PAPER 245 THE PRACTICE OF mE TRANSCENDENTAL MEDITATION AND TM-SIDID PROGRAMME REVERSES THE PHYSIOLOGICAL AGEING PROCESS MICHAEL TOOMEY, BRIAN PENNINGTON, 1 ROGER CHALMERS, and GEOFFREY CLEMENTS MERU Research Institute, Mentmore, Buckinghamshire, England 1Department of Biology, University of York, England Research completed September 1982. Participants in the Transcendental Meditation and TM-Sidhi programme were found to have an average biological age which was 7.2 years younger than their average chronological age of 31.8 years. Length of time practising the Transcendental Meditation and TM-Sidhi programme was found to be correlated with reduction in biological age.-EDITORS 1871 SCIENTIFIC RESEARCH ON THE TRANSCENDENTAL MEDITATION AND TM-SIDHI PROGRAMME , VOL. 3 A cross-sectional study was undertaken to evaluate the effects of the Transcendental Meditation and TMSidhi programme on the ageing process using a standard test of biological ageing, which involved measuremJnts of auditory threshold at 6kHz, near point of vision, and systolic blood pressure. The test was administered to 173 participants in the Transcendental Meditation and TM-Sid,hi programme (127 men, mean age 30.7 years, and 46 ladies, mean age 35.0 years). Scores showed that the mean biological age of the subjects was 7.2 years younger than their chronological age (p< .001). Furthermore, a significant correlation was found between the reduction in biological age and length of time practising the Transcendental Meditation and TM-Sidhi programme (p <. 001). Another measure of physiological ageing, functional age, was found to show a similar correlation with duration of practice (p< .001). Multiple regression analysis indicated that duration ofpractice of the Transcendental Meditation and TMSidhi programme was significantly predictive of improvement in systolic blood pressure (p<.001) and auditory threshold (p< .05). The findings support the hypothesis that the Transcendental Meditation and TM-Sidhi programme reverses the ageing process. INTRODUCIION Certain physiological variables change progressively over the course of adult life. These can serve as indicators of the rate at which ageing proceeds in .individuals and populations (Bourliere, 1970; Murray, 1951). Wallace, Dillbeck, Jacobe, and Harrington (1982), using the Adult Growth Examination (Morgan and Fevens, 1972), recently demonstrated that practitioners of the Transcendental Meditation and TMSidhi programme had significantly lower biological age scores compared to norms and to control subjects. The mean biological age of short-term practitioners of the Transcendental Meditation and TMSidhi programme was found to be 5 years younger than their chronological age, while that of the longterm subjects was 12 years younger. Furthermore, a significant correlation was found between length of time practising the Transcendental Meditation programme and younger biological age (r = - .46, N=84, p<.001). On the basis of their results, Wallace et al. suggest that the Transcendental Meditation and TMSidhi programme has the effect of reversing the ageing process. In support of this conclusion they cite many previous findings on the physiological and psychological changes that accompany the practice of these techniques (Orme-Johnson and Farrow, 1977; Chalmers et al., in press). The present study was conducted to examine further the relationship between length of time par- 1872 ticipating in the Transcendental Meditation and TMSidhi programme and biological age, and to extend the research of Wallace et al. by investigating this relationship in subjects who were on average some 20 years younger than those participating in Wallace's study. Multiple regression analysis was used to test the hypothesis that the changes produced by the Transcendental Meditation and TM-Sidhi programme in the physiological variables assessed constitute an actual reversal of the usual results of ageing. METHODS SUBJECTS-A total of 173 people were examined, 127 men and 46 ladies. The mean age of the subjects was 30.7 years for the men (range 18.8 to 68.7 years), and 35.0 years for the ladies (range 21.5 to 66.3 years). The mean duration of participation in the Transcendental Meditation programme was 6.5 years for the men (range 0.4 to 14.0 years), and 6.5 years for the ladies (range 0.5 to 15.8 years). The majority of the people in the study had learnt the TM-Sidhi programme, a set of advanced meditation procedures practised in addition to the Transcendental Meditation technique. The mean length of time of participation in the TM-Sidhi programme was 2.1 years for the men (range of 0 to 4.3 years), and 2.3 years for the ladies (range of 0 to 4.3 years). TOOMEY ET AL. HEALTH : PHYSIOLOGICAL AGEING PROCESS Most of the subjects were employed in light industry or office work. TESTING PROCEDURE-The Adult Growth Examination (AGE), (Morgan and Fevens, 1972), includes three basic subtests which have been reported by Morgan to be the most reliable and easily measured indicators of biological ageing. These are: systolic blood pressure, near point of vision, and auditory threshold at 6 kHz. Subjects were administered the AGE tests according to Morgan's protocol. The majority of subjects were tested on two separate days within a three-week period. Each session lasted approximately twenty minutes. Systolic blood pressure was measured with a random zero sphygmomanometer (Gelman Hawksley, England), the appearance of the first sound being taken as the systolic pressure. The value of systolic blood pressure used was the average of three readings taken at rest in the sitting position separated by the intervening activity of the other two tests. Near point of vision was taken as the closest distance for uncorrected binocular vision at which a sentence in 12 point characters could be read without blurring. The auditory threshold was measured at 6 kHz for the better ear after a rehearsal at 1 kHz (1702 recording audiometer, Grayson Stadler, U.S.A.). ANALYSIS-AGE scores were derived according to the methods described by Morgan. This involves using conversion tables taken from normative data (obtained from the U.S. National Health Survey) to convert the raw score from the average reading of each subtest to the equivalent age score. The three age scores were then ranked and the median taken to be the biological age. The difference between this median biological age score and the chronological age of the subjects was then compared with the years of participation in the Transcendental Meditation and TM-Sidhi programme in a correlation analysis. Because of its predictive ability and greater rigour, multiple regression analysis was also carried out on the data, each physiological variable being modelled separately using forward stepwise analysis. The objective of this statistical exploration of the data was to investigate further the relationship of each variable-systolic blood pressure, auditory threshold -PAPER 245 and near point of vision-with the number of years of practice of the Transcendental Meditation and TM-Sidhi programme, and the chronological age and sex of the subjects. Since years of practising the Transcendental Meditation technique and years of practising the TM-Sidhi programme were highly correlated, (r= .570, N= 173, p< .001), these two variables were combined to produce one variable (TMSD) in order to avoid problems of collinearity. This variable therefore represents the total time invested in the Transcendental Meditation and TM-Sidhi programme. It increases annually by one unit for someone practising only Transcendental Meditation and by two units for someone practising the Transcendental Meditation and TM-Sidhi programme. The other regressors fitted to the models were age (years), and sex (1 for men and 0 for ladies). In order to avoid potential problems from using normative data, another method of assessment of physiological age-functional age as defined by Webster and Logie (1976)-was calculated for each subject. This measure is derived from the sample rather than norms. A multiple regression model was constructed using the individual subtests and sex as dependent variables, age being the independent variable. Functional age was then calculated for each subject from this model. The difference between functional age and chronological age was then correlated with the years of participation in the Transcendental Meditation and TM-Sidhi programme (as the combined TMSD variable defined above). RESULTS The Adult Growth Examination scores showed that the subjects of this sample had a biological age that was on average 7.2 years younger than their average chronological age of 31.8 years, a highly significant difference (1=7.15, N= 173, p<.OOl). The results are summarized in table l. In addition, the length of time of participation in the Transcendental Meditation and TM-Sidhi programme was significantly correlated with the reduction in biological age (r= - .329, N = 173, p< .001). I Similarly, the difference between functional age and chronological age was significantly correlated with years of practice of the Transcendental Meditation and TM-Sidhi programme (r=- .351, N= 173, p< .001). 1873 SCIENTIFIC RESEARCH ON THE TRANSCENDENTAL MEDITATION AND TM-SIDHI PROGRAMME, VOL . 3 TABLE I DETAILS OF THE SAMPLE AND REsULTS OF THE ADULT GROWTH EXAMINATION LADIES MEN (N=l27) TOTAL (N= 173) (N = 46) Mean S.D. Mean S.D. Mean S.D. 30.7 8.0 35.0 11.2 31.8 9.1 Duration of the practice of Transcendental Meditation (years) 6.5 2.8 6.5 3.5 6.5 3.0 Duration of practice of the TM-Sidhi programme (years) 2.1 1.2 2.3 1.3 2.1 1.2 TMSD* (years) 8.5 3.7 8.7 4.4 8.6 3.9 11.9 Age (years) 122.3 11.2 113 .4 11.6 120.0 Near point of vision (inches) 4.0 1.5 6.2 5.7 4.6 3.3 Auditory threshold (dB) 6.4 12.1 8.9 13.5 7.1 12.5 22.9 7.4 29.6 12.6 24.7 9.5 -7.8 7.4 -5.4 8.7 -7.2 7.8 Systolic blood pressure (mmHg) Biological age (years) Difference between biological age and chronological age • TMSD =years of practice of Transcendental Meditation added to years of practice of the TM-Sidhi programme TABLE 2 SUMMARY OF MULTIPLE REGRESSION MODELS EQUATION I. MODEL OF SYSTOLIC BLOOD PRESSURE Systolic blood pressure (mmHg) = 101.9""" + (10.78••• x sex) + (0.49••• x age)+ [- 0.64••• x (TM years+ TM-Sidhi years)) R 2 =0.243***, F= 18 .1, N= 173 . EQUATION 2. MODEL OF NEAR POINT OF VISION Near point of vision (inches) = 0.937NS> + ( -1.583*" x sex)+ (0.151° 00 x age) vision. It should be pointed out that in general the near point of vision of these subjects was lower than the norms for their ages. 3. Ladies had consistently lower values of systolic blood pressure than men. Near point of vision was also different in men than in ladies but auditory threshold was not. Summary data for each of the multiple regression models is given in table 2. R 2 =0.2ll***,F=28.6, N= 173 . EQUATION 3. MODEL OF HEARING THRESHOLD AT 6kHz Hearing threshold level at 6kHz (dB)= -6.749*+(0.58•••xage) + [ - 0.541* x (TM years+ TM-Sidhi years)) R 2 =0.161**",F=i1 . 1, N=l73 . Sex is I for men and 0 for women. • p<O.OS •• p<O.Ol •••p<O.OOI A significant correlation between biological age and the age at which the subject learned the Transcendental Meditation technique was also found (r= .67, N= 173, p< .001). The multiple regression analysis revealed that: 1. Age was significantly predictive of higher systolic blood pressure, increased near point of vision, and increased auditory threshold. 2. Duration of practice of the Transcendental Meditation and TM-Sidhi programme was significantly predictive of lower systolic blood pressure and reduced auditory threshold, but was not significantly related to near point of 1874 DISCUSSION The results of the AGE analysis of the data are comparable to those of Wallace and his colleagues discussed above. Furthermore, the present findings extend those of Wallace et al. to a younger age group. Whereas the average age in Wallace's study was 53 years, the mean age of the male subjects in this study was 30.8 years, and that of the female subjects, 34.9 years. The results with regard to biological age are also supported by the correlation found between the difference of functional age from chronological age and years of practice of the Transcendental Meditation and TM-Sidhi programme. Thus the two different methods, norm-based and sample-based, agree that the degree to which physiological age is younger than chronological age increases in proportion to years of practice of the Transcendental Meditation and TM-Sidhi programme. TOOMEY ET AL. HEALTH : PHYSIOLOGICAL AGEING PROCESS The multiple regression models, looking at the structure of the cross-sectional data in more depth, show that duration of participation in the Transcendental Meditation and TM-Sidhi programme was significantly related to scores on two of the three measures of the Adult Growth Examination: systolic blood pressure and auditory threshold. The significant regression coefficients for Transcendental Meditation and TM-Sidhi programme participation with respect to these two age-related variables, indicate that the duration of participation is a significant predictor of improvement in these variables, independent of the other factors in this study (age and sex of the subjects). It was our hypothesis that the Transcendental Meditation and TM-Sidhi programme would have the effect of reversing physiological changes that occur with ageing. This was observed to occur with systolic blood pressure and auditory threshold at 6 kHz, but not with near point of vision. An effect of slowing or reversal of the deterioration of near point of vision might be revealed in older subjects in whom deterioration from the ideal situation would ordinarily be more advanced. This would be an interesting topic for further research. In this study we have derived linear multiple regression models for the data but there is no reason to suppose that the underlying relationships between physiology, age, and length of practice of the Transcendental Meditation and TM-Sidhi programme are linear. The progression of blood pressure, near point of vision, and auditory threshold at 6 kHz with age is certainly not constant throughout life (see for example Hofstetter, 1954; Hinchcliffe, 1959; Miall, and Lovell, 1967). It will be valuable to investigate in future studies whether the rate of reversal of ageing depends initially on the degree of ageing that has already taken place, and further to investigate the relationship between the rate of reversal of ageing and length of time practising Transcendental Meditation. Two alternative patterns would seem to be most probable: 1. The biological age may approach that of a healthy young adult in an asymptotic fashion, in which case, the rate of reversal of ageing would become less with time. 2. Improvements in physiological functioning may continue over and above the extent necessary to restore the biological age of early -PAPER 245 adulthood, to produce a state of higher physiological efficiency and integration. This second hypothesis is supported by many existing findings on the Transcendental Meditation and TM-Sidhi programme (for example Orme-Johnson, 1973; Pelletier, 1974; Blasdell, 1977; Clements and Milstein, 1977; Orme-Johnson and Granieri, 1977; Warshal, 1980; Daniels, in press; Wallace et al., in press). These factors will be examined in further longitudinal studies. A characteristic pattern of ageing, particularly in later years, is the occurrence of a vicious circle among a number of the factors that characterize the ageing process. For example, a decline in physical function would cause a decline in mental well-being, which in itself could lead to an accumulation of stress and tension precipitating a further worsening of physical condition. This compounding of effects is observed only too often by medical practitioners and social workers. The effectiveness of Transcendental Meditation in reversing the usual pattern of ageing can be seen from its effect in breaking this vicious circle of ageing by bringing about improvements in the major factors associated with the ageing process, both physiological and psychological. Previous research findings on the Transcendental Meditation and TM-Sidhi programme show directly a reversal of the deteriorative effects of ageing on a wide range of parameters. Furthermore, improvements have been seen in all the major factors predisposing longevity (Clements and Clements, 1980). The mechanisms for this comprehensive improvement have been investigated in terms of an holistic growth factor-the growth of higher states of consciousness-and studies have now been conducted (Haynes et al., 1977; Levine et al., 1977; Orme-J ohnson et al., 1977) relating the experience of higher states of consciousness resulting from the Transcendental Meditation and TM-Sidhi programme to high EEG coherence, a measure of cortical integration or communication. These two parameters have been further correlated with f"owth in a number of psychological variables, together with improvements in neurological efficiency (Haynes et al., 1977; Orme-Johnson and Haynes, 1981; Dillbeck et al., 1981). Therefore, the effectiveness of Transcendental 1875 SCIENTIFIC RESEARCH ON THE TRANSCENDENTAL MEDITATION AND TM-SIDHI PROGRAMME , VOL . 3 Meditation in reversing the ageing process may be incorporated into the following model: Transcendental Meditation produces a state of overall well-being and integration operationally defined in terms of the growth of a higher state of consciousness linked to the occurrence of a high degree of cortical integration (measured as high intra- and interhemispheric EEG coherence). In turn this high degree of integration in central nervous functioning gives rise to autonomic stability and greater physiological efficiency (OrmeJohnson, 1973; Appelle and Oswald, 1974; McDonagh and Egenes, 1977; Warshal, 1980) leading also to a more mature, balanced personality (Seeman et al., 1972; Ferguson and Gowan, 1976) and a better mental and physical health profile (Hjelle, 1974; Wilson et al., 1975; Blackwell et al., 1975; Cooper and Aygen, 1978 and 1979; Wallace et al., 1972a and in press). These different factors of integration and well-being contribute towards positive health habits (Wallace et al., 1972b; Shafri et al., 1975; Lazaret al., 1977; Monahan, 1977) and a general style of living which, in itself, is conducive to maintenance of good health and to the prevention of the ageing process, reinforcing the benefits that occur at a more fundamental physiological level. Studies from many different angles contribute to our understanding of this chain of improvements. Further work is now under way to extend this study to a broader range of important mental, physical, and social factors, as well as to examine larger numbers of subjects practising the Transcendental Meditation and TM-Sidhi programme from a wide age range. Finally, it is hoped to use the results of these studies as the basis for widespread and systematic application of Transcendental Meditation to ameliorate many of the problems of ageing now experienced in our society. ACKNOWLEDGEMENTS 'The authors would like to acknowledge the very able assistance of Carol George and the co-operation of the management and staff of the AEC factory at Skelmersdale, Lancashire. REFERENCES APPELLE, S., and OSWALD, B. A. 1974. Simple reaction time as a function of alertness and prior mental activity. 1876 Perceptual and Motor Skills 38: 1263- 1268. (Also in Scientific research on the Transcendental Meditation program: Collected papers, vol. 1, ed. D. W. Orme-Johnson and J. T. Farrow, pp. 312-315. 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