DO NOT WRITE ON THIS PAGE Go to http://learn.genetics.utah.edu/ Read the directions carefully to make sure you are in the correct section of the site! Start by clicking Tour of Basic Genetics under the heading Genetics. Click What is DNA? 1. Why is DNA called a blueprint? __________________________________________________________________ 2. The “twisted ladder” shape of the DNA molecule is called a ____________________________. 3. Name the four bases found in a DNA molecule: _____________________________________________________ 4. A DNA strand is made of ___________________ which make up _______________ which make up sentences. 5. These “sentences” are called ___________________. Click What is a Gene? 6. Genes are ______________________ for building all the _____________________that make our body function. 7. What are genes made of? _________________________________ 8. How many genes do you have? _____________________________ 9. When a gene is changed, it is said to be _______________________. 10. A mutation in the hemoglobin gene causes which disorder? ________________________________ Click What is a Protein? 11. Proteins are the ________________ that make all living things _______________________. 12. How are proteins like the parts of a car? __________________________________________________________ 13. ____________________ proteins are responsible for picking up the signal and passing it to the next cell. 14. How do structural proteins help cells? ____________________________________________________________ 15. Each gene in DNA encodes information on how to make ____________________________________________. 16. What is the form of the DNA’s message to make protein? ____________________________________________ 17. Where does the message from the nucleus go? ____________________________________________________ 18. What reads the message to make the protein? ____________________________________________________ **When you are finished with these to activities, click Home in the upper left corner, to return to the original menu.** Go to Molecules of Inheritance > Central Dogma > Transcribe and Translate a Gene * Scroll Down and READ the screen to find #19-23 BEFORE doing the activity!!* 19. Read the information about transcription. Briefly summarize what is happening in transcription. ___________________________________________________________________________________________ 20. Read the information about translation. Briefly summarize what is happening in translation. ___________________________________________________________________________________________ 21. How are the bases in mRNA different from DNA? ___________________________________________________ 22. What codon starts translation? __________________________________________________________________ 23. When does translation stop? ____________________________________________________________________ 24. Scroll back to the top of the screen. Follow the instructions for the activity. Start reading where it says “The colored boxes above represent…” Complete the Diagram as you complete the activity: Circle the start codon! DO NOT start translating into amino acids until you reach the start codon! DNA: DNA: T A A T G C T A G A C G T G T T C T A G G A A T T A C G A T C T G C A C A A G A T C C T (the other side of the strand): Transcribe into mRNA: __________________________________________________________ (the letters you type in) Translate into Amino Acids: ______________________________________________________ (you drag these in from the table) Go back to Central Dogma and select What Makes a Firefly Glow? 25. What is luciferase? ____________________________________________________________ (RECALL: enzymes are special types of proteins) 26. What enzyme does the actual transcription of luciferase? _________________________________ 27. Where does the mRNA move to when transcription is complete? ____________________________ 28. What goes into the ribosome? ____________________ What comes out?______________________ 29. What molecules that we read about are missing from the animation? _________________________ (These are the ones that bring the amino acids to the ribosome.) 30. What are proteins made of? ____________________________________________ 31. What are two reasons that fireflies glow? ____________________________________________________ ____________________________________________________________________________________ 32. How can a firefly that has a mutated luciferous enzyme still survive? ____________________________________________________________________________________ ____________________________________________________________________________________
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