American Journal of Epidemiology © The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: [email protected]. Vol. 181, No. 10 DOI: 10.1093/aje/kwu355 Advance Access publication: April 3, 2015 Original Contribution Sickness Absence and Psychosocial Job Quality: An Analysis From a Longitudinal Survey of Working Australians, 2005–2012 Allison Milner*, Peter Butterworth, Rebecca Bentley, Anne M. Kavanagh, and Anthony D. LaMontagne * Correspondence to Dr. Allison Milner, McCaughey VicHealth Centre for Community Wellbeing, Melbourne School of Population and Global Health, Level 5, 207 Bouverie Street, University of Melbourne, Melbourne, VIC 3010, Australia (e-mail: [email protected]). Initially submitted June 19, 2014; accepted for publication December 1, 2014. Sickness absence is associated with adverse health, organizational, and societal outcomes. Using data from a longitudinal cohort study of working Australians (the Household, Income and Labour Dynamics in Australia (HILDA) Survey), we examined the relationship between changes in individuals’ overall psychosocial job quality and variation in sickness absence. The outcome variables were paid sickness absence (yes/no) and number of days of paid sickness absence in the past year (2005–2012). The main exposure variable was psychosocial job quality, measured using a psychosocial job quality index (levels of job control, demands and complexity, insecurity, and perceptions of unfair pay). Analysis was conducted using longitudinal fixed-effects logistic regression models and negative binomial regression models. There was a dose-response relationship between the number of psychosocial job stressors reported by an individual and the odds of paid sickness absence (1 adversity: odds ratio (OR) = 1.26, 95% confidence interval (CI): 1.09, 1.45 (P = 0.002); 2 adversities: OR = 1.28, 95% CI: 1.09, 1.51 (P = 0.002); ≥3 adversities: OR = 1.58, 95% CI: 1.29, 1.94 (P < 0.001)). The negative binomial regression models also indicated that respondents reported a greater number of days of sickness absence in response to worsening psychosocial job quality. These results suggest that workplace interventions aiming to improve the quality of work could help reduce sickness absence. cohort studies; employment; job quality; job stressors; psychosocial factors; sickness absence Abbreviations: CI, confidence interval; HILDA, Household, Income and Labour Dynamics in Australia; IRR, incidence rate ratio; OR, odds ratio. rather than examining measures of the overall psychosocial quality of a job. Aside from this, past studies in this area have been based on specific occupational or organizational contexts (2, 6, 8), and results may not have been generalizable across skill levels or occupational groups in different working populations. Further, we are not aware of other studies of the job stressor–sickness absence association based on the experience of the same individual over time using fixed-effects regression models—a more causally robust approach than comparing people with one another in between-person analysis, which is more prone to confounding due to stable within-person characteristics (9). We sought to examine the relationship between changes in an individual’s overall psychosocial job quality and variation in sickness absence using data from a longitudinal cohort Absence from work due to sickness results in millions of lost working days and high health- and productivity-related expenditures each year (1), as well as being associated with greater risk of ill health and mortality (2, 3). The main predictors of sickness absence reflect both individual (e.g., relationship status, health conditions) and workplace (e.g., low job control, lack of perceived fairness at work) factors (4, 5). From a population health perspective, identifying the modifiable factors that contribute to sickness absence and intervening in these factors is likely to have benefits for both employers and society. Despite a number of previous studies on sickness absence, there are still gaps in current knowledge, particularly with regard to the work environment. This is because previous studies have usually examined job stressors individually (6, 7) 781 Am J Epidemiol. 2015;181(10):781–788 782 Milner et al. study of working Australians. We used the psychosocial job quality measure developed by Butterworth et al. (10–12) and extended 1- or 2-stressor models, such as job strain (the combination of high demands and low control), by including other prominent psychosocial working conditions in contemporary employment, such as job insecurity and perceptions of unfair pay relative to effort/contribution. The measure was developed and validated for use in the Australian context and has been studied in relation to mental health (10) and physical functioning (11). The current study represents an important and novel extension of this work by examining whether this scale of psychosocial job quality is also a predictor of sickness absence. The specific questions we addressed in this study were: 1) Does the psychosocial quality of a job influence whether a person takes paid sickness leave? and 2) Does the psychosocial quality of a job influence the amount of paid sickness leave a person takes? Further, because a number of studies have found different relationships between psychosocial job stressors and sickness absence for males and females (6, 13), we also investigated whether the relationship between psychosocial job quality and sickness absence was modified by sex. METHODS Data source The Household, Income and Labour Dynamics in Australia (HILDA) Survey is a longitudinal, nationally representative study of Australian households established in 2001. It collects detailed information annually from over 13,000 individuals within over 7,000 households (14). The survey covers a range of dimensions, including social, demographic, health, and economic conditions, using a combination of face-toface interviews with trained interviewers and a self-completion questionnaire. Additional information on the HILDA cohort can be seen in the report by Wilkins (14) and in the Web Appendix (available at http://aje.oxfordjournals.org/). Outcome variable The primary outcome in this study was a self-reported measure of whether the respondent had had any paid sickness absences in the 12 months prior to the interview and previous to the last HILDA survey, as identified through the question, “During the last 12 months, have you taken any paid sick leave?” The secondary outcome was a self-reported measure of the number of days of paid sick leave a person had taken in the 12 months prior to the interview and previous to the last HILDA survey. This was ascertained through the question, “How many days did you spend on paid sick leave (in the past 12 months)?” This variable was used to calculate an incidence rate ratio (number of sick days in the past year/total number of days in the past year). Information on paid sickness absence is available in the HILDA data set from 2005 onwards. Exposure variable Using the measures of psychosocial job characteristics available in the HILDA Survey ( job control, demands and complexity, job insecurity, and perceptions of unfair pay), we constructed a multidimensional indicator of overall job quality. Full details on the construction and validation of the job quality measure are presented elsewhere (10–12) and can be seen in the Web Appendix. Other variables Variables controlled for in the analytical models were selected on the basis of past research (4, 5). Only variables identified as possible causes of both psychosocial job quality and sickness absence were included in analysis (confounders); possible mediators lying on the causal pathway were excluded (see Web Figure 1). The variables included in the analysis were age (measured continuously in years as a timevarying factor) and household structure (couple or lone adult residing with dependents, couple without dependents, lone individual without dependents, or group or multiple-person household). The latter variable provided an indication of both relationship status and the presence of children within a household. We also included employment arrangement (permanent employment vs. fixed-term contract), occupational skill level (low, low-medium, medium-high, or high, according to Australian and New Zealand Standard Classification of Occupations groupings (15)), educational attainment (no completion of high school, completion of high school, vocational certificate/diploma, or bachelor’s degree or above), equivalized annual household income (in tertiles), and presence of a long-term health condition, disability, or impairment (yes/no). Analytical sample In HILDA, about 70% of permanent employees and 63.1% of fixed-term contract employees reported having a paid sickness absence in the past year (fixed-term contract workers tend to have working conditions similar to those of permanent workers, with the exception of a specified end date) (16), as compared with 7.2% of casual or temporary workers and 6.8% of self-employed persons. This reflects the fact that most casual employees and self-employed persons in Australia are not entitled to the same paid employment benefits (such as paid sick leave) as permanent employees (17). Because the main outcome in this study was paid sickness absence, casual employees and self-employed persons were excluded from the analysis. A flow chart outlining the steps used to select the final sample is presented in Figure 1. Information on missing data can be seen in the Web Appendix. Analysis Because items assessing paid sickness absence were first introduced to the HILDA Survey in 2005, the analysis included 8 waves of data collected annually between 2005 and 2012. Longitudinal fixed-effects logistic regression models were used to estimate the association between psychosocial job quality and the likelihood that a respondent had had at least 1 paid sickness absence (yes or no) in the previous 12 months. Coefficients were transformed into odds ratios to aid interpretability. Our analytical focus on within-person Am J Epidemiol. 2015;181(10):781–788 Sickness Absence and Psychosocial Job Quality 783 Entire HILDA Cohort 26,965 persons 165,299 observations Employed, With Information on Job Quality Measure and Data on Paid Sickness Absence 15,558 persons 55,106 observations Had Data on Paid Sickness Absence (Yes/No) in Past Year 15,588 persons 55,106 observations Logistic Regression Analysis 2,991 persons 13,895 observations Had Data on No. of Days of Paid Sickness Absence in Past Year 13,944 persons 47,617 observations Negative Binomial Regression Analysis 10,091 persons 31,224 observations Figure 1. Selection of the study sample into different logistic regression models, Household, Income and Labour Dynamics in Australia (HILDA) Survey, 2005–2012. Longitudinal fixed-effects logistic regression models were used to estimate the association between psychosocial job quality and the likelihood that a respondent had had at least 1 day of paid sickness absence (yes or no) in the previous 12 months. Negative binomial regression models were used to examine the number of days of paid sickness absence in the past year. Only persons with complete data on all relevant covariates were included in the analyses. associations over time in the survey meant that each individual included in the HILDA data set acted as his or her own control (e.g., 1, 2, and 3 or more adversities were compared with having a psychosocially optimal job) (see Web Table 1). This provided estimates that were not confounded by timeinvariant personal, demographic, and environmental factors, which were statistically removed from the model (9). Hence, to be included in the logistic regression analysis, respondents had to have at least 1 wave each of “yes” and “no” responses to the question, “During the last 12 months, have you taken any paid sick leave?” We controlled for time-variant factors by including relevant covariates in the fixed-effects models. We tested the possibility that the relationship between psychosocial job stressors and sickness absence differed for males and females by assessing the significance of the interaction terms and the results of a likelihood ratio test. We also evaluated possible effect modification by age (assessed in 10-year age groups) as well as by whether a person worked full-time or part-time, in order to assess the robustness of the relationship between psychosocial job quality and sickness absence. We did this by including an interaction term in the logistic regression models and comparing this against a model with main associations only. As above, we used the likelihood ratio test and inspected individual interaction terms in assessing evidence of an interaction. We then modeled the number of days of sickness absence during the year. Negative binominal regression was used to Am J Epidemiol. 2015;181(10):781–788 model the relationship between sickness absence and job quality, since there was evidence of overdispersion in the outcome variable. Because of problems involved in fitting fixed effects in negative binominal panel models in commercial statistical software packages such as STATA (StataCorp LP, College Station, Texas) (18), we generated the difference scores manually (i.e., deviation from each person’s mean score for all time-varying covariates (19)) and implemented the model as a random-effects model. This produces estimates consistent with those of a fixed-effects model but avoids the incidental parameters problem, as it does not require the estimation of individual-specific parameters (19). Coefficients were transformed into incidence rate ratios to ease interpretation. As a sensitivity analysis, we characterized the difference of the between-person (by including the mean value of each variable in the regression analysis) and randomeffects models from the fixed-effects within-persons approach described above (Web Tables 2 and 3). For both the logistic and negative binominal models, we first derived results from a simple model representing the association between the key exposure variable and the outcome, before adjusting for other relevant confounders. Analyses were performed using STATA, version 12.1 (18). RESULTS Table 1 provides information on the demographic characteristics of the analytical sample at entry into the HILDA Survey (i.e., baseline). As explained above, to be included in the logistic regression analysis, respondents had to have experienced a change in sickness absence—that is, reported both “yes” and “no” to the question, “During the last 12 months, have you taken any paid sick leave?” There were slightly more males in this sample than females, and most workers were of a higher skill level. At baseline, 50% of this group reported having 1 psychosocial job stressor, approximately 35% were employed in high-skill jobs, and the majority were living with no dependents. Most people in this group were employed permanently at baseline. Table 1 also shows the characteristics of persons included in the negative binomial analysis examining the number of days of paid sickness absence in the past year. These models were able to include persons with a sickness absence count of zero, which explains why there were more individuals included in them than in the logistic regression models. The baseline characteristics of this sample were similar to those of persons in the logistic regression analysis. The sample was much larger because the analysis could include persons who might take sickness absences every year but vary in terms of the number of days taken. Table 2 shows results from the fixed-effects logistic regression model assessing the role of psychosocial job quality in sickness absence, both before and after adjustment for other covariates. In the multivariate model, there was evidence of a dose-response relationship between the number of psychosocial job stressors a person reported and having a paid sickness absence. Compared with reporting no psychosocial job stressors, reporting 1 adversity was associated with a 26% rise in the odds of having a sickness absence (odds ratio (OR) = 1.26, 95% confidence interval (CI): 1.09, 1.45; P = 0.002). 784 Milner et al. Table 1. Baseline Characteristics (%) of Respondents in the HILDA Survey, 2005–2012a Type of Analysis Characteristic Logistic Regression (n = 2,991) Negative Binomial Regression (n = 10,091) Age group, years 15–24 22.47 24.36 25–34 22.73 23.43 35–44 24.37 23.11 45–54 22.10 19.60 55–64 7.79 8.41 ≥65 0.53 1.09 Male 53.63 49.97 Female 46.37 50.03 Lowest 14.68 13.62 Medium-low 24.31 26.31 Medium-high 25.94 24.78 Highest 35.07 35.29 Optimal 13.77 14.48 1 adversity 50.15 50.48 2 adversities 26.15 25.49 9.93 9.55 Sex Occupational skill level Psychosocial job quality ≥3 adversities Household structure Couple with no dependent(s) 46.67 42.61 Couple/lone adult with dependent(s) 33.80 36.38 Lone individual 16.78 15.96 2.74 5.04 Group/multiperson household Employment arrangement Permanent 86.73 85.70 Fixed-term 13.27 14.30 Abbreviation: HILDA, Household, Income and Labour Dynamics in Australia. a The logistic regression analysis included only those persons who reported a change in sickness absence in the past year (i.e., reported both yes and no), as identified through the question, “During the last 12 months, have you taken any paid sick leave?” The negative binomial regression analysis included persons who reported information on days of paid sickness absence in the past year, as identified through the question, “How many days did you spend on paid sick leave (in the past 12 months)?”. Reporting 2 adversities was associated with a 28% rise in the odds of a sickness absence (OR = 1.28, 95% CI: 1.09, 1.51; P = 0.002), while having 3 or more adversities was associated with a 58% rise (OR = 1.58, 95% CI: 1.29, 1.94; P < 0.001). When the job quality index was included as a continuous measure, the odds ratio for the continuous job quality measure was 1.12 (95% CI: 1.06, 1.19; P < 0.001). Results for other covariates indicated that respondents had lower odds of a sickness absence during times when they were working in fixed-term employment than when they were permanently employed, and that older age and long-term health conditions were related to greater odds of taking paid sick leave. There was an observable gradient in occupational skill level, showing that respondents were more likely to take paid sick leave when they were working in higher-skill jobs than when they were in lower-skill jobs. We then assessed the possibility that sex modified the association between psychosocial job quality and sickness absence. Results of the likelihood ratio test (χ2 (3 df ) = 6.57, P = 0.090) and inspection of interaction terms provided no support for significant sex differences. We also found no evidence of effect modification by age (χ2 (15 df ) = 13.81, P = 0.540) or by whether a person worked full-time or parttime (χ2 (3 df ) = 3.01, P = 0.390) in the relationship between sickness absence and job quality. Results from the negative binominal fixed-effects regression model (Table 3) indicated a dose-response relationship between the number of job-related adversities experienced by an individual and paid sickness absence. After adjustment for other covariates, there was a marginally nonsignificant 5% increase in the number of days of paid sick leave in relation to 1 adversity (incidence rate ratio (IRR) = 1.05, 95% CI: 1.00, 1.10; P = 0.058), a 7% increase in days of sick leave in relation to 2 adversities (IRR = 1.07, 95% CI: 1.02, 1.13; P = 0.010), and an 11% increase in days of sick leave when a person had 3 or more adversities (IRR = 1.11, 95% CI: 1.04, 1.19; P = 0.001). When the job quality index was included as a continuous measure, the incidence rate ratio was 1.03 (95% CI: 1.01, 1.05; P = 0.001). Results for other variables were similar to those from the logistic regression models. Findings from sensitivity analyses including between- and random-effects estimates are shown in Web Tables 2 and 3. Results were in the same direction as those from the fixedeffects analysis but were much greater in magnitude. Part of the difference may be explained by residual confounding from time-invariant factors (e.g., stable individual characteristics). The random-effects analyses also included betweenperson contributions to the coefficients, which potentially accounts for some of the increase in magnitude. DISCUSSION The results derived from these fixed-effects analyses provide stronger evidence of a causal relationship between psychosocial job quality and sickness absence than previous research. Compared with times when respondents were employed in jobs with optimal working conditions, experiencing a greater number of adversities at work was associated with increased odds of sickness absence as well as a greater number of days of sickness absence in the past year. This indicates that as the quality of a person’s work decreases, his or her likelihood of being absent from the workplace increases. Although there have been other studies on the relationship between job stressors and sickness absence (2, 5, 6, 8, 20), ours was the first (to our knowledge) to use a measure that operationalizes a continuum of psychosocial job quality across a working population and to evaluate the influence of combined Am J Epidemiol. 2015;181(10):781–788 Sickness Absence and Psychosocial Job Quality 785 Table 2. Odds of Paid Sickness Absence in the Past Year According to Psychosocial Job Quality and Sociodemographic Factors (Fixed-Effects Logistic Regression Model), HILDA Survey, 2005–2012 Bivariate Analysis OR 95% CI Multivariate Analysis P Value OR 95% CI P Value Psychosocial job quality Optimal 1 1 adversity 1.25 1.09, 1.44 Referent 0.002 1.26 1 1.09, 1.45 Referent 2 adversities 1.29 1.10, 1.51 0.002 1.28 1.09, 1.51 0.002 ≥3 adversities 1.58 1.29, 1.93 <0.001 1.58 1.29, 1.94 <0.001 0.002 Employment arrangement Permanent 1 Fixed-term 0.83 Referent 0.72, 0.95 1 0.009 0.83 Referent 0.72, 0.96 0.011 Tertile of household income Lowest 1 Medium 1.75 1.51, 2.03 <0.001 1.74 1.50, 2.02 <0.001 High 2.23 1.88, 2.65 <0.001 2.06 1.73, 2.46 <0.001 1.09 1.07, 1.11 <0.001 1.08 1.06, 1.10 <0.001 Age (per year) Referent 1 Referent Household structure Couple with no dependent(s) 1 Couple/lone adult with dependent(s) 0.66 0.56, 0.76 Referent <0.001 1 0.76 0.65, 0.88 Referent <0.001 Lone individual 0.93 0.77, 1.13 0.488 1.06 0.87, 1.30 0.550 Group/multiperson household 0.77 0.57, 1.03 0.076 0.80 0.60, 1.08 0.152 Long-term health condition No 1 Yes 1.24 Referent 1.07, 1.44 1 0.004 1.24 Referent 1.07, 1.44 0.004 Occupational skill level Lowest 1 Medium-low 1.24 0.97, 1.57 Referent 0.081 1.22 1 0.96, 1.55 Referent 0.106 Medium-high 1.36 1.09, 1.69 0.007 1.36 1.09, 1.71 0.007 Highest 1.71 1.34, 2.18 <0.001 1.57 1.22, 2.00 <0.001 Abbreviations: CI, confidence interval; HILDA, Household, Income and Labour Dynamics in Australia; OR, odds ratio. psychosocial working conditions rather than focusing on 1 or 2 conditions. Previous research using this measure has shown a relationship between worsening job quality and mental (10) and physical (11) health. Consistent with this past work, the present study also found a gradient between the number of adversities experienced at work and the likelihood of taking sick leave. Our adoption of a fixed-effects approach enabled us to focus on within-person change over time (rather than between-person analysis as in previous studies), comparing sickness absence under optimal job conditions with sickness absence under varying degrees of poorer psychosocial job quality. There may be a number of different interpretations for these results, depending on whether sickness absence is seen as a health outcome, a health behavior, or a combination of both. If sickness absence is viewed as a proxy for physical and mental ill health (e.g., a health outcome), a possible interpretation of our result is that a low-quality work environment is related to a decline in health. A relationship between measures of sickness absence and ill health and mortality has Am J Epidemiol. 2015;181(10):781–788 been demonstrated in numerous studies (2, 5, 21, 22). The consistency of these relationships is such that some researchers have suggested that sickness absence can be thought of as an overall global measure of health status (2). Other researchers have preferred to view sickness absence as a health behavior and have conceptualized it as a form of coping (22). In this case, workers may use sickness absence to avoid, reduce, or control their exposure to work-related stress and gain the opportunity to recover from adverse working conditions (22– 24). Thus, this may be a mediator on the pathway between psychosocial working conditions and health. The fact that our data continued to show the same pattern of association between psychosocial job quality and sickness absence after we controlled for long-term health conditions provides support for the second explanatory framework, acknowledging that these views are not mutually exclusive and that sickness absence may represent both a health behavior and a health outcome. Past results (13) have suggested that females have a higher number of sick days than males. However, we found no 786 Milner et al. Table 3. Incidence Rate Ratios for Number of Days of Paid Sickness Absence in the Past Year According to Psychosocial Job Quality and Sociodemographic Factors (Negative Binomial Regression Model), HILDA Survey, 2005–2012 Bivariate Analysis IRR 95% CI Multivariate Analysis P Value IRR 95% CI P Value Psychosocial job quality Optimal 1 Referent 1 Referent 1 adversity 1.05 1.00, 1.10 0.052 1.05 1.00, 1.10 0.058 2 adversities 1.07 1.02, 1.13 0.011 1.07 1.02, 1.13 0.010 ≥3 adversities 1.12 1.05, 1.19 0.001 1.11 1.04, 1.19 0.001 Employment arrangement Permanent 1 Fixed-term 0.87 Referent 0.84, 0.90 1 <0.001 Referent 0.85 0.81, 0.89 <0.001 Tertile of household income Lowest 1 Medium 1.21 1.16, 1.26 <0.001 1.21 1.15, 1.27 <0.001 High 1.32 1.25, 1.38 <0.001 1.30 1.23, 1.38 <0.001 1.03 1.03, 1.04 <0.001 1.03 1.02, 1.03 <0.001 Age (per year) Referent 1 Referent Household structure Couple with no dependent(s) 1 Referent 1 Referent Couple/lone adult with dependent(s) 0.92 0.88, 0.95 <0.001 0.95 0.90, 1.00 0.031 Lone individual 0.97 0.92, 1.02 0.238 0.99 0.93, 1.06 0.812 Group/multiperson household 0.97 0.90, 1.05 0.455 0.93 0.85, 1.02 0.144 Long-term health condition No 1 Yes 1.14 Referent 1 1.10, 1.18 Referent 1.18 1.13, 1.24 <0.001 Occupational skill level Lowest 1 Referent 1 Referent Medium-low 0.99 0.93, 1.06 0.803 1.00 0.92, 1.08 0.944 Medium-high 0.97 0.91, 1.03 0.336 1.01 0.94, 1.09 0.717 Highest 1.07 1.01, 1.15 0.031 1.11 1.02, 1.20 0.012 Abbreviations: CI, confidence interval; IRR, incidence rate ratio; HILDA, Household, Income and Labour Dynamics in Australia. evidence that sex modified the association between job quality and sickness absence. There has also been some suggestion that people who are socially isolated (6) or living alone (5) are at greater risk of sickness absence than those living with others. This aligns with our research, which found that living with children or dependents was associated with lower odds of sickness absence. In a French cohort study, employees in manual and clerical positions were found to have much higher levels of sickness absence than managers (7). In contrast, our study found that people were more likely to have more absences when they were employed in higher-skill positions than when they were employed in lower-skill positions. This finding probably reflects differences in the composition of the sample, which was comprised of permanent and fixed-term contract workers, who are more likely to be employed in jobs involving higher occupational skill levels. This result may also be explained by methodological differences, as our fixed-effects analysis focused on within-person change, while previous studies have involved within- and/or between-person analyses. One possible limitation of this study was its self-report measure of sickness absence. The use of this subjective outcome may have resulted in measurement error, as respondents may have failed to accurately report whether they had had any sickness absences in the past year and/or may have misreported how many days of sick leave they took. There is also a possibility of dependent misclassification, whereby people were more attentive to sickness absence during the years when they reported poor job quality than during the years in which their psychosocial job quality was better. We also acknowledge that our research was restricted to permanent and fixed-term employees in the Australian context (since these were the only people in Australia who were guaranteed to have access to paid sick leave—approximately 50%–60% of the working population). The observed relationships clearly are not generalizable to the remaining Am J Epidemiol. 2015;181(10):781–788 Sickness Absence and Psychosocial Job Quality 787 40%–50% of the Australian labor force, who are working in other employment arrangements (including temporary and labor-hire workers and the self-employed) (16). From a policy perspective, the lack of paid sick leave for such a large proportion of the labor force may indeed be a substantial driver of presenteeism. Last, the measure of job quality was also self-reported and based upon a specific set of constructs, as determined through factor analysis. There are many other important psychosocial aspects of the work environment (e.g., social support and bullying at work) that were not included in this measure or in this panel study, as well as aspects of the general working environment that could also have had an influence on our results, suggesting that this study provided a conservative estimate of the influence of workplace psychosocial stressors on paid sickness absence. In addition to the number of stressors a person is exposed to, the duration of exposure may be an important aspect of the relationship and warrants further study. Despite these limitations, there were also a number of strengths in this study. These included the ability to examine the relationships between psychosocial working conditions and sickness absence over time using a large representative national sample. We were able to use a previously validated measure of psychosocial job quality, shown to be associated with mental and physical health and more objective aspects of work in the Australian context. The fixed-effects analytical approach allowed us to examine causally robust withinperson associations while controlling for time-invariant confounders that may have otherwise biased the results, even though the estimates obtained are (strictly speaking) generalizable only to those respondents who reported changes in both exposure and outcome during their contributed waves (and not to the entire source population). Selection bias is likely to have been limited, as we only had a small proportion of missingness in the data set. Based on these findings, we conclude that psychosocial job quality is a significant predictor of sickness absence in the Australian context. These results suggest that improving the overall psychosocial quality of work may lead to a reduction in sickness absence. Such an approach aligns with the growing recognition that workplace-based interventions will have the largest population benefit when they systematically address risk and protective factors at the primary, secondary, and tertiary levels (25). ACKNOWLEDGMENTS Author affiliations: McCaughey VicHealth Centre for Community Wellbeing, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia (Allison Milner, Anthony D. LaMontagne); Centre for Research on Ageing, Health and Wellbeing, ANU College of Medicine, Biology and Environment, Australian National University, Canberra, Australian Capital Territory, Australia (Peter Butterworth); Gender and Women’s Health Unit, Centre for Health Equity, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia (Rebecca Bentley, Anne M. Kavanagh); and PopulaAm J Epidemiol. 2015;181(10):781–788 tion Health Strategic Research Centre, School of Health and Social Development, Deakin University, Melbourne, Victoria, Australia (Anthony D. LaMontagne). This work was supported by the Australian National Health and Medical Research Council (NHMRC) through both project (grant 375196) and postdoctoral research fellowship (to A.M.) (NHMRC Capacity Building Grant 546248) funding. This study also received center grant funding (grant 15732) from the Victorian Health Promotion Foundation (Melbourne, Victoria, Australia). The data used in this paper were extracted by means of the add-on package PanelWhiz for Stata. PanelWhiz (http://www. PanelWhiz.eu) was created by Dr. John P. Haisken-DeNew ( [email protected]). This study used unit record data from the Household, Income and Labour Dynamics in Australia (HILDA) Survey. 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