All available peanut components are needed for a complete risk assessment
Risk assessment with ImmunoCAP® Molecular Allergology
f 13 (peanut) + Ara h 1 + Ara h 2 + Ara h 3
f 13 + Ara h 2
Factors to consider:
f 13 + Ara h 9
• Sensitization
f 13 + Ara h 8
Risk for reaction
Risk for severe reaction
High risk for severe reaction
to several allergen components
• Local exposure
• Level of exposure
• Level of Specific IgE
PROTEIN GROUPS:
Storage proteins:
• Ara h 1
• Ara h 2
• Ara h 3
–Associated with severe reactions
–Stable to heat and digestion
PR-10 protein:
LTP:
• Ara h 8
• Ara h 9
–Associated with local reactions (e.g. OAS)
–Associated with both severe and local reactions
–Labile to heat and digestion
–Stable to heat and digestion
–Associated with allergy to birch and
–Associated with allergy to peach and peach
birch related tree pollens
related fruits
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PEANUT
Molecular Allergology
PEANUT
Molecular Allergology
Suspicion of peanut allergy – risk for severe reaction?
Recommended test profile:
Peanut (f 13) and Ara h 1 and Ara h 2 and Ara h 3 and Ara h 9* and Ara h 8*
results:
Peanut (f 13) + Ara h 1 / Ara h 2 / Ara h 3 + Ara h 9*
+
+
+
–
+
+
* According to local exposure
thermoscientific.com/phadia
+
Ara h 8*
–
Risk for severe
reactions to peanut
+
Risk for reactions
to peanut due to
cross-reactivity