NITROBENZENE
NITROBENZENE
ICSC: 0065
Peer-Review Status: 06.04.2006 Validated
CAS #: 98-95-3 RTECS #:
DA6475000
UN #: 1662
EC #: 609-003-00-7
EINECS #: 202-716-0
Formula: C6H5NO2
Molecular mass: 123.1
TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS
FIRE
Combustible. Gives off irritating or toxic
fumes (or gases) in a fire.
NO open flames.
Use water spray, alcohol-resistant
foam, dry powder, carbon dioxide.
Above 88°C explosive vapour/air
Above 88°C use a closed
In case of fire: keep drums, etc.,
cool by spraying with water.
PREVENTION
EXPLOSION mixtures may be formed. Risk of fire and system and ventilation.
FIRST AID / FIRE-FIGHTING
explosion. See Chemical Dangers.
AVOID ALL CONTACT!
IN ALL CASES CONSULT A
DOCTOR!
Headache. Blue lips, fingernails and
skin. Blue lips, fingernails and skin.
Dizziness. Nausea. Weakness.
Confusion. Convulsions.
Unconsciousness.
Use ventilation, local exhaust or
breathing protection.
Fresh air, rest. Artificial respiration
may be needed. Refer for medical
attention.
MAY BE ABSORBED! Further see
Inhalation.
Protective gloves. Protective
clothing.
Remove contaminated clothes.
Rinse and then wash skin with
water and soap. Refer for medical
attention .
Wear safety goggles.
First rinse with plenty of water for
several minutes (remove contact
lenses if easily possible), then refer
for medical attention.
Do not eat, drink, or smoke
during work.
Rinse mouth. Give a slurry of
activated charcoal in water to drink.
Rest. Refer for medical attention .
EXPOSURE
Inhalation
Skin
Eyes
See Inhalation.
Ingestion
SPILLAGE DISPOSAL
Personal protection: complete protective clothing including selfcontained breathing apparatus. Do NOT let this chemical enter
the environment. Collect leaking and spilled liquid in sealable
containers as far as possible. Absorb remaining liquid in sand or
inert absorbent. Then store and dispose of according to local
regulations.
PACKAGING & LABELLING
Do not transport with food and feedstuffs.
EC Classification
Symbol: T, N; R: 23/24/25-40-48/23/24-51/53-62; S: (1/2)-2836/37-45-61
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II
GHS Classification
Signal: Danger
Harmful if swallowed
Toxic if inhaled (vapour)
Toxic in contact with skin
Suspected of causing cancer
Suspected of damaging fertility or the unborn child
May cause damage to blood cells
Harmful to aquatic life with long lasting effects
EMERGENCY RESPONSE
SAFE STORAGE
Transport Emergency Card: TEC (R)-61S1662 or 61GT1-II.
NFPA Code: H3; F2; R1.
Separated from combustible substances, reducing agents,
strong oxidants, strong acids and food and feedstuffs. Store in
an area without drain or sewer access.
IMPORTANT DATA
Physical State; Appearance
PALE YELLOW OILY LIQUID WITH CHARACTERISTIC
ODOUR.
Routes of exposure
The substance can be absorbed into the body by inhalation,
through the skin and by ingestion.
Physical dangers
Inhalation risk
A harmful contamination of the air will be reached rather slowly
on evaporation of this substance at 20°C; on spraying or
dispersing, however, much faster.
Chemical dangers
On combustion, forms toxic and corrosive fumes including
nitrogen oxides. Reacts violently with strong oxidants and
reducing agents. This generates fire and explosion hazard.
Reacts violently with strong acids and nitrogen oxides. This
generates explosion hazard.
Effects of short-term exposure
The substance may cause effects on the blood. This may result
in formation of methaemoglobin. Exposure could cause lowering
of consciousness. The effects may be delayed. Medical
observation is indicated.
Occupational exposure limits
TLV: 1ppm as TWA; (skin); A3 (confirmed animal carcinogen
with unknown relevance to humans); BEI issued; (ACGIH 2005).
MAK: Carcinogen category: 3B; Skin absorption (H); BAT
issued; (DFG 2006).
EU OEL ( selected): 0.2ppm, 1mg/m³ as TWA;.
Effects of long-term or repeated exposure
The substance may have effects on the blood, spleen and liver.
This substance is possibly carcinogenic to humans. Animal tests
show that this substance possibly causes toxicity to human
reproduction or development.
PHYSICAL PROPERTIES
ENVIRONMENTAL DATA
Boiling point: 211°C
Melting point: 5°C
Relative density (water = 1): 1.2
Solubility in water, g/100ml: 0.2
Vapour pressure, Pa at 20°C: 20
Relative vapour density (air = 1): 4.2
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 88°C c.c.
Auto-ignition temperature: 480°C
Explosive limits, vol% in air: 1.8-40
Octanol/water partition coefficient as log Pow: 1.86
The substance is harmful to aquatic organisms. It is strongly
advised not to let the chemical enter into the environment.
NOTES
Use of alcoholic beverages enhances the harmful effect.
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Do NOT take working clothes home.
Card has been partly updated in October 2006: see sections Occupational Exposure Limits.
Card has been partially updated in January 2008: see GHS classification.
ADDITIONAL INFORMATION
IPCS
International
Programme on
Chemical Safety
LEGAL NOTICE
Prepared in the context of cooperation between the International Programme on Chemical Safety
and the European Commission
© IPCS 2004-2012
Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.