2017 Science Research Conference (SRC) Directory e g a g n E e t u b i r nt n r a Le e r lo p x E Co REGISTER NOW! www.FASEB.org/SRC Invitation to Attend Dear Prospective Attendee, On behalf of the FASEB Science Research Conferences program, we would like to invite you to participate in our 2017 conference series. FASEB SRCs are held annually at several locations worldwide, with an average of 100 to 150 attendees per conference. These intimate settings allow attendees to have in-depth discussions about the science presented, its future, and the contributions they hope to make in their respective fields. Each meeting spans five days, allowing time for established scientists to share their work and for trainees to participate in Meet-the-Expert Sessions. Participants also have the opportunity to present their research either as short-talks or during poster sessions. In addition, the SRCs provide a welcoming environment for scientific discourse, collaboration, and opportunities to mentor the next generation of researchers. Please join more than 4,000 researchers who will be participating in one or more of the 31 conferences this year. We look forward to seeing you! John D. Barnes Interim Executive Director, FASEB SRC Conferences for 2017 Autoimmunity Mechanisms in Plant Development The Biology and Chemistry of Vision Mitochondrial Biogenesis and Dynamics in Health, Disease and Aging The Biology of Cilia and Flagella From Unfolded Proteins in the Endoplasmic Reticulum (ER) to Disease Gastrointestinal Tract XVII: Current Biology of the GI Tract, Mucosa, Microbiota, and Beyond Genetic Recombination and Genome Rearrangements Glucose Transport: Gateway for Metabolic Systems Biology GRKs and Arrestins: From Structure to Disease Growth Hormone/Prolactin Family in Biology and Disease Hematologic Malignancies Ion Channel Regulation Mobile DNA in Mammalian Genomes Molecular Mechanisms of Immune Cell Development and Function Molecular Pathogenesis: Mechanisms of Infectious Disease Molecular, Physiological and Therapeutic Studies of Intestinal Lipid Transport and Metabolism A Multidisciplinary Approach To Addressing Health Disparities and Inequities in the U.S.: Cardiovascular Diseases (NEW) NAD+ Metabolism and Signaling 2017 Origins and Benefits of Biologically Active Components in Human Milk Lysophospholipid and Related Mediators – From Bench to Clinic Polycystic Kidney Disease: Challenges, Differing Viewpoints and Ways Forward Mechanism and Regulation of Prokaryotic Transcription Protein Aggregation in Health and Disease 2 FASEB Science Research Conferences 2017 Protein Kinases and Protein Phosphorylation Protein Lipidation: Enzymology, Signaling and Therapeutics Rapid Signaling and Genomic Steroid Hormone Actions in Health and Disease Regulation and Function of Small GTPases Reversible Acetylation in Health and Disease Signal Transduction in the Immune System TGF-ß Superfamily: Signaling in Development and Disease Register Today! FASEB Science Research Conferences (SRCs) are a continuing series of small, intimate interdisciplinary conferences that explore new approaches in research areas undergoing rapid scientific advances. We invite you to join more than 4,000 fellow attendees at these exciting and engaging conferences exploring and discussing topics in your field. Why Attend ▶▶FASEB offers an all-inclusive registration fee, which includes meals, lodging, and meeting fees. ▶▶All SRCs are organized by leading investigators in their fields of expertise. ▶▶The SRCs spur innovation and the exchange of knowledge. ▶▶The small size of the conference is designed to promote interaction through Poster Sessions, Meet-the-Expert Sessions, and career development workshop. ▶▶The SRCs offer a wide variety of conference topics in the biomedical field across the U.S. and around the world. Pick a Community The SRCs are held annually and are focused on building communities of interest around critical research topics. This encourages collaboration and mentoring. Registration Information Registration Types Single Occupancy: includes a single guest room for one attendee. Double Occupancy with Another Attendee: includes a double occupancy room shared with another paid attendee. Double Occupancy with Guest: includes a double occupancy room shared with your personal invited guest. Guests receive meals, and lodging. Guests may not attend general sessions or poster sessions. Offsite Attendee: The offsite registration fee includes meals and meeting fees. If you choose off-site registration, you are responsible for securing and paying for your lodging, as well as local ground transportation to and from the meeting. Registration Fees ▶▶Registration fees vary depending upon your conference location and registration type. If you register after the early-bird registration deadline, an additional $150 will be added to the registration fee. We Strive For A Diverse Community FASEB, as a longtime recipient organization of federal funding support from the National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) and other federal agencies, has a strong and well documented commitment in helping to inspire and develop a diverse and inclusive biomedical research workforce and community. Career-Oriented Workshops FASEB Science Research Conferences include a biomedical research workforce development workshop and/or a careeroriented workshop for trainees (graduate students, postdoctoral fellows) and earlycareer investigators. These workshops are designed to help prepare trainees and early-career investigators for a variety of career options in the modern biomedical research workforce through broadening their career and skill development outside traditional training. They allow opportunities to promote career/skill development, mentoring, networking, and interaction among the SRC participants. Meet The Expert Sessions FASEB SRCs include Meet-The-Expert sessions for junior investigators. Junior investigators’ work will be presented to allow opportunities for them to promote interaction with more senior participants of the conference. ▶▶Fees cannot be prorated or discounted Poster Sessions for Junior Investigators ▶▶Register early to avoid late fees. Junior investigators' work will be presented to allow opportunities for them to promote interaction with more senior participants. due to contractual arrangements with venues. ▶▶Advanced registration is required. On-site registration is not permitted. Visit Our Website ▶▶Only attendees who have registered and submitted a CV may participate in the conference. ▶▶Abstracts are due at the time of registration, if interested in presenting a poster or short talk. Need help making the case to attend an SRC to your boss? ▶▶Conference registration closes four weeks prior to the start of the conference. See page 5 for registration fees. Visit the Attendee Information page, where you can download a letter to your boss template. Register Now! www.faseb.org/SRC 3 General Information Registration and Payment What does the registration fee include? The single and double occupancy attendee registration fees include five nights of lodging (Sunday through Thursday, with checkout on Friday morning), all meals (five breakfasts, five lunches, and five dinners), and access to all scientific sessions and posters. The off‑site registration fee includes all meals (five breakfasts, five lunches, and five dinners), and access to all scientific sessions and posters. What forms of payment are accepted? FASEB only accepts Visa, MasterCard, and American Express. I cannot stay at the conference for the entire time. Can the registration fee be prorated? FASEB is contractually obligated to pay for five nights of lodging (official conference dates only) at each conference regardless of the number of nights an attendee chooses to stay at the venue. Therefore, registration fees cannot be pro-rated. International Attendees How can I get an official letter of invitation to attend the conference? During the registration process, there is a check box option for a letter of invitation. Mark this box, and a letter of invitation will be sent to you as part of your confirmation materials once your registration and payment have been processed by the online system. Abstracts and Posters Do I have to submit an abstract with my registration? No. Submitting an abstract is optional unless you want to be considered for a poster session or short talk. I need to revise my abstract. Is this possible? Abstracts can be revised and changed until 45 days before the start of your conference. Refer to your registration confirmation email for instructions. Can I register and submit my abstract after the early-bird deadline date? Yes, as long as there is space available at the conference. A late fee of $150.00 will be charged. What is the latest date to submit an abstract? Abstract deadline for inclusion in the program and consideration for a short talk is the last day to register for the conference. See page 5. If I’ve submitted an abstract, will I present a poster? Yes. A poster presentation schedule will be listed in the program provided at the conference. How do I indicate that I want to give a short talk at the conference? When registering select the “short talk” button. Your information will be shared with the conference organizer. The organizer will contact you if you are selected to present your paper. You will also be allowed to present your poster during the poster sessions. Lodging What do single occupancy, double occupancy, and off-site lodging mean? Single occupancy – one (1) registered conference attendee to a guest room. Double occupancy – two (2) registered conference attendees sharing one guest room with two beds. Each attendee pays the double occupancy registration fee. Off-site – the attendee is responsible for arranging for and paying for their own lodging arrangements. I need to arrive a day before the conference starts and/or stay a day after the conference has concluded. How do I make arrangements for the extra night(s)? After you receive your lodging confirmation from FASEB, you must contact the venue directly to make arrangements for the extra nights of lodging. You are responsible for paying for any additional nights. Please note: in Vermont, additional nights at the dorms are not possible. You must make a reservation at a local hotel. Research the city of your conference for additional venue options at www.faseb. org/src. Child and Family Care Resources Are child care and/or family resources are available? FASEB provides detailed information for each conference site on the Science Research Conference (SRC) website and also provides venue information directly to each attendee. Although FASEB does not provide child care services, attendees are welcome to have guests (including spouses, children, nannies and babysitters) accompany them to the conference to provide such care. FASEB offers an alternative off-site registration fee at all conferences, to accommodate those with special family care needs (the off-site 4 FASEB Science Research Conferences 2017 fee includes the conference and all meals but enables attendees to book their own accommodations). Both the FASEB and venue websites include information on nearby off-site accommodations that can assist attendees with locating licensed child care providers and daycare services. The venue management may also provide any assistance to attendees regarding child/family care issues or concerns. Each attendee is also encouraged to contact FASEB with any special needs that they may have. Cancellation What is the cancellation policy? Cancellations received before the cancellation deadline will receive a full refund less a $250.00 cancellation fee. See the cancellation deadline date for your conference. There will be no refunds issued if the cancellation form is received after the cancellation deadline date. I cannot attend the conference; can I send someone in my place? Substitutions are not allowed. Each attendee must register and be approved to attend the conference based on their credentials. Who to Contact FASEB SRC Staff Robin Crawford, CMP Conference Manager [email protected] Kristen Hagy, CMP Conference Manager [email protected] Trina Eacho Conference Coordinator [email protected] Pippa O’Shea Conference Assistant [email protected] Fundraising/Sponsorship Sherri-Gae Scott, Ph.D. Grants Proposal Manager [email protected] Mailing Address FASEB Science Research Conferences 9650 Rockville Pike Bethesda, MD 20814 [email protected] (301) 634-7010 Important Deadlines & Registration Fees Deadlines Conference Dates 2017 Early Bird Registration Deadline Last Day to Register Mitochondrial Biogenesis and Dynamics in Health, Disease and Aging May 21 – 26, 2017 April 20, 2017 April 28, 2017 GRKs and Arrestins: From Structure to Disease June 11 – 16, 2017 May 3, 2017 May 11, 2017 Protein Aggregation in Health and Disease June 11 – 16, 2017 May 3, 2017 May 11, 2017 Rapid Signaling and Genomic Steroid Hormone Actions in Health and Disease June 11 – 16, 2017 May 3, 2017 May 11, 2017 Regulation and Function of Small GTPases June 11 – 16, 2017 May 3, 2017 May 11, 2017 AUGUST JULY JUNE MAY Conference Title Mobile DNA in Mammalian Genomes June 18 – 23, 2017 May 7, 2017 May 18, 2017 From Unfolded Proteins in the Endoplasmic Reticulum (ER) to Disease June 18 – 23, 2017 May 7, 2017 May 18, 2017 Signal Transduction in the Immune System June 18 – 23, 2017 May 7, 2017 May 18, 2017 The Biology and Chemistry of Vision June 25 – 30, 2017 May 14, 2017 May 25, 2017 Mechanism and Regulation of Prokaryotic Transcription June 25 – 30, 2017 May 14, 2017 May 25, 2017 Polycystic Kidney Disease: Challenges, Differing Viewpoints and Ways Forward June 25 – 30, 2017 May 14, 2017 May 25, 2017 Autoimmunity July 9 – 14, 2017 May 28, 2017 June 8, 2017 Ion Channel Regulation July 9 – 14, 2017 May 28, 2017 June 8, 2017 Molecular Pathogenesis: Mechanisms of Infectious Disease July 9 – 14, 2017 May 28, 2017 June 8, 2017 NAD+ Metabolism and Signaling 2017 July 9 – 14, 2017 May 28, 2017 June 8, 2017 TGF-ß Superfamily: Signaling in Development and Disease July 9 – 14, 2017 May 21, 2017 June 8, 2017 The Biology of Cilia and Flagella July 16 – 21, 2017 June 4, 2017 June 15, 2017 Genetic Recombination and Genome Rearrangements July 16 – 21, 2017 June 4, 2017 June 15, 2017 Glucose Transport: Gateway for Metabolic Systems Biology July 16 – 21, 2017 June 4, 2017 June 15, 2017 Origins and Benefits of Biologically Active Components in Human Milk July 16 – 21, 2017 May 28, 2017 June 15, 2017 Protein Lipidation: Enzymology, Signaling and Therapeutics July 16 – 21, 2017 June 4, 2017 June 15, 2017 A Multidisciplinary Approach To Addressing Health Disparities and Inequities in the U.S.: Cardiovascular Diseases (NEW) July 23 – 28, 2017 June 11, 2017 June 22, 2017 Growth Hormone/Prolactin Family in Biology and Disease July 23 – 28, 2017 June 11, 2017 June 22, 2017 Hematologic Malignancies July 23 – 28, 2017 June 11, 2017 June 22, 2017 Molecular, Physiological and Therapeutic Studies of Intestinal Lipid Transport and Metabolism July 23 – 28, 2017 June 11, 2017 June 22, 2017 Gastrointestinal Tract XVII: Current Biology of the GI Tract, Mucosa, Microbiota, and Beyond July 30 – August 4, 2017 June 18, 2017 June 29, 2017 Mechanisms in Plant Development July 30 – August 4, 2017 June 18, 2017 June 29, 2017 Molecular Mechanisms of Immune Cell Development and Function July 30 – August 4, 2017 June 18, 2017 June 29, 2017 Reversible Acetylation in Health and Disease August 6 – 11, 2017 June 25, 2017 July 6, 2017 Protein Kinases and Protein Phosphorylation August 6 – 11, 2017 June 18, 2017 July 6, 2017 Lysophospholipid and Related Mediators – From Bench to Clinic August 20-24, 2017 July 9, 2017 July 20, 2017 Registration Fees (in USD) Conference Location Single Double with Attendee Double with Guest Additional Guest (3rd guest, ages 10 & over) Off-site Attendee Big Sky, MT, Big Sky Resort $1,750 $1,400 $2,240 $840 $1,095 New Orleans, LA, New Orleans Marriott $ 1,800 $ 1,445 $2,460 $1,015 $1,095 Saxtons River, VT, Vermont Academy $ 1,165 $ 1,015 $1,710 $695 $797 Scottsdale, AZ, Scottsdale Plaza Resort $ 1,600 $ 1,400 $2,370 $970 $1,095 Snowmass Village, CO, Base Village Conference Center $ 1,529 $ 1,250 $2,090 $840 $1,095 Steamboat Springs, CO, Steamboat Grand Resort $ 1,400 $ 1,250 $2,150 $900 $1,095 West Palm Beach, FL, Marriott West Palm Beach $ 1,600 $ 1,350 $2,320 $970 $1,095 Cambridge, England, Robinson College $ 1,600 n/a n/a n/a $1,095 Lisbon, Portugal, Marriott Lisbon Hotel $ 1,800 $ 1,530 $2,540 $1,010 $1,095 Register Now! www.faseb.org/SRC 5 2017 Science Research Conferences Autoimmunity July 9 – 14, Saxtons River, VT – Vermont Academy The SRC for Autoimmunity has an uninterrupted tradition of over 20 years and offers a broad overview of recent advances in the field of autoimmunity in a highly interactive environment. Understanding immune tolerance and its breakdown is necessary to treat autoimmune diseases such as lupus, multiple sclerosis, uveitis, type 1 diabetes, arthritis, inflammatory bowel disease, and many others. We bring together basic scientists with clinicians and industry experts to present and discuss new insights into the triggers, pathogenesis and therapy of chronic inflammatory and autoimmune disease. Highlights Important Deadlines ▶▶Career Development Workshop ▶▶Meet-the-Experts sessions ▶▶Short talks selected from Early Bird: May 28, 2017 Eight major sessions will cover a broad range of topics in development, pathogenesis and therapy of autoimmune disease, starting with the effects of genetics and environment, through the role of innate and adaptive immune elements as well as the tissue itself, the role of commensal microbiome and metabolism, and finally translational research and clinical approaches. Each thematic session will feature 4 invited speakers and two talks selected from submitted abstracts. Conference Organizers submitted abstracts Keynote Speakers Christophe Benoist, Harvard Medical School Joe Craft, Yale University Alessandra Pernis, Hospital for Special Surgery Participants have ample opportunity for interaction and discussion. Spontaneous mingling of junior and established scientists will be strengthened by meet-the-speaker sessions that allow discussions of both career issues and science. The intimate atmosphere, strong emphasis on communication and discussion, and a really close interaction between senior and junior scientists makes this conference unique and memorable to participants. Last Day to Register: June 8, 2017 Transportation & Lodging Official Conference Lodging: Vermont Academy, 10 Long Walk, Saxtons River, VT 05154 Airport Information: Vermont Academy in Saxtons River, Vermont is 130 miles from Logan International Airport (BOS) in Boston, Massachusetts and 110 miles from Bradley International Airport (BDL) near Hartford, Connecticut. Register Now! The Biology and Chemistry of Vision June 25 – 30, Steamboat Springs, CO – The Steamboat Grand Hotel This SRC is the only meeting of its kind specifically dedicated to the field of photoreceptor biology. The scientific program reflects the multidisciplinary nature of this field, encompassing classical biochemistry and structural biology as well as modern imaging techniques and molecular therapeutic approaches. Specific session topics will range from photoreceptor physiology and RPE cell biology to the immune respose to photoreceptor degeneration. The scientific program will include two keynote addresses and invited talks, as well as numerous short talks and DataBlitz presentations that will be selected from submitted abstracts. The meeting schedule and venue are designed to present the most exciting scientific advances in an atmosphere that encourages informal interactions and collaborations. All attendees will have the opportunity to present a poster, and additional recreational activities will be available to all participants to foster the exchange of ideas and formulate new collaborations. It is anticipated that there will be funds available to support early career researcher attendance. Highlights Important Deadlines ▶▶Datablitz presentations Early Bird Deadline: May 14, 2017 highlighting presented posters ▶▶Meet-the-Experts sessions ▶▶Career Development Workshop Keynote Speakers Samuel Jacobson, University of Pennsylvania Paul Sieving, National Eye Institute Conference Organizers Marie Burns, UC Davis David S. Williams, UCLA Last Day to Register: May 25, 2017 Transportation & Lodging Official Conference Lodging: The Steamboat Grand Resort, 2300 Mt Werner Cir, Steamboat Springs, CO 80487. Airport Information: The Steamboat Grand Resort is 22 miles from the Steamboat-Yampa Valley Regional/Hayden Airport (HDN) and 155 miles northwest of Denver International Airport (DIA). Parking: Overnight parking fees for summer: $5.00 Ski Time Spare Parking, $10.00, self-parking in hotel underground garage, $15.00 valet. Register Now! 6 FASEB Science Research Conferences 2017 Science Research Conferences 2017 The Biology of Cilia and Flagella July 16 – 21, Scottsdale, AZ – Scottsdale Plaza Resort Research on the biology of the cilium has seen explosive growth as its essential roles in cell signaling and human disease are now well recognized. Sensory cilia act as cellular antennas that transduce key developmental and physiological signals while motile cilia play an essential role in development and organ function. Ciliary diseases or ciliopathies include the most common life-threatening inherited disease of humans, Polycystic Kidney Disease, as well as retinitis pigmentosa, obesity, and mental retardation; all components of the human syndromic pathologies Nephronophthisis, Bardet-Biedl, Meckel Gruber, and Joubert syndromes. Cilia regulate hedgehog signaling, which is essential for development and has been implicated in PKD as well as basal cell carcinomas and other cancers. Despite advances in our understanding of cilia biology, important questions remain about how cilia are assembled, how they function, and how ciliary signal transduction impacts so many developmental events. This SRC provides an intellectual nexus for a broad range of cilia investigators including human geneticists, cell, molecular, and developmental biologists, biochemists, and physician scientists. Cuttingedge research presentations provide a current view of technological advances in ciliary imaging, signal transduction, structural biology, and human disease. The meeting also showcases innovative applications of model organisms, such as Drosophila, C. elegans, and zebrafish for fundemental discovery and high-throughput screening approaches that impact therapeutic assay development. Highlights Important Deadlines ▶▶Meet-the-Experts sessions ▶▶A Biomedical Research Early Bird Deadline: June 4, 2017 Workforce Development Workshop ▶▶Short talks selected from submitted abstracts Keynote Speaker Bradley Yoder, University of Alabama, Birmingham Conference Organizers Iain Drummond, MGH / Harvard Medical School Jagesh Shah, Harvard Medical School Tamara Caspary, Emory University School of Medicine Last Day to Register: June 15, 2017 Transportation & Lodging Official Conference Lodging: Scottsdale Plaza Resort, 7200 North Scottsdale Road, Scottsdale, AZ 85253 Airport Information: The closest airport is the Sky Harbor International Airport (PHX) in Phoenix. The airport is approximately 30 minutes away. The Scottsdale Plaza Resort offers an airport shuttle that runs daily from 5am until 9pm, every 30 minutes. The cost is $23 per person each way. Register Now! From Unfolded Proteins in the Endoplasmic Reticulum (ER) to Disease June 18 – 23, Saxtons River, VT – Vermont Academy This SRC is a unique scientific conference, which focuses on the endoplasmic reticulum (ER) and its functions. The purpose of the meeting is to merge recent developments in molecular biology, cell biology, genetics, and physiology aimed at unraveling the complexities of secretory protein folding, ER stress pathways, lipid signaling, and ER membrane biology, and how failure of these processes lead to pathologies and disease. This meeting will include talks from outstanding scientists, both invited and selected from poster abstracts. The meeting is known for its active discussions, not only during the presentation session, but also during the free afternoons, and especially during the poster sessions. Posters will remain on display during most of the conference and a selection will be advertised in oral poster pitches. The venue, Vermont Academy, is excellently suited for the mingling of junior and established scientists, which will be strengthened by meetthe-speaker sessions that allow discussions of both career issues and science. Highlights Important Deadlines ▶▶Keynote Lecture “Pathophysiology of Protein Folding” ▶▶Poster Flash-Talk Sessions ▶▶Career Development Workshop Keynote Speaker David Ron, Cambridge Institute for Medical Research Ineke Braakman, Utrecht University Conference Organizers Elizabeth Miller, MRC Laboratory of Molecular Biology Reid Gilmore, University of Massachusetts Medical School Early Bird Deadline: May 7, 2017 Last Day to Register: May 18, 2017 Transportation & Lodging Official Conference Lodging: Vermont Academy, 10 Long Walk, Saxtons River, VT 05154 Airport Information: Vermont Academy in Saxtons River, Vermont is 130 miles from Logan International Airport (BOS) in Boston, Massachusetts and 110 miles from Bradley International Airport (BDL) near Hartford, Connecticut. Register Now! Register Now! www.faseb.org/SRC 7 2017 Science Research Conferences Gastrointestinal Tract XVII: Current Biology of the GI Tract, Mucosa, Microbiota and Beyond July 30 – August 4, Steamboat Springs, CO – The Steamboat Grand Hotel This SRC spans the entire range of investigation in gastroenterology, from molecules to cellular interactions to microbiota to intact organisms. It focuses on comparing and contrasting normal biology/physiology with disease pathophysiology and on providing a clinical context for basic research observations. Eight thematic sessions have been organized to encompass rapidly developing areas in GI research: Monitoring and Responding to the Microbiota; Mucosal Injury and Restitution; MicrobiotaHost Crosstalk; Signaling Mechanisms Coordinating Gastrointestinal Homeostasis and Response to Inflammation;) The Stem Cell Niche, Inflammation, and Cancer; Transport and Barrier;) Host-Pathogen Interactions; and Novel Approaches to GI Biology. The format is designed to facilitate the rapid translation of basic biology discoveries into new medically relevant approaches to human disease. In addition to the platform talks from established investigators and early-career rising stars, a number of abstracts from trainees and young investigators will be selected for short talk presentations, and two poster and two oral presentation sessions of rapid-fire “ePoster” presentations will be held to maximize the number of investigators given exposure. Thus, this conference will not only provide a strong overview of cutting edge GI research but also provide a critical venue for trainees and early career investigators to showcase their work. Highlights Important Deadlines ▶▶Career Development Workshop ▶▶Short talks selected from Early Bird Deadline: June 18, 2017 submitted abstracts ▶▶Quick-shot “ePoster” sessions ▶▶Meet-the-Experts sessions Keynote Speaker Ramnik Xavier, Massachusetts General Hospital Conference Organizers Conference Organizers Andrew S. Neish, Emory University School of Medicine Gail A. Hecht, Loyola University Mark R. Frey, University of Southern California and Children’s Hospital Los Angeles Last Day to Register: June 29, 2017 Transportation & Lodging Official Conference Lodging: Steamboat Grand Resort, 2300 Mt Werner Cir, Steamboat Springs, CO 80487. Airport Information: The Steamboat Grand Resort is 22 miles from the Steamboat-Yampa Valley Regional/Hayden Airport (HDN) and 155 miles northwest of Denver International Airport (DIA). Parking: Overnight parking fees for summer: $5.00 Ski Time Spare Parking, $10.00, self-parking in hotel underground garage, $15.00 valet. Register Now! Genetic Recombination and Genome Rearrangements July 16 – 21, Steamboat Springs, CO – The Steamboat Grand Hotel This SRC presents progress in research on diverse aspects of genetic recombination, a critical process that maintains integrity of the genome and that ensures the faithful transmission of the genome between generations. This conference focuses on the study of recombination mechanisms, the impact of recombination on genome integrity, and the influence of other DNA processes on recombination. Many of the recent advances in understanding recombination in normal, pathological, and environmentally stressed contexts have emerged through new combinations of experimental approaches spanning biochemistry, biophysics, genetics, genomics, and cytology. The agenda reflects the diversity of approaches currently used and is specifically geared toward identifying the emerging technologies and concepts that are moving the field forward. The meeting will focus on new, unpublished data in the field and will highlight connections between recombination and other cellular processes, including transcription, replication, cell cycle progression, and other branches of DNA repair. There will be presentations by researchers using diverse model organisms including bacteria, fungi, flies, nematodes, and mammalian cells, as well as in vitro biochemistry and structural biology. The meeting will foster collaboration between researchers worldwide who are interested in the basic and clinical aspects of recombinational repair, particularly in cancer biology. There will be many opportunities for interaction between established investigators and scientists who are new to the field, and a significant number of the plenary speakers will be chosen from submitted abstracts. 8 FASEB Science Research Conferences 2017 Highlights Important Deadlines ▶▶Keynote Address “ Protecting Early Bird Deadline: June 4, 2017 the Genome by Homologous Recombination” ▶▶Career Development Workshop ▶▶Meet-the-Experts sessions Keynote Speakers Maria Jasin, Memorial Sloan Kettering Cancer Center Conference Organizers Tanya Paull, The University of Texas at Austin Scott Keeney, Memorial Sloan Kettering Cancer Center Last Day to Register: June 15, 2017 Transportation & Lodging Official Conference Lodging: Steamboat Grand Resort, 2300 Mt Werner Cir, Steamboat Springs, CO 80487. Airport Information: The Steamboat Grand Resort is 22 miles from the Steamboat-Yampa Valley Regional/Hayden Airport (HDN) and 155 miles northwest of Denver International Airport (DIA). Parking: Overnight parking fees for summer: $5.00 Ski Time Spare Parking, $10.00, self-parking in hotel underground garage, $15.00 valet. Register Now! Science Research Conferences 2017 Glucose Transport: Gateway for Metabolic Systems Biology July 16 – 21, Snowmass, CO – Base Village Conference Center This SRC will provide a lively mix of glucose transporter biology, metabolic regulation, and systems biology methods with multiple lectures featuring disease translational themes. This SRCs was originally launched in the early 1990s in recognition of the cloning and characterization of a subset of the major glucose transporter isoforms. It has continued to feature important advances in glucose transporter biology, but has also evolved to embrace emergent topics in metabolic control mechanisms as related to chronic diseases and conditions such as obesity, diabetes, and cardiovascular disease. Recent progress in this area has been explosive, and this SRC is timely in helping to fully appreciate the significance of recent developments. A particular focus in 2017 will be neuroendocrine regulation of metabolism, liver metabolism, and skeletal muscle metabolism in health and disease, featuring leading scientists in the field along with faculty in the early stages of their careers. The SRC’s themes align well with challenges faced by the pharmaceutical and biotech industries in identifying new therapeutic targets to combat tractable disease mechanisms. The conference has consistently attracted major leaders in these fields as well as emergent young scientists. More than 40 scientists worldwide have been invited to speak at the meeting. A dozen prominent scientists will serve as session chairs and discussion leaders. In addition, approximately 16 junior trainees will present short talks from abstracts. There will also be several poster sessions and an open mike session to present exciting data for discussion. Highlights Important Deadlines ▶▶Career Development Workshop ▶▶Meet-the-Experts sessions ▶▶Short talks selected from Early Bird Deadline: June 4, 2017 submitted abstracts Keynotes Speakers Christopher Newgard, W. David and Sarah W. Stedman Distinguished Professor of Pharmacology and Cancer Biology, Duke University School of Medicine Conference Organizers Ann Louise Olson, University of Oklahoma Health Sciences Center Scott Summers, University of Utah Last Day to Register: June 15, 2017 Transportation & Lodging Official Conference Lodging: Base Village Conference Center, 84 Carriage Way, Snowmass Village, CO 81615. Airport Information: Snowmass Village is just ten miles from the Aspen-Pitkin County Airport (ASE), and 220 miles west of the Denver International Airport (DEN) Register Now! GRKs and Arrestins: From Structure to Disease June 11 – 16, Saxtons River, VT – Vermont Academy This SRC provides an interactive forum to discuss current developments in the G protein-coupled receptor (GPCR) field with a particular focus on GPCR kinases (GRKs) and arrestins. GRKs and arrestins work together to regulate GPCR signaling by reducing the ability of receptors to couple with heterotrimeric G proteins and by targeting active receptors for endocytosis. These mechanisms are important for returning cells to their physiological resting states. In addition, GRKs and arrestins are also thought to initiate alternative signaling pathways and to play prominent roles in addiction, cardiovascular disease and other pathological conditions. Consequently there is a major effort to identify small molecules that bias GPCRs for or against GRK/arrestin-mediated pathways or that prevent overcompensation by GRKs and arrestins. Highlights Important Deadlines ▶▶Keynote Addresses by Nobel Early Bird Deadline: May 3, 2017 The overarching goal of the meeting is to bring together as many scientists working on diverse aspects of GRK/arrestin signaling as possible in order to facilitate the exchange of novel findings and to stimulate the generation of new hypotheses, collaborations, and approaches. The structural and functional mechanisms of GRKs and arrestins, as well as their roles in biased/non-canonical signaling by GPCRs, in the actions of drugs of abuse, in cardiovascular disease and in cancer will be major highlights of the meeting. Sessions devoted to these topics will foster further studies to combat addiction and disease with the ultimate objective of positively influencing human health. There are many opportunities available for attendees to give oral and poster presentations as well as optional recreational activities to foster the exchange of ideas and formulate new collaborations. It is anticipated that there will be some funds available to support attendance by early career researchers. Conference Organizers Laureates Robert J. Lefkowitz and Brian Kobilka ▶▶Career Development Workshop ▶▶Meet-the-Experts sessions Keynote Speakers Robert J. Lefkowitz, Duke University School of Medicine Brian K. Kobilka, Stanford University School of Medicine Jeffrey Benovic, Thomas Jefferson University Federico Mayor, Jr., Universidad Autónoma MadridCentro de Biología Molecular “Severo Ochoa” Last Day to Register: May 11, 2017 Transportation & Lodging Official Conference Lodging: Vermont Academy, 10 Long Walk, Saxtons River, VT 05154 Airport Information: Vermont Academy in Saxtons River, Vermont is 130 miles from Logan International Airport (BOS) in Boston, Massachusetts and 110 miles from Bradley International Airport (BDL) near Hartford, Connecticut. Register Now! Register Now! www.faseb.org/SRC 9 2017 Science Research Conferences Growth Hormone/Prolactin Family in Biology and Disease July 23 – 28, Steamboat Springs, CO – The Steamboat Grand Hotel This SRC will bring together international scientists from academia and industry for lively discussions on the latest developments in the growth hormone (GH)/prolactin (PRL) family of hormones and their clinical applications. Beyond their classic roles in growth and lactation, these related hormones are increasingly recognized regulators of metabolism, stem cells, aging, behavior, cancer, and perinatal health of both mother and child, via actions on diverse target tissues. They also influence major associated health problems, such as obesity, diabetes, aging, mental health and multiple cancers. We will bring together senior and junior investigators working on all aspects of these hormones, from cell biology, genetics, developmental biology, neurobiology, metabolism, physiology, to their clinical and agricultural applications. Together, we will increase our understanding of how GH/PRL family proteins modulate health and disease processes, forge new collaborations, and accelerate the discovery of new pharmacologic approaches. Speakers from the GH/PRL community and related fields from around the world will share breaking data on a variety of cutting edge topics including genetic mutations in synthesis and signaling pathways, newly identified targets, novel mediators and nodes of critical crosstalk with other players, pituitary stem cells, interactions between peripheral hormones, hypothalamus and brain, and new drug targets/pre-clinical studies. Highlights Important Deadlines ▶▶Career Development Workshop ▶▶Invited talks on pioneering Early Bird Deadline: June 11, 2017 investigations of GH/PRL tissue specific actions, mediators, synthesis/secretion innovative therapeutic targets and approaches. ▶▶Short talks selected from submitted abstracts Keynote Speakers Cynthia Kenyon, Calico Labs Conference Organizers Linda Schuler, University of Wisconsin-Madison Rhonda Kineman, University of Illinois at Chicago Last Day to Register: June 22, 2017 Transportation & Lodging Official Conference Lodging: The Steamboat Grand Resort, 2300 Mt Werner Cir, Steamboat Springs, CO 80487. Airport Information: The Steamboat Grand Resort is 22 miles from the Steamboat-Yampa Valley Regional/Hayden Airport (HDN) and 155 miles northwest of Denver International Airport (DIA). Parking: Overnight parking fees for summer: $5.00 Ski Time Spare Parking, $10.00, self-parking in hotel underground garage, $15.00 valet. Trainees are especially welcomed. Many short talks, poster, and travel awards will be selected from submitted abstracts. In addition to a formal “Meet the Experts” session, there also will be many informal opportunities to engage with international leaders in a relaxed setting. This unique opportunity will ensure fruitful discussions, support career mentoring and help to foster new collaborations. Register Now! Hematologic Malignancies July 23 – 28, Saxtons River, VT – Vermont Academy This SRC bring together biochemists, geneticists, molecular biologists, and clinicians interested in the pathophysiology of the leukemias and lymphomas, and the development of novel therapies for these diseases. Leukemia and lymphoma has provided a number of key paradigms for molecularly targeted cancer therapy, as illustrated by the remarkable success of all-trans-retinoic acid for the treatment of acute promyelocytic leukemia and tyrosine kinase inhibitor therapy for chronic myelogenous leukemia. New and promising small-molecule compounds and antibodies targeting epigenetic regulators, surface receptors and downstream signaling pathways are currently under development and will be discussed at this meeting. Added to these examples of targeted therapy, immunotherapy, including checkpoint inhibition and modified T cell-based therapies have emerged as important future anti-leukemia/ lymphoma treatments. The meeting will cover a broad range of topics, including hematopoietic stem cell differentiation, identification and study of novel oncogenes and tumor suppressors, mechanisms of action of products of chromosomal translocations, normal and pathologic signaling in hematopoietic cells, aberrant epigenetic/transcriptional control, genomics of hematological malignancies, the role of tumor microenvironment, and the development of new experimental models of hematologic malignancies. 10 FASEB Science Research Conferences 2017 Highlights Important Deadlines ▶▶Career Development Workshop ▶▶Meet-the-Experts sessions ▶▶Short talks selected from Early Bird Deadline: June 11, 2017 submitted abstracts Keynote Speaker Jay Bradner, Novartis Ari Melnick, Cornell University Conference Organizers Iannis Aifantis, NYU School of Medicine Kimberly Stegmaier, Dana-Farber Cancer Institute Last Day to Register: June 22, 2017 Transportation & Lodging Official Conference Lodging: Vermont Academy, 10 Long Walk, Saxtons River, VT 05154. Airport Information: Vermont Academy in Saxtons River, Vermont is 130 miles from Logan International Airport (BOS) in Boston, Massachusetts and 110 miles from Bradley International Airport (BDL) near Hartford, Connecticut. Register Now! Science Research Conferences 2017 Ion Channel Regulation July 9 – 14, Steamboat Springs, CO – The Steamboat Grand Hotel This SRC will highlight the latest research on mechanisms of ion channel regulation and its impact on the physiology of diverse cell types. It seeks to stimulate discourse, seed new ideas, and facilitate collaboration in ways that will accelerate new discoveries about ion channel regulation at both the basic and translational levels. It will also fuel discovery by bringing together scientists applying all of these diverse technical and conceptual strategies to study ion channel regulation across a range of different biological systems. The program consists of nine scientific sessions and a keynote address, as well as two breakout sessions and lunches focused on trainee career development. Scientific sessions are organized around themes, rather than ion channel subtype, to foster crosstalk between fields, and will cover a variety of topics including sensory systems and pain; regulation of neuronal excitability; regulation of gene expression; ion channels in disease; ion channel structure and drug development; recent advances in imaging and ion channel cell biology; regulation of the cardiovascular system and skeletal muscle; regulation of ER Ca2+ stores and other organelles; celebrating Bill Catterall and ion channels. Presentations in these sessions will be made by both new, up-and-coming investigators as well as established leaders in the ion channel field, including several members of the National Academy of Sciences. Each session will also include two short-talks to be selected from the abstracts, with an emphasis on presentations by graduate students, postdoctoral trainees, and junior faculty. Highlights Important Deadlines ▶▶Special Session: Celebrating Early Bird Deadline: May 28, 2017 William A. Caterall: 40 years of Ion Channel Research ▶▶Career Development Workshop ▶▶Keynote Lecture: Jeanne Nerbonne, Washington University “Diversity in Cardiac Ion Channel Regulatory Mechanisms” Keynote Speaker Jeanne Nerbonne, Washington University Conference Organizers Mark L. Dell’Acqua, University of Colorado School of Medicine James S. Trimmer, University of California, Davis Last Day to Register: June 8, 2017 Transportation & Lodging Official Conference Lodging: Steamboat Grand Resort, 2300 Mt Werner Cir, Steamboat Springs, CO 80487. Airport Information: The Steamboat Grand Resort is 22 miles from the Steamboat-Yampa Valley Regional/Hayden Airport (HDN) and 155 miles northwest of Denver International Airport (DIA). Parking: Overnight parking fees for summer: $5.00 Ski Time Spare Parking, $10.00, self-parking in hotel underground garage, $15.00 valet. Register Now! Lysophospholipid and Related Mediators – From Bench to Clinic August 20-25, New Orleans Marriott, New Orleans, LA This is the leading international conference in lysophospholipid biology, attracting participants from all continents. The focus this SRC is on the physiological and pathophysiological roles of sphingosine 1-phosphate, lysophosphatidic acid and other lysophospholipids. New and established basic scientists, clinical researchers, academics, and industry partners are brought together to share expertise and foster collaboration, thereby accelerating the pace of scientific discovery and facilitating translation from early research to clinical practice. Indeed, the development of Fingolimod, the first oral treatment for multiple sclerosis, is an excellent example of this, as first reported at this conference in 2001. Highlights Important Deadlines ▶▶Keynote Address Early Bird Deadline: July 9, 2017 The conference provides opportunities for substantive interactions between early-stage and established basic, translational and pharmaceutical investigators with an interest in lysophospholipid biology in health and disease. Presentations and posters (with several prizes) will range from molecular aspects of lysophospholipid biology through to emerging therapeutics, genetic and disease models and molecular modelling. Late-breaking scientific advances and junior investigators will feature on the final program, which includes keynote lectures, the Journal of Lipid Research Lectureship and a careers workshop for early career scientists. Junken Aoki, AMED-CREST, Japan Julie Saba, UCSF Benioff Children’s Hospital Oakland, CA “Emerging Roles of Lysophosphatidylserine in Immune System” ▶▶Career Development Workshop focused on early career scientists ▶▶Short talks will be selected from submitted abstracts Keynote Speakers Conference Organizers Susan Pyne, University of Strathclyde Nigel J. Pyne, University of Strathclyde Last Day to Register: July 20, 2017 Transportation & Lodging Official Conference Lodging: New Orleans Marriott, 555 Canal Street, New Orleans, LA 70130 Airport Information: The closest airport is Louis Armstrong New Orleans International Airport (MSY). The airport is approximately 25 minutes away from the Marriott. Please reserve a shuttle beforehand or take a taxi. Parking: Valet parking is available at the hotel for $45.30 per day, limited to one car per guest room. Register Now! Register Now! www.faseb.org/SRC 11 2017 Science Research Conferences Mechanism and Regulation of Prokaryotic Transcription June 25 – 30, Saxtons River, VT – Vermont Academy This SRC will focus on the process of transcription in prokaryotes, from structure/function investigations to transcription networks and system level regulation. In all organisms, controlling the process of transcription is fundamental to gene expression, gene regulation, and development. RNA polymerase, which transcribes genomic DNA into RNA, is the complex protein machine that performs transcription. Additional factors that alter initiation, elongation, or termination of transcription program an amazing variety of developmental pathways. Biochemical and genetic investigations of transcription regulation have a long history of revealing the myriad ways that gene expression can be controlled. Attendees can expect exciting sessions on RNA polymerase structural biology, mechanisms that control initiation, elongation, and termination, regulation of transcription in pathogens, RNA-based control, transcriptional networks, and connections between cell topology and gene expression. Since its inception in 1991, the FASEB conference on Mechanism and Regulation of Prokaryotic Transcription has been held biannually at Vermont Academy in Saxtons River, VT. It is now considered to be the premier meeting in the field of prokaryotic transcription. We are very proud of the fact that there is so much collegiality and a broad age range at this conference. Approximately half of the speakers are chosen from submitted abstracts and the lively poster sessions are always well-attended by all participants. There will be many opportunities for participants to meet new friends and foster new collaborations. Highlights Important Deadlines ▶▶Keynote Address “Regulation of Early Bird Deadline: May 14, 2017 Bacterial Transcription” ▶▶Career Development Workshop ▶▶Lightning round for poster presenters Keynote Speakers Sankar Adhya, National Cancer Institute Joan Conaway, Stowers Institute for Medical Research Conference Organizers Deborah Hinton, National Institutes of Health Elizabeth Campbell, The Rockefeller University Eduardo Groisman, Yale University Last Day to Register: May 25, 2017 Transportation & Lodging Official Conference Lodging: Vermont Academy, 10 Long Walk, Saxtons River, VT 05154 Airport Information: Vermont Academy in Saxtons River, Vermont is 130 miles from Logan International Airport (BOS) in Boston, Massachusetts and 110 miles from Bradley International Airport (BDL) near Hartford, Connecticut. Register Now! Mechanisms in Plant Development July 30 – August 4, Saxtons River, VT – Vermont Academy This SRC is an important and unique conference at the intersection of plant development, signaling, cell biology, modeling and genomics. This conference, which has been held every 2-3 years for the past 2 decades is the only meeting entirely dedicated to plant development. Plant growth and development are at the core of agricultural productivity and important for human survival. In addition, because plants evolved multicellularity independently from animals they provide insight into common and unique solutions to coordination of the behavior of cells and tissues. At this SRC, outstanding researchers from around the world present cutting edge research directed towards understanding how different aspects of plant growth and development are controlled in response to intrinsic and extrinsic cues and how those mechanisms are conserved or modified over evolutionary time. The conference format includes invited speakers and speakers selected from submitted abstracts, lots of time for poster viewing and intensive scientific discussions. Special sessions foster interactions between established scientists and young investigators. The small size of the meeting as well as the secluded location enable discussions of new ideas and emerging concepts in the rapidly moving field of plant development. Highlights Important Deadlines ▶▶Prime international meeting on Early Bird Deadline: June 18, 2017 plant developmental biology for more than two decades ▶▶Outstanding opportunities for students, post doctoral researchers, and early career faculty to discuss their research ▶▶Large number of abstracts selected for short talks in sessions throughout the conference ▶▶Great opportunity to learn more about the newest technologies and interdisciplinary approaches to address questions in developmental biology Last Day to Register: June 29, 2017 Transportation & Lodging Official Conference Lodging: Vermont Academy, 10 Long Walk, Saxtons River, VT 05154 Airport Information: Vermont Academy in Saxtons River, Vermont is 130 miles from Logan International Airport (BOS) in Boston, Massachusetts and 110 miles from Bradley International Airport (BDL) near Hartford, Connecticut. Keynote Speakers Philip Benfey, Duke University Conference Organizers Marja Timmermans, University of Tuebingen Doris Wagner, University of Pennsylvania 12 FASEB Science Research Conferences 2017 Register Now! Science Research Conferences 2017 Mitochondrial Biogenesis and Dynamics in Health, Disease and Aging May 21 – 26, West Palm Beach, FL – The Marriott West Palm Beach The central role of mitochondria in normal cell physiology is evident from human diseases, including metabolic disorders and aging, which are associated with changes in mitochondrial function. This SRC will facilitate an exchange of knowledge and promote collaborative interactions between investigators that study basic aspects of mitochondria with translational investigators engaged in studying mitochondrial roles in human health, human diseases including ageassociated disorders, and the aging process. It will gather basic and translational scientists with a broad range of research interests and different levels of experience ranging from established investigators to graduate students. A collegial format will facilitate discussions between all participants with the goal of bringing together their unique insights and integrate them into this rapidly expanding field. Highlights Important Deadlines ▶▶Collegial format with a unique Early Bird Deadline: April 20, 2017 The major topics covered include 1) mitochondrial gene expression; 2) respiratory chain complex assembly; 3) mitochondrial protein biogenesis and quality control; 4) mitochondrial stress in cell signaling and aging; 5) mitochondrial dynamics in development and disease; 6) mitochondrial dna-driven mechanisms of mitochondrial dysfunction; 7) new pathways, biomarkers and technologies to study mitochondrial function; 8) challenges and opportunities in mitochondrial biology and medicine. Through these topics, the most recent advances in the biology, dynamics and regulation of mitochondria will be discussed and linked with the pathophysiology of mitochondrial disorders and the aging process. Carlos T. Moraes, University of Miami Martin Ott, Stockholm University Eric A. Schon, Columbia University mixture of research into basic molecular mechanisms and applied, translational investigations of human diseases ▶▶Career Development Workshop Keynote Speaker Jodi Nunnari, University of California, Davis Conference Organizers Last Day to Register: April 28, 2017 Transportation & Lodging Official Conference Lodging: Marriott West Palm Beach, 1001 Okeechobee Boulevard, West Palm Beach, FL 33401 Airport Information: Palm Beach International Airport (PBI) is less than 3 miles from the Marriott West Palm Beach. Fort Lauderdale airport (FLL) is one hour away. Parking: Self-parking is $4.00 per day Register Now! Mobile DNA in Mammalian Genomes June 18 – 23, Big Sky, MT – Big Sky Resort This SRC focuses on the dynamic nature of mobile DNAs in mammalian genomes and their phenotypic impacts. Topics will encompass mechanistic and evolutionary aspects of diverse types of retrotransposons, including LINE-1 and endogenous retroviruses, as well as DNA transposons and related human genes. Attendees will also explore interactions between these sequences and the epigenome and endogenous machinery of DNA repair and rearrangement. These elements comprise are a major portion of our DNA, and are significant contributors to genomic diversity in the form of structural variation. While the germ line is a well-known site of activity of mobile genetic elements, there is increasing evidence for expression and mobility in somatic cells and in human diseases, particularly cancers. This makes it an exciting time for the field. Moreover, new insights are being gained into roles of mobile elements in shaping gene regulatory networks in normal cells. Finally, harnessing mobile genetics elements as tools for forward genetic screens or gene delivery has provided new capabilities to change the genome. This is a long standing meeting, certain to be thought provoking, animated, and collegial all at once. Highlights Important Deadlines ▶▶Career Development Workshop Early Bird: June 2, 2017 for early career scientists ▶▶Meet-the-Experts sessions ▶▶Short talks selected from submitted abstracts Conference Organizers Geoff Faulkner, University of Queensland Cedric Feschotte, University of Utah School of Medicine David Ray, Texas Tech University Jose Garcia-Perez, GenyoUniversity of Granada Kathleen Burns, Johns Hopkins University School of Medicine Last Day to Register: June 17, 2017 Transportation & Lodging Official Conference Lodging: Huntley Lodge, Big Sky Resort, 50 Big Sky Resort Road, Big Sky, MT 59716 Airport Information: The closest airport to the Big Sky area is the Bozeman Yellowstone International Airport (BZN). The lodge is approximately one hour from the airport. Register Now! Register Now! www.faseb.org/SRC 13 2017 Science Research Conferences Molecular Mechanisms of Immune Cell Development and Function July 30 – August 4, Snowmass, CO – Base Village Conference Center This SRC focuses on molecular mechanisms underlying fundamental aspects of immune cell biology. The immune system has become an increasingly important model system for understanding information processing by signaling pathways, signal-dependent transcriptional regulation, control of genomic integrity and DNA repair, and principles of development from stem cells. Results from deep analysis of the regulation of lymphocyte development from hematopoietic stem cells link this field to a broad range of hematopoietic, oncological, and developmental mechanisms for which the lymphocyte vantage point can be very illuminating. This SRC is distinctive in its focus on the molecular biology underlying immune responses, including genome-wide insights into regulatory function and dysfunction. It also brings together research on B, T, NK, and innate system immune cells so that shared and contrasting mechanisms can be illuminated, both in the mature effector cells and in their developing precursors. Sessions include (1) early lymphocyte progenitors, (2) mechanisms that underpin lymphocyte development, (3) transcriptional regulation of lymphocyte differentiation, (4) antigen receptor assembly, (5) molecular and physical mechanisms that promote lymphocyte cell fate, (6) b cell activation and neoplasia, (7) the regulation of the immune responses, 8) innate immunity and (9) molecular pathways in innate immunity. The meeting will also include two poster sessions and two workshops consisting of short presentations chosen from submitted abstracts. By highlighting common and contrasting uses of similar mechanisms, the meeting will reveal unexpected synergies between areas of molecular immunology that are traditionally considered distinct. This SRC emphasizes mixing national and international experts with young scientists, including postdoctoral fellows and graduate students, among the presenters in an open atmosphere of scientific exchange. Highlights Important Deadlines ▶▶Keynote address ▶▶Career Development Workshop ▶▶Short talks selected from Early Bird Deadline: June 18, 2017 submitted abstracts Keynote Speaker Dan Littman, New York University Medical School Conference Organizers Cornelis Murre, University of California, San Diego Barbara Kee, University of Chicago David Schatz, Yale University Medical School Last Day to Register: June 29, 2017 Transportation & Lodging Official Conference Lodging: Base Village Conference Center, 84 Carriage Way, Snowmass Village, CO 81615 Airport Information: Snowmass Village is just ten miles from the Aspen-Pitkin County Airport (ASE), and 220 miles west of the Denver International Airport (DEN) Register Now! Molecular Pathogenesis: Mechanisms of Infectious Disease July 9 – 14, Snowmass, CO – Base Village Conference Center Since 1994, this biennial SRC has been devoted to exciting and groundbreaking research on viral, bacterial, fungal, and protozoal pathogens. The combined themes are particularly pertinent regardless of their taxonomic differences as microbes confront similar barriers from the host innate and acquired immune systems, thus indicating both similar and unique virulence strategies. Highlights Important Deadlines ▶▶Career Development Workshop ▶▶Meet-the-Experts sessions ▶▶Short talks selected from Early Bird Deadline: May 28, 2017 To promote multi-disciplinary interactions and collaborations, the sessions are organized by pathogenesis theme, and each includes scientists from a variety of fields. This is the only long-standing specialized international conference that regularly attracts virologists, bacteriologists, mycologists, parasitologists, immunologists, antimicrobial researchers, and translational scientists. Notable speakers include Gordon Dougan, Kim Orth, Vern Carruthers, Erica Ollman Saphire, Gerry Wright, Vanessa Sperandio, Russell Vance, and many others. By convening leading scientists with expertise in all areas of infectious disease, this SRC optimizes information transfer, catalyzes provocative discussions, and fosters long-term cross disciplinary collaborations. The 2017 program will include sessions on diverse aspects of host-microbe interactions from molecular, evolutionary, immunological, and therapeutic perspectives. Talks will also include state-of-the-art approaches as well as how to adapt traditional approaches to meet today’s challenges. Finally, the relatively small meeting size, the diversity of fields, and structured and informal interaction opportunities – including three poster sessions, a formal career development session the final morning of the conference, free time in the afternoon, and Meet the Experts sessions – make this an ideal meeting for young scientists to meet established investigators to develop networks of support that will foster career development. ▶▶Two poster sessions 14 FASEB Science Research Conferences 2017 submitted abstracts Keynote Speaker Mark Heise, The University of North Carolina at Chapel Hill Conference Organizers Erin Gaynor, The University of British Columbia Michael Lorenz, University of Texas McGovern Medical School Last Day to Register: June 8, 2017 Transportation & Lodging Official Conference Lodging: Base Village Conference Center, 84 Carriage Way, Snowmass Village, CO 81615 Airport Information: Snowmass Village is just ten miles from the Aspen-Pitkin County Airport (ASE), and 220 miles west of the Denver International Airport (DEN) Register Now! Science Research Conferences 2017 Molecular, Physiological and Therapeutic Studies of Intestinal Lipid Transport and Metabolism July 23 – 28, Snowmass, CO – Base Village Conference Center Intestinal lipid transport and metabolism is of high interest as deregulation of these pathways can directly contribute to several pathologies such as obesity, cardiovascular disease, and diabetes. Intestinal lipid transport and metabolism remains one of the most dynamic areas in biomedical sciences, for both basic scientific inquiry and translational research. It reaches across the pathogenesis and treatment of major chronic diseases and includes leading-edge scientific technologies in human genomics, proteomics, lipidomics, bioinformatics, systems biology, and new biological model systems. The 2017 SRC will present new knowledge that can ultimately be translated into clinical benefit for millions of patients not adequately addressed by existing therapeutic strategies. It will provide a unique forum for scientists at all levels to enrich their knowledge base, network, and encourage new collaborations and new ideas, thus moving forward the field of lipid sciences. Major conference themes include lipid transfer proteins, systemic metabolism of intestinal lipoproteins, cholesterol metabolism, lipid droplets formation and mobilization, integrative physiological studies of lipids and lipoproteins, intestinal lipid metabolism in other organisms, chylomicron assembly, and enzymes in intestinal lipid synthesis. This SRC provides an international forum of cutting-edge research by graduate students, postdoctoral fellows, and established scientists. A large number of oral presentations will be selected from the abstracts, and the selected talks, poster presentations, and recreational activities will provide students and postdoctoral fellows opportunities to exchange ideas and formulate new collaborations. Highlights Important Deadlines ▶▶Keynote Address: Mansbach Early Bird Deadline: June 11, 2017 Lecture ▶▶Career Development Workshop ▶▶Short talks selected from submitted abstracts Conference Organizers M. Mahmood Hussain, Winthrop University Hospital Kimberly Buhman, Purdue University Gary Lewis, University of Toronto Last Day to Register: June 22, 2017 Transportation & Lodging Official Conference Lodging: Base Village Conference Center, 84 Carriage Way, Snowmass Village, CO 81615 Airport Information: Snowmass Village is just ten miles from the Aspen-Pitkin County Airport (ASE), and 220 miles west of the Denver International Airport (DEN) Register Now! A Multidisciplinary Approach to Addressing Health Disparities and Inequities in the United States: Cardiovascular Diseases NEW! July 23 – 28, Scottsdale, AZ – Scottsdale Plaza Resort This SRC will focus on improving our understanding of the scientific, socioeconomic, clinical, and health policy basis of disparities in cardiovascular health outcomes in the United States, with a view to addressing the challenges posed at every level including complementary and integrative health. Although life expectancy in the United States has increased significantly over the past five decades, key indicators of health outcomes vary markedly by race, ethnicity, sex, socioeconomic status, and geographic location. Cardiovascular disease accounts for more deaths in black and Latino adults than cancer, HIV, and homicide, together. According to the 2013 CDC Health Disparities and Inequalities Report, non-Hispanic black adults are at least 50 percent more likely than their non-Hispanic white counterparts to die prematurely of heart disease or stroke. As a result, health disparities in cardiovascular disease has become an important focus for Congress and the federal government. To draw attention to this issue, this SRC will focus on building a multi-disciplinary approach to addressing health disparities and inequities in the United States. This SRC provides an opportunity for multi-disciplinary teams to develop a roadmap for future discussions on solutions to health disparities/inequities in cardiovascular diseases in the United States. The target audience includes clinicians, health policy makers, epidemiologists, researchers, health educators, trainees at junior faculty, postdoctoral fellows, and graduate students. The conference will include oral, poster, and meet-the-expert sessions and a biomedical research workforce development workshop. Highlights Important Deadlines ▶▶Keynote address: “Historical Early Bird Deadline: June 11, 2017 Perspective on Health Disparities/Inequities in Cardiovascular Diseases in the U.S.” ▶▶Meet-the-Experts sessions ▶▶A Biomedical Research Workforce Development Workshop Keynote Speakers To be announced Conference Organizers Sunny E. Ohia, College of Pharmacy and Health Sciences, Texas Southern University Adebayo Oyekan, College of Pharmacy and Health Sciences, Texas Southern University Last Day to Register: June 22, 2017 Transportation & Lodging Official Conference Lodging: Scottsdale Plaza Resort, 7200 North Scottsdale Road, Scottsdale, AZ 85253 Airport Information: The closest airport is the Sky Harbor International Airport (PHX) in Phoenix. The airport is approximately 30 minutes away. The Scottsdale Plaza Resort offers an airport shuttle that runs daily from 5am until 9pm, every 30 minutes. The cost is $23 per person each way. Register Now! Register Now! www.faseb.org/SRC 15 2017 Science Research Conferences NAD+ Metabolism and Signaling July 9 – 14, New Orleans, LA – New Orleans Marriott NAD and its metabolites are important regulators of cancer, metabolic disease, autoimmunity, and aging. They play important roles in energy metabolism, function as signaling molecules, and as protein modifications such as ADP-ribosylation. This diversity of function demonstrates the biological importance of NAD and the interconnectivity between cellular metabolism, physiology, and cellular signaling. Recently, significant progress has been made in our understanding of NAD that highlight its broad relevance to human health and disease. This meeting brings together all of the leading experts in NAD biology to one venue with the goal of advancing our understanding of the molecule. Experts come from several NAD relevant fields that include Poly-(ADP-ribose) polymerases (PARPs), Sirtuins, NAD dependent signaling networks, calcium signaling, NAD biosynthesis and the chemical biology of NAD. More than 30 scientific leaders from institutions worldwide will present their latest data. In addition, a large number of oral presentations will be selected from submitted abstracts. Selected talks, poster presentations, and recreational activities will provide students and postdoctoral fellows opportunities to exchange ideas and interact with senior colleagues. For the first time, this meeting will be held in the exciting city of New Orleans, an ideal setting to discuss science. Highlights Important Deadlines ▶▶Meet-the-Experts sessions ▶▶Short talks selected from Early Bird Deadline: May 28, 2017 submitted abstracts ▶▶Career Development Workshop Keynote Speaker Vilhelm A. Bohr, NIH Conference Organizers Paul Chang, Ribon Therapeutics Charles Brenner, University of Iowa Lenny Guarente, MIT Anne-Laure Perraud, University of Colorado, Denver Mathias Ziegler, University of Bergen Last Day to Register: June 8, 2017 Transportation & Lodging Official Conference Lodging: New Orleans Marriott, 555 Canal Street, New Orleans, LA 70130 Airport Information: The closest airport is Louis Armstrong New Orleans International Airport (MSY). The airport is approximately 25 minutes away from the Marriott. Please reserve a shuttle beforehand or take a taxi. Parking: Valet parking is available at the hotel for $45.30 per day, limited to one car per guest room. Register Now! Origins and Benefits of Biologically Active Components in Human Milk July 16 – 21, Lisbon, Portugal – Marriott Lisbon Breastfeeding is the normative standard for infant nutrition, and clinical and epidemiological data support clear health benefits for the mother and infant. Public policies have focused on improving rates of breastfeeding globally; however, our understanding of the molecular, chemical, and cellular composition of human milk and its effect on the infant is incomplete. Milk contains more than 700 potentially bioactive constituents comprised of carbohydrates (lactose and human milk oligosaccharidesHMO), proteins, lipids, vitamins, minerals, and others. Technological advancements have made it possible to study many of these milk bioactives. This SRC is the second on this topic and the first outside of the U.S. The 2015 program focused on HMO and microbiota. The 2017 program will additionally include bioactive proteins and lipids, with an emphasis on their effects on cognitive and immune outcomes to the neonate. Sessions will address the interplay between maternal and environmental factors that influence nutrient delivery to the infant pre- and postnatally, as well as developmental programming of infant outcomes during the first 1000 days of life. The conference is specifically designed to foster interactions among established and emerging investigators from all sectors. It will bring together more than 30 invited speakers from across the globe with broad ranges of expertise to share their latest research findings. The keynote lecture will set the stage by reviewing the most recent epidemiological evidence for the health benefits of breastfeeding and current research gaps. 16 FASEB Science Research Conferences 2017 Highlights Important Deadlines ▶▶Career Development Workshop ▶▶Meet-the-Experts Session ▶▶Poster awards and Travel Early Bird Deadline: May 28, 2017 Grants available for trainees Keynote Speakers Lawrence Grummer-Strawn, World Health Organization, Geneva Conference Organizers Sharon Donovan, University of Illinois, Urbana-Champaign Ted Barrett, Lovelace Respiratory Research Institute Kal Ramanujam, Arla Foods Ingredients Last Day to Register: June 15, 2017 Transportation & Lodging Official Conference Lodging: Lisbon Marriott Hotel, Avenida dos Combatentes, Lisboa (Lisbon) Portugal 1600-042 1600-042 Airport Information: The closest airport is the Lisbon Portela Airport (LIS), which is 4.3 miles or 6.9 kilometers from the Lisbon Marriott Hotel. Parking: €19 EUR per day. Register Now! Science Research Conferences 2017 Polycystic Kidney Disease: Challenges, Differing Viewpoints and Ways Forward June 25 – 30, Big Sky, MT – Big Sky Resort This SRC focuses on the autosomal dominant (ADPKD) and recessive (ARPKD) forms of PKD, autosomal dominant polycystic liver diseases with mild or no kidney involvement (ADPLD) and syndromic forms of PKD caused by mutations in genes encoding for proteins in the primary cilium (ciliopathies). It will bring together investigators from a wide range of different research areas sharing an interest on this topic. The conference seeks to 1) to assemble an interdisciplinary program of basic scientists and clinical researchers at the forefront of PKD research to provide a comprehensive update on recent advances in PKD; 2) to provide a format where trainees and junior investigators can present, discuss and learn, with the goal of exciting them about PKD and inspiring them to become the next generation of PKD researchers; 3) to generate discussion to help resolve unanswered questions in PKD and promote collaboration; and 4) to promote the development of novel therapies for PKD by juxtaposing basic scientists, clinical investigators, and representations of the pharmaceutical industry. Eight of the oral presentation sessions are structured around a theme: 1) Genetic mechanisms; 2) Cell biology of PKD proteins, extracellular vesicles and cilia; 3) Epigenetics and microRNAs; 4) Cilia, calcium, and cAMP signaling; 5) Other pathways and model systems; 6) Disease mechanisms in other tissues and organs; 7) Cell metabolism and metabolomics; 8) Biomarkers and clinical trials. A ninth session is reserved for late breaking abstracts. Highlights Important Deadlines ▶▶Keynote Address “Strategies Early Bird Deadline: May 14, 2017 for Kidney Regeneration” ▶▶Special Lecture: Regulatory Path to Drug Approval for Inherited Slowly Progressive Renal Diseases ▶▶Career Development Workshop Keynote Speaker Juan Carlos IzpisuaBelmonte, Salk Institute for Biologic Studies Conference Organizers Vicente Torres, MD, PhD, Mayo Clinic Marie Trudel, PhD, University of Montreal Last Day to Register: May 25, 2017 Transportation & Lodging Official Conference Lodging: Huntley Lodge, Big Sky Resort, 50 Big Sky Resort Road, Big Sky, MT 59716 Airport Information: The closest airport to the Big Sky area is the Bozeman Yellowstone International Airport (BZN). The lodge is approximately one hour from the airport. Register Now! Protein Aggregation in Health and Disease June 11 – 16, Big Sky, MT – The Steamboat Grand Hotel This SRC brings together scientists working on biophysical and biological aspects of protein aggregation and connect physical understand of aggregation to its biological consequences in post mitotic cells. The conference will begin with keynote talks by two leading figures, Dr. Virginia Lee and Dr. Sheena Radford. Their talks will highlight the translational aspects and biophysical underpinnings of protein aggregation. The remainder of the conference will be organized around specific thematic sessions that focus on specific proteins or collections of proteins and work up to uncovering the impact of protein aggregation on cellular processes and disease states. This conference will span a range of topics. These include a discussion of emerging technologies to study protein aggregation in vitro and in cells, advancements in our understanding of cellular stresses induced by protein aggregation, our ability to target the stress response pathways therapeutically as a route to finding cures for devastating neurological and systemic diseases, routes that connect aggregation mechanisms and specific aggregates to disease, methods to target aggregation or particular species in order to cure disease, the emerging synergy between protein aggregation and phase separation in the context of form liquid-like membraneless bodies within cells, and the functional role of protein aggregates, a theme that continues to be paradigm shifting in biology. Taken together these sessions will give the participants an integrative view of protein aggregation and the impact it has on health and disease. The cross-disciplinary nature of the conference is accentuated by the program, which brings together biophysicists, structural biologists, and bioengineers with cell biologists and clinical scientists. Highlights Important Deadlines ▶▶Career Development Panel Early Bird Deadline: May 3, 2017 featuring academic and industry leaders, presenting their thoughts in a Town Hall format. ▶▶Short talks selected from submitted abstracts ▶▶Meet-the-Experts Session Keynote Speaker Virginia Lee, University of Pennsylvania Sheena Radford, University of Leeds Conference Organizers Rohit V. Pappu, Washington University in St. Louis Christina Sigurdson, University of California San Diego Last Day to Register: May 11, 2017 Transportation & Lodging Official Conference Lodging: The Steamboat Grand Resort, 2300 Mt Werner Cir, Steamboat Springs, CO 80487. Airport Information: The Steamboat Grand Resort is 22 miles from the Steamboat-Yampa Valley Regional/Hayden Airport (HDN) and 155 miles northwest of Denver International Airport (DIA). Parking: Overnight parking fees for summer: $5.00 Ski Time Spare Parking, $10.00, self-parking in hotel underground garage, $15.00 valet. Register Now! Register Now! www.faseb.org/SRC 17 2017 Science Research Conferences Protein Kinases and Protein Phosphorylation August 6-11, Robinson College, Cambridge, UK This SRC focuses on the biology of protein kinases and phosphorylation signaling. Among FASEB’s longest-running SRCs, it brings together a dynamic international community of junior investigators, trainees, and established researchers from a field that is achieving startling new insight and medical breakthroughs. The program will link detailed understanding of protein structure and biochemical mechanism to control of large-scale processes like the cell division cycle, cell morphogenesis, and metabolism. This SRC will explore the field’s latest research, which is revealing surprising mechanisms of regulation, previously unappreciated subcellular organization, logic of pathways that coordinate diverse intracellular systems. Importantly, derangement of kinase signaling underlies disease, including cancer and diabetes. Drugs targeting kinases and phosphorylation have achieved dramatic cures and promise more, and the conference has consistently offered a robust platform for clinically important work. To foster international scientific connections the 2017 conference will be held at Cambridge University, a world-class academic research hub with outstanding facilities, recreational options, and social venues. Highlights Important Deadlines ▶▶Career Development Workshop ▶▶Meet-the-Experts sessions ▶▶Short talks selected from Early Bird Deadline: June 18, 2017 submitted abstracts Keynote Speaker Tony Hunter, American Cancer Society Professor, Salk Institute for Biological Studies Conference Organizers Kathryn Ferguson, Department of Pharmacology, Yale University School of Medicine Eric Weiss, Department of Molecular Biosciences, Northwestern University Last Day to Register: July 6, 2017 Transportation & Lodging Official Conference Lodging: Robinson College, Cambridge, Grange Road, Cambridge CB3 9AN, United Kingdom Airport Information: Stansted Airport is approximately 40 minutes by road from Cambridge and Gatwick and Heathrow Airports are about 1.5 - 2 hours by road from the College. Platform and poster sessions will feature insights from structural and biochemical analysis, as well as emerging research in the control of cell division, metabolism, and cell architecture. The meeting will bring together scientists using a wide range of approaches, from structural biology and biochemistry to proteomics, systems biology, and cell biology. In addition to the conference’s traditionally deeply ingrained focus on developing treatments for important human maladies, half of the platform sessions will have an explicit tie to clinical issues: malignancy, cancer, immunity and inflammation, and metabolic disease. Register Now! Protein Lipidation: Enzymology, Signaling and Therapeutics July 16 – 21, Saxtons River, VT – Vermont Academy This SRC will focus on biochemical, structural, and cellular mechanisms of fatty acylation, prenylation, and post-prenylation processing of proteins, emerging therapeutics, the transport of intracellular lipids, and the importance of protein-lipid interactions for cellular signaling at specialized membrane domains and its relevance in disease. This conference is the only international venue where these broad but closely interrelated topics are discussed at length. As the field of protein lipidation has grown over the past 10 years, it has become highly interdisciplinary. This this meeting allows scientists and biomedical researchers from diverse disciplines to come together, discuss new ideas, and form synergistic collaborations. Presentations will highlight progress in our understanding of how lipid-modified proteins promote normal physiological processes, with emphasis on their important roles in major human disorders. Topics will also include emerging drug discovery and development efforts. A significant number of submitted abstracts will be selected for short talks, and awards will be given to the top scientific posters. Research snapshop elevator pitch presentations from graduate students and postdoctoral fellows, a specific Meet-the-Experts session and social activities will allow students and postdoctoral researchers to interact with invited speakers, including industry speakers working in drug discovery, and to form potential new scientific collaborations. 18 FASEB Science Research Conferences 2017 Highlights Important Deadlines ▶▶“Research Snapshot” elevator Early Bird Deadline: June 4, 2017 pitch presentations from graduate students and postdoctoral fellows ▶▶Career Development Workshop ▶▶Meet-the-Experts Sessions Keynote Speaker Gisou Van der Goot, École Polytechnique Fédérale de Lausanne Youla Tsantrisoz, McGill University Conference Organizers Rami Hannoush, Genentech Luke Chamberlain, University of Strathclyde Patrick Casey, Duke University School of Medicine Anant Menon, Weill Cornell Medical College Last Day to Register: June 15, 2017 Transportation & Lodging Official Conference Lodging: Vermont Academy, 10 Long Walk, Saxtons River, VT 05154 Airport Information: Vermont Academy in Saxtons River, Vermont is 130 miles from Logan International Airport (BOS) in Boston, Massachusetts and 110 miles from Bradley International Airport (BDL) near Hartford, Connecticut. Register Now! Science Research Conferences 2017 Rapid Signaling and Genomic Steroid Hormone Actions in Health and Disease June 11 – 16, Snowmass, CO – Base Village Conference Center Steroid hormone action impacts many aspects of physiology and disease states. Although scientists in the field traditionally focused on how nuclear steroid receptors mediate gene transcription, it is now established that these same receptors exist and function at various cellular locations including the cell membrane and mitochondria. Thus, this conference focuses on the latest advances and approaches to understand how signaling from extra-nuclear and nuclear steroid receptors integrate to produce genomic and non-genomic biological effects. The 2017 conference centers on steroid hormone action in cancer, metabolism, neuroscience, cardiovascular effects, ion channels, and lung disease. It will feature many new speakers and provide the opportunity for trainees to present their work in oral and poster sessions. Most importantly, many productive collaborations between scientists, junior and senior, have occurred from the interactions during this meeting. Junior scientists and trainees are especially encouraged to interact with senior faculty, in multiple venues that encourage this during the meeting. Travel funds for trainees are also a priority of this meeting. Highlights Important Deadlines ▶▶Keynote Address “Circadian Early Bird Deadline: May 3, 2017 Metabolism in the Light of Evolution” ▶▶New format: Senior scientist panel discussions following each short talk ▶▶Career Development Workshop Keynote Speaker Mitchell Lazar, University of Pennsylvania School of Medicine Liam Holt, New York University Conference Organizers Carol A. Lange, University of Minnesota School of Medicine Ellis Levin, University of California, Irvine, School of Medicine Don DeFranco, University Of Pittsburgh School of Medicine Stephen Hammes, University of Rochester School of Medicine Last Day to Register: May 11, 2017 Transportation & Lodging Official Conference Lodging: Base Village Conference Center, 84 Carriage Way, Snowmass Village, CO 81615 Airport Information: Snowmass Village is just ten miles from the Aspen-Pitkin County Airport (ASE), and 220 miles west of the Denver International Airport (DEN) Register Now! Regulation and Function of Small GTPases June 11 – 16, West Palm Beach, FL – Marriott West Palm Beach This SRC provides an interactive forum that covers the latest developments in the small GTPase field and presents the newest technological advancements that are being used to unravel the complex roles of small GTPases in human health and disease. Small GTPases (e.g., Ras, Rac, Rho, Cdc42, Rab, Rap, Rheb, and Ral) are essential for key cellular processes such as cell differentiation, proliferation, and migration, as well as the regulation of subcellular events such as vesicle trafficking. These critical functions of small GTPases make them important participants in a wide variety of physiological and pathophysiological processes. The founding member of the small GTPase superfamily, Ras, is the most commonly mutated oncogene in human cancers, and many other small GTPases (including RhoA, Rac1, Rab5, Rheb, and RalA) also play fundamental roles in cancer development and progression. In addition to a strong cancer theme, this SRC will also focus on other biomedically important events, including the promotion of vascular diseases, immunological abnormalities, mental disorders, and metabolic conditions. For these reasons, progress from a number of fields in addition to cancer biology will be highlighted, including neurobiology, developmental biology, computational biology, and membrane biophysics. The meeting seeks to stimulate the cross-pollination of ideas among researchers investigating basic biochemical mechanisms, cell and tissue biology, and translational models to define the diverse functions of small GTPases. Highlights Important Deadlines ▶▶Short talks selected from Early Bird Deadline: May 3, 2017 submitted abstracts ▶▶“Meet-the-Expert” session ▶▶Career-Oriented workshops for trainees and early-career investigators Keynote Speaker Allan Balmain, University of California San Francisco Helen Diller Family Comprehensive Cancer Center Conference Organizers Carol Williams, Medical College of Wisconsin, Milwaukee Angeliki Malliri, Cancer Research UK Manchester Institute Last Day to Register: May 11, 2017 Transportation & Lodging Official Conference Lodging: Marriott West Palm Beach, 1001 Okeechobee Boulevard, West Palm Beach, FL 33401 Airport Information: Palm Beach International Airport (PBI) is less than 3 miles from the Marriott West Palm Beach. Fort Lauderdale airport (FLL) is one hour away. Parking: Self-parking is $4.00 per day. Register Now! Register Now! www.faseb.org/SRC 19 2017 Science Research Conferences Reversible Acetylation in Health and Disease August 6 – 11, Big Sky, MT – Big Sky Resort Over the past few years, the “epigenetic” regulation of the genome has become increasingly important to understanding both the etiology and fundamental mechanisms of aging and age-related diseases. Key to epigenetic regulation are two classes of lysine-modifying enzymes, the histone deacetylases (sirtuins and HDACs) and the histone acetyltransferases (HATs). This SRC is the only conference dedicated to protein acetylation, and will bring together leaders in the field to exchange exciting new fundamental discoveries such as new lysine post-translational modifications (e.g. 3-hydroxybutyryl lysine and palmitoyl lysine) and the how these modifications can regulate transcription, cell signaling, and protein secretion. A primary objective of the conference is to transfer knowledge and foster collaboration between basic academic researchers, clinical scientists, and industrial researchers to understand how lysine acetylation controls human health and how to prevent and treat a diverse set of agerelated diseases that could extend human healthspan and lifespan. A second objective is to foster the development and interests of younger investigators to help support their career development. This meeting is particularly timely because recent development on bromodomain inhibitors is continuing to generate a lot of interests and more clinical data on small molecule modulators of sirtuins and HDACs are being generated. Highlights Important Deadlines ▶▶Keynote Address “Mechanisms Early Bird Deadline: June 25, 2017 Involved In Cooperative Functions Of Histone Acetyltransferases” ▶▶Panel discussion: Terry Sheppard (Nat. Chem. Biol. Editor), Philip Cole, James Ellis (GSK), Lisa Monteggia “Career Choices” ▶▶Meet- the-Experts sessions Keynote Speakers Robert Roeder, The Rockefeller University David Sinclair, Harvard University Last Day to Register: July 6, 2017 Transportation & Lodging Official Conference Lodging: Huntley Lodge, Big Sky Resort, 50 Big Sky Resort Road, Big Sky, MT 59716 Airport Information: The closest airport to the Big Sky area is the Bozeman Yellowstone International Airport (BZN). The lodge is approximately one hour from the airport. Conference Organizers Li-Huei Tsai, Massachusetts Institute of Technology Hening Lin, Cornell University and HHMI Yingming Zhao, The University of Chicago Register Now! Signal Transduction in the Immune System June 18 – 23, Snowmass, CO – Base Village Conference Center This SRC focuses on the most recent advances in the fields of signal transduction in the immune system, with an emphasis on the coupling of signaling to differentiation pathways, the development of new technologies for understanding and imaging signaling, interactions between metabolism and lymphocyte activation and differentiation, signaling through mechanotransduction, and signaling through immunomodulatory receptors in cancer. These topics have direct relevance to a number of clinically important areas, including autoimmunity, immunodeficiency diseases, transplantation immunology, tumor immunology, infectious diseases and chronic inflammation. In particular, leukocyte metabolism, the mechanism and feedback of antigen receptor signaling initiation and kinase regulation, immunomodulatory receptors, and cytoskeletal changes that accompany leukocyte activation and migration have provided a wealth of new information that will enhance our understanding of the complex pathways that control immune responses under normal as well as pathogenic situations. As such, the mechanisms and pathways that will be discussed in detail at this conference represent a major source of target leads for the development of new therapeutics to treat immunological disorders and sit at the forefront and intersection of basic and translational research. There will also be sessions that bridge these two types of research. The 2017 meeting is the 9th on the series and features speakers from around the world who will discuss cutting-edge research in the area of immune cell signaling. 20 FASEB Science Research Conferences 2017 Highlights Important Deadlines ▶▶Career Development Workshop ▶▶Meet-the-Experts sessions ▶▶Short talks selected from Early Bird Deadline: May 7, 2017 submitted abstracts Keynote Speaker Doreen Cantrell, University of Dundee Conference Organizers Daniel D. Billadeau, Mayo Clinic Art Weiss, University of California, San Francisco Janis K. Burkhardt, University of Pennsylvania Morgan Huse, Memorial Sloan Kettering Cancer Center Last Day to Register: May 18, 2017 Transportation & Lodging Official Conference Lodging: Base Village Conference Center, 84 Carriage Way, Snowmass Village, CO 81615 Airport Information: Snowmass Village is just ten miles from the Aspen-Pitkin County Airport (ASE), and 220 miles west of the Denver International Airport (DEN) Register Now! Science Research Conferences 2017 TGF-ß Superfamily: Signaling in Development and Disease July 9 – 14, Lisbon, Portugal – Marriott Lisbon This SRC is an important and unique scientific conference where the pivotal role of TGF-β family members, including TGF-βs, nodal, activins, BMPs, and GDFs, in developmental, homeostatic, and pathological processes is explored through formal talks, poster sessions, and interactive and intensive scientific discussion sessions. This field is expanding into previously uncharted areas of biology and human pathogenesis. Program topics include tissue morphogenesis in development and disease, signaling networks and crosstalk, inflammation, vasculature and tissue transformation, tissue microenvironment dynamics in disease, therapeutic frontiers of TGF-β signaling, and homeostatic and metabolic control of growth and disease. This meeting includes researchers from around the world presenting diverse, cutting edge and forward looking research directed towards a fundamental understanding of the mechanisms of TGF-β family signaling: how these factors mediate context- and temporalspecific signals to orchestrate complex developmental processes, how aberrations in this signaling pathway lead to developmental abnormalities and human disease pathologies, and how this knowledge may come to be applied in the clinic. All lectures will be held in an intimate setting with a limited number of participants that is an ideal setting especially for young students and trainees and those who recently entered the TGF-β world to engage into a discussion with world-renowned experts. Speakers are encouraged to present and discuss unpublished data. This meeting brings together a diverse group of cell biologists, developmental biologist, embryologist, biochemists, physiologists, biophysicists, and translational biologists to share the latest developments in different fields. Highlights Important Deadlines ▶▶Keynote Lecture Early Bird Deadline: May 21, 2017 “Developmental syndromes and genetic alterations in the TGF-β pathway” ▶▶Career Development Workshop ▶▶Meet-the-Experts sessions Keynote Speaker Harry C. Dietz, Institute of Genetic Medicine, Investigator, Howard Hughes Medical Institute, Director, Smilow Center for Marfan Syndrome Research , Johns Hopkins University School of Medicine Last Day to Register: June 8, 2017 Transportation & Lodging Official Conference Lodging: Lisbon Marriott Hotel, Avenida dos Combatentes, Lisboa (Lisbon) Portugal 1600-042 Airport Information: The closest airport is the Lisbon Portela Airport (LIS), which is 4.3 miles or 6.9 kilometers from the Lisbon Marriott Hotel. Parking: €19 EUR per day Conference Organizers Akiko Hata, Cardiovascular Research Institute, University of California, San Francisco Mary Mullins, University of Pennsylvania Perelman School of Medicine Register Now! Register Now! www.faseb.org/SRC 21 www.faseb.org/SRC Coming Up in 2018! As of 2/14/17, subject to change Biological Methylation: Fundamental Mechanisms in Human Health and Disease The Hilton Florence Metropole, Florence, Italy June 17 – 22 Calcium and Cell Function Granlibbaken Tahoe, Tahoe City, CA June 10 – 15 Cell Signaling in Cancer: From Mechanisms to Therapy The Steamboat Grand, Steamboat Springs, CO June 3 – 8 COAST 2018 The Plaza Scottsdale Resort, Scottsdale, AZ September 12 – 16 Cross Translational Research in Fibrosis Across Organs The Plaza Scottsdale Resort, Scottsdale, AZ September 30 – October 5 Dynamic DNA Structures in Biology St. Bonaventure University, Olean, NY July 15 – 20 Folic Acid, Vitamin B12 and One-Carbon Metabolism The Atlantica, Oak Island Resort & Conference Center July 29 – August 3 Functional Disulfide Bonds in Health and Disease The National Conference Center, Leesburg, VA June 17 – 22 Fundamental Biology and Pathophysiology of the Liver The Plaza Scottsdale Resort, Scottsdale, AZ June 10 – 15 Genome Engineering: Cutting-Edge Research and Applications The Hilton Florence Metropole, Florence, Italy June 24 – 29 Immunological Aspects of Metabolic Syndrome Base Village Conference Center, Snowmass, CO August 12 – 17 Immunoreceptors and Immunotherapy Base Village Conference Center, Snowmass, CO June 10 – 15 Lipid Droplets on the Move from Health and Disease The Steamboat Grand, Steamboat Springs, CO June 24 – 29 Machines on Genes Base Village Conference Center, Snowmass, CO June 24 – 29 Microbial Glycobiology The Plaza Scottsdale Resort, Scottsdale, AZ June 17 – 22 Molecular Biophysics of Membranes St. Bonaventure University, Olean, NY June 17 – 22 Nutrient Sensing and Metabolic Signaling Base Village Conference Center, Snowmass, CO August 5 – 10 Nutritional Immunology and the Microbiota: Rules of Engagement in Health and Disease The National Conference Center, Leesburg, VA June 24 – 29 Phospholipids: Dynamic Lipid Signaling in Health and Disease The Steamboat Grand, Steamboat Springs, CO July 29 – August 3 Post Transcriptional Control of Gene Expression: Mechanisms of RNA Decay The Plaza Scottsdale Resort, Scottsdale, AZ June 24 – 29 Protein Folding in the Cell St. Bonaventure University, Olean, NY July 22 – 27 Protein Phosphatases Base Village Conference Center, Snowmass, CO July 15 – 20 Protein Phosphorylation Networks in Health and Disease Base Village Conference Center, Snowmass, CO July 22 – 27 Retinal Neurobiology and Visual Processing St. Bonaventure University, Olean, NY June 24 – 29 Skeletal Muscle Satellite Cells and Regeneration The Steamboat Grand, Steamboat Springs, CO July 8 – 13 Small GTPases in Membrane processes: Trafficking, Autophagy, and Disease The National Conference Center, Leesburg, VA September 23 – 28 The 4th International Conference on Retinoids The Steamboat Grand, Steamboat Springs, CO June 10 – 15 The Lung Epithelium in Health and Disease The National Conference Center, Leesburg, VA July 29 – August 3 Trace Elements in Biology and Medicine Granlibbaken Tahoe, Tahoe City, CA June 3 – 8 Transcription, Chromatin and Epigenetics The Hilton Florence Metropole, Florence, Italy September 16 – 21 Translational Neuroimmunology Base Village Conference Center, Snowmass, CO July 8 – 13 Ubiquitin and Cellular Regulation Base Village Conference Center, Snowmass, CO June 17 – 22 Virus Structure and Assembly The Steamboat Grand, Steamboat Springs, CO July 22 – 27 Yeast Chromosome Biology and Cell Cycle The Steamboat Grand, Steamboat Springs, CO July 15 – 22 22 FASEB Science Research Conferences 2017 Science Research Conferences 2017 •Engage• ore C l p rc w .f /s ww Organize a FASEB SRC. Organizing meetings is a community responsibility. It fosters team building and provides a valuable learning experience. If you are a science professional holding an advanced medical or doctoral degree and are active in scientific research, you may submit a proposal to organize a conference with FASEB. Thank you! te tribu on Do you have a passion for your scientific field? Learn•E x Organize! aseb.org Learn. FASEB SRCs provide ample networking opportunities for both seasoned scientists and junior investigators, as attendees are encouraged to present posters and short talks, eat meals together, and converse with leaders in the field during Meet-the-Expert Sessions. Explore. To submit a proposal, please email [email protected] to request an application. Write “Proposal Application” and the year of the proposed conference in the subject line of the email. FASEB is currently accepting 2019 conference proposals until Monday, September 26, 2017. For more information, visit www.faseb.org/src. Engage. FASEB SRCs encourage dialogue among prominent scientists, faculty, postdoctoral fellows and graduate students who are working in areas experiencing rapid scientific advances and conducting cutting-edge research. Meetings are traditionally small, averaging between 100 and150 participants, and held over five days. Contribute. FASEB SRCs are organized by leading investigators in their fields of expertise. Biolegend Bright Foundation, The Edward P. Evans Foundation Gabrielle’s Angel Foundation for Cancer Research Ipsen Bioscience Kadmon Corporation, LLC The Pershing Square Foundation Regeneron Pharmaceuticals Inc. GOLD Acceleron Pharma, Inc. Antibodies Incorporated Avanti Polar Lipids, Inc Cydan Development. Inc. Danone Janssen RnD, LLC (Johnson&Johnson) Kevin Turner March of Dimes Mead Johnson & Company, LLC (MJN) Paul J. Davis, MD Pfizer, Inc. Pliant Therapeutics, Inc. Plum Foundation, The Public Library Service (PLOS) Rebiotix, Inc. Regulus Therapeutics Inc Scholar Rock, Inc. SILVER AbbVie Inc. Biolegend BrighFocus Foundation Calico Life Science DaVita (Total Renal Care, Inc.) Duke-NUS Genentech, Inc Genentech, Inc Growth Hormone Research Society Immune Design Corp Jae Joung Novartis Institutes of Biomedical Research, Inc. ▶▶Option to display a table-top exhibit at the sponsored conference ▶▶One (1) complimentary single occupancy registration ▶▶Company logo in the program ▶▶Logo and link to your company on the FASEB SRC web page ▶▶Distribution of company brochure at the sponsored conference GOLD LEVEL $5,000 - $9,999 ▶▶One (1) complimentary single occupancy registration ▶▶Company logo in the program ▶▶Logo and link to your company on the FASEB SRC web page ▶▶Distribution of company brochure at the sponsored conference SILVER LEVEL $2,000 - $4,999 ▶▶Company logo in the program ▶▶Logo and link to your company on the FASEB SRC web page ▶▶Distribution of company brochure at the sponsored conference Current Sponsors 2017 PLATINUM PLATINUM LEVEL $10,000 or more Research and Diagnostic Systems, Inc Richard G. Brennan Tishcon Corp University of California (CBHA) University of Oklahoma Foundation (Harold Hamm Diabetes Center) BRONZE LEVEL $1,999 OR LESS ▶▶Company logo in the program ▶▶Distribution of company brochure at the sponsored conference BRONZE Company of Biologists (JCS) Edison Pharmaceuticals, Inc. Enzo Life Sciences, Inc. Mebias Discovery LLC Metabolic Solutions Development Co LLC New England BioLabs, Inc. Ono Pharmaceuticals Penn State Center for RNA Molecular Biology (CRMB) The Rockerfeller University (Journal of Cell Biology) If you are interested in providing support please contact: Sherri-Gae Scott, Ph.D., Grants Proposal Manager, [email protected] Register Now! www.faseb.org/SRC 23 Wednesday, September 27, 2017 We invite you to submit a proposal for consideration. For additional information and submission guidelines, visit www.faseb.org/SRC and click on Organize an SRC. FASEB SRCs are organized by leading biomedical researchers in their field. Conferences are organized to present and discuss new and innovative research in those areas undergoing rapid scientific advances. Conferences are held in both U.S. and international locations. The FASEB Science Research Conferences Advisory Committee reviews and selects conferences from submitted proposals. Organizers are not required to be affiliated with FASEB to submit a proposal. All conferences are scheduled two years in advance. Organizers are responsible for assembling the scientific content of the conference. Upon conference acceptance by FASEB, full-time SRC staff assist organizers with sponsorship and conference logistics. Join the FASEB SRC program and expand and shape the direction of research in your community. www.faseb.org/SRC rc Learn•E x Submission deadline for 2019 conferences: w .f /s Organizing meetings is a community responsibility, providing valuable learning experiences and fostering team building, which helps to promote your career. If you are a science professional holding an advanced medical or doctoral degree and are active in scientific research, you may submit a proposal to organize a conference with FASEB. ww Organize a FASEB SRC te tribu on Call for 2019 Conference Proposals e•Engage•C r o pl aseb.org
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