B1 Learning Outcome Questions 1. 2. 3. Question Why blood in arteries is under pressure: Describe how cholesterol can restrict the flow of blood to the heart. What do blood pressure measurements consist of? 4. Describe 4 factors that factors that increase blood pressure 5. Describe two factors that decrease blood pressure: 6. Give the possible consequences of having high blood pressure 7. Give the possible consequences of having low blood pressure 8. Explain the difference between fitness (the ability to do physical activity) and health (free from disease). 9. List the different ways in which you could measure a person’s fitness 10. Explain how smoking increases blood pressure: 11. Explain how carbon dioxide reduces the ability of red blood cells to carry oxygen 12. Explain how diet can increase the risk of heart disease. 13. Describe the possible causes of a heart attack 14. Explain what a balanced diet should include and why. 15. Describe how carbohydrates, fats or proteins are stored in the body in the body 16. Explain why a high protein diet is necessary for teenagers Answer • due to contraction of heart muscles • so that it reaches all parts of the body. Cholesterol can restrict or block blood flow in arteries by forming plaques diastolic and systolic data in mmHg. • being overweight • stress • high alcohol intake • smoking. • regular exercise • balanced diet. stroke kidney failure poor circulation dizziness fainting fitness - the ability to do physical activity health - free from disease. strength flexibility stamina agility speed • carbon monoxide reduces the oxygen-carrying capacity of the blood so heart rate increases to compensate • nicotine increases heart rate. Carbon monoxide combines permanently with the haemoglobin in red blood cells, preventing them from carrying oxygen • saturated fats leading to a build up of cholesterol (a plaque) in arteries • high levels of salt elevating blood pressure. Build up of cholesterol or a thrombosis (blood clot) in the main blood vessels to the heart preventing blood flowing to the heart • protein – for growth and repair • carbohydrates and fats – for energy and to keep warm • minerals (limited to iron) – to produce haemoglobin for the red blood cells and prevent anaemia • vitamins (limited to vitamin C) – to stay healthy and prevent scurvy • fibre – to prevent constipation • water.- to prevent dehydration and constipation Carbohydrates in liver as glycogen or converted to fats Fats stored under the skin and around organs a adipose tissue Proteins aren’t stored Teenagers need enough protein to grow 17. Explain in many parts of the world diets are deficient in protein. Protein deficiency (kwashiorkor) is common in developing countries, due to • overpopulation • limited investment in agricultural techniques. 18. When are proteins used as an energy source? Only when fats or carbohydrates are unavailable. 19. State 4 health risks that are linked to being very overweight (obese)? 20. What are carbohydrates, fats and proteins made up of? arthritis, heart disease, diabetes and breast cancer. • carbohydrates are made up of simple sugars such as glucose • fats are made up of fatty acids and glycerol • proteins are made up of amino acids. 21. What is the difference between first and second class proteins? 22. Why might different people eat different balanced diets? 23. What factors increase a persons estimated average daily requirement (EAR) for protein 24. Explain why people in the UK with access to enough healthy food might still have a poor diet. 25. What are infectious diseases are caused by? First class proteins are from animals and contain all the essential amino acids, whereas second class proteins come form plants a balanced diet will vary depending on age, gender, activity, religion, personal choice (to include vegetarians and vegans) and medical issues (including food allergies). More active life style Age – people still growing need more protein Pregnancy and breast feeding Low self-esteem, poor self-image and desire for perfection can lead to a poor diet pathogens (disease-causing microorganisms). 26. Explain how pathogens cause the symptoms of an infectious disease. by cell damage or by production of toxins. 27. What are the four types of pathogens? Give an example of a disease caused by each type. Fungi -athlete’s foot Viruses – flu Bacteria – cholera Protozoa - Malaria • skin provides a barrier • blood clotting prevents entry of pathogens • pathogens are trapped by mucus in airways • hydrochloric acid in the stomach kills pathogens. 28. Describe 4 ways that the human body is defended against pathogens. 29. Describe the difference between infectious and noninfectious diseases. Infectious – can be transmitted from people or animals Non-infectious – cannot be transmitted 30. Describe the difference between benign and malignant tumours Benign tumours are harmless and slow to divide, whereas malignant tumours are cancerous and spread throughout the body Gives protection from certain pathogens. 31. What do immunisations (vaccinations) do? 32. Explain the process of immunisation (vaccination) 33. Describe the advantages and disadvantages of immunisation 34. Explain the difference between passive and active immunity 35. How are pathogens that enter the body destroyed by the immune system? 36. Why does each pathogen require the body to produce a different set of antibodies to destroy it? 37. Recall the meaning of the terms parasite, host and vector with reference to malaria. 38. How can we use our knowledge of how the disease is passed on to prevent the spread of malaria? 39. State the difference between antibiotics and antiviral drugs. 40. Why must doctors limit their use of antibiotics? 41. Describe how animals detect changes in their environment (stimuli) using receptors which generate nerve impulses. 42. Label the main parts of the eye and state their Harmless pathogen given which carries antigens Antigens trigger immune response by white blood cells which produce antibodies Immunity remains as memory cells produced that can produce antibodies if pathogen returns Once the majority of a population is immunised it prevents the disease from spreading, although some vaccinations do have harmful side effects Passive immunity – receive antibodies active immunity - make own antibodies engulfed by white blood cells • antibodies lock on to antigens leading to the death of the pathogens. Each pathogen has it’s own antigens Parasite – an organism that depends on another organism to survive (the protozoa) Host – an organism that provides a parasite with food and is harmed by it (the human) Vector – an organism that spreads disease without being affected by the disease (the mosquito) Avoiding stagnant water where mosquito larvae grow Using mosquito nets to prevent adult mosquitoes feeding on humans and passing on parasite Using insecticide to kill adult mosquitoes Antibiotics – fight bacteria Antiviral – fight viruses To prevent the increase of pathogens resistant to antibiotics, such as MRSA touch, taste, sight, sound, smell all make nerve impulses that are carried by the nervous system. Use your revision book or exercise book to check you can function. 46. Explain how binocular vision helps to judge distances label an eye. • cornea - refracts light • iris - controls how much light enters pupil • lens - focuses light on to retina • retina - contains light receptors, some sensitive to light of different colours • optic nerve - carries impulses to the brain. The light is refracted by the cornea and lens and brought to focus on the retina. Ciliary muscles and suspensory ligaments in the sys act to make the lens fatter (to refract light more) or thinner • monocular vision: wider field of view but poorer judgement of distance • binocular vision: narrower field of view but better judgement of distance. by comparing the images from each eye - the more similar the images, the further away the object. 47. Describe three main problems in vision. Long-sight, short-sight and red-green colour blindness. 48. Why are some people long and short-sighted? Because the eyeball or the lens is the wrong shape. 49. Why are some people red-green colour blind? They have a lack of specialised cells in the retina. 50. How can long and short-sightedness be corrected? Corneal surgery Glasses or contact lenses (Short sightedness needs concave (curving in) lenses; whereas long sightedness needs convex (bulging out) • the central nervous system (CNS) (brain and spinal cord) • the peripheral nervous system. 43. Describe the pathway of light through the eyeball. 44. Explain how the eyes focuses light (accommodation) from near and distant objects 45. Explain the advantages and disadvantages of monocular and binocular vision. 51. Name the two main parts of the nervous system. 52. How are message carried by nerves? The nerve impulse is an electrical signal that is carried by nerve cells called neurones. 53. Name and locate the parts of a motor neurone: Labels: Cell body, axon and sheath. Use your revision guide or exercise book to check the diagram The nerve impulse passes along the axon of a neurone. 54. Explain how neurones are adapted for their function Long Insulated sheath (stops impulses crossing over) Branched endings (allows impulses to be picked up) Reflex actions - fast, automatic and protective responses (eg pulling your hand away from a hot plate) Voluntary responses – controlled by the brain 55. What are the difference between reflex actions and voluntary responses? 56. Describe a reflex arc Stimulus - receptor - sensory neurone – central nervous system - motor neurone - effector - response 57. What is the gap between neurones called? 58. How does an impulse pass across a synapse? Synapse A transmitter substance is released which diffuses across to bind with receptor molecules in the membrane of the next neurone, causing the impulse to continue Addiction = relied on by the body so it is hard to give up Withdrawal symptoms = side effects, such as bad temper, of giving up a drug Tolerance = over time people need bigger doses of the drug to get an effect Rehabilitation = Process of a person overcoming an addiction depressants: slow down brain’s activity • pain killers: block nerve impulses • stimulants: increase brain’s activity • performance enhancers: muscle development • hallucinogens: distort what is seen and heard. • Class A is the most dangerous with the heaviest penalties • Class C is the least dangerous with the lightest penalties. 59. Explain the terms: addiction, withdrawal symptoms, tolerance and rehabilitation. 60. Describe the general effects of each drug category. 61. Explain the basis of the legal classification of drugs: 62. State examples of each type of drug. • depressants - alcohol, solvents and temazepam • pain killers- aspirin and paracetamol • stimulants - nicotine, ecstasy and caffeine • performance enhancers – anabolic steroids • hallucinogens - LSD. 63. Explain the action of depressants and stimulants on the synapses of the nervous system Depressants bind with receptor molecules in the membrane of the next neurone blocking the transmission of the impulses Stimulants cause more neurotransmitters to cross the synapse 64. What health problems can tobacco smoking cause? 65. Describe the effects of the 4 components of cigarette smoke. 66.Explain why damage to ciliated epithelial cells can lead to a ‘smokers cough’. 66. Describe the short term and long term effects of alcohol on the body. 67. Describe how the liver can become damaged as it removes alcohol (cirrhosis) 68. What does the body need to maintain steady levels of? What is this called? 69. What is negative feedback? 70. What is normal body temperature? Why is it important for the body to be kept at this temperature? 71. Which part of the brain controls balance of conditions within the body? 72. Describe where on the body to measure body temperature, and what instruments can be used. emphysema, bronchitis, cancer (mouth, throat, oesophagus and lung) heart disease. • carbon monoxide (lack of oxygen, heart disease) • nicotine (addictive) • tars (irritant, carcinogenic) • particulates (accumulation in lung tissue). Ciliated epithelial cells (cilia) line the trachea, bronchi and bronchioles and become clogged up by tar and particulates. This stops the cilia moving the mucus and causes smokers cough. • short term effects- impaired judgment, balance and muscle control, blurred vision, slurred speech, drowsiness and increased blood flow to the skin. • long term effects - liver and brain damage When enzymes in the liver breakdown alcohol it produces toxic products that cause liver damage The body works to maintain steady levels of temperature, water, and carbon dioxide. This is called homeostasis. Altering the operation of the body in response to a change in a way that limits that change, i.e., if body detects an increase in temperature it tries to cool itself down 37°C - the optimum temperature for the action of many enzymes. Hypothalamus • where - ear, finger, mouth, or anus • how - using a clinical thermometer, sensitive strips, digital recording probes, or thermal imaging). 73. Describe how heat can be gained or retained by the body by respiration, shivering, exercise, less sweating, less blood flow near skin surface, or clothing 74. Describe how more heat can be lost by the body by sweating, or more blood flow near skin 75. Explain how sweating helps you to cool down. 76. Explain how vasodilatation and vasoconstriction increase or reduce heat transfer to the environment 77. Why is it dangerous for a person to get too hot or too cold? 78. Name and locate the pancreas. 79. Where is the hormone insulin produced? 80. What is the function of insulin? 81. How does insulin help regulate blood sugar levels? 82. What causes Type 1 diabetes? 83. How are Type 1 and Type 2 diabetes treated differently? 84. Why does the does of insulin required by a Type 1 diabetic alter? 85. Describe how insulin travels around the body 86. Explain why responses controlled by hormones are usually slower than responses controlled by the nervous system. 87. What is the name of the chemicals that control plant growth? (for example: growth of shoots and roots, flowering and fruit ripening) 88. What are auxins? 89. Where is auxin made? 90. How does auxin cause a plant to grow towards a light source? 91. State 5 uses of plant hormones. 92. Explain how growth towards light increases the plant’s chance of survival. sweating increases heat transfer to the environment by evaporation of sweat which requires heat, so removing heat from the skin. Vasodilatation (lowers temperature) – Blood capillaries dilate (widen)so blood nearer to the surface Vasoconstriction (raises temperature) – Blood capillaries constrict (narrow)so blood further from the surface High temperatures can cause heat stroke and dehydration and if untreated, death. Very low temperatures can cause hypothermia and if untreated, death. Use your revision guide or exercise book to check the diagram The pancreas controls blood sugar levels. When blood sugar levels are too high insulin converts some glucose in the blood into glycogen, which is stored in the liver. When blood sugar levels are too low it causes glycogen to be turned back into glucose the failure of the pancreas to produce insulin Type 2 diabetes can often be controlled by diet but Type 1 diabetes also needs to be treated by insulin dosage. Dose required to maintain insulin at normal levels depends on the diet and activity of the person In the blood Hormones travel in the blood much more slowly than electrical impulses travel along the nervous system. Plant hormones Auxins are plant hormones that: • move through the plant in solution • are involved in the response to light (phototropism) • are involved in the response to gravity (geotropism) In the tip of the shoot. If the tip is removed it stops growth Auxin collects on the shady side of the plant and causes cells on this side of the plant to elongate (stretch). Therefore the plant bends towards the light •speed up or slow down plant growth selective weedkillers • rooting powder • fruit ripening (delay or acceleration) • control of dormancy. More sunlight = more photosynthesis 93. Explain why roots grow downwards. 94. Explain the meaning of phototropic and geotropic 95. Describe the geotropism and phototropism of shoots and roots. To reach water and to provide support Phototropic – grows towards the light Geotropic – grows towards the ground Shoots - positively phototropic but negatively geotropic. Roots - negatively phototropic but positively geotropic. 96. Name 3 human characteristics that are a result of both environmental and inherited factors. • intelligence • body mass • height. 97. Where are your genes? Chromosomes are held in the nucleus and they carry information in the form of genes, which control inherited characteristics. 23 pairs 98. How many chromosomes do most human body cells have? 99. What is a gamete? 100. How many chromosomes do gametes have? A sperm or egg cell. Half the number of normal cells or 23 101. Identify inherited characteristics as dominant or recessive when given the results of a breeding experiment. Dominant characteristics – always show (eg brown eyes) Recessive characteristics – the gene can be present but not show (eg blue eyes) 102. What are alleles? 103. Explain how dominant and recessive characteristics depend on dominant and recessive alleles 104. What do the following words – homozygous, heterozygous, genotype and phenotype – mean? Different versions of the same gene. If a dominant allele is present the dominant characteristic is seen. For the recessive characteristic to be seen, both alleles must be recessive Homozygous = 1 identical alleles Heterozygous = 2 different alleles Genotype = genetic makeup Phenotype = Characteristics seen red-green colour blindness, sickle cell anaemia cystic fibrosis. Faulty genes, most of which are recessive • mutations (changes to the genes) • gamete formation • fertilisation. 105. Name three disorders that are inherited: 106. What causes genetic disorders? 107. Describe three causes of genetic variation 108. How do the chromosomes determine the sex of mammals? 109. Why do we see equal numbers of male and female children? XX (female) XY (male) A father is equally likely to pass on an X or Y chromosome to their child
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