Brigham Volume XIV, No. 3 • May /June 2006 and W o m e n ’ s H o s p i ta l , H a r v a r d M e d i c a l S c h o o l http://etherweb.bwh.harvard.edu/record To Have and To Hold BWH Biomedical Engineering —10 Things You Always Wanted to Know by Lawrence Tsen, M.D. “To lose a brother is to lose someone with whom you can share the experience of growing old, who is supposed to bring you a sister-in-law and nieces and nephews, creatures to people the tree of your life and give it new branches. by Evelyn Fan, M.H.Sc., Clinical Engineer 1. What Is the Vision and Purpose of Biomedical Engineering? The Director of Partners Biomedical Engineering, Dr. Jeff Cooper, is well known for his work in anesthesia patient safety. Our mission statement is “It is our goal that no patient is harmed by the application of a medical device To lose your mother…well, that is like losing the sun above you.” within our Partners’ sphere of influence.” —Yann Martel, Life of Pi We accomplish this through: rom the first flicker of morning consciousness Evaluation of Technology: Our engineers work to underuntil sleep steals back into our nighttime grey matstand the use model of clinical practice in the hospital, ter, we seemingly have every moment occupied. We’re and to match market technology for safe and efficacious locked in the Sisyphusian struggle of pushing too many application. tasks into too little time. The modern-day hospital environment pressurizes this process by a cacophony of patient and Scheduled Maintenance: We check medical equipment at regular intervals to prevent future problems and to ensure provider needs—chirping monitors, epileptic beepers, and angrily reproducing emails. A recent event in our Anesthe- devices are safe to use. sia/Brigham family, however, should make us reflect more On-Call Response: We assist clinicians with problems deeply on the heroic struggles taking place around us; we while devices are in clinical use. are all exposed, more than in any other career path, to the Equipment Repair: We repair devices when malfunctions very real tension between sickness and health; birth and occur so that they function properly and can be put back death; presence and absence. into service. continued on page To lose your father is to lose the one whose guidance and help you seek, who supports you like a tree trunk supports its branches. F Features To Have and To Hold —Lawrence Tsen BWH Biomedical Engineering —Evelyn Fan Departments News & Updates Academic Activities & Achievements Publications Lectures Regular Rounds: By working with clinical staff to better understand the use model of devices, we strive to prevent problems before they occur. Education: We work with clinical staff to educate them on the safe and proper use of medical devices. Device Recall/Alerts & Safety Reports: We follow up with manufacturers on medical device recalls/ alerts reported by the FDA and other sources, and perform investigations to ensure devices are safe for staff and patients. In short, BWH Biomedical Engineering strives to provide technology solutions that advance the care and safety of patients, while making sure that equipment is safe for clinical staff to use. continued on page The Anesthesia Record • May/June 2006 To Have and to Hold (from page ) Without rubbing the philosopher’s stone too hard, if you were not able to return tomorrow, how would your colleagues, friends, and family members remember you? Would they comment on the many things that overwhelmed your schedule, or would they share what you did for them, as well as for others? Excluding patients, where our involvement is partially mandated by our working relationship, have your actions today affected the life of someone else… a spouse, a child, a colleague, a student, a cashier, or a random person? Would the other person acknowledge your action(s)? And would their reactions be positive? The Nobel Prize–winning author J.M. Coetzee, as a 15-year old boy in Cape Town, South Africa, mentioned an afternoon in his family’s garden when “everything changed.” The philosopher Martin Buber stepped away from the brink of suicide through a suddenly gained insight on human existence. What was responsible for these lifealtering transitions? —Johann Sebastian Bach. More specifically, listening to the 24 keyboard preludes and fugues in all of the major and minor scales which he composed in 1722 as The Well-Tempered Clavier. When listened to intensely, the “character” Bach found in each note can be experienced as solace; this isolated resting place was experienced to such an extent by the pianist and composer Robert Schumann that he advised all musicians to sample these pieces as their daily bread. And Goethe, experiencing these Bach pieces for the first time, said “It is as if the eternal harmony were conversing within itself, as it may have done in the bosom of God just before the creation of the world.” “Have you made a goal-directed commitment to a colleague?” Alas, only precious few of us are virtuosos able to toss the values of symmetry, transparency, and grace and end up with a masterpiece certain to move others. Thankfully, positive outcomes only rarely need to evolve from masterpieces; in most cases, however, such results require sacrifice and risk. Enabling such outcomes for others involves the sacrifice of your precious time and invokes the risk that the intended result may not occur. The basis of these outcomes however, begins with a commitment and an agreement on what the desired outcome should be. When was the last time you made a commitment to someone, other than your spouse or significant other? Have you made a goal-directed commitment to a colleague? Such relationships are profoundly rewarding for both participants, and can help encourage more such relationships; ultimately, they make our department and hospital an even better place. Examples of commitments made with colleagues include initiating a research project, inviting participation into a professional committee or group, or improving lecturing skills. Among individuals with similar skill sets, it can mean dividing work so everyone goes home “Measurable goals allow you to assess your progress, stay on track and inspire you to continue.” at a reasonable time, working on weekends to accommodate a colleague’s more difficult home schedule, or helping a colleague find a more optimal job situation. These activities may simply be called “helping,” but I believe they go beyond that; they represent an ongoing, committed process of attempting to ensure positive outcomes with and for your colleague, even when it’s neither convenient nor of direct value to you. When working with others, it is particularly important to acknowledge the goals of your commitment; establishing “SMART” goals, which I have altered to mean Specific, Measurable, Actionable, Realistic, and Time-based, may be of value. Specific goals involve the “who, what, where, when, and why” questions; instead of a general “I want to get in better shape,” it’s a “I will install an elliptical trainer in my basement and work out 3 times a week at 4 a.m. to improve my cardiovascular health.” Measurable goals allow you to assess your progress, stay on track and inspire you to continue. Actionable goals contain items that can be physically acted upon, often in a step-wise fashion, for instance, “What can I do today, or next time, to bring this project closer to completion?” Realistic goals incorporate you and your colleague’s attitudes, abilities, skills, and the capacity to reach the desired outcome. Finally, time-based goals are those that have a pre-defined calendar for completing the task. SMART goal-oriented commitments with colleagues can accomplish a number of direct and indirect outcomes. Life will hopefully become more meaningful, allowing us to be more like Bach, and less like the case of Ivan Ilych Golovin, a fictitious high court judge in St. Petersburg. In the Death of Ivan Ilych, Tolstoy tells us that Golovin lives a carefree life which is “most simple and most ordinary…and therefore, most terrible”; he has squandered his life by pursuing the insubstantial. Only when a mysterious and growing terminal pain enters his life does Golovin begin to reexamine his life, his actions in the past and the people around him. Let us not wait until a catastrophe absconds with our health before we begin working with others in a meaningful, committed, goal-oriented way. Instead, let us appreciate that the sands of time are shifting quickly, and that the time to improve our lives, and others’, is now. In this way, perhaps the life that we lead will truly be a masterpiece capable of inspiration. F Discography: Glenn Gould, piano: The Well-Tempered Clavier. Sony, 1963-65; reissued 1993. Regarded as a laser-like etching of Bach’s musical lines, with a flood of light and quirkiness. Daniel Barenboim, piano: The Well-Tempered Clavier, Book 1. Warner Classics, 2004. Considered a “romantic interpretation,” this recording may not sit well with purists, but is nonetheless a warmer, and enjoyable performance. Books: Yann Martel: Life of Pi, Winner of the 2002 Man Booker Prize for fiction. Harcourt Books, 2001. Leo Tolstoy: The Death of Ivan Ilyich. 1886 Lawrence Tsen is Associate Professor of Anesthesia and Director of Anesthesia, Center for Reproductive Medicine Brigham and Women’s Hospital Tr a n s i t i o n s… In a department such as our own, with several hundred faculty, residents, researchers, and support staff strewn over various locations, few individuals have regular contact with the larger whole. One who does is Ernie Chislom, whose duties and daily perambulations put him in touch with dozens of people, and, over the course of a week, with hundreds. Ernie’s tasks go well beyond the nominal title “mailroom clerk.” He also orders supplies, keeps the duty room stocked, copies articles at Countway Library, does errands as needed, and makes sure people get fed—and that’s the short list. Estimating that he spends 80% of his time on the go, Ernie enjoys the activity and variety of his workday—his motto is “Whatever makes this department better, I want to do.” Over the six and a half years Ernie’s been with us, we’ve all experienced his enthusiasm and energy, and the good will and cheer he brings to every facet of the day. While sports fans in particular might feel a sense of loss, Ernie extends warmth and friendliness to everyone, and his July departure shall doubtless leave us all a bit distraught. Immediate plans are to take a few months off, perhaps traveling with wife, Elwanda, and enjoying the company of Cyrus Anne, his Rottweiler/Shepherd hybrid. Ernie plans to let the rest and relaxation help guide him to a decision on “what next?” For now, after 36 years in the workforce, he’s eagerly looking forward to a well-deserved break. Our thanks and best wishes. The Anesthesia Record • May/June 2006 BWH Biomedical Engineering (from page ) 2. What Areas Does the OR Team Cover? Three BWH Biomedical Engineering teams cover the wide range of medical equipment at BWH: the OR Team, the Monitoring Team, and the Infusion Technology Team. The OR Team provides anesthesia and surgical technology support for the following areas: Main Operating Rooms, Endoscopy, PACU, Day Surgery, Pre-Op, Magnetic Resonance Therapy (MRT), and Ambulatory Treatment. In addition, we support the following remote anesthesia locations: Magnetic Resonance Imaging (MRI), Labor and Delivery (L&D), In-Vitro Fertilization (IVF), Family Planning, the Cath Lab and Radiation Oncology, and Interventional Radiology (INR). 3. How Many Medical Devices Does Biomedical Engineering Manage? We currently support over 15,000 devices hospital-wide. Devices classified as Life-Support/High-Risk/Normal-Risk require scheduled maintenance 1 to 2 times a year. Some examples of Life-Support equipment include anesthesia machines, cardiac bypass machines, and defibrillators. Examples of High-Risk devices include electrosurgical units, lasers, and vaporizers. The JCAHO requirement for up-to-date compliance is 100% for Life-Support devices and 95% for High-Risk and Normal-Risk devices. You can help us guarantee compliance by arranging for access to equipment when it is due for service. 4. How Does Biomedical Engineering Manage All This Equipment? Partners Biomedical Engineering (PBME) has developed a Medical Equipment Management Plan (MEMP), which is designed to minimize the risk of using patient-care equipment through inspection, preventive/scheduled maintenance, and education of those who use and maintain the equipment. The Equipment Management Committee (EMC) is a PBME committee that meets to ensure that medical equipment is managed under MEMP. Ernst Daniel, Clinical Engineer, and Trevor Roberts, Senior BMET, represent the OR Team on this committee. All patient-care equipment in the MEMP are assessed using a risk-classification system that addresses the equipment function, clinical application, preventive-maintenance requirements, likelihood of equipment failure based on history, and environment of use. Based on the calculated score for each device, the resulting risk classification determines the scheduled maintenance (SM) interval. As mentioned earlier, anesthesia machines are classified as Life-Support devices. We manage 60 anesthesia machines, each of which requires scheduled maintenance twice a year. 5. How Does Biomedical Engineering Keep Track of It All? Partners Biomedical Engineering uses a database to track the medical equipment we manage. Each device is assigned a unique control number and has an associated equipment profile. Our equipment database stores information such as the work history of a device, which can provide valuable data for analysis. This history also includes the details of user-related problems specific to a device, so when you call us to a room, the details of that call become part of the device’s history. This enables Biomedical Engineering to track problems associated with a particular device. This database allows us to learn about repeated failures, which can be useful for predicting failures, deciding on future capital-equipment purchases, and gaining insights for planning equipment life cycles and servicing equipment. 6. Who Is on the OR Team? See page 5. We also currently have an open BMET position. 7. What Does Biomedical Engineering Do? Doesn’t “Biomed” Just Fix Things? Clinical Engineers (CEs) are involved in the support of complex patient-care technology or systems, and are the technical resource for the hospital and clinicians. Clinical engineers evaluate and assess patient-care technology, and are involved in project work, equipment installations, deployment, and capital-equipment purchases. They ensure that medical devices are managed properly under the MEMP, and collaborate with staff on the effective in-service for the use of patient-care technology. Clinical engineers are also involved in following up with safety reports, device failures, and recalls. Off-hours a clinical engineer is on-call and available for emergencies. Biomedical Engineering Technicians (BMETs) repair, maintain, and perform scheduled maintenance on patientcare equipment. They also provide in-house on-call response to help clinical staff troubleshoot and diagnose equipment-related problems. After-hours and on weekends, a technician is on-call and available for emergencies. BMETs also assist clinical engineers with equipment installations. The OR Biomedical Engineering Team Claire Cabral, Sr. BMET Ernst Daniel, Clinical Engineer Evelyn Fan, Clinical Engineer Eddie Holmes, Facilities Technician Ross Jacques, BMET Anthony Johnson, BMET Dr. Jim Philip, Medical Liaison Trevor Roberts, Sr. BMET Biomedical Engineering OR Coverage In-house coverage hours: 6:00am – 5:00pm, Monday - Friday OR Biomed extension: 31987 (for non-urgent calls) OR Biomed pager: 11055 (for urgent calls) Sterilizer/CPD calls to be paged to: 28889 Facilities Technician pager: 11005 After hours/weekends pager: 11055 (for emergencies) Maximum response time for call-back after hours/ weekends: 20 minutes (The technician will try his/her best to assist you over the phone so that you can get the help you need quickly) Maximum response time for in-house support after hours/weekends: 2 hrs The Anesthesia Record • May/June 2006 BWH Biomedical Engineering (from page ) Facilities Technicians repair, maintain, and perform scheduled maintenance on sterilizers, surgical lights, OR tables, and CPD equipment. They also provide in-house on-call response to help clinical staff troubleshoot and diagnose equipment-related problems. After-hours and on weekends, a facilities technician is on-call and available for emergencies. The Medical Liaison acts as a clinical resource for the OR Team, and an engineering and technical resource for clinicians, thereby serving as a liaison between clinical staff and Biomedical Engineering. 8. Who Else Does Biomedical Engineering Work With? Since patient-care technology pervades the entire hospital, Biomedical Engineering works with staff from many other departments, including Anesthesia Technicians, Equipment Technicians, Equipment Pool, Engineering, OR Clinical Support Services (OR/CSS), Central Processing Department (CPD), Anesthesia, Nursing, Infection Control, Perfusion, Environmental Affairs, Materials Management, Patient Safety, Risk Management, and Information Systems, just to name a few. 9. Where Is Biomedical Engineering Located, and When Is It Open? Most of the time, the BWH OR Biomedical Engineering Team can be found in the main ORs on rounds, assisting staff with equipment-related problems during the day. But our permanent home is the OR Biomedical Engineering Shop (which is located at LL-L1-206, between Interventional Radiology and Medical Records/Nesson Ambulatory elevators). From the main Anesthesia offices, turn left at the vending machines and left again after the ASB I elevators. Our shop is down the hall on the right. See the table on page 5 for further information. 10. Tips from Biomedical Engineering As a teaching hospital, Brigham and Women’s provides exposure to many types of technology. Biomedical Engineering currently supports a fleet of 60 anesthesia machines, 32 of which are manufactured by GE DatexOhmeda, and 28 by Drager Medical. There are, in turn, a variety of models: GE Datex-Ohmeda Drager Medical 6 Aestiva 3000 1 Narkomed MRI 1 Aestiva 5 2 Narkomed MRI-2 2 Excel 210 3 Fabius Tiro 4 Mod II 22 Fabius GS 3 Mod II Plus 7 Mod CD 9 Mod SE The most important tip we have for you is to do the FDA Anesthesia Checkout! Each anesthesia machine has an FDA Anesthesia Apparatus Checkout Recommendations card attached to it, with model-specific instructions for performing the checkout procedure. Doing this checkout will help to determine if there are any problems with your machine before the case starts. If problems are discovered, needless to say it’s much easier for us to help you find a solution before the patient is intubated, rather than when the patient is already being ventilated. The most important parts of the checkout are: 1) Low-pressure leak test 2) Leak test of breathing system/high-pressure leak test 3) O2 sensor calibration 4) Flow sensor calibration 5) Check for moisture (not part of the checkout, but valuable to do in preventing problems, especially when using low flows or for long cases). For Datex- Ohmeda machines, check for droplets on the domes and in the flow sensor tubing. For the Fabius GS, ensure the water traps are empty. If you need assistance in performing any of the tests for the anesthesia checkout, or if you have any questions, please feel free to ask anyone on our team. F The Anesthesia Record is published bimonthly by the Department of Anesthesiology, Perioperative and Pain Medicine of Brigham and Women’s Hospital, Boston, MA. It is available online at http://etherweb.bwh.harvard.edu/record Editor: Naila Moghul, M.D.; Assistant Editor: Michael Joyce; Design/Layout: Jamie Bell; Secretary: Sharon Dube. Comments and suggestions are always welcome and may be forwarded to the editor at [email protected]. News & Updates Omid Farokhzad, M.D., was featured on ABC News regarding nanotechnology research. Dr. Farokhzad and his colleague Robert Langer at MIT designed tiny chemotherapy-loaded shells that are only attracted to cancerous cells. These smart nanoparticle shells are studded with chemical homing devices that can tell cells apart from what’s on their surface. “The surface of the cell that has now become cancerous looks different. It has other molecules on its surface that are absent on the surface of the normal cells,” explains Farokhzad. As reported in Proceedings of the National Academy of Sciences (PNAS), the researchers compared treatment with these chemo-loaded nanoparticles to regular chemotherapy in mice with prostate cancer. They found that the mice treated with a single dose of the nanoparticles had significantly reduced tumors—in fact, most of the mice had total tumor elimination. By contrast, the group given a dose of regular chemotherapy had no tumor reduction and a high mortality rate. With luck, such nanoparticle therapy is a step in the right direction. The researchers say that safety trials in men with prostate cancer might be ready in two to three years. Farokhzad and Langer’s research was published in the April 18, 2006 issue of PNAS, and was funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB), the National Cancer Institute (NCI), and the David Koch Cancer Research Fund. Thuc Tran, M.D., a 2003 BWH Anesthesiology graduate, was recently instrumental in saving the life of a fellow high school alumnus who collapsed without a pulse during an alumni softball tournament at Creighton Prep, in Omaha, Nebraska. According to the Omaha World-Herald, Dr. Tran used a defibrillator to restore a heart rhythm, and established an airway by threading a tube through Mike Ricketts’s mouth and trachea. The newspaper highlighted a Vietnam connection linking doctor and patient: Thuc Tran was born in Vietnam, and Mike Ricketts is a veteran of the Vietnam War. To which we would add a further coincidence: Dr. Tran and Dr. Charles Vacanti, our department chairman, are both graduates of Creighton Prep. It’s obviously a school that’s doing something right. The full text of the article can be viewed at: http://etherweb.bwh.harvard.edu/anes- rec/media/TTran_June_06.pdf Academic Activities & Achievements The department would like to congratulate the following BWH residents, fellows, and staff alumni who were certified as Diplomates of the American Board of Anesthesiology after the Spring oral examinations: The Anesthesia Record • May/June 2006 James “Jake” Harry Abernathy, Hammam Hadi Akbik, James Michael Anton, Nicole A. Boler, Daniel Castillo, Theresa S. Chang, Daniel S. Choi, Daniel Anthony Diedrich, Elliott S. Farber, Melissa W. Hull, Stefan E. Jahng, John Khozozian, Pei-Lin Kim, Francis W. Lau, Ursula M. Marks, Andrew E. McQuide, Michael Nurok, Anish S. Patel, Neil P. Ray, Beverly Jean Stickles, Nelson L. Thaemert, Luis Etienne Tollinche, Assia Todorova Valovska, and Sarah. H. Wiser. We are proud of each and every one! There were 810 new Diplomates certified—BWH had a hand in 24, roughly 3% of the total! Vladimir Formanek, M.D., David Hepner, M.D., Annette Mizuguchi, M.D., Naila Moghul, M.D., and Monica Sa Rego, M.D. (pictured), were each awarded Faculty Awards in Excellence for 2006. The Department established these awards six years ago to honor faculty members for outstanding contributions in clinical practice, research, education, administration, service and/or professionalism. Ru-Rong Ji, Ph.D., Assistant Professor of Anaesthesia in the Pain Research Center, has been awarded a five-year grant totaling $1.98 million from the National Institutes of Health, National Institute of Dental and Craniofacial Research to study “Neuronal and glial interactions of neuropathic pain.” Congratulations Dr. Ji! James Philip, M.D., was recently elected 2006 Teacher of the Year by the Department’s residents. The award was presented by last year’s chief residents at the residents’ graduation breakfast held on June 21. Stanton Shernan, M.D., was elected to the Board of Directors for the American Society of Echocardiography. Gregory Stahl, Ph.D., was awarded a grant, 2006–2011 NIH/RO1 DE017821, co-Principal Investigator, to study “Microglia, complement, and pain.” Lawrence Tsen, M.D., was elected Second Vice President, Society for Obstetric Anesthesia and Perinatology, at the organization’s Annual Meeting in Hollywood, FL, in May. This position progresses through the subsequent annually held positions of First Vice President, President-Elect, and then President of the Society. Publications Hindler K, Eltzschig HK, Fox AA, Body SC, Shernan SK, Collard CD. Influence of statins on perioperative outcomes. Journal of Cardiothoracic Vascular Anesthesiology 2006;20:251–58. Lemos P, Jarrett P, Philip B, eds. Day Surgery: Development and Practice. International Association for Ambulatory Surgery, London, 2006. Roos A, Rastaldi MP, Calvaresi N, Oortwifn BD, Schlagwein N, van Gijlswijk-Janssen DJ, Stahl GL, Matsushita M, Fujita T, van Kooten C, Daha MR. Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease. Journal of the American Society of Nephrology 2006;17:1724–34. Harboe M, Garred P, Borgen MS, Stahl GL, Roos A, Mollnes TE. Design of a complement lectin pathway specific activation system applicable at low serum dilutions. Clinical and Experimental Immunology 2006;144:512–20. Roos A, Rastaldi MP, Calvaresi N, Oortwifn BD, Schlagwein N, van Gijlswijk-Janssen DJ, Stahl GL, Matsushita M, Fujita T, van Kooten C, Daha MR. Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease. Journal of the American Society of Nephrology 2006;17:1724–34. Wasan A, Kaptchuk TJ, Davar G, Jamison RN. The association between psychopathology and placebo analgesia in patients with discogenic low back pain. Pain Medicine 2006;7:217–28. Lectures Stanton Shernan, M.D., represented the Society of Cardiovascular Anesthesiologists at the American Institute of Ultrasound in Medicine’s (A.I.U.M.) Ultrasound Practice Forum held in Washington, DC, April 21. The A.I.U.M is a multidisciplinary organization dedicated to advancing the art and science of ultrasound in medicine and research. Gregory Stahl, Ph.D., was an invited speaker at the 4th International Innate Immunity meeting in Corfu, Greece. He lectured on the Role of the MBL-Dependent Lectin Pathway in Ischemia-Reperfusion Injury. Gary Strichartz, Ph.D., Vice-Chair for Research and Director, Pain Research Center, participated in the American Pain Society’s Annual Meeting in San Antonio, TX. He presented a lecture titled Studies on the Mechanisms by Which Systemic Lidocaine Relieves Neuropathic Pain in a workshop on Systemic Lidocaine: Does It Have a Place in Pain Management? Lawrence Tsen, M.D., was Visiting Professor, Department of Anesthesiology, The Ohio State University Medical Center on June 10–12 and gave the following presentations: Grand Rounds: Hail Cesar: Anesthesia for Cesarean Delivery; Lecture: Defend Your Epidural Technique; and Combined Anesthesia, Obstetrics, and Pediatrics Morbidity and Mortality Conference: Postpartum Hemorrhage. F The following BWH staff members presented lectures and abstracts at the recently held 28th Annual Meeting of the Society of Cardiovascular Anesthesiologists: • Simon Body, M.D., Amanda Fox, M.D., John Fox, M.D., Elmer Choi, M.D., Stanton Shernan, M.D., with J. Brechman and C.D. Collard: Echocardiographic Classification of Thoracic Aortic Atherosclerosis and Its Impact on Cardiac Surgical Technique. • Amanda Fox, M.D.: Indications and Intraoperative Considerations for VAD Placement. • Douglas Shook, M.D.: Mitral Valve Dysfunction Following Mitral Repair Surgery. • Stanton Shernan, M.D.: Mitral Valve Repair: Assessing Feasibility, Adequacy and Complications of Mitral Valve Reconstruction and Attenuating the Systemic Inflammatory Response to CPB as a Means for Improving Outcomes: Fact or Fiction? Ru-Rong Ji, Ph.D., chaired a symposium on Spinal Second Messenger Pathways under Different Pain Conditions. He was also a speaker for the symposium at the Annual American Pain Society Conference held in San Antonio, TX, May 3–6. We’re off for the summer! Watch for the next issue of The Record this fall.
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