PREVENTIVE MEDICINE 17, 135-154 (1988) Affective and Social Influences Approaches to the Prevention of Multiple Substance Abuse among Seventh Grade Students: Results from Project SMART WILLIAM B. HANSEN, PH.D.,* C. ANDERSON JOHNSON, PH.D.,*,~ BRIAN R. FLAY, D.PHIL., JOHN W. GRAHAM, PH.D., AND JUDITH SOBEL, PH.D. Division of Health Behavior Research, Department of Preventive Health Promotion and Disease Prevention Research, University Pasadena, California 91101 Medicine, and *Institute of Southern California, for TWO drug abuse prevention curricula were tested to determine their efftcacy in preventing the onset of tobacco, alcohol, and marijuana use among adolescents. The first program focused on prevention through social pressure resistance training. The second featured affective education approaches to prevention. Curricula were tested on seventh grade students. Subjects were pretested just prior to the program and were post-tested at 12 and 24. months. Post-test analyses indicated that the social program delivered to seventh grade subjects was effective in delaying the onset of tobacco, alcohol, and marijuana use. No preventive effect of the affective education program was observed. By the final post-test, classrooms that had received the affective program had significantly more drug use than controls. B 1988 Academic Press, Inc. INTRODUCTION Drug abuse, including cigarette and alcohol abuse, remains the major public health problem in this country today. Between 450,000 and 600,000 premature deaths are attributed to cigarettes, alcohol, and other drug abuse each year, nearly one-third of all mortality in the United States (42-44). Although cigarette smoking has declined from 43% among American adults in 1966 to the present rate of 32%, the proportion of heavy smokers (~25 cigarettes per day) has increased from 26 to 37% among males, and 13 to 25% among females. Alcohol is widely understood to have great addictive potential. Among various drugs, tobacco and alcohol rank first and second in public health significance, with the order depending upon where in the lifespan one concentrates. Most deaths in youth are the result of accidents and/or acts of violence (42) typically involving alcohol. Premature mortality and morbidity in mid-life are most often the result of chronic disease, to which cigarette smoking is the greatest contributor. Marijuana abuse is also a factor in accidents and acute respiratory disease. Marijuana’s contribution to cancer and chronic respiratory disease is unknown but there is reason to believe that long-term, heavy marijuana smoking may be a serious lung cancer risk factor. In addition to their contributions to chronic disease, tobacco, alcohol, and ’ Supported by Grant l-R18-DA030496 from the National Institute on Drug Abuse. 2 To whom reprint requests should be addressed, at U.S.C., Institute for Health Promotion and Disease Prevention Research, 35 North Lake Avenue, Suite 200, Pasadena, CA 91101. 135 0091-7435/88 $3.00 Copyright 0 1988 by Academic Press, Inc. AlI rights of reproduction in any form reserved. 136 HANSEN ET AL. marijuana are considered “gateway” drugs to other drug abuse because the likelihood of any substance abuse is greatly enhanced by the use of any of these three (27). The use of other substances such as cocaine, amphetamines, barbiturates, and opiates is extremely low for persons who have never experimented with any one of the three drugs. Drug abuse also presents a serious obstacle to the intellectual and social development of young people. In a 1982 national probability survey of high school seniors, the proportions reporting use of various substances over the previous 30 days were as follows: cigarettes, 30.0%; alcohol, 69.7%; marijuana/hashish, 28.5%; cocaine, 5.0%; stimulants, 10.7%; hallucinogens, 4.3%; and sedatives 3.4%. Reported daily use was 21.1% for cigarettes, 5.7% for alcohol, and 6.3% for marijuana (26). With the exception of cocaine, and perhaps tobacco, there has been a slight decline in the numbers of high school seniors reporting drug use in recent years. Of great concern, however, is the trend toward early onset. Risk for cancer, heart disease, and violent death increase with longer exposure to drugs. A trend toward earlier and longer lifetime exposure to drugs would suggest that unless effective, large scale, prevention programs are implemented, drug abuse will take an increasing toll in chronic disease, accidents, and acts of violence in years to come. The value of drug abuse prevention has been understood for some time (8). While notable progress is being made in effectively treating established substance abuse behaviors (1, 28), even the best treatments are still not widely effective in treating many substance abuse disorders (23). It may not be reasonable ever to expect treatment programs to have a major impact on the health and social costs associated with substance use. Preventing the initial onset of regular substance use appears to be the most cost-effective approach to prevention of drug abuse and its sequelae. SOCIAL INFLUENCES APPROACHES TO PREVENTION With the recent development of effective social skills and resistance training approaches for preventing (or at least delaying) the onset of cigarette smoking, the possibility of preventing other substance use is enhanced. Based on social psychological theories and research, this research has led to remarkable success in reducing the rates of onset of regular tobacco use (2, 4-6, 10, 12, 19, 22, 30-33, 38). The evaluations of these projects have been of improved quality over time, although it is clear that no study has perfect validity (11). Taken together, the weight of the evidence supports an effective technology for smoking prevention (3, 11). These programs have enjoyed relative successat achieving the goals of delaying onset and have been repeated in numerous settings (41). Different programs feature alterations on the specific techniques used, but most of the programs have featured one or more of the following components. Peer Pressure Resistance Training Students are instructed about the nature of peer pressure and are taught how to resist pressures to use cigarettes. The format and content of training has varied greatly but typically has included descriptions and demonstrations of resistance techniques accompanied with some method of practicing these techniques. PROJECT Correction of Normative 137 SMART Expectations Young people perceive tobacco use to be more prevalent and more acceptable than it really is (39, 40). Prevention programs provide students with information about true prevalence rates. Inoculation against Mass Media Messages Some psychosocial prevention programs provide students with about the advertising strategies used to promote tobacco and teach ysis skills to counter the influence that advertisements may have. extent, programs have also focused on countering the pro-tobacco portrayed in popular music, movies, and television programming. Information about Parental information critical analTo a lesser use images and Other Adult Influences Noting the correlation between parental cigarette smoking and student smoking, many programs include some information about parental influences. The message that parents need not be modeled is usually presented. Peer Leadership Most, but not all, of the programs referenced above include peer opinion leaders in the delivery of the program. The selection and training of peer leaders varies greatly from program to program. Nonetheless, data generally support the efficacy of using students in the delivery of all or some of the program. At least two studies have found peer leadership to contribute significantly to the robustness of program effects (4, 19). Other Components Many smoking prevention programs have included various other components that, although not strictly within the domain of the social influences model of smoking onset, nonetheless fit within the framework. Many programs feature information about the short-term and social consequences of smoking, e.g., the ingestion of carbon monoxide, bad breath, etc. This type of information was stressed since it was suspected that it would be more salient and harder to deny than long-term, severe consequences would be (16). In some programs (4, 12), instruction on decision-making was included. Making personal commitments not to smoke, either via contract or reading a commitment that is videotaped, is also included in many programs. This has been done to bolster nonsmoking attitudes using strategies well known to attitude researchers (18, 20). The independent effects of these additional components have not been established, however. COPING SKILLS AND AFFECTIVE EDUCATION ABUSE PREVENTION APPROACHES TO DRUG During the same time period that the social influences approach was being developed to prevent smoking, drug abuse prevention education, including programs for preventing alcohol abuse, were being developed that adopted a different 138 HANSEN ET AL. strategy for intervention. The content of many of these programs focused on potential influences to begin using drugs that were person-centered. Much of the content of these programs was borrowed from in vogue educational themes that featured affective components. Although the content of programs in this tradition vary more from program to program, there are content themes that emerge and are useful for characterizing this approach generally. Enhancement of SeEf-Esteem and Self-Image Programs that focused on enhancing self-esteem or self-image have assumed that one reason for the onset of substance use is that young people who begin using drugs do so because of their poor self-perception. By providing self-concept building activities, such as goal-setting and personal problem-solving, the motivation for use was expected to be reduced. Stress Management Some programs have included stress management and stress reduction techniques such as deep muscle relaxation training and deep breathing. The idea behind this strategy is that drug use provides an escape from stress that can be accomplished without substance use. Values Clarification The essential characteristic of value clarification activities is the examination of an individual’s general values to discover the over-arching principles by which the person wishes to live his or her life. Drug use is then considered in light of these emergent values to demonstrate that drug use is inconsistent with the individual’s existing value structure. This strategy assumesthat students who are committed to a set of values will not use drugs as long as their values are kept salient. Decision Making Janis and Mann (20) noted that many behavioral choices are made on the basis of faulty decision-making algorithms. Since the consequences of substance use provide such clear incentives for not using, many affective education programs have included a rational decision-making component to minimize the opportunity for emotional drug use decisions. Goal-Setting Several studies have suggested that drug use onset is negatively correlated with an individual’s achievement motivation (21). This implies that for many who become substance abusers, there is a deficit in their ability to set and achieve positive goals. Programs have featured instruction in goal-setting as a means of enhancing an individual’s achievement orientation. Evaluations of affective education programs have been few and generally of poor quality, providing no strong support for the effectiveness of these strategies (13, 23, 37). One of the problems with the evaluated studies was a general lack of emphasis on behavioral outcomes. Furthermore, the few behavioral studies con- PROJECT SMART 139 ducted do not suggest this general approach to be effective. Some recent approaches have blended elements of both the social skills and the affective education approach [e.g., Botvin’s Life Skills Training (4)] with some successin preventing smoking and other substance abuse. However, insofar as a comparison between approaches is concerned, there has to date been no systematic investigation of one approach versus the other. There are several possible explanations for the lack of successof coping and affective approaches that deserve consideration. One of the features characterizing these studies is that the program focus is not specific to drug use prevention. That is, when talking about decision-making, decision-making about drug use, per se, was not always included. Contrary to what might be expected, values claritication activities rarely have tied the values that students specified to their potential drug use. In short, these programs typically featured diffuse strategies with general goals, rather than being speci&alLy targeted to prevention of drug use. PROJECT SMART The focus of Project SMART was to test a program based on the social influences model and a drug-specific program based on the affective education model for their relative effectiveness in preventing the use of the gateway drugs (27), tobacco, alcohol, and marijuana. The distinction between social influence and affective program content reflects a different set of assumptions about what are the most important determinants of drug use onset. Affective education is based on the premise that many of the reasons for drug use initiation have to do with personal shortcomings (e.g., low self-esteem) and personal motivations (e.g., to feel better). Social influence programs, on the other hand, are quite clearly derived from a model that emphasizes external factors, (e.g., role models and social pressures) as precipitators of drug use. Whereas the social influences program has enjoyed successin preventing the onset of tobacco use, there was no clear evidence that it could be effective in reducing the onset of other substance use as well. However, at least one study (32) has provided evidence suggesting that there may be a spill-over effect on alcohol and marijuana behavior from tobacco prevention programs. A second study may be interpreted similarly although the outcomes were less clear cut (24). Thus, a primary feature of the test was to determine whether or not a program that specifically targeted multiple substances using the social influences model would be successful. A second major concern was the possibility that programs developed in the affective area had not succeeded because of some feature that was lacking either in the directness of the connection between the program and not using drugs or in some other factor that may have enhanced the program sufficiently to make it successful. For example, since the use of same-age peers or slightly older role models had predominated in the social influences programs but not in the affective programs, it is possible that the affective programs failed not due to content but structure. Therefore, a second aim of Project SMART was to provide a test of affective approaches in which these dissimilarities were corrected. 140 HANSEN ET AL. METHOD Subjects and Experimental Design Of 63 junior high school complexes in the Los Angeles Unified School District available for assignment, 44 were randomly assigned to intervention and control conditions using a multi-attribute approach to enhance comparability (14). The results presented in this article will concern only the first cohort of seventh grade students who served as subjects beginning the first year of the project. The experimental design of this component of Project SMART is depicted in Table 1. In this cohort of the project, subjects were drawn from eight junior high schools. A total of 2,863 seventh grade students was involved in the study. Sex was equally represented with slightly fewer females (48.8%) than males (gender information was missing on 95 subjects). The ethnic grouping of subjects was as follows: 38.4% were hispanic; 30.5% were black; 21.7% were white; 5.8% were Asian; and 3.5% were other, unknown, or not classifiable. Curricula Two programs were created that reflected the theoretical positions described above. The content of each curriculum is summarized in Table 2. As can be seen, each generally reflects the paradigmic orientation of either a social influences or an affective education strategy. Each was balanced so as to maintain an equal emphasis on aspects of the teaching strategies that were felt to be important in the delivery of an effective substance abuse prevention program. For example, both featured the use of peer opinion leaders as assistants in delivering the program (2). Both strove to include activities that were about equal in terms of the balance between didactic presentation and active student involvement. Both had activities that were estimated by staff health educators and consulting classroom teachers to be of approximately equal enjoyability. Prior to implementation in treatment schools, both curricula had been pilot-tested. Procedures Based on the assignment to conditions procedure (14), schools were approached and solicited to participate in the study and either receive treatment or serve as no-treatment controls. Control schools subsequently received a program 1 for the following cohort of students. Schools were then scheduled to be pretested and (for treatment schools) receive one of the two Project SMART curricula in TABLE 1 EXPERIMENTAL DESIGN FOR PROJECT SMART COHORT 1” Group Schools Classes Affective 7th Social 7th Control 7th 2 2 4 24 25 35 Pretest WL, ws, 0, 0 X’s indicate the delivery of the Social/Affective program. O’s indicate a measurement. Post-test 1 Post-test 2 Q3 0, OS 09 09 09 141 PROJECT SMART TABLE 2 SUMMARY OF CURRICULUM COMPONENTS FOR Two SUBSTANCE ABUSE PREVENTION CURRICULA Session 1 2 3 4 10 11 12 Social curriculum Affective curriculum Introduction Format of the program Promoting group identification Motivations Motivators for using and not using drugs The nature of peer pressure Normative expectations Clarifying misperceived prevalence of drug use The nature of influence of friends Consequences Consequences of using and not using drugs Using consequences to resist pressure Resisting peer pressure Techniques to say “no” Scripting resistance to offers to use drugs Role playing Social situations that encourage drug use Role playing techniques Role playing resisting peer pressure to use drugs Adult influences Role playing resisting peer pressure to use drugs The nature of modeling Positive and negative parental influences Talking to adults about drugs Media influences Media awareness Advertising techniques Evaluating advertising influences Resisting media influences Entertainment influences Influences to use and not use drugs in entertainment Social activism in behalf of non-drug use in entertainment Alternatives The concept of alternatives Alternatives to drug use Saying “no” (practice) Positive friendships Qualities of good friends Techniques to develop and keep good friends Saying “no” (practice) Public commitment Videotaping of students commitment to say “no” to pressure to use drugs Introduction Format of the program Self-esteem/worth enhancement Motivations Motivators for using and not using drugs Sources of stress Alternatives Alternative solutions to problems Deep breathing Self monitoring Goal setting-Part I Goal setting essentials Drug use interference in personal goals Deep breathing (practice) Goal setting-Part II Setting a personal goal Deep breathing (practice) Consequences Monitoring personal goals Consequences of using and not using drugs Deep breathing (practice) Decision making Monitoring personal goals The decision making process Deciding about drug use Self-esteem The value of self-esteem Building self-esteem Complimenting others Assertiveness-Part I Defining assertive behavior Making assertive statements Muscle tension-relaxation Assertiveness-Part II Introduction to role playing Role playing assertiveness Muscle tension-relaxation Summary Achieving goals Role playing assertiveness Alternatives Public commitment Videotaping of students commitment to engage in alternatives instead of using drugs 142 HANSEN ET AL. either the fall or spring semester. Based on this schedule, entire schools were pretested during their fall or spring semester. Post-tests were collected from students during the subsequent school year, approximately 12 months after students completed their pretests. Pre- and post-test data were collected from students by means of paperand-pencil questionnaires and by the collection of saliva specimens administered by trained data collectors. The primary purpose for the collection of the biological samples was to enhance self-reports of cigarette and marijuana smoking behavior following the methods described by Evans et al. (9) and Luepker et al. (29). Questionnaire items assessed tobacco, alcohol, and marijuana use, demographics, and a number of other psychosocial constructs. The questionnaire is fully described in Graham et al. (15). Tobacco, alcohol, and marijuana use questions assessed lifetime use, 30-day use, 7-day use, and customary use. The same questionnaire was administered at all three points of data collection. Subsequent to pretesting, students in schools assigned to the Social and Affect conditions received the appropriate curriculum over a semester period, the program was delivered 1 day each week. Staff health educators alternated with regular classroom teachers in delivering the 12 sessions of each program. Prior to implementation, classroom teachers were given a l-day training workshop to provide them with essential information and skills to deliver the aspects of the program they were assigned to deliver. RESULTS Index Construction and Analysis Plan Data were aggregated into classroom scores so that the data from individuals who were in the same classroom at pretest were collapsed to create classroom scores that formed the basis of all analyses. The analyzed sample thus consisted of 36 Control classrooms, 25 Social classrooms, and 24 Affective classrooms. Two separate data sets were constructed. The first included subjects who were present at the pretest and initial post-test (Data Set l-2); the second included subjects who were present at pretest and the final post-test (Data Set l-3). Tobacco, alcohol, and marijuana items were each combined into “use” indices similar to the Minnesota Smoking Index (35) with pretest classrooms as the aggregating unit. The index essentially reduces a number of variables into a score that represents average number of cigarettes, alcoholic drinks, or marijuana joints used per student per week. These indices were analyzed separately to assess impact of programming on each substance use with two planned comparisons that compared the Social program vs Controls and the Affective program vs Controls. Index data were analyzed using analysis of variance and analysis of covariance using pretest scores as the covariates. Additionally, dichotomous 30-day use data were analyzed using Fisher’s Exact test. Two sets of analyses were conducted on index data. The first involved the analysis of data for only those subjects who did not use a given substance in the 30 days prior to the pretest. The second used pretest scores as covariates and included data from all subjects in the sample irrespective of their pretest use. Both PROJECT SMART 143 approaches were adopted to limit the bias that pretest difference might have on interpreting outcome analyses. Pretest Comparability Each index was examined to determine the equivalence of planned comparison groups at pretest. There were significant pretest differences between Social curriculum and Control subjects’ alcohol use in both Data Set l-2 [F(1,329) = 12.55, P < 0.0011 and Data Set l-3 [F(1,329) = 3.28, P < 0.081 with Social subjects reporting less drinking than Control subjects in both cases. Control and Social subjects differed on tobacco in Data Set l-2 [F(1,329) = 3.76, P < 0.06] but not in Data Set l-3 [F(1,329) = 1.21, not significant]. There were no pretest differences for either data set for marijuana use. There were no differences between the Affective curriculum and Control subjects’ alcohol use, tobacco use, or marijuana use. Thirty-day use scores were also examined to determine pretest comparability. In Data Set 1-2, there were significantly more users among Control subjects than among Social subjects (x2 = 12.3, P < 0.005). There were also more subjects in the Control condition than in the Social condition who reported drinking alcohol (x2 = 19.0, P < 0.0001). In Data Set 1-3, the use of tobacco among all subjects (x2 = 5.8, P < 0.02) and alcohol use among all subjects (x2 = 5.1, P < 0.05) was also greater among Control than Social subjects. The prevalence of alcohol use among Affective subjects was higher than among Control subjects (x2 = 6.0, P < 0.02). No other pretest comparisons were significant. Effects of Programming The results of comparison analyses examining the effects of programming on index values are presented in Table 3. As can be seen, a number of significant differences emerged. Analyses of means indicate that for both tobacco and alcohol, onset among non-users at pretest, and use by all available subjects, was less among those who received the Social curriculum. For example, index smoking means at eighth grade for the seventh grade non-smokers in the Social condition was 0.397 whereas the comparable Control subjects’ smoking index score was 0.569. Index smoking means for the analysis which included all subjects yielded scores of 0.544 and 0.888, respectively, for Social and Control subjects. Similarly, onset of alcohol use by eighth grade was 0.267 for Social subjects compared with 0.390 for Controls. The prevalence of alcohol use was also lower among subjects in the Social condition than among those in the Control condition, with alcohol index means of 0.351 and 0.631, respectively. Marijuana index scores for pretest non-users were only slightly lower among Social program students (0.202) compared with Controls (0.260). Finally, marijuana indices for analyses including all Social and Control subjects, respectively, were 0.259 and 0.421, again indicating lower use among those who received the Social curriculum. Except for marginal results for tobacco and alcohol, those who received the Social program were not observed to have reduced use at the second year post-test. The Affective program appeared to have a negative impact, with all analyses at 144 HANSEN ET AL. TABLE 3 RESULTS OF ANALYW OF COVAR~ANCE AND PLANNED COMPARISONS EXAMINING THE IMPACT OF PROJECT SMART ONTHE INCIDENCEANDPREVALENCEOFTOBACCO, ALCOHOL,AND MARIJUANA USE Post-test 1 Post-test 2 Behavior Analysis Comparison F P d” F Tobacco Incidence Affect/control Social/control Affect/control Social/control Affect/control Social/control Affect/control Social/control Affect/control Social/control Affect/control Social/control 6.83 2.36 0.009 - 0.1 + 4.00 4.99 1.95 0.05 0.03 + 30.52 2.54 21.44l 2.13 0.2 - 2.34 7.56 0.1 0.006 + - 3.71 0.06 + 8.39 0.55 4.22 2.88 0.004 0.5 0.04 0.09 - Tobacco Prevalence Alcohol Incidence Alcohol Prevalence Marijuana Incidence Marijuana Prevalence + 2.14 0.93 13.18 3.57 13.19 0.00 15.37 0.11 P d 0.0001 - 0.1 0.0001 0.2 + + 0.2 - 0.3 0.0003 0.06 0.0003 0.9 0.0001 0.7 + - n Direction of difference for significant and marginal findings. A plus (+) indicates a positive program vs control outcome. A minus (-) indicates a negative program vs control outcome. the first and second year follow-up measures indicating negative programmatic effects. By the final post-test, these effects were quite pronounced. For example, the index mean for tobacco at final post-test for Affective students was 1.508 while the mean for Controls was 0.878. The index means for alcohol at the final post-test were 1.171 (Affective) and 0.724 (Control). Likewise, means of marijuana use for these two groups were 0.846 and 0.480, respectively. We also considered the proportions of non-users who began use at various levels, perhaps a more meaningful indicator of onset. Figures 1, 2 and 3 present rates of onset among those who were non-users at pretest. As can be seen, these findings generally corroborate those from index analyses. Figure 1 reveals that the onset of tobacco use was significantly lower among students who received the Social program at post-tests 1 and 2; 13.0% compared with 18.2% for controls at the first post-test, and 11.8% compared with 17.8% at the second post-test. This translates into a 37.5% reduction in smoking onset 1 year after the program and a 32.4% reduction in onset 2 years after the program that can be atttributed to the Social program. It appears, furthermore, that the effect of the Social program was greatest in reducing onset of heavier smoking. For example, at the level of five or more cigarettes in the preceding 30 days, the reduction was about two-thirds at the first post-test (5.3% vs 1.7% for Control and Social conditions, respectively), and three-fourths by the final post-test (6.0% vs 1.4%). There was a tendency for drinking onset to be less among subjects in the Social condition than for Control subjects (see Fig. 2). This difference was significant at the level of two or more drinks in the preceding 30 days (6.0% vs 9.9%, or a 39% reduction), but not at lower levels of drinking. The same pattern of effect continued at the final post-test with treatment effects becoming clearly significant only at the level of two or more drinks (6.8% vs 10.3%, a 34% reduction). 145 PROJECT SMART YEAR 3 IMPARISONS CvsA ens SHEIKS EXACT ROBABlLlTlES h) . mm I.. I.. . . . . . . . . . . . . . . . . 1 ONSET AT YEAR 2 m ONSET AT YEAR 3 ... I ..... .... pco.15 p c 0.10 pco.05 p-co.01 p c 0.001 FIG . 1. Onset of tobacco use among non-users at Year 1. Comparing control (C), affective (A), and social (S) conditions. Figure 3 reveals a significant treatment effect at the first post-test for marijuana use onset at all levels combined (10.9% vs 6.8% for the Control and Social conditions, respectively). This amounts to a 33% reduction in marijuana use onset. By the final post-test, however, this difference was no longer evident. In contrast to these findings for the Social program, proportionally more subjects who received the Affective program had used all three substances at both waves. Compared to Controls, those receiving the Affective program had 20.1 and 86.4% increases in tobacco use, 30.9 and 42.4% increases in onset of alcohol, and 47.3 and 74.2% increases in marijuana use at post-tests 1 and 2, respectively. By the final post-test, onset of tobacco use was greater in the Affective than the Control condition across the entire range of usage levels (see Fig. 1). For alcohol the effect was significant up through two to four drinks in the preceding 30-day HANSEN ET AL. I I-1 ONSET AT YEAR 2 m ONSET AT YEAR 3 - I I I S-10 DRINKS OR MOHE I 11 OR MORE ORINKS YEAA 2 COMPARISONS CnA ens . . . rV . . N . . rnD . . YEAR 3 COMPARISONS C YI A c 1s s . l mm FlsftEfrs EXACT PROBAllLlTlES m p.zB.16 pc 0.10 p < 0.05 l . . . . . P<O-10 l mmm p-z O.DOl FIG. 2. Onset of alcohol use among non-users at Year 1. Comparing control (C), affective (A), and social (S) conditions. level (see Fig. 2). For marijuana the effect was significant up through 5-10 times in the preceding 30 days (see Fig. 3). These data were also examined for the effects of programming on those who were already using substances at pretest. There appeared to be small programmatic effects on reducing subjects’ tendencies to use more, with Social subjects who were using alcohol at pretest less likely than similar Controls to increase their use by the final post-test (see Table 4). Although the rate of marijuana use increase was 60.1% lower among Social subjects when compared with Controls, numbers were too small for this to result in a significant difference. On the other hand, subjects who used tobacco, alcohol, or marijuana at baseline and received the Affective curriculum were more likely than similar Controls to increase their use of these substances by both post-test occasions (see Table 4). A similar analysis examining reductions in use among pretest users was also conducted (see Table 5). In this analysis, those who received the Affective pro- 147 PROJECT SMART I----lOftSET AT YEAR 2 ONSET AT YEAR 3 C A S I TIME OR MORE YEAR 2 DMPAIIISOWS CnA ens . . . . . VEAR 3 OMPAAISOWS CnA ens . . . . ISHER’S EXAC ROSA8IllflE! N , < 0.15 p-z 0.10 . . p < 0.05 mm. ,<o.ot . . . , < 0.001 . FIG. 3. Onset of marijuana use among non-users at Year 1. Comparing control (C), affective (A), and social (S) conditions. gram appeared to be more likely to reduce their tobacco and alcohol use at the initial post-test. This trend was not observed at the final post-test. Interestingly, subjects who received the Social program reduced their alcohol use less than Controls at the final post-test; this was in contrast to the positive effects of this program on preventing onset. Attrition Analyses It has been noted (17) that attrition is a serious threat to the validity of prevention research. Attrition can limit the degree to which findings can be generalized to all participants, particularly if one type of subject is more likely to drop out of the study. Further, if there is differential attrition by condition or if there is a behavior status by condition interaction in attrition such that different kinds of 148 HANSEN ET AL. TABLE 4 INCREASED USE AMONG USERS IN YEAR 1 COMPARING AFFECTIVE AND CONTROL AND SOCIAL AND CONTROL WITH SIGNIFICANCE BASED ON FISHER’S EXACT PROBABILITIES Proportion who increased use Substance Tobacco Alcohol Marijuana * ** *** **** P P P P Group Post-test 1 Post-test 2 Affective Control Social Affective Control Social Affective Control Social so.s** 38.2 30.8 37.3*** 22.3 28.2 42.3 34.5 15.4* 49.3* 39.2 38.9 48.0*** 37.7 22.6** 55.3 41.9 16.7 < 0.15. < 0.10. < 0.05. < 0.01. people are dropping out of different conditions, the internal validity of a study is brought into question. Overall, attrition rate of this study was 37% from pretest to initial post-test and 52% from pretest to final post-test. This includes inter- and intrasystem transfer as well as school dropouts. The analyses that follow were appropriate to this study. Differences between those missing and those present at follow-up. There was no differential attrition by sex at initial post-test (x2 = 0.76, n.s.). There were slightly more males (53.8%) than females (49.7%) who dropped out by final posttest (x2 = 4.66, P < 0.03). Differential attrition occurred by ethnicity at both REDUCED USE AMONG CONTROL TABLE 5 USERS AT YEAR 1 COMPARING AFFECTIVE AND CONTROL AND SOCIAL WITH SIGNIFICANCE BASED ON FISHER’S EXACT PROBABILITIES Proportion of quitters Substance Tobacco Alcohol Marijuana *Pco.ls. ** P s 0.10. *** P s 0.05. **** P c 0.01. Group Post-test 1 Post-test 2 Affective Control Social Affective Control Social Affective Control Social 66.3*** 54.5 42.3 58.8*** so.4 54.3 56.6 61.8 38.4* 57.3 53.7 61.1 69.8 63.3 43.8*** 61.5 51.6 28.6 AND PROJECT SMART 149 post-tests (x2 = 97.11, P < 0.0001 and x2 = 20.15, P < 0.0001, respectively) with black students most likely not to be found at follow-up (49 and 56%), and hispanits (37 and 55%), Asians (29 and 42%), and whites (28 and 48%) a little less likely to drop out. The baseline smoking index score of those present at follow-up was significantly lower than for those who were not present at the initial [F(1,2753) = 21.83, P < O.OOOl] and final post-tests [F(1,2750) = 26.44, P < O.OOOl]. Baseline smoking index scores for those present and not present at the initial post-test were 0.684 and 0.439, respectively, and for the final post-test were 0.655 and 0.395. The same pattern held for the marijuana index scores comparing droppers and stayers at initial [F(1,2482) = 11.28, P < 0.00081 and final post-test [F(1,2480) = 29.95, P < O.OOOl]. Marijuana use was greater among droppers at each post-test (0.313 and 0.326) than among stayers (0.186 and 0.131). There were no significant differences between followed and nonfollowed subjects on the pretest alcohol index scores at the initial post-test [F(1,2658) = 1.15, P > 0.251. At the final post-test, however, nonfollowed subjects had significantly more pretest alcohol use [F(1,2655) = 7.76, P < 0.0061. Baseline index scores for alcohol use were 0.423 and 0.318 for absentees and those present at the final post-test, respectively. Thus, as might be expected from previously reported research (14), those who used substances were more likely to drop out of the study. Differences in rates ofattrition. There was differential attrition by condition. At the initial post-test, there was greater attrition among those in the Social condition (45%) than among those in the Control (39%; x2 = 7.12, P < 0.008). There was less attrition among Affective subjects (30%) than among Controls (x2 = 18.60, P < 0.0001). At the final post-test, there was equal attrition among Control (60%) and Social (60%) subjects and less attrition among those who received the Affective program (37%) than among Controls (x2 = 116.58, P < 0.0001). Condition by attrition status interactions. The differences in rates of attrition by condition have important implications for the internal validity of the study primarily if these differences are disproportionately high among those at greatest risk for onset. Interactions between condition and attrition status on tobacco, alcohol, and marijuana index scores were used to test for differences in the baseline substance use of dropouts among conditions. These analyses followed those of outcome analyses for each of the planned programmatic comparisons. There were no significant condition and attrition status interaction effects for any behavioral outcome, suggesting no tendency for higher risk subjects to be lost to follow-up in one or another experimental condition. Thus, while there was greater attrition among Social subjects compared with Controls at the initial post-test, the threat to internal validity posed by this differential attrition among conditions appears to be mitigated by the fact that this attrition was not related to substance use. The rate of attrition by condition and the character of those dropping out yielded inconsistent results. To determine if there was an overall threat of differential attrition, mean pretest use scores of dropouts were multiplied by rates of attrition for each of the dependent variables which were then analyzed using analysis of variance. At the first post-test, only two analyses approached significance. For alcohol use, Social subjects’ attrition/use scores (0.109) were lower 150 HANSEN ET AL. than the scores for Controls (0.152; F(1,959) = 1.97, P = 0.16). A similar pattern held for marijuana use with Social subjects’ attrition/use scores (0.070) less than those for Control subjects (0.122; F(1,893) = 2.57, P = 0.11). At the final post-test, two attrition/use analyses reached significance while two were marginally significant. Attrition/use scores were less for Social dropouts (0.274) than for Control dropouts (0.324; F(1,1431) = 4.88, P = 0.03). For alcohol, attrition/use scores for dropouts from the Social condition were less (0.121) than those for Controls (0.267; F(1,1362) = 14.96, P = 0.0001). The marijuana analysis yielded similar findings with Social subjects’ attrition/use index again lower (0.121) than that of Controls’ (0.178; F(1,1271) = 2.32, P = 0.13). Finally, results for alcohol comparing Affective subjects’ attrition/use scores (0.214) yielded marginally significant results compared with Controls (0.267; F( 1,1362) = 2.01, P = 0.16). Thus, despite an increased rate of attrition among Social subjects, the overall picture suggests that there was either no effect of attrition on end results, or that if there was an effect, it was to mask slightly the effectiveness of the Social program. In the end, there is no strong reason to suspect that the results obtained were attributable to attrition artifacts. DISCUSSION The results of this study to date suggest that the most efficacious program for reducing drug abuse onset is a program that features social infhrences resistance training as a major focus. The Social curriculum, which included content that addressed peer, parental, and mass media influences to use drugs, reduced the onset and prevalence of tobacco, alcohol, and marijuana use at the l-year followup. There was marginal evidence that tobacco use among baseline smokers was reduced by the time of the final post-test for pretest non-users. The Affective program on the other hand apparently increased use compared with Controls, with increases becoming more pronounced over time. There are several limitations to this study that need to be considered in interpreting these findings. There was less drinking at baseline among subjects who received the Social curriculum. It is possible that the social milieu in these schools was less conducive to drinking and possibly to other forms of drug use as well, and that there was a difference among conditions at pretest. Our approach to analysis was implemented specifically to reduce such threats. While analysis of covariance cannot correct for pretest differences perfectly, there is enough convergence among the various analyses to suggest that a real effect was observed. Further, since baseline tobacco and marijuana use levels were equivalent, this lends additional support to the interpretation of a real treatment effect. Attrition analyses resulted in partly predictable findings. Except for their alcohol use, those not present at follow-up were more likely to use substances than those tested again, a finding that has been observed previously (17). The Social condition group experienced the greatest attrition. However, there was not any differential attrition by level of risk for drug use onset. Thus, the most potentially damaging explanation for the differential attrition observed was nullified. While there may always be some suspicion about differential attrition that went unde- PROJECT SMART 151 tected, based on the tests conducted, there does not appear to be a significant threat of attrition that can be directed at the outcome data. The observed marginal effectiveness of the Social program for alcohol as well as tobacco reaffirms the social pressures resistance training paradigm that has been advocated now for over a decade as a promising means of preventing the onset of substance abuse. While no single study can provide definitive proof that social pressure resistance training works for preventing the onset of all gateway substances, these results are supportive of the approach and call for further experimental verification. However tentative these results, there has already been widespread adoption of the Project SMART approach to drug abuse prevention. For example, Project DARE, a program derived in large part from Project SMART but which is delivered by police officers, is currently being implemented in many cities (7, 34). Additional experimental programs, (e.g., the RAND drug abuse prevention curriculum, Project ALERT) also use the same approach as Project SMART (36). In light of the popularity of this approach, continued research on the effectiveness of the program is important (25). Research on refinements to the program continues to be conducted. While the Social approach received some support, the Affective approach as a stand-alone program for drug abuse prevention received none. In part, this may have been the result of the character of the program. It is possible for instance that subjects received mixed messages in this program and may have actually come to see drugs as a means of coping with stress and enhancing self-esteem. It was also apparent from reports of the staff health educators delivering the program that the Affective program was more difficult to implement, at least in comparison to the Social program. It is also possible that the apparently harmful effect of the Affective program may be an artifact of a control group that performed abnormally. In evaluations of prevention programs, it is expected that control groups will have a considerable onset, reflecting the normal pattern in our society. In this case, the control group’s onset was actually less than expected. The subsequent cohort of students in the control schools received versions of the Social and the Affect programs. It may be that there were “trickle up” effects of these programs. Alternately, it may have just been that the particular controls selected were not equivalent to either of the treatment condition schools. The result of either of these alternatives is that the Affective program would appear to be simply ineffective at prevention. The Social program on the other hand would appear to be relatively more effective. Whatever the explanation, the approaches used in that program, including goal setting, behavioral alternatives, stress management, and self-image enhancement did not appear to contribute to prevention and may have enhanced experimentation. Research examining this approach in the past also has failed to show positive results. 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