Science 7 Standard 4 08-06 8/22/02 7:49 AM Page 139 Standard Indicator 7.4.4 Cell Cycle Purpose Students will explain that cells continually divide to make more cells for growth and repair. Materials For the teacher: long balloon, water, confetti or some other small objects that represent organelles, transparency of Black Line Master (BLM) Cell Division, overhead projector For each student: copy of BLM Cell Division For each pair of students: various craft materials to model the cell cycle, such as pipe cleaners for chromosomes, string for spindle fibers, etc. incorporating TECHNOLOGY Direct students to the Cells Alive! Web site to view a video clip and animation of mitosis in an animal cell: www.cellsalive.com/ mitosis.htm. Activity extending THE B. Pre-Activity Discussion 1. Direct students to roll their shirt sleeves and rub their hands a few times across the skin on their arms. 2. Tell students that they are wiping off millions of dead skin cells as they rub their arms. 3. Ask students: “If you are wiping off millions of dead skin cells, why does your skin look the same and why do you not ‘run out’ of skin cells?” 4. Discuss students’ explanations and explain that cells continually divide to make more cells for growth and repair of skin and other organs and tissues. Explain that the entire process of cell growth, formation, and division is called the cell cycle. 5. Explain that most human cells divide in a process called mitosis. 6. Ask students to give other examples of evidence of growth and repair (e.g., healing a cut in the skin, growth stages to adulthood, etc.). Have students research how cancer cells behave and ask them to relate it to mitosis and the cell cycle. ACTIVITY C. Activity 1. Show the balloon to the class and explain that it is a model of a cell. Ask students: “How do you think animal cells divide?” (continued) Standard 4 / Activity 2 Indiana Science Grade 7 Curriculum Framework, October 2002 Standards Links 7.4.1, 7.7.2 page 139 Standard 4 A. Pre-Activity Preparation Fill a long balloon with water and confetti and seal the balloon. Science 7 Standard 4 08-06 8/22/02 7:49 AM Page 140 Activity (continued) 2. Twist the balloon into two parts; be sure organelles are included on both sides. 3. Explain that as the cell divides, each new cell receives organelles and a copy of genetic information in the form of chromosomes from the parent cell. 4. Ask students: “Why is it important that the new cells receive a copy of the genetic information?” 5. Discuss how chromosomes contain all of the instructions for the cell’s function and growth. D. Cell Cycle and Mitosis 1. Show the transparency of the BLM Cell Division on the overhead and distribute a copy of the BLM to each student. 2. Explain to students that scientists have identified six basic steps in the cell cycle. 3. Point out each stage on the transparency as you explain the cell cycle. Explain that after the two daughter cells form, the cycle begins again. 4. Have students review the cycle on their own copies of the BLM. Standard 4 E. Model It! 1. Divide students into pairs, distribute craft materials, and ask: “How could you make a model showing the cell cycle?” 2. Monitor and guide students as they work. Ask questions such as: “Why do cells go through mitosis? Why is it so important for the genetic material/chromosomes to be copied to all daughter cells?” 3. Have each pair of students share their models with the class. Classroom Assessment Basic Concepts and Processes At the end of the activity, ask questions, such as the following: Why do cells continually divide and what is the name of this process? How do you know that when you get a cut, your skin will grow back and heal? page 140 Standard 4 / Activity 2 Indiana Science Grade 7 Curriculum Framework, October 2002 Standard 4 / Activity 2 Indiana Science Grade 7 Curriculum Framework, October 2002 CYTOKINESIS The cell membrane pinches in around the middle of the cell. Each daughter cell ends up with the same number of identical chromosomes. TELOPHASE The chromosomes relax. A membrane forms around each region of chromosomes. genetic material daughter chromosome ANAPHASE The chromosomes pull apart and the daughter chromosomes move to opposite ends of the cell. daughter chromosome METAPHASE The chromosomes are pulled by spindle fibers to line up across the middle of the cell. 7:49 AM PROPHASE - The genetic material “shrinks” or condenses to form chromosomes. Spindle fibers form a bridge between the ends of the cell and each chromosome attaches to a spindle fiber. replicated chromosomes (sister chromatids) spindle fibers 8/22/02 nuclear membrane INTERPHASE - The cell grows to its mature size and makes a copy of its genetic material and other cell parts. Cell Division Name: Science 7 Standard 4 08-06 Page 141 Black Line Master 1 page 141 Science 7 Standard 4 08-06 8/22/02 7:49 AM Page 142 Cell Division Teacher Directions Make a transparency copy of the BLM Cell Division and distribute a copy of the BLM to each student in the class. Go through each stage in the cell cycle, pointing to the diagrams on the transparency. Have students review the cell cycle while looking through their own copies of the BLM. Divide students into pairs and distribute craft materials. Direct them to use the craft materials to model the cell cycle. Answer Key Not applicable. Black Line Master 1 page 142 Standard 4 / Activity 2 Indiana Science Grade 7 Curriculum Framework, October 2002
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