Lipid Chemistry Presented By Ayman Elsamanoudy Salwa Abo El-khair 7 A lipid containing alcoholic amine residue is all except: (A) Phosphatidic acid (B) Ganglioside (C) Glucocerebroside (D) Sphingomyelin Kerasin consists of (A) Nervonic acid (B) Lignoceric acid (C) Cerebronic acid (D)3 Arachidonic acid Molecular formula of cholesterol is (A) C27H45OH (B) C28H49OH (C) C29H47OH (D) C23H41OH Which of the following is omega-3 polyunsaturated fatty acid? (A) Linoleic acid (B) Linolenic acid (C) Palmitoleic acid (D) Arachidonic acid 4 Acylsphingosine is also known as (A) Sphingomyelin (B) Ceramide (C) Cerebroside (D) Sulphatide All the following have 18 carbon atoms except (A) Linoleic acid (B) Linolenic acid (C) Arachidonic acid 5 (D) Stearic acid Cholesterol is transported from liver to extrahepatic tissues by (A) Chylomicrons (B) VLDL (C) HDL (D) LDL The cyclic ring present in all the steroids: (A) Cyclopentano perhydrophenanthrene (B) Nitropentano (C) both (A) and (B) (D) None of these 6 Instead of ester link plasmalogens possess an ether link in position: (A) α (B) β (C) γ (D) None of these The concentration of sphingomyelins are increased in (A) Gaucher’s disease (B) Fabry’s disease (C) Fabrile disease 7 (D) Niemann-Pick disease Sphingomyelins contain a complex amino alcohol named as (A) Serine (B) Lysolecithin (C) Sphingosine (D) Glycol Δ9 indicates a double bond between carbon atoms of the fatty acids: (A) 8 and 9 8 (B) 9 and 10 (C) 9 and 11 (D) 9 and 12 The prostaglandins are synthesized from (A) Arachidonic acid (B) Oleic acid (C) Linoleic acid (D) Palmitic acid Depot fats of mammalian cells comprise mostly of (A) Cholesterol (B) Cholesterol esters (C) Triacyl glycerol 9 (D) Phospholipids A fatty acid which is not synthesized in the body and has to be supplied in the diet is: (A) Palmitic acid (B) Stearic acid (C) Linolenic acid (D) Palmitoleic acid The number of double bonds in arachidonic acid is (A) 2 (B) 3 (C) 4 (D) 6 10 Case History Case I Underweight female was born at 27 weeks of pregnancy ( pre-term baby). With rapid heart rate, increased respiratory rate . Chest X-ray revealed bilateral lung collapse. Care plan included maintenance IV fluids and treatment using surfactants as 100ml/kg. a. What is your possible diagnosis? b. What is the biochemical basis of this case ? c. Explain the structure of the deficient substance. GREAT THANKS Ayman Elsamanoudy Salwa Abo El-khair 11/17/2014 Ahmed A.Albadry 12
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