Southern Africa Labour and Development Research Unit What do people actually learn from public health education campaigns? Incorrect inferences about male circumcision and female HIV infection risk in a cluster randomized trial in Malawi by Brendan Maughan-Brown, Susan Godlonton, Rebecca L. Thornton and Atheendar S Venkataramani Working Paper Series Number 104 About the Author(s) and Acknowledgments Brendan Maughan-Brown, Southern Africa Labour and Development Research Unit, University of Cape Town; Susan Godlonton, Ford School of Public Policy, University of Michigan; Rebecca L. Thornton, Department of Economics, University of Michigan; Atheendar S Venkataramani, Department of Medicine, Massachusetts General Hospital We would like to thank Martin Abel, Nicola Branson, Arden Finn, David Maughan-Brown, Rebecca Maughan-Brown and Elizabeth Gummerson for helpful comments and suggestions. Brendan MaughanBrown is grateful for funding from the National Research Foundation (NRF) Research Chair in Poverty and Inequality Research for his Postdoctoral Research Fellowship. Atheendar S. Venkataramani is grateful to the Massachusetts General Hospital Global Primary Care Program for travel and research support. Opinions expressed and conclusions arrived at, are those of the authors and are not necessarily to be attributed to the NRF. We acknowledge the extensive contributions of the field team including James Amani, Sheena Kayira, Collins Kwizombe, Denise Matthijsse, Ernest Mlenga, and Christopher Nyirenda. We also thank assistance from Kondwani Chidziwisano, Jessica Kraft, Erica Marks, Julie Moran, Jason Stanley, and Kondwani Tomoko. Sources of Funding: Funding for this study was provided by Michigan Center for Demography of Aging (MiCDA), OVPR and Rackham at the University of Michigan as well as the Institute for Research on Women and Gender. Godlonton and Thornton gratefully acknowledge use of the services and facilities of the Population Studies Center at the University of Michigan, funded by NICHD Center Grant R24 HD041028. The funders had no role in the collection, analysis, and interpretation of data, manuscript preparation, and in the decision to submit the article for publication. Recommended citation Maughan-Brown, B., Godlonton, S., Thornton, R., Venkataramani, A. (2013). What do people actually learn from public health education campaigns? Incorrect inferences about male circumcision and female HIV infection risk in a cluster randomized trial in Malawi. A Southern Africa Labour and Development Research Unit Working Paper Number 104. Cape Town: SALDRU, University of Cape Town ISBN: 978-1-920517-45-8 © Southern Africa Labour and Development Research Unit, UCT, 2013 Working Papers can be downloaded in Adobe Acrobat format from www.saldru.uct.ac.za. Printed copies of Working Papers are available for R15.00 each plus vat and postage charges. Orders may be directed to: The Administrative Officer, SALDRU, University of Cape Town, Private Bag, Rondebosch, 7701, Tel: (021) 650 5696, Fax: (021) 650 5697, Email: [email protected] What do people actually learn from public health education campaigns? Incorrect inferences about male circumcision and female HIV infection risk in a cluster randomized trial in Malawi Brendan Maughan-Brown, Susan Godlonton, Rebecca L. Thornton and Atheendar S Venkataramani SALDRU Working Paper Number 104 University of Cape Town August 2013 Abstract Objective: To examine whether individuals who learn that voluntary medical male circumcision (VMMC) partially reduces female-to-male HIV transmission erroneously infer a reduction in male-to-female HIV transmission risk. Design: Cluster randomised controlled trial. Methods: In 2008, information that VMMC reduces female-to-male HIV transmission risk was randomly disseminated to men in rural Malawi, with follow-up in 2009 (n=917). Data was collected on perceived male and female HIV-transmission risks. We assessed whether beliefs about male circumcision and female HIV-risk varied by receipt of VMMC information and by whether or not individuals believed that VMMC partially protects men from HIVinfection. Results: Men informed about VMMC were more likely to believe that sex with a circumcised male would confer lower transmission risk for women vis-à-vis sex with an uncircumcised male (38% versus 50%, p <0.01). Multivariate regression analyses showed that incorrect inferences were most likely to be made by those who believed that circumcised men were partially protected from contracting HIV. Consistent with this, instrumental variable analyses indicated that those individuals who received information about VMMC, and consequently believed it, were 82 percentage points more likely to believe that male circumcision also protects women (p<0.01). The inferred reduction in direct HIV infection risk for women due to male circumcision was approximately 50%. Conclusions: Our results suggest the need for VMMC campaigns to make explicit that male circumcision does not directly protect women from HIV-infection. It is also important to assess whether incorrect inferences lead to updated self-perceived HIV-risk and the adoption of riskier sexual behaviours. Keywords: Male circumcision, female HIV risk, risk compensation, Southern Africa, HIV/AIDS, prevention, information campaigns Introduction Randomised clinical trials (RCTs) have shown that medical male circumcision substantially reduces the risk of female-to-male HIV transmission risk [1-4], but have found no significant relationship with male-to-female HIV transmission risk [5]. In response to these findings, many countries are rolling out large-scale voluntary medical male circumcision (VMMC) campaigns in order to reduce heterosexual male infections [6]. In order to create demand for VMMC, these countries have started disseminating information that male circumcision offers men partial protection against HIV-infection [7] (see Figure A1, Appendix, for an example). Several concerns arise with such information campaigns. With respect to VMMC, men may respond to information regarding its protective benefits by updating their beliefs about their own HIV-risk and consequently adopt riskier sexual behaviours.8-10 While a recent literature using experimental methods has found no evidence of risk compensation after a medical circumcision, it is unclear whether these null results generalise to other settings [11-14]. Another important, but not was well studied, concern is that individuals will erroneously infer that a reduction in the risk of female-to-male transmission of HIV due to VMMC also implies a lower risk of male-to-female transmission. Qualitative work has shown that a significant number of women may hold these incorrect beliefs [15,16]. These small sample findings are supported by evidence from a South African opinion poll showing that approximately a fifth of men and women believed that VMMC reduced the risk of HIV transmission from men to women [17]. Such incorrect inferences may be detrimental to HIV prevention efforts if they lead to updated self-perceived HIV-risk that ultimately encourage adoption of riskier sexual behaviours. This paper uses data from Malawi to examine whether men infer a lower risk of male-to-female transmission of HIV as a result of VMMC when randomly provided information about the protective benefits that accrue to men. Exploring whether incorrect inferences arise is important not only in the context of VMMC based prevention efforts, but also to better understand how and what individuals learn from public health messages, and any consequent threats to their efficacy, more generally. Methods Data We used pre-existing data from a randomised trial of a behavioural intervention conducted among Malawian men between October 2008 and November 2009 [13]. The trial was originally conceived to examine whether information about the protective benefits of male circumcision changed safe sexual practices among uncircumcised and circumcised men. Face-to-face baseline surveys were fielded between October and November 2008 in the Zomba district, located in the southern region of the country. Follow-up interviews were conducted approximately one year after the intervention with approximately 78% of the initial sample. A two-stage sampling strategy was used to select respondents. First, 70 villages were randomly selected, stratified by the distance from the nearest mosque. A full household 2 enumeration was conducted within each of these villages. Second, men aged 25 to 40 were randomly selected from the census of 2,567 men in the sample villages, stratified by religious affiliation (Christian or Muslim) in order to balance the sample across baseline circumcision status (given the high correlation between religion and circumcision in Malawi). Up to 20 men of each religious faith were selected from each village. A total desired sample size of 1380 individuals split across treatment and control was computed to detect a standardized effect size of 0.25 on condom use with 90% confidence and 90% power. At baseline, half the villages (35) were randomly assigned (using a random number generator) to the information treatment [13]. After completing the baseline interview, interviewers discussed a standardised information sheet (Figure 1) that explained the three randomised controlled trials that were conducted in Uganda, South Africa, and Kenya. Information was provided on the medical reasons why male circumcision is partially protective for men. Information on male circumcision and female HIV-infection risk was not explicitly provided. The lack of explicit information about transmission risk to women mirrors the content of most VMMC information campaigns [7] (see Figure A1, Appendix, for an example). The University of Michigan Institutional Review Board and the National Health Sciences Research Committee in the Ministry of Health of Malawi granted ethical approval for the study. To measure perceived HIV risk, participants were asked at baseline: “If 100 circumcised men slept with an HIV positive women last night, how many of them would acquire HIV?” They were also asked a similar question with reference to uncircumcised men: “If 100 uncircumcised men slept with an HIV positive women last night, how many of them would acquire HIV?” These questions were repeated verbatim at follow-up. At that time, respondents were also asked two questions assessing the relationship between male circumcision and female risk of HIV infection. The first question was “If 100 women each sleep with a circumcised man who is HIV positive last night, how many of them do you think would get HIV?” The second was “If 100 women each sleep with an uncircumcised man who is HIV positive last night, how many of them do you think would get HIV?” For each survey wave, we created a binary variable (=1) denoting respondents who reported a lower risk for circumcised men compared to uncircumcised men. Similarly, we created a binary variable (=1) for individuals who believed that women who have unprotected sex with an HIV-positive circumcised man would be at lower risk than when the man is uncircumcised. In addition, we created a continuous variable defined as the difference in perceived risk (i.e. number out of 100) for women who have unprotected sex with an HIV-positive circumcised man compared to women who have unprotected sex with an HIV-positive uncircumcised man. This variable provides a measure of the degree to which respondents believed that male circumcision directly lowers a woman’s risk of HIV infection. Analysis We first analysed differences in baseline socioeconomic and demographic characteristics in the VMMC information treatment and controls groups to evaluate the success of randomisation. We then compared the measures of beliefs about the protective benefits of circumcision accruing to men and women across the two groups. This analysis recovers the average impact of randomised exposure to treatment regardless of whether 3 the respondents believed the messages or not (i.e. intent-to-treat estimate). We next assessed the proportion of men at follow-up that believed that VMMC partially protected men against HIV who also believed that VMMC lowered a woman’s risk of HIV infection. This analysis is salient given that the latter (correct) belief is the end goal of campaigns to create awareness and demand for VMMC. Additionally, to obtain an initial assessment of the degree to which these particular men believed that VMMC protects women, we computed the average of the difference in perceived HIV infection risk for women with a circumcised versus uncircumcised male partner. We then estimated three sets of multivariate models. In the first, we regressed our two dependent variables of interest against a dummy indicator (= 1) for assignment to the information treatment about VMMC, controlling for a number of baseline socioeconomic characteristics which we describe below. This set of models effectively serves as a multivariate generalisation of the means analysis described above and serves as a benchmark for subsequent analyses. In the second set of models, we added a binary indicator of whether the individual reported, in 2009, that circumcision is protective for men. The aim of these models were to assess the extent to which the effect of the information treatment was mitigated after controlling for beliefs about risk for men; that is, to assess whether incorrect inferences about risk for women driven by treatment worked through forming correct beliefs about risk for men. Our third set of models uses an instrumental variables (IV) strategy to examine the likelihood of forming incorrect beliefs as a result of internalising VMMC education messages, as well as the degree to which this erroneous belief was held. Specifically, we used the randomised treatment indicator as an instrument for believing that VMMC partially protected men from HIV, which serves as our primary explanatory of interest. This analysis provides the Local Average Treatment Effect (LATE) estimate of the effect of the information treatment on those who were actually affected by its message (i.e. treatment on treated estimate) [18]. For example, in models examining whether or not an individual believes that female HIV risk is lower with sex with a circumcised man, the coefficient on the main independent variable can be interpreted as the effect on the likelihood of inferring a protective benefit for women among those men who on the margin were induced, as a result of random assignment to information, to move from not believing that VMMC was protective for men to holding this belief. This LATE estimate is policy relevant for the same reason as stated above: VMMC campaigns seek to increase demand by shifting beliefs about circumcision’s HIV risk protective benefits. The validity of the IV approach relies on (1) the instrument being correlated with the explanatory variable of interest but (2) not with any other factor that may influence the outcome. As in Godlonton et al. (2012), we show below that random assignment to treatment is strongly correlated with beliefs about the protective benefits of VMMC for men.13 As for the second condition, we argue that the information treatment is likely uncorrelated with any other determinants of the dependent variable; it is difficult to imagine how a simple, discrete message about VMMC and male HIV risk could affect beliefs about risks to women other than through the internalisation about beliefs about male risks. For our multivariate analyses, the following control variables from the baseline (2008) survey were included in each of the models: circumcision status, age, years of education, literacy in Chichewa (the most commonly spoken local language), number of 4 household assets, logged monthly household income (with incomes or zero replaced with 1 Kwacha (n=13)), the number of HIV-related radio messages heard the past 30 days, and an indicator of whether the respondent believed that HIV is transmitted via mosquitoes or kissing. Also of note, Ordinary Least Squares (OLS) regression models were also used for all models with binary dependent variables, for ease of interpretation. Using OLS for binary dependent variables is a valid statistical method [19]. Results are robust to logit, probit or odds ratio models. All standard errors were corrected for heteroskedasticity and for clustering at the village level (the unit of randomisation). Results The baseline (2008) sample consisted of 1,228 male respondents (treatment group: n=609; control group: n=619). Approximately 78% (n=953; treatment group: n=484(79%); control group: n=468(76%)) were re-interviewed in 2009. Reasons for loss to follow-up included participants moving to other regions, being unreachable at the address or telephone number provided and refusal participate. Previous analysis found that attrition in this sample was not significantly associated with treatment status, circumcision status, age, education, marital status, or perceptions about male circumcision and HIV risk [13]. The sample used in the current analysis consisted of 917 men who were interviewed in both waves and for whom we had complete data for all relevant dependent and independent variables. Complete data was not available for 18 men in the treatment group and 18 men in the control group. Table 1 presents summary statistics of baseline (2008) characteristics and beliefs about male circumcision and HIV risk (2008 & 2009) by treatment (n=466) and control groups (n=451). The results indicate that the treatment and control groups had substantively similar demographic characteristics, access to information, and knowledge about HIV (see Table A1, Appendix, which demonstrates statistical equivalence across an additional set of baseline demographic characteristics). Overall, the sample comprised relatively poor, married men with low levels of education (the average respondent had completed only 1 year of high school). The majority were farmers whose access to the media consisted of listening to the radio. Understanding about HIV transmission was poor: almost two thirds of individuals in the treatment and control groups reported the belief that HIV can be transmitted by mosquitoes or through kissing. Consistent with the broader literature [22-22], respondents vastly overestimated the probability of HIV transmission. At baseline, participants in the treatment and control group believed, on average, that around 90 out of 100 (90%) uncircumcised men would get HIV if they had unprotected sex with an HIV positive woman and that around 81% of circumcised men would get HIV if they had unprotected sex with an HIV positive woman. On average, participants in 2008 believed that circumcised men experienced a 10 percentage point reduction (p<0.001) in the chance of contracting HIV after a single encounter with an infected partner vis-à-vis uncircumcised men. At follow-up, the average participant reported a significantly lower perceived risk for circumcised men compared to their baseline beliefs in both the treatment (-17 percentage points, p<0.01) and control group (-11 percentage points, p<0.01). Overall, the majority of individuals in the treatment group (56%) and a significant proportion of the control group (45%) reported a decrease in perceived HIV risk 5 for circumcised men between surveys (results not shown). With regard to perceived female HIV risk at follow-up in 2009, participants reported that on average around 90 out of a hundred women would get HIV if they had unprotected sex with an uncircumcised man living with HIV. Significant proportions of men in the treatment (50%) and control group (38%) reported the belief that the HIV risk for women is lower when her sexual partner is a circumcised man compared to an uncircumcised man. Perceived female HIV risk in the scenario involving a circumcised man was, on average, 17 percentage points lower (p<0.01) in the treatment group and 11 percentage points lower (p<0.01) in the control group. The difference across treatment and control in the differential perceived risk to women across uncircumcised and circumcised individuals was 6% (p<0.01). The lower panel in Table 1 presents perceived HIV risk for women with respect to VMMC among those that believed (in 2009) that male circumcision partially protects men against HIV infection. The vast majority of participants in both the treatment (73%) and control group (70%) who believed that VMMC protects men also believed that VMMC protects women. The average participant in the treatment group who believed that VMMC protects men reported the belief that VMMC protects women by 26 percentage points. Put differently, they believed that male circumcision led to roughly a 30% reduction in the female risk of contracting HIV (26 percentage points divided by the sample risk of contracting HIV with an uncircumcised partner). Table 2 presents the results from the multivariate regression models. The results in the first column show that random assignment to the information treatment was associated with a 10 percentage point increase in the likelihood of believing that male circumcision lowers a woman’s risk of HIV infection. In the second column, men randomised to VMMC information believed that women were over 5 percentage points less likely to contact HIV after sleeping with a seropositive circumcised versus uncircumcised man. Both of these estimates are similar to those from the simple comparison of means across the treatment and control group, which adds confidence that assignment to treatment was orthogonal to measured and unmeasured confounders. Columns 3 and 4 present results for the second set of models. In both cases, including a binary indicator for believing that circumcision protected men from contracting HIV from a seropositive woman led to large absolute declines in the treatment group coefficient. Those men who believed in the protective benefits of circumcision for men were 64 percentage points more likely (p<0.01) to also believe that male circumcision lowers a woman’s risk of HIV infection. In addition, the belief that circumcised men were protected from HIV was associated with a 21 percentage point greater risk reduction (p<0.01) in the probability of HIV transmission from men to women than men who did not believe that VMMC protects men. The last two columns present the IV results. The results in column 5 indicate that men who were informed about VMCC and believed that male circumcision partially protects men from HIV infection were 82 percentage point more likely than their counterparts to believe that male circumcision lowers a woman’s risk of HIV infection (p<0.01). Column 6 shows that the same men inferred that male circumcision protects women by 45 percentage points (p<0.01), or that male circumcision reduced the per act risk of female HIV transmission by over 50%. Notably, the first stage Wald F-statistic for these IV regressions was 15.73, implying that weak instrument bias is not an issue for the coefficient estimates [23]. 6 Discussion Large-scale public health programs often involve education and information dissemination efforts in order to affect behaviour change or generate demand for health products. Their success depends on how individuals internalise the messages and thereafter act on them. However, it is also possible that individuals infer aspects from these messages that are not correct, which could undermine the efficacy of such campaigns. In this study, we examined what individuals learn from information campaigns highlighting the protective benefits of male circumcision in reducing HIV risk among men. Previous research in rural Malawi has shown that men correctly internalise the protective benefits of VMMC in response to a randomly assigned information campaign built around this message [13]. This study builds on this work and demonstrates that the same men also incorrectly infer that male circumcision protects women from contracting HIV, despite the lack of any explicit statement about female risk in the information campaign. Furthermore, the perceived degree to which VMMC reduces a woman’s risk of HIV infection was large, in the order of 50%. Recent qualitative studies [15,16] and an opinion and beliefs poll [17] have suggested that many individuals believe that male circumcision directly reduces a woman’s risk of HIV infection, but until now evidence from observational studies or randomised controlled trials has been lacking. Our study presents the first evidence from a randomised controlled trial on incorrect inferences made from information about VMMC. However, our study also has some important limitations. First, we do not know what other circumcisionrelated messages participants received during the study period. It is possible that media campaigns directly stated that VMMC protects women. However, unless outside messages were delivered differentially across the treatment groups, the internal validity of our analysis is not threatened. Second, our data come from a sample of rural men and our findings may not be applicable in other populations. However, one sign that mistaken inferences may be generalisable is that we found no differences in the likelihood of making incorrect inferences about HIV risk across differences in education, wealth, and access to media (available upon request), which is similar to recent findings in South African data [17]. Importantly, there were also no differences in the proportion of men and women holding incorrect beliefs in the South African data [17], which indicates that women are making similar incorrect inferences. Our results have a number of implications for public health policy. Mainly, the findings demonstrate that individuals may actively project the messages of information campaigns to groups that do not actually benefit from a particular intervention or change in behaviour. In our study the proportion of individuals making incorrect inferences was substantively large. Given that the majority of public health prevention-messages for diseases which affect both men and women apply to both groups, incorrect inferences may be especially common in cases where a disease affects both men and women but a public health message only applies to one gender. Thus, VMMC information campaigns, now being rolled out across sub-Saharan Africa, and prevention campaigns more generally should be clear about who benefits from the specific interventions they promote, and who does not. Along these lines, we believe that future research should focus on two areas. The first is to assess whether incorrect inferences are made in other public health settings. The second is to better understand when and how incorrect inferences about VMMC and female 7 HIV risk are formed, especially among women, and the behavioural consequences of such inferences. Risk compensations stemming from incorrect inferences that VMMC offers women some protection against HIV could reduce the efficacy of VMMC campaigns and other HIV prevention efforts. This causal pathway could explain recent results showing risk compensatory behaviours among women informed about the protective benefits of circumcision [24,25], particularly in the context of population level data showing that a significant minority of both men and women believed that VMMC directly protects women in at least one setting [17]. Large-scale information campaigns will continue to be a mainstay of prevention efforts. Indeed, VMMC programs in sub-Saharan Africa are using such campaigns to increase demand for male circumcision services. Specific to these campaigns, our evidence strongly suggest that educational messages should explicitly state that at present there has been no significant relationship found between VMMC and direct protection for women. In addition, we recommend further research into what individuals learn and infer from public health education messages more generally, and how these messages can be better tailored to prevent incorrect inferences and potentially thereby enhance their efficacy. References 1 Auvert B, Taljaard D, Lagarde E, Sobngwi-Tambekou J, Sitta R, Puren A. Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 Trial. PLoS Med 2005; 2:1112–22. 2 Gray RH, Kigozi G, Serwadda D, Makumbi F, Watya S, Nalugoda F, et al. Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial. Lancet 2007; 369:657–66. 3 Bailey R, Moses S, Parker C, Agot K, Maclean I, Krieger J, et al. 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Scoping Report on Interventions for Increasing the Demand for Voluntary Medical Male Circumcision. 2013. http://www.3ieimpact.org/media/filer/2013/03/22/white_paper__vmmc.pdf 8 Cassell M, Halperin D, Shelton J, Stanton D. Risk compensation: the Achilles' heel of innovations in HIV prevention? BMJ 2006; 332:605–7. 9 Kalichman S, Eaton L, Pinkerton S. Circumcision for HIV prevention: failure to fully account for behavioral risk compensation. PLoS Med 2007; 4:e138–46. 10 Namangale F. Approach Male Circumcision with Caution. Malawi Daily Times. 2007, March 9. 11 Agot K, Kiarie J, Nguyen H, Odhiambo J, Onyango TM, Weiss NS. Male Circumcision in Siaya and Bondo Districts, Kenya. Prospective Cohort Study to Assess Behavioral Disinhibition Following Circumcision. J Acquir Immune Defic Syndr 2007; 44:66–70. 12 Mattson CL, Campbell RT, Bailey RC, Agot K, Ndinya-Achola J, Moses S. 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Global Journal of Community Psychology Practice 2011; 1:1–11. 17 Maughan-Brown B, Venkataramani A. Incorrect Beliefs About Male Circumcision and Male-to-Female HIV Transmission Risk in South Africa: Implications for Prevention. J Acquir Immune Defic Syndr 2013; 62(4):e121-123. 18 Angrist JD, Imbens GW, Rubin DB. Identification of Causal Effects Using Instrumental Variables. J Am Stat Assoc 1996; 91:444–55. 19 Angrist JD, Pischke J-S. Mostly Harmless Econometrics. Princeton: Princeton University 9 Press, 2008. 20 Anglewicz P, Kohler H-P. Overestimating HIV infection: The construction and accuracy of subjective probabilities of HIV infection in rural Malawi. Demogr Res 2009; 20:65–96. 21 Kerwin J, Thornton R, Foley S. Prevalence of and Factors Associated with Oral Sex among Rural and Urban Malawian Men. Working Paper, University of Michigan 2012. http://paa2012.princeton.edu/papers/122619 22 Sterck O. Should Prevention Campaigns Disclose the Transmission Rate of HIV/AIDS? Theory and Application to Burundi. Social Science Research Network (SSRN) 2012; 2097868. doi:10.2139/ssrn.2097868 23 Bound J, Jaeger DA, Baker RM. Problems with Instrumental Variables Estimation When the Correlation Between the Instruments and the Endogeneous Explanatory Variable is Weak. J Am Stat Assoc 1995; 90:443–50. 24 Maughan-Brown B, Venkataramani A. Learning That Circumcision Is Protective against HIV: Risk Compensation among Men and Women in Cape Town, South Africa. PLoS ONE 2012; 7:1–9. 25 Okeyo T, Westercamp N, Bailey RC, Agot K, Jaoko W. What women think about male circumcision: perceptions of the female partners of recently circumcised men in Nyanza Province, Kenya [TUAC0401]. Paper presented at: XIX International AIDS Conference; July 24, 2012; Washington DC. 10 Figure 1: Standardized information sheet received by participants in the treatment group 11 Table 1: Descriptive Statistics and Differences in Outcomes by Treatment and Control Group Treatment (n=466) Mean (SD) or % 31.5 (0.31) 5.7 (0.16) *14730 (877) 4.2 (0.1) 64% 74% Control (n=451) Mean (SD) or % 31.9 (0.32) 6.1 (0.17) 15236 (789) 4.6 (0.1) 63% 72% Diff. P-val. 0.4 0.4 506 0.4 0.5% 2% 0.36 0.08 0.66 0.002 0.86 0.33 Household owns a TV Listen to radio daily HIV transmitted by mosquitoes or through kissing 3.20% 53% 65% 3.50% 53% 62% 0.30 % 0.4% 4% 0.78 0.9 0.23 Perceived male HIV risk Baseline (2008) † Number (0-100) of uncircumcised men infected with HIV (2008) † Number (0-100) of circumcised men infected with HIV (2008) Believed male HIV risk is lower for circumcised men (2008) Follow-up (2009) † Number (0-100) of uncircumcised men infected with HIV (2009) 92 (19) 81 (30) 32% 90 (21) 82 (29) 31% 2 1 1% 0.22 0.64 0.78 88 (21) 89 (20) 1 63 (34) 71 (33) 8 65% 50% 14% 0.31 <0.00 1 <0.00 1 Perceived female HIV risk (2009) † Number of women (0-100) infected with HIV, partner uncircumcised † Number of women (0-100) infected with HIV, partner circumcised 90 (20) 89 (20) 1 0.65 72 (32) 78 (30) 6 Believed female HIV risk is lower with a circumcised man Female risk differential with circumcised vs uncircumcised man 50% -17 (25) 38% -11 (22) 12% 6 <0.01 <0.00 1 <0.01 Treatment (n=301) Mean (SD) or % 73% Control (n=227) Mean (SD) or % 70% Diff. P-val. 4% 0.33 -26 (26) -21 (26) 5 0.04 Estimation sample Age Years of education Monthly household income (Kwacha) Household asset index (0-13) Farmer Circumcised † Number (0-100) of circumcised men infected with HIV (2009) Believed male HIV risk is lower for circumcised men (2009) Sample who believed that male HIV risk is lower for circumcised men (2009) Believed female HIV risk is lower with a circumcised man Female risk differential with circumcised vs uncircumcised man Notes: P-value derived from two-sample differences in means or proportion test across groups. *The Malawian Kwacha to US Dollar exchange was 0.007036 on October 31, 2008, so K14730 was equivalent to $104. † All HIV risk variables based on unprotected sex with an HIV-positive person of the opposite sex. See main text for details. The difference column does not always equate to difference between the figures displayed for the treatment and control group because all figures have been rounded to the nearest integer. 12 Table 2: Multivariate Ordinary Least Squares (OLS) and Instrumental Variable (IV) models for beliefs about male circumcision and a woman’s risk of HIV infection. Model: Dependent variable: Treatment group (=1) Believed male HIV risk is lower for circumcised men (2009) (1) OLS (2) OLS Believed risk is lower Risk differential 0.102** -5.592*** (0.042) (1.815) Believed male HIV risk is lower for circumcised men (2008) Circumcised (2008) Age Years of education (2008) Literate in Chichewa (2008) Household assets (2008) Logged monthly household income (2008) Number of HIV messages heard on radio (2008) Believed HIV transmitted via mosquito or kissing (2008) 0.149*** (0.032) -0.005** (0.002) -0.005 (0.006) 0.016 (0.051) -0.0151* (0.008) 0.010 (0.012) -0.001 (0.001) -0.012 (0.031) -6.818*** (1.507) 0.092 (0.120) 0.132 (0.283) -0.136 (2.507) 0.556 (0.374) -0.044 (0.606) 0.070 (0.052) 0.093 (1.645) (3) OLS Believed risk is lower 0.022 (0.032) 0.638*** (0.028) 0.018 (0.033) 0.012 (0.021) -0.001 (0.002) 0.002 (0.005) -0.027 (0.039) -0.010 (0.006) 0.005 (0.007) -0.001 (0.001) 0.001 (0.023) (4) OLS Risk differential -2.955** (1.437) -21.14*** (1.523) -1.573 (1.908) -2.154 (1.414) -0.043 (0.100) -0.114 (0.251) 1.338 (2.188) 0.380 (0.304) 0.130 (0.489) 0.0796* (0.046) -0.375 (1.469) (5) IV Believed risk is lower (6) IV Risk differential 0.817*** (0.249) -0.023 (0.066) -0.021 (0.045) 0.000 (0.002) 0.004 (0.006) -0.036 (0.044) -0.008 (0.007) 0.003 (0.008) -0.001 (0.001) 0.002 (0.023) -45.07*** (11.540) 3.905 (3.540) 2.222 (2.470) -0.172 (0.122) -0.350 (0.295) 2.545 (2.337) 0.177 (0.362) 0.361 (0.532) 0.082 (0.053) -0.486 (1.696) Robust standard errors, clustered at the respondent village level (69 clusters) in parentheses. *** - p<0.01, ** - p<0.05, * - p<0.01 Dependent variables: (1) “Believed risk is lower” is the proportion of men that believed that a woman’s risk of HIV infection is lower with a circumcised man. (2) “Risk differential” is the difference in perceived HIV transmission risk from males to females between circumcised and uncircumcised sexual partners. Treatment group = 1 if the respondent was randomly assigned to receive VMMC prevention information. The rest of the variables are defined in the main text. 13 Appendix Figure A1: Poster distributed in Zambia to increase awareness about Male Circumcision and HIV prevention (Downloaded from “Clearinghouse on Male Circumcision for HIV Prevention” website: http://www.malecircumcision.org/programs/mass_media_materials.htm, 15 April 2013) 14 Table A1: Additional baseline characteristics by randomisation to treatment Married Christian Muslim Tribe: Nyanja Yao Lomwe Chewa Literacy in Chichewa Literacy in English treatment (n=466) control (n=451) % % 91 88 56 52 37 40 42 32 21 4 77 34 42 37 13 6 77 39 difference % 3 4 2 p-value 0 5 7 1 0 5 0.98 0.11 <0.01 0.38 0.96 0.14 0.18 0.24 0.46 15 southern africa labour and development research unit The Southern Africa Labour and Development Research Unit (SALDRU) conducts research directed at improving the well-being of South Africa’s poor. It was established in 1975. Over the next two decades the unit’s research played a central role in documenting the human costs of apartheid. Key projects from this period included the Farm Labour Conference (1976), the Economics of Health Care Conference (1978), and the Second Carnegie Enquiry into Poverty and Development in South Africa (1983-86). At the urging of the African National Congress, from 1992-1994 SALDRU and the World Bank coordinated the Project for Statistics on Living Standards and Development (PSLSD). This project provide baseline data for the implementation of post-apartheid socio-economic policies through South Africa’s first non-racial national sample survey. In the post-apartheid period, SALDRU has continued to gather data and conduct research directed at informing and assessing anti-poverty policy. In line with its historical contribution, SALDRU’s researchers continue to conduct research detailing changing patterns of well-being in South Africa and assessing the impact of government policy on the poor. Current research work falls into the following research themes: post-apartheid poverty; employment and migration dynamics; family support structures in an era of rapid social change; public works and public infrastructure programmes, financial strategies of the poor; common property resources and the poor. Key survey projects include the Langeberg Integrated Family Survey (1999), the Khayelitsha/Mitchell’s Plain Survey (2000), the ongoing Cape Area Panel Study (2001-) and the Financial Diaries Project. www.saldru.uct.ac.za Level 3, School of Economics Building, Middle Campus, University of Cape Town Private Bag, Rondebosch 7701, Cape Town, South Africa Tel: +27 (0)21 650 5696 Fax: +27 (0) 21 650 5797 Web: www.saldru.uct.ac.za
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