Department of Physiology Physiology Moderatorship Junior Sophister Handbook 2015–2016
Table of Contents:
Introduction to the
Department of Physiology
Welcome to the Department of Physiology, 2nd Floor,
TBSI, 152-160 Pearse Street.
Staff and contact details of the
Department of Physiology
Physiology staff are based in TBSI, Watts Building and
TCIN (Lloyd building).
Term Dates: 2015-2016
MT: 31st August– 18th December
Teaching term commences 28th September
HT: 18th January – 8th April
Physiology Module Structure
55 ECTS of compulsory courses and 5 ECTS for an
optional course.
Physiology Modules
Module codes , module coordinator, course
descriptions, key reading, timetables by module.
Administrative Matters
Academic Matters
Examination
Examination Structure
Introduction
Welcome to the Department of Physiology! It is our aim to help you to have an enjoyable and
rewarding learning experience for the next 2 years. The fact that you are in a small class in a relatively
small department means that you will soon get to know everyone and feel part of the Department.
The purpose of this Handbook is to give you valuable information about the Department and your
courses. Additional information is available on the Department website. Courses in the Department
cover a range of systems from the subcellular to the body as a whole. The courses are demanding and
you will need to develop existing skills and acquire new ones. We expect students to work hard and to
take responsibility for their learning. The course credit system specifically allows for time to be set aside
for revision preparation of assignments etc. to allow students to perform to the best of their ability. At
the same time it places the onus for private study on the individual student. About 50% of the year’s
marks are allocated to in-course assessments.
We also expect to provide help to students while they are actively acquiring new skills and new
knowledge, so you should not hesitate to discuss matters with the relevant member of staff. Any student
who needs supports because of a disability should contact Dr Áine Kelly, the Department’s contact
person for disability support. Matters related to specific courses will be best dealt with by consulting the
member of staff responsible for the course. Most other matters should be brought to the attention of the
Course Adviser. Only if these channels fail should you normally go to the Head of Discipline. From time to
time you will be asked to take part in evaluation of your courses as part of our efforts to monitor and
improve our courses. Such evaluations are confidential and have no connection to student assessment;
students are asked to treat them seriously.
We wish you every success over the next two years.
Dr. Alice Witney, Physiology Moderatorship Course Advisor, 2015
Department of Physiology Staff Teaching on the Physiology Moderatorship:
All of these staff can be contacted by direct email (for list see website) or via the Departmental Office ([email protected])
Departmental Executive Officer: Ms. Christine Monahan (extension 2723), 2nd Floor, TBSI
Teaching Staff
Dr Alice Witney
Dr Áine Kelly
College Title
Assistant Professor in
Physiology
Head of Discipline
Associate Professor in
Physiology
Building
Initial
[email protected] TBSI
AW
[email protected] TBSI
AK
TBSI
DE
TBSI
AM
Dr Deirdre Edge
Assistant Professor in
Physiology
[email protected] Dr Aedín Minogue
Assistant Professor in
Neuroscience
[email protected] Dr Eric Downer
Assistant Professor in
Physiology
[email protected] TBSI
ED
Prof Veronica Campbell
Professor in Physiology
[email protected] TBSI
VC
Prof Kumlesh Dev
Professor in Neuroscience
[email protected] TBSI
KKD
Dr Mikel Egana
Assistant Professor in
Physiology
[email protected] Watts
ME
Mr Bernard Donne
Senior Experimental Officer
[email protected] Watts
BD
Dr Joel Rocha
Research Fellow
[email protected] Watts
JR
Prof Maeve Caldwell
Professor in Neuroscience
[email protected] TCIN
MC
Prof Marina Lynch
Professor of Cellular
Neuroscience
[email protected] TCIN
MAL
Dr Pat Hartigan
Emeritus Fellow
Teaching Staff Office Locations: TBSI, Watts, TCIN
Contact Details –
email
[email protected] PJH
Technical Staff
College Title
Contact Details
Building
Mr. Quentin Comerford
Experimental Officer
[email protected]
TBSI
Ext 2550
[email protected]
TBSI
Senior Technical Stores
Ext 1170
[email protected]
Watts
Chief Technical Officer 1
Ext 1392
[email protected]
Watts
Mr. David Fletcher
Ms. Alice Jordan
Mr. Kieran Walsh:
Mr. Aidan Kelly
Dr Noreen Boyle
Chief Technical Officer
(Specialist)
Chief Technical Officer
(Specialist)
Senior Technical Officer
Ext 1555
[email protected]
Ext 1351
[email protected]
TBSI Teaching
Lab L2.20
TBSI Teaching
Lab L2.20
Ext 1351
Physiology Moderatorship Learning Outcomes
By the end of this course students will have:
1. Studied all systems of the human body, including the nervous, musculoskeletal, gastrointestinal,
immune, endocrine, reproductive, cardiovascular and respiratory systems, in both lecture and
practical settings.
2. Developed research skills including practical laboratory skills, critical analysis of published
journal articles and statistical analysis of data
3. Applied their knowledge of physiology to discuss case studies and general problems in
physiology in an integrated manner
4. Completed a full-time, individual original research project in an aspect of physiology, have
written-up this project according to the standards of the Journal of Physiology and presented the
results to their peers and academic staff in oral form.
Junior Sophister
Module Breakdown and
Assessment
MODULE CODE
MODULE NAME
ECTS
Marks In-course
Marks total
% of year
PG3000
Research Skills
5
50
50
8.33
PG3050
Intro/PDP/Library & computer
skills
10
10
1.66
PG3960
Data Handling
20
20
3.33
Writing & Research Skills
10
10
1.66
PG3125
Concepts and Problems
10
10
1.66
PG3135
Nerve, muscle and sensation
5
50
50
8.33
PG3110
Tissue structure
5
50
50
8.33
PG3980
Journal club
5
50
50
8.33
PG3700
Gut, Metabolism and
hormones
5
50
50
8.33
PG3600
Endocrine Regulation
16
16
2.66
PG3070
Gut, Kidney and Hormones
34
34
5.66
PG3950
Seminars in pharmacological
& physiological research
52
48
100
16.67
PG3100
Cell Physiology
14
16
30
5.00
PG3400
Physiological Pharmacology
8
32
40
6.67
PG3900
Seminars + Ethics
30
30
5.00
PG3300
Physiology of Brain, Nerve
and Muscle
45
50
8.33
PG3301
Sensory
11.25
11.25
1.88
PG3302
Brain
22.5
22.5
3.75
PG3303
Muscle & Nerve
5
11.25
16.25
1.88
PG3200
Fluids, Heat and Metabolism
15
35
50
8.33
PG3500
Cardiovascular Physiology
16
50
64
10.67
PG3800
Respiratory Physiology
10
24
36
6
298
252
550
91.67
49.7
42.0
Total
% of year (group 3 is 8.3%)
1 credit=10 marks
10
5
5
5
5
55
5
Marks exam
PG3000:
Research Skills
Dr Áine Kelly
5 ECTS Credits
Course Personnel: Dr Áine Kelly, Dr Alice Witney, Mr Bernard Donne, Ms Lorna Flannery,
Ms Sarah Jones, Mr Peter Nowlan
Module Aim:
The purpose of this module is to develop core research skills necessary for successful completion of the
Physiology moderatorship. It incorporates the following elements:
PG3050
Introduction
This course serves as a general introduction to the course and includes library training and a Personal
Development Programme (PDP), run by the Careers Advisory Service, which reviews, highlights and
develops transferable skills.
Lecture (MT)
Lecture Date
Location
Lecturer and Topic
MT1 (5), Monday
28th September
L2.20, TBSI
Introduction
10 – 11 am
MT1 (5), Thursday
Dr Alice Witney
1st October
3 – 5 pm
MT1 (5), Tuesday
29th September
10 – 11 am
MT 12 (16), Wednesday
16th December
Berkeley Library
Library Services
South Training Room
Ms Lorna Flannery
Physiology Department
Photographs
2nd Floor TBSI
Mr Quentin Comerford
L2.15
SS Physiology Design
Presentations
9 am – 5 pm
Lecture (HT)
Lecture Date
Location
Lecturer and Topic
HT 1 (21), Friday
22nd January
Watts Seminar Room
Careers Advisory (CAS)
10 am – 12 pm
HT 2 (22), Friday
Ms Sarah Jones
29th January
Watts Seminar Room
10 am – 12 pm
HT 4 (24), Friday
Careers Advisory (CAS)
Ms Sarah Jones
12th February
Watts Seminar Room
10 am – 12 pm
CV Clinic & CAS
Assessment
Ms Sarah Jones
HT 5 (25), Friday
19th February
Watts Seminar Room
10 am – 12 pm
CV Clinic & CAS
Assessment
Ms Sarah Jones
HT 12 (32), Tuesday
9 am – 5 pm
5th April
L2.15
SS Physiology Research
Presentations
Please note that all students are expected to attend the following event:
Physiological Society GL Brown Prize Lecture.
The speaker is Prof. Mike Tipton, University of Portsmouth and his lecture is entitled “Extreme
Threats”.
MT 2 (6), Wednesday
7th October
6pm (wine reception to follow)
Paccar Theater,
Science Gallery
Extreme Threats
Speaker: Prof. Mike Tipton
In this lecture, Prof. Tipton will discuss human physiological responses to extreme environments.
This topic exemplifies both fundamental and applied physiology and illustrates the core principle of our
discipline: homeostasis. As such, it is a perfect primer on integrative physiology.
Each student will need to register at the following webpage:
https://dublin.sciencegallery.com/events/2015/09/extremethreatsmiketipton
Events and information days:
Health Sector Jobs Expo, 10th October 2015
Venue: Clyde Court Hotel, Dublin
Come and meet with Employers both from home and abroad, seeking Nurses, Midwives, Doctors,
Dentists and Allied Health Professionals all under the one roof.
To Register for Free Entry visit: www.HealthSectorJobs.com/Dublin
Frontiers in Neurology (FIN5) 5th Annual Meeting
Friday 20th November 2015
Venue: Trinity Institute of Biosciences (TBSI), Pearse Street, Dublin Trinity College Dublin
To Register for Free Entry visit: www.neurologyireland.com
PG3125:
Concepts & Problems
Dr Áine Kelly
Course Aim: to instruct students in basic concepts applicable to multiple physiological systems and to
ensure knowledge of core concepts in physics and chemistry that relate to physiology.
Assessment: In-course.
Lecture
Lecture Date
Location
Lecturer and Topic
MT 1 (5), Monday
12 – 1 pm
28th September
Watts Seminar Room
Dr Áine Kelly
MT 1 (5), Wednesday
12 – 1 pm
30th September
Watts Seminar Room
Dr Áine Kelly
MT 2 (6), Monday
12 – 1 pm
5th October
Watts Seminar Room
Dr Áine Kelly
MT 2 (6), Wednesday
12 – 1 pm
7th October
Watts Seminar Room
Dr Áine Kelly
MT 3 (7), Monday
12 – 1 pm
12th October
Watts Seminar Room
Dr Áine Kelly
MT 3 (7), Wednesday
12 – 1 pm
14th October
Watts Seminar Room
Dr Áine Kelly
MT 4 (8), Monday
12 – 1 pm
19th October
Watts Seminar Room
Dr Áine Kelly
MT 4 (8), Wednesday
12 – 1 pm
21st October
Watts Seminar Room
Dr Áine Kelly
PG3960:
Data Handling & Writing Research Skills
Dr Áine Kelly
Aim: The purpose of this course is to review the most common statistical tests used in biological
research and the concepts underlying them.
Assessment: Practical exercises in-course.
Lecture
Lecture Date
Location
Lecturer and Topic
MT 3 (7), Tuesday
13th October
Berkley Library
Endnote Training
2 – 4 pm
MT 4 (8), Tuesday
South Training Room
20th October
Watts Seminar Room
2 – 4 pm
MT 5 (9), Tuesday
Dr Áine Kelly
27th October
Watts Seminar Room
2 – 3 pm
MT 11 (15), Monday
7th December
Watts Seminar Room
1st February
LB11
8th February
LB11
11th February
LB11
9th February
EE.PC2
EE.PC3
3 – 5 pm
15th February
EE.PC2
Data Handling
Prof Maeve Caldwell
16th February
EE.PC2
2 – 4 pm
HT 5 (25), Wednesday 17th February
Data Handling
Prof Maeve Caldwell
3 – 5 pm
11 am – 1 pm
Data Handling
Prof Maeve Caldwell
HT 4 (24), Wednesday 10th February
HT 5 (25), Tuesday
Data Handling
Prof Maeve Caldwell
2 – 4 pm
HT 5 (25), Monday
Data Handling
Prof Maeve Caldwell
11 am – 1 pm
HT 4 (24), Tuesday
Data Handling
Prof Maeve Caldwell
9 – 11 am
HT 4 (24), Thursday
Animal Handling
Peter Nowlan
3 – 5 pm
HT 4 (24), Monday
Writing & Research Skills
Dr Áine Kelly
2 – 5 pm
HT 4 (23), Monday
Writing & Research Skills
Data Handling
Prof Maeve Caldwell
EE.PC2
Data Handling
Prof Maeve Caldwell
PG3000: Research Skills
Module Learning Outcome
On successful completion of this course the student will:
1. Be familiar with the services offered by the Careers Library and the College Library and have
completed training in use of the Library databases.
2. Have conducted a skills audit and identified the transferable skills developed to date, new skills
that should be acquired and existing skills that require further development.
3. Have completed a job study report.
4. Be familiar with the following concepts: the influence of the chemical structure of water on cell
and systems physiology; mechanisms of transport in physiological systems; the relationship
between pressure, volume and flow (with specific reference to Boyle’s ideal gas Law, Poiseuille’s
Law and LaPlace’s Law); acid-base balance; regulation of metabolism.
5. Have researched a case study in physiology and, with classmates, prepared and delivered an oral
presentation of the same.
6. Understand the concepts underlying the use of statistical tests including t-tests, regression
analysis and analysis of variance, and understand their application.
7. Have knowledge of the following practical research skills: record-keeping, care of laboratory
animals, making up of solutions, dilutions and assays, calibration of equipment, calibration logs,
report writing.
PG3110:
Cell and Tissue Structure
Term taught: MT
Lecture (Shared with Med
students)
MT 1(5), Monday
2 – 3 pm
Professor Maeve Caldwell
5 ECTS Credits
Lecture Date
Location
Lecturer and Topic
28th September
L2.15
(TERCEN)
Epithelial Tissue
Prof Maeve Caldwell
MT 1 (5), Wednesday
9 – 10 am
MT 1 (5), Thursday
9 – 10 am
30th September
L2.15
1st October
B1.15
(SQ)
Excitable Cells: Muscle
Prof Maeve Caldwell
Excitable Cells: Nervous System
Prof Maeve Caldwell
MT 2 (6), Monday
9-10am
MT 2 (6), Monday
2 – 3 pm
MT 8 (12), Thursday
9 – 10 am
MT 9 (13), Monday
9 – 10 am
MT 9 (13), Monday
2 – 3 pm
5th October
L2.15
5th October
L2.15
19th November
B1.15
23rd November
L2.15
23rd November
L2.15
Labs PG3110
Lecture Date
Location
Lecturer and Topic
MT 2 (6), Tuesday
10 am – 1 pm
MT 3 (7), Tuesday
10 am – 1 pm
MT 4 (8), Tuesday
10 am – 1 pm
MT 5 (9), Tuesday
10 am – 1 pm
6th October
L2.20
13th October
L2.20
20th October
L2.20
27th October
L2.20
MT 6 (10), Tuesday
10 am -1 pm
MT 8 (12), Friday
10 am – 1 pm
MT 9 (13), Friday
10 am – 1 pm
3rd November
L2.20
20th November
L2.20
27th November
L2.20
LAB1: Digital SlideBox Lab 1
Prof Maeve Caldwell
LAB2: Digital SlideBox Lab 2
Prof Maeve Caldwell
LAB3: Histology
Prof Maeve Caldwell
LAB4: Immunocytochem
(LAB COATS)
Prof Maeve Caldwell
LAB5: Confocal Imaging
Prof Maeve Caldwell
LAB6: Haematology
Prof Maeve Caldwell
LAB7: In-course Assessment
Prof Maeve Caldwell
Connective Tissue: General
Prof Maeve Caldwell
Connective Tissue: Bone
Prof Maeve Caldwell
Blood I
Prof Maeve Caldwell
Blood II
Prof Maeve Caldwell
Thermoregulation
Prof Maeve Caldwell
Module Learning Aims:
1. Demonstrate knowledge of the components of tissues and how they work together in organ
function
2. Explain some pathophysiological examples from a variety of tissues and organs
3. Interpret two-dimensional images as three-dimensional structures.
4. Give examples of changes in tissue structure in relation to function; physiological,
pathophysiological and developmental states.
5. Explain the basis of the classification of tissues according to different criteria.
6. Comment on the value of different types of classification and show an appreciation of the
historical development of the bases of classification of tissues.
7. Able to examine, interpret and comment upon a variety of tissues using the light microscope;
including preparation artifacts and staining.
Module learning outcomes:
1. Interpret two-dimensional images as three-dimensional structures.
2. Relate structure to function.
3. Give examples of changes in tissue structure in relation to function
4. Physiological, pathophysiological and developmental states.
5. Explain the basis of the classification of tissues according to different criteria.
6. Comment on the value of different types of classification.
7. Show an appreciation of the historical development of the bases of classification of tissues.
Reading List:
- Young, B & Heath, JW (2006). Wheater’s Functional Histology — A Text and
Colour Atlas 5th edn. London: Churchill Livingstone.
– Sherwood (2009). Human Physiology from Cells to Systems. Thomson
Assessment Details: In-course examination
PG3135:
Nerve, Muscle and Sensation
Dr Alice Witney
5 ECTS Credits
These six practical classes examine the following aspects of (mainly human) nerve muscle function:
•
•
•
•
Amphibian nerve (using simulation
software).
Human nerve/muscle.
Reflex and reaction times.
Thermal pain thresholds.
•
•
•
•
Visual fields and blind spot.
Limb proprioception.
Audiometry.
Visual and haptic illusions.
The labs introduce you to psychophysical methods, electromyogram (EMG) recording and nerve
stimulation.
In tutorials you discuss background literature, experimental design and presentation of experimental
data.
Assessment: 100% In-course assessment. Includes: Practical write-ups; Tutorial participation.
Nerve Muscle and Sensation Schedule:
Labs
Lab Date
Location
Lecturer and Topic
MT 1 (5), Thursday
10 am – 12 pm
MT 2 (6), Thursday
9 am – 12 pm
MT 3 (7), Thursday
10 am – 1 pm
MT 4 (8), Thursday
10 am – 1 pm
MT 5 (9), Thursday
10 am – 1 pm
MT 6 (10), Thursday,
9 am – 12 pm
1st October
L2.20
8th October
L2.20
15th October
L2.20
22nd October
L2.20
29th October
L2.20
5th November
L2.20
Frog Nerve
Dr Alice Witney
EMG
Dr Alice Witney
Sensation & Rotations
Dr Alice Witney
Rotations
Dr Alice Witney
Rotations
Dr Alice Witney
Rotations
Dr Alice Witney
Tutorial
Tutorial Date
Location
Lecturer and Topic
MT 1 (5), Wednesday,
10 – 11 am
MT 2 (6), Wednesday,
10 – 11 am
MT 3 (7), Wednesday,
10 – 11 am
MT 4 (8), Wednesday,
10 – 11 am
MT 5 (9), Wednesday,
10 – 11 am
30th September
L2.20
Dr Alice Witney
7th October
B2.36
14th October
B1.06
21st October
B1.06
28th October
B1.06
Frog Nerve
Dr Alice Witney
Sensory Thresholds
Dr Alice Witney
Scientific Abstracts
Dr Alice Witney
Overall Assessment
Dr Alice Witney
The aim of this course is to introduce students to the careful conducting of scientific experiments, along
with the collection and handling of results and writing of scientific reports.
On successful completion of this course the student will:
1.
Be able to conduct scientific experiment in a meaningful way.
2.
Be able to collect and process data collected from these experiments.
3.
Know how to write a comprehensive laboratory report.
4.
Understand the details of human skeletal muscle and nerve function.
5.
Have carried out simple tests on the human visual, auditory and proprioception systems.
6.
To have knowledge of human reflex and reaction times and influencing factors.
PG3950:
Seminars in Physiological and Pharmacological Research
10 ECTS Credits
This course incorporates the following elements:
•
PART I: PG3100 Cell Physiology
Professor Marina Lynch
Topics include:
o Membrane structure,.
o Membrane proteins.
o Membrane properties.
o Receptors.
o Neurotransmitters — definition and
release.
Assessment: Oral presentation and assessment; report write-up; examination.
•
PART II: PG3400 Physiological Pharmacology
Kumlesh Dev
Dr Deirdre Edge & Prof
Topics include:
Basic principles of drug action.
Pharmacodynamics.
Pharmacokinetics.
The effect of drugs on chemical
transmission.
o Autonomic.
o
o
o
o
o
o
o
o
o
o
Pharmacology.
Cardiovascular pharmacology.
Drug toxicity.
Immunopharmacology.
Gene-based therapy.
Neuropharmacology.
Assessment: Oral presentation of a pharmacological topic; examination.
•
PART III: PG3900 Seminars
Topics include: Ethical and Philosophical issues.
Assessment: In-course assessment.
Dr Alice Witney
PG3100 Cell Physiology
Professor Marina Lynch
Lecture
Lecture Date
Location
Lecturer and Topic
MT 1 (5), Monday
28th September
LTEE2
Lipid Membrane
3 – 5 pm
MT 1 (5), Tuesday
Professor Marina Lynch
29th September
LB11
11 am – 1 pm
MT 1 (5), Wednesday
11 am – 12 pm
30 September
MT 1 (5), Thursday
1 October
th
st
LB11
Professor Marina Lynch
Calcium I
LTEE2
Professor Marina Lynch
Calcium II
2 – 3 pm
MT 2 (6), Monday
Dr Karen Bryson
5th October
LTEE2
3 – 4 pm
Receptor Signalling
Professor Marina Lynch
MT 2 (6), Wednesday
11 am – 12 pm
7th October
MT 2 (6), Thursday
8 October
th
LB11
Neurotransmitters I
LTEE2
Professor Marina Lynch
Neurotransmitters II
2 – 3 pm
MT 3 (7), Monday
Reactive Oxygen Species and
Age related changes to the lipid
membrane
Professor Marina Lynch
12th October
LTEE2
3 - 4 pm
Neurotransmitters III
Professor Marina Lynch
MT 3 (7), Wednesday
11 – 12 pm
14th October
MT 3 (7), Thursday
15 October
th
LB11
Plasma Membrane Proteins I
LB11
Professor Marina Lynch
Plasma Membrane Proteins II
2 – 3 pm
Professor Marina Lynch
PG3100
Tutorials/ Problem-Based Learning:
Lecture
Lecture Date
Location
Lecturer and Topic
MT 4 (8), Tuesday
20th October
Watts Seminar Room
Professor Marina Lynch
26th November
Watts Seminar Room
Professor Marina Lynch
9 – 10 am
MT 9 (13), Thursday
2 – 5 pm
PG3400:
Physiological Pharmacology
Dr Deirdre Edge & Prof Kumlesh Dev
Topics include:
Basic principles of drug action.
Pharmacodynamics.
Pharmacokinetics.
The effect of drugs on chemical
transmission.
o Autonomic pharmacology.
o
o
o
o
o
o
o
o
o
Cardiovascular pharmacology.
Drug toxicity.
Immunopharmacology.
Gene-based therapy.
Neuropharmacology.
Assessment: Oral presentation of a pharmacological topic; examination.
Schedule
Lecture
Lecture Date
Location
Lecturer and Topic
HT 1 (21) Tuesday
19th January
Watts Seminar Room
Prof Kumlesh Dev
20th January
Watts Seminar Room
Dr Deirdre Edge
26th January
Watts Seminar Room
Prof Kumlesh Dev
2nd February
Watts Seminar Room
Dr Deirdre Edge
9th February
Watts Seminar Room
Dr Deirdre Edge
10th February
Watts Seminar Room
Dr Deirdre Edge
10 am – 1 pm
HT 1 (21) Wednesday
11 am – 1pm
HT 2 (22) Tuesday
10 am – 1 pm
HT 3 (23) Tuesday
10 am – 12 pm
HT 4 (24) Tuesday
11 am – 1 pm
HT 4 (24) Wednesday
11 am – 1 pm
PG3900:
Seminars
Dr Alice Witney
This special programme of seminars will cover a wide range of material designed to enhance students’
understanding of Science in general and Physiology in particular.
Assessment: In course assessment
Lecture
Lecture Date
Location
Lecturer and Topic
HT 5 (25), Tuesday
16th February
Watts Seminar room
Dr Alice Witney
23rd February
Watts Seminar room
Dr Áine Kelly
1st March
Watts Seminar room
Dr Deirdre Edge
8th March
Watts Seminar room
Prof Marina Lynch
15th March
Watts Seminar room
Dr Alice Witney
10 am – 1 pm
HT 6 (26), Tuesday
10 am – 1 pm
HT 7 (27), Tuesday
10 am – 1 pm
HT 8 (28), Tuesday
10 am – 1 pm
HT 9 (29),Tuesday
10 am – 1 pm
PG3700:
Gut, Metabolism and Hormones
Dr Mikel Egana
5 ECTS Credits
Term taught: MT and HT
PART I: Endocrine Regulation (PG3600)
Dr Mikel Egana
PART II: Physiology of Gut, Kidney and Hormones (PG3070)
Prof Maeve Caldwell,
Dr Eric Downer,
Dr Deirdre Edge.
PG3600 Endocrine Regulation
Course Lecturers: Dr Patrick Hartigan; Dr Mikel Egana; Dr Joel Rocha
The course deals with:
o The role of the endocrine system in the regulation of metabolic.
o Excretory and reproductive processes in mammals, with particular emphasis on the co-operative
activities of the endocrine.
o Neural systems in the physiological responses of the organism to a variety of stressors, including
those that arise during athletic endeavours.
The main focus is on structure-function adaptations in target organs and cells and on the influence of
environmental conditions on the control of energy, water, ions and acid-base balance.
Assessment: Examination
Students: Physiology; Molecular Medicine and Exercise Physiology
Reading List: Sherwood, Human Physiology
Course Schedule: PG3600
Lecture
Lecture Date
Location
Lecturer and Topic
MT 8 (12), Thursday
19th November
Watts Seminar Room
Introduction to Endocrinology
11 am – 12 pm
MT 8 (12), Thursday
Dr Pat Hartigan
19th November
Watts Seminar Room
12 – 1 pm
MT9 (13), Thursday
GIT & Pancreas
Dr Pat Hartigan
26th November
Watts Seminar Room
11 am – 12 pm
Hypothalamus – Pituitary –
Peripheral glands
Dr Pat Hartigan
MT9 (13), Thursday
26th November
Watts Seminar Room
12 – 1pm
MT10 (14), Thursday
Dr Pat Hartigan
3rd December
Watts Seminar Room
10 – 11am
MT10 (14), Thursday
3rd December
Watts Seminar Room
10th December
Watts Seminar Room
Appetite control I
Dr Joel Rocha
10th December
Watts Seminar Room
10 – 11 am
MT 13 (17), Thursday
Introduction to metabolism
Dr Pat Hartigan
9 am – 10 am
MT 12 (16), Thursday
Renal Regulation
Dr Pat Hartigan
11am – 12pm
MT 12 (16), Thursday
Adrenal glands
Appetite control II
Dr Joel Rocha
17th December
Watts Seminar Room
10 am – 11 am
Regulation of reproductive
hormones I
Dr Mikel Egana
MT 13 (17), Thursday
11 am – 12 pm
17th December
Watts Seminar Room
Regulation of reproductive
hormones II
Dr Mikel Egana
Lecture Synopses
Lecture 1:
Introduction to Endocrinology (PH, 19-11-15, 11:00)
•
Discussion of the lecture series and what is to follow.
•
Hydrophilic and lipophilic hormones.
•
Basic intro on endocrine glands - different types/locations/structures etc.
Lecture 2:
GIT & Pancreas (PH, 19-11-15, 12:00)
•
Contrast “classical” endocrine system with diffuse system.
•
Endocrine pancrease & exocrine pancreas.
•
Glucose regulation: insulin, glucagon, somatostatin.
•
Local GIT hormones: gastrin, CCK, somatostatin.
•
Interaction between ingesta and gut hormones and between products of digestion and
endocrine pancreas.
Lecture 3:
Hypothalamus – Pituitary – Peripheral glands (PH, 26-11-15, 11:00)
•
Structural relationship.
•
Feedback:
o Paracrine – endocrine.
o Negative – positive.
•
Importance of pulsatility.
•
Posterior pituitary: oxitocin, ADH.
Lecture 4:
Adrenal glands (PH, 26-11-15, 12:00)
Structural features:
o Cortex, medulla, vasculature.
o Interactions between cortex and medulla.
o Endocrine and neural aspects.
•
Glucocorticoids.
•
Mineralocorticoids.
•
Catecholamines.
Lecture 5:
Renal Regulation (PH, 3-12-15, 10:00)
•
Structural aspects relevant to action of hormones.
•
Regulation of fluid balance and blood pressure.
•
Erithropoietin.
Lecture 6:
Introduction to metabolism (PH, 3-12-15, 11:00)
Lecture 7:
Appetite control I (JR, 10-12-15, 9:00)
Lecture 8:
Appetite control II (JR, 10-12-15, 10:00)
Lecture 9:
Regulation of reproductive hormones I (ME, 17-12-15, 10:00)
•
Male regulation.
•
Female regulation.
•
Cycle descriptions.
Lecture 10:
Regulation of reproductive hormones II (ME, 17-12-15, 11:00)
•
Exercise in pregnancy.
•
The female athlete triad.
Endocrine Regulation Learning Outcomes :
When they have completed this module students should be able to:
•
•
•
•
•
•
•
•
•
•
Differentiate different types of hormones and endocrine glands.
Describe the interactions between ingesta and gut hormones.
Describe the interactions between products of digestion and the endocrine pancreas.
Distinguish and outline the structural and functional relationships between the hypothalamus,
pituitary, and peripheral glands.
Distinguish and outline the structural and functional features of the adrenal, thyroid, and
parathyroid glands.
Identify the mechanisms responsible for the hormonal regulation of fluid balance and blood
pressure.
Describe the hormonal regulation of male and female reproduction.
Describe the physiological control of appetite.
Describe the acute and chronic effects of exercise on appetite control.
Describe the benefits and risks of exercising during pregnancy.
PG3700 Gut, Metabolism and Hormones (PART II)
PG3070 Physiology of gut, kidney, and hormones (Prof Maeve Caldwell; Dr Eric Downer; Dr
Deirdre Edge)
This lecture course is shared with 1st year Medicine, Human Form and Function.
The course covers:
o Gut function.
o Metabolism.
o Renal function
o Growth, including the
hypothalamic/pituitary axis.
o Reproduction: regulation of gender, the
ovarian cycle, pregnancy and
parturition.
Course Schedule: PG3070
Lectures
Lecture Date
Location
Lecturer and Topic
26th November
B1.15
Endocrine I – Endocrine System
(SQ)
Prof Maeve Caldwell
L2.15
Endocrine II – Pituitary, Hypothalamus
Shared with Meds
MT 9 (13), Thursday
9 – 10 am
MT 10 (14), Monday
30th November
9 – 10 am
MT 10 (14), Monday
Prof Maeve Caldwell
30th November
L2.15
10 – 11 am
MT 10(14), Monday
Prof Maeve Caldwell
30th November
L2.15
2 – 3 pm
MT 10(14), Thursday
3rd December
7th March
B1.15
Endocrine V – Endocrine control of Calcium
(SQ)
Prof Maeve Caldwell
L2.15
The Gastrointestinal Tract
9 – 10 am
HT 8(28), Wednesday
Dr Eric Downer
9th March
L2.15
9 – 10 am
HT 8 (28), Thursday
9 – 10 am
Endocrine IV – The Pancreas & Insulin
Prof Maeve Caldwell
9 – 10 am
HT 8(28), Monday
Endocrine III – Endocrine control of Growth
Gastric Secretion & Motility
Dr Eric Downer
10th March
L2.15
Physiology of the Small Intestine
Dr Eric Downer
Lectures
Lecture Date
Location
Lecturer and Topic
14th March
L2.15
The Liver and Pancreas
PG3070
HT 9 (29), Monday
9 – 10 am
HT 9 (29), Wednesday
Dr Eric Downer
16th March
L2.15
9 – 10 am
HT 10 (30), Monday
Dr Eric Downer
21st March
L2.15
9 – 10 am
HT 10(30), Wednesday
23rd March
L2.15
24th March
HT 11 (31), Wednesday
9 – 10 am
30th March
HT 11 (31), Thursday
31st March
B1.15
Water & Salt balance
(SQ)
Dr Deirdre Edge
L2.15
Acid-base balance
Dr Deirdre Edge
9 – 10 am
4th April
B1.15
Renal System – Clinical scenarios
(SQ)
Dr Deirdre Edge
L2.15
Endocrine Regulation of gender
9 – 10 am
Dr Deirdre Edge
HT 12 (32), Wednesday
9 – 10 am
6th April
HT 12 (32), Thursday
6th April
L2.15
9 – 10 am
Male/female reproductive systems
Dr Deirdre Edge
L2.15
10 - 11 am
HT 12 (32), Thursday
Reabsorption and Micturition
Dr Deirdre Edge
9 – 10 am
HT 12 (32), Monday
Organization of the Renal System
Dr Deirdre Edge
9 – 10 am
HT 10 (30), Thursday
The Large Intestine
Menstral cycle & fertilization
Dr Deirdre Edge
7th April
B1.15
Parturition and lactation
(SQ)
Dr Deirdre Edge
Gut, Kidney and Hormones Learning Outcomes:
By the end of this unit, students will be able to:
1. Outline the structure and function of the digestive tract, liver and pancreas.
2. Describe the regulation of motility and secretion.
3. Describe the digestion and absorption of carbohydrate, proteins and fats.
4. Explain pathophysiological examples of fat and carbohydrate metabolism (Including coeliac
disease and diabetes mellitus.
5. Describe the structures and functions of the human kidneys and urinary tract.
6. Demonstrate understanding of the homeostatic roles sustained by the kidneys.
7. Use knowledge of the phenomena and mechanisms occurring in the kidneys and urinary tract to
explain the performance of their homeostatic functions and to predict the principal
consequences of renal failure of various origins.
8. Demonstrate an understanding of the fundamental structure of the endocrine system.
9. Describe the specialized functions of endocrine glands and tissues, including mechanisms of
feedback regulation.
10. Define the principal actions of the classical hormones and their regulated release mechanisms .
11. Understand the relevance of hormone action to integrated whole body metabolism.
12. Describe the structure and function of the male and female reproductive organs.
13. Understand the endocrinology of birth, puberty and pregnancy.
14. Apply their physiological knowledge to understanding the pathogenesis and natural history of
common clinical endocrine disorders.
Reading List: Sherwood, Human Physiology
Assessment: Examination
PG3300:
Physiology of Brain, Nerve and Muscle
Dr Alice Witney
5 ECTS Credits
Taught: MT and HT
Lecturers: Prof Marina Lynch; Dr Áine Kelly; Dr Aedín Minogue; Dr Alice Witney.
This course incorporates the following elements
PG 3301:
Muscle and Nerve
Dr Aedín Minogue
Learning Aims:
The principal aims of this module are:
(i)
(ii)
(iii)
(iv)
To introduce the concept of excitable cells.
To understand the sequence of cellular events, which lead to contraction of skeletal
muscle.
To explore the structure and mechanical properties of skeletal muscle
To understand how the neuromuscular system adapts in relation to specific exercise and
clinical cases.
Module content:
1.
Cellular generation of membrane potentials and action potentials.
2.
Action potential conduction and neuromuscular transmission.
3.
Skeletal muscle structures and mechanics.
4.
Force production via excitation-contraction coupling and the cross-bridge cycle.
5.
Characteristics of motor units and their recruitment.
6.
Fibretypes.
7.
Reflexes.
Learning Outcomes:
On successful completion of the module, the students will:
1.
Understand some of the electrical properties of excitable cells and the ordered cellular events
required for cell to cell (or neuromuscular) transmission.
2.
Have an in depth understanding of the mechanics and structures of skeletal muscle critical to
production and maintenance of force.
3.
Understand how muscle function may be compromised both clinically and during exercise, and
in contrast how this decline in function may be improved.
Lecture
Lecture Date
Location
Lecturer and Topic
1st October
Watts Seminar Room
Membrane Biology &
Action Potential
PG3301
MT 1 (5), Thursday
12 – 1 pm
Dr Aedín Minogue
MT 2 (6), Wednesday
7th October
Watts Seminar Room
9 – 10 am
MT 2 (6), Thursday
Neurons, Nerves
Dr Aedín Minogue
8th October
Watts Seminar Room
12 - 1pm
Skeletal Muscle:
Extension/ Contraction
Dr Aedín Minogue
MT 3 (7), Monday
12th October
Watts Seminar Room
11 am – 12 pm
MT 4 (8), Wednesday
Dr Aedín Minogue
21st October
Watts Seminar Room
9 – 10 am
MT 4 (8), Friday
23rd October
Watts Seminar Room
28th October
Watts Seminar Room
29th October
Watts Seminar Room
4th November
Watts Seminar Room
Reflexes
Dr Alice Witney
5th November
Watts Seminar Room
12 – 1 pm
Assessment: In course assessment and examination
Rate Code
Dr Alice Witney
9 – 10 am
MT 6 (10), Thursday
Motor Unit Recruitment
Dr Alice Witney
9 – 10 am
MT 6 (10), Wednesday
Muscle Fibretypes
Dr Alice Witney
9 – 10 am
MT 5 (9), Thursday
Assessment
Dr Aedín Minogue
9 – 10 am
MT 5 (9), Wednesday
Cross Bridge
Assessment
Dr Alice Witney
PG3302:
Sensory Physiology
Dr Áine Kelly, Prof Marina Lynch
This set of lectures is an introductory course to synaptic transmission and sensory physiology. The basic
properties of sensory processing are covered and details the physiological properties of the following
senses:
1. Somatosensory - including non-nociceptive and nociceptive skin sense organs, and also
proprioceptors especially muscle spindle organs.
2. Visual - the functioning of the eye.
3. Hearing - the functioning of the cochlea.
4. Balance - the functioning of the semicircular canals and the otolith organs.
5. Taste and smell.
Module Outcomes:
1. To have a knowledge of the basic common features of the physiological processing of sensory stimuli.
2. To have a knowledge of the physiological functioning of the major sense organs
Sensory Physiology
Lecture
Lecture Date
Location
Lecturer and Topic
MT 3 (7), Monday
12th October
L2.15
CNS Organisation
(TERCEN)
Dr Áine Kelly
L2.15
Action potentials
9 – 10 am
MT 3 (7), Monday
12th October
2 – 3 pm
MT 3 (7), Wednesday
Dr Áine Kelly
14th October
L2.15
9 – 10 am
MT 3 (7), Thursday
Dr Áine Kelly
15th October
9 – 10 am
MT 4 (8), Monday
19th October
B1.15
Neurotransmission II
(SQ)
Dr Áine Kelly
L2.15
Sensory Perception
9 – 10 am
MT 4 (8), Monday
Prof Marina Lynch
19th October
L2.15
2 – 3 pm
MT 4 (8), Thursday
22nd October
B1.15
The Eye
Prof Marina Lynch
29th October
2 – 3 pm
Assessment: Examination
Somatic Sensory System
Prof Marina Lynch
9 – 10 am
MT 5 (9), Thursday
Neurotransmission I
L2.15
The Ear
Prof Marina Lynch
PG3303:
Brain
Dr Aedín Minogue
Module Content:
This module of 18 lectures covers the following topics:
1.
Properties and physiological functions of ionic channels, including Na, K, Ca and Cl channels.
2.
Properties and physiological functions of transmitter receptors including ionotropic and
metabotropic receptors.
3.
Introduction to brain functioning.
4.
Processing of sensory information in the brain, especially somatosensory and visual information.
5.
Properties of motor areas of the brain, including pre-motor cortical areas, motor cortex, basal
ganglia and cerebellum.
6.
Memory mechanisms of the brain.
7.
Key features of other brain functions, including plasticity of brain functioning, sleep, oscillatory
properties of the brain, reward and addiction, mirror neurons, the default network, prefrontal
cortex and decision making, neuroeconomics, brain-machine interfaces and consciousness.
Lecture (with 2nd Med)
Lecture Date
Location
Lecturer and Topic
HT 1 (21), Monday
18th January
B1.15
Neurotransmitters, ion channels & synaptic
transmission I
2 – 3 pm
(SQ)
Dr Aedín Minogue
HT 1 (21), Wednesday
20th January
B1.15
10 - 11 am
Neurotransmitters, ion channels & synaptic
transmission II
Dr Aedín Minogue
HT 1 (21), Friday
22nd January
B1.15
12 – 1 pm
Neurotransmitters, ion channels & synaptic
transmission III
Dr Aedín Minogue
HT 2 (22), Monday
25th January
B1.15
2 – 3 pm
HT 2 (22), Wednesday
Dr Aedín Minogue
27th January
B1.15
10 – 11 am
HT 2 (22), Friday
12 – 1 pm
Electrophysiological Techniques I
Electrophysiological Techniques II
Dr Aedín Minogue
29th January
B1.15
Electrophysiological Techniques III
Dr Aedín Minogue
Lecture
Lecture Date
Location
Lecturer and Topic
HT 3 (23), Monday
1st February
B1.15
The Visual System I
2 – 3 pm
HT 3 (23), Wednesday
Dr Aedín Minogue
3rd February
B1.15
10 – 11 am
HT 4 (24), Friday
Dr Aedín Minogue
5th February
B1.15
2 – 3 pm
HT 5 (25), Wednesday
10th February
B1.15
12th February
B1.15
15th February
B1.15
17th February
B1.15
The Motor System II
Dr Aedín Minogue
19th February
B1.15
12 – 1 pm
HT 7 (27), Monday
The Motor System I
Dr Aedín Minogue
10 – 11 am
HT 6 (26), Friday
The Somatosensory System II
Dr Aedín Minogue
2 – 3 pm
HT 6 (26), Wednesday
The Somatosensory System I
Dr Aedín Minogue
12 – 1 pm
HT 6 (26), Monday
The Visual System III
Dr Aedín Minogue
10 – 11 am
HT 5 (25), Friday
The Visual System II
The Motor System III
Dr Aedín Minogue
22nd February
B1.15
2 – 3 pm
Learning & Memory, Rewards Circuits &
Addiction I
Dr Aedín Minogue
HT 7 (27), Wednesday
24th February
B1.15
10 – 11 am
Learning & Memory, Rewards Circuits &
Addiction II
Dr Aedín Minogue
HT 7 (27), Friday
12 – 1 pm
26th February
B1.15
Learning & Memory, Rewards Circuits &
Addiction III
Dr Aedín Minogue
Learning Outcomes:
On successful completion of the course, the students will:
1. Have a detailed knowledge of ionic channel functioning.
2. Have an understanding of how the brain processes sensory information.
3. Have an understanding of how the brain programmes movement.
4. Have an advanced knowledge of the general principles of brain functioning, especially
modern concepts of how the brain functions as a parallel processing and adaptable
computer.
PG3500:
Cardio Vascular
Dr Áine Kelly
5 ECTS Credits
Module Content and Aims:
The lecture sequence will examine the functioning and regulation of the circulatory system, using the
themes of adaptive responses to exercise and environmental change. Students will be assumed to be
already familiar with the basic principles of cardiovascular structure and functions.
Topics will include:
o
o
o
o
o
o
o
Cardiac excitation and function.
Haemodynamics.
Pressure and flow measurement.
Vascular architecture.
Foetal development of the heart.
Control of regional resistance.
Water movement between bloodstream
and tissues.
o Reflex control of blood pressure.
o Forebrain pathways in cardiovascular
regulation.
o Pulmonary perfusion.
o High blood pressure (hypertension).
o Effects of training.
o Circulatory adaptations to pregnancy.
o Syncope and shock.
Some teaching sessions will be devoted to analysis of case histories illustrating typical scenarios of
cardiovascular adaptation or abnormality.
Lectures
Lecture Date
Location
Lecturer and Topic
HT 4 (24), Wednesday
2 – 3 pm
10th February
Watts Seminar room
Dr Áine Kelly
HT 5 (25), Thursday
12 – 1 pm
HT 6 (26), Wednesday
12 – 1 pm
18th February
Watts Seminar room
Dr Áine Kelly
24th February
Watts Seminar room
Dr Áine Kelly
HT 6 (26), Thursday
12 – 1 pm
HT 7 (27), Wednesday
12 – 1 pm
25th February
Watts Seminar room
Dr Áine Kelly
2nd March
Watts Seminar room
Dr Áine Kelly
HT 7 (27), Thursday
12 – 1 pm
HT 8 (28), Wednesday
12 – 1 pm
HT 8 (28), Thursday
12 – 1 pm
3rd March
Watts Seminar room
Dr Áine Kelly
9th March
Watts Seminar room
Dr Áine Kelly
10th March
Watts Seminar room
Dr Áine Kelly
HT 9 (29), Wednesday
12 – 1 pm
HT 10 (30), Thursday
12 – 1 pm
HT 11 (31), Thursday
12 – 1 pm
HT 12 (32), Thursday
12 – 1 pm
16th March
Watts Seminar room
Dr Áine Kelly
24th March
Watts Seminar room
Dr Áine Kelly
31st March
Watts Seminar room
Dr Áine Kelly
7th April
Watts Seminar room
Dr Áine Kelly
Cardiovascular laboratory classes will give insights into techniques for quantifying cardiovascular
performance and allow students to plan and carry through a short research project using these
techniques.
Labs PG3500
Lab Date
Location
Lecturer and Topic
HT4 (24), Thursday
11th February
L2.20
Dr Heather Reilly
2 – 5 pm
HT 5 (25), Thursday
Dr Áine Kelly
18th February
L2.20
25th February
L 2.20
3rd March
L 2.20
10th March
L 2.20
14th March
L 2.20
24th March
L 2.20
31st March
L 2.20
7th April
L 2.20
2 – 5 pm
HT 6 (26), Thursday
2 – 5 pm
HT 7 (27), Thursday
2 – 5 pm
HT 8 (28), Thursday
2 – 5 pm
HT 9 (29), Monday
2 – 5 pm
HT 10 (30), Thursday
2 – 5 pm
HT 11 (31), Thursday
2 – 5 pm
HT 12 (32), Thursday
2 – 5 pm
Assessment: Group project (including some peer assessment) and reports; Examination.
References: Useful texts include the following.
West — Best & Taylor's Physiological Basis of Medical Practice (Williams & Wilkins)
Berne & Levy — Cardiovascular Physiology (Mosby)
Guyton & Hall — Textbook of Medical Physiology (Saunders)
Plowman & Smith — Exercise Physiology for Health and Fitness (Prentice Hall)
McArdle, Katch & Katch — Exercise Physiology (Williams & Wilkins)
PG3200:
Fluid Heat and Metabolism
Dr Mikel Egana
5 ECTS Credits
Module Content and Aims:
This course deals with the regulation of temperature, metabolism and fluids, and particularly how this
occurs during thermal stress and exercise.
A key focus is on learning basic aspects of regulation, and then applying this learning to interpreting
human responses measured in the laboratory.
This learning is fostered through short lectures, tutorials and laboratory experiments, as well as through
the preparation of a visual and written presentation about a topic of interest to the student.
Lectures
Lecture Date
Location
Lecturer and Topic
HT 1 (21), Thursday
10 – 11 am
21st January
Watts Seminar room
Introduction
Dr Mikel Egana
HT 1 (21), Thursday
11 am – 12 pm
21st January
Watts Seminar room
Heat balance equation
Dr Mikel Egana
HT 2 (22), Thursday
10 – 11 am
28th January
Watts Seminar room
Heat loss
Dr Mikel Egana
HT 2 (22), Thursday
11 am – 12 pm
28th January
Watts Seminar room
Energy systems
Dr Mikel Egana
HT 2 (22), Thursday
12 pm – 1 pm
28th January
Watts Seminar room
Sweating
Dr Mikel Egana
HT 3 (23), Thursday
10 – 11 am
4th February
Watts Seminar room
Exercise in the cold
Dr Mikel Egana
HT 3 (23), Thursday
11 am – 12 pm
4th February
Watts Seminar room
Exercise & dehydration
Dr Mikel Egana
HT 3 (23), Thursday
12 pm – 1 pm
4th February
Watts Seminar room
Exercise in the heat
Dr Mikel Egana
HT 4 (24), Thursday
10 – 11 am
11th February
Watts Seminar room
Student presentations I
Dr Mikel Egana
HT 5 (25), Thursday
10 – 11 am
18th February
Watts Seminar room
Student presentations II
Dr Mikel Egana
HT 5 (25), Thursday
11 am – 12 pm
18th February
Watts Seminar room
Student presentations III
Dr Mikel Egana
PG3200 Laboratory classes:
Labs
Tutorial Date
Location
Lecturer and Topic
HT 1 (21), Wednesday
20th January
L2.20
Measurement of oxygen uptake
2 – 5 pm
HT 3 (23), Wednesday
Dr Mikel Egana
3rd February
L2.20
2-5pm
HT 5 (25), Wednesday
2-5pm
Experiment 1: ice immersion
Dr Mikel Egana
17th February
L2.20
Experiment 2: Exercise &
thermoregulation
Dr Mikel Egana
Assessment: Written report, lab report, oral presentation, examination
PG3980:
Journal Club Schedule
Dr Alice Witney
5 ECTS Credits
Module content and aims: Seminars giving an opportunity to study individual scientific articles and to
acquire the necessary skills for evaluating them. Students may be required to make short, informal
presentations.
Lecture
Lecture Date
Location
Lecturer and Topic
HT 3 (23), Monday
1st February
Watts Seminar Room
Dr Alice Witney
8th February
Watts Seminar Room
Dr Alice Witney
15th February
Watts Seminar Room
Mr Bernard Donne
22nd February
Watts Seminar Room
Mr Bernard Donne
29th February
Watts Seminar Room
Prof Marina Lynch
7th March
Watts Seminar Room
Prof Marina Lynch
14th March
Watts Seminar Room
Mr Bernard Donne
29th March
Watts Seminar Room
Assessment
10 am – 12 pm
HT 4 (24), Monday
11 am – 1 pm
HT 5 (25), Monday
10 am – 12 pm
HT 6 (26), Monday
10 am – 12 pm
HT 7 (27), Monday
11 am – 12 pm
HT 8 (28), Monday
11 am – 12 pm
HT 9 (29), Monday
10 am – 12 pm
HT 11 (31), Tuesday
10 am – 1 pm
Assessment: In-course.
Dr Alice Witney
PG3800: Respiratory Physiology Dr Mikel Egana
Module content:
o Respiratory mechanics.
o Lung compliance & airway resistance.
o Diffusion.
o Transport of O2.
o Transport of CO2.
Practical classes explore:
o Spirometry & lung volumes.
o Respiratory gas analysis & dead space
o Role of respiration in blood acid/base
homeostasis.
o Control of ventilation.
o Respiration in altered environments
o Ventilation/ perfusion with exercise.
o Exercise & acid/base status.
Lectures
Lecture Date
Location
Lecturer and Topic
HT 1 (21), Monday
18th January
L2.15
The respiratory System
9 – 10 am
HT 1 (21), Wednesday
Dr Mikel Egana
20th January
L2.15
9 – 10 am
HT 1 (21), Thursday
Dr Mikel Egana
21st January
B1.15
9 – 10 am
HT 2 (22), Monday
25th January
L2.15
Gas exchange
Dr Mikel Egana
27th January
L2.15
9 – 10 am
HT 2 (22), Wednesday
Ventilation
Dr Mikel Egana
9 – 10 am
HT 2(22), Wednesday
Lung Mechanics
Gas transport
Dr Mikel Egana
27th January
Watts Seminar Room
12 – 1 pm
Inspiratory muscle training – VO2
kinetics
Dr Mikel Egana
HT 2 (22), Thursday
28th January
B1.15
9 – 10 am
HT 3 (23), Monday
9 – 10 am
Respiratory control
Dr Mikel Egana
1st February
L2.15
Effects of barometric pressure
Dr Mikel Egana
Lectures
Lecture Date
Location
Lecturer and Topic
HT 3 (23), Wednesday
3rd February
B1.15
Effects of exercise
9 – 10 am
HT 3 (23), Wednesday
Dr Mikel Egana
3rd February
Watts Seminar Room
12 – 1 pm
HT 2 (21), Thursday
Limits of maximal exercise tolerance
Dr Mikel Egana
Tutorial Date
Location
Lecturer and Topic
21st January
L2.20
Spirometry & Douglas bags
2 – 5 pm
HT 3 (22), Thursday
Dr Mikel Egana
28th January
L2.20
2 – 5 pm
HT 3 (22), Thursday
Research project
Dr Mikel Egana
4th February
L2.20
2 – 5 pm
Research project
Dr Mikel Egana
Assessment: Weekly practical assessment/poster; examination.
Reference: West — Best & Taylor's Physiological Basis of Medical Practice (Williams & Wilkins)
Optional Modules:
Either
Comparative Physiology Dr P Wilson/ Dr M Wride
ECTS Credits: 5 [Physiology students can take this as a Group III option]
This course uses comparative examples drawn from throughout the animal kingdom to illustrate general
principles of animal physiology. The concept of form and function presented in the SF course
('Vertebrate Form and Function') is developed further in the present course, which focuses on the
mechanisms underlying the movements of animals. Topics to be covered include: amoeboid and ciliary
movement; muscle contraction; circulatory systems; respiratory pigments; gas exchange; energetics and
the environment. The emphasis is on the integration of cellular process into the system, but relevant
features of particularly important molecules, such as the respiratory pigments and contractile proteins,
will also be discussed.
Timetable: Two lectures per week in Michaelmas Term; Two laboratory classes.
Assessment: Examination
Reference: Eckert, Roger, et al. (1997). Animal Physiology: Mechanisms and Adaptations Fourth edition.
WH Freeman & Company ISBN 0716724146 Hamilton Library 591.1 M81*3 S-LEN 591.1 M81*3 (4 copies)
Or
Broad Curriculum 2015/16
It is part of College’s education strategy that all students should be given the opportunity to experience
knowledge and ideas outside their main subject area as Group III courses. Broad Curriculum courses
consist of 5 credits spread over the Michaelmas and Hilary terms. Details of the BC courses, including
timetables can be found at http://www.tcd.ie/Broad_Curriculum. Broad Curriculum courses are
assessed as Group III courses, i.e. they count towards the overall JS mark.
Administrative Matters
Data Protection/Confidentiality: Various kinds of information about students are retained in the
Department. This consists mainly of contact information and progress data (results of assessments and
examinations). Files are available for inspection by subjects. This information will not be disclosed to
third parties (other than College staff who have a demonstrated legitimate need, e.g. marks to Faculty
Office) without express permission from the subject.
Department Library/Photocopying: The Department has holdings of several standard textbooks
and key journals. Removal of books and journals from the rooms in which they are shelved is not
permitted (except for photocopying). Material to be photocopied must be left in Ms Christine Monahan ’s
office with a completed copy of the Copying Request Form. Students’ attention is drawn to copyright
restrictions: all material must be for private study and not more than 10% of any book or more than one
article from an issue of a journal should be copied.
Personal References: Members of staff are usually willing to act as referees. However, it is an
important courtesy that each individual is asked before giving his/her name as a referee. If s/he is has not
given permission, s/he could properly refuse to provide a reference. Please allow adequate time for
references to be prepared. Adequate time is at least two weeks.
Lost Property: Property left in teaching laboratories will be retained in those laboratories. Property left
elsewhere will be stored in Mr Kieran Walsh’s office. Items clearly bearing a name will be returned to the
owner. Lost property is normally disposed of after the end of the academic year.
Safety and Security: Information can be provided by Mr Kieran Walsh
IT support: Please consult Mr Quentin Comerford.
Academic Matters
Academic Commitment
We expect all students to attend all classes, especially practical classes. The standard College
procedures of production of medical certificates for absences of more than a few days applies OR if the
absence means a deadline or an assessment will be missed. Medical certificates may be submitted via
the College Tutor or directly to the Course Adviser. Absence for other important reasons should also be
notified to the Course Adviser, either directly or via the College Tutor. It is helpful if a student who knows
s/he is going to be absent notifies the Course Adviser. Explanations of absence are essential for
examinations and when deadlines are likely to be missed. Requests for extensions of deadlines should
be processed via College Tutor or directly to the Course Adviser. Details of medical certificates and other
personal information will be treated confidentially.
The Department operates the College procedure in relation to ‘Non-satisfactory attendance and course
work’ (Calendar). That is, any student who misses more than a third of a course in any term or fails to
complete assignments may be declared ‘non-satisfactory’. Non-satisfactory returns are made to the
Senior Lecturer; such students may be refused permission to take the annual examination and may be
required by the Senior Lecturer to repeat the year.
Assessments
Every effort has been made to ensure the accuracy of this information but it may be necessary to
make changes from time to time. Students will be informed of changes as soon as possible.
In-Course Assessments
In-course assessment in Physiology accounts for a large % of the year. The nature of the assessments is
given in the summary of each course. Individual members of teaching staff will give more details at the
beginning of each course. Meeting deadlines is regarded as an important part of the course. Apart from
maintaining equity between students, deadlines enable them to demonstrate the ability to schedule
their work properly. Students are expected to meet all deadlines. The penalty for failing to do so is an
immediate reduction of 20% of the mark obtained; and no marks for any work submitted more than 24
hours late. A case for special circumstances, may be made to the Course Adviser, directly or via the
College Tutor.
Students are required to submit work in word-processed format and students should find opportunity to
develop their word-processing skills. Students should submit an additional electronic copy of their work
to the Course Adviser by placing a document in her Drop-to Folder on Freddi, the departmental server or
emailing it as a WORD attachment. All electronic copies should be labelled clearly with name,
supervisor’s initials and the date: e.g. ‘KellyAineEssay (RA).doc’. This procedure has two advantages.
Firstly, it is additional evidence of submission; secondly it enables the Course Adviser to review the work,
to assess it using the College plagiarism software (as on the Department website) and to provide
additional feedback on writing skills.
Examinations
There will be three three-hour papers and students will be required to attempt five questions (nominally
35 min each) from each paper. A small element of choice may be available. Marks are weighted
according to the number of credits in each course; hence the papers are not of equal weight. Not all
courses at assessed at the annual examinations; some are assessed in-course only. A summary of the
courses to be examined in each paper and the total number of marks in each paper will be made
available in Hilary Term. In addition to the descriptors listed on the Department website, students are
expected to demonstrate an understanding of physiological principles and mechanisms. 10% of the
final mark from JS year (Physiology Courses only) will be carried forward toward to the final
examination mark in Senior Sophister year.
Student Feedback
Students have a right to access their written work, including examination answers, as part of the learning
process. Supervisors of in-course assessments will provide marks as well as written comments on work
designed to indicate deficiencies in knowledge or its application as well as presentation. The aim is to
assist students to improve in all aspects of their work. Supervisors will also be available to discuss work
with individual students. Access to examination answers is via the Course Adviser who will usually refer
specific queries to the relevant examiner. The Course Adviser will issue breakdowns of marks to all
students after the examination process is complete at the end of the year (late June). The College
mechanism for getting breakdowns is to apply directly to the Course Adviser or Head of Discipline
(Calendar).
In addition, students will be asked once a term to complete feedback forms on each course. This exercise
is available to measure the student experience and make steady improvements to the quality of teaching
in the Department. Students may also make confidential comments to the Course Adviser.
Transferable skills
A key aim of the Physiology Moderatorship is that each student, as a result of successfully completing the
Sophister years in Physiology, will acquire and/or develop a range of transferable skills. See website for
document.
Choosing a Final-Year Project
The practical project is a major part of the final year. You should give serious thought to the area in which
you wish to work. Students should approach members of staff to discuss possible topics. Students are
also encouraged to develop their own projects - every effort will be made to facilitate them. Students will
be provided with a list of project supervisors and topics in early Michaelmas Term of your final year and
are required to submit a list of preferences. Final allocation of projects will be made early in the term.
While every effort will be made to allocate each student his/her preferred project, due to the number of
student projects to be accommodated, we reserve the right to assign students to specific projects.
Vacation Work
If you wish to work in the Department (or in a clinical department) during the Long Summer Vacation,
contact the relevant member of staff. Sometimes funding is available for such work, but it usually has to
be applied for in February/mid-March.
Funding sources include the Physiological Society, Wellcome Trust and Health Research Board, but you
will need to be put forward for this funding by a member of staff. There is also the SPUR-ON summer
scheme in Neuroscience, jointly run by the RCSI and TCIN.
Class Descriptors
The Science Faculty Descriptors are given as a guide to the qualities that assessors are seeking in relation
to the grades usually awarded. A grade is the anticipated degree class based on consistent performance
at the level indicated by an individual answer. In addition to the criteria, listed the Department's
examiners will also give credit for evidence of critical discussion of facts or evidence. See website for full
document.
Preparing Material for Oral Presentations
Students are required to make oral presentations from time to time — another important skill. The usual
means of presenting visual information is by PowerPoint presentation. There are standardized college
templates for powerpoint which you can request from the Department Administration Office.
PowerPoint Version 1
PowerPoint Version 2
•
Legibility. Anything less than 18 pt body text will be difficult to read. Headings should be about 24
pt. Using a ‘sans-serif’ font (e.g. Helvetica, Arial) will often improve legibility. Times is not suitable for
projection. Bolding the text is helpful too.
•
Density. Five lines is the useful maximum; and bullet points are better than continuous prose. If you
are tempted to put more on, think again. Are you trying to write your speaking notes onto the screen?
It is not good technique to simply read out what is on the screen.
Instructions for Writing Reports: See website for document.
Plagiarism – Department Policy
Your attention is drawn to the College’s regulations on plagiarism (below), the improper use of others’
work. Plagiarism is a very serious offence and is against the spirit of proper academic and scientific
enquiry and will lead to the loss of credit for the work in question. In extreme cases, plagiarism may lead
to exclusion from College. The risk of inadvertent plagiarism is greater in Sophister and postgraduate
years because of the increasing use of primary sources (research papers). It is therefore essential to
develop good practice immediately. College has purchased software (www.turnitin.com), the primary
purposes of which are to ensure that students are referencing sources correctly and to detect cases of
plagiarism. This software compares a student’s submitted material with any material published on the
worldwide web and any material previously submitted to the website. This means that all assignments
submitted by the class can be compared with each other and with assignments submitted by previous
years’ classes, in addition to most published sources (journal articles, etc.). To this end, all written
assignments must be submitted in electronic form to the Course Adviser as well as in hard copy (and
electronic form if requested) to the staff member concerned. We must emphasise that the academic staff
of the Department do not believe that our students routinely engage deliberately in plagiarism.
However, it is very easy to unintentionally break the College’s rules on plagiarism by failing to reference
sources correctly. College does not make any distinction between cases of intentional and unintentional
plagiarism; both are punishable by the Junior Dean. We view the use of this software as an opportunity
to ensure that students are trained correctly in good practice in the use of primary sources.
Summary of plagiarism policy:
Students will receive instruction on good practice in the use of sources.
All assignments will be processed by the Course Adviser using the turnitin software.
Where a case of plagiarism is suspected, the student will meet with the Course Adviser and the staff
member who set the work and their concerns will be explained to him/her.
If it appears likely that plagiarism has occurred, advice will be taken from the Head of Department and
matters can proceed according to College policy (see below).
Wholesale copying of another student’s work or of large chunks of web-based or other material will not
be tolerated and the students concerned WILL be reported to the Junior Dean. In the interests of
training students in best practice, errors in citation of sources may not result in such measures being
implemented if they occur on one single occasion. Subsequent infringements of the College plagiarism
policy will not be tolerated.
On foot of a joint initiative between the Undergraduate and Graduate Studies Committees, a workinggroup reviewed the existing Calendar entry and current practices across College. It was deemed that the
particular register of the Calendar meant that the document was not as accessible for students as it
could be and, therefore, did not necessarily contribute to their understanding of what constitutes
plagiarism. Thus, the 2015-16 Calendar entry has been formulated in a more accessible way. It also
contains revisions relating to how cases or levels of plagiarism are classified and dealt with under
summary procedures.
In order to support students in understanding what plagiarism is and how they can avoid it, we have
created an online central repository to consolidate all information and resources on plagiarism. Up to
now, information has been spread across many sites, which can lead to confusion. Through the provision
of a central repository, it is hoped to communicate this information to students in a clearer and more
coherent manner.
The central repository is being hosted by the Library and is located at http://tcdie.libguides.com/plagiarism .
It includes the following:
(i) The 2015-16 Calendar entry on plagiarism for undergraduate and postgraduate students;
(ii) The matrix explaining the different levels of plagiarism outlined in the Calendar entry and the
sanctions applied;
(iii) Information on what plagiarism is and how to avoid it;
(iv) ‘Ready, Steady, Write’, an online tutorial on plagiarism, which must be completed by all
students;
(v) The text of a declaration which must be inserted into all cover sheets accompanying all
assessed course work;
(vi) Details of software packages that can detect plagiarism, e.g. Turnitin.
It is important to emphasise that all students, i.e., undergraduate and postgraduate new entrants and
existing students, will be required to complete the online tutorial ‘Ready, Steady, Write’. Linked to this
requirement, students in all departments will be asked to complete cover sheets when submitting
assessed work, which will contain the following declaration:
I have read and I understand the plagiarism provisions in the General Regulations of the University
Calendar for the current year, found at: http://www.tcd.ie/calendar
I have also completed the Online Tutorial on avoiding plagiarism ‘Ready, Steady, Write’, located at
http://tcd-ie.libguides.com/plagiarism/ready-steady-write
Example Junior Sophister Exam Breakdown
Junior Sophister Exam papers
Paper 1
Total
paper
marks
69.0
% of year
Recommended
time/Q
11.25
16.3
Sensory
11.25
16.3
30 min
Brain Q 1
11.25
16.3
30 min
Brain Q 2
11.25
16.3
30 min
24
34.8
60 min
FHM Q 1
17.5
20.7
FHM Q 2
17.5
20.7
36 min
16
19.0
36 min
Pharm Phys Q 1
16.7
19.8
36 min
Pharm Phys Q 2
16.7
19.8
36 min
GKH Q 1
16.7
16.7
GKH Q 2
16.7
16.7
30 min
CVS Q 1
25
25.0
45 min
CVS Q 2
25
25.0
45 min
16.7
16.7
30 min
Endocrine Regulation
Paper 3
% of
Muscle and Nerve
Respiration
Paper 2
Marks
Cell Physiology
84.4
100.1
11.50
14.07
16.68
30 min
36 min
30 min
Please note that this may vary from year to year. The final format for your exam will be established by
April 2013. You will be given further details at that time.
Please look at the website for examples of paper examination papers.