Bio 100 – Guide 03 http://www.nevtron.si/borderline/dna.gif Monomers vs Polymers http://sps.k12.ar.us/massengale/glucose.gif http://www.langara.bc.ca/biology/mario/Assets/Amylopectin.jpg cturer.ukdw.ac.id/dhira/BacterialStructure/BactStructImages/aminoacids.GIF Primary Secondary Space Filling Model Tertiary http://consurf.tau.ac.il/2vaa1.gif Nucleic Acids are Polymers – DNA and RNA http://cyberlab.lh1.ku.ac.th/elearn/faculty/veterin/vet69/NUCLEIC_DREAMMX/PICTURE/PICTURE/P_05_3.gif Alfred Hershey and Martha Chase http://www2.carthage.edu/~pfaffle/hgp/ChaseHershey_1953.jpg 1953 http://oceanworld.tamu.edu/resources/oceanography-book/Images/BacteriophageCartoon.jpg http://www.mun.ca/biology/scarr/expt.gif Frederick Griffith's Experiment - 1928 Pneumococci in culture, has two forms: rough form (left), smooth form (right) Transformed! Avery–MacLeod–McCarty Experiment - 1944 Showed that DNA was the factor in Transformation – i.e. the genetic Erwin Chargaff. http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/B/BasePairing.gif http://www.amphilsoc.org/library/mole/c/chargaff.jpg http://www.fossilmuseum.net/images/WatsonCrick/watsonCrick.jpg http://bioweb.wku.edu/asp/bisc/images/WatsonCrick.jpg http://www.depts.ttu.edu/hs/hdfs3390/watson-crick.gif The famous photograph taken by Rosalind Franklin, showing the clear cross shape pattern of DNA by xray diffraction and which aided Watson and Crick to decipher the double helix structure of DNA. http://www.hmc.org.qa/hmc/heartviews/H-V-v4%20N1/F2.jpg http://www.kcl.ac.uk/depsta/ppro/dna/exhibitions.html DNA is Double Stranded DNA is a Double Stranded Helix Copying DNA is Called Replication http://ed.augie.edu/~bebecker/Termpaper/dna.gif http://www.chemsoc.org/ExemplarChem/entries/2003/imperial_Burgoine/basepair.jpg The Chemistry of DNA is Unique •Has a "melting temperature" •Long and thin - easily broken •Packing problem •Can use the base pairing to break and re-assemble pieces http://intermed.med.uottawa.ca/Pathology/devel/images/text_figure12.gif http://library.thinkquest.org/C0123260/basic%20knowledge/images/basic%20knowledge/RNA/genetic%20code.jpg http://www.wiley.com/legacy/college/boyer/0470003790/structure/tRNA/trna_diagram.gif http://fig.cox.miami.edu/~cmallery/150/cells/ribosome.jpg http://publications.nigms.nih.gov/insidethecell/images/ch2_ribosome_proteinbig.jpg http://fig.cox.miami.edu/~cmallery/150/gene/c7.17.16ribosome.jpg Shotgun Sequencing of DNA http://www.entu.cas.cz/fyziol/seminars/genome/shotgun.jpg http://www.bioinfo.org.cn/lectures/MappingProcedure.jpg http://www.scielo.cl/fbpe/img/bres/v35n3-4/34.jpg The End
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