Kelso High School Biology Cell Division and Reproduction Name……………………..... Class……….. Keep this booklet safe – you will need it for revision. Cell Division and Reproduction Use this table as a checklist for your Use the smiley faces to show how well you are coping revision. = core = challenge Understood and learnt Level Need to do more work Need to get help - see my teacher. You need to be able to…… State that cell division increases the number of cells in a growing organism or replaces damaged cells in an organism State that mitosis is another name for cell division Identify the correct sequence of stages in mitosis Describe what happens during each of the stages of mitosis State that mitosis produces two genetically identical daughter cells Explain why it is important that the daughter cells contain the same number of chromosomes as the original cell Explain the role of gametes in sexual reproduction State the names and functions of the parts of the male and female reproductive systems Explain the differences between internal and external fertilisation Describe the events that occur during the fertilisation of an egg and implantation of the embryo in the uterus Describe the stages of development in human embryos and the structures relating to the site of development Describe the structure of the placenta and how materials are exchanged between mother and foetus Discuss some of the possible risks to the development of an embryo 2 Cell division The nucleus of a cell controls all the cell’s activities, including cell division. The nucleus contains ___chromosomes______ . ___Chromosomes__________ are made up of genes. Genes are made of ___DNA_________ . Genes control the size, shape and function (job) of the cell. The process of cell division is also called __mitosis_____ . Mitosis is the way the number of cells is increased in a plant or animal. This is how we grow and repair damaged tissues. Mitosis When a cell is about to divide, thread-like structures called ____chromosomes__________ appear in the nucleus. Each new cell (daughter cell) made by mitosis has a complete copy of the DNA in the original cell i.e. it is ___genetically_____ identical to the original cell. Since the new daughter cells have exactly the same number of chromosomes, the cells will function normally. The new daughter cells are _genetically___ identical to the original cell. The chromosomes are copied before the cell divides: 3 Label the diagram below to show the structure of a cell that is about to divide: nuclear membrane chromosome centriole Stages of Mitosis 1. The __chromosomes__ have duplicated. They start to become visible in the nucleus. 2. The nuclear membrane breaks down and the _centrioles_ go to the poles of the cell. The chromosomes are now visible. 3. The chromosomes move towards the _equator_ of the cell. The spindle fibres start to form. 4. The chromosomes have lined up along the equator and the _spindle_ fibres__ have attached to their centromeres. 5. The spindle fibres contract, separating the chromosomes, pulling them to opposite _poles_ of the cell. 6. The __cytoplasm__ starts to divide. 7. Two _genetically___ identical daughter cells are formed. 4 Reproduction All plants and animals reproduce (produce new offspring). If they did not reproduce, the species would soon become extinct. Most animals reproduce by sexual reproduction, involving two parents, each producing specialised cells called gametes. In animals the males produce gametes called sperm in the testes and the females produce eggs (ova) in ovaries. [Plants also produce gametes called ovules and pollen.] sperm egg(ovum) Male Reproductive System sperm duct urethra testis penis Structure Function testes Sperm are produced here urethra Tube running down the centre of the penis for transport of sperm sperm duct Transports sperm from the testes penis Passes sperm from male’s body into female’s body during intercourse 5 Female Reproductive System oviduct ovary uterus vagina Structure Function ovaries Eggs (ova) are stored and produced here oviduct (fallopian tube) Transports the egg (ovum) towards the uterus uterus Fertilised egg becomes implanted and embryo develops here vagina Penis enters this tube (which leads to the uterus) and deposits sperm here External Fertilisation Water is required to allow the sperm to swim towards the eggs and fertilise them. Fertilisation can occur outside the organisms body e.g. in fish, where the eggs and sperm are deposited in a hollow in the gravel on the bottom of the riverbed or ocean. This is known as external_ __fertilisation__. Fish must produce many more eggs and sperm than mammals to overcome the following problems: • Some eggs may not be _fertilised_ • Some eggs/ young may be eaten by predators • Some _eggs_/ young may become diseased and die. By producing high numbers of gametes, these fish ensure that at least some of the offspring will survive to adulthood and have offspring of their own. 6 Internal Fertilisation In mammals (e.g. humans), there is no water for the sperm to swim towards the egg, so the sperm is deposited __inside__ the female. This is known as internal fertilisation. Internal fertilisation starts with copulation, when millions of __sperm__ are released into the vagina, swim up through the uterus and into the ___oviduct_where fertilisation takes place, if an egg is present. _Fertilisation___ occurs when the nucleus of the sperm fuses with the nucleus of the egg (ovum). This results in the formation of a single fertilised egg cell called a zygote. The __zygote_ is the first cell of a new organism. Implantation This cell will begin to divide by __mitosis__ to create a ball of cells called the embryo. The embryo moves along the oviduct towards the __uterus__, where it becomes implanted. sperm egg (ovum) lining of uterus ovary 7 Development of Human Embryo The embryo (now called the foetus) stays inside the mother’s body during its development, the mother provides everything the foetus needs to grow and develop via the _placenta_ . placenta umbilical cord foetus amniotic fluid muscular wall of uterus amnion (amniotic sac) Structure Function amnion Also known as the amniotic sac. Contains amniotic fluid. amniotic fluid Protects the foetus from bumps and damage, as the mother moves around. umbilical cord Contains blood vessels which deliver food and oxygen to the foetus and carry carbon dioxide and urea back to the mother placenta Where the mother’s and foetus’ blood come close together (but do not mix) to allow materials to be exchanged foetus Develops into a baby uterus The foetus develops here during pregnancy. Has a muscular wall that contracts during labour 8 Stages of Development of a Foetus 9 Exchange of Materials Across the Placenta _Food__ and ___oxygen__ pass from the mother’s blood to the embryo. ___Carbon__ __dioxide___ and waste materials (e.g. urea) pass from the __foetus_ to the mother across the placenta. Risks to the Foetus during Development It is now known that as well as food and oxygen, many other substances can cross the placenta during pregnancy and cause harm to the foetus during development. Use the information from the class presentations to complete the table below, to show the risks that can occur during development of the foetus: Risk Drinking alcohol Smoking Problem caused during development • • • Effect on development of foetus Drinking excessive quantities of __alcohol__ during pregnancy can cause the blood vessels in the umbilical cord to collapse, preventing ___food__ and __oxygen__ reaching the foetus • • Lower the amount of oxygen available to the mother and baby. Increase the baby's __heart___ rate. • • • • Increased chance of _miscarriage__ If a mother drinks heavily during pregnancy, the baby could develop a group of problems known as _Foetal__ __Alcohol__ _Syndrome_ (FAS). Children with this syndrome have: ¾ restricted growth ¾ facial abnormalities ¾ learning and _behavioural__ disorders Increase the chances of miscarriage and stillbirth. Increase the risk that the baby is born prematurely and/or born with a _low__ birth weight. Increase the baby's risk of developing respiratory ( lung) problems 10 Use the table below to note any further relevant risks to the development of the foetus that were discussed during the class presentations: Other Risks Problem caused during development Effect on development of foetus As appropriate from class discussion Methods of Contraception Complete the table below to show some of the methods of contraception you have researched and there effectiveness: (data used for this table is taken from NHS website: http://www.nhs.uk/chq/Pages/825.aspx?CategoryID=117&SubCategoryID=114, Feb 2013) Method of Contraception Effectiveness Male condoms 98% if used correctly Female condoms 95% if used correctly Combined contraceptive pill 99% if taken correctly Contraceptive implants/ injections 99% Female sterilisation 99% [End of topic] 11
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