How the Ocean
Heals Lyme Disease:
What the Evidence Shows
Kristen T. Honey, PhD
[email protected]
Integrative Lyme Solutions
Academy of Comprehensive Integrative Medicine
June 22, 2013, Dallas, TX
How the Ocean
Heals Lyme Disease
www.HoneyHoneyHealing.org
Talk Outline
Share & encourage dialogue for solutions available NOW:
(1) My healing journey:
100% Lyme recovery possible with
holistic approach, tenacity, resilience.
Talk Outline
Share & encourage dialogue for solutions available NOW:
(1) My healing journey:
100% Lyme recovery possible with
holistic approach, tenacity, resilience.
(2) Oligotherapy:
Healing power of trace minerals for therapeutic support,
especially bioavailable minerals from ocean.
Talk Outline
Share & encourage dialogue for solutions available NOW
(1) My healing journey:
100% Lyme recovery possible with
holistic approach, tenacity, resilience.
(2) Oligotherapy:
Healing power of trace minerals for therapeutic support,
especially bioavailable minerals from ocean.
(3) Nano-mineral treatments:
Emerging science & technology for new frontiers of
treatments with nano-silver and nano-gold to eradicate
Lyme-related infections and symptoms.
Talk Outline
Share & encourage dialogue for solutions available NOW:
(1) My healing journey:
100% Lyme recovery possible with
holistic approach, tenacity, resilience.
(2) Oligotherapy:
Healing power of trace minerals for therapeutic support,
especially bioavailable minerals from ocean.
(3) Nano-mineral treatments:
Emerging science & technology for new frontiers of
treatments with nano-silver and nano-gold to eradicate
Lyme-related infections and symptoms.
(4) Curing Lyme:
YES we can! (with patient self-care & partnership)
Talk Outline
Share & encourage dialogue for solutions available NOW:
(1) My healing journey:
100% Lyme recovery possible with
holistic approach, tenacity, resilience.
(2) Oligotherapy:
Healing power of trace minerals for therapeutic support,
especially bioavailable minerals from ocean.
(3) Nano-mineral treatments:
Emerging science & technology for new frontiers of
treatments with nano-silver and nano-gold to eradicate
Lyme-related infections and symptoms.
(4) The Lyme Cure:
YES we can! (with patient self-care & partnership)
Problem solving for recovery
through a lens of ecology & integrative systems thinking
=> fresh perspective on Lyme disease
Together for Lyme Solutions
Part 1: My Story
Share & encourage dialogue for solutions available NOW:
My Healing Journey
From Stanford PhD… to food stamps… and back!
•
•
•
1999 tick bites
Decade of mystery symptoms & increasing illness
2009 collapse with late-stage, neurological Lyme disease
My Healing Journey
From Stanford PhD… to food stamps… and back!
•
•
•
Healing is a full-time job
Lifestyle overhaul, which not all patients will do (diet, EMFs, etc.)
Integrated approach with emotional grief of loss & surrender
My Healing Journey
From Stanford PhD… to food stamps… and back!
•
•
•
Healing is a full-time job
Lifestyle overhaul, which not all patients will do (diet, EMFs, etc.)
Integrated approach with emotional grief of loss & surrender
INVISIBLE
ILLNESS:
Lyme patients
can be very
skilled at hiding
symptoms by
showing
themselves only
on “good” days...
…until there are
not enough
hours in a day to
“fake it”
Volatile
symptoms
Volatile
disease
My Healing Journey
What can one patient, or one practitioner, do?
Be the change!
YOU are the leader
you’ve been waiting for!
Steve Schneider
My Healing Journey
10 years, six months & many doctors later…
Patient #1 goal: SURVIVE
Navigate way to a
medical champion, LLMD, &
integrative team for healing
support on ALL levels
Dr. Klinghardt’s 5 levels of healing
My Healing Journey
10 years, six months & many doctors later…
Mind-body-spirit work for
comprehensive, holistic healing
Dr. Klinghardt’s 5 levels of healing
My Healing Journey
Modified Dr. Klinghardt’s 5 levels of healing
to reflect “biggest bang for the buck”
World
flipped
upside
down
My Healing Journey
Rest. Breathe. Sleep. Pray.
Accept. Surrender.
Heal
My Healing Journey
Modified Dr. Klinghardt’s 5 levels of healing
plus CONTEXT MATTERS, a la Bruce Lipton
My Healing Journey
Shoulders of Giants to create my LLMD Team
Systems Approach
on the
Shoulders of Giants:
The human body is its own
ecosystem—much like the
ocean—with resilience,
hysteresis, synergistic
properties, and multi-system
dynamics that depend on
matrix conditions.
GRATITUDE
My Lynchpin
Nanosilver & Nanogold
Oligotherapy, experimental nanosilver & nanogold
GRATITUDE
Together for Lyme Solutions
Part 2: Oligotherapy
Share & encourage dialogue for solutions available NOW:
Oligotherapy
Using minerals & trace elements as catalysts to
maintain physiological functions and restore the
body’s natural vitality
•
Healthy diet is the essential foundation of overall good health
•
Today’s soil quality & food depleted of essential minerals
•
Modern pollution & chronic stresses compound problem
•
Mineral supplementation, in proper form, catalyzes healing
Oligotherapy
Minerals and Trace Elements
•
Human body: 60%-70% solution of minerals & trace elements
•
Our hydro-mineral composition & relative proportions are key
•
In 3 billion years Nature found a way to utilize ALL the elements
•
Ocean water a natural source of ALL mineral forms:
Nano or Ionic, Colloidal, Chelated, Carbon-Organo-Complexes
Oligotherapy & Matrix Matters
Broader context from an evolutionary biology,
systems perspective
3+ Billion Years of Evolution in the Primordial Ocean
Life’s Architect: Seawater
Broader context from an evolutionary biology,
systems perspective
3+ Billion Years of Evolution in the Primordial Ocean
PRIMORDIAL OCEAN
Animal Species Emerge from the Ocean
Begin Landmass Formation
Cellular Life Begins
“Water” Covers Earth
Ocean Healing
Broader context from an evolutionary biology,
systems perspective
“The only way
cellular life could
leave the ocean
was to take the
ocean with it.”
- RENÉ QUINTON
“The French Darwin”
Revolutionary
Biologist
Ocean Healing
“The Terrain is Everything”
- Claude Bernard (1850)
Still true today because
the Primordial Ocean became our internal terrain
60-70% of us
are functional
fluids evolved
from seawater
Ocean Healing
“The Matrix Matters!”
as we say in ecology; in medicine, it has other names:
…
• Internal Matrix
• Liquid Matrix
• Internal Terrain
• Biological Terrain
• Internal Ocean
• Milieu Interieur
• Internal Environment
“The internal environment is then the primordial
physiological basis of the organism, its‘liquid matrix’.”
- Dr. Walter Cannon (Harvard, author of The Wisdom of the Body)
Ocean Healing
Pragmatic solution: Original Quinton
Composition of Quinton marine
plasma near identical to human
“biological terrain”
•
Quinton Isotonic
•
Extra-cellular fluid
•
Blood plasma
“The tides are in our veins” - Robinson Jeffers
Disclosure: I have no financial stake in the Original Quinton company or
products but recently began collaborating with their staff for on-going
research with support for my participation in the 2013 Santa Fe Institute
Complex Systems program: http://www.santafe.edu
Ocean Healing
Pragmatic solution: Original Quinton
•
Seawater – Complex solution of the
Periodic Table and “marine factors”.
•
“Amniotic Fluid” of cellular life
•
Pischinger: “We now carry the Primordial
Sea around within us.”
•
In Stone: “Terrain is Everything”
•
Isotonic the medicine – Hypertonic the
nutrient
•
All mineral forms: Ionic, colloidal, chelated,
carbon-organo-complexed
•
Re-establish elements in the milieu interieur
to marine “inheritance”
The ocean is a global system essential to all life, including yours!
Ocean Healing
Health is like the ocean in more ways than one:
Ocean Dead Zone ~ Human Detox Pathways
Ocean Healing
Health is like the ocean in more ways than one:
Ocean Dead Zone ~ Human Detox Pathways
It’s all about CIRCULATION -• CIRCULATION of water
• CIRCULATION of blood
Ocean Healing
My ocean health analogy = Dr. Cowden’s bathtub
To support the
Matrix, it’s all
about rates of
change… Think
healing PROCESS!
Together for Lyme Solutions
Part 3: Nano-Mineral Treatments
Share & encourage dialogue for solutions available NOW:
Nano-Mineral Treatments
Emerging technologies for new treatment frontiers
Nanoparticles: particles <100nm diameter with new or
enhanced size-dependent properties, compared with
larger particles of the same material.
NOT talking man-made chemicals or futuristic bio-nanorobots
Nano-Mineral Treatments
Emerging technologies for new treatment frontiers
Nano-minerals 101:
• Nano-structures exist naturally in nature, yet we only
recently developed technology to detect
• Ionic minerals are naturally nano-minerals
• Nanotechnology modifies the surface-area-tovolume ratios of particles
• Smaller sizes, greater reactivity
• Trade-off between reactivity & instability
• Greater reactivity, higher potential energies
Nano-Mineral Treatments
Emerging technologies for new treatment frontiers
Nano-minerals 101:
• Nano-structures exist naturally in nature, yet we only
recently developed technology to detect
• Ionic minerals are naturally nano-minerals
• Nanotechnology modifies the surface-area-tovolume ratios of particles
• Smaller sizes, greater reactivity
• Trade-off between reactivity & instability
• Greater reactivity, higher potential energies
New potential when silver goes nano…
Medical History of Silver
•
Silver used topically & internally for 6,000+ years
•
Scientifically noted to purify water by 1869
•
Colloidal silver used medicinally since 1860s, when coined term to
describe silver suspended in a “stable, indeterminate state of matter”
Just published this week:
NanoSilver Potential
Nanosilver kills bacteria and lower-level
organisms (not mammalian cells) by wreaking
havoc in the structure of membrane surfaces.
•
One nanoparticle binds to multiple Borrelia Burgdorferi (Bb) cells, the
spirochetal, Gram negative bacteria causing Lyme (Ou et al. 2005).
Qu L. et al., Visulaizing andhesion-induced agglutination of Escherichia coli with mannosyulated
nanoparticles, J. Nanosci Nanotechnol. 2005 Feb; 5(2):319-22.
•
Colloidal silver acts as a powerful catalyst with ability to attack one-celled
organisms (i.e. bacteria, viruses, & fungi) by simultaneous ion and
catalectic mechanisms (Ghazvini et al.), blocking respiration and causing
the organism to suffocate and die.
Ghazvini, K., MirzaHesabi, E., Akbarein, M. M., & Crémieux, A. (2008). Antibacterial activity of a
malodor neutralizer containing silver nanoparticles. Navid No Journal, 42, 56-60.
NanoSilver Potential
(continued)
•
“Silver kills bacteria by strangling them in a warm & moist environment.
Highly bioactive silver ions bind with proteins inside & outside bacterial cell
membranes, thus inhibiting respiration & reproduction” (Wasif &Laga 2009)
Wasif, A. I., & Laga, S. K. (2009). Use of nano silver as an antimicrobial agent for cotton. AUTEX
Res. J, 9(5), 13.
•
Nanosilver particles attack particular microbes, using species-specific
mechanisms (Song et al. 2006, Ruparelia 2008).
Song, H. Y., Ko, K. K., Oh, I. H., & Lee, B. T. (2006). Fabrication of silver nanoparticles and their
antimicrobial mechanisms. Eur Cells Mater, 11(Suppl 1), 58.
Ruparelia, J. P., Chatterjee, A. K., Duttagupta, S. P., & Mukherji, S. (2008). Strain specificity in
antimicrobial activity of silver and copper nanoparticles. Acta Biomaterialia, 4(3), 707-716.
•
Nanosilver prevents biofilm formation (Gibbins and Warner 2005).
Gibbins, B., & Warner, L. (2005). The role of antimicrobial silver nanotechnology. Medical Device
& Diagnostic Industry Magazine, 1, 1-2.
NanoSilver Potential
(continued)
Antimicrobial mechanisms of nanosilver include:
•
Inhibition of cell wall synthesis, protein synthesis, & nucleic acid synthesis
(Lara et al., 2010).
Lara, H. H., Ayala-Núnez, N. V., Turrent, L. D. C. I., & Padilla, C. R. (2010). Bactericidal effect of
silver nanoparticles against multidrug-resistant bacteria. World Journal of Microbiology and
Biotechnology, 26(4), 615-621.
•
Cell-wall “pitting” (Choi et al., 2008).
Choi, O et al. (2008). The inhibitory effect of silver nanoparticles, silver ions and silver chloride
colloids on microbial growth, in Water Red, 42(12): 3066-74.
•
Accumulation of silver nanoparticles in bacterial membrane (Elechiguerra
et al. 2005).
Elechiguerra, J. L., Burt, J. L., Morones, J. R., Camacho-Bragado, A., Gao, X., Lara, H. H., &
Yacaman, M. J. (2005). Interaction of silver nanoparticles with HIV-1. J nanobiotechnol, 3(6), 1-10.
•
On-going investigation required to fully understand mechanisms
(Marambio-Jones & Hoek 2010).
Marambio-Jones, C., & Hoek, E. M. (2010). A review of the antibacterial effects of silver
nanomaterials and potential implications for human health and the environment. Journal of
Nanoparticle Research, 12(5), 1531-1551.
NanoSilver Potential
(continued)
Antimicrobial properties already in medical applications including:
•
Topical silver widely used in wound & burn treatment to prevent scarring &
enhance healing. (Gibbins & Warner 2005).
Gibbins, B., & Warner, L. (2005). The role of antimicrobial silver nanotechnology. Medical Device
& Diagnostic Industry Magazine, 1, 1-2.
•
Silver-containing dressings to combat MRSA (Thomas 2004).
Thomas, S. (2004). MRSA and the use of silver dressings: overcoming bacterial resistance.
World Wide Wounds.
•
Widely used in silver-based dressings & silver coated medicinal devices
(e.g., nanogels, nanolotions, & catheters) (Rai 2009, Baratchi et al. 2009,
Estevez & Erlichman 2011).
Rai, M., Yadav, A., & Gade, A. (2009). Silver nanoparticles as a new generation of antimicrobials.
Biotechnology advances, 27(1), 76-83.
Baratchi, S., Kanwar, R. K., Khoshmanesh, K., Vasu, P., Ashok, C., Hittu, M., ... & Kanwar, J. R.
(2009). Promises of nanotechnology for drug delivery to brain in neurodegenerative diseases.
Current Nanoscience, 5(1), 15-25.
Estevez, A. Y., & Erlichman, J. S. (2011). Cerium Oxide Nanoparticles for the Treatment of
Neurological Oxidative Stress Diseases. brain, 28, 30.
NanoSilver Potential
Application for Lyme & Tick-Borne Coinfections
Few clinical studies, if any, evaluate the efficacy of
nanosilver to treat Lyme (or tick borne diseases)
Anecdotal case studies, like me, and peer-reviewed
studies on general antimicrobial efficacy suggest that
nanosilver can successfully treat Lyme infections—
both alone and in combination with antibiotics:
• low risk
• high effectiveness by “smothering” bacteria
• synergistic effects improve antibiotic efficacy
• microbes’ inability to evolve a silver-resistant form
NanoSilver Potential
Improved Antibiotic Efficacy
Laboratory studies demonstrate a synergistic
antibacterial effect between nanosilver & antibiotics
(Shahverdi 2007):
• penicillin G
• amoxicillin
• erythromycin
• clindamycin
Shahverdi, A. •
R., Fakhimi,
A., Shahverdi, H. R., & Minaian, S. (2007). Synthesis and effect of
vancomycin
silver nanoparticles on the antibacterial activity of different antibiotics against Staphylococcus
aureus and Escherichia coli. Nanomedicine: Nanotechnology, Biology and Medicine, 3(2), 168171.
• May aid antibiotic transport across blood-brain barrier
• Penetrates biofilms for increased antibiotic efficacy
Morones-Ramirez, J.R., J.A. Winkler, C.S. Spina, J.J. Collins. 2013. Silver enhances
antibiotic activity against gram-negative bacteria. Science Translational Medicine.
5(190):190ra81, DOI: 10.1126/scitranslmed.3006276
Medical History of Gold
• Gold used topically & internally for 5,000+ years
• Gold in dentistry ~4,500 years ago
• Anti-inflammatory, used to treat sore joints in 1900s,
as well as arthritis in 20th Century
NanoGold Potential
Extremely good catalyst, acts as a semiconductor
Potential applications:
• Rapid diagnosis technologies, including diagnosis of Lyme
disease, rickettsioses, ehrlichioses, and anaplasmosis.
• Cancer treatments without surgery, “nanobullets” that travel inside
cancer cells and bind to internal structures to prevent cell division.
• Telomeres extension for increased longevity & anti-aging
• Synergisms with nanosilver for increased antimicrobial properties
• Synergisms with nanosilver to mitigate Lyme symptoms &
inflammation responses, possibly mitigate Herxheimer reactions
NanoGold Potential
Extremely good catalyst, acts as a semiconductor
Potential applications:
• Rapid diagnosis technologies, including diagnosis of Lyme
disease, rickettsioses, ehrlichioses, and anaplasmosis.
• Cancer treatments without surgery, “nanobullets” that travel inside
cancer cells and bind to internal structures to prevent cell division.
• Telomeres extension for increased longevity & anti-aging
• Synergisms with nanosilver for increased antimicrobial properties
• Synergisms with nanosilver to mitigate Lyme symptoms &
inflammation responses, possibly mitigate Herxheimer reactions
New potential when gold goes nano…
Together for Lyme Solutions
Part 4: The Lyme Cure
Share & encourage dialogue for solutions available NOW:
The Lyme Cure
YES
we
can!
No magic bullet, yet people CAN heal if they believe
recovery possible – I am proof.
100% recovery is an ACTIVE PROCESS with commitment on ALL levels
YES We Can! Here’s How:
Share & encourage dialogue for solutions available NOW:
(1) Late-stage Lyme disease exists and is challenging
to treat, yet 100% recovery must be our goal.
•
There are many paths to Rome
•
Active patient involvement is a MUST
www.HoneyHoneyHealing.org
YES We Can! Here’s How:
Share & encourage dialogue for solutions available NOW:
(1) Late-stage Lyme disease exists and is challenging
to treat, yet 100% recovery must be our goal.
•
There are many paths to Rome
•
Active patient involvement is a MUST
(2) Trace minerals provide therapeutic support,
especially bioavailable minerals from ocean.
www.HoneyHoneyHealing.org
YES We Can! Here’s How:
Share & encourage dialogue for solutions available NOW:
(1) Late-stage Lyme disease exists and is challenging
to treat, yet 100% recovery must be our goal.
•
There are many paths to Rome
•
Active patient involvement is a MUST
(2) Trace minerals provide therapeutic support,
especially bioavailable minerals from ocean.
(3) Nano-technology emerging science & new
frontiers of treatments healed me 100% & show
promise.
Lyme, coinfections, viruses
• Silver & nanosilver
•
}
Gold & nanogold
www.HoneyHoneyHealing.org
YES We Can! Here’s How:
Share & encourage dialogue for solutions available NOW:
(1) Late-stage Lyme disease exists and is challenging
to treat, yet 100% recovery must be our goal.
•
There are many paths to Rome
•
Active patient involvement is a MUST
(2) Trace minerals provide therapeutic support,
especially bioavailable minerals from ocean.
(3) Nano-technology emerging science & new
frontiers of treatments healed me 100% & show
promise.
Lyme, coinfections, viruses
• Silver & nanosilver
}
•
Gold & nanogold
(4) BELIEVE! We WILL recover 100% and cure Lyme.
•
100% recovery = functional cure
www.HoneyHoneyHealing.org
The Lyme Cure
YES
we
can!
Our medical paradigm & patients must overcome
“4 min mile” barrier to full Lyme recovery
www.HoneyHoneyHealing.org
The Lyme Cure
YES we can!
“We can’t solve problems by using the same kind
of thinking we used when we created them”
- Albert Einstein
Shoot for the moon and
land among the stars
www.HoneyHoneyHealing.org
The Lyme Cure
YES we can!
“We can’t solve problems by using the same kind
of thinking we used when we created them”
- Albert Einstein
Problem solving for recovery
through a lens of ecology & integrative systems thinking =>
fresh perspective on Lyme disease
www.HoneyHoneyHealing.org
The Lyme Cure
YES we can!
“We can’t solve problems by using the same kind
of thinking we used when we created them”
- Albert Einstein
People before profits –
a vision for open-source medicine
•
Share information
•
Encourage innovation
•
Technology-based solutions
•
Disruptive technologies with systems thinking for
paradigm shift to a better tomorrow
www.HoneyHoneyHealing.org
The Lyme Cure
YES we can!
“We can’t solve problems by using the same kind
of thinking we used when we created them”
- Albert Einstein
Infinite possibilities
through innovation…
www.HoneyHoneyHealing.org
How the Ocean
Heals Lyme Disease
“Whether you think you can,
or you think you can’t—
you’re right”
~ Henry Ford
www.HoneyHoneyHealing.org
Gratitude!
for support from
Problem solving is a team effort
& I’ve had a great team.
Stanford University
(Stanford Medical School still needs Lyme education)
•
•
•
•
•
E-IPER Department
Woods Institute for the Environment
Hopkins Marine Station, Biology Department
Terry Root & Steve Schneider, “The Patient from Hell”
Don Kennedy, Alfred Spormann, Cheryl Koopman
Thank you!
Questions
Welcome!
Santa Fe Institute
•
•
2013 Complex Systems Summer School
Matrix Matters! - Vishwa Reddy, Carol Strohecker,
Kerstin Damerau, Jody Wright, Tom Carter
Medical Support
•
•
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California LLMDs & Pacific Frontier Medical, CA
Dr. Klinghardt & Klinghardt Academy
Theocentric Holistic Healing & Counseling, WPB, FL
True North, Falmouth, ME
Columbia University Lyme & Tick-Borne Diseases, NY
Visionary Friends
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•
•
Lee Cowden, Bill Gonseaux, & Lisa Wade, ACIM
Wayne Harris, Advanced BioNutritional Research
Rob Slovak, Original Quinton
HoneyHoneyHealing.org
Hook, Line and Thinker by Ray Troll