Name: _________________________________ ANATOMY & PHYSIOLOGY II System Assignment Blood and Immunity The purpose of this assignment is to ensure that you are working diligently to keep up with the material and to give you practice both researching answers and answering questions specifically and succinctly. To receive credit for this assignment, your answers must be in your own words, and: ❏ well-written, with terms correctly spelled. ❏ NOT copied from any course handouts; ❏ NOT be copied from your or any other textbook (with the exception of definitions); ❏ NOT be identical to another student’s answers; and ❏ NOT be dictated by academic support services in the ARC. The due date for this assignment will be announced in class. Due date: ________________ # Points: 40 S10 1. Definitions. Provide a simple, concise definition for the following terms (1 pt each): histamine allergy complement antibody opsonization antigen anemia 1 2. Fill in the blanks below to complete the negative feedback control of hematopoiesis (4 pts). 2 3. Four leukocytes are diagrammed below. First, follow the directions for coloring each leukocyte as it appears when stained with Wright’s stain. Then, identify each leukocyte type by writing the correct name in the blank below each illustration (1 pt each). A. Color the granules pale violet, the cytosol pink, and the nucleus dark purple. B. Color the nucleus deep blue and the cytosol pale blue. C. Color the granules bright red, the cytosol pale pink, and the nucleus red/purple. D. For this smallest white blood cell, color the nucleus deep purple-blue and the sparse cytosol pale blue-green. 3 4. Using the following terms, fill in the circled, numbered, blank spaces to complete the concept map (4 pts). Factor VII and Ca++ Platelets Thrombin Active factor IX Intrinsic pathway Inactive factor XI Fibrinogen Tissue damage 4 5. Complete the following table concerning ABO blood groups (4 pts). Blood type Antigens present Type A A Can donate blood to type Can receive blood from type anti-A Type B AB Type AB Type O Antibodies in plasma None 6. What happens to red blood cells if incompatible blood types are mixed? (1 pt) 7. Can a type AB man produce a child with type O blood? Explain (1 pt). 8. How might a person with Rh- blood develop antibodies to the Rh factor? (1 pt) 5 9. Using the following terms, fill in the circled, numbered, blank spaces to complete the concept map (5 pts). Active immunization Transfer of antibodies Acquired Nonspecific immunity Inflammation Passive immunization Active Phagocytic cells Specific immunity Innate 6 10. Briefly describe the function(s) of the following immune cells (1 pt each): cytotoxic T (Tc) cell helper T (Th) cell antigen-presenting cell (APC) plasma cell 11. Describe how antibodies are useful to the immune system (1 pt). 12. A scientist working in a research lab has treated a dish of mutant cells with a fluorescent molecule that specifically binds to MHC proteins. Under the microscope, the fluorescent molecule appears in the cell’s Golgi apparatus. a. Is this an expected result? YES NO (1 pt) b. Should the scientist expect these cells’ MHC proteins to function normally? Why or why not? (1 pt) 7 The figure below illustrates an important principle in human immunity, especially for those who work in clinical settings. 13. In your own words, describe what this figure is demonstrating (1 pt). 14. How would you use this information when educating a patient (or a patient’s family member) about his/her condition? (1 pt) 8
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