List of Tables
Himika, 2011
LIST OF TABLES
Page Numbers
01.
Constituents of betel quid
8
02.
Ranges in concentration of the chemical constituents of a variety
unprocessed green and ripe areca nuts
11
03.
Alkaloid content of fresh areca nuts from Darwin, Australia
11
04.
Mutagenicity of Arecoline in Salmonella typhimurium TA 100 and TA 98
(with or without S9)
19
05.
Mutagenicity of Arecoline N-Oxide in Salmonella typhimurium TA 100
and TA 98
21
06.
Table showing areca nut alkaloid Arecoline and Mitomycin C dose,
route of administration and exposure period
52
07.
Table showing metabolites of Arecoline, Arecaidine, Arecoline N-oxide
and N methyl Nipecotic acid dose, route of administration and
exposure period
54
08.
Table showing areca nut extract, sadagura extract and areca nut with
sadagura extract dose, route of administration and exposure period
56
09.
Table showing areca nut extract, sadagura extract and areca nut with
sadagura extract, Dalton's lymphoma ascites treatment mode and
exposure period
74
10.
Frequency of chromosomal aberrations in the bone marrow cells of
mice induced by areca nut alkaloid arecoline at 24 hour of treatment
85
11.
Frequency of chromosomal aberrations in the bone marrow cells of
mice induced by areca nut alkaloid arecoline at 48 hour of treatment
86
12.
Frequency of micronucleus in the bone marrow cells of mice induced by
areca nut alkaloid arecoline at 24 and 48 hours of exposure period
88
13.
Incidence of sperm head abnormality (SHA) induced by areca nut
alkaloid arecoline and total sperm count in mice
90
14.
Frequency of chromosomal aberrations in the bone marrow cells of
mice induced by metabolite of arecoline i.e., arecaidine at 24 hour of
treatment
94
15.
Frequency of chromosomal aberrations in the bone marrow cells of
mice induced by metabolite of arecoline i.e., arecaidine at 48 hour of
treatment
95
16.
Frequency of micronucleus in the bone marrow cells of mice induced by
arecaidine at 24 and 48 hours of exposure period
96
iv
List of Tables
Himika, 2011
17.
Incidence of spenn head abnormality induced by arecaidine and total
sperm count in mice
99
18.
Frequency of chromosomal aberrations in the bone marrow cells of
mice induced by arecoline N-oxide at 24 hour of treatment
102
19.
Frequency of chromosomal aberrations in the bone marrow cells of
mice induced by arecoline N-oxide at 48 hour of treatment
103
20.
Frequency of micronucleus in the bone marrow cells of mice induced by
arecoline N-oxide at 24 and 48 hours of exposure period
105
21.
Incidence of sperm head abnormality induced by arecoline N-oxide and
total sperm count in mice
107
22.
Frequency of chromosomal aberrations in the bone marrow cells of mice
induced by N-methyl nipecotic acid at 24 hour of treatment
110
23.
Frequency of chromosomal aberrations in the bone marrow cells of
mice induced by N-methyl nipecotic acid at 48 hour of treatment
111
24.
Frequency of micronucleus in the bone marrow cells of mice induced by
N-methyl nipecotic acid at 24 and 48 hours of exposure period
113
25.
Incidence of sperm head abnormality induced by N-methyl nipecotic
acid and total sperm count in mice
116
26.
Frequency of chromosomal aberrations in the bone marrow cells of
mice induced by areca nut extract at 24 hour of treatment
124
27.
Frequency of chromosomal aberrations in the bone marrow cells of
mice induced by areca nut extract at 48 hour of treatment
125
28.
Frequency of micronucleus in the bone marrow cells of mice induced
by areca nut extract at 24 and 48 hours of exposure period
127
29.
Incidence of sperm head abnormality induced by areca nut extract and
total sperm count in mice
130
30.
Frequency of chromosomal aberrations in the bone marrow cells of
mice induced by sadagura extract at 24 hour of treatment
134
31.
Frequency of chromosomal aberrations in the bone marrow cells of
mice induced by sadagura extract at 48 hour of treatment
135
32.
Frequency of micronucleus in the bone marrow cells of mice induced
by sadagura extract at 24 and 48 hours of exposure period
137
33.
Incidence of sperm head abnormality induced by sadagura extract and
total sperm count in mice
139
34.
Frequency of chromosomal aberrations in the bone marrow cells of
mice induced by areca nut with sadagura extract at 24 hour of
treatment
143
List of Tables
Himika, 2011
35.
Frequency of chromosomal aberrations in the bone marrow cells of
mice induced by areca nut with sadagura extract at 48 hour of
treatment
144
36.
Frequency of micronucleus in the bone marrow cells of mice induced
by areca nut with sadagura extract at 24 and 48 hours of exposure
period
146
37.
Incidence of sperm head abnormality induced by areca nut with
sadagura extract and total sperm count in mice
148
38.
Table showing difference in Arecoline induced lipid peroxidation given
by intraperitoneal and oral route for 24 hour, 48 hour and 72 hour of
exposure time
157
39.
Table showing comparison of Arecoline induced lipid peroxidation
given by intraperitoneal and oral route for 24 hour exposure time and
intervention studies by antioxidant Vitamin C
158
40.
Table showing Arecaidine induced lipid peroxidation after 24 hour
exposure time and intervention studies by antioxidant Vitamin C
161
41.
Table showing Arecoline N-oxide induced lipid peroxidation after 24
hour exposure time and intervention studies by antioxidant Vitamin C
163
42.
Table showing Nipecotic acid induced lipid peroxidation after 24 hour
exposure time and intervention studies by antioxidant Vitamin C
164
43.
Table showing Areca nut extract induced lipid peroxidation after 24
hour exposure time and intervention studies by antioxidant Vitamin C
165
44.
Table showing Sadagura extract induced lipid peroxidation after 24
hour exposure time and intervention studies by antioxidant Vitamin C
170
45.
Table showing Areca nut with sadagura extract induced lipid
peroxidation after 24 hour exposure time and intervention studies by
antioxidant Vitamin C
172
46.
Table showing the effect of areca nut and sadagura extracts treated
alone or in combination on the Mean Survival Time of with or without
Dalton's Lymphoma bearing mice
175
47.
Table showing the effect of areca nut and sadagura extracts alone or in
combination on the body weight of with or without DLA bearing mice
178
48.
Table showing the effect of areca nut and sadagura extracts alone or in
combination on the tumor volume in terms of Packed Cell Volume of
Dalton's Lymphoma Ascites (DLA) bearing mice
179
VI