Redwood High School, Integrated Science Unit Outline
v.15
Integrated Science 2: Health and Disease
The Story: The goal of the Health and Disease Unit is to investigate cells and introductory genetics through the
study of human disease. In our previous study of the origins and evolution of life on Earth we considered
phenotypic variation. We will now study human disease, and the biology of the pathogens involved. Continuing
within this line of investigation, we will use disease as a means of studying the structure and function of the
cell, and cell reproduction. We will also study how the human immune system functions to combat these
pathogens. The unit will be separated into two parts.
Student Outcomes:
Part 1: Pathogens, Cells, and Immune Response
❒ define pathogen, and give examples
❒ compare and contrast the basic biology of: Bacteria, Protists, Fungi, Invertebrates, Viruses
❒ explain the role of animals in the transmission of disease
❒ explain the major points of the Cell Theory
❒ explain the differences, and similarities between prokaryotic and eukaryotic organisms, and between plant
and animal cells
❒ identify, and explain the function, of the major organelles
❒ discuss how vaccines and antibodies are used to combat disease
❒ describe the structure and function of the human immune system
Part 1 Possible Reading and Questions
Bacteria: Read 805-11 AND 818-21, Do 811 #1-6 AND 824 #1-2
Virus: Read 812-17 AND 822-24, Do 817 #1-5 AND 824 #3
Pathogen Kingdoms (Protists, Fungi, Animals): Read 831-32, 37-9 AND 861-63, 72-4 AND 887-893
Immune System: Read 1025-36, Do 1036 #1-5
Part 2: Genetics and Genetic Disorders
❒ describe mitosis – including what happens in each stage
❒ demonstrate the ability to predict genetic outcomes using Punnett squares
❒ using a diagram, compare and contrast mitosis and meiosis
❒ describe the cause, symptoms, and treatments of genetic disorders
Part 2 Possible Reading and Questions
Mitosis: 738-42, Do 743 #1-5 (Ch 26)
Meiosis: 767-70, Do 770 #1-5 (Ch 27)
Genetic Disorders: 779-791, Do 791 1-5 (Ch 28)
Genetics: 755-761 [and 762-3 (dihybrid)], Do 761 #1-5 (Ch 27)
Unit Skills:
• microscopy • mathematical prediction (Punnett squares) • experimental design • culturing of microorganisms
Focus Questions, Corresponding Concepts:
1. How does disease affect organisms at the cellular level? Cell structure and function, Prokaryotic vs.
eukaryotic organisms, Mitosis, (Optional: Reproduction and Development)
2. What are genetic disorders? Meiosis, Mendelian Genetics (monohybrid), Genetic Disorders: inherited and
developmental, Genetic screening
3. What are the major types and characteristics of disease-causing pathogens? The basic biology of Bacteria,
Protists, Fungi, Invertebrates, Viruses
4. How do humans combat infectious disease? Immune system, Treatments, Prevention
Over for Health and Disease Table of Contentsà
Integrated Science v.15
Name
Date
Period
Table of Contents – Health and Disease Unit
Page
Assignment
Score
Page
1.
26.
2.
27.
3.
28.
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29.
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30.
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31.
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32.
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33.
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34.
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35.
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36.
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37.
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38.
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39.
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40.
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41.
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42.
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43.
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44.
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45.
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46.
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47.
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48.
24.
49.
25.
50.
Over for Health and Disease outlineà
Assignment
Score