures/labs • Notetaking • Problem solving • Homework, quizzes, exams • Illustrations, demonstrations and examples How do we teach it? • Undergraduates – Emphasize active learning – Hands-on experience with simulation Scheduling Round (lambing year) 1 (2013) 2 (2014) 3 (2014) 4(2015) 5 (2016) Results out* Mon, Mar 18 Wed, Mar 27 Fri, Apr 5 Mon, Apr 15 Wed, Apr 24 Reference sire team Decisions elected* in* Wed, Mar 20 Mon, Mar 25 Fri, Mar 29 Wed, Apr 3 Mon, Apr 8 Fri, Apr 12 Wed, Apr 17 Mon, Apr 22 n/a n/a *Due 8:00 pm EDT. CyberSheep Manual, Page 13 Potential Rewards Play of CyberSheep worth 50 points On-time submission contributes 10 points toward final grade (40 points total) Evaluation form contributes 10 points Bonus points On-time submissions and completion of final assignment generate 10 points Most net income generates 10 points Maximum genetic response generates 10 points Assignments worth 35 to 50 points Final assignment due last day of class Fun CyberSheep Round 3 Results 2016 Earnings leader: Team #7 Greatest genetic change: Team #18 Teams #1, 17 and 21 eliminated spider allele! How do we teach it? • Livestock (sheep) producers – Producer schools Eweprofit I, II and III Lambing School – Field days Sheeprofit Day (44th annual) How do we teach it? • Livestock (sheep) producers – Participation – Illustration – Demonstration PP 1/2 WD 3/4 WD 7/8 WD 15/16 WD Purebred White Dorper ram and ewe lambs produced as part of grading-up project How do we teach it? • Livestock (sheep) producers – Producer schools Eweprofit I, II and III Lambing School – Field days Sheeprofit Day (44th annual) – Local meetings – KSWPA annual meeting – Publications Communicating Genetics to Undergraduates and Producers 1 What do we teach? 2 How do we teach it? 3 What are our challenges? What are our challenges? • Animal science students – Numeracy – Thinking skills – Study habits – Problem solving – Place in curriculum – Rigor – Livestock experience Diversity Undergraduates • Gender – 79% females • Career objectives – Veterinary medicine (59%) – Food animal production ( less than 5%) • Species of interest – Companion animals (50%) – Equine (24%) – Food-producing animals (20%) Peffer, NACTA J., March 2011, Undergraduates Female (80%) Urban, non-farm backgrounds No livestock experience Little 4-H, FFA participation Pre-veterinary medicine Equine and small animal Undergraduates • Discipline perceived to be most valuable to learn – Nutrition – Reproduction – Behavior • Genetics not perceived as valuable Peffer, NACTA J., March 2011, “Genetics are not an important economic driver on my ranch unless it causes a wreck.” Pete Marble, 1980 What are our challenges? • Livestock (sheep) producers – Production goals – Breeds – Flock size – Age – Education – Experience Diversity Tradition Sheep Producers • Older (retired or close to retirement) • Educated • Couple • Naïve • Hobby • Small flocks (25 or fewer ewes) Sheep Producers • • • • • • • • Young (35 to 40 yr) Varied education Progressive Open-minded Naïve Eager for information Serious about making money Large flocks (100+ ewes) Sheep Producers • Young females (30 to 35 yr) – Stay-at-home moms – Educated – Organic – Natural – Fiber – Exotics – Very small flocks (12 or fewer ewes) Sheep Producers • Male (65%) • 45 yr or older (84%) • Diverse education backgrounds – 33% high school graduates • Over 20 yr experience • Demographic differences by flock size Gardiner et al. (2012) The Next Generation Who will they be? Communicating Genetics to Undergraduates and Producers 1 What do we teach? 2 How do we teach it? 3 What are our challenges? 4 How do we meet them? How do we meet them? • Undergraduates – Increased exposure to food-animals – Greater emphasis on career opportunities – More hands-on experiences – Change in teaching philosophy and(or) methods of instruction – Better integration of genetic courses into curriculum How do we meet them? • Livestock (sheep) producers – Know clientele and their needs How do we meet them? • Livestock (sheep) producers – Know clientele and their needs – Address basics first • Production goals • Recordkeeping • Selection • Mating plans – Be realistic Communicating genetics Teach in an understandable and usable form Animal Science Students Livestock Producers Others in Livestock Industry For students, the goal is to give them a stronger knowledge base to better understand the world as they integrate into their chosen careers. For producers, the goal is to help them better understand the application of genetics to livestock improvement and to prepare them for changing technologies. Communicating Genetics to Undergraduates and Producers Debra K. Aaron University of Kentucky
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