INFORMATIONAL MEMORANDUM ISSUE: AVIAN INFLUENZA IMPORTANCE: Avian Influenza (AI) is a highly contagious disease that can devastate poultry flocks, disrupt trade and in certain circumstances cause human illness. The industry would suffer sever economic losses if an outbreak occurred in the U.S. BACKGROUND: AI or "Bird Flu" is a highly contagious viral infection that has been detected in at least 60 species of wild birds. It can manifest itself in different ways depending mainly on the pathogenicity of the virus involved and on the species affected. Influenza infections in birds are divided in two groups on the basis of their ability to cause disease. Highly Pathogenic AI (HPAI) is a serious disease that can result in bird mortality up to 100 percent. HPAI viruses spread throughout he infected birds, including into meat tissues, and will be both inside and outside eggs from infected hens. HPAI is a reportable disease to the World Animal Health Organization (OIE). Most AI strains are classified as Low Pathogenic AI (LPAI); LPAI is generally a mild disease and is reportable if caused by H5 or H7 viruses. The LPAI virus may mutate into HPAI virus; but the two infections will be distinct. Wild birds, and especially waterfowls, are usually naturally resistant and generally are asymptomatic. Exposure of domestic poultry to feces of infected migratory waterfowl and the international movement of live poultry pose risks for introducing AI into U.S. poultry. Once introduced, the disease can be spread from bird to bird by direct contact, manure, equipment, vehicles, egg flats, crates, and people whose clothing or shoes have come in contact with the virus. AI viruses can remain viable at moderate temperatures for long periods in the environment and can survive indefinitely in frozen material. However, the viruses are susceptible to typical sanitizing agents. LPAI poses no known serious threat to human health. However, human infections with specific strains of HPAI viruses may be fatal. Since December 2003, a growing number of countries have reported outbreaks of HPAI in chickens and ducks. Humans also have been infected, most of who had direct contact with infected birds. Therefore, preventative measures are needed to avoid new AI outbreaks and eradicate outbreaks as soon as possible. Experts take the view that an influenza pandemic affecting humans is inevitable and may be imminent. Animal husbandry systems where humans live in close cohabitation with poultry are considered the most likely source of new strains capable of crossing the species barrier from animal to man, through genetic reassortment or recombination. The OIE and the Food and Agricultural Organization (FAO) of the United Nations maintain rapid alert and notification systems on animal health and food safety that cover influenza. 98 Informational Memorandum Avian Influenza Page 2 of 2 AMI partnered with the National Restaurant Association to sponsor an AI symposium in Washington, D.C. on January 12 and 13, 2006, and presented a webinar on AI to AMI members on June 6, 2006. An AI technical paper written by AMI Vice President for Regulatory Affairs is posted on the AMI website; the most recent update is November 22, 2006. STATUS: Since 2003, the particularly virulent H5N1 highly pathogenic strain of the disease has caused the death or destruction of over 200 million birds and the death of at least 153 people in Azerbaijan, Cambodia, China, Egypt, Indonesia, Iraq, Thailand, Turkey and Viet Nam. The HPAI H5N1 virus has been detected in at least 58 countries. Avian flu is still endemic in the affected countries and eradication is proving extremely difficult; and the disease continues to spread along the waterfowl flyway patterns. Furthermore, there are fears that this particular virus strain may eventually lead to a human flu pandemic and involve swine as an intermediary or additional host. In November 2005, Agriculture Secretary Mike Johanns requested $91 million in additional funding to help safeguard the U.S. against HPAI. The additional funding will be used to increase surveillance, improve biosecurity of poultry farms, control movement of birds that could spread the disease, enhance international efforts on risk mitigation, ensure disposal programs are adequate and environmentally sound, and educate producers and consumers at home and abroad. The funding also would be used to produce an additional 40 million doses of vaccines against H5 and H7 viruses to be used in the event of outbreaks in U.S. poultry operations. The USDA published its National Strategic Plan for Avian Influenza (dated January 2006) in March 2006. Several countries, including the U.S., have imposed trade restrictions on birds and raw poultry products to protect animal health. OIE and WHO state that any poultry products destined for human consumption from countries experiencing outbreaks of AI do not pose a risk to public health. Cooked poultry products from areas with H5N1 outbreaks can be imported into the U.S. as long as all regulatory requirements are met. The World Health Organization (WHO), the FAO and the OIE have called for decisive action by governments to help the affected countries control bird flu outbreaks and thereby reduce the potential public health risks. AMI POSITION: AMI will continue to monitor AI and its impact on poultry operations, assist the federal government and other trade associations to minimize the impact of the disease on the industry, and assist members in planning for business continuity in the event of a pandemic associated with AI. AMI CONTACTS: JAMES HODGES PRESIDENT AMI FOUNDATION SKIP SEWARD VICE PRESIDENT AMI – REGULATORY AFFAIRS JANUARY 2007 99
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