Health 125
Global Health & Wellness
Your Health & Wellness
Course Materials
Reference Biology: Concepts & Connections 5th
Textbooks: ed. by Campbell et al.
Understanding Nutrition 11th ed. By
Whitney & Rolfes
Focus on Health 7th ed. By Hahn et
al.
Required Mountains Beyond Mountains by
Book: Tracy Kidder
Lectures/Lab: M-F, 8-8:50am in SAM 203
Course information:
Website: http:seattlecentral.edu/jwhorley/HEA125.html
• Password: IheartHEALTH!
– Powerpoint lectures
– Readings, Assignments & links to web resources
– Syllabus
– Learning Objectives
Office/phone:
Email:
Office Hours:
SAM 321; (206) 516-3125
[email protected]
M-Th
9:00 – 10:30
• Exams
– Two exams:; 31 Oct; 9 Dec
– DO NOT MISS THESE. NO MAKE-UP EXAMS
• Grading
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605 possible points
100 each exam (2)
10 each commentary (8)
50 for Autobiographical paper
100 each analytical paper (2)
25 each Diet Analysis (3)
• Cheating: PLEASE DON’T
• Extra Credit: Perhaps…in class
Course goals
• Understand the social determinants of health
• Learn a new language
• Learn to think critically and systematically,
like a natural scientist
• Have fun
• Learn to write analytically and critically
Biology background
• Characteristics of LIFE
• Levels of organization
– Cells - biosphere
• Tree of LIFE
– Who’s on it?
– How are they related?
– Which ones are common causes of disease?
• Scope
• Levels of
Organization
Interconnections: Matter
• ALL matter is recycled
• Producers
– Autotrophs; Algae,
Plants & Cyanobacteria
• Consumers
– Heterotrophs; Protists,
Animals & Bacteria
• Decomposers
– Saprotrophs; Fungi,
Bacteria
Interconnections: Energy
• Energy flows through
communities
– Producers harness it
(from the sun) & make
high energy molecules
– Consumers eat those
producers & use their
energy
– Decomposers absorb the
remainders & the
“undigestable” molecules
• Energy is lost as heat
along the way
All life is interconnected
• What atoms are you mostly made of?
• Where did those atoms come from?
• Is there turnover of these atoms as you
age?
Characteristics of Life
• Anything “alive” is composed of cells
– (1 - 100 billion)
• Autonomous, self-replication
– Pass on copies of genetic material (DNA/RNA)
• Make energy (ATP)
• Grow/develop
– Make Carbon-containing molecules (all organic
molecules have lots of Carbon; C)
Simple Prokaryotic cells
• Bacteria & Archaea
– Lack nuclei (have nucleoid region), no organelles
– Small
Anatomy of Eukaryotic cell
• Nucleus
• Smooth & Rough Endoplasmic
Reticulum
• Golgi Apparatus
• Lysosomes **
• Peroxisomes
• Plasma membrane
• Mitochondria
• Cytoskeleton
• Centrioles **
• Flagellum **
Anatomy of Plant cell
• Vacuole
– Full of carbohydrate
that we can digest
• Cloroplasts
– Have machinery that
makes food
• Cell wall
– Indigestible, but
necessary in our
diets
Diversity of life
• Bacteria & Archaea are
prokaryotes - no
nucleus; no complex
cellular machinery
(organelles)
• Eukarya are
eukaryotes - nucleus
plus lots of specialized
organelles
Evolutionary trees are like
family trees
Evolution background:
http://evolution.berkeley.edu/evosite/evo101/IIntro.shtml
Phylogeny of Eukarya
Which lineages are major
causes of disease
• Bacteria
– Tuberculosis (Mycobacterium sp.)
• Eukaryotic protozoans
– Malaria (Plasmodium sp.)
• Viruses
– Contemporary: HIV, Dengue, Influenza
– Historic: Smallpox, measles, polio, influenza
Relative sizes
• Many diseasecausing organisms
are very small.
Bacteria
Viruses
• These have sneaky ways of entering your
cells and silently (almost) fooling them into
making more viruses
Others: Worms!