Physiology The cell is the basic unit of structure and function of all living things The cell is considered to be the smallest structure in biology that has all the properties of living things and an understanding of cells and the basics of cell structure and function is critical to making sense out of biology. Cell membrane. Cytoplasm. DNA. All cells have a phospholipid based cell membrane. The cell membrane is selectively permeable in that it allows some materials to pass into or out of the cell but not others. Cells are filled with a complex collection of substances in a water based solution. This substance is called cytoplasm. Across all cells there are a number of common features to all cell cytoplasm. For example all cells have ribosomes. Also, in all cells the first steps in cellular respiration take place in the cytoplasm. All cells contain DNA(2). In the simplest cells, the DNA is in one loop more loop like structures free in the cytoplasm. In some cells such as those making up our body the DNA is isolated from the cytoplasm in a special structure called a nucleus. Remember not all cells have a nucleus! This image shows a cell in an aquatic plant, Elodea. The clear strand at the tip of the arrow represents a 'conveyor belt' made of proteins that helps to move some of the cell's parts around the cell. Plasma, the liquid portion of the blood without the blood cells, makes up about 7 percent of body fluid. The intracellular compartment, the fluid located inside cells, makes up about 65 percent of body fluid. Intercellular fluid is the fluid in the potential spaces between cells in the various organs and tissues. Since the human body is mostly water, proper fluid balance is needed to sustain proper functions for kidneys and other organs as well as help flush waste from body. Electrolytes are minerals in your body that have an electric charge. They are in your blood, urine and body fluids. Maintaining the right balance of electrolytes helps your body's blood chemistry, muscle action and other processes. Sodium, calcium, potassium, chlorine, phosphate and magnesium are all electrolytes. You get them from the foods you eat and the fluids you drink. Levels of electrolytes in your body can become too low or too high. That can happen when the amount of water in your body changes. Causes include some medicines, vomiting, diarrhea, sweating or kidney problems. Problems most often occur with levels of sodium, potassium or calcium. Water intoxication, also known as hyper-hydration, water poisoning, or overhydration, is a potentially fatal disturbance in brain functions that results when the normal balance of electrolytes in the body is pushed outside of safe limits by overconsumption of water. First observable symptoms of water intoxication: headache, personality changes, changes in behavior, confusion, irritability, and drowsiness. These are sometimes followed by difficulty breathing during exertion, muscle weakness, twitching, or cramping, nausea, vomiting, thirst, and a dulled ability to perceive and interpret sensory information. Nearly all deaths related to water intoxication in normal individuals have resulted either from water drinking contests in which individuals attempt to consume large amounts of water, or long bouts of intensive exercise during which electrolytes are not properly replenished, yet excessive amounts of fluid are still consumed. Normal, physically, nutritionally and mentally healthy individuals have little reason to worry about accidentally consuming too much water. The two types of dehydration, chronic dehydration and acute dehydration, can be caused by many things. The most common are: flu, vomiting, diarrhea, blood loss, malnutrition, and plain old failure to replenish liquids lost from sweating and urination (Not drinking enough water). Many illnesses and diseases can trigger acute dehydration due to the increased body temperature and sweating that usually occur. This is why your doctor tells you to drink plenty of fluids when you are ill. Your body uses fluids to expel toxins as well as to keep your system flexible, lubricated and running smoothly. The initial signs and symptoms of mild dehydration in adults appear when the body has lost about 2% of it's total fluid. These mild dehydration symptoms are often (but not limited to): Thirst Loss of Appetite Dry Skin Skin Flushing Dark Colored Urine Dry Mouth fatigue or Weakness Chills Head Rushes Human homeostasis is derived from the Greek, homeo or "same", and stasis or "stable" and means remaining stable or remaining the same. The human body manages a multitude of highly complex interactions to maintain balance or return systems to functioning within a normal range. The kidneys are responsible for regulating blood water levels, re-absorption of substances into the blood, maintenance of salt and ion levels in the blood, regulation of blood pH, and excretion of urea and other wastes. When we talk about acid-base balance, we are referring to the pH balance (degree of acidity or alkalinity) of substances of the body. The symbol pH is used after numbers that measure the degree of the acidity or alkalinity of solutions. The acidity or the alkalinity of a solution is determined by the number of hydrogen ions (H + ) it contains. The blood is slightly alkaline, with a pH of 7.35 to 7.4. Any abnormality in the acid-base balance in the human body may lead to acidosis, which means the blood pH level is more acidic or a pH level less than 7.35. A second condition that may arise is called alkalosis, which means the pH level of the blood has too little acid or a pH level greater than 7.45. The normal average for pH balanced blood is 7.4. Either one of the acid-base imbalances may result in serious organ disorders. Symptoms of acidosis are not typically differentiated from diseases from which the body may be suffering. However, it may result in weakness, nausea or vomiting. Symptoms of alkalosis are more noticeable and include dizziness, light-headedness or a sense of numbing in feet or hands. Most people are not aware of the symptoms of either of these conditions; regular health checkups are necessary to avoid the complications associated with irregular acid-base balance of blood chemistry.
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