Table Liver function in mice after CRA treatment
AST (IU/L)
ALT (IU/L)
T-Bil. (mg/dL)
ALP (IU/L)
GGT (IU/L)
Total protein (g/dL)
Albumin (g/dL)
Globulin (g/dL)
BUN (mg/dL)
Glucose (mg/dL)
Bile acids (umol/L)
Vehicle injection
(n = 5)
114.6 ± 36.1
37.2 ± 5.5
0.1 ± 0.0
136.0 ±15.5
1.0 ± 0.0
4.2 ± 0.3
2.7 ± 0.2
1.5 ± 0.1
23.4 ± 0.9
289.8 ± 66.5
2.7 ± 0.4
CRA injection
(n = 5)
133.0 ± 80.6 (P = 0.654)
48.6 ± 15.4 (P = 0.158)
0.1 ± 0.0
199.6 ±31.6 (P = 0.004)
1.0 ± 0.0
4.5 ± 0.3 (P = 0.189)
2.9 ± 0.2 (P = 0.071)
1.5 ± 0.2 (P = 0.659)
24.2 ± 2.8 (P = 0.557)
280.6 ± 108.0 (P = 0.875)
2.6 ± 1.3 (P = 0.825)
Data represent mean ± s.d. (n = 5). In parenthese, P values, by Student's t-test, compared
with the no-treatment group. IU, international units; AST, aspartate aminotransferase;
ALT, alanine aminotransferase; T-Bil, total bilirubin; ALP, alkaline phosphatase; GGT,
g-glutamyl transpeptidase; BUN, blood urea nitrogen.