NAME_______________________________________
CircleOne:A1A2
SCORE_____________/16
MULTIPLECHOICE
Circlethebestanswerforquestions1-10(1pteach)
1. ApieceofdoublestrandedDNAhas30%A,whatwillbethe%ofG?
a. 30%
b. 40%
c. 20%
d. 70%
e. notenoughinformationtoanswer
2. YouhaveapieceofDNAwiththesequenceATGC.Fromthisyouknow,
a. Aisatthe5’end
b. Aisatthe3’end
c. Acouldbeateitherthe5’endorthe3’endofDNA
d. Youhaveapalindromicsequence
e. Noneoftheabove
3. Whichofthefollowingbasespairswithguanine?
a. Adenine
b. Guanine
c. Cytosine
d. Uracil
e. Thymine
4. Thenitrogenousbaseislinkedtotheriboseordeoxyribosesugarviaa
a. Glycosidicbond
b. Amidebond
c. Hydrogenbond
d. Phosphoanhydridebond
e. Phosphodiesterbond
5. GenomicDNAis_______resultingintheproductionof_______.
a. TranscribedmRNA
b. Translated,tRNA
c. Transcribed,DNA
d. Translated,protein
e. Replicated,mRNA
6. _______istheadaptorthatiskeytoconvertingthetripletcodonsofmRNAintothe
proteinpolymers.
a. tRNA
b. rRNA
c. mRNA
d. siRNA
e. lcRNA
7. Whichofthefollowingstatementsaboutdouble-strandedDNAisfalse?
a. Thebackbonecontainsalternatingribosesugarandphosphategroups.
b. Thetwostrandshaveanantiparallelorientation.
c. Thehelixhastwogroovescalledthemajorgrooveandtheminorgroove.
d. Thebasesareontheoutsideofthehelix.
e. Thestrandsareformedbynucleotideslinkedtogetherviaphosphodiester
bonds.
8. Inthepicturebelow,arrowlabeled1correspondsto______andarrow2corresponds
to_________.
a. Replication,transcription
b. Translation,transcription
c. Mutation,replication
d. Transcription,replication
e. Transcription,translation
9. Inthepicturebelow,whichlabel(s)ontheleftrefertothetemplatestrand?
a. 1
b. 2
c. mRNA
d. both1and2aretemplatestrands
e. both1andmRNAarethetemplatestrands
10. WhichofthefollowingstatementsareTRUE?
a. ThemRNAistranslatedfrom5’tothe3’end
b. ThemRNAistranslatedfrom3’to5’end
c. Duringtranscription,themRNAissynthesizedinthe3’à5’direction
d. AandCarebothtrue
e. BandCarebothtrue
2
SHORTANSWER.Followdirectionswitheachquestion.
11. Forthebasepairshownbelow,answerthefollowingquestions.(6pts)
O
NH2
N
N
HN
N
N
O
N
O
O
O
H
H
3
O
O
H
H
H
H
H
H
H
O
H
a. Shownaboveis(circleallthatapply).
Adenosine Guanosine Cytidine
Uridine
Thymidine
b. Drawhydrogenbondsbetweenthebasesasdashedordottedlines.
c. CIRCLEthegroupthatisthemajordifferencebetweenuridineandthymine.
d. Drawanarrowtotheglycosidiclinkageofthepurine.
e. Drawasquarearoundthe5’-carbonofthepyrimidine.
12. ThefollowingpieceofdoublestrandedDNAencodesaveryshortpeptide.Inthespace
below,writethesequenceofmRNAthatwouldbesynthesizedbyRNApolymerasefrom
thispieceofDNAifthebottomstrandisthetemplate.Thenwritetheproteinsequence
inone-lettercodethatwouldbesynthesizedbytheribosomefromthatmRNAusingthe
firstreadingframe(useGeneticCodeTablebelow).(0pts)
5’- ATGGCTGGGTGCTTTTAA-3’
3’ –TACCGACCCACGAAAATT-5’
mRNAsequence:
AUG GCU GGG UGC UUU UAA
Proteinsequence:
MAGCF