TABLE OF CONTENTS The Cytoskeleton: Structure and Function During Spaceflight The Cytoskeleton in Spaceflown Cells: An Overview Marian Lewis…………………………………………………………………………………………………..………………..1 Gravity Dependence of Microtubule Self-Organisation James Tabony…………………………………………………………………………………………………………………..13 Effect of Gravity Changes on the Cytoskeleton in Human Lymphocytes Marianne Cogoli-Greuter………………………………………………………………………………………….…………..27 Actin-Cytoskeletal Control of Gravity Sensing and Gravity-Oriented Tip Growth Markus Braun, Brigitte Buchen and Andreas Sievers ……………………………………………………………….………..39 Biopolymer Networks and Cellular Mechanosensing Paul Janmey, Penelope C. Georges, Oliver Wagner, Tony Yeung………………………………………………………….....45 Gravitational Influence on Biomolecular Engineering Processes Gravitational Influence on Biomolecular Engineering Processes David Klaus …………………………………………………………………………………………………………………...51 Tissue Engineering of Cardiac and Skeletal Muscle: Lessons Learned from Micropatterned Collagen and Microgravity Louis Terracio, Wentao Yan, Robert Price, Michael Yost, David G. Simpson……………………………………………….67 Transcription Factor Translocation during Changes in Renal Cell Mechanical Culture. Timothy G. Hammond, Luis Cubano, Patricia L. Allen, Louis Stodieck, John Genova, R.B. Bryan Klassen, John Love………………………………………………………………………………..75 Molecular Therapies for Disuse Osteoporosis Ted Bateman…………………………………………………………………………………………………..………………83 Astrobiology: Life in a Planetary Context Planet Formation Alan Boss………………………………………………………………………………………………………….…………..91 The NASA Astrobiology Institute: Revealing Life in a Planetary Context Rosalind A. Grymes and Edward Goolish…………………………………………………………….………………………99 Systems and Evolutionary Biology (2001 Symposia) Signaling Molecules in the HYDRA Head Organizer and the Evolution of Axis Formation Bert Hobmayer, Fabian Rentzsch, Ulrich Technau, Thomas W. Holstein……………………………………………………107 Magnetism and Biology: The Magnetotactic Bacteria D.A. Bazylinski…………………………………………………………………………………………..……………………115 Approaches to Understanding the Origin and Early Evolution of Plant Body Symmetry and Gravity Responses Linda E. Graham and Martha E. Cook ……………………………………………………………………..………………..127 Plant Body Plans: Unity of Type or Conditions of Existence? Karl J. Niklas……….…………………………………………………………………………………………………………133 Gravitational and Space Biology Bulletin 17(2), June 2004 iii
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