Enhanced diagnostic capabilities for health care practitioners in the detection of A l z h e i m e r ’s d i s e a s e a n d r e l a t e d neurological disorders. “NeuroQuant is a powerful tool that allows me to gauge whether a patient’s brain atrophy is abnormal for his or her age. This atrophy has been shown to be a sensitive marker of Alzheimer’s Disease.” Michael S. Rafii, MD, PhD Director, Memory Disorders Clinic Assistant Professor of Neurosciences Associate Medical Director, Alzheimer’s Disease Cooperative Study Attending Neurologist, Shiley-Marcos Alzheimer’s Disease Research Center University of California, San Diego brought to you by Age-Related Atrophy Report contains the absolute and DynaSuite Neuro with NeuroQuant A Breakthrough Application relative volumes of the hippocampus and inferior lateral Invivo has partnered with CorTechs Labs to provide in dementia patients. The resulting values are automatically NeuroQuant quantitative analysis on its D ynaSuite Neuro compared to age-appropriate reference distributions. ® ventricles, structures that typically show significant atrophy plat form. Invivo is of fering NeuroQuant as an option to compliment the advanced applications of D ynaSuite Neuro which include per fusion, dif fusion and functional MRI Advances in processing of MRI data have lead to the (fMRI). Data is automatically processed and displayed development of applications that can automatically quantify in predefined layouts which are customizable for each the volume of key neuro structures. These results can aid physician’s preference. A simplified user inter face provides in the assessment and treatment of Alzheimer’s disease, the neuroradiologist with the tools to analyze cases quickly epilepsy and other neurological disorders. and easily. Invivo of fers extensive sales, ser vice, and “NeuroQuant provides me with the impor tant volumetric MRI quantification that helps me to assess Alzheimer’s and other dementia patients. It is fully automated and is easy to add into a routine practice” applications support to provide the comprehensive NeuroQuant takes a high-resolution 3D T1-weighted, solution our customers expect. sagittal, non-contrast-enhanced MRI scan and automatically returns a new full-volume spatially corrected and anatomically labeled dataset along with two printable patient repor ts containing the absolute and relative volumes of the hippocampus, temporal horn, and other structures. NeuroQuant is a breakthrough application that can make James Brewer, M.D., Ph.D. Assistant Professor Departments of Radiology and Neurosciences University of California, San Diego quantitative MRI measurement a routine part of clinical practice. It brings sophisticated, accurate, and fully automated MRI post-processing capabilities for the physician. This software provides neurologists, radiologists, and clinical researchers with a convenient and cost-effective means of quantification. General Morphometr y Report provides the absolute and relative volumes for the right and left-side of the following brain structures: Forebrain Parenchyma, Cortical Gray Matter, Lateral Ventricle, Inferior Lateral Ventricle, Hippocampus, Amygdala, Caudate, Putamen, Pallidum, Thalamus and Cerebellum. It also provides an Asymmetr y Index (defined as the difference between left and right volumes divided by their mean). Invivo Value-Added Solutions better images mean better results Products Service Support Education A world leader in innovative MRI solutions, Invivo is focused on your clinical needs. We take pride in providing the best in customer support and clinical education, to create a true partnership with you. Realizing that better support means better results, our TechPoint customer care provides: Remote technical support, for fast, easy support no matter where you are On-site applications training, to keep you on top of applications and updates • Rapid turnaround time on repairs, to reduce down-time in your practice • Physician to physician workshops • Marketing toolkits • • D ynaSuite Neuro with NeuroQuant integration. Key Features Include: • Fully Automated Segmentation of MRI exams of the whole brain and regional volumetric quantification of structures • Automatic Correction for image artifacts including gradient nonlinearities and RF field inhomogeneities • Atlas-Based image registration, anatomical segmentation, and volumetric • High Validity -- Automated segmentation shown to be highly consistent with that quantification of the hippocampus, ventricles and other brain structures performed by human expert neuroanatomist • High Reliability -- Making results ideal for longitudinal follow-up and tracking of disease. • Numerical Results are automatically compared to normative data to highlight atrophy greater than expected from normal aging For more information about DynaSuite Neuro with NeuroQuant or any of the Complete Solution products from Invivo, please call us at 1-800-331-3220, or visit our website at www.invivocorp.com. • Medial Temporal lobe volumes from NeuroQuant shown to be sensitive to MCI and early AD in multi-vendor, multi-site MRI data NeuroQuant provides two reports from its volumetric analysis, an age related report and a general morphometr y report as shown below. DynaSuite Neuro provides special hangings for viewing each repor t with multi-planer images of the user’s choice. Invivo Corporation Gainesville, FL U.S.A T: 877-INVIVO1 T: 407-275-3220 E: [email protected] www.invivocorp.com Europe: T: +31 (0) 499 378624 [email protected] NeuroQuant ® is a re gistered trademark of CorTechs Labs, Inc. La Jolla, CA. ©2010 Invivo Corporation All Rights Reser ved. 580261 Rev. 01
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