Roche Diagnostics
VENTANA Research Applications
First edition
DISCOVERY
The VENTANA DISCOVERY product line provides best-in-class
instrumentation and reagents to the life sciences research market. The
DISCOVERY team fosters strategic partnerships with key market influencers
that support high medical value innovations in IHC, ISH, FISH and IF
research, ultimately advancing medical science.
The DISCOVERY business serves customers worldwide, anywhere tissuebased innovators are found. We are ready to partner with you to achieve your
research objectives.
www.ventana.com | www.roche.com iii
Empowering | Automation
Empowering | Medical Value
Empowering | Results
iv We innovate staining platforms and workflow solutions that enable
you to handle slides individually, even at your highest volumes. You
can count on the people who created the first fully automated IHC,
ISH and FISH slide staining capabilities to deliver the highest level of
sophistication and consistency to your lab.
Guided by science, we have developed the industry’s largest, most
advanced portfolio of pre-diluted, ready-to-use reagents to support
your lab. All of our reagents are specially optimised for use on our
cutting-edge instrumentation, to maximise the efficiency, precision
and quality of all your research assays.
Our fully integrated solution is a comprehensive set of the tools you
need to deliver the results you want.
Now available | the lab of the future
Experience the ease and confidence that comes with optimised, ready-touse reagents, fully-integrated, highly flexible automated staining platforms
and world-class technical support, training and customer care—all from a
strategic partner who is uniquely positioned to deliver the most advanced
research staining solutions to any lab, anywhere in the world, right now.
www.ventana.com | www.roche.com v
vi Table of Contents
IVD Companion Diagnostics Services 1
Translational Diagnostics
2
IHC and ISH 5
DISCOVERY ULTRA independent slide staining system
DISCOVERY XT automated slide staining system
7
11
Detection Chemistries
14
Primary Antibodies
25
Molecular Probes
31
Ancillary Reagents
32
H&E 45
SYMPHONY fully automated H&E system
47
Digital Pathology 51
iScan Coreo slide scanner
53
Virtuoso image management software
57
Customer Services 61
Technical Consultation Centre
63
Education and Training
67
Appendix 71
Index72
Disclaimer
While we have made every effort to provide accurate and complete information in
this catalogue, various data may change or be updated by the company at any time
without notice. The company provides no warranty, express or implied, as to the
accuracy, reliability or completeness of furnished data. Photos are an indication only
and do not guarantee staining results.
Some products may not be available in your country. Check with your local Roche
representative for the availability of products in your region and the applicable
General Terms and Conditions.
www.ventana.com | www.roche.com vii
viii IVD Companion Diagnostics Services |
Translational Diagnostics 2
www.ventana.com | www.roche.com 1
IVD COMPANION DIAGNOSTICS SERVICES | Translational Diagnostics
Translational Diagnostics
Innovative thinking, hard work and commitment have brought you
within reach of the answers you need. Through our Translational
Diagnostics Group (TDx), we help you overcome the challenges that
remain on the road to drug approval.
We’re there through every step of your
development journey.
Only VENTANA TDx offers you proven expertise in all
four key components required to successfully integrate
IVD systems on automated instrument platforms:
• Biomarker assay development
• Operational execution
• Regulatory and clinical experience
• Commercialisation expertise
Our operational processes integrate design control,
GMP manufacturing and a strong supply chain. We
offer exceptional ongoing service from dedicated
lab, marketing, sales and reimbursement support
organisations.
biomarker assay
development
Commercialisation
expertise
operational
execution
regulatory and
clinical experience
2 Translational Diagnostics | IVD COMPANION DIAGNOSTICS SERVICES
Drug development (clinical trials)
Phase 1 >
Safety
Phase 2 >
Treatment effects
Phase 3 >
Confirmation of clinical benefit
Diagnostic milestone
Stage 1 >
Develop
prototype
assay
Stage 2a >
Develop PMA
ready
IVD product
Stage 2b >
Perform
retroanalysis of
Phase II samples
6-8 weeks
8-12 months
6-7 months
Phase 3 >
Conduct
diagnostic
clinical trial in
parallel with
therapeutic trial
2-3 years
We’ll take you anywhere you want to go.
• We have a robust global installed base in North America,
Europe, Australia and Japan, with rapid expansion into
Asia (including China) and Latin America
• Direct global operations in more than 50 countries
• Active in 150 countries
Prepare and
submit PMA
filing with
FDA. Co-filing
with NDA for
simultaneous on
label approval of
PMA
We offer you the advantage of strength in numbers.
• 7,000+ instruments installed in anatomic, reference,
pharma research and clinical research labs around
the world
• 10+ years experience working with top 25
biopharmaceutical companies and CROs
• 50+ country network of regulatory associations to
ensure a smooth progression through clinical validation,
clinical trials and submission
www.ventana.com | www.roche.com 3
4 IHC and ISH |
DISCOVERY ULTRA independent slide staining system 7
DISCOVERY XT automated slide staining system 11
Detection Chemistries 14
Primary Antibodies 25
Molecular Probes 31
Ancillary Reagents 32
www.ventana.com | www.roche.com 5
The products that appear on this page are IVD (for in vitro diagnostic use).
6 DISCOVERY ULTRA independent slide staining system | IHC & ish
DISCOVERY ULTRA
independent slide staining system
Beyond traditional staining platforms that require you to fit your chemistries
to their systems, the VENTANA DISCOVERY ULTRA system is adaptable
to a broad array of tissue testing capabilities. From developing novel assays
on low-expressing biomarkers to enabling the highest level of experimental
complexity, DISCOVERY ULTRA system accelerates IHC and ISH research,
offering innovators significant improvements in ease of use, workflow and
system flexibility.
Flexibility
• Run 30 completely independent protocols for improved
workflow
• Choose your own antibodies, probes, pretreatments,
fluorescence, linkers and blockers
• Select the detection chemistry that best meets your needs
Reproducibility
• Fully automated slide processing; baking through staining
• Ready-to-use optimised reagents
• Apply precise heating to each slide individually for greater
control over IHC/ISH reactions
• Save up to 5,000 protocols for better assay development
recording/tracking
Features and benefits
Advanced deparaffinisation and pretreatment options
• Improved staining quality and morphology
• Increased signal-to-noise ratio
• More reliable results and easier to interpret slides
30 independent reaction chambers
• Speed method development by employing a higher
level of testing complexity within a single run
• Run manual applications and fully
automated protocols simultaneously
• Conduct IHC and ISH dual stain sequences
on the same slide or side-by-side
Ability to add and remove slides while system is running.
• Save valuable development time
• Incubate offline for maximum flexibility
• Refrigerate heat-sensitive antibodies offline for
maximum potency.
Flexible buffers and bulk reservoirs
• Increase staining capacity without replenishing bulk fluids
• Add bulk reagents while system is running to
enhance workflow
For Research Use Only. Not for use in diagnostic procedures.
www.ventana.com | www.roche.com 7
IHC & ish | DISCOVERY ULTRA independent slide staining system
Specifications
General characteristics
Capability
•
Automated baking, deparaffinisation, cell conditioning and staining, including IHC, ISH, FISH, FITC,
multiparameter staining (dual, triple); titration
Slide drawers
•
30 independent slide reaction chambers with dedicated bulk reagent supply lines and individual slide
heaters
Reagent carousel
•
35 reagent positions
Slides
•
25 x 75 mm, 1 x 3 inches or 26 x 76 mm
Modularity
•
1 to 8 staining systems may be controlled from one VENTANA software computer system
Water quality
•
(S/B NCCLS) Type II water or equivalent
Bulk reagents
•
Up to 7 different bulk reagents in 3 to 6 litre on-board containers
Configuration
•
Free standing
Certifications
•
CSA and CE compliant (research use only)
•
400 BTU/Hr idle, 1000 BTU/hr running
Environmental requirements
BTU/hour output
Room temperature
•
20 ºC to 32 ºC
Humidity
•
10% to 90%, non-condensing
Location
•
Flat, level surface. No direct sunlight or drafts. Remove from direct
source of heat and moisture.
Size - closed
(Width x depth x height)
•
111.76 x 84.07 x 158.50 cm
Weight
•
294.8 kg
Clearances
•
Top 38.1 cm
Sides 10.2 cm
Rear 15.2 cm
•
Ambient to 95 ºC
•
230 VAC ± 10%
Physical characteristics
Temperature control
Slide temperature range
Electrical specifications
Voltage
Current
•
4 amps
Frequency
•
50 Hz
For Research Use Only. Not for use in diagnostic procedures.
8 DISCOVERY ULTRA
DISCOVERY ULTRA independent slide staining system | IHC & ish
Ordering information
Product
Part number
DISCOVERY ULTRA
independent slide
preparation system
N750-DISU-FS 05870305001
DISCOVERY ULTRA
add-on module
N750-DISU-M 05870313001
Description
Part number
DISCOVERY ULTRA, full system
750-602
2482000
750-005
750-600
1697400
2505700
750-000
1632800
1418702
1650800
1196700
06376525001
Computer system
17" Flat screen monitor
Printer
Staining module
Accessory kit #1
Accessory kit #2
Power strip
E-Bar II bar code slide label system
Slide labelling system kit pack
Waste container and cart
Graduated carboy (20 L)
Bottle kit, DISCOVERY ULTRA
DISCOVERY ULTRA, staining module
750-600
1697400
2505700
753-000
1650800
1196700
06376525001
Staining Module
Accessory Kit #1
Accessory Kit #2
Power Strip
Waste container and cart
Graduated carboy (20 L)
Bottle kit, DISCOVERY ULTRA
DISCOVERY series accessories
Product
Part Number
Description
Dispenser rack
321-044 05263204001
Reagent dispenser storage rack — grey
Graduated carboy
1196700 05244676001
20 L receptacle for storage of diluted bulk solutions
Temperature verifier slides (10)
970-021 05424615001
Used for independent testing of slide heater function; 10 slides
Waste container
1468900 05249970001
Replacement waste container with spigot
Waste container cart
1465200 05249848001
Rolling cart used to hold waste container on DISCOVERY series systems
E-Bar II slide label system and accessories
Product
E-Bar II bar code slide
label system
Part Number
1632800 05250862001
Description
E-Bar electronic bar code labelling and printing system - printer ~100-240 v, 50/60
Hz.
Cable, parallel interface
Power cord (US/CAN)
Power cord (INTL)
Printer ribbon, E-Bar
Head cleaning pen
Insert sheet, quick setup
Insert sheet, ordering information
E-Bar mylar shields (5 shields/pkg)
Power supply
E-Bar label kit
1347100
1490500
1490100
1632900
1490000
1490400
1490300
1829000
1490200
1418702
E-Bar printer ribbon
1632900 05250889001
Prints 8,100 labels
Labels
1358501 05247829001
1 roll of 500 labels
E-Bar Label Kit
1418702 05248850001
5 rolls of 500 labels and 5 mylar shields. Printer ribbon not included
For Research Use Only. Not for use in diagnostic procedures.
www.ventana.com | www.roche.com 9
The products that appear on this page are IVD (for in vitro diagnostic use).
10 DISCOVERY XT automated slide staining system | IHC & ish
DISCOVERY XT
automated slide staining system
The VENTANA DISCOVERY XT system brings full automation,
reproducibility and productivity to immunohistochemistry (IHC), in situ
hybridisation (ISH) and microarray slide preparation and processing. Use the
flexible DISCOVERY XT platform to accelerate the discovery of new targets
and biomarkers, speed assay development and target validation and quickly
determine the toxicity of new drug candidates in the preclinical phase.
Flexibility
• Process IHC, ISH, TMA or DNA microarray samples
independently or simultaneously
• Develop protocols with flexible options to design
matrix experiments
Reproducibility
• Minimise experiment repeats with the automation of all
slide processing steps – from baking through staining
• Enhance slide-to-slide and run-to-run reproducibility with
ready-to-use, automation-optimised reagents
Productivity
• Automate all slide processing steps – from baking
through staining
• Develop assays for validation and process up to 30 matrix
experiments in a single run
• Process up to 60 IHC slides in seven hours, or up to 480
slides with additional modules
• Increase your throughput with rapid turnaround time
• Enhance your productivity with unattended overnight
slide processing
• Reduce experimental repeats with standardised slide handling
• Reduce antibody utilisation with optimised reaction kinetics
• Run up to eight VENTANA slide processing modules from a
single command centre
• Save time and reduce errors with optimised,
ready-to-use reagents
• Gain walk-away convenience and operational simplicity
with patented slide barcoding and protocol encryption
For Research Use Only. Not for use in diagnostic procedures.
www.ventana.com | www.roche.com 11
IHC & ish | DISCOVERY XT automated slide staining system
Specifications
General characteristics
Slide tray
•
1-30 slides with independent temperature control for each position
Capability
•
IHC, ISH, FISH, tissue microarray (TMA) and DNA microarray*
Reagent carousel
•
35 reagent positions
Slides
•
25 x 75 mm, 1 x 3 inches or 26 x 76 mm Superfrost Plus
Modularity
•
1 to 8 DISCOVERY XT and/or other VENTANA systems may be controlled from one control centre
Water quality
•
NCCLS Type II water or equivalent (referred to as deionised water)
Bulk reagents
•
Up to seven different bulk reagents in 3 to 6 litre on-board containers
Configurations
•
Floor mounted
Certifications
•
CSA and CE compliant (Research use only)
ThermoPad temperature range
•
37 °C to 100 °C ± 2.0 °C
Heat
•
Output 400 BTU/Hour idle, 1000 BTU/Hour running
Operating temperature
•
20 °C to 32 °C (68 °F to 90 °F). Note: The instrument may be
unable to maintain proper reaction temperature if laboratory
ambient temperature exceeds the specified temperature range.
Humidity
•
10% to 90%, non-condensing
Location
•
Flat, level surface. No direct sunlight or drafts. Remove from
sources of direct heat and moisture. Maximum altitude 1828m
(6000’) above sea level. For indoor use only. Do not position the
instrument so that it is difficult to remove the main plug from the
power outlet.
Environmental requirements
Physical characteristics
Size (Width x depth x height)
•
88.9 x 66.0 x 153.0 cm
Weight
•
175 kg
Clearances
•
Top 38.1 cm
Sides 10.2 cm
Rear 15.2 cm
DISCOVERY XT
Electrical requirements
Voltage
•
230 VAC ±10%
Current
•
4 Amps
Frequency
•
50 Hz.
*Ventana is not licensed under any patents owned by Oxford Gene Technology Limited or related companies
(“OGT”) and cannot pass any such license to its customers. A license under OGT’s patents may be necessary
to manufacture or use oligonucleotide arrays. To enquire about a license under OGT’s oligonucleotide array
patents, please contact [email protected]. For information about OGT visit www.ogt.co.uk.
For Research Use Only. Not for use in diagnostic procedures.
12 DISCOVERY XT automated slide staining system | IHC & ish
Ordering information
Product
Part Number
DISCOVERY XT
automatted slide
preparation system
750-DISXT-FS 05280621001
DISCOVERY XT add-on
module
750-DISXT-M 05280630001
Description
Part Number
DISCOVERY XT, full system
Computer system
Staining module
Accessory kit #1
Accessory kit#2
Power strip
Waste container and cart
Graduated carboy (20L)
Assay, bottle ship kit
750-012
750-701
1963500
1981600
322-001
1650800
1196700
1872600
DISCOVERY XT, staining module
750-700
1963500
1981600
753-000
1650800
1196700
Staining module
Accessory kit #1
Accessory kit #2
Power strip
Waste container and cart
Graduated carboy (20L)
DISCOVERY series accessories
Product
Part Number
Description
Dispenser rack
321-044 05263204001
Reagent dispenser storage rack — grey
Graduated carboy
1196700 05244676001
20 L receptacle for storage of diluted bulk solutions
Temperature verifier slides (10)
970-021 05424615001
Used for independent testing of slide heater function; 10 slides
Waste container
1468900 05249970001
Replacement waste container with spigot
Waste container cart
1465200 05249848001
Rolling cart used to hold waste container on DISCOVERY series systems
E-Bar II slide label system and accessories
Product
E-Bar II bar code slide
label system
Part Number
1632800 05250862001
Description
E-Bar electronic bar code labelling and printing system - printer ~100-240 v, 50/60
Hz.
Cable, parallel interface
Power cord (US/CAN)
Power cord (INTL)
Printer ribbon, E-Bar
Head cleaning pen
Insert sheet, quick setup
Insert sheet, ordering information
E-Bar mylar shields (5 shields/pkg)
Power supply
E-Bar label kit
1347100
1490500
1490100
1632900
1490000
1490400
1490300
1829000
1490200
1418702
E-Bar Printer Ribbon
1632900 05250889001
Prints 8,100 labels.
Labels
1358501 05247829001
1 roll of 500 labels.
E-Bar Label Kit
1418702 05248850001
5 rolls of 500 labels and 5 mylar shields. Printer ribbon not included.
For Research Use Only. Not for use in diagnostic procedures.
www.ventana.com | www.roche.com 13
IHC & ish | Detection Chemistries
Detection Chemistries
VENTANA DISCOVERY detection chemistries vary in sensitivity, giving you the flexibility to choose the detection that meets your research needs.
*Stained images are LMO2 on tonsil.
DAB
DABMap
OmniMap HRP
UltraMap HRP
DISCOVERY Amp HQ
Red
RedMap
UltraMap Red
DISCOVERY Amp HQ
Blue
BlueMap
UltraMap Blue
DISCOVERY Amp HQ
Low
High
Sensitivity
14 Detection Chemistries | IHC & ish
Multimer detection
Our innovative multimer technology consists of highly specific secondary
antibodies directly joined to powerful enzymes with long-arm linkers using
a proprietary controlled conjugation and purification process. The biotinfree design and robust chemistry provide clean background with enhanced
sensitivity and dynamic range, increasing the signal-to-noise ratio. The
compact size of the molecule enables diffusion through tissues, promoting
access to targeted binding sites. The conjugate design preserves the highly
specific activity of the enzyme.
Secondary antibody
Multimer molecule
Linker
Enzyme
The long arm linkers attach enzymes directly to the
secondary antibodies. The smaller multimer molecule
minimises steric hindrance and improves sensitivity while
biotin-free chemistry eliminates endogenous biotin staining.
www.ventana.com | www.roche.com 15
IHC & ish | Detection Chemistries
UltraMap Multimer detection kits
UltraMap DAB anti-Ms
Catalogue Number
Status
Quantity
Composed of
760-152 05266572001
For Research Use Only. Not for use in diagnostic procedures.
125 tests
UltraMap anti-MS HRP
05269695001
ChromoMap DAB
05266645001
Hif1 apha (mouse monoclonal) on mouse xenograft using UltraMap DAB anti-Ms
Description
The UltraMap DAB anti-Mouse is a biotin-free detection system that uses an HRP-multimer for the detection of an antibody raised in mouse. The
brown staining is obtained by the enzymatic reaction between HRP and DAB contained in the kit. This detection kit can be used for IHC.
Note: This product may also be used for ISH on the DISCOVERY ULTRA instrument.
UltraMap DAB anti-Rb
Catalogue Number
Status
Quantity
Composed of
760-151 05266564001
For Research Use Only. Not for use in diagnostic procedures.
125 tests
UltraMap anti-Rb HRP
05269717001
ChromoMap DAB
05266645001
pERk (rabbit polyclonal) on human skin using UltraMap DAB anti-Rb
Description
The UltraMap DAB anti-Rabbit is a biotin-free detection system that uses an HRP-multimer for the detection of an antibody raised in rabbit. The
brown staining is obtained by the enzymatic reaction between HRP and DAB/H2O2 contained in the kit. This detection kit can be used for IHC.
Note: This product may also be used for ISH on the DISCOVERY ULTRA instrument.
UltraMap DAB anti-Rat
Catalogue Number
Status
Quantity
Composed of
760-160 05266653001
For Research Use Only. Not for use in diagnostic procedures.
125 tests
UltraMap anti-Rat HRP
05891884001
ChromoMap DAB
05266645001
F4/80 on mouse spleen using UltraMap DAB anti-Rat
Description
The UltraMap DAB anti-Rat is a biotin-free detection system that uses an HRP-multimer for the detection of an antibody raised in rat. The brown
staining is obtained by the enzymatic reaction between HRP and DAB/ H2O2 contained in the kit. This detection kit can be used for IHC.
Note: This product may also be used for ISH on the DISCOVERY ULTRA instrument.
16 Detection Chemistries | IHC & ish
UltraMap Red anti-Ms
Catalogue Number
Status
Quantity
Composed of
760-154 05266602001
For Research Use Only. Not for use in diagnostic procedures.
125 tests
UltraMap anti-Ms Alk- Phos
05269687001
ChromoMap Red
05266653001
pKCß2 on human tonsil (mouse, clone PK-B26) with UltraMapRed anti-Ms and pHH3 (Rabbit
polyclonal) withUltraMap DAB anti-Rb
Description
The UltraMap Red anti-Mouse is a biotin-free detection system that uses an AP-multimer for the detection of an antibody raised in mouse. The
red staining is obtained by the reaction between AP and Naphtol/Fast Red contained in the kit. This detection kit can be used for IHC and ISH.
UltraMap Red anti-Rb
Catalogue Number
Status
Quantity
Composed of
760-153 05266599001
For Research Use Only. Not for use in diagnostic procedures.
125 tests
UltraMap anti-Rb Alk- Phos
05269709001
ChromoMap Red
05266653001
p27 KIP1 (rabbit polyclonal) on human colon using UltraMap Red anti-Rb
Description
The UltraMap Red anti-Rabbit is a biotin-free detection system that uses an AP-multimer for the detection of an antibody raised in rabbit. The
red staining is obtained by the reaction between AP and Naphtol/Fast Red contained in the kit. This detection kit can be used for IHC and ISH.
UltraMap Blue anti-Ms
Catalogue Number
Status
Quantity
Composed of
760-156 05266637001
For Research Use Only. Not for use in diagnostic procedures.
125 tests
UltraMap anti-Ms Alk- Phos
05269687001
ChromoMap Blue
05266661001
Description
The UltraMap Blue anti-Mouse is a biotin-free detection system that uses an AP-multimer for the detection of an antibody raised in mouse. The blue
staining is obtained by the reaction between AP and NBT/BCIP contained in the kit. This detection kit can be used for IHC and ISH.
www.ventana.com | www.roche.com 17
IHC & ish | Detection Chemistries
UltraMap Blue anti-Rb
Catalogue Number
Status
Quantity
Composed of
760-155 05266629001
For Research Use Only. Not for use in diagnostic procedures.
125 tests
UltraMap anti-Rb Alk- Phos
05269709001
ChromoMap Blue
05266661001
VEGF anti-sense probe on mouse kidney using UltraMap Blue anti-Rb
Description
The UltraMap Blue anti-Rabbit is a biotin-free detection system that uses an AP-multimer for the detection of an antibody raised in rabbit. The blue
staining is obtained by the reaction between AP and NBT/BCIP contained in the kit. This detection kit can be used for IHC and ISH.
OmniMap Peroxidase Multimer detection kits
OmniMap DAB anti-Mouse (Ms)
Catalogue Number
Status
Quantity
Composed of
760-150 05266556001
For Research Use Only. Not for use in diagnostic procedures.
125 tests
OmniMap anti-Ms HRP
ChromoMap DAB
05269652001
05266645001
Hif1 alpha (mouse monoclonal) on mouse xenograft using OmniMap DAB anti-Ms
Description
The OmniMap DAB anti-Mouse is a biotin-free detection system that uses an HRP-multimer for the detection of an antibody raised in mouse. The
brown staining is obtained by the enzymatic reaction between HRP and DAB/H2O2 contained in the kit. This detection kit can be used for IHC.
Note: This product may also be used for ISH on the enzymatic DISCOVERY ULTRA instrument.
OmniMap DAB anti-Rabbit (Rb)
Catalogue Number
Status
Quantity
Composed of
760-149 05266548001
For Research Use Only. Not for use in diagnostic procedures.
125 tests
OmniMap anti-Rb HRP
05269679001
ChromoMap DAB
05266645001
pERK (rabbit polyclonal) on human skin using OmniMap DAB anti-Rb
Description
The OmniMap DAB anti-Rabbit is a biotin-free detection system that uses an HRP-multimer for the detection of an antibody raised in rabbit. The
brown staining is obtained by the enzymatic reaction between HRP and DAB/ H2O2 contained in the kit. This detection kit can be used for IHC.
Note: This product may also be used for ISH on the DISCOVERY ULTRA instrument.
18 Detection Chemistries | IHC & ish
OmniMap DAB anti-Rat
Catalogue Number
Status
Quantity
Composed of
760-157 06525709001
For Research Use Only. Not for use in diagnostic procedures.
125 tests
OmniMap anti-Rat HRP
05269679001
ChromoMap Blue
05266661001
F4/80 in mouse spleen using OmniMap DAB anti-Rt
Description
The OmniMap anti-Rat is a biotin-free detection system that uses an HRP multimer for the detection of an antibody raised in rat. The brown staining
is obtained by the enzymatic reaction between HRP and DAB/H2O2 contained in the kit. This detection can be used for IHC.
Note: This product may also be used for ISH on the DISCOVERY ULTRA instrument.
DISCOVERY detection kits are composed of a conjugate and a chromogen. The following lists the conjugates and compatible
chromogen(s). Items can be purchased separately but must be used together to achieve desired staining results.
Conjugate
Compatible chromogen
OmniMap anti-Ms HRP
760-4310 05269652001
ChromoMap DAB
760-159 05266645001
OmniMap anti-Rb HRP
760-4311 05269679001
ChromoMap DAB
760-159 05266645001
OmniMap anti-Rat HRP
760-4457 05891892001
ChromoMap DAB
760-159 05266645001
UltraMap anti-Ms HRP
760-4313 05269695001
ChromoMap DAB
760-159 05266645001
UltraMap anti-Rb HRP
760-4315 05269717001
ChromoMap DAB
760-159 05266645001
UltraMap anti-Rat HRP
760-4456 05891884001
ChromoMap DAB
760-159 05266645001
UltraMap anti-Goat HRP
760-4648 06607241001
ChromoMap DAB
760-159 05266645001
UltraMap anti-Ms Alk-Phos
760-4312 05269687001
ChromoMap Red or ChromoMap Blue
760-160 or 760-161 05266653001 or
05266661001
UltraMap anti-Rb Alk-Phos
760-4314 05269709001
ChromoMap Red or ChromoMap Blue
760-160 or 760-161 05266653001 or
05266661001
UltraMap Goat anti-Rb and
Goat anti-Ms Alk-Phos Cocktail*
760-4498 05860776001
ChromoMap Red or ChromoMap Blue
760-160 or 760-161 05266653001 or
05266661001
* UltraMap goat anti-Rb and goat anti-Ms Alk-Phos Cocktail contains goat anti-Rabbit IgG and Goat anti-Mouse IgG. This is an IgM free product.
www.ventana.com | www.roche.com 19
IHC & ish | Detection Chemistries
Streptavidin-biotin detection kits
The VENTANA streptavidin technology allows for the sensitive and specific
detection of the cellular target. The VENTANA DABMap Detection Kit
incorporates conjugated streptavidin HRP technology, while VENTANA
RedMap and VENTANA BlueMap kits incorporate conjugated streptavidin
alkaline phosphatase technology. All three detection kits allow for your choice
of biotinylated secondary antibody to combine with either DAB, red (Naphthol/
Fast Red) or blue (NBT/BCIP) chromogen. A biotinylated goat anti-rabbit or a
universal anti-rabbit and anti-mouse secondary is also available for use with
these kits.
DABMap Kit (streptavidin horseradish peroxidase detection kit)
Catalogue Number
Status
Quantity
760-124 05266360001
For Research Use Only. Not for use in diagnostic procedures.
250 tests
pEGFR (phospho EGFR) on xenograft using DABMap
Description
The DABMap kit relies on the interaction between the HRP/SA complex and a biotinylated antibody and the subsequent reaction with DAB to
produce a brown staining. This detection kit can be used for IHC and ISH.
RedMap Kit (streptavidin alkaline phosphatase detection kit)
Catalogue Number
Status
Quantity
760-120 05266351001
For Research Use Only. Not for use in diagnostic procedures.
250 tests
Muscle Actin using RedMap and Keratin using DAB Map on human stomach
Description
The RedMap kit relies on the interaction between the AP/SA complex and a biotinylated antibody and the subsequent reaction with Naphtol/Fast
Red to produce a red staining. This detection kit can be used for IHC and ISH.
20 Detection Chemistries | IHC & ish
BlueMap Kit (streptavidin alkaline phosphatase detection kit)
Catalogue Number
Status
Quantity
760-120 05266327001
For Research Use Only. Not for use in diagnostic procedures.
125 tests
Delta 1 anti-sense probe on chicken embryo using BlueMap Kit
Description
The BlueMap kit relies on the interaction between the AP/SA complex and a biotinylated antibody and the subsequent reaction with NBT/BCIP to
produce a blue staining. This detection kit can be used for IHC and ISH.
Secondary antibodies for use with avidin biotin detection kits
DISCOVERY Biotinylated Rabbit Secondary Antibody
Catalogue Number
Status
Quantity
760-4507 06135234001
For Research Use Only. Not for use in diagnostic procedures.
250 tests
Description
Biotinylated goat anti-rabbit lgG in a protein block for use with detection kits.
DISCOVERY Universal Secondary Antibody
Catalogue Number
Status
Quantity
760-4205 05268877001
For Research Use Only. Not for use in diagnostic procedures.
250 tests
Description
Biotinylated goat anti-rabbit lgG cocktailed with goat anti-mouse in a protein block for use with detection kits.
www.ventana.com | www.roche.com 21
IHC & ish | Detection Chemistries
Discovery Amp HQ
VENTANA DISCOVERY Amp HQ is a novel detection kit specifically
intended for low-expressing gene targets or low-abundance proteins. This
proprietary amplification method deposits the VENTANA HQ hapten directly
at a successfully identified target site, creating a crisp strong signal. The HQ
hapten is not endogenously occurring within human, mouse or rat tissue, thus
dramatically reducing any cross-reactivity and background staining.
DISCOVERY Amp HQ Kit
Catalogue Number
Status
Quantity
Components
760-052 06472320001
For Research Use Only. Not for use in diagnostic procedures.
50 tests
Amplification HQ, PO Inhibitor, H2O2
Description
Enzyme-based detection amplification kit utilising our proprietary HQ hapten technology. The DISCOVERY Amp HQ kit, in conjunction with 1) an
anti-HQ Multimer, 2) an OmniMap or UltraMap HRP Multimer and 3) a chromogenic detection kit, enables the enhancement of the chromogenic
signal in standard immunohistochemistry (IHC) and in situ hybridisation (ISH) protocols.
DISCOVERY anti-HQ Alk-Phos Multimer
Catalogue Number
Status
Quantity
760-4521 06472311001
For Research Use Only. Not for use in diagnostic procedures.
50 tests
Description
Mouse anti-HQ Alkaline Phosphatase Multimer provides signal amplification without loss of resolution. In conjunction with 1) the DISCOVERY Amp
HQ Kit, 2) an OmniMap or UltraMap HRP Multimer and 3) a chromogenic detection kit, the DISCOVERY anti-HQ AP Multimer provides the ability to
enhance the chromogenic signal in standard immunohistochemistry (IHC) and in situ hybridisation (ISH) protocols.
DISCOVERY anti-HQ HRP Multimer
Catalogue Number
Status
Quantity
760-4602 06442544001
For Research Use Only. Not for use in diagnostic procedures.
50 tests
Description
Mouse anti-HQ Horseradish Peroxidase (HRP) Multimer provides signal amplification without loss of resolution. In conjunction with 1) the
DISCOVERY Amp HQ kit, 2) an OmniMap or UltraMap HRP Multimer and 3) a chromogenic detection kit, DISCOVERY anti-HQ HRP Multimer
provides the ability to enhance the chromogenic signal in standard immunohistochemistry (IHC) and in situ hybridisation (ISH) protocols.
22 Detection Chemistries | IHC & ish
ChromoMap substrate
ENZ
ENZ
ENZ
ENZ
é 5.
Mouse anti-HQ antibody conjugated
to enzyme binds to HQ
é 4.
Tyramide molecule conjugated to
novel, proprietary HQ hapten reacts
with HRP and H2O2 at target site,
covalently bonding tyramide to tissue
Enzyme (AP or HRP)
ENZ
HQ
ENZ
Mouse anti-HQ-AP or
Mouse anti-HQ-HRP
HQ
HQ
+H2O2
HRP
HRP
é 3.
OmniMap anti-species multimer
molecule conjugated to HRP binds
to primary antibody
é 2.
Peroxidase inhibitor is applied to
reduce endogenous peroxidase activity
é 1.
Primary antibody binds to target
antigen in tissue
HRP
OmniMap HRP
Primary antibody
Tissue
www.ventana.com | www.roche.com 23
IHC & ish | Detection Chemistries
Quantum dot detection
VENTANA Quantum dots (QD) bring nanotechnology and life sciences
together to create novel applications in fluorescent labelling. Available in
wavelengths ranging from ultra-violet to near infra-red, Qdot Nanocrystals
(Life Technologies, Corp.) allow the visualisation of multiplexed biomarkers.
In histochemistry, entire pathways may be profiled for biomarker expression
using quantum dot technology while preserving the correct anatomical
context. Applications may be developed for immunohistochemistry assays.
QD Map fluorescent detection kits are designed for sensitive stable antigen
localisation in cytological preparations, frozen sections or formalin-fixed
paraffin-embedded tissue sections.
QD Map 605 SA-25
Catalogue Number
Status
Quantity
May be used with
760-4176 05268745001
For Research Use Only. Not for use in diagnostic procedures.
25 tests
QD DAPI
05268826001
QD Link
05266483001
Ig Kappa (#760-2514) shown in green using QD Map 605 SA-25 and Ig Lambda (#760-2515)
shown in red using QD Map 655 SA-25 on a human tonsil. Nuclei stained blue using QD
DAPI counterstain.
Description
The QD Map 605 SA-25 kit consists of a quantum dot 605/streptavidin complex used for the fluorescent detection (emission wavelength: 605 nm)
of a biotinylated antibody. This kit is dedicated to IHC applications on Discovery series systems.
QD Map 655 SA-25
Catalogue Number
Status
Quantity
May be used with
760-4176 05268753001
For Research Use Only. Not for use in diagnostic procedures.
25 tests
QD DAPI
05268826001
QD Link
05268826001
HER-2 shown in magenta using QD Map 655 SA-25 and p53 shown in blue using QD Map 605 SA25 on human breast carcinoma
Description
The QD Map 655 SA-25 kit consists of a Quantum Dot 655/streptavidin complex used for the fluorescent detection (emission wavelength: 655
nm) of a biotinylated antibody. This kit is dedicated to IHC applications on DISCOVERY series systems.
24 Primary Antibodies | IHC & ish
Primary Antibodies
Clone
Species
Tests/
Dispenser
A-1-Antichymotrypsin (ACT)
Polyclonal
Rabbit
50
760-2604 05267196001
A-1-Antitrypsin (AAT)
Polyclonal
Rabbit
50
760-2605 05267200001
ACTH
Polyclonal
Rabbit
50
760-2708 05268176001
Actin, Muscle
HUC1-1
Mouse
50
760-2502 05266882001
Actin, Muscle Specific
HHF35
Mouse
50
760-2601 05267161001
Actin, Smooth Muscle
1A4
Mouse
50
760-2833 05268303001
ALK01
Mouse
50
800-2918 05278783001
Polyclonal
Rabbit
50
760-2603 05267188001
Androgen Receptor
SP107
Rabbit
50
760-4605 06523838001
Annexin A1
MRQ-3
Mouse
50
760-4435 05973945001
Basal Cell Cocktail, VENTANA
34βE12 + 4A4
Mouse Cocktail
50
790-4536 06364497001
Basal Cell Cocktail, VENTANA
Antibody
ALK1
Alpha-1-Fetoprotein (AFP)
Ventana P/N
Roche P/N
34βE12 + 4A4
Mouse Cocktail
250
790-1010 06419445001
BCA-225
Cu-18
Mouse
50
760-2607 05267226001
bcl-2
SP66
Rabbit
50
790-4604 06446329001
bcl-2
124
Mouse
50
790-4464 05986826001
bcl-6
GI191E/A8
Mouse
50
760-4241 05269008001
14
Mouse
50
760-4242 05269016001
Beta-Catenin
BG8, Lewis
F3
Mouse
50
760-4450 05973767001
SP92
Rabbit
50
760-4593 06433308001
c-KIT (CD117), PATHWAY
9.7
Rabbit
50
790-2951 05278317001
c-MET (Total), CONFIRM
SP44
Rabbit
50
790-4430 05571219001
c-MYC
Y69
Rabbit
50
790-4628 06504612001
C3d
Polyclonal
Rabbit
50
760-4522 06419143001
C4d
Polyclonal
Rabbit
50
760-4436 05973937001
CA 19-9
121SLE
Mouse
50
760-2609 05267242001
CA 125
OC125
Mouse
50
760-2610 05267269001
Calcitonin
Polyclonal
Rabbit
50
760-2611 05267277001
Calcitonin
SP17
Rabbit
50
760-4705 06586554001
Caldesmon
E89
Rabbit
50
760-4375 05463459001
Calponin-1
EP798Y
Rabbit
50
760-4376 05435684001
y
BOB.1
Calretinin
SP65
Rabbit
50
790-4467 05992184001
CD1a
EP3622
Rabbit
50
760-4525 06419160001
CD2
MRQ-11
Mouse
50
760-4377 05463467001
CD3
2GV6
Rabbit
50
790-4341 05278422001
CD4
SP35
Rabbit
50
790-4423 05552737001
CD5
SP19
Rabbit
50
790-4451 05929903001
CD7
SP94
Rabbit
50
790-4558 06537847001
CD8
SP57
Rabbit
50
790-4460 05937248001
The products that appear on this page are IVD (for in vitro diagnostic use).
www.ventana.com | www.roche.com 25
IHC & ish | Primary Antibodies
Antibody
CD10, VENTANA
Species
Tests/
Dispenser
Ventana P/N
Roche P/N
SP67
Rabbit
50
790-4506 05857856001
CD14
EPR3653
Rabbit
50
760-4523 06419151001
CD15
MMA
Mouse
50
760-2504 05266904001
CD20
L26
Mouse
50
760-2531 05267099001
CD21
EP3093
Rabbit
50
760-4438 05973902001
CD21
2G9
Mouse
50
760-4245 05269059001
CD22
SP104
Rabbit
50
790-4588 06391117001
CD23
SP23
Rabbit
50
790-4408 05479258001
CD25
4C9
Mouse
50
760-4439 05973899001
CD30
Ber-H2
Mouse
50
790-2926 05278201001
CD31
JC70
Mouse
50
760-4378 05463475001
CD34
QBEnd/10
Mouse
50
760-2927 05278210001
CD43
L60
Mouse
50
760-2511 05266980001
CD44
SP37
Rabbit
50
790-4537 06364985001
CD45 (LCA)
RP2/18
Mouse
50
760-2505 05266912001
CD45 (LCA)
2B11 & PD7/26
Mouse
50
760-4279 05269423001
MB1
Mouse
50
760-2624 05267340001
CD45RO
UCHL-1
Mouse
50
790-2930 05278244001
CD56
MRQ-42
Rabbit
50
760-4596 06433359001
CD57
NK-1
Mouse
50
760-2626 05267366001
CD61
2f2
Mouse
50
760-4249 05269091001
CD63
NKI/C3
Mouse
50
760-4379 05463483001
CD68
KP-1
Mouse
50
790-2931 05278252001
CD71
MRQ-48
Mouse
50
760-4589 06433162001
CD79a
SP18
Rabbit
50
790-4432 05640296001
CD99
O13
Mouse
50
790-4452 05913594001
CD45R
CD138/syndecan-1
B-A38
Mouse
50
760-4248 05269083001
CD163
MRQ-26
Mouse
50
760-4437 05973929001
CDX-2
EPR2764Y
Rabbit
50
760-4380 05463491001
CEA31
Mouse
50
760-4594 06433316001
CEA
Chromogranin A
LK2H10
Mouse
50
760-2519 05267056001
8B1.2, 1G5.2 & 2D4.2
Mouse
50
760-4703 06597190001
CIV22
Mouse
50
760-2632 05267439001
COX-2 (Cyclooxygenase 2)
SP21
Rabbit
50
760-4254 05269148001
Cyclin D1, VENTANA
SP4-R
Rabbit
50
790-4508 05862949001
AE1
Mouse
50
760-2521 05267064001
CMV Blend
Collagen Type IV
Cytokeratin
Cytokeratin
AE3
Mouse
50
790-2909 05278040001
CAM 5.2
Mouse
50
790-4555 06478425001
34βE12
Mouse
50
790-4373 05479266001
Cytokeratin (Pan)
AE1/AE3 & PCK26
Mouse
50
760-2595 05267145001
Cytokeratin (Pan)
AE1/AE3 & PCK26
Mouse
250
760-2135 05266840001
Cytokeratin (CAM5.2)
Cytokeratin (HMW)
The products that appear on this page are IVD (for in vitro diagnostic use).
26 Clone
Primary Antibodies | IHC & ish
Antibody
Clone
Species
Tests/
Dispenser
Ventana P/N
Roche P/N
Cytokeratin 5/6
D5/16B4
Mouse
50
06478441001
Cytokeratin 7
SP52
Rabbit
50
790-4462 05986818001
Cytokeratin 8
35betaH11
Mouse
50
760-2637 05267471001
B22.1 & B23.1
Mouse
50
760-4344 05269776001
Cytokeratin 8 & 18
Cytokeratin 10
SP99
Rabbit
50
790-4562 06425135001
Cytokeratin 14
LL002
Mouse
50
760-4251 05269113001
Cytokeratin 17
SP95
Rabbit
50
790-4560 06373658001
Cytokeratin 19
A53-B/A2.26
Mouse
50
760-4281 05269440001
Cytokeratin 20
SP33
Rabbit
50
790-4431 05587760001
DE-R-11
Mouse
50
760-2513 05267005001
Desmin
DOG1
SP31
Rabbit
50
760-4590 06433189001
E-Cadherin, VENTANA
36
Mouse
50
790-4497 05905290001
E-Cadherin, VENTANA
EP700Y
Rabbit
50
760-4440 05973872001
Ep-CAM/Epithelial Specific Antigen
Ber-EP4
Mouse
50
760-4383 05435676001
Epithelial Growth Factor Receptor (EGFR)
3C6
Mouse
50
790-2988 05278341001
Epithelial Growth Factor Receptor (EGFR)
5B7
Rabbit
50
790-4347 05278457001
Epithelial Membrane Antigen (EMA)
E29
Mouse
50
790-4463 05878900001
Epithelial Related Antigen
MOC-31
Mouse
50
790-4561 06374409001
ERG
EPR3864
Rabbit
50
790-4576 06478450001
SP1
Rabbit
50
790-4324 05278406001
Estrogen Receptor (ER)
Estrogen Receptor (ER)
SP1
Rabbit
250
790-4325 05278414001
Polyclonal
Rabbit
50
760-2642 05267528001
Factor XIIIa
AC-1A1
Mouse
50
760-4384 05435692001
Factor XIIIa
EP3372
Rabbit
50
760-4441 05922470001
55k-2
Mouse
50
760-2702 05268117001
Polyclonal
Rabbit
50
760-2710 05268192001
Factor VIII-R Ag
Fascin
FSH (Follicle Stimulating Hormone)
Galectin-3
9C4
Mouse
50
760-4256 05269164001
Polyclonal
Rabbit
50
760-2643 05267536001
GCDFP-15
EP1582Y
Rabbit
50
760-4386 05463530001
Glial Fibrillary Acidic Protein (GFAP)
EP672Y
Rabbit
50
760-4345 05269784001
Glucagon
Polyclonal
Rabbit
50
760-2644 05267544001
GLUT1
Polyclonal
Rabbit
50
760-4526 06419178001
GA-R2
Mouse
50
760-4257 05269172001
Gastrin
Glycophorin A
Glypican-3
1G12
Mouse
50
760-4442 05973864001
Glypican-3
GC33
Mouse
50
790-4564 06483186001
Granzyme B
Polyclonal
Rabbit
50
760-4283 05269466001
Growth Hormone (GH)
Polyclonal
Rabbit
50
760-2804 05268257001
hCG (Human Chorionic Gonadotropin)
Polyclonal
Rabbit
50
760-2650 05267617001
SP48
Rabbit
50
790-4374 05926092001
Helicobacter Pylori, VENTANA
Helicobacter Pylori, VENTANA
Hepatocyte Specific Antigen (HSA)
HER-2/neu, VENTANA
SP48
Rabbit
250
790-1009 05926084001
OCH1E5
Mouse
50
760-2350 05269792001
4B5
Rabbit
50
790-2991 05278368001
The products that appear on this page are IVD (for in vitro diagnostic use).
www.ventana.com | www.roche.com 27
IHC & ish | Primary Antibodies
Clone
Species
Tests/
Dispenser
Ventana P/N
Roche P/N
4B5
Rabbit
50
790-4493 05999570001
Herpes Simplex Virus I (HSV I)
Polyclonal
Rabbit
50
760-4261 05269237001
Herpes Simplex Virus II (HSV II)
Polyclonal
Rabbit
50
760-4262 05269245001
MRQ-49
Mouse
50
760-4597 06433375001
Antibody
HER-2/neu, VENTANA
HGAL
HHV-8 (Human Herpes Virus Type 8)
13B10
Mouse
50
760-4260 05269229001
Human Placental Lactogen (hPL)
Polyclonal
Rabbit
50
760-4443 05973830001
IgA (Immunoglobulin A)
Polyclonal
Rabbit
50
760-2652 05267625001
IgD (Immunoglobulin D)
Polyclonal
Rabbit
50
760-4444 05973821001
IgG (Immunoglobulin G)
Polyclonal
Rabbit
50
760-2653 05267633001
MRQ-44
Mouse
50
760-4614 06523854001
IgG4
IgM (Immunoglobulin M)
Inhibin, alpha
INI-1
Insulin
Insulin Growth Factor-1 Receptor (IGF-1R)
Rabbit
50
760-2654 05267641001
R1
Mouse
50
760-2834 05268311001
MRQ-27
Mouse
50
760-4615 06523862001
Polyclonal
Rabbit
50
760-2655 05267650001
G11
Rabbit
50
790-4346 05278449001
Kappa
Polyclonal
Rabbit
50
760-2514 05267013001
Ki-67
30-9
Rabbit
50
790-4286 05278384001
Ksp-Cadherin
MRQ-33
Mouse
50
760-4387 05463548001
Lambda
Polyclonal
Rabbit
50
760-2515 05267021001
LH (Luteinizing Hormone)
Polyclonal
Rabbit
50
760-2802 05268222001
LMO2
1A9-1
Mouse
50
790-4368 05479274001
LMO2
SP51
Rabbit
50
760-4704 06586546001
Polyclonal
Rabbit
50
760-2656 05267668001
HAM-56
Mouse
50
760-2657 05267676001
Mammaglobin
31A5
Rabbit
50
760-4263 05269253001
MART-1/melan A
A103
Mouse
50
790-2990 05278350001
Lysozyme
Macrophage
Melanoma Associated Antigen
KBA.62
Mouse
50
760-4527 06419186001
Melanoma Associated Antigen
PNL2
Mouse
50
760-4528 06419194001
HMB45+A103+T311
Cocktail
50
790-4677 06527787001
Melanosome (HMB45)
HMB45
Mouse
50
790-4366 05479282001
Mesothelial Cell
HBME-1
Mouse
50
760-4445 05973813001
C5/D5
Mouse
50
790-4367 05549175001
MLH-1
M1
Mouse
50
790-4535 06472966001
MSH2
G219-1129
Mouse
50
760-4265 05269270001
MSH6
44
Mouse
50
790-4455 05929911001
MUC1
H23
Mouse
50
790-4574 06316514001
Melanoma Triple Cocktail
MITF
MUC2
MRQ-18
Mouse
50
760-4388 05463556001
MUC5AC
MRQ-19
Mouse
50
760-4389 05463564001
MUC6
MRQ-20
Mouse
50
760-4390 05463572001
MUM1
Myeloperoxidase (MPO)
Myogenin
The products that appear on this page are IVD (for in vitro diagnostic use).
28 Polyclonal
MRQ-43
Rabbit
50
760-4529 06419208001
Polyclonal
Rabbit
50
760-2659 05267692001
F5D
Mouse
50
760-2832 05268290001
Primary Antibodies | IHC & ish
Clone
Species
Tests/
Dispenser
Ventana P/N
Roche P/N
Polyclonal
Rabbit
50
760-2832 05267706001
Myosin, Smooth Muscle
SMMS-1
Mouse
50
760-2704 05268133001
Napsin A
Polyclonal
Rabbit
50
760-4446 05973805001
Negative Control Mouse Ig
MOPC21
Mouse
50
760-2014 05266670001
Negative Control Rabbit Ig
Polyclonal
Rabbit
50
760-1029 05266238001
MRQ-21
Mouse
50
760-4391 05463599001
2F11
Mouse
50
760-2661 05267714001
Antibody
Myoglobin
Nerve Growth Factor Receptor (NGFR)
Neurofilament
Oct-2
MRQ-2
Mouse
50
760-4447 05973791001
Oct-4
MRQ-10
Mouse
50
760-4392 05463602001
DCS-60.2
Mouse
50
760-4453 05973961001
p21WAF1
p27
SX53G8
Mouse
50
760-4268 05269300001
p53
Bp53-11
Mouse
50
760-2542 05267102001
p53
DO-7
Mouse
50
800-2912 05278775001
p57
Kp10
Mouse
50
760-4617 06523897001
kip1
kip2
p63, VENTANA
p120 catenin, VENTANA
Parathyroid Hormone (PTH)
4A4
Mouse
50
790-4509 05867061001
98
Mouse
50
790-4517 05867088001
MRQ-31
Mouse
50
760-4532 06419224001
PAX-5
SP34
Rabbit
50
790-4420 05552729001
PAX8
MRQ-50
Mouse
50
760-4618 06523927001
Perforin
MRQ-23
Mouse
50
760-4394 05463637001
PGP 9.5 (Protein Gene Product 9.5)
Polyclonal
Rabbit
50
760-4434 05973953001
Phosphohistone-H3 (PHH3)
Polyclonal
Rabbit
50
760-4591 06433405001
NB10
Mouse
50
760-2664 05267757001
PLAP (Placental Alkaline Phosphatase)
PMS2
Podoplanin
Progesterone Receptor (PR)
EPR3947
Rabbit
50
760-4531 06419216001
D2-40
Mouse
50
760-4395 05463645001
1E2
Rabbit
50
790-2223 05277990001
Progesterone Receptor (PR)
1E2
Rabbit
250
790-4296 05278392001
Programmed Death-1 (PD-1)
MRQ-22
Mouse
50
760-4448 05973783001
Prolactin
Polyclonal
Rabbit
50
760-2803 05268249001
Prostate Specific Antigen (PSA)
Polyclonal
Rabbit
50
760-2506 05266939001
PSAP (Placental Alkaline Phosphatase)
PASE/4LJ
Mouse
50
760-4272 05269342001
Renal Cell Carcinoma (RCC)
PN-15
Mouse
50
760-4273 05269369001
S100
4C4.9
Mouse
50
790-2914 05278104001
S100
Polyclonal
Rabbit
50
760-2523 05267072001
S100P
16/f5
Mouse
50
760-4620 06523935001
Smoothelin
R4A
Mouse
50
760-4592 06433278001
Somatostatin
Polyclonal
Rabbit
50
760-2667 05267781001
SP76
Rabbit
50
760-4621 06523943001
RBC2/3D5
Mouse
50
760-4274 05269377001
SV40 (Simian Virus-40)
MRQ-4
Mouse
50
760-4449 05973775001
Synaptophysin
MRQ-40
Rabbit
50
760-4595 06433324001
T-bet
MRQ-46
Rabbit
50
760-4598 06433391001
SOX-2
Spectrin
The products that appear on this page are IVD (for in vitro diagnostic use).
www.ventana.com | www.roche.com 29
IHC & ish | Primary Antibodies
Clone
Species
Tests/
Dispenser
Ventana P/N
Roche P/N
B72.3
Mouse
50
760-2669 05267803001
Polyclonal
Rabbit
50
760-2670 05267811001
TFE3
MRQ-37
Rabbit
50
760-4622 06523951001
Thymidine Phosphorylase (TP)
P-GF.44C
Mouse
50
790-4454 05976502001
Thyroglobulin
2H11+6E1
Mouse
50
760-2671 05267820001
Thyroid Transcription Factor-1 (TTF-1)
8G7G3/1
Mouse
50
790-4398 05479312001
JS5B4
Rabbit
50
790-4371 05479339001
Antibody
TAG-72
TdT (Terminal Deoxynucleotidyl Transferase)
Topoisomerase IIa
TRAcP (Tartrate-Resistant Acid Phosphatase)
9C5
Mouse
50
760-4275 05269385001
Tryptase
G3
Mouse
50
760-4276 05269393001
8G7G3/1
Rabbit
50
760-2709 05268184001
Tyrosinase
T311
Mouse
50
790-4365 05479347001
Uroplakin III
SP73
Rabbit
50
760-4533 06419232001
Villin
CWWB1
Mouse
50
760-4277 05269407001
Vimentin
Vim 3B4
Mouse
50
760-2512 05266998001
TSH (Thyroid Stimulating Hormone)
Vimentin
V9
Mouse
50
790-2917 05278139001
WT1
6F-H2
Mouse
50
760-4397 05435706001
ZAP-70
2F3.2
Mouse
50
760-4278 05269415001
Clone
Species
Tests/
Dispenser
Ventana P/N
Roche P/N
FITC Albumin
Polyclonal
Goat
50
760-2699 05268087001
FITC C1q
Polyclonal
Goat
50
760-2688 05267994001
FITC C3
Polyclonal
Goat
50
760-2686 05267978001
FITC C4
Polyclonal
Sheep
50
760-2687 05267986001
FITC Fibrinogen
Polyclonal
Goat
50
760-2685 05267960001
FITC IgA (Immunoglobulin A)
Polyclonal
Goat
50
760-2681 05267927001
FITC IgG ( (Immunoglobulin G)
Polyclonal
Goat
50
760-2680 05267919001
FITC IgM (Immunoglobulin M)
Polyclonal
Goat
50
760-2682 05267935001
FITC Kappa
Polyclonal
Goat
50
760-2683 05267943001
FITC Lambda
Polyclonal
Goat
50
760-2684 05267951001
The products that appear in this table are IVD (for in vitro diagnostic use).
FITC Antibodies
Antibody
The products that appear in this table are IVD (for in vitro diagnostic use).
RUO antibodies
30 Antibody
Clone
Species
Tests/
Dispenser
Ventana P/N
Roche P/N
Prostate Specific Antigen (PSA)
ER-PR8
Mouse
50
760-4271 05269334001
Molecular Probes | IHC & ish
Molecular Probes
Molecular Probe
Chromosome 3 DIG Probe
Label
Regulatory
Status
Tests/
Dispenser
Ventana P/N
Roche P/N
DIG
RUO
25
980-1222 06577229001
Chromosome 7 DIG Probe
DIG
RUO
25
760-1219 06443923001
Chromosome 7 Probe
DNP
CE-IVD
25
800-4342 05278899001
Chromosome 8 DIG Probe
DIG
RUO
25
760-1220 06453848001
Chromosome 10 DIG Probe
DIG
RUO
25
760-1223 06577369001
Chromosome 15 DIG Probe
DIG
CE-IVD
25
800-4459 05994926001
Chromosome 17 DIG Probe
DIG
RUO
25
980-1224 06577067001
Chromosome 17 Probe
DNP
CE-IVD
50
780-4331 05273412001
EBER Probe
FITC
CE-IVD
50
800-2842 05278660001
EGFR DNP Probe
DNP
RUO
25
980-1216 06443834001
FGFR1 DNP Probe
DNP
RUO
25
980-1217 06454216001
HER2 DNA Probe
DNP
CE-IVD
50
800-2844 05273439001
DNP(HER2)/DIG (Chr17)
CE-IVD
50
800-4422 05899826001
HPV II family 6
DNP
CE-IVD
50
800-2220 05278546001
HPV III family 16 Probe
DNP
CE-IVD
50
800-4295 05278856001
IGF1R DNP Probe
DNP
CE-IVD
25
800-4458 5994934001
KAPPA Probe
FITC
CE-IVD
50
800-2843 05278678001
HER2 Dual ISH DNA Probe CKTL
LAMBDA Probe
FITC
CE-IVD
50
800-2844 05278686001
MET DNA Probe
DNP
CE-IVD
25
800-4372 05575311001
MYC DNP Probe
DNP
RUO
25
980-1218 06454267001
PIK3CA DNP Probe
DNP
RUO
25
980-1226 06620400001
PTEN DNP Probe
DNP
RUO
25
980-1225 06621066001
TOP2A DNP Probe
DNP
RUO
25
980-1227 06621112001
www.ventana.com | www.roche.com 31
IHC & ish | Ancillary Reagents
Ancillary Reagents
Amplification
Product
Catalogue Number
Description
Quantity
Amplification Kit
760-080 05266114001 May be used in conjunction with VENTANA IHC detection kits to increase the
signal intensity of weak staining mouse and rabbit primary antibodies. Reagents
are provided pre-diluted and ready-to-use. Components: Amplifier A, Amplifier B
100 tests
Amplification HQ Kit
760-052 06472320001 Enzyme-based target detection amplification detection kit utilising our
proprietary HQ hapten technology. The DISCOVERY Amp HQ kit, in conjunction
with 1) an anti-HQ Multimer, 2) an OmniMap or UltraMap HRP Multimer and
3) a chromogenic detection kit, enables the enhancement of the chromogenic
signal in standard immunohistochemistry (IHC) and in situ hybridisation (ISH)
protocols. For Research Use Only. Not for use in diagnostic procedures.
50 tests
Anti-HQ AP Multimer
760-4521 06472311001 Mouse anti-HQ Alkaline Phosphatase Multimer provides signal amplification
50 tests
without loss of resolution. In conjunction with 1) the DISCOVERY Amp HQ Kit, 2)
an OmniMap or UltraMap HRP Multimer and 3) a chromogenic detection kit, the
DISCOVERY anti-HQ AP Multimer provides the ability to enhance the chromogenic
signal in standard immunohistochemistry (IHC) and in situ hybridisation (ISH)
protocols. For Research Use Only. Not for use in diagnostic procedures.
Anti-HQ HRP Multimer 760-4602 06442544001 Mouse anti-HQ Horseradish Peroxidase (HRP) Multimer provides signal
amplification without loss of resolution. In conjunction with 1) the DISCOVERY
Amp HQ kit, 2) an OmniMap or UltraMap HRP Multimer and 3) a chromogenic
detection kit, DISCOVERY anti-HQ HRP Multimer provides the ability to enhance
the chromogenic signal in standard immunohistochemistry (IHC) and in situ
hybridisation (ISH) protocols. For Research Use Only. Not for use in diagnostic
procedures.
AmpMap with TSA
50 tests
760-121 05266335001 The AmpMap kit is a multiple step amplification system that relies on the use of
tyramide. This kit enhances the staining obtained with the biotin-based detection
kits (DABMap, RedMap, BlueMap) in IHC and ISH. For use on the DISCOVERY
series systems. For Research Use Only. Not for use in diagnostic
procedures. Components: PO Block, SA-HRP, TSA Block, TSA DNP, TSA H2O2,
Anti-DNP, Anti-Rb Biotin
Antibody diluents
Product
32 Catalogue Number
Description
Quantity
Antibody Dilution
Buffer
ADB250 05280524001 Antibody Dilution Buffer contains phosphate-buffered saline and stabilising
protein and is intended to stabilise diluted antibodies when stored at 2 °C - 8 °C;
ready-to-use. For Research Use Only. Not for use in diagnostic procedures.
250 mL
bottle
DISCOVERY Antibody
Diluent
760-108 05266319001 Phosphate-based diluent for titration and usage of antibodies. For Research Use
Only. Not for use in diagnostic procedures.
100 mL
bottle
PSS Diluent
760-212 05266815001 Tris-based diluent for titration of antibodies, including phospho-site specific
antibodies. For Research Use Only. Not for use in diagnostic procedures.
100 mL
bottle
Ancillary Reagents | IHC & ish
Application kits
Product
Catalogue Number
Description
Quantity
DISCOVERY
Biotinylated
Rabbit Secondary
Antibody
760-4507 06135234001 Biotinylated goat anti-rabbit lgG in a protein block for use with detection kits. For
Research Use Only. Not for use in diagnostic procedures.
250 tests
DISCOVERY MoMap
Kit
760-137 05266416001
The MoMap Kit assists with use of mouse monoclonal antibodies on mouse tissue
or xenograft tissue. The kit uses a blocking system that increases the specificity
of the secondary antibody anti-mouse for the primary antibody and decreases the
background usually observed. This kit works with the biotin-based detection kit
(DABMap, RedMap, BlueMap) in IHC and ISH. For Research Use Only. Not for use
in diagnostic procedures.
Components: Solution A (biotinylated anti-mouse antibody), Solution B
(Non-immune mouse immunoglobulin)
125 tests
RiboMap Kit
760-102 05266190001
The RiboMap kit has been developed for the optimisation of staining with ISH
applications on the DISCOVERY series systems and can be used for the dilution
of probe and/or pre-hybridisation. This kit contains solutions that reduce the
background, enhance the signal and improve the morphology of the tissue. For
Research Use Only. Not for use in diagnostic procedures.
125 tests
Universal Secondary
Antibody
760-4205 05268877001 Biotinylated Ig cocktail of goat anti-mouse IgG, goat anti-mouse IgM, goat antirabbit IgG and protein block. For Research Use Only. Not for use in diagnostic
procedures.
250 tests
Catalogue Number
Quantity
Blockers
Product
Description
Endogenous Biotin
Blocking Kit
760-050 05266092001 May be used to aid in the reduction of non-specific staining caused by
endogenous biotin present in cells and tissues. Blocker A specifically binds
to endogenous biotin present in the tissue; Blocker B saturates the remaining
binding sites of the egg white avidin in Blocker A, thus reducing the non-specific
staining. For use with the DISCOVERY series systems. Components: Blocker A,
Blocker B.
250 tests
Antibody Block
760-4204 05268869001 High ionic strength protein blocking solution for reduction of background. For
Research Use Only. Not for use in diagnostic procedures.
250 tests
S-Block
760-4212 05268931001 Normal serum cocktail of goat, sheep and donkey used to block non-specific
binding of primary and/or secondary antibodies. For Research Use Only. Not for
use in diagnostic procedures.
250 tests
www.ventana.com | www.roche.com 33
IHC & ish | Ancillary Reagents
Bulk solutions
Product
34 Catalogue Number
Description
Quantity
DISCOVERY Cell
Conditioning 1 (CC1)
950-500 06414575001 Ready-to-use pre-diluted solution used as a pretreatment step in the processing
of tissue samples for immunohistochemistry reactions carried out on the
DISCOVERY series systems. DISCOVERY CC1 is a tris-based buffer with a slightly
basic pH, which at elevated temperatures is capable of hydrolysing the covalent
bonds formed by formalin in tissue. Removing these bonds allows renaturation
of protein molecules and increases antibody accessibility. Often these changes
result in significant gains in antibody binding and improved signal to noise ratios.
The formulation contains an inert nanoparticle additive which creates a more
hydrophilic surface to decrease the risk of attached bubbles and non-staining
events. For Research Use Only. Not for use in diagnostic procedures.
DISCOVERY EZ Prep
(10x)
950-100 05279755001 Concentrated solution that, when diluted ten-fold, is used for paraffin removal
2 L bottle
from tissue samples during immunohistochemistry reactions. The working solution
is also used as a non-buffered diluent to dilute 2x SSC during stringency washes
during in situ hybridisation reactions carried out on DISCOVERY series systems.
For Research Use Only. Not for use in diagnostic procedures.
Liquid Coverslip
(High Temperature)
650-010 05264839001 Ready-to-use coverslip solution used as a barrier between the aqueous
reagents and the air, preventing evaporation, thereby providing a stable aqueous
environment for the immunohistochemistry or in situ hybridisation reactions
carried out on the DISCOVERY series systems.
2 L bottle
RiboWash (10x)
950-110 05266262001
Used in SSC container of DISCOVERY series systems. For Research Use Only. Not
for use in diagnostic procedures.
2 L bottle
Reaction Buffer
(10x)
950-300 05353955001 Concentrated buffered solution used to rinse slides between staining steps and
to provide a stable aqueous environment for the immunohistochemistry reactions
carried out on the DISCOVERY series systems.
2 L bottle
RiboCC
760-107 05266297001 Ready-to-use pre-diluted solution used as a pretreatment step in the processing
1 L bottle
of tissue samples for immunohistochemistry reactions carried out on the
DISCOVERY series systems. Ribo CC is a citrate-based buffer with a slightly acidic
pH, which at elevated temperatures is capable of hydrolysing the covalent bonds
formed byformalin in tissue. Removing these bonds allows renaturation of protein
molecules and increases antibody accessibility. Often these changes result in
significant gains in antibody binding and improved signal-to-noise ratios. For
Research Use Only. Not for use in diagnostic procedures.
ULTRA LCS
(Predilute)
05424534001
Solution used as a barrier between the aqueous reagents and the air, which has
been optimised for use on the DISCOVERY ULTRA automated slide stainer. This
barrier prevents evaporation, thereby providing a stable aqueous environment for
immunohistochemistry or in situ hybridisation reactions.
2 L bottle
2 L bottle
Ancillary Reagents | IHC & ish
Counterstains
Product
Catalogue Number
Description
Quantity
Bluing Reagent
760-2037 05266769001 Ready-to-use solution that can be applied after hematoxylin to change the hue of
hematoxylin to a blue colour. Single, ready-to-use dispenser.
250 tests
Hematoxylin
760-2021 05266726001 A modified Gill’s hematoxylin intended for staining cellular nuclei on slides
containing cells from frozen tissue, formalin-fixed and paraffin-embedded tissue
or cytologic preparations. Single, ready-to-use dispenser.
250 tests
Hematoxylin II
760-2208 05277965001 A modified Mayer’s hematoxylin intended for staining cellular nuclei on slides
containing cells from frozen tissue, formalin-fixed and paraffin-embedded tissue
or cytologic preparations. Single, ready-to-use dispenser.
250 tests
Red Counterstain II
780-2218 05272017001 Red Counterstain II provides pink background staining in nuclei and cytoplasm
of formalin-fixed paraffin-embedded tissue sections, which is intended to aid
microscopic bright field observation for chromogenic in situ hybridisation. Store at
2 °C - 8 °C.
100 tests
QD DAPI
760-4196 05268826001 DAPI counterstain kit designed for automated immunofluorescent nuclear staining 125 tests
of cytological preparations, frozen sections or formaldehyde-fixed paraffinembedded tissue sections. For use with the DISCOVERY series systems. For
Research Use Only. Not for use in diagnostic procedures.
Enzymes
Product
Catalogue Number
Description
Quantity
Protease 1
760-2018 05266688001 Ready-to-use endopeptidase (alkaline protease) of the serine protease family and
cleaves antigens (proteins) in the tissue section, allowing primary antibodies to
recognise and bind epitope(s). The reagent is intended for enzymatic digestion
of sections of formalin-fixed paraffin-embedded tissue. With 0.5 units/ml alkaline
protease enzyme activity, Protease 1 is our strongest enzymatic pretreatment
available for immunohistochemistry (IHC) or in situ hybridisation (ISH). For use
with the DISCOVERY series systems. Single ready-to-use dispenser.
250 tests
Protease 2
760-2019 05266696001 Ready-to-use endopeptidase (alkaline protease) of the serine protease family and
cleaves antigens (proteins) in the tissue section, allowing primary antibodies to
recognise and bind epitope(s). The reagent is intended for enzymatic digestion
of sections of formalin-fixed paraffin-embedded tissue. With 0.1 units/ml alkaline
protease enzyme activity, Protease 2 is our intermediate-strength enzymatic
pretreatment available for immunohistochemistry (IHC) or in situ hybridisation
(ISH). For use with DISCOVERY series systems. Single ready-to-use dispenser.
250 tests
Protease 3
760-2020 05266718001 Ready-to-use endopeptidase (alkaline protease) of the serine protease family and
cleaves antigens (proteins) in the tissue section, allowing primary antibodies to
recognise and bind epitope(s). The reagent is intended for enzymatic digestion of
sections of formalin-fixed paraffin-embedded tissue. With 0.02 units/ml alkaline
protease enzyme activity, Protease 3 is our mildest enzymatic pretreatment
available for immunohistochemistry (IHC) or in situ hybridisation (ISH). For use
with the DISCOVERY series systems. Single ready-to-use dispenser.
250 tests
Hybridisation buffers
Product
Catalogue Number
Description
Quantity
RiboHybe
760-104 05266254001
The RiboHybe is a stringent hybridisation buffer used for the dilution of the probe 30 mL
and/or pre-hybridisation for ISH applications on the DISCOVERY series systems. bottle
For Research Use Only. Not for use in diagnostic procedures.
www.ventana.com | www.roche.com 35
IHC & ish | Ancillary Reagents
User-fillable dispensers
User Fillable Antibody Dispensers
Product
250 Test Antibody # 1
250 Test Antibody # 2
250 Test Antibody # 3
250 Test Antibody # 4
250 Test Antibody # 5
250 Test Antibody # 6
250 Test Antibody # 7
250 Test Antibody # 8
250 Test Antibody # 9
250 Test Antibody # 10
250 Test Antibody # 11
250 Test Antibody # 12
250 Test Antibody # 13
250 Test Antibody # 14
250 Test Antibody # 15
250 Test Antibody # 16
250 Test Antibody # 17
250 Test Antibody # 18
250 Test Antibody # 19
250 Test Antibody # 20
250 Test Antibody # 21
250 Test Antibody # 22
250 Test Antibody # 23
250 Test Antibody # 24
250 Test Antibody # 25
250 Test Antibody # 26
250 Test Antibody # 27
250 Test Antibody # 28
250 Test Antibody # 29
36 Part Number
770-001 05269857001
770-002 05269865001
770-003 05269873001
770-004 05269881001
770-005 05269890001
770-006 05269903001
770-007 05269911001
770-008 05269920001
770-009 05269938001
770-010 05269946001
770-011 05269954001
770-012 05269962001
770-013 05269989001
770-014 05269997001
770-015 05270006001
770-016 05270014001
770-017 05270022001
770-018 05270049001
770-019 05270057001
770-020 05270065001
770-021 05270073001
770-022 05270081001
770-023 05270090001
770-024 05270103001
770-025 05270111001
770-026 05270120001
770-027 05270138001
770-028 05270146001
770-029 05270154001
Product
250 Test Antibody # 30
250 Test Antibody # 31
250 Test Antibody # 32
250 Test Antibody # 33
250 Test Antibody # 34
250 Test Antibody # 35
250 Test Antibody # 36
250 Test Antibody # 37
250 Test Antibody # 38
250 Test Antibody # 39
250 Test Antibody # 40
250 Test Antibody # 41
250 Test Antibody # 42
250 Test Antibody # 43
250 Test Antibody # 44
250 Test Antibody # 45
250 Test Antibody # 46
250 Test Antibody # 47
250 Test Antibody # 48
250 Test Antibody # 49
250 Test Antibody # 50
Part Number
770-030 05270162001
770-031 05270189001
770-032 05270197001
770-033 05270219001
770-034 05270227001
770-035 05270235001
770-036 05270243001
770-037 05270251001
770-038 05270260001
770-039 05270278001
770-040 05270286001
770-041 05270294001
770-042 05270308001
770-043 05270316001
770-044 05270324001
770-045 05270332001
770-046 05270359001
770-047 05270367001
770-048 05270375001
770-049 05270383001
770-050 05270391001
Ancillary Reagents | IHC & ish
250 Test Detection
Product
250 Test Detection # 1
250 Test Detection # 2
250 Test Detection # 3
250 Test Detection # 4
250 Test Detection # 5
250 Test Detection # 6
250 Test Detection # 7
250 Test Detection # 8
250 Test Detection # 9
250 Test Detection # 10
250 Test Detection # 11
250 Test Detection # 12
250 Test Detection # 13
250 Test Detection # 14
250 Test Detection # 15
250 Test Detection # 16
250 Test Detection # 17
250 Test Detection # 18
250 Test Detection # 19
250 Test Detection # 20
250 Test Probes
Part Number
960-911 05280192001
960-912 05280206001
960-913 05280214001
960-914 05280222001
960-915 05280249001
960-916 05280257001
960-917 05280265001
960-918 05280273001
960-919 05280281001
960-920 05280290001
960-921 05280303001
960-922 05280311001
960-923 05280320001
960-924 05280338001
960-925 05280346001
960-926 05280354001
960-927 05280362001
960-928 05280389001
960-929 05280397001
960-930 05280419001
250 Test Blockers
Product
250 Test Blocker # 1
250 Test Blocker # 2
250 Test Blocker # 3
250 Test Blocker # 4
250 Test Blocker # 5
Part Number
760-4206 05268885001
760-4207 05268893001
760-4208 05268907001
760-4209 05268915001
760-4210 05268923001
Product
250 Test Probe # 1
250 Test Probe # 2
250 Test Probe # 3
250 Test Probe # 4
250 Test Probe # 5
250 Test Probe # 6
250 Test Probe # 7
250 Test Probe # 8
250 Test Probe # 9
250 Test Probe # 10
250 Test Probe # 11
250 Test Probe # 12
250 Test Probe # 13
250 Test Probe # 14
250 Test Probe # 15
250 Test Probe # 16
250 Test Probe # 17
250 Test Probe # 18
250 Test Probe # 19
250 Test Probe # 20
250 Test Probe # 21
250 Test Probe # 22
250 Test Probe # 23
250 Test Probe # 24
250 Test Probe # 25
Part Number
960-761 05279828001
960-762 05279836001
960-763 05279844001
960-764 05279852001
960-765 05279879001
960-766 05279887001
960-767 05279895001
960-768 05279909001
960-769 05279917001
960-770 05279925001
960-771 05279933001
960-772 05279941001
960-773 05279950001
960-774 05279968001
960-775 05279976001
960-776 05279984001
960-777 05279992001
960-778 05280001001
960-779 05280010001
960-780 05280028001
960-781 05280036001
960-782 05280044001
960-783 05280052001
960-784 05280079001
960-785 05280087001
250 Test Pretreatments
Product
250 Test Pretreatment # 1
250 Test Pretreatment # 2
250 Test Pretreatment # 3
250 Test Pretreatment # 4
250 Test Pretreatment # 5
250 Test Pretreatment # 6
250 Test Pretreatment # 7
250 Test Pretreatment # 8
250 Test Pretreatment # 9
Part Number
960-901 05280095001
960-902 05280109001
960-903 05280117001
960-904 05280125001
960-905 05280133001
960-906 05280141001
960-907 05280150001
960-908 05280168001
960-909 05280176001
www.ventana.com | www.roche.com 37
IHC & ish | Ancillary Reagents
50 Test Prep Kits
Product
50 Test Prep Kit # 501
50 Test Prep Kit # 502
50 Test Prep Kit # 503
50 Test Prep Kit # 504
50 Test Prep Kit # 505
50 Test Prep Kit # 506
50 Test Prep Kit # 507
50 Test Prep Kit # 508
50 Test Prep Kit # 509
50 Test Prep Kit # 510
50 Test Prep Kit # 511
50 Test Prep Kit # 512
50 Test Prep Kit # 513
50 Test Prep Kit # 514
50 Test Prep Kit # 515
50 Test Prep Kit # 516
50 Test Prep Kit # 517
50 Test Prep Kit # 518
50 Test Prep Kit # 519
50 Test Prep Kit # 520
50 Test Prep Kit # 521
50 Test Prep Kit # 522
50 Test Prep Kit # 523
50 Test Prep Kit # 524
50 Test Prep Kit # 525
Part Number
783-3457 05275814001
783-3458 05275822001
783-3459 05275849001
783-3460 05275857001
783-3461 05275865001
783-3462 05275873001
783-3463 05275881001
783-3464 05275890001
783-3465 05275903001
783-3466 05275911001
783-3467 05275920001
783-3468 05275938001
783-3469 05275946001
783-3470 05275954001
783-3471 05275962001
783-3472 05275989001
783-3473 05275997001
783-3474 05276004001
783-3475 05276012001
783-3476 05276039001
783-3477 05276047001
783-3478 05276055001
783-3479 05276063001
783-3480 05276071001
783-3481 05276080001
100 Test Prep Kits
Product
100 Test Prep Kit # 1
100 Test Prep Kit # 2
100 Test Prep Kit # 3
100 Test Prep Kit # 4
100 Test Prep Kit # 5
100 Test Prep Kit # 6
100 Test Prep Kit # 7
100 Test Prep Kit # 8
100 Test Prep Kit # 9
100 Test Prep Kit # 10
100 Test Prep Kit # 11
100 Test Prep Kit # 12
100 Test Prep Kit # 13
100 Test Prep Kit # 14
100 Test Prep Kit # 15
100 Test Prep Kit # 16
100 Test Prep Kit # 17
100 Test Prep Kit # 18
38 Part Number
783-2851 05273617001
783-2852 05273625001
783-2853 05273633001
783-2854 05273641001
783-2855 05273650001
783-2856 05273668001
783-2857 05273676001
783-2858 05273684001
783-2859 05273692001
783-2860 05273706001
783-2861 05273714001
783-2862 05273722001
783-2863 05273749001
783-2864 05273757001
783-2865 05273765001
783-2866 05273773001
783-2867 05273781001
783-2868 05273790001
Product
100 Test Prep Kit # 19
100 Test Prep Kit # 20
100 Test Prep Kit # 21
100 Test Prep Kit # 22
100 Test Prep Kit # 23
100 Test Prep Kit # 24
100 Test Prep Kit # 25
100 Test Prep Kit # 26
100 Test Prep Kit # 27
100 Test Prep Kit # 28
100 Test Prep Kit # 29
100 Test Prep Kit # 30
100 Test Prep Kit # 31
100 Test Prep Kit # 32
100 Test Prep Kit # 33
100 Test Prep Kit # 34
100 Test Prep Kit # 35
100 Test Prep Kit # 36
100 Test Prep Kit # 37
100 Test Prep Kit # 38
100 Test Prep Kit # 39
100 Test Prep Kit # 40
100 Test Prep Kit # 41
100 Test Prep Kit # 42
100 Test Prep Kit # 43
100 Test Prep Kit # 44
100 Test Prep Kit # 45
100 Test Prep Kit # 46
100 Test Prep Kit # 47
100 Test Prep Kit # 48
100 Test Prep Kit # 49
100 Test Prep Kit # 50
100 Test Prep Kit # 51
100 Test Prep Kit # 52
100 Test Prep Kit # 53
100 Test Prep Kit # 54
100 Test Prep Kit # 55
100 Test Prep Kit # 56
100 Test Prep Kit # 57
100 Test Prep Kit # 58
100 Test Prep Kit # 59
100 Test Prep Kit # 60
100 Test Prep Kit # 61
100 Test Prep Kit # 62
100 Test Prep Kit # 63
100 Test Prep Kit # 64
100 Test Prep Kit # 65
100 Test Prep Kit # 66
Part Number
783-2869 05273803001
783-2870 05273811001
783-2871 05273820001
783-2872 05273838001
783-2873 05273846001
783-2874 05273854001
783-2875 05273862001
783-2876 05273889001
783-2877 05273897001
783-2878 05273919001
783-2879 05273927001
783-2880 05273935001
783-2881 05273943001
783-2882 05273951001
783-2883 05273960001
783-2884 05273978001
783-2885 05273986001
783-2886 05273994001
783-2887 05274001001
783-2888 05274010001
783-2889 05274028001
783-2890 05274036001
783-2891 05274044001
783-2892 05274052001
783-2893 05274079001
783-2894 05274087001
783-2895 05274095001
783-2896 05274109001
783-2897 05274117001
783-2898 05274125001
783-2899 05274133001
783-2900 05274141001
783-3007 05274168001
783-3008 05274176001
783-3009 05274184001
783-3010 05274192001
783-3011 05274206001
783-3012 05274214001
783-3013 05274222001
783-3014 05274249001
783-3015 05274257001
783-3016 05274265001
783-3017 05274273001
783-3018 05274281001
783-3019 05274290001
783-3020 05274303001
783-3021 05274311001
783-3022 05274320001
Ancillary Reagents | IHC & ish
Product
100 Test Prep Kit # 67
100 Test Prep Kit # 68
100 Test Prep Kit # 69
100 Test Prep Kit # 70
100 Test Prep Kit # 71
100 Test Prep Kit # 72
100 Test Prep Kit # 73
100 Test Prep Kit # 74
100 Test Prep Kit # 75
100 Test Prep Kit # 76
100 Test Prep Kit # 77
100 Test Prep Kit # 78
100 Test Prep Kit # 79
100 Test Prep Kit # 80
100 Test Prep Kit # 81
100 Test Prep Kit # 82
100 Test Prep Kit # 83
100 Test Prep Kit # 84
100 Test Prep Kit # 85
100 Test Prep Kit # 86
100 Test Prep Kit # 87
100 Test Prep Kit # 88
100 Test Prep Kit # 89
100 Test Prep Kit # 90
100 Test Prep Kit # 91
100 Test Prep Kit # 92
100 Test Prep Kit # 93
100 Test Prep Kit # 94
100 Test Prep Kit # 95
100 Test Prep Kit # 96
100 Test Prep Kit # 97
100 Test Prep Kit # 98
100 Test Prep Kit # 99
100 Test Prep Kit # 100
100 Test Prep Kit # 101
100 Test Prep Kit # 102
100 Test Prep Kit # 103
100 Test Prep Kit # 104
100 Test Prep Kit # 105
100 Test Prep Kit # 106
100 Test Prep Kit # 107
100 Test Prep Kit # 108
100 Test Prep Kit # 109
100 Test Prep Kit # 110
100 Test Prep Kit # 111
100 Test Prep Kit # 112
100 Test Prep Kit # 113
100 Test Prep Kit # 114
Part Number
783-3023 05274338001
783-3024 05274346001
783-3025 05274354001
783-3026 05274362001
783-3027 05274389001
783-3028 05274397001
783-3029 05274419001
783-3030 05274427001
783-3031 05274435001
783-3032 05274443001
783-3033 05274451001
783-3034 05274460001
783-3035 05274478001
783-3036 05274486001
783-3037 05274494001
783-3038 05274508001
783-3039 05274516001
783-3040 05274524001
783-3041 05274532001
783-3042 05274559001
783-3043 05274567001
783-3044 05274575001
783-3045 05274583001
783-3046 05274591001
783-3047 05274605001
783-3048 05274613001
783-3049 05274621001
783-3050 05274630001
783-3051 05274648001
783-3052 05274656001
783-3053 05274664001
783-3054 05274672001
783-3055 05274699001
783-3056 05274702001
783-3057 05274729001
783-3058 05274737001
783-3059 05274745001
783-3060 05274753001
783-3061 05274761001
783-3062 05274770001
783-3063 05274788001
783-3064 05274796001
783-3065 05274800001
783-3066 05274818001
783-3067 05274826001
783-3068 05274834001
783-3069 05274842001
783-3070 05274869001
Product
100 Test Prep Kit # 115
100 Test Prep Kit # 116
100 Test Prep Kit # 117
100 Test Prep Kit # 118
100 Test Prep Kit # 119
100 Test Prep Kit # 120
100 Test Prep Kit # 121
100 Test Prep Kit # 122
100 Test Prep Kit # 123
100 Test Prep Kit # 124
100 Test Prep Kit # 125
100 Test Prep Kit # 126
100 Test Prep Kit # 127
100 Test Prep Kit # 128
100 Test Prep Kit # 129
100 Test Prep Kit # 130
100 Test Prep Kit # 131
100 Test Prep Kit # 132
100 Test Prep Kit # 133
100 Test Prep Kit # 134
100 Test Prep Kit # 135
100 Test Prep Kit # 136
100 Test Prep Kit # 137
100 Test Prep Kit # 138
100 Test Prep Kit # 139
100 Test Prep Kit # 140
100 Test Prep Kit # 141
100 Test Prep Kit # 142
100 Test Prep Kit # 143
100 Test Prep Kit # 144
100 Test Prep Kit # 145
100 Test Prep Kit # 146
100 Test Prep Kit # 147
100 Test Prep Kit # 148
100 Test Prep Kit # 149
100 Test Prep Kit # 150
100 Test Prep Kit # 151
100 Test Prep Kit # 152
100 Test Prep Kit # 153
100 Test Prep Kit # 154
100 Test Prep Kit # 155
100 Test Prep Kit # 156
100 Test Prep Kit # 157
100 Test Prep Kit # 158
100 Test Prep Kit # 159
100 Test Prep Kit # 160
100 Test Prep Kit # 161
100 Test Prep Kit # 162
Part Number
783-3071 05274877001
783-3072 05274885001
783-3073 05274893001
783-3074 05274907001
783-3075 05274915001
783-3076 05274923001
783-3077 05274931001
783-3078 05274940001
783-3079 05274958001
783-3080 05274966001
783-3081 05274974001
783-3082 05274982001
783-3083 05275008001
783-3084 05275016001
783-3085 05275024001
783-3086 05275032001
783-3087 05275059001
783-3088 05275067001
783-3089 05275075001
783-3090 05275083001
783-3091 05275091001
783-3092 05275105001
783-3093 05275113001
783-3094 05275121001
783-3095 05275130001
783-3096 05275148001
783-3097 05275156001
783-3098 05275164001
783-3099 05275172001
783-3100 05275199001
783-3101 05275202001
783-3102 05275229001
783-3103 05275237001
783-3104 05275245001
783-3105 05275253001
783-3106 05275261001
783-3107 05275270001
783-3108 05275288001
783-3109 05275296001
783-3110 05275300001
783-3111
05275318001
783-3112 05275326001
783-3113 05275334001
783-3114 05275342001
783-3115 05275369001
783-3116 05275377001
783-3117 05275385001
783-3118 05275393001
www.ventana.com | www.roche.com 39
IHC & ish | Ancillary Reagents
Product
100 Test Prep Kit # 163
100 Test Prep Kit # 164
100 Test Prep Kit # 165
100 Test Prep Kit # 166
100 Test Prep Kit # 167
100 Test Prep Kit # 168
100 Test Prep Kit # 169
100 Test Prep Kit # 170
100 Test Prep Kit # 171
100 Test Prep Kit # 172
100 Test Prep Kit # 173
100 Test Prep Kit # 174
100 Test Prep Kit # 175
100 Test Prep Kit # 176
100 Test Prep Kit # 177
100 Test Prep Kit # 178
100 Test Prep Kit # 179
100 Test Prep Kit # 180
100 Test Prep Kit # 181
100 Test Prep Kit # 182
100 Test Prep Kit # 183
100 Test Prep Kit # 184
100 Test Prep Kit # 185
100 Test Prep Kit # 186
100 Test Prep Kit # 187
100 Test Prep Kit # 188
100 Test Prep Kit # 189
100 Test Prep Kit # 190
100 Test Prep Kit # 191
100 Test Prep Kit # 192
100 Test Prep Kit # 193
100 Test Prep Kit # 194
100 Test Prep Kit # 195
100 Test Prep Kit # 196
100 Test Prep Kit # 197
100 Test Prep Kit # 198
100 Test Prep Kit # 199
100 Test Prep Kit # 200
Part Number
783-3119 05275407001
783-3120 05275415001
783-3121 05275423001
783-3122 05275431001
783-3123 05275440001
783-3124 05275458001
783-3125 05275466001
783-3126 05275474001
783-3127 05275482001
783-3128 05275504001
783-3129 05275512001
783-3130 05275539001
783-3131 05275547001
783-3132 05275555001
783-3133 05275563001
783-3134 05275571001
783-3135 05275580001
783-3136 05275598001
783-3137 05275601001
783-3138 05275610001
783-3139 05275628001
783-3140 05275636001
783-3141 05275644001
783-3142 05275652001
783-3143 05275679001
783-3144 05275687001
783-3145 05275695001
783-3146 05275709001
783-3147 05275717001
783-3148 05275725001
783-3149 05275733001
783-3150 05275741001
783-3151 05275750001
783-3152 05275768001
783-3153 05275776001
783-3154 05275784001
783-3155 05275792001
783-3156 05275806001
250 Test Prep Kits
Product
250 Test Prep Kit # 1
250 Test Prep Kit # 2
250 Test Prep Kit # 3
250 Test Prep Kit # 4
250 Test Prep Kit # 5
250 Test Prep Kit # 6
250 Test Prep Kit # 7
40 Part Number
786-2851 05276284001
786-2852 05276292001
786-2853 05276306001
786-2854 05276314001
786-2855 05276322001
786-2856 05276349001
786-2857 05276357001
Product
250 Test Prep Kit # 8
250 Test Prep Kit # 9
250 Test Prep Kit # 10
250 Test Prep Kit # 11
250 Test Prep Kit # 12
250 Test Prep Kit # 13
250 Test Prep Kit # 14
250 Test Prep Kit # 15
250 Test Prep Kit # 16
250 Test Prep Kit # 17
250 Test Prep Kit # 18
250 Test Prep Kit # 19
250 Test Prep Kit # 20
250 Test Prep Kit # 21
250 Test Prep Kit # 22
250 Test Prep Kit # 23
250 Test Prep Kit # 24
250 Test Prep Kit # 25
250 Test Prep Kit # 26
250 Test Prep Kit # 27
250 Test Prep Kit # 28
250 Test Prep Kit # 29
250 Test Prep Kit # 30
250 Test Prep Kit # 31
250 Test Prep Kit # 32
250 Test Prep Kit # 33
250 Test Prep Kit # 34
250 Test Prep Kit # 35
250 Test Prep Kit # 36
250 Test Prep Kit # 37
250 Test Prep Kit # 38
250 Test Prep Kit # 39
250 Test Prep Kit # 40
250 Test Prep Kit # 41
250 Test Prep Kit # 42
250 Test Prep Kit # 43
250 Test Prep Kit # 44
250 Test Prep Kit # 45
250 Test Prep Kit # 46
250 Test Prep Kit # 47
250 Test Prep Kit # 48
250 Test Prep Kit # 49
250 Test Prep Kit # 50
250 Test Prep Kit # 51
250 Test Prep Kit # 52
250 Test Prep Kit # 53
250 Test Prep Kit # 54
250 Test Prep Kit # 55
Part Number
786-2858 05276365001
786-2859 05276373001
786-2860 05276381001
786-2861 05276390001
786-2862 05276403001
786-2863 05276411001
786-2864 05276420001
786-2865 05276438001
786-2866 05276446001
786-2867 05276454001
786-2868 05276462001
786-2869 05276489001
786-2870 05276497001
786-2871 05276519001
786-2872 05276527001
786-2873 05276535001
786-2874 05276543001
786-2875 05276551001
786-2876 05276560001
786-2877 05276578001
786-2878 05276586001
786-2879 05276594001
786-2880 05276608001
786-2881 05276616001
786-2882 05276624001
786-2883 05276632001
786-2884 05276659001
786-2885 05276667001
786-2886 05276675001
786-2887 05276683001
786-2888 05276691001
786-2889 05276705001
786-2890 05276713001
786-2891 05276721001
786-2892 05276730001
786-2893 05276748001
786-2894 05276756001
786-2895 05276764001
786-2896 05276772001
786-2897 05276799001
786-2898 05276802001
786-2899 05276829001
786-2900 05276837001
786-3007 05276845001
786-3008 05276853001
786-3009 05276861001
786-3010 05276870001
786-3011 05276888001
Ancillary Reagents | IHC & ish
Product
250 Test Prep Kit # 56
250 Test Prep Kit # 57
250 Test Prep Kit # 58
250 Test Prep Kit # 59
250 Test Prep Kit # 60
250 Test Prep Kit # 61
250 Test Prep Kit # 62
250 Test Prep Kit # 63
250 Test Prep Kit # 64
250 Test Prep Kit # 65
250 Test Prep Kit # 66
250 Test Prep Kit # 67
250 Test Prep Kit # 68
250 Test Prep Kit # 69
250 Test Prep Kit # 70
250 Test Prep Kit # 71
250 Test Prep Kit # 72
250 Test Prep Kit # 73
250 Test Prep Kit # 74
250 Test Prep Kit # 75
250 Test Prep Kit # 76
250 Test Prep Kit # 77
250 Test Prep Kit # 78
250 Test Prep Kit # 79
250 Test Prep Kit # 80
250 Test Prep Kit # 81
250 Test Prep Kit # 82
250 Test Prep Kit # 83
250 Test Prep Kit # 84
250 Test Prep Kit # 85
250 Test Prep Kit # 86
250 Test Prep Kit # 87
250 Test Prep Kit # 88
250 Test Prep Kit # 89
250 Test Prep Kit # 90
250 Test Prep Kit # 91
250 Test Prep Kit # 92
250 Test Prep Kit # 93
250 Test Prep Kit # 94
250 Test Prep Kit # 95
250 Test Prep Kit # 96
250 Test Prep Kit # 97
250 Test Prep Kit # 98
250 Test Prep Kit # 99
250 Test Prep Kit # 100
250 Test Prep Kit # 101
250 Test Prep Kit # 102
250 Test Prep Kit # 103
Part Number
786-3012 05276896001
786-3013 05276900001
786-3014 05276918001
786-3015 05276926001
786-3016 05276934001
786-3017 05276942001
786-3018 05276969001
786-3019 05276977001
786-3020 05276985001
786-3021 05276993001
786-3022 05277019001
786-3023 05277027001
786-3024 05277035001
786-3025 05277043001
786-3026 05277051001
786-3027 05277060001
786-3028 05277078001
786-3029 05277086001
786-3030 05277094001
786-3031 05277108001
786-3032 05277116001
786-3033 05277124001
786-3034 05277132001
786-3035 05277159001
786-3036 05277167001
786-3037 05277175001
786-3038 05277183001
786-3039 05277191001
786-3040 05277205001
786-3041 05277213001
786-3042 05277221001
786-3043 05277230001
786-3044 05277248001
786-3045 05277256001
786-3046 05277264001
786-3047 05277272001
786-3048 05277299001
786-3049 05277302001
786-3050 05277329001
786-3051 05277337001
786-3052 05277345001
786-3053 05277353001
786-3054 05277361001
786-3055 05277370001
786-3056 05277388001
786-3057 05277396001
786-3058 05277400001
786-3059 05277418001
Product
250 Test Prep Kit # 104
250 Test Prep Kit # 105
250 Test Prep Kit # 106
250 Test Prep Kit # 107
250 Test Prep Kit # 108
250 Test Prep Kit # 109
250 Test Prep Kit # 110
250 Test Prep Kit # 111
250 Test Prep Kit # 112
250 Test Prep Kit # 113
250 Test Prep Kit # 114
250 Test Prep Kit # 115
250 Test Prep Kit # 116
250 Test Prep Kit # 117
250 Test Prep Kit # 118
250 Test Prep Kit # 119
250 Test Prep Kit # 120
250 Test Prep Kit # 121
250 Test Prep Kit # 122
250 Test Prep Kit # 123
250 Test Prep Kit # 124
250 Test Prep Kit # 125
250 Test Prep Kit # 126
250 Test Prep Kit # 127
250 Test Prep Kit # 128
250 Test Prep Kit # 129
250 Test Prep Kit # 130
250 Test Prep Kit # 131
250 Test Prep Kit # 132
250 Test Prep Kit # 133
250 Test Prep Kit # 134
250 Test Prep Kit # 135
250 Test Prep Kit # 136
250 Test Prep Kit # 137
250 Test Prep Kit # 138
250 Test Prep Kit # 139
250 Test Prep Kit # 140
250 Test Prep Kit # 141
250 Test Prep Kit # 142
250 Test Prep Kit # 143
250 Test Prep Kit # 144
250 Test Prep Kit # 145
250 Test Prep Kit # 146
250 Test Prep Kit # 147
250 Test Prep Kit # 148
250 Test Prep Kit # 149
250 Test Prep Kit # 150
Part Number
786-3060 05277426001
786-3061 05277434001
786-3062 05277442001
786-3063 05277469001
786-3064 05277477001
786-3065 05277485001
786-3066 05277493001
786-3067 05277507001
786-3068 05277515001
786-3069 05277523001
786-3070 05277531001
786-3071 05277540001
786-3072 05277558001
786-3073 05277566001
786-3074 05277574001
786-3075 05277582001
786-3076 05277604001
786-3077 05277612001
786-3078 05277639001
786-3079 05277647001
786-3080 05277655001
786-3081 05277663001
786-3082 05277671001
786-3083 05277680001
786-3084 05277698001
786-3085 05277701001
786-3086 05277710001
786-3087 05277728001
786-3088 05277736001
786-3089 05277744001
786-3090 05277752001
786-3091 05277779001
786-3092 05277787001
786-3093 05277795001
786-3094 05277809001
786-3095 05277817001
786-3096 05277825001
786-3097 05277833001
786-3098 05277841001
786-3099 05277850001
786-3100 05277868001
786-3101 05277876001
786-3102 05277884001
786-3103 05277892001
786-3104 05277906001
786-3105 05277914001
786-3106 05277922001
www.ventana.com | www.roche.com 41
IHC & ish | Ancillary Reagents
Counterstain dispensers
Product
250 Test Counterstain # 1
250 Test Counterstain # 2
250 Test Counterstain # 3
250 Test Counterstain # 4
250 Test Counterstain # 5
250 Test Counterstain # 6
250 Test Counterstain # 7
250 Test Counterstain # 8
250 Test Counterstain # 9
250 Test Counterstain # 10
Option dispensers
Part Number
771-741 05271720001
771-742 05271738001
771-743 05271746001
771-744 05271754001
771-745 05271762001
771-746 05271789001
771-747 05271797001
771-748 05271819001
771-749 05271827001
771-750 05271835001
Product
Part Number
250 Test Option # 1
250 Test Option # 2
250 Test Option # 3
250 Test Option # 4
250 Test Option # 5
250 Test Option # 6
250 Test Option # 7
250 Test Option # 8
250 Test Option # 9
250 Test Option # 10
771-751
771-752
771-753
771-754
771-755
771-756
771-757
771-758
771-759
771-760
05271843001
05271851001
05271860001
05271878001
05271886001
05271894001
05271908001
05271916001
05271924001
05271932001
Replacement filters
(20 Filters)
771-100 05271959001
Enzyme dispensers
Product
250 Test Enzyme # 1
250 Test Enzyme # 2
250 Test Enzyme # 3
250 Test Enzyme # 4
250 Test Enzyme # 5
250 Test Enzyme # 6
250 Test Enzyme # 7
250 Test Enzyme # 8
250 Test Enzyme # 9
250 Test Enzyme # 10
Part Number
771-721
771-722
771-723
771-724
771-725
771-726
771-727
771-728
771-729
771-730
05271517001
05271525001
05271533001
05271541001
05271550001
05271568001
05271576001
05271584001
05271592001
05271606001
Fixative dispensers
Product
250 Test Fixative # 1
250 Test Fixative # 2
250 Test Fixative # 3
250 Test Fixative # 4
250 Test Fixative # 5
250 Test Fixative # 6
250 Test Fixative # 7
250 Test Fixative # 8
250 Test Fixative # 9
250 Test Fixative # 10
42 Part Number
771-731
771-732
771-733
771-734
771-735
771-736
771-737
771-738
771-739
771-740
05271614001
05271622001
05271649001
05271657001
05271665001
05271673001
05271681001
05271690001
05271703001
05271711001
Ancillary Reagents | IHC & ish
www.ventana.com | www.roche.com 43
IHC & ish | Ancillary Reagents
44 SYMPHONY fully automated H&E system | H&E
H&E |
SYMPHONY fully automated H&E system 47
800.227.2155 | www.ventana.com 45
46 SYMPHONY fully automated H&E system | H&E
SYMPHONY
fully automated H&E system
The VENTANA SYMPHONY automated H&E slide staining platform
offers individual slide staining with fresh reagent application for
every test, protecting against tissue cross-contamination that occurs
in “dip-and-dunk” staining baths. Specially designed to enhance lab
efficiency, to improve staining quality and to mitigate risks, the
SYMPHONY system makes the H&E staining process
more precise and personal than ever before.
What’s on YOUR mind?
I need fast turnaround times and workflow efficiency.
• Free your technicians to focus on value-added work with
one-touch H&E slide processing that delivers true walkaway automation
I need to reduce errors and mitigate risks.
• Ensure positive identification with barcoded slides
• Protect against cross-contamination with individual slide
staining for every slide
• Reduce technician exposure to toxins with xylene-free
SYMPHONY Clear
I need to provide accurate results so physicians can make
accurate diagnoses.
• Count on consistent, reproducible results throughout the
day with fresh reagent application on every slide
• Improve diagnostic capability with excellent visualisation
of micro-anatomic detail
www.ventana.com | www.roche.com 47
H&E | SYMPHONY fully automated H&E system

Specifications
General Characteristics
Capability
• Provides continuous loading of up to 500 slides at a time with throughput of approximately 160-200 slides per
hour. Universal slide tray holds up to 20 individual slides and can be stacked or “nested” for pathologist review.
“Slide Detect” ID—slide tracking supporting multiple barcode formats
• Simultaneous processing of multiple slide trays including drying, deparaffinisation, staining and coverslipping
Reagents
• All SYMPHONY solutions are sealed, pre-packaged, ready-to-use and monitored with RFID for inventory
management. SYMPHONY solutions can be changed “on the fly” without process interruption
DI Water Supply
• NCCLS type II or type III DI water quality flow of greater than 650 ml/min (22 oz/min) while maintaining a
dynamic pressure of greater than 18.9 psi static pressure to 30 psi
Communication
• Standard category 5, RJ 45 network port, located within 426 cm (14’) of the left side of the instrument Network
port with TCP/IP ports 80 and 443 open
Configuration
• Free standing
Certifications
• CSA (C and US indicators), EMC, CE and C-TICK compliant
Features
• CareGiver remote support—an automated remote monitoring and diagnostics solution that enables
continuous monitoring and remote service
• Fresh solutions are used for every slide, resulting in consistent and reproducible results
Environmental Requirements
Ventilation
• The facility ventilation duct should be 7.62 cm (3”) in diameter and be located
between 31 cm to 457 cm (1’ and 15’) of instrument. The ventilation flow
specification must be a minimum of 35 cfm and a maximum of 70 cfm
Liquid Waste Disposal
• Location of drain must be within 457 cm (15’) of right side of instrument and
not exceed 91 cm (3’) in height
Electrical Specifications
• Dedicated/isolated 20-amp circuit
• 230 ± 10% volts nominal AC, 50/60 Hz - NEMA 6-20R standard receptacle
Physical Characteristics
Space requirements
48 • Recommended width is greater than 249 cm (98”). This will allow doors to
open 180 degrees
• Height must be greater than 219 cm (86”); (off casters, levelled and
ventilated)
• Depth must be greater than 131 cm (51.5”); this is spaced 13 cm (5") from
wall
• Instrument physical dimensions (H x W x D): 188 cm x 125 cm x 72 cm (74” x
49” x 28”)
SYMPHONY fully automated H&E system | H&E
Ordering Information
Product
Part Number
Description
Quantity
SYMPHONY
Staining System
900-SYM3 06114270001 Fully automated H&E staining platform individually processing samples
from drying through staining and glass coverslipping.
1
SYMPHONY B
900-204 05279496001
Intended to be used as a bluing reagent. When used in conjunction with
SYMPHONY N1 and N2+, SYMPHONY B will change the hue of nuclear
staining from purple to blue.
1 L box
SYMPHONY C
900-202 05279470001
Intended for staining cytoplasmic and other non-nuclear components
varying shades of red to pink providing excellent differentiation between
collagen, smooth muscle and other eosinophilic structures.
1 L box
SYMPHONY Clear
900-209 05279518001
Xylene-free solution used for the deparaffinisation and clearing of tissue
sections during the staining process.
2 L bottle
SYMPHONY D
900-210 05279526001
Used for the differentiation of nuclear components stained with
SYMPHONY N2+ in regressive staining protocols.
1 L box
SYMPHONY N1
900-201 05279461001
Intended for staining nuclei and other basophilic cell structures purple to
dark purple; used for progressive staining.
1 L box
SYMPHONY N2+
900-213 05279542001
Intended for staining nuclei and other basophilic cell structures dark
purple to black; used for progressive staining.
1 L box
SYMPHONY W
900-203 05279488001
Wash solution used in rinsing steps that occur between aqueous
applications during the staining process.
1 L box
SYMPHONY N2+
Cleaning Kit
900-217 05279593001
Used for cleaning SYMPHONY N2+ lines.
1 kit
Removes moisture from air, creating optimal humidity within the
coverslipping module.
1 filter
2094800 05258898001
SYMPHONY Tray Kit
(25 mm)
900-301 05279631001
Replacement trays; each tray accommodates 20 slides.
5 trays/pack
SYMPHONY Tray Kit
(26 mm)
900-302 05279674001
Replacement trays; each tray accommodates 20 slides.
5 trays/pack
OPTISURE Glass
Coverslips
900-221 05448590001
Specialised glass coverslips applied following the staining and
dehydration steps of the SYMPHONY staining process to provide
enhanced optical clarity and archivability to stained tissue sections.
OPTISURE coverslips have a dry mounting medium pre-applied and are
packaged in cassettes that are loaded onto the SYMPHONY System.
1440
(12 cassettes of
120 coverslips)
SYMPHONY
Desiccant Filter
www.ventana.com | www.roche.com 49
50 Digital Pathology |
iScan Coreo slide scanner 53
Virtuoso image management software 57
www.ventana.com | www.roche.com 51
52 iScan Coreo slide scanner | Digital Pathology

iScan Coreo
slide scanner
The VENTANA iScan Coreo slide scanner provides high quality brightfield
slide scanning enabling digital case review, sharing and telepathology. Paired
with our VENTANA Virtuoso image management software, iScan Coreo
provides users with a complete digital pathology and workflow solution.
Image acquisition through to customised reporting contributes towards
operational efficiencies and productivity in the lab.
What’s on YOUR mind?
I need to create a digital image archive.
• Access virtual image archives for case sharing
and collaboration
• Reduce slide handling errors
• Improve slide availability, portability
I need an effective way to review frozen sections.
• Use the “Live Mode” feature as a live microscope to view
tissue sections
• Enable the pathologist to render a review outside of the
surgery suite with remote viewing
• Reduce turnaround time
I need a solution that is easy to adopt
and implement into my lab.
• Benchtop scanner with a small footprint holding up
to 160 slides
• Choose from multiple acquisition options to suit your lab’s
financial considerations
• Experience world-class training and support from our
industry-leading customer support organisation
• Implement IT integration in collaboration with Roche IT
Specialists
www.ventana.com | www.roche.com 53
Digital Pathology | iScan Coreo slide scanner

Specifications
General Characteristics
Computer
• Intel-based PC, dual core, dual Xeon processor
• Storage: 160 SATA / 12 GB, CD/DVD Burner
• Connectivity: GIGABIT Ethernet ports
Computer monitor
• Resolution: flat panel high resolution monitor (1920x1200) Size: 24 inch
Input format
• 25 mm x 75 mm (1” x 3”) microscope slides
Slide capacity
• 1 to 160 slides using 8 standard Sakura baskets in an integrated rack
Automated turret
• Turret with support for four microscope objectives
Objectives
• Olympus 4X (0.1 NA), 10X (0.3 NA), 20X (0.5 NA) and 40X (0.75 NA)
Scanning resolution
• 2.5 μm/pixel at 4X, 1 μm/pixel at 10X, 0.46 μm/pixel at 20X, 0.23 μm/pixel at 40X
Barcode capability
• 1D and 2D barcode reading capability
Light source
• Integrated LED
Configuration
• Free standing
Light scan
• Automated barcode reading, tissue identification, auto focus, scanning and image compression
Manual scan
• User-configurable scan area for single or batched slides in manual mode
LCD
• 5.5” diagonal full colour display 320 x 240 resolution
Scan viewing
• 24-bit true colour
Slide storage format
• Customisable to: JPEG 2000, BIF and TIFF
Features
• Only whole slide scanner with an automated turret with four objectives, allowing optical brightfield scanning
at 4X, 10X, 20X and 40X within one batch
• Performs volume scanning with up to 15 z-stacks
• Live Mode application supports remote microscopy; the iScan Coreo can be remotely accessed to view a live
digital image of the frozen sections at 1X to 40X magnifications in multiple planes
• Walk-away automation with 160 slide capacity
Environmental Requirements
Heat
• 400 BTU/Hr idle, 1000 BTU/Hr running
Room Temperature
• 20 ºC to 32 ºC (68 ºF to 90 ºF)
Humidity
• 10% to 90%, non-condensing
Electrical Specifications
Voltage
• 110-220 VAC
Output capacity
• 400 Watts (includes light source)
Frequency
• 50/60 Hz
Safety Certifications
Compliance
• CE, UL
Physical Characteristics
Size (W x D x H)
54 • 111.76 x 84.07 x 158.50 cm (44.00” x 33.10” x 62.40”)
• 34 x 37 x 34 cm (13.5” x 14.5” x 13.5”)
iScan Coreo
iScan Coreo slide scanner | Digital Pathology

www.ventana.com | www.roche.com 55
56 Virtuoso image management software | Digital Pathology

Virtuoso
image management software
Our advanced digital pathology application software combines rich
functionality from slide viewing to case management. VENTANA
Virtuoso web-based software manages the digitised slide from scanning
to report. By combining intuitive functionality and a user-friendly
interface, this application improves the efficiency and productivity for
the pathologist. Virtuoso software and its role-based portals can be easily
adopted in your lab and will support multiple users in telepathology,
sharing and managing cases, viewing images and much more for use with
VENTANA slide scanners.
What’s on YOUR mind?
I need a way to review my cases remotely.
• Improve slide availability and portability with
digital archives
• Access cases remotely at any time, from anywhere, with
a web-based application
• View, manage and archive cases easily
I need a solution my entire lab can use effectively.
• Address the needs of each person in your workflow
with role-based portals
• Improve efficiency within the entire pathology
workflow process
I need to share my cases for peer reviews and tumour
boards.
• Share cases with one or more pathologists, with the
ability to set user-defined levels of access on a case
• Reduce turnaround time by sharing slides digitally
• Eliminate glass slide logistics
• Use collaboration sessions to share and view cases
simultaneously in different locations
www.ventana.com | www.roche.com 57
Digital Pathology | Virtuoso image management software

Specifications
Features
•
•
•
•
•
Quality control module allows the histotechnologist to review slide images prior to releasing them to the pathologist.
Side-by-side slide viewing and image synchronisation for simultaneous slide comparisons.
Intuitive user interface that mirrors pathology workflow allows users to re-arrange the order by which they view cases, specimens and images.
Availability of both a thick client and a true thin client option which eliminates the need to install software.
Customise each individual user’s permissions according to individual roles in your lab’s daily workflow.
Virtuoso Minimum System Requirements
Client operation system
• Windows XP SP2
Supported browsers
• Internet Explorer 7.0 or 8.0, Mozilla Firefox 3.6.13
RAM
• 2 GB
Network Connectivity
• 10/100 Mbps Ethernet network card
Other software requirements • Adobe Acrobat Reader 8.0 for generating reports in PDF
Physical Characteristics
Applied server specifications:
58 Operating system
• Windows 2008 SP2 64 bit
Processor
• Intel Dual Quad Core
RAM
• 16 GB
Network connectivity
• 1 GB Ethernet Network Card
Hard drive
• RAID 1/RAID 5 Configuration
• Hard Drives (2) 250 GB
• Hard Drives (3) 1 TB
Database
• MySQL 5.1 or Oracle v.11g Enterprise edition
Virtuoso image management software | Digital Pathology

www.ventana.com | www.roche.com 59
60 Customer Services |
Technical Consultation Centre 63
Education and Training 67
www.ventana.com | www.roche.com 61
62 Technical Consultation Centre | CUSTOMER SERVICES

Technical Consultation Centre
Our commitment is to provide world-class support in every interaction
with our customers. Our highly trained technical professionals offer
real-time access to technical and scientific assistance in native English,
French, German, Italian and Spanish to support any customer needs.
Our vision
Our priority is to provide prompt and accurate technical
support, assist our customers with information and
troubleshooting on VENTANA instruments, reagents and
software and create continual positive experiences that
result from timely and effective problem resolution. The
Technical Consultation Centre works in conjunction with
our Investigation and Applications Laboratory to receive
technical updates and perform product quality verification.
Our goal is to maintain a peerless Customer Support
Centre that meets and ultimately exceeds customers’
expectations.
Additional information, product images, package inserts
and material safety data sheets are now available online for
your viewing and printing convenience.
Visit our website at www.ventana.com or www.roche.com
and follow the links to our online product catalogue.
www.ventana.com | www.roche.com 63
CUSTOMER SERVICES | Technical Consultation Centre

Technical Support
How to contact us:
Monday to Friday: 8:00 am – 5:00 pm (CET and GMT)
EMEA fax: +33 (0)4 76 18 51 43
Germany fax: +49 (0)69 97 20 35 00
By phone:
Country
64 Toll Phone
Toll Free Phone Email
Austria
+33(0)476761820
Belgium
+33(0)476761822
[email protected]
Denmark
+33(0)476761826
[email protected]
Finland
+33(0)476761816
[email protected]
France
+33(0)476761818
[email protected]
Germany
+33(0)476761830
[email protected]
Italy
+33(0)476761832
Ireland
+33(0)476761817
[email protected]
Luxembourg
+33(0)476761818
[email protected]
Netherlands
+33(0)476761828
[email protected]
Northern Ireland
+33(0)476761817
Norway
+33(0)476761827
[email protected]
Poland (English)
+33(0)476761823
[email protected]
Portugal
+33(0)476761813
South Africa
+33(0)476761831
Spain
+33(0)476761812
Sweden
+33(0)476761829
Switzerland
+33(0)476761819
0800 80 66 80
[email protected]
United Kingdom
+33(0)476761817
0800 16 99 850
[email protected]
Other EMEA countries (ENGLISH)
+33(0)476761825
0 800 79 281
800 620 628
08007 833 119
800 200 299
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
902 112 476
[email protected]
[email protected]
[email protected]
www.ventana.com | www.roche.com 65
66 Education and Training | CUSTOMER SERVICES

Education and Training
Our Training Centre demonstrates our ongoing commitment to providing
complete customer support.
At our Education and Training Centre, we are committed
to making your training as enjoyable and informative as
possible.
Our objective is to provide you with the knowledge,
confidence, and resources to enable effective optimisation
of experimental conditions for faster research and to
increase the productivity of your laboratory.
Training programs, in small classes (maximum of 6
participants) conducive to efficient learning, are held
throughout the year at our comprehensive Training Centre
located at our European headquarters in Meylan (France). All
of our training courses are run by trainers highly experienced
in IHC or ISH techniques and in the VENTANA instruments
and reagents. We look forward to your visit in the near
futures, and trust you will enjoy our training experience.
www.ventana.com | www.roche.com 67
CUSTOMER SERVICES | Education and Training

Instrument User Training Courses
Training Name
Covered Topic
• Introduction to Roche Diagnostics
• NexES software presentation
• VENTANA products and reagents for DISCOVERY
and DISCOVERY XT platforms
• IHC and ISH runs
• Maintenance and decontamination
• Function tests
• Open discussion
DISCOVERY ULTRA induction
Catalogue reference
F-TRN-105200
• Presentation of the DISCOVERY ULTRA: features
and benefits
• Ventana System Software
• VENTANA products and reagents for DISCOVERY
ULTRA platform
• Maintenance and decontamination
• Function tests/Service tests
• IHC and ISH runs
• Open discussion
3,5 days
3389 € (w/o VAT)
68 Course Objectives
DISCOVERY / DISCOVERY XT induction The objective is that each attendee is able to
catalogue reference
use all of the capabilities of the instrument.
F-TRN-105000
The users will have a full presentation of
the instrument, software and both IHC and
ISH products. Protocol optimisation will be
3,5 days
approached, based on our strong experience,
to increase customer awareness of the main
3081 € (w/o VAT)
steps in effective experimental conditions, for
faster research and laboratory productivity
improvement.
The instrument maintenance and
decontamination will also be addressed during
the training.
The users will have a full presentation of the
instrument, the software and all the IHC and ISH
products.
The objective is that each attendant is able to
use the instrument with all its capabilities.
Protocol optimisation will be approached, based
on our strong experience, to increase customer
awareness of the main steps in effective
experimental conditions, for faster research and
laboratory productivity improvement.
Part of the training will be dedicated to the
instrument maintenance and decontamination
Education and Training | CUSTOMER SERVICES

www.ventana.com | www.roche.com 69
70 Appendix |
Index 72
www.ventana.com | www.roche.com 71
APPENDIX | Index
Index
A
A-1-Antichymotrypsin (ACT) 25
A-1-Antitrypsin (AAT) 25
AAT. See a-1-Antitrypsin (AAT) (polyclonal)
ACT. See a-1-Antichymotrypsin (ACT) (polyclonal)
ACTH 25. See Adrenocorticotropin (ACTH)
(polyclonal)
Actin, Muscle 25
Actin, Muscle Specific 25
Actin, Smooth Muscle 25
ALK1 25
Alpha-1-Fetoprotein (AFP) 25
Amplification 32
Amplification HQ Kit 32
Amplification Kit 32
Ancillary Reagents 32–43
Androgen Receptor 25
Annexin A1 25
Antibody Block 33
Antibody diluents 32
Antibody Dilution Buffer 32
Anti-HQ AP Multimer 32
Anti-HQ HRP Multimer 32
Application kits 33
B
Basal Cell Cocktail, VENTANA 25
BCA-225 25
bcl-2 25
bcl-6 25
Beta-Catenin 25
BG8 25
Biotinylated
Rabbit Secondary Antibody 33
Blockers 33
BlueMap Kit 21
Bluing Reagent 35
BOB.1 25
Bulk solutions 34
C
C3d 25
C4d 25
CA 19-9 25
CA 125 25
Calcitonin 25
Caldesmon 25
Calponin-1 25
72 Calretinin 25
CD1a 25
CD2 25
CD3 25
CD4 25
CD5 25
CD7 25
CD8 25
CD10, VENTANA 26
CD14 26
CD15 26
CD20 26
CD21 26
CD22 26
CD23 26
CD25 26
CD30 26
CD31 26
CD34 26
CD43 26
CD44 26
CD45 (LCA) 26
CD45R 26
CD45RO 26
CD56 26
CD57 26
CD61 26
CD63 26
CD68 26
CD71 26
CD79a 26
CD99 26
CD117. See PATHWAY c-KIT (CD117) (9.7)
CD138/syndecan-1 26
CD163 26
CDX-2 26
CEA 26. See Carcinoembryonic Antigen (CEA)
(TF3H8-1)
Chromogranin A 26
ChromoMap Blue 19
ChromoMap DAB 19
ChromoMap Red 19
Chromosome 3 DIG Probe 31
Chromosome 7 DIG Probe 31
Chromosome 7 Probe 31
Chromosome 8 DIG Probe 31
Chromosome 10 DIG Probe 31
Chromosome 15 DIG Probe 31
Chromosome 17 DIG Probe 31
Chromosome 17 Probe 31
c-KIT (CD117), PATHWAY 25
c-MET (Total), CONFIRM 25
c-Myc 25
Collagen Type IV 26
Counterstains 35
COX-2 (Cyclooxygenase 2) 26
Cyclin D1, VENTANA 26
Cyclooxygenase 2. See COX-2 (Cyclooxygenase 2)
(SP21)
Cytokeratin 26
Cytokeratin 5/6 27
Cytokeratin 7 27
Cytokeratin 8 27
Cytokeratin 8 & 18 27
Cytokeratin 10 27
Cytokeratin 14 27
Cytokeratin 17 27
Cytokeratin 19 27
Cytokeratin 20 27
Cytokeratin (CAM5.2) 26
Cytokeratin (HMW) 26
Cytokeratin (Pan) 26
D
DAB Map Kit 20
Desmin 27
Detection Chemistries 14–24
Discovery Amp HQ 22
DISCOVERY Amp HQ Kit 22
DISCOVERY Antibody Diluent 32
DISCOVERY anti-HQ Alk-Phos Multimer 22
DISCOVERY anti-HQ HRP Multimer 22
DISCOVERY Biotinylated Rabbit Secondary
Antibody 21
DISCOVERY Cell Conditioning 1 34
DISCOVERY EZ Prep 34
DISCOVERY ULTRA 7–9
Ordering information 9
Specifications 8
DISCOVERY Universal Secondary Antibody 21
DISCOVERY XT 11–13
Ordering information 13
Specifications 12
DOG1 27
E
E-Bar II slide label system 9, 13
E-Bar Label Kit 9, 13
E-Bar Mylar Shields 9, 13
E-Bar Printer Ribbon 9, 13
Labels 9, 13
EBER Probe 31
E-Cadherin, VENTANA 27
EGFR DNP Probe 31
Endogenous Biotin Blocking Kit 33
Enzymes 35
Ep-CAM/Epithelial Specific Antigen 27
Epidermal Growth Factor Receptor. See CONFIRM
EGFR (Epidermal Growth Factor Receptor)
(3C6); See CONFIRM EGFR (Epidermal
Growth Factor Receptor) (5B7)
Epithelial Growth Factor Receptor (EGFR) 27
Epithelial Membrane Antigen. See CONFIRM EMA
(Epithelial Membrane Antigen) (E29)
Epithelial Membrane Antigen (EMA) 27
Epithelial Related Antigen 27
ER. See CONFIRM Estrogen Receptor (ER) (SP1)
ERG 27
Estrogen Receptor (ER) 27
Index | APPENDIX
F
Factor VIII-R Ag 27
Factor XIIIa 27
Fascin 27
FGFR1 DNP Probe 31
Field Operations 67
FITC Albumin 30
FITC Antibodies 30
FITC C1q 30
FITC C3 30
FITC C4 30
FITC Fibrinogen 30
FITC IgA (Immunoglobulin A) 30
FITC IgG ( (Immunoglobulin G) 30
FITC IgM (Immunoglobulin M) 30
FITC Kappa 30
FITC Lambda 30
Follicle Stimulating Hormone. See FSH (Follicle
Stimulating Hormone) (polyclonal)
FSH (Follicle Stimulating Hormone) 27
G
Galectin-3 27
Gastrin 27
GCDFP-15 27
Glial Fibrillary Acidic Protein. See GRAP (Glial
Fibrillary Acidic Protein) (EP672Y)
Glial Fibrillary Acidic Protein (GFAP) 27
Glucagon 27
GLUT1 27
Glycophorin A 27
Glypican-3 27
Goat anti-Ms Alk-Phos Cocktail 19
Granzyme B 27
Growth Hormone (GH) 27
H
hCG. See Human Chorionic Gonadotropin (hCG)
(polyclonal)
hCG (Human Chorionic Gonadotropin) 27
Helicobacter Pylori, VENTANA 27
Hematoxylin 35
Hematoxylin II 35
Hepatocyte Specific Antigen. See HSA
(Hepatocyte Specific Antigen) (0CH1E5)
Hepatocyte Specific Antigen (HSA) 27
HER2 DNA Probe 31
HER2 Dual ISH DNA Probe CKTL 31
HER-2/neu, VENTANA 28
HER-2/neu, VENTANA 27
Herpes Simplex Virus I (HSV I) 28
Herpes Simplex Virus II (HSV II) 28
H&E staining 47
HGAL 28
hGH. See Human Growth Hormone (hGH)
(polyclonal)
HHV-8 (Human Herpes Virus Type 8) 28
hPL. See Human Placental Lactogen (hPL)
(polyclonal)
HPV II family 6 31
HPV III family 16 Probe 31
Human Herpes Virus Type 8. See HHV-8
(Human Herpes Virus Type 8) (13B10)
Human Placental Lactogen (hPL) 28
Hybridisation buffers 35
I
IgA (Immunoglobulin A) 28
IgD (Immunoglobulin D) 28
IGF1R DNP Probe 31
IgG4 28
IgG (Immunoglobulin G) 28
IgM (Immunoglobulin M) 28
Immunoglobulin A. See IgA (Immunoglobulin A)
(polyclonal)
Immunoglobulin G. See IgG (Immunoglobulin G)
(polyclonal)
Immunoglobulin M. See IgM (Immunoglobulin
M) (polyclonal)
Inhibin, alpha 28
INI-1 28
Insulin 28
Insulin Growth Factor-1 Receptor (IGF-1R) 28
iScan Coreo Au Slide Scanner 53–55
Specifications 54
K
Kappa 28
KAPPA Probe 31
Ki-67 28
Ksp-Cadherin 28
L
Lambda 28
LAMBDA Probe 31
LCA. See CONFIRM CD45 (LCA) (RP2/18);
See CD45 (LCA) (2B11 & PD7/26)
LH. See Luteinizing Hormone (LH) (polyclonal)
LH (Luteinizing Hormone) 28
Liquid Coverslip 34
LMO2 - Mouse 28
LMO2 - Rabbit 28
Lysozyme 28
M
Macrophage 28
Mammaglobin 28
MART-1/melan A 28
Melanoma Associated Antigen 28
Melanoma Triple Cocktail 28
Melanosome (HMB45) 28
Mesothelial Cell 28
MET DNA Probe 31
MITF 28
MLH-1 28
Molecular Probes 31
MoMap Kit 33
MSH2 28
MSH6 28
MUC1 28
MUC2 28
MUC5AC 28
MUC6 28
Multimer detection 15
MUM1 28
MYC DNP Probe 31
Myeloperoxidase (MPO) 28
Myogenin 28
Myoglobin 29
Myosin, Smooth Muscle 29
N
Napsin A 29
Negative Control Mouse Ig 29
Negative Control Rabbit Ig 29
Nerve Growth Factor Receptor (NGFR) 29
Neurofilament 29
Neuron Specific Enolase. See NSE (Neuron
Specific Enolase (E27)
O
Oct-2 29
Oct-4 29
OmniMap anti-Ms HRP 19
OmniMap anti-Rat HRP 19
OmniMap anti-Rb HRP 19
OmniMap DAB anti-Mouse (Ms) 18
OmniMap DAB anti-Rabbit (Rb) 18
OmniMap DAB anti-Rat 19
OmniMap Peroxidase Multimer detection
kits 18
P
p21WAF1 29
p27kip1 29
www.ventana.com | www.roche.com 73
APPENDIX | Index
p53 29
p57kip2 29
p63, VENTANA 29
p120 catenin, VENTANA 29
Pan. See Cytokertain (Pan) (AE1/AE3 & PCK26)
Parathyroid Hormone (PTH) 29
PAX-5 29
PAX8 29
Perforin 29
PGP 9.5 (Protein Gene Product 9.5) 29
PHH3 29
PIK3CA DNP Probe 31
PLAP. See Placental Alkaline Phosphatase (PLAP)
(NB10)
PLAP (Placental Alkaline Phosphatase) 29
PMS2 29
Podoplanin 29
Primary Antibodies 25–30
Progesterone Receptor (PR) 29
Programmed Death-1 (PD-1) 29
Prolactin 29
Prostate Specific Antigen. See CONFIRM (Prostate
Specific Antigen) (polyclonal); See PSA
(Prostate Specific Antigen) (ER-PR8)
Prostate Specific Antigen (PSA) 29, 30
Prostatic Acid Phosphatase. See PSAP (Prostatic
Acid Phosphatase) (PASE/4LJ)
Protease 1 35
Protease 2 35
Protease 3 35
PSAP (Placental Alkaline Phosphatase) 29
PSS Diluent 32
PTEN DNP Probe 31
PTH. See Parathyroid Hormone (PTH) (MRQ-31)
Q
QD DAPI 35
QD Map 605 SA-25 24
QD Map 655 SA-25 24
Quantum Dot Detection 24
R
RCC. See Renal Cell Carcinoma (RCC) (PN-15)
Reaction Buffer 34
Red Counterstain II 35
RedMap Kit 20
Renal Cell Carcinoma (RCC) 29
RiboCC 34
RiboHybe 35
RiboMap Kit 33
RiboWash 34
RUO antibodies 30
74 S
U
S100 29
S100P 29
S-Block 33
Secondary antibodies 21
Smoothelin 29
Somatostatin 29
SOX-2 29
Spectrin 29
Streptavidin-biotin detection 20
SV40 (Simian Virus-40) 29
SYMPHONY Clear 49
SYMPHONY fully automated H&E system 47–49
Ordering Information
OPTISURE Coverslips 49
SYMPHONY B 49
SYMPHONY C 49
SYMPHONY Clear 49
SYMPHONY D 49
SYMPHONY Desiccant Filter 49
SYMPHONY N1 49
SYMPHONY N2+ 49
SYMPHONY Staining System 49
SYMPHONY Tray Kit 49
SYMPHONY W 49
Specifications 48
Synaptophysin 29
Syndecan-1. See CD138 (Syndecan-1) (B-A38)
ULTRA LCS 34
UltraMap anti-Goat Hrp 19
UltraMap anti-Ms Alk- Phos 19
UltraMap anti-Ms Hrp 19
UltraMap anti-Rat Hrp 19
UltraMap anti-Rb Alk- Phos 19
UltraMap anti-Rb Hrp 19
UltraMap Blue anti-Ms 17
UltraMap Blue anti-Rb 18
UltraMap DAB anti-Ms 16
UltraMap DAB anti-Rat 16
UltraMap DAB anti-Rb 16
UltraMap Goat anti-Rb 19
UltraMap Multimer Detection Kit 16
UltraMap Red anti-Ms 17
UltraMap Red anti-Rb 17
Universal Secondary Antibody 33
Uroplakin III 30
User-fillable dispensers 36
V
Villin 30
Vimentin 30
Virtuoso image management software 57–59
Specifications 58
T
TAG-72 30
Tartrate-Resistant Acid Phosphatase. See TRAcP
(Tartrate-Resistant Acid Phosphatase) (9C5)
T-bet 29
TdT (Terminal Deoxynucleotidyl Transferase) 30
Terminal Deoxynucleotidyl Transferase. See TdT
(Terminal Deoxynucleotidyl Transferase)
(polyclonal)
TFE3 30
Thymidine Phosphorylase (TP) 30
Thyroglobulin 30
Thyroid Transcription Factor-1 (TTF-1) 30
TOP2A DNP Probe 31
Topoisomerase 30
TRAcP (Tartrate-Resistant Acid Phosphatase) 30
Tryptase 30
TSH. See Thyroid Stimulating Hormone (TSH)
(polyclonal)
TTF-1. See CONFIRM Thyroid Transcription Factor-1
(TTF-1) (8G7G3/1)
Tyrosinase 30
W
WT1 30
Z
ZAP-70 30
Roche Diagnostics International Ltd.
CH-6343 Rotkreuz
Switzerland
www.roche.com
www.ventana.com
© 2013 Ventana Medical Systems, Inc.
and Roche Diagnostics International Ltd.
VENTANA, the VENTANA logo, CONFIRM,
DISCOVERY, INFORM, iScan, Optisure,
PATHWAY, RiboMap, SYMPHONY and
VIRTUOSO are trademarks of Roche.
All other trademarks are the property of their
respective owners.
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