Major surgical resections England, 2004-2006 national cancer intelligence network Major surgical resections England, 2004-2006 www.ncin.org.uk Contents Introduction Page 3 Page 4 Page 6 Page 7 Page 8 Background Methods Summary of results Limitations Next steps NHS treated patients with a record of a major resection, by site Page 10 Page 12 Page 14 Page 16 C15: Oesophagus C16: Stomach C22: Liver C25: Pancreas Page 18 C18-C20: Colorectal Page 20 C33-C34: Trachea, bronchus and lung Page 22 C50: Breast Page 24 Page 26 Page 28 C53: Cervix C54-C55 : Uterus C56: Ovary Page 30 Page 32 Page 34 C61 : Prostate C64-66 & C68 : Kidney C67: Bladder Glossary Page 36 Page 38 Page 39 Glossary Appendix 1: Patients linked to HES Appendix 2: OPCS-4 codes assigned to each site 1 2 Introduction Background Surgery is the treatment that has the greatest impact on long term survival in most types of cancer. It can also serve the purpose of significantly improving symptoms, even in situations where long term survival is unrealistic. A more detailed understanding of the patterns of surgical treatments in cancer is therefore vital to efforts to improve outcomes for cancer patients. The need to develop better knowledge and understanding of treatment was a central aim of the Cancer Reform Strategy. This project is the first attempt to look in more detail at surgical treatment for patients across a wide variety of cancer types in England. This report is best seen as the beginning of a process in which we aim, over time, to relate treatment rates to survival and other outcomes, to establish ‘benchmarks’ for good practice and to provide data both to health care providers and commissioners that we hope will help drive up standards of care. The main source of routine data collection of surgical procedures within the NHS is the Hospital Episode Statistics (HES) dataset, collected though trusts submitting relevant data for their patients. These data are used for the reimbursement of trusts for their surgical activity. Recently, the National Cancer Intelligence Network (NCIN) facilitated the linkage between the national cancer registry data held by the English cancer registries, and an extract of all HES records relating to cancer patients. This has resulted in the National Cancer Data Repository (NCDR), enabling the analyses presented in this report. The National Cancer Data Repository holds cancer registration data for the whole of England combined with over 10 million individual entries of hospital episodes. This provides an unparalleled resource for exploring hypotheses and evaluating quality of care. Further information about the National Cancer Data Repository is available from the NCIN website www.ncin.org.uk. The proportion of patients who undergo surgical operations as part of their treatment is available nationally for bowel, head and neck, lung, oesophago-gastric cancers and mastectomy and breast reconstruction through national cancer audits. See http://www.ic.nhs.uk for more details. Analyses by cancer networks in these audit reports are either the network where the patient is first seen in secondary care (usually the Multi-Disciplinary Team) or in which patients receive their treatment. In the work presented here, we have used the area of residence of patients in the analyses, which will result in some apparent discrepancies at a local level if the results are compared directly with audit data. Their reports may also cover different time periods. In addition, the results presented in this report may differ because of the use of different surgical procedure codes from those used in the national audits. This is because, for the present analysis, we have chosen to focus on what the clinical experts in their respective fields have identified as the relevant ‘Major Surgical Procedures’, some of which may well be carried out with ‘palliative’ rather than ‘curative’ intent. This report represents a significant step forward in providing national level analyses for the surgical treatment of a wide range of common cancer sites using routine information on surgical procedures derived from HES. This is the first report that brings together information of this nature using a common methodology and produces a common set of outputs specifically for major resections across such a wide range of cancer types. By bringing together cancer registrations with information regarding operations and procedures undertaken within the NHS, we can present analyses of the data that is available and start to ask questions as to why any apparent differences are seen. 3 This is the first step in understanding variations in surgical treatment which we hope will provide the intelligence to raise standards of care and help improve outcomes for cancer patients. In undertaking this analysis, we attempted to answer the following questions: • Is it possible to use routine HES data to ascertain the proportion of patients who received a major resection as part of their treatment? • Are there differences in surgical rates between the sexes, age groups and those in different deprivation quintiles? • What is the variation across the country based on the cancer network to which patients are assigned using their postcode of residence? Methods The primary aim of this report was to produce a first exploratory analysis using routine data from hospitals to determine the percentage of patients who have a record of a major resection in England and whether any variation between inequality groups exist. Major resections were classified as nondiagnostic surgical operations which would be carried out with intent to remove the tumour. The HES database contains records for every in-patient and/or day case stay for each patient attending an NHS hospital in England and includes information regarding the procedures, operations and corresponding dates performed during each episode. Each episode can contain up to 12 different codes describing the procedure or operation that a patient underwent. Operations and procedures are recorded using a classification system called OPCS. All OPCS codes and their descriptions used for each site are included in the appendix of this report. Clinicians from the NCIN’s Site Specific Clinical Reference Groups (SSCRGs) and staff from cancer registries in England were involved in this work and helped to determine which relevant OPCS codes should be included as a major resection for each cancer site, given that a patient had a diagnosis of cancer. For certain sites there are diagnostic procedures which may also remove the tumour, for example loop and cone biopsies for cervical cancer. However, without data such as stage of disease at diagnosis, it is not possible to say retrospectively whether the tumour would have been removed and therefore these operations were not included as “major resections”. Patients with certain tumours may also undergo surgery that won’t remove the tumour but will instead aim to debulk the tumour before radiotherapy or chemotherapy. Therefore, the percentage of patients who have received surgery as part of their care may well be higher for some sites than the percentage of patients who receive a major resection as presented in this initial report. All patients diagnosed with a malignant neoplasm from 2004 to 2006 (inclusive) were extracted from the NCDR in January 2010 for cancer of the oesophagus (C15), stomach (C16), liver (C22), pancreas (C25), colorectal (C18-C20), lung (C33-C34), breast (C50), cervix (C53), uterus (C54-C55), ovary (C56), prostate (C61), kidney (C64-C66 & C68) and bladder (C67). All codes in brackets relate to the ICD-10 codes included for each site. 4 The National Cancer Data repository also holds data obtained from linking patients with the Hospital Episode Statistics Database (HES). All linked HES records from 2003 to 2007 were extracted for cancer patients from the national cancer data repository in October 2010. All OPCS procedures from HES for a given patient were included in the analysis. A patient was either classified as having a record of a major resection or not. It is possible that patients had a record of more than one OPCS code that was assigned as a major resection for their treatment. These patients have been included once in the analyses as having received a major resection. A timeframe of 30 days before diagnosis date and up to six months post diagnosis was used to restrict the surgery to the relevant cancer diagnosis and not a recurrence. For cancers of the breast, uterus, ovary and cervix, a period of up to one year post diagnosis was used. This is because, for these cancers, patients may undergo a course of chemotherapy, radiotherapy or both, before a major resection is performed. Any procedure outside the allocated timeframe was not attributed to that diagnosis and therefore excluded from these analyses. Exclusions were also made where a patient was diagnosed as a result of being registered solely on the basis of a death certificate (Death Certificate Only registration – DCO). As DCO registrations are unlikely to have known about their tumour before their death, it would not be appropriate to include them within these analyses. The proportion of patients classified as a DCO varies with site. In addition, any records with missing information regarding date of diagnosis, place of residence at diagnosis or age of patient were also excluded from the analysis. The quality of our data has not made it possible for us to attempt to correct the findings for the stage of disease or for co-morbidity, although we have examined the effects of age and socio-economic deprivation As data is only available for patients treated in NHS hospitals, any patients who could not be matched to at least one hospital episode were also excluded from the analysis as we did not know whether they may have received a major resection outside of the NHS. Data for patients who are treated privately are not currently available. The percentage of patients who did not have a linked HES record varies by cancer site from 27% for prostate cancer to 3% for oesophageal cancer. Table 1 shows the breakdown by site and Appendix 1 shows the percentage of matched patients by cancer site and by cancer network. 5 Table 1: Percentage of Non-DCO cancer registrations linked to a HES record, by cancer site, patients diagnosed 2004-06, with HES up to 2007. Cancer Site oesophagus stomach liver pancreas colorectal lung breast cervix ovary uterus prostate kidney bladder Number of NonDCO patients 18,458 18,771 6,732 17,490 85,513 87,703 110,808 6,765 15,852 16,880 87,874 17,649 24,508 Non-DCO patients linked to HES 17,839 17,830 6,056 16,074 80,690 80,522 97,690 6,007 14,444 15,374 63,940 16,314 23,562 Percent of patients linked to HES 97% 95% 90% 92% 94% 92% 88% 89% 91% 91% 73% 92% 96% Summary of results For all cancer sites, there was a decrease in the proportion of patients undergoing a major resection for older patients, with less than 2% of patients aged 80+ having a record of a major resection for six of the thirteen cancer sites analysed. There was evidence of small but significant decreases in the proportion of patients receiving a major resection in the more deprived socio-economic groups and also of variation in surgical rates between cancer networks. However, further work is required in order to the better understand the clinical significance of these observations since other factors such as late diagnosis (i.e. stage of disease) and co-morbidities could contribute to these differences. For cancers of the oesophagus, stomach, bladder, prostate, lung, pancreas and liver, less than 16% had a record of a major resection as part of their treatment. For liver cancer, only 6% of all patients were recorded as having undergone a major resection within NHS hospitals. With the exception of stomach cancer, less than 2% of patients aged over 80 had a record of a major resection in any of these cancer sites. Large falls in the percentage of patients with a record of a major resection by age were seen for ovarian, kidney and cervical cancer. For patients aged 40-49 compared to patients aged 80+, the proportion decreased from 82% to 26% for ovarian, from 78% to 29% for kidney and from 58% to 10% for cervical cancer. The highest percentage of patients aged 80 and over with a record of a major resection was seen in uterine cancer where a resection rate of 65% of NHS treated patients was seen. Variation by deprivation quintile was not adjusted for age or other case-mix factors. Further work is therefore required to examine whether there are particular sub-groups of patients where there are real differences related to deprivation that may be hidden by this high level analysis. 6 The largest difference by deprivation quintile was seen for cervical cancer, with a gap of 10 percentage points between the least deprived and the most deprived. This gap can be expressed as a change of 2.3 percentage points per deprivation quintile and was statistically significant. Further analyses are required to try and define the reasons underlying this observation. Differences in major surgery rates by deprivation quintile were also seen for cancers of the breast, colorectal (males and females), liver (f), lung (m), oesophagus (m), pancreas (m) and prostate. The differences however were relatively small for these sites, with the largest deprivation gap seen for oesophageal cancer with a difference of 1.3 percentage points per deprivation quintile. Not having access to data for patients treated in the private setting may also result in an underestimation of the “deprivation gap” in major resections since private cancer surgery will be most frequent in the least deprived socio-economic groups. Results analysed by cancer network also show that variation exists between the areas of residence of patients which cannot be explained by differences in the age structure of the populations. These results are presented to encourage further local and national examination of the reasons behind these apparent geographical differences in surgical resection rates. Only three of the sites, breast, uterus and liver, had all cancer networks within limits of expected variation when differences in age structures have been taken into account. For lung cancer, six cancer networks fell below the lower confidence limit and four cancer networks were above the upper confidence limit. This first analysis simply shows that variations do exist and should not, at this stage, be interpreted as necessarily demonstrating good or bad practice. Limitations There are various factors which limit our ability to interpret these data. The most important of which is that we have not been able to make case-mix adjustments of the surgical rates for the stage of disease since this is not universally recorded for all cancer sites at a national level. There are surgical procedures which it is not possible to assign as ‘major’ resections without knowing the stage of disease for that patient. For early stage cervical patients, for example, operations which are coded as biopsies would have been undertaken to remove the tumour, whereas for patients with later stage disease, this would be a diagnostic procedure. There are also concerns over the quality of data within HES which was not established with the direct intention of analysing the details of surgical operations, rather as a tool for reimbursement. However, it is a large scale and routinely available data source which we can use to try and gain a better understanding of cancer patients’ treatment. It is possible that there is some systematic variation in the way different Trusts code their procedures which could also explain some of the apparent variation at Network level. These analyses have also not taken into account co-morbidities of patients which will affect the decision to treat and which could vary in their impact at regional level. The NCIN is committed to further work on this topic which we hope will allow for the adjustment of such data for co-morbidity. In order to use such data to understand differences in clinical outcomes for patients for the future, we need to ensure that surgical procedures are coded consistently. It has become clear during the course of this work that there is significant scope for the rationalisation of how surgical procedure codes are used in this context and clinicians need to take more responsibility for how their activity is recorded. 7 Next steps These data provide an overview of the available data that is held regarding major surgical resections in England. However, this is just a basis to instigate an exploration of which questions need answering, and how the data can be recorded and shared in order to allow further analyses to be made. The results provide further evidence for the need for high quality cancer stage, co-morbidity and treatment data in order to explore the reasons for any variation. 1) Derive Charlson Indices from IP HES to examine the impact of co-morbidity on the variation. 2) Work with the clinical community via the NCIN’s SSCRGs to engage with the coding section of Connecting for Health to try and improve the way that surgical procedures in cancer are coded. 3) Carry out more in-depth analyses of the impact of deprivation on surgical rates. 4) Try and establish the relationship between surgical treatment rates and outcomes, especially survival. 5) Make more systematic and ongoing links with the National Cancer Audits. 6) Try and find ways of examining the whole ‘treatment pathway’ for cancer patients; in other words, examine the role of surgery in combination with other oncological treatments. 7) Use the data to help support module 5 of the International Cancer Benchmarking Project; working towards internationally agreed ‘benchmarks’ of good practice. 8 Acknowledgements This analysis was led by Jon Shelton. Thanks are due to Dr Mick Peake, Clinical Lead, NCIN and all the Site-Specific Clinical Reference Group lead clinicians for their work in this project, especially the involvement of Mr Bill Allum, Mr Andy Nordin, Mr Roger Kockelbergh, Prof. Paul Finan, and Mr Martin Lee, who have played a prominent role in the thinking behind this report. Thanks are also due to many members of lead cancer registries who have helped enable these analyses, with thanks especially to Eva Morris, Gill Lawrence, Henrik Møller, Louise Hollingworth, David Meechan, Alexandra Thackery, Elizabeth Davies, Victoria Coupland, Luke Hounsome, Sean McPhail and David Greenberg. Particular thanks are due to James Thomas (NYCRIS) for preparing and providing data from the National Cancer Data Repository and to Carolynn Gildea (Trent Cancer Registry) for the time and effort invested in helping with these analyses. This project was conceived and initially led by David Forman (IARC, formerly of NYCRIS) and supported by Catherine Thomson (Cancer Research UK) both of whose involvement has been invaluable. 9 NHS treated patients with a record of a major resection, by sex, age and deprivation quintile, 2004-2006, followed up to 2007 C15: Oesophagus Of all newly diagnosed cases of oesophageal cancer registered in England in 2004-2006 (excluding Death Certificate Only registrations), 97% were linked to at least one record within HES. The results presented on these pages show the percentage of these linked, non-DCO patients who had a record of a major resection as part of their treatment. Using OPCS-4 codes, operations that have been defined as major resections include oesophagectomy, and partial excisions of the oesophagus. The full list of OPCS4 codes used for oesophageal cancer are included in the appendix. These results are intending to show any differences in the percentage of NHS treated patients with a record of a major resection by different equality groups; age, sex and deprivation. However, caution should be taken when interpreting these results due to limitations in using HES data. These results do not show the proportion of patients who are cured of their cancer through surgery, although it is believed that the large majority of these operations will have been carried out with curative intent. In addition, the treatment of private patients will not be captured. Major resections by age and sex Male HES linked patients Age group % major resections 79 472 1,893 3,140 3,675 2,333 11,592 Under 40 40-49 50-59 60-69 70-79 80+ All ages 100% 28% 28% 28% 25% 15% 2% 18% Female 95% Confidence Interval 19% 24% 26% 23% 14% 1% 17% - HES linked patients 39% 32% 30% 26% 16% 2% 18% % major resections 27 165 606 1,154 1,942 2,353 6,247 33% 28% 27% 24% 11% 1% 12% Persons 95% Confidence Interval 19% 22% 23% 22% 9% 1% 11% - HES linked patients 52% 35% 30% 27% 12% 2% 12% % major resections 106 637 2,499 4,294 5,617 4,686 17,839 29% 28% 28% 25% 13% 1% 16% 95% Confidence Interval 21% 24% 26% 23% 12% 1% 15% - 39% 31% 30% 26% 14% 2% 16% Percentage of NHS treated patients with a record of a major resection for oesophageal cancer, by sex and age group 90% Percentage ge of patients 80% 70% 60% Male Female 50% 40% 30% 20% 10% 0% Under 40 40‐49 50‐59 Age group 60‐69 70‐79 80+ Major resections by deprivation quintile and sex Male HES linked patients Deprivation quintile 2,064 2,503 2,465 2,403 2,157 11,592 Quintile 1 - least deprived Quintile 2 Quintile 3 Quintile 4 Quintile 5 - most deprived All quintiles % major resections 21% 18% 17% 16% 15% 18% Female 95% Confidence Interval 19% 17% 16% 15% 14% 17% - HES linked patients 22% 20% 19% 18% 17% 18% % major resections 1,058 1,256 1,351 1,376 1,206 6,247 14% 12% 11% 10% 11% 12% Persons 95% Confidence Interval 12% 11% 10% 8% 10% 11% - HES linked patients 16% 14% 13% 11% 13% 12% % major resections 3,122 3,759 3,816 3,779 3,363 17,839 18% 16% 15% 14% 14% 16% 95% Confidence Interval 17% 15% 14% 13% 13% 15% - 20% 18% 16% 15% 15% 16% Quintile 100% Percentage of NHS treated patients with a record of a major resection for oesophageal cancer, by deprivation quintile 90% Percentage of patients 80% 70% 60% Male 50% Female 40% 30% 20% 10% 0% Least Deprived Quintile2 Quintile3 Quintile4 Most Deprived England Deprivation Quintile The percentage of patients with a record of a major resection is similar for males and females within each age band. However, there was a higher rate for males in the 70-79 age band compared to females. There is a decrease in the older age groups in the percentage of oesophageal cancer patients with a record of a major resection. In patients aged 60-69, 25% had a record of a major resection compared to 13% of 70-79 year olds and 1% of patients aged 80 and over. There was a decrease in the percentage of patients with a record of a major resection for males (-1.3% per quintile, p=0.002) by deprivation quintile that was statistically significant. There was no statistically significant change for females. The percentages by deprivation quintile have not been adjusted for differences in the age structure within each quintile quintile. 10 NHS treated patients with a record of a major resection, by sex and cancer network, 2004-2006 followed up to 2007 C15: Oesophagus The results on this page are a reflection of the surgical treatment data currently available through HES, however, there are limitations in the data available and therefore these results are being presented in order to stimulate further discussions with the clinical community as to what factors affect surgery rates and how we can improve data collection. Differences between cancer networks maybe due to higher rates of private patients, later stage of disease at diagnosis, co-morbidities, miscoding or poor data flow. It is important to read the introduction to this report to understand the limitations of data currently available nationally. These results are observational; there is no "good" or "bad" percentage from these results. Better quality data are required in order to understand how surgery rates can affect outcomes. The cancer network relates to the residence of the patient at diagnosis and not the hospital or trust where the patient was treated. Improved data quality and consistency of coding will allow further research into inequalities in cancer to be undertaken to create a better understanding of how patients are treated within the NHS and to target efforts to improve their outcomes. Major resections by cancer network and sex Male HES linked patients Cancer network 405 796 560 603 326 450 403 234 178 222 231 234 267 256 506 197 492 268 515 454 252 338 393 445 700 547 341 979 11,592 N01 Lancashire and South Cumbria CN N02 Greater Manchester and Cheshire CN N03 Merseyside and Cheshire CN N06 Yorkshire CN N07 Humber and Yorkshire Coast CN N08 North Trent CN N11 Pan Birmingham CN N12 Arden CN N20 Mount Vernon CN N21 West London CN N22 North London CN N23 North East London CN N24 South East London CN N25 South West London CN N26 Peninsula CN N27 Dorset CN N28 Avon, Somerset and Wiltshire CN N29 3 Counties CN N30 Thames Valley CN N31 Central South Coast CN N32 Surrey, West Sussex and Hampshire CN N33 Sussex CN N34 Kent and Medway CN N35 Greater Midlands CN N36 North of England CN N37 Anglia CN N38 Essex CN N39 East Midlands CN England % major resections 17% 16% 19% 20% 23% 23% 18% 21% 14% 14% 12% 12% 14% 11% 23% 13% 15% 16% 20% 13% 15% 6% 15% 21% 16% 18% 14% 25% 18% Female 95% Confidence Interval 13% 14% 16% 17% 18% 19% 15% 16% 10% 10% 9% 8% 11% 8% 19% 9% 13% 12% 17% 10% 11% 4% 11% 18% 13% 15% 11% 22% 17% - HES linked patients 21% 19% 23% 23% 28% 27% 22% 26% 20% 19% 17% 16% 19% 16% 26% 18% 19% 21% 24% 16% 20% 9% 18% 25% 19% 22% 18% 28% 18% 233 420 336 333 165 239 221 124 124 133 93 111 137 131 266 116 281 156 238 231 117 191 182 240 400 355 149 525 6,247 Percentage of NHS treated oesophageal cancer patients with a record of a major resection, by cancer network 30 11% 10% 18% 12% 17% 16% 17% 21% 11% 6% 5% 9% 6% 5% 11% 8% 7% 6% 14% 9% 7% 2% 7% 10% 11% 15% 10% 18% 12% Persons 95% Confidence Interval 7% 8% 15% 9% 12% 12% 13% 15% 7% 3% 2% 5% 3% 2% 7% 4% 5% 3% 10% 6% 4% 1% 4% 6% 8% 12% 6% 15% 11% - HES linked patients 15% 14% 23% 16% 23% 22% 23% 29% 18% 11% 12% 16% 11% 10% 15% 14% 11% 11% 19% 13% 13% 5% 11% 14% 14% 20% 16% 22% 12% 638 1,216 896 936 491 689 624 358 302 355 324 345 404 387 772 313 773 424 753 685 369 529 575 685 1,100 902 490 1,504 17,839 Age-Standardised Ratio 10 Networks below 99.8% Confidence limit: N22, N25, N31 & N33 1.6 12% 13% 17% 15% 17% 18% 15% 17% 10% 8% 7% 8% 9% 7% 16% 8% 10% 9% 16% 9% 9% 3% 10% 14% 12% 15% 10% 21% 15% - 18% 16% 22% 20% 25% 24% 21% 25% 17% 15% 14% 14% 15% 12% 21% 15% 15% 15% 21% 14% 16% 7% 15% 20% 16% 20% 16% 25% 16% 1.4 1.2 1.0 0.8 0.6 0.4 Networks below 99.8% Confidence limit: N25 & N33 0.2 0 15% 14% 19% 17% 21% 21% 18% 21% 13% 11% 10% 11% 11% 9% 18% 11% 12% 12% 18% 12% 12% 5% 12% 17% 14% 17% 13% 23% 16% Networks above 99.8% Confidence limit: N39 1.8 20 95% Confidence Interval % major resections Indirectly age-standardised ratio: actual number of NHS treated oesophageal cancer patients with a record of a major resection divided by the expected number, by cancer network 2.0 Networks above 99.8% Confidence limit: N08 & N39 Percentage of patients % major resections 0.0 0 200 400 600 800 1000 1200 1400 0 1600 Cancer network England average 50 100 150 200 250 Expected number of patients receiving a major resection Number of HES linked patients cancer network 99.8% confidence limits 99.8% confidence limit The funnel plot of percentages shows that six cancer networks fall outside the 99.8% confidence limits and therefore have a statistically significant difference from the average for England in the percentage of patients recorded as having a major resection. The funnel plot of age-standardised ratios shows that only three networks fall outside the 99.8% confidence limits. We cannot exclude the possibility that poor quality data flowing into HES may account for some of the differences seen. Note: It is important to examine the data for these networks more carefully and investigate further as to what factors other than age may underlie the apparent differences including coding quality within HES. The percentages shown in the table above do not take into account any factors such as differences in the age-distributions, co-morbidities or stage at diagnosis of patients between cancer networks. 11 NHS treated patients with a record of a major resection, by sex, age and deprivation quintile, 2004-2006, followed up to 2007 C16: Stomach Of all newly diagnosed cases of stomach cancer registered in England in 2004-2006 (excluding Death Certificate Only registrations), 95% were linked to at least one record within HES. The results presented on these pages show the percentage of these linked, non-DCO patients who had a record of a major resection as part of their treatment. Using OPCS-4 codes, operations that have been defined as major resections include total excision of stomach and partial excision of the stomach. The full list of OPCS-4 codes used for stomach cancer are included in the appendix. These results are intending to show any differences in the percentage of NHS treated patients with a record of a major resection by different equality groups; age, sex and deprivation. However, caution should be taken when interpreting these results due to limitations in using HES data. These results do not show the proportion of patients who are cured of their cancer through surgery, although it is believed that the large majority of these operations will have been carried out with curative intent. In addition, the treatment of private patients will not be captured. Major resections by age and sex Male HES linked patients Age group % major resections 120 398 1,204 2,681 4,380 2,941 11,724 Under 40 40-49 50-59 60-69 70-79 80+ All ages 100% 18% 16% 16% 18% 17% 9% 15% Female 95% Confidence Interval 12% 13% 14% 17% 16% 8% 14% - HES linked patients 25% 20% 18% 20% 18% 10% 16% % major resections 119 223 431 1,076 1,878 2,379 6,106 24% 21% 19% 19% 20% 7% 15% Persons 95% Confidence Interval 17% 16% 16% 17% 18% 6% 14% - HES linked patients 32% 27% 23% 21% 21% 8% 15% % major resections 239 621 1,635 3,757 6,258 5,320 17,830 21% 18% 17% 18% 18% 8% 15% 95% Confidence Interval 16% 15% 15% 17% 17% 7% 14% - 26% 21% 19% 19% 19% 9% 15% Percentage of NHS treated patients with a record of a major resection for stomach cancer, by sex and age group 90% Percentage ge of patients 80% 70% 60% Male Female 50% 40% 30% 20% 10% 0% Under 40 40‐49 50‐59 Age group 60‐69 70‐79 80+ Major resections by deprivation quintile and sex Male HES linked patients Deprivation quintile 1,891 2,259 2,411 2,592 2,571 11,724 Quintile 1 - least deprived Quintile 2 Quintile 3 Quintile 4 Quintile 5 - most deprived All quintiles % major resections 15% 15% 14% 15% 16% 15% Female 95% Confidence Interval 14% 14% 12% 14% 14% 14% - HES linked patients 17% 17% 15% 17% 17% 16% % major resections 863 1,143 1,308 1,382 1,410 6,106 17% 13% 15% 14% 14% 15% Persons 95% Confidence Interval 15% 11% 13% 13% 13% 14% - HES linked patients 20% 15% 17% 16% 16% 15% % major resections 2,754 3,402 3,719 3,974 3,981 17,830 16% 15% 14% 15% 15% 15% 95% Confidence Interval 15% 13% 13% 14% 14% 14% - 17% 16% 15% 16% 16% 15% Quintile 100% Percentage of NHS treated patients with a record of a major resection for stomach cancer, by deprivation quintile 90% Percentage of patients 80% 70% 60% Male 50% Female 40% 30% 20% 10% 0% Least Deprived Quintile2 Quintile3 Quintile4 Most Deprived England Deprivation Quintile The difference in the percentage of patients with a record of a major resection between males and females within each age band is not statistically significant. In patients aged under 80, around 18% had a record of a major resection. Across age bands for these patients, the difference in the percentage of patients with a record of a major resection was not statistically significant. The rate dropped for patients aged 80 and over to 8%. Across deprivation quintiles, there was no statistically significant change in the percentage of patients with a record of a major resection for either males or females. The percentages by deprivation quintile have not been adjusted for differences in the age structure in each quintile. 12 NHS treated patients with a record of a major resection, by sex and cancer network, 2004-2006 followed up to 2007 C16: Stomach The results on this page are a reflection of the surgical treatment data currently available through HES, however, there are limitations in the data available and therefore these results are being presented in order to stimulate further discussions with the clinical community as to what factors affect surgery rates and how we can improve data collection. Differences between cancer networks maybe due to higher rates of private patients, later stage of disease at diagnosis, co-morbidities, miscoding or poor data flow. It is important to read the introduction to this report to understand the limitations of data currently available nationally. These results are observational; there is no "good" or "bad" percentage from these results. Better quality data are required in order to understand how surgery rates can affect outcomes. The cancer network relates to the residence of the patient at diagnosis and not the hospital or trust where the patient was treated. Improved data quality and consistency of coding will allow further research into inequalities in cancer to be undertaken to create a better understanding of how patients are treated within the NHS and to target efforts to improve their outcomes. Major resections by cancer network and sex Male HES linked patients Cancer network N01 Lancashire and South Cumbria CN N02 Greater Manchester and Cheshire CN N03 Merseyside and Cheshire CN N06 Yorkshire CN N07 Humber and Yorkshire Coast CN N08 North Trent CN N11 Pan Birmingham CN N12 Arden CN N20 Mount Vernon CN N21 West London CN N22 North London CN N23 North East London CN N24 South East London CN N25 South West London CN N26 Peninsula CN N27 Dorset CN N28 Avon, Somerset and Wiltshire CN N29 3 Counties CN N30 Thames Valley CN N31 Central South Coast CN N32 Surrey, West Sussex and Hampshire CN N33 Sussex CN N34 Kent and Medway CN N35 Greater Midlands CN N36 North of England CN N37 Anglia CN N38 Essex CN N39 East Midlands CN England % major resections 344 845 600 599 299 581 511 215 204 251 197 298 272 254 401 190 365 214 376 409 184 211 338 566 979 736 285 1,000 11,724 14% 16% 16% 19% 17% 20% 10% 12% 20% 18% 17% 16% 10% 6% 12% 6% 11% 25% 11% 12% 11% 9% 15% 14% 19% 13% 11% 20% 15% Female 95% Confidence Interval 11% 14% 13% 16% 13% 17% 7% 8% 15% 14% 12% 12% 7% 3% 9% 4% 8% 19% 9% 9% 7% 6% 12% 11% 17% 11% 8% 17% 14% - HES linked patients 18% 19% 19% 22% 22% 23% 12% 17% 26% 23% 23% 20% 14% 9% 15% 11% 15% 31% 15% 15% 16% 14% 20% 17% 22% 16% 15% 22% 16% 190 465 309 360 165 319 247 110 113 140 150 162 148 126 201 94 226 103 174 177 109 117 163 280 568 290 148 452 6,106 Percentage of NHS treated stomach cancer patients with a record of a major resection, by cancer network 30 21% 18% 15% 16% 14% 17% 10% 8% 19% 19% 12% 12% 10% 11% 11% 5% 10% 17% 10% 13% 12% 14% 12% 13% 17% 16% 15% 17% 15% Persons 95% Confidence Interval 15% 15% 11% 12% 9% 13% 7% 4% 13% 13% 8% 8% 6% 7% 7% 2% 7% 11% 7% 9% 7% 9% 8% 9% 14% 12% 10% 14% 14% - HES linked patients 27% 22% 19% 20% 20% 22% 14% 15% 28% 26% 18% 18% 16% 18% 16% 12% 15% 26% 16% 19% 19% 21% 18% 17% 21% 21% 21% 21% 15% 534 1,310 909 959 464 900 758 325 317 391 347 460 420 380 602 284 591 317 550 586 293 328 501 846 1,547 1,026 433 1,452 17,830 Age-Standardised Ratio 10 Networks below 99.8% Confidence limit: N11, N24, N25, N27 & N28 16% 17% 15% 18% 16% 19% 10% 10% 20% 18% 15% 15% 10% 7% 11% 6% 11% 22% 11% 12% 11% 11% 14% 13% 18% 14% 12% 19% 15% 14% 15% 13% 15% 13% 16% 8% 8% 16% 15% 11% 12% 7% 5% 9% 4% 9% 18% 9% 10% 8% 8% 12% 11% 17% 12% 9% 17% 14% - 20% 19% 18% 20% 20% 22% 12% 14% 24% 22% 19% 18% 13% 10% 14% 9% 14% 27% 14% 15% 15% 15% 18% 16% 20% 16% 16% 21% 15% Networks above 99.8% Confidence limit: N36 & N39 1.8 20 95% Confidence Interval % major resections Indirectly age-standardised ratio: actual number of NHS treated stomach cancer patients with a record of a major resection divided by the expected number, by cancer network 2.0 Networks above 99.8% Confidence limit: N29, N36 & N39 Percentage of patients % major resections 1.6 1.4 1.2 1.0 0.8 0.6 Networks below 99.8% Confidence limit: N11, N25 & N27 0.4 0.2 0.0 0 0 200 400 600 800 1000 1200 1400 0 1600 England average 100 150 200 250 Expected number of patients receiving a major resection Number of HES linked patients Cancer network 50 cancer network 99.8% confidence limits 99.8% confidence limit The funnel plot of percentages shows that eight cancer networks fall outside the 99.8% confidence limits and therefore have a statistically significant difference from the average for England in the percentage of patients recorded with a major resection. The funnel plot of age-standardised ratios between observed and expected number of patients with a record of a major resection only shows that five cancer networks fall outside the 99.8% confidence limits. We cannot exclude the possibility that poor quality data flowing into HES may also account for some of the differences seen. Note: It is important to examine the data for these networks more carefully and investigate further as to what other factors may underlie the apparent differences including coding quality within HES. The percentages shown in the table above do not take into account any factors such as differences in the age-distributions, comorbidities or stage at diagnosis of patients between cancer networks. 13 NHS treated patients with a record of a major resection, by sex, age and deprivation quintile, 2004-2006, followed up to 2007 C22: Liver Of all newly diagnosed cases of liver cancer registered in England in 2004-2006 (excluding Death Certificate Only registrations), 90% were linked to at least one record within HES. The results presented on these pages show the percentage of these linked, non-DCO patients who had a record of a major resection as part of their treatment. Using OPCS-4 codes, operations that have been defined as major resections are those classified under partial excisions of the liver. The full list of OPCS-4 codes used for liver cancer are included in the appendix. These results are intending to show any differences in the percentage of NHS treated patients with a record of a major resection by different equality groups; age, sex and deprivation. However, caution should be taken when interpreting these results due to limitations in using HES data. These results do not show the proportion of patients who are cured of their cancer through surgery, although it is believed that the large majority of these operations will have been carried out with curative intent. In addition, the treatment of private patients will not be captured. Major resections by age and sex Male HES linked patients Age group % major resections 108 190 544 951 1,256 707 3,756 Under 40 40-49 50-59 60-69 70-79 80+ All ages 100% 26% 6% 8% 7% 4% 1% 6% Female 95% Confidence Interval 19% 4% 6% 5% 3% 1% 5% - HES linked patients 35% 11% 11% 9% 5% 2% 6% % major resections 69 97 251 459 697 727 2,300 32% 20% 12% 9% 5% 1% 7% Persons 95% Confidence Interval 22% 13% 9% 7% 3% 0% 6% - HES linked patients 44% 29% 17% 12% 6% 2% 8% % major resections 177 287 795 1,410 1,953 1,434 6,056 28% 11% 10% 8% 4% 1% 6% 95% Confidence Interval 22% 8% 8% 6% 3% 1% 5% - 35% 15% 12% 9% 5% 2% 7% Percentage of NHS treated patients with a record of a major resection for liver cancer, by sex and age group 90% Percentage ge of patients 80% 70% 60% Male Female 50% 40% 30% 20% 10% 0% Under 40 40‐49 50‐59 Age group 60‐69 70‐79 80+ Major resections by deprivation quintile and sex Male HES linked patients Deprivation quintile 654 703 736 777 886 3,756 Quintile 1 - least deprived Quintile 2 Quintile 3 Quintile 4 Quintile 5 - most deprived All quintiles % major resections 8% 5% 6% 5% 5% 6% Female 95% Confidence Interval 6% 3% 4% 4% 4% 5% - HES linked patients 10% 7% 7% 7% 6% 6% % major resections 378 420 492 501 509 2,300 8% 8% 6% 6% 5% 7% Persons 95% Confidence Interval 6% 5% 4% 4% 4% 6% - HES linked patients 11% 11% 9% 9% 8% 8% % major resections 1,032 1,123 1,228 1,278 1,395 6,056 8% 6% 6% 6% 5% 6% 95% Confidence Interval 6% 5% 5% 5% 4% 5% - 10% 7% 7% 7% 6% 7% Quintile 100% Percentage of NHS treated patients with a record of a major resection for liver cancer, by deprivation quintile 90% Percentage of patients 80% 70% 60% Male 50% Female 40% 30% 20% 10% 0% Least Deprived Quintile2 Quintile3 Quintile4 Most Deprived England Deprivation Quintile The percentage of patients aged 50 and over with a record of a major resection is similar for males and females within each age band. However, there was a higher rate for females in the 40-49 age band compared to males. There is a decrease in the older age groups in the percentage of liver cancer patients with a record of a major resection. In patients aged 60-69, 8% have a record of a major resection compared to 4% of 70-79 year olds and 1% of patients aged 80 and over. Across deprivation quintiles, there was no statistically significant change in the percentage of patients with a record of a major resection for males, however for females, there was a decrease which was statistically significant (-0.71% per quintile, p=0.011). The percentages by deprivation quintile have not been adjusted for differences in the age structure. structure 14 NHS treated patients with a record of a major resection, by sex and cancer network, 2004-2006 followed up to 2007 C22: Liver The results on this page are a reflection of the surgical treatment data currently available through HES, however, there are limitations in the data available and therefore these results are being presented in order to stimulate further discussions with the clinical community as to what factors affect surgery rates and how we can improve data collection. Differences between cancer networks maybe due to higher rates of private patients, later stage of disease at diagnosis, co-morbidities, miscoding or poor data flow. It is important to read the introduction to this report to understand the limitations of data currently available nationally. These results are observational; there is no "good" or "bad" percentage from these results. Better quality data are required in order to understand how surgery rates can affect outcomes. The cancer network relates to the residence of the patient at diagnosis and not the hospital or trust where the patient was treated. Improved data quality and consistency of coding will allow further research into inequalities in cancer to be undertaken to create a better understanding of how patients are treated within the NHS and to target efforts to improve their outcomes. Major resections by cancer network and sex Male HES linked patients Cancer network N01 Lancashire and South Cumbria CN N02 Greater Manchester and Cheshire CN N03 Merseyside and Cheshire CN N06 Yorkshire CN N07 Humber and Yorkshire Coast CN N08 North Trent CN N11 Pan Birmingham CN N12 Arden CN N20 Mount Vernon CN N21 West London CN N22 North London CN N23 North East London CN N24 South East London CN N25 South West London CN N26 Peninsula CN N27 Dorset CN N28 Avon, Somerset and Wiltshire CN N29 3 Counties CN N30 Thames Valley CN N31 Central South Coast CN N32 Surrey, West Sussex and Hampshire CN N33 Sussex CN N34 Kent and Medway CN N35 Greater Midlands CN N36 North of England CN N37 Anglia CN N38 Essex CN N39 East Midlands CN England % major resections 132 297 172 225 68 145 110 34 67 134 110 117 119 96 157 93 144 67 135 162 68 85 82 105 280 189 76 287 3,756 6% 5% 4% 11% 4% 8% 6% 9% 4% 9% 5% 3% 2% 5% 3% 3% 4% 1% 4% 5% 6% 4% 5% 4% 4% 6% 5% 9% 6% Female 95% Confidence Interval 3% 3% 2% 8% 2% 5% 3% 3% 2% 5% 3% 1% 0% 2% 1% 1% 2% 0% 2% 3% 2% 1% 2% 1% 2% 4% 2% 6% 5% - HES linked patients 12% 9% 8% 16% 12% 14% 13% 23% 12% 15% 11% 8% 6% 12% 7% 9% 9% 8% 9% 9% 14% 10% 12% 9% 7% 11% 13% 13% 6% 90 208 118 136 68 94 60 31 39 66 61 74 47 51 77 49 104 40 81 84 44 58 51 66 170 99 46 188 2,300 Percentage of NHS treated liver cancer patients with a record of a major resection, by cancer network 14 Age-Standardised Ratio 10 Percentage of patients (numbers shown are %) 6% 5% 6% 7% 6% 3% 7% 6% 3% 3% 7% 0% 9% 6% 8% 10% 6% 15% 4% 12% 14% 5% 6% 8% 6% 7% 9% 10% 7% 8 6 Persons 95% Confidence Interval 2% 3% 3% 4% 2% 1% 3% 2% 0% 1% 3% 0% 3% 2% 4% 4% 3% 7% 1% 7% 6% 2% 2% 3% 3% 3% 3% 6% 6% - HES linked patients 12% 9% 12% 12% 14% 9% 16% 21% 13% 10% 16% 5% 20% 16% 16% 22% 12% 29% 10% 21% 27% 14% 16% 17% 10% 14% 20% 15% 8% 222 505 290 361 136 239 170 65 106 200 171 191 166 147 234 142 248 107 216 246 112 143 133 171 450 288 122 475 6,056 % major resections 6% 5% 5% 9% 5% 6% 6% 8% 4% 7% 6% 2% 4% 5% 5% 6% 5% 7% 4% 7% 9% 4% 5% 5% 5% 7% 7% 9% 6% 95% Confidence Interval 3% 4% 3% 7% 3% 4% 4% 3% 1% 4% 3% 1% 2% 3% 3% 3% 3% 3% 2% 5% 5% 2% 3% 3% 3% 4% 3% 7% 5% - 10% 8% 8% 13% 10% 10% 11% 17% 9% 11% 10% 5% 8% 10% 8% 11% 8% 13% 8% 11% 16% 9% 10% 10% 7% 10% 12% 12% 7% Indirectly age-standardised ratio: actual number of NHS treated liver cancer patients with a record of a major resection divided by the expected number, by cancer network 2.5 Networks above 99.8% Confidence limit: None 12 % major resections Networks above 99.8% Confidence limit: None 2.0 1.5 1.0 4 0.5 Networks below 99.8% Confidence limit: N23 2 Networks below 99.8% Confidence limit: None 0 0.0 0 100 200 300 400 0 500 England average 10 15 20 25 30 35 Expected number of patients receiving a major resection Number of HES linked patients Cancer network 5 cancer network 99.8% confidence limits 99.8% confidence limit The funnel plot of percentages show that the majority of cancer networks fall within the 99.8% confidence limits and therefore do not have a statistically significant difference from the average for England in the percentage of patients recorded as having a major resection. The funnel plot of age-standardised ratios shows that all cancer networks fall between the 99.8% confidence limits. Note: The percentages shown in the table above do not take into account any factors such as differences in the age-distributions, co-morbidities or stage at diagnosis of patients between cancer networks. 15 NHS treated patients with a record of a major resection, by sex, age and deprivation quintile, 2004-2006, followed up to 2007 C25: Pancreas Of all newly diagnosed cases of pancreatic cancer registered in England in 2004-2006 (excluding Death Certificate Only registrations), 92% were linked to at least one record within HES. The results presented on these pages show the percentage of these linked, non-DCO patients who had a record of a major resection as part of their treatment. Using OPCS-4 codes, operations that have been defined as major resections include total excision of the pancreas, excision of head of pancreas and partial excision of the pancreas. The full list of OPCS-4 codes used for pancreatic cancer are included in the appendix. These results are intending to show any differences in the percentage of NHS treated patients with a record of a major resection by different equality groups; age, sex and deprivation. However, caution should be taken when interpreting these results due to limitations in using HES data. These results do not show the proportion of patients who are cured of their cancer through surgery, although it is believed that the large majority of these operations will have been carried out with curative intent. In addition, the treatment of private patients will not be captured. Major resections by age and sex Male HES linked patients Age group % major resections 70 295 1,149 2,131 2,613 1,660 7,918 Under 40 40-49 50-59 60-69 70-79 80+ All ages 100% 14% 14% 13% 13% 8% 1% 9% Female 95% Confidence Interval 8% 10% 11% 11% 7% 1% 8% - HES linked patients 24% 18% 15% 14% 9% 1% 9% % major resections 71 227 890 1,781 2,555 2,632 8,156 32% 24% 14% 12% 7% 1% 7% Persons 95% Confidence Interval 23% 19% 12% 10% 6% 0% 7% - HES linked patients 44% 30% 17% 13% 8% 1% 8% % major resections 141 522 2,039 3,912 5,168 4,292 16,074 23% 18% 13% 12% 7% 1% 8% 95% Confidence Interval 17% 15% 12% 11% 7% 1% 8% - 31% 22% 15% 13% 8% 1% 8% Percentage of NHS treated patients with a record of a major resection for pancreatic cancer, by sex and age group 90% Percentage ge of patients 80% 70% 60% Male Female 50% 40% 30% 20% 10% 0% Under 40 40‐49 50‐59 Age group 60‐69 70‐79 80+ Major resections by deprivation quintile and sex Male HES linked patients Deprivation quintile 1,562 1,747 1,691 1,580 1,338 7,918 Quintile 1 - least deprived Quintile 2 Quintile 3 Quintile 4 Quintile 5 - most deprived All quintiles % major resections 9% 9% 8% 8% 8% 9% Female 95% Confidence Interval 8% 8% 7% 7% 7% 8% - HES linked patients 11% 11% 10% 9% 10% 9% % major resections 1,465 1,757 1,745 1,732 1,457 8,156 8% 8% 6% 7% 7% 7% Persons 95% Confidence Interval 7% 7% 5% 6% 6% 7% - HES linked patients 10% 10% 8% 8% 8% 8% % major resections 3,027 3,504 3,436 3,312 2,795 16,074 9% 9% 7% 7% 7% 8% 95% Confidence Interval 8% 8% 7% 6% 6% 8% - 10% 10% 8% 8% 8% 8% Quintile 100% Percentage of NHS treated patients with a record of a major resection for pancreatic cancer, by deprivation quintile 90% Percentage of patients 80% 70% 60% Male 50% Female 40% 30% 20% 10% 0% Least Deprived Quintile2 Quintile3 Quintile4 Most Deprived England Deprivation Quintile The difference in the percentage of patients with a record of a major resection between males and females within each age band is not statistically significant above the age of 50. There is a decrease in the older age groups in the percentage of pancreatic cancer patients with a record of a major resection. In patients aged 60-69, 12% had a record of a major resection compared to 7% of 70-79 year olds and 1% of patients aged 80 and over. There was a decrease in the percentage of patients with a record of a major resection for males (-0.5% per quintile, p=0.04) by deprivation quintile that was statistically significant. There was no statistically significant change for females. The percentages by deprivation quintile have not been adjusted for differences in the age structure. 16 NHS treated patients with a record of a major resection, by sex and cancer network, 2004-2006 followed up to 2007 C25: Pancreas The results on this page are a reflection of the surgical treatment data currently available through HES, however, there are limitations in the data available and therefore these results are being presented in order to stimulate further discussions with the clinical community as to what factors affect surgery rates and how we can improve data collection. Differences between cancer networks maybe due to higher rates of private patients, later stage of disease at diagnosis, co-morbidities, miscoding or poor data flow. It is important to read the introduction to this report to understand the limitations of data currently available nationally. These results are observational; there is no "good" or "bad" percentage from these results. Better quality data are required in order to understand how surgery rates can affect outcomes. The cancer network relates to the residence of the patient at diagnosis and not the hospital or trust where the patient was treated. Improved data quality and consistency of coding will allow further research into inequalities in cancer to be undertaken to create a better understanding of how patients are treated within the NHS and to target efforts to improve their outcomes. Major resections by cancer network and sex Male HES linked patients Cancer network 250 431 310 394 180 311 206 102 157 194 180 219 206 217 332 145 300 188 346 328 177 196 259 255 547 506 239 743 7,918 N01 Lancashire and South Cumbria CN N02 Greater Manchester and Cheshire CN N03 Merseyside and Cheshire CN N06 Yorkshire CN N07 Humber and Yorkshire Coast CN N08 North Trent CN N11 Pan Birmingham CN N12 Arden CN N20 Mount Vernon CN N21 West London CN N22 North London CN N23 North East London CN N24 South East London CN N25 South West London CN N26 Peninsula CN N27 Dorset CN N28 Avon, Somerset and Wiltshire CN N29 3 Counties CN N30 Thames Valley CN N31 Central South Coast CN N32 Surrey, West Sussex and Hampshire CN N33 Sussex CN N34 Kent and Medway CN N35 Greater Midlands CN N36 North of England CN N37 Anglia CN N38 Essex CN N39 East Midlands CN England % major resections 10% 8% 10% 10% 9% 7% 18% 10% 7% 12% 7% 4% 13% 7% 7% 3% 4% 9% 9% 12% 8% 5% 8% 10% 11% 8% 5% 8% 9% Female 95% Confidence Interval 7% 6% 7% 7% 6% 4% 13% 5% 4% 8% 4% 2% 9% 4% 5% 1% 3% 5% 6% 9% 5% 2% 5% 7% 9% 6% 3% 6% 8% - HES linked patients 14% 11% 13% 13% 14% 10% 24% 17% 12% 18% 12% 8% 18% 11% 11% 8% 7% 13% 12% 16% 14% 8% 12% 14% 14% 11% 8% 10% 9% 255 479 354 388 193 326 216 106 138 181 198 224 197 215 346 182 356 181 330 400 187 223 251 215 588 520 239 668 8,156 Percentage of NHS treated pancreatic cancer patients with a record of a major resection, by cancer network 20 5% 6% 5% 5% 3% 6% 11% 10% 2% 5% 6% 3% 5% 3% 3% 2% 4% 3% 5% 8% 5% 2% 3% 7% 5% 5% 4% 6% 7% - HES linked patients 12% 11% 11% 10% 10% 12% 21% 24% 8% 13% 14% 9% 12% 10% 8% 8% 9% 10% 11% 14% 12% 7% 8% 15% 10% 9% 10% 10% 8% 505 910 664 782 373 637 422 208 295 375 378 443 403 432 678 327 656 369 676 728 364 419 510 470 1,135 1,026 478 1,411 16,074 10 Networks below 99.8% Confidence limit: N23, N27, N28 & N33 95% Confidence Interval 9% 8% 8% 9% 7% 8% 17% 13% 5% 10% 8% 5% 10% 6% 6% 4% 5% 7% 8% 11% 8% 4% 6% 10% 9% 7% 5% 8% 8% 7% 7% 7% 7% 5% 6% 13% 9% 3% 7% 6% 3% 8% 4% 5% 2% 4% 5% 6% 9% 6% 3% 4% 8% 8% 6% 4% 7% 8% - 12% 10% 11% 11% 10% 10% 20% 18% 9% 14% 11% 7% 14% 9% 8% 6% 7% 10% 11% 14% 11% 6% 9% 13% 11% 9% 8% 10% 8% Networks above 99.8% Confidence limit: N11 2.0 1.5 1.0 Networks below 99.8% Confidence limit: N27 & N33 0.5 0 % major resections Indirectly age-standardised ratio: actual number of NHS treated pancreatic cancer patients with a record of a major resection divided by the expected number, by cancer network 2.5 Age-Standardised Ratio Percentage of patients 8% 8% 7% 7% 6% 8% 15% 16% 4% 8% 9% 5% 8% 6% 5% 4% 6% 6% 8% 11% 7% 4% 5% 10% 7% 7% 6% 8% 7% 3.0 Networks above 99.8% Confidence limit: N11 Persons 95% Confidence Interval % major resections 0.0 0 200 400 600 800 1000 1200 0 1400 Cancer network England average 20 40 60 80 100 120 Expected number of patients receiving a major resection Number of HES linked patients 99.8% confidence limits cancer network 99.8% confidence limit The funnel plot of cancer network percentages shows that the majority of cancer networks fall within the 99.8% confidence limits and therefore do not have a statistically significant difference from the average for England in the percentage of patients recorded as having a major resection. However, the percentages for five cancer networks do fall outside the confidence limits. The funnel plot of age-standardised ratios between observed and expected number of patients with a record of a major resection shows that three cancer networks fall outside the 99.8% confidence limits. We cannot exclude the possibility that poor quality data flowing into HES may account for some of the differences seen. Note: It is important to examine the data for these networks more carefully and investigate further as to what other factors may underlie the apparent differences including coding quality within HES. The percentages shown in the table above do not take into account any factors such as differences in the age-distributions, comorbidities or stage at diagnosis of patients between cancer networks. 17 NHS treated patients with a record of a major resection, by sex, age and deprivation quintile, 2004-2006, followed up to 2007 C18-20: Colorectal Of all newly diagnosed cases of colorectal cancer registered in England in 2004-2006 (excluding Death Certificate Only registrations), 94% were linked to at least one record within HES. The results presented on these pages show the percentage of these linked, non-DCO patients who had a record of a major resection as part of their treatment. Using OPCS-4 codes, operations such as hemicoloectomy, total colectomy and total excision of colon were included as major resections. The full list of OPCS-4 codes used for colorectal cancer are included in the appendix. These results are intending to show any differences in the percentage of NHS treated patients with a record of a major resection by different equality groups; age, sex and deprivation. However, caution should be taken when interpreting these results due to limitations in using HES data. These results do not show the proportion of patients who are cured of their cancer through surgery, although it is believed that the large majority of these operations will have been carried out with curative intent. In addition, the treatment of private patients will not be captured. Major resections by age and sex Male HES linked patients Age group % major resections 565 1,640 5,684 11,572 15,772 9,630 44,863 Under 40 40-49 50-59 60-69 70-79 80+ All ages 100% 68% 65% 68% 70% 69% 56% 66% Female 95% Confidence Interval 64% 63% 67% 69% 68% 55% 66% - HES linked patients 72% 68% 69% 71% 70% 57% 67% % major resections 514 1,407 3,933 7,250 11,505 11,218 35,827 69% 71% 73% 74% 71% 55% 67% Persons 95% Confidence Interval 65% 68% 72% 73% 70% 54% 66% - HES linked patients 73% 73% 74% 75% 72% 56% 67% % major resections 1,079 3,047 9,617 18,822 27,277 20,848 80,690 68% 68% 70% 71% 70% 55% 66% 95% Confidence Interval 66% 66% 69% 71% 69% 55% 66% - 71% 69% 71% 72% 70% 56% 67% Percentage of NHS treated patients with a record of a major resection for colorectal cancer, by sex and age group 90% Percentage ge of patients 80% 70% 60% Male Female 50% 40% 30% 20% 10% 0% Under 40 40‐49 50‐59 Age group 60‐69 70‐79 80+ Major resections by deprivation quintile and sex Male HES linked patients Deprivation quintile 9,082 9,829 9,512 8,778 7,662 44,863 Quintile 1 - least deprived Quintile 2 Quintile 3 Quintile 4 Quintile 5 - most deprived All quintiles % major resections 68% 68% 66% 65% 64% 66% Female 95% Confidence Interval 67% 67% 65% 64% 63% 66% - HES linked patients 69% 69% 67% 66% 65% 67% % major resections 6,925 7,809 7,801 7,360 5,932 35,827 68% 67% 67% 66% 64% 67% Persons 95% Confidence Interval 67% 66% 66% 65% 63% 66% - HES linked patients 69% 68% 68% 67% 65% 67% % major resections 16,007 17,638 17,313 16,138 13,594 80,690 68% 68% 67% 66% 64% 66% 95% Confidence Interval 67% 67% 66% 65% 63% 66% - 69% 68% 67% 66% 65% 67% Quintile 100% Percentage of NHS treated patients with a record of a major resection for colorectal cancer, by deprivation quintile 90% Percentage of patients 80% 70% 60% Male 50% Female 40% 30% 20% 10% 0% Least Deprived Quintile2 Quintile3 Quintile4 Most Deprived England Deprivation Quintile The percentage of patients with a record of a major resection is higher for females compared to males for patients in each ten year age group between 40 and 79. However, there was no difference in the percentage for patients aged 80 and over. The percentage receiving a major resection is similar for all age groups. However, for patients aged 80 and over, the percentage falls to 55%, compared to around 70% for all other age groups. Across the deprivation quintiles, there was a decrease in the percentage of patients with a record of a major resection for both males (-1.1% per quintile, p=0.02) and females (-1.0% per quintile, p=0.029) by deprivation quintile that was statistically significant . The percentages by deprivation quintile have not been adjusted for differences in the age structure structure. 18 NHS treated patients with a record of a major resection, by sex and cancer network, 2004-2006 followed up to 2007 C18-20: Colorectal The results on this page are a reflection of the surgical treatment data currently available through HES, however, there are limitations in the data available and therefore these results are being presented in order to stimulate further discussions with the clinical community as to what factors affect surgery rates and how we can improve data collection. Differences between cancer networks maybe due to higher rates of private patients, later stage of disease at diagnosis, co-morbidities, miscoding or poor data flow. It is important to read the introduction to this report to understand the limitations of data currently available nationally. These results are observational; there is no "good" or "bad" percentage from these results. Better quality data are required in order to understand how surgery rates can affect outcomes. The cancer network relates to the residence of the patient at diagnosis and not the hospital or trust where the patient was treated. Improved data quality and consistency of coding will allow further research into inequalities in cancer to be undertaken to create a better understanding of how patients are treated within the NHS and to target efforts to improve their outcomes. Major resections by cancer network and sex Male HES linked patients Cancer network 1,476 2,748 1,958 2,293 1,099 1,765 1,613 836 853 935 919 848 950 1,052 1,880 834 1,851 1,111 1,857 1,858 870 1,027 1,323 1,828 3,342 2,728 1,214 3,795 44,863 N01 Lancashire and South Cumbria CN N02 Greater Manchester and Cheshire CN N03 Merseyside and Cheshire CN N06 Yorkshire CN N07 Humber and Yorkshire Coast CN N08 North Trent CN N11 Pan Birmingham CN N12 Arden CN N20 Mount Vernon CN N21 West London CN N22 North London CN N23 North East London CN N24 South East London CN N25 South West London CN N26 Peninsula CN N27 Dorset CN N28 Avon, Somerset and Wiltshire CN N29 3 Counties CN N30 Thames Valley CN N31 Central South Coast CN N32 Surrey, West Sussex and Hampshire CN N33 Sussex CN N34 Kent and Medway CN N35 Greater Midlands CN N36 North of England CN N37 Anglia CN N38 Essex CN N39 East Midlands CN England 66% 67% 69% 66% 70% 63% 70% 68% 63% 65% 64% 59% 59% 60% 67% 61% 66% 73% 63% 68% 65% 63% 60% 71% 67% 71% 67% 65% 66% Female 95% Confidence Interval 64% 65% 67% 65% 67% 61% 68% 65% 60% 62% 61% 56% 56% 57% 65% 58% 64% 70% 61% 66% 62% 60% 58% 69% 66% 69% 64% 63% 66% - HES linked patients 68% 69% 71% 68% 73% 65% 72% 71% 66% 68% 67% 62% 62% 63% 69% 64% 69% 75% 65% 70% 68% 66% 63% 73% 69% 72% 69% 66% 67% Persons 95% Confidence Interval 59% 64% 65% 65% 64% 61% 70% 70% 63% 64% 62% 56% 54% 56% 67% 64% 63% 71% 62% 64% 61% 61% 60% 70% 65% 70% 64% 64% 66% - HES linked patients 65% 68% 70% 69% 70% 66% 75% 77% 70% 70% 69% 63% 61% 62% 72% 70% 68% 77% 67% 69% 68% 67% 66% 75% 69% 74% 69% 67% 67% 2,611 4,814 3,324 4,095 1,974 3,106 2,754 1,452 1,573 1,767 1,649 1,574 1,725 2,030 3,435 1,602 3,401 1,972 3,329 3,488 1,670 2,046 2,426 3,196 5,846 4,942 2,248 6,641 80,690 Age-Standardised Ratio 65 60 Networks below 99.8% Confidence limit: N08, N23, N24, N25 & N34 64% 66% 69% 67% 69% 63% 71% 70% 65% 66% 65% 59% 58% 59% 68% 64% 66% 73% 64% 67% 65% 64% 61% 72% 67% 71% 67% 65% 66% 62% 65% 67% 65% 67% 61% 70% 68% 62% 64% 62% 57% 56% 57% 67% 61% 64% 71% 62% 66% 63% 61% 60% 70% 66% 70% 65% 64% 66% - 66% 68% 70% 68% 71% 65% 73% 73% 67% 68% 67% 62% 61% 61% 70% 66% 67% 75% 65% 69% 67% 66% 63% 73% 68% 72% 69% 66% 67% Networks above 99.8% Confidence limit: N29, N35 & N37 1.1 1.0 0.9 Networks below 99.8% Confidence limit: N23, N24, N25 & N34 0.8 50 95% Confidence Interval % major resections Indirectly age-standardised ratio: actual number of NHS treated colorectal cancer patients with a record of a major resection divided by the expected number, by cancer network 1.2 70 55 62% 66% 67% 67% 67% 64% 73% 74% 66% 67% 66% 59% 58% 59% 70% 67% 65% 74% 65% 67% 65% 64% 63% 72% 67% 72% 67% 66% 67% 1.3 Networks above 99.8% Confidence limit: N11, N12, N29, N35 & N37 75 % major resections 1,135 2,066 1,366 1,802 875 1,341 1,141 616 720 832 730 726 775 978 1,555 768 1,550 861 1,472 1,630 800 1,019 1,103 1,368 2,504 2,214 1,034 2,846 35,827 Percentage of NHS treated colorectal cancer patients with a record of a major resection, by cancer network 80 Percentage of patients % major resections 0.7 0 1000 2000 3000 4000 5000 6000 0 7000 Cancer network England average 500 1000 1500 2000 2500 3000 3500 4000 4500 5000 Expected number of patients receiving a major resection Number of HES linked patients 99.8% confidence limits cancer network 99.8% confidence limit The funnel plot of percentages shows that ten cancer networks fall outside the 99.8% confidence limits and therefore have a statistically significant difference from the average for England in the percentage of patients recorded as having a major resection. The funnel plot of age-standardised ratios between observed and expected number of patients with a record of a major resection shows that when age-standardised, seven cancer networks fall outside the 99.8% confidence limits. We cannot exclude the possibility that poor quality data flowing into HES may account for some of the differences seen. Note: It is important to examine the data for these networks more carefully and investigate further as to what factors may underlie the apparent differences including coding quality within HES. The percentages shown in the table above do not take into account any factors such as differences in the age-distributions, co-morbidities or stage at diagnosis of patients between cancer networks. 19 NHS treated patients with a record of a major resection, by sex, age and deprivation quintile, 2004-2006, followed up to 2007 C33-34: Trachea, bronchus and lung Of all newly diagnosed cases of lung cancer registered in England in 2004-2006 (excluding Death Certificate Only registrations), 92% were linked to at least one record within HES. The results presented on these pages show the percentage of these linked, non-DCO patients who had a record of a major resection as part of their treatment. Using OPCS-4 codes, operations including pneumonectomy, bilobectomy and lobectomy as well as excisions of the trachea were included as major resections. The full list of OPCS-4 codes used for lung cancer are included in the appendix. These results are intending to show any differences in the percentage of NHS treated patients with a record of a major resection by different equality groups; age, sex and deprivation. However, caution should be taken when interpreting these results due to limitations in using HES data. These results do not show the proportion of patients who are cured of their cancer through surgery, although it is believed that the large majority of these operations will have been carried out with curative intent. In addition, the treatment of private patients will not be captured. Major resections by age and sex Male HES linked patients Age group % major resections 215 1,177 5,655 13,081 17,352 9,881 47,361 Under 40 40-49 50-59 60-69 70-79 80+ All ages 100% 24% 12% 11% 12% 9% 2% 9% Female 95% Confidence Interval 19% 10% 11% 11% 9% 2% 9% - HES linked patients 30% 14% 12% 12% 10% 3% 9% % major resections 172 1,115 4,401 8,421 11,621 7,431 33,161 21% 17% 14% 13% 9% 2% 9% Persons 95% Confidence Interval 16% 14% 13% 12% 8% 2% 9% - HES linked patients 28% 19% 15% 13% 9% 2% 9% % major resections 387 2,292 10,056 21,502 28,973 17,312 80,522 23% 14% 13% 12% 9% 2% 9% 95% Confidence Interval 19% 13% 12% 12% 9% 2% 9% - 27% 16% 13% 12% 9% 2% 9% Percentage of NHS treated patients with a record of a major resection for lung cancer, by sex and age group 90% Percentage ge of patients 80% 70% 60% Male Female 50% 40% 30% 20% 10% 0% Under 40 40‐49 50‐59 Age group 60‐69 70‐79 80+ Major resections by deprivation quintile and sex Male HES linked patients Deprivation quintile 6,442 8,336 9,545 10,870 12,168 47,361 Quintile 1 - least deprived Quintile 2 Quintile 3 Quintile 4 Quintile 5 - most deprived All quintiles % major resections 9% 9% 9% 9% 8% 9% Female 95% Confidence Interval 9% 8% 9% 8% 8% 9% - HES linked patients 10% 10% 10% 9% 9% 9% % major resections 4,324 5,515 6,648 7,842 8,832 33,161 10% 9% 9% 8% 9% 9% Persons 95% Confidence Interval 9% 8% 9% 8% 9% 9% - HES linked patients 11% 10% 10% 9% 10% 9% % major resections 10,766 13,851 16,193 18,712 21,000 80,522 10% 9% 9% 9% 9% 9% 95% Confidence Interval 9% 9% 9% 8% 8% 9% - 10% 9% 10% 9% 9% 9% Quintile 100% Percentage of NHS treated patients with a record of a major resection for lung cancer, by deprivation quintile 90% Percentage of patients 80% 70% 60% Male 50% Female 40% 30% 20% 10% 0% Least Deprived Quintile2 Quintile3 Quintile4 Most Deprived England Deprivation Quintile The percentage of patients with a record of a major resection is similar for males and females within each age band. However, there was a higher rate for females in the 40-49 age band compared to males. There is a decrease in the percentage of patients with a record of a major resection across age groups. For patients aged 60-69, 12% of patients have a record of a major resection, compared to 2% of patients aged 80 and over. For males, there was a difference (-0.24% per quintile) in the percentage of patients with a record of a major resection that was statistically significant (p=0.02). There was no statistically significant difference in the percentages for females. The percentages by deprivation quintile have not been adjusted for differences in the age structure structure. 20 NHS treated patients with a record of a major resection, by sex and cancer network, 2004-2006 followed up to 2007 C33-34: Trachea, bronchus and lung The results on this page are a reflection of the surgical treatment data currently available through HES, however, there are limitations in the data available and therefore these results are being presented in order to stimulate further discussions with the clinical community as to what factors affect surgery rates and how we can improve data collection. Differences between cancer networks maybe due to higher rates of private patients, later stage of disease at diagnosis, co-morbidities, miscoding or poor data flow. It is important to read the introduction to this report to understand the limitations of data currently available nationally. These results are observational; there is no "good" or "bad" percentage from these results. Better quality data are required in order to understand how surgery rates can affect outcomes. The cancer network relates to the residence of the patient at diagnosis and not the hospital or trust where the patient was treated. Improved data quality and consistency of coding will allow further research into inequalities in cancer to be undertaken to create a better understanding of how patients are treated within the NHS and to target efforts to improve their outcomes. Major resections by cancer network and sex Male HES linked patients Cancer network 1,676 3,385 2,309 2,705 1,290 2,217 1,725 721 776 1,090 1,019 1,156 1,250 1,040 1,620 709 1,622 836 1,613 1,707 800 1,066 1,479 1,708 4,067 2,570 1,259 3,946 47,361 N01 Lancashire and South Cumbria CN N02 Greater Manchester and Cheshire CN N03 Merseyside and Cheshire CN N06 Yorkshire CN N07 Humber and Yorkshire Coast CN N08 North Trent CN N11 Pan Birmingham CN N12 Arden CN N20 Mount Vernon CN N21 West London CN N22 North London CN N23 North East London CN N24 South East London CN N25 South West London CN N26 Peninsula CN N27 Dorset CN N28 Avon, Somerset and Wiltshire CN N29 3 Counties CN N30 Thames Valley CN N31 Central South Coast CN N32 Surrey, West Sussex and Hampshire CN N33 Sussex CN N34 Kent and Medway CN N35 Greater Midlands CN N36 North of England CN N37 Anglia CN N38 Essex CN N39 East Midlands CN England 5% 9% 13% 10% 10% 7% 12% 11% 6% 10% 7% 8% 8% 7% 9% 10% 8% 8% 7% 8% 7% 6% 6% 10% 9% 10% 6% 11% 9% Female 95% Confidence Interval 4% 8% 12% 9% 9% 6% 11% 9% 5% 8% 6% 7% 6% 6% 7% 8% 7% 6% 6% 7% 5% 5% 5% 9% 8% 9% 5% 10% 9% - HES linked patients 6% 10% 15% 11% 12% 8% 14% 13% 8% 11% 9% 10% 9% 9% 10% 12% 9% 10% 8% 9% 9% 7% 8% 12% 10% 11% 7% 12% 9% 18 Age-Standardised Ratio 12 10 8 6 - 7% 10% 14% 12% 11% 9% 13% 17% 8% 14% 12% 11% 9% 13% 11% 14% 11% 10% 9% 8% 11% 8% 9% 15% 10% 11% 7% 12% 9% 2,928 5,894 4,205 4,808 2,175 3,807 2,780 1,176 1,352 1,887 1,748 1,946 2,147 1,837 2,662 1,234 2,720 1,362 2,698 2,868 1,379 1,789 2,435 2,722 7,170 4,187 2,134 6,472 80,522 % major resections 95% Confidence Interval 5% 9% 13% 10% 10% 7% 12% 12% 6% 11% 8% 9% 8% 9% 9% 10% 8% 8% 7% 7% 8% 6% 7% 11% 9% 10% 6% 11% 9% 5% 8% 12% 9% 9% 7% 11% 10% 5% 9% 7% 8% 7% 8% 8% 9% 7% 6% 6% 7% 6% 5% 6% 10% 8% 9% 5% 10% 9% - 6% 10% 14% 11% 11% 8% 13% 14% 7% 12% 9% 10% 9% 10% 10% 12% 10% 9% 8% 8% 9% 7% 8% 13% 9% 11% 7% 12% 9% Indirectly age-standardised ratio: actual number of NHS treated lung cancer patients with a record of a major resection divided by the expected number, by cancer network Networks above 99.8% Confidence limit: N03, N11, N35 & N39 1.6 1.4 1.2 1.0 0.8 0.6 0.4 Networks below 99.8% Confidence limit: N01, N08, N20, N30, N33, N34 & N38 2 4% 8% 11% 9% 8% 7% 10% 11% 4% 10% 7% 7% 6% 9% 8% 8% 8% 6% 6% 5% 6% 4% 6% 11% 8% 8% 4% 9% 9% HES linked patients 1.8 14 4 Persons 95% Confidence Interval 6% 9% 13% 11% 9% 8% 11% 14% 5% 12% 9% 9% 8% 11% 9% 11% 9% 8% 8% 7% 8% 6% 7% 13% 8% 10% 6% 11% 9% 2.0 Networks above 99.8% Confidence limit: N03, N11, N12, N35 & N39 16 % major resections 1,252 2,509 1,896 2,103 885 1,590 1,055 455 576 797 729 790 897 797 1,042 525 1,098 526 1,085 1,161 579 723 956 1,014 3,103 1,617 875 2,526 33,161 Percentage of NHS treated lung cancer patients with a record of a major resection, by cancer network 20 Percentage of patients % major resections Networks below 99.8% Confidence limit: N01, N08, N20, N33, N34 & N38 0.2 0.0 0 0 1000 2000 3000 4000 5000 6000 0 7000 England average 200 300 400 500 600 700 Expected number of patients receiving a major resection Number of HES linked patients Cancer network 100 cancer network 99.8% confidence limits 99.8% confidence limit The funnel plots show that twelve cancer networks fall outside the 99.8% confidence limits and therefore the difference from the average for England in the percentage of patients recorded as having a major resection is statistically significant for these networks. The funnel plot of age-standardised ratios between observed and expected number of patients with a record of a major resection shows that ten cancer networks fall outside the 99.8% confidence limits. We cannot exclude the possibility that poor quality data flowing into HES may account for some of the differences seen. Note: It is important to examine the data for these networks more carefully and investigate further as to what factors may underlie the apparent differences including coding quality within HES. The percentages shown in the table above do not take into account any factors such as differences in the age-distributions, co-morbidities or stage at diagnosis of patients between cancer networks. 21 NHS treated patients with a record of a major resection, by sex, age and deprivation quintile, 2004-2006, followed up to 2007 C50: Breast Of all newly diagnosed cases of breast cancer registered in England in 2004-2006 (excluding Death Certificate Only registrations), 88% were linked to at least one record within HES. The results presented on these pages show the percentage of these linked, non-DCO patients who had a record of a major resection as part of their treatment. Using OPCS-4 codes, operations that have been defined as major resections include total excision of breast, partial excision and excision of lesion of breast and duct of breast. The full list of OPCS-4 codes used for breast cancer is included in the appendix. These results are intending to show any differences in the percentage of NHS treated patients with a record of a major resection by different equality groups; age, sex and deprivation. However, caution should be taken when interpreting these results due to limitations in using HES data. These results do not show the proportion of patients who are cured of their cancer through surgery, although it is believed that the large majority of these operations will have been carried out with curative intent. In addition, the treatment of private patients will not be captured. Major resections by age and sex Male HES linked patients Age group % major resections 18 47 100 173 214 144 696 Under 40 40-49 50-59 60-69 70-79 80+ All ages 100% 83% 85% 85% 87% 76% 64% 78% Female 95% Confidence Interval 61% 72% 77% 81% 70% 56% 75% - HES linked patients 94% 93% 91% 91% 81% 71% 81% % major resections 4,870 14,651 23,849 24,598 17,093 11,933 96,994 87% 89% 90% 90% 81% 51% 83% Persons 95% Confidence Interval 86% 88% 90% 90% 80% 50% 83% - HES linked patients 88% 89% 91% 91% 81% 52% 84% 4,888 14,698 23,949 24,771 17,307 12,077 97,690 % major resections 87% 89% 90% 90% 81% 51% 83% 95% Confidence Interval 86% 88% 90% 90% 80% 50% 83% - 88% 89% 91% 90% 81% 52% 83% Percentage of NHS treated patients with a record of a major resection for breast cancer, by sex and age group 90% Percentage ge of patients 80% 70% 60% Male Female 50% 40% 30% 20% 10% 0% Under 40 40‐49 50‐59 Age group 60‐69 70‐79 80+ Major resections by deprivation quintile and sex Male HES linked patients Deprivation quintile % major resections Female 95% Confidence Interval HES linked patients % major resections 20,413 21,464 20,988 18,983 15,146 96,994 Quintile 1 - least deprived Quintile 2 Quintile 3 Quintile 4 Quintile 5 - most deprived All quintiles 84% 84% 84% 82% 82% 83% Persons 95% Confidence Interval 84% 83% 83% 82% 81% 83% - HES linked patients % major resections 95% Confidence Interval 85% 84% 84% 83% 82% 84% Quintile 100% Percentage of NHS treated patients with a record of a major resection for breast cancer, by deprivation quintile 90% Percentage of patients 80% 70% 60% 50% Female 40% 30% 20% 10% 0% Least Deprived Quintile2 Quintile3 Quintile4 Most Deprived England Deprivation Quintile Overall 83% of NHS treated breast cancer patients have a record of a major resection. There is a decrease with age in the percentage of female breast cancer patients with a record of a major resection aged 70 and over. In patients aged 60-69, 90% of females had a record of a major resection compared to 81% of 70-79 year olds and 51% of female patients aged 80 and over. Across the deprivation quintiles, there was a slight decrease (-0.7%) in the percentage of patients with a record of a major resection for females by deprivation quintile that was statistically significant (p=0.022). The percentages by deprivation quintile have not been adjusted for differences in the age structure. 22 NHS treated patients with a record of a major resection, by sex and cancer network, 2004-2006 followed up to 2007 C50: Breast The results on this page are a reflection of the surgical treatment data currently available through HES, however, there are limitations in the data available and therefore these results are being presented in order to stimulate further discussions with the clinical community as to what factors affect surgery rates and how we can improve data collection. Differences between cancer networks maybe due to higher rates of private patients, later stage of disease at diagnosis, co-morbidities, miscoding or poor data flow. It is important to read the introduction to this report to understand the limitations of data currently available nationally. These results are observational; there is no "good" or "bad" percentage from these results. Better quality data are required in order to understand how surgery rates can affect outcomes. The cancer network relates to the residence of the patient at diagnosis and not the hospital or trust where the patient was treated. Improved data quality and consistency of coding will allow further research into inequalities in cancer to be undertaken to create a better understanding of how patients are treated within the NHS and to target efforts to improve their outcomes. Major resections by cancer network and sex Male HES linked patients Cancer network % major resections Female 95% Confidence Interval HES linked patients 3,294 5,857 4,151 4,729 2,149 3,796 3,397 1,863 1,917 2,464 1,981 1,950 2,261 2,332 4,082 1,782 4,112 2,348 4,252 4,229 2,056 2,344 3,022 4,041 6,361 5,489 2,691 8,044 96,994 N01 Lancashire and South Cumbria CN N02 Greater Manchester and Cheshire CN N03 Merseyside and Cheshire CN N06 Yorkshire CN N07 Humber and Yorkshire Coast CN N08 North Trent CN N11 Pan Birmingham CN N12 Arden CN N20 Mount Vernon CN N21 West London CN N22 North London CN N23 North East London CN N24 South East London CN N25 South West London CN N26 Peninsula CN N27 Dorset CN N28 Avon, Somerset and Wiltshire CN N29 3 Counties CN N30 Thames Valley CN N31 Central South Coast CN N32 Surrey, West Sussex and Hampshire CN N33 Sussex CN N34 Kent and Medway CN N35 Greater Midlands CN N36 North of England CN N37 Anglia CN N38 Essex CN N39 East Midlands CN England Percentage of NHS treated breast cancer patients with a record of a major resection, by cancer network Percentage of patients Networks above 99.8% Confidence limit: N06, N11, N12, N26, N35 & N37 85 82% 83% 85% 87% 85% 82% 88% 87% 81% 81% 81% 80% 81% 80% 85% 79% 82% 83% 85% 84% 83% 82% 79% 86% 83% 85% 82% 83% 83% Persons 95% Confidence Interval 80% 82% 84% 86% 83% 81% 86% 86% 79% 80% 79% 78% 79% 78% 84% 77% 81% 82% 83% 83% 82% 80% 78% 85% 82% 84% 81% 82% 83% - HES linked patients % major resections 95% Confidence Interval 83% 84% 86% 88% 86% 83% 89% 89% 83% 83% 83% 81% 83% 81% 86% 81% 83% 85% 86% 85% 85% 83% 81% 87% 84% 86% 83% 84% 84% Indirectly age-standardised ratio: actual number of NHS treated breast cancer patients with a record of a major resection divided by the expected number, by cancer network 1.2 Age-Standardised Ratio 95 % major resections Networks above 99.8% Confidence limit: None 1.1 1.0 0.9 Networks below 99.8% Confidence limit: N23, N25, N27 & N34 Networks below 99.8% Confidence limit: None 75 0.8 0 2000 4000 6000 8000 0 10000 Cancer network England average 1000 2000 3000 4000 5000 6000 7000 Expected number of patients receiving a major resection Number of HES linked patients 99.8% confidence limits cancer network 99.8% confidence limit The funnel plot of percentages shows that ten cancer networks fall outside the 99.8% confidence limits and therefore the difference from the average for England in the percentage of patients recorded as having a major resection is statistically significant for these cancer networks. However, the funnel plot for age-standardised ratios shows that all networks fall within the 99.8% confidence limits and therefore differences between networks are not statistically significant when age is taken into account. Note: The percentages shown in the table above do not take into account any factors such as differences in the age-distributions, co-morbidities or stage at diagnosis of patients between cancer networks. 23 NHS treated patients with a record of a major resection, by sex, age and deprivation quintile, 2004-2006, followed up to 2007 C53: Cervix Of all newly diagnosed cases of cervical cancer registered in England in 2004-2006 (excluding Death Certificate Only registrations), 89% were linked to at least one record within HES. The results presented on these pages show the percentage of these linked, non-DCO patients who had a record of a major resection as part of their treatment. Using OPCS-4 codes, operations that have been defined as major resections include hysterectomy and hysterocolpectomy. The full list of OPCS-4 codes used for cervical cancer is included in the appendix. These results are intending to show any differences in the percentage of NHS treated patients with a record of a major resection by different equality groups; age, sex and deprivation. However, caution should be taken when interpreting these results due to limitations in using HES data. These results do not show the proportion of patients who are cured of their cancer through surgery, although it is believed that the large majority of these operations will have been carried out with curative intent. In addition, the treatment of private patients will not be captured. Major resections by age and sex Male HES linked patients Age group % major resections Female 95% Confidence Interval HES linked patients % major resections 2,045 1,217 932 676 584 553 6,007 Under 40 40-49 50-59 60-69 70-79 80+ All ages 100% 60% 58% 42% 31% 14% 10% 45% Persons 95% Confidence Interval 58% 55% 39% 28% 12% 8% 43% - HES linked patients % major resections 95% Confidence Interval 62% 61% 45% 35% 17% 13% 46% Percentage of NHS treated patients with a record of a major resection for cancer of the cervix, by sex and age group 90% Percentage ge of patients 80% 70% 60% Female 50% 40% 30% 20% 10% 0% Under 40 40‐49 50‐59 Age group 60‐69 70‐79 80+ Major resections by deprivation quintile and sex Male HES linked patients Deprivation quintile % major resections Female 95% Confidence Interval HES linked patients % major resections 901 1,006 1,175 1,357 1,568 6,007 Quintile 1 - least deprived Quintile 2 Quintile 3 Quintile 4 Quintile 5 - most deprived All quintiles 50% 46% 47% 43% 40% 45% Persons 95% Confidence Interval 47% 43% 44% 41% 37% 43% - HES linked patients % major resections 95% Confidence Interval 53% 49% 50% 46% 42% 46% Quintile 100% Percentage of NHS treated patients with a record of a major resection for cancer of the cervix, by deprivation quintile 90% Percentage of patients 80% 70% 60% 50% Female 40% 30% 20% 10% 0% Least Deprived Quintile2 Quintile3 Quintile4 Most Deprived England Deprivation Quintile Overall, 45% of NHS treated cervical cancer patients have a record of a major resection. There is a decrease with age in the percentage of patients with a record of a major resection. For patients aged under 40, around 60% have a record of a major resection. In patients aged 60-69, 31% have a record of a major resection and for patients aged 80 and over, 10% have a record of a major resection. Across the deprivation quintiles, there was a decrease (-2.3% per quintile) in the percentage of patients with a record of a major resection for females by deprivation quintile that was statistically significant (p=0.01). The percentages by deprivation quintile have not been adjusted for differences in the age structure. 24 NHS treated patients with a record of a major resection, by sex and cancer network, 2004-2006 followed up to 2007 C53: Cervix The results on this page are a reflection of the surgical treatment data currently available through HES, however, there are limitations in the data available and therefore these results are being presented in order to stimulate further discussions with the clinical community as to what factors affect surgery rates and how we can improve data collection. Differences between cancer networks maybe due to higher rates of private patients, later stage of disease at diagnosis, co-morbidities, miscoding or poor data flow. It is important to read the introduction to this report to understand the limitations of data currently available nationally. These results are observational; there is no "good" or "bad" percentage from these results. Better quality data are required in order to understand how surgery rates can affect outcomes. The cancer network relates to the residence of the patient at diagnosis and not the hospital or trust where the patient was treated. Improved data quality and consistency of coding will allow further research into inequalities in cancer to be undertaken to create a better understanding of how patients are treated within the NHS and to target efforts to improve their outcomes. Major resections by cancer network and sex Male HES linked patients Cancer network % major resections Female 95% Confidence Interval HES linked patients 181 424 273 374 210 235 264 116 96 173 123 142 174 148 238 86 249 80 247 229 101 103 153 266 396 234 124 568 6,007 N01 Lancashire and South Cumbria CN N02 Greater Manchester and Cheshire CN N03 Merseyside and Cheshire CN N06 Yorkshire CN N07 Humber and Yorkshire Coast CN N08 North Trent CN N11 Pan Birmingham CN N12 Arden CN N20 Mount Vernon CN N21 West London CN N22 North London CN N23 North East London CN N24 South East London CN N25 South West London CN N26 Peninsula CN N27 Dorset CN N28 Avon, Somerset and Wiltshire CN N29 3 Counties CN N30 Thames Valley CN N31 Central South Coast CN N32 Surrey, West Sussex and Hampshire CN N33 Sussex CN N34 Kent and Medway CN N35 Greater Midlands CN N36 North of England CN N37 Anglia CN N38 Essex CN N39 East Midlands CN England 42% 34% 35% 40% 46% 35% 36% 39% 32% 29% 18% 23% 39% 35% 40% 36% 46% 32% 45% 49% 42% 37% 36% 44% 42% 34% 25% 43% 43% - HES linked patients Age-Standardised Ratio 40 95% Confidence Interval 56% 44% 47% 50% 59% 47% 48% 57% 52% 43% 33% 38% 54% 51% 52% 57% 58% 53% 58% 62% 61% 56% 51% 56% 52% 47% 41% 51% 46% 1.8 50 % major resections Indirectly age-standardised ratio: actual number of NHS treated cervical cancer patients with a record of a major resection divided by the expected number, by cancer network 2.0 Networks above 99.8% Confidence limit: N31 60 Percentage of patients 49% 39% 41% 45% 52% 41% 42% 48% 42% 36% 24% 30% 47% 43% 46% 47% 52% 43% 51% 56% 51% 47% 43% 50% 47% 40% 32% 47% 45% Percentage of NHS treated cervical cancer patients with a record of a major resection, by cancer network 70 Persons 95% Confidence Interval % major resections Networks above 99.8% Confidence limit: None 1.6 1.4 1.2 1.0 0.8 0.6 30 0.4 Networks below 99.8% Confidence limit: N22 & N23 Networks below 99.8% Confidence limit: N22 0.2 20 0.0 0 100 200 300 400 500 600 0 Cancer network England average 50 100 150 200 250 Expected number of patients receiving a major resection Number of HES linked patients 99.8% confidence limits cancer network 99.8% confidence limit The funnel plots show that the majority of cancer networks fall within the 99.8% confidence limits and therefore the difference from the average for England in the percentage of patients recorded as having a major resection is not statistically significant for these cancer networks. However, three cancer networks do fall outside the confidence limits. The funnel plot for age-standardised ratios shows that only one network falls below the 99.8% confidence limit when age is taken into account. We cannot exclude the possibility that poor quality data flowing into HES may account for some of the differences seen. Note: It is important to examine the data for these networks more carefully and investigate further as to what factors may underlie the apparent differences including coding quality within HES. The percentages shown in the table above do not take into account any factors such as differences in the age-distributions, co-morbidities or stage at diagnosis of patients between cancer networks. 25 NHS treated patients with a record of a major resection, by sex, age and deprivation quintile, 2004-2006, followed up to 2007 C54-55: Uterus Of all newly diagnosed cases of uterine cancer registered in England in 2004-2006 (excluding Death Certificate Only registrations), 91% were linked to at least one record within HES. The results presented on these pages show the percentage of these linked, non-DCO patients who had a record of a major resection as part of their treatment. Using OPCS-4 codes, operations that have been defined as major resections include hysterectomy and hysterocolpectomy. The full list of OPCS-4 codes used for uterine cancer is included in the appendix. These results are intending to show any differences in the percentage of NHS treated patients with a record of a major resection by different equality groups; age, sex and deprivation. However, caution should be taken when interpreting these results due to limitations in using HES data. These results do not show the proportion of patients who are cured of their cancer through surgery, although it is believed that the large majority of these operations will have been carried out with curative intent. In addition, the treatment of private patients will not be captured. Major resections by age and sex Male HES linked patients Age group % major resections Female 95% Confidence Interval HES linked patients % major resections 204 837 3,556 4,731 3,900 2,146 15,374 Under 40 40-49 50-59 60-69 70-79 80+ All ages 100% 80% 87% 89% 89% 83% 65% 84% Persons 95% Confidence Interval 74% 85% 88% 88% 82% 63% 84% - HES linked patients % major resections 95% Confidence Interval 85% 89% 90% 90% 85% 67% 85% Percentage of NHS treated patients with a record of a major resection for cancer of the uterus, by sex and age group 90% Percentage ge of patients 80% 70% 60% Female 50% 40% 30% 20% 10% 0% Under 40 40‐49 50‐59 Age group 60‐69 70‐79 80+ Major resections by deprivation quintile and sex Male HES linked patients Deprivation quintile % major resections Female 95% Confidence Interval HES linked patients % major resections 2,943 3,427 3,402 3,033 2,569 15,374 Quintile 1 - least deprived Quintile 2 Quintile 3 Quintile 4 Quintile 5 - most deprived All quintiles 83% 86% 84% 84% 83% 84% Persons 95% Confidence Interval 82% 84% 83% 83% 82% 84% - HES linked patients % major resections 95% Confidence Interval 84% 87% 85% 86% 85% 85% Quintile 100% Percentage of NHS treated patients with a record of a major resection for cancer of the uterus, by deprivation quintile 90% Percentage of patients 80% 70% 60% 50% Female 40% 30% 20% 10% 0% Least Deprived Quintile2 Quintile3 Quintile4 Most Deprived England Deprivation Quintile Overall, 84% of NHS treated uterine cancer patients have a record of a major resection. There is a decrease with age in the percentage of older uterine cancer patients with a record of a major resection. For patients aged 60-69, 89% have a record of a major resection. In patients aged 70-79, 83% had a record of a major resection and for patients aged 80 and over, 65% had a record of a major resection. Across deprivation quintiles, there was no statistically significant change in the percentage of patients with a record of a major resection for females. The percentages by deprivation quintile have not been adjusted for differences in the age structure. 26 NHS treated patients with a record of a major resection, by sex and cancer network, 2004-2006 followed up to 2007 C54-55: Uterus The results on this page are a reflection of the surgical treatment data currently available through HES, however, there are limitations in the data available and therefore these results are being presented in order to stimulate further discussions with the clinical community as to what factors affect surgery rates and how we can improve data collection. Differences between cancer networks maybe due to higher rates of private patients, later stage of disease at diagnosis, co-morbidities, miscoding or poor data flow. It is important to read the introduction to this report to understand the limitations of data currently available nationally. These results are observational; there is no "good" or "bad" percentage from these results. Better quality data are required in order to understand how surgery rates can affect outcomes. The cancer network relates to the residence of the patient at diagnosis and not the hospital or trust where the patient was treated. Improved data quality and consistency of coding will allow further research into inequalities in cancer to be undertaken to create a better understanding of how patients are treated within the NHS and to target efforts to improve their outcomes. Major resections by cancer network and sex Male HES linked patients Cancer network % major resections Female 95% Confidence Interval HES linked patients 513 868 560 694 397 617 606 315 268 367 374 368 372 368 679 294 658 373 607 609 290 378 502 645 893 993 457 1,309 15,374 N01 Lancashire and South Cumbria CN N02 Greater Manchester and Cheshire CN N03 Merseyside and Cheshire CN N06 Yorkshire CN N07 Humber and Yorkshire Coast CN N08 North Trent CN N11 Pan Birmingham CN N12 Arden CN N20 Mount Vernon CN N21 West London CN N22 North London CN N23 North East London CN N24 South East London CN N25 South West London CN N26 Peninsula CN N27 Dorset CN N28 Avon, Somerset and Wiltshire CN N29 3 Counties CN N30 Thames Valley CN N31 Central South Coast CN N32 Surrey, West Sussex and Hampshire CN N33 Sussex CN N34 Kent and Medway CN N35 Greater Midlands CN N36 North of England CN N37 Anglia CN N38 Essex CN N39 East Midlands CN England Percentage of NHS treated uterine cancer patients with a record of a major resection, by cancer network 100 Persons 95% Confidence Interval 82% 79% 81% 81% 90% 84% 87% 85% 81% 83% 80% 81% 86% 82% 85% 77% 85% 82% 83% 83% 84% 87% 78% 91% 91% 88% 86% 84% 84% 79% 76% 77% 77% 87% 81% 84% 80% 75% 79% 75% 77% 82% 78% 83% 72% 82% 78% 79% 80% 79% 83% 75% 88% 89% 86% 83% 82% 84% - HES linked patients Age-Standardised Ratio 80 Networks below 99.8% Confidence limit: N02 Networks above 99.8% Confidence limit: None 1.2 1.0 0.8 Networks below 99.8% Confidence limit: None 0.6 70 95% Confidence Interval 86% 81% 84% 83% 93% 87% 90% 88% 85% 87% 83% 85% 89% 85% 88% 82% 88% 85% 86% 86% 88% 90% 82% 93% 92% 90% 89% 86% 85% 1.4 90 % major resections Indirectly age-standardised ratio: actual number of NHS treated uterine cancer patients with a record of a major resection divided by the expected number, by cancer network 1.6 Networks above 99.8% Confidence limit: N07, N35, N36 & N37 Percentage of patients % major resections 0.4 0 200 400 600 800 1000 1200 1400 0 Number of HES linked patients Cancer network England average 200 400 600 800 1000 1200 Expected number of patients receiving a major resection 99.8% confidence limits cancer network 99.8% confidence limit The funnel plot of percentages shows that five cancer networks fall outside the 99.8% confidence limits and therefore have a statistically significant difference from the average for England in the percentage of patients recorded as having a major resection. However, the funnel plot of age-standardised ratios shows that all networks fall within the 99.8% confidence limits. Note: The percentages shown in the table above do not take into account any factors such as differences in the age-distributions, co-morbidities or stage at diagnosis of patients between cancer networks. 27 NHS treated patients with a record of a major resection, by sex, age and deprivation quintile, 2004-2006, followed up to 2007 C56: Ovary Of all newly diagnosed cases of ovarian cancer registered in England in 2004-2006 (excluding Death Certificate Only registrations), 91% were linked to at least one record within HES. The results presented on these pages show the percentage of these linked, non-DCO patients who had a record of a major resection as part of their treatment. Using OPCS-4 codes, operations that have been defined as major resections include oophorectomys and salpingoophorectomy, and other excisions of ovary and uterus. The full list of OPCS-4 codes used for ovarian cancer is included in the appendix. These results are intending to show any differences in the percentage of NHS treated patients with a record of a major resection by different equality groups; age, sex and deprivation. However, caution should be taken when interpreting these results due to limitations in using HES data. These results do not show the proportion of patients who are cured of their cancer through surgery, although it is believed that the large majority of these operations will have been carried out with curative intent. In addition, the treatment of private patients will not be captured. Major resections by age and sex Male HES linked patients Age group % major resections Female 95% Confidence Interval HES linked patients % major resections 888 1,324 2,801 3,687 3,502 2,242 14,444 Under 40 40-49 50-59 60-69 70-79 80+ All ages 100% 83% 82% 74% 63% 48% 26% 59% Persons 95% Confidence Interval 80% 80% 72% 62% 46% 24% 58% - HES linked patients % major resections 95% Confidence Interval 85% 84% 75% 65% 49% 28% 59% Percentage of NHS treated patients with a record of a major resection for ovarian cancer, by sex and age group 90% Percentage ge of patients 80% 70% 60% Female 50% 40% 30% 20% 10% 0% Under 40 40‐49 50‐59 Age group 60‐69 70‐79 80+ Major resections by deprivation quintile and sex Male HES linked patients Deprivation quintile % major resections Female 95% Confidence Interval HES linked patients % major resections 2,883 3,132 3,210 2,887 2,332 14,444 Quintile 1 - least deprived Quintile 2 Quintile 3 Quintile 4 Quintile 5 - most deprived All quintiles 60% 59% 58% 58% 59% 59% Persons 95% Confidence Interval 58% 57% 56% 56% 57% 58% - HES linked patients % major resections 95% Confidence Interval 62% 61% 59% 60% 61% 59% Quintile 100% Percentage of NHS treated patients with a record of a major resection for ovarian cancer, by deprivation quintile 90% Percentage of patients 80% 70% 60% 50% Female 40% 30% 20% 10% 0% Least Deprived Quintile2 Quintile3 Quintile4 Most Deprived England Deprivation Quintile Overall, 59% of NHS treated ovarian cancer patients have a record of a major resection. However, there is a decrease with age in the percentage of ovarian cancer patients with a record of a major resection. For patients aged under 40 and 40-49, around 83% have a record of a major resection. In patients aged 60-69, 63% have a record of a major resection and for patients aged 80 and over, 26% have a record of a major resection. Across the deprivation quintiles, there was no statistically significant change in the percentage of patients with a record of a major resection for females. The percentages by deprivation quintile have not been adjusted for differences in the age structure. 28 NHS treated patients with a record of a major resection, by sex and cancer network, 2004-2006 followed up to 2007 C56: Ovary The results on this page are a reflection of the surgical treatment data currently available through HES, however, there are limitations in the data available and therefore these results are being presented in order to stimulate further discussions with the clinical community as to what factors affect surgery rates and how we can improve data collection. Differences between cancer networks maybe due to higher rates of private patients, later stage of disease at diagnosis, co-morbidities, miscoding or poor data flow. It is important to read the introduction to this report to understand the limitations of data currently available nationally. These results are observational; there is no "good" or "bad" percentage from these results. Better quality data are required in order to understand how surgery rates can affect outcomes. The cancer network relates to the residence of the patient at diagnosis and not the hospital or trust where the patient was treated. Improved data quality and consistency of coding will allow further research into inequalities in cancer to be undertaken to create a better understanding of how patients are treated within the NHS and to target efforts to improve their outcomes. Major resections by cancer network and sex Male HES linked patients Cancer network % major resections Female 95% Confidence Interval HES linked patients 521 896 596 606 292 570 497 275 257 310 280 266 301 366 748 300 697 332 632 645 275 324 407 619 960 809 440 1,223 14,444 N01 Lancashire and South Cumbria CN N02 Greater Manchester and Cheshire CN N03 Merseyside and Cheshire CN N06 Yorkshire CN N07 Humber and Yorkshire Coast CN N08 North Trent CN N11 Pan Birmingham CN N12 Arden CN N20 Mount Vernon CN N21 West London CN N22 North London CN N23 North East London CN N24 South East London CN N25 South West London CN N26 Peninsula CN N27 Dorset CN N28 Avon, Somerset and Wiltshire CN N29 3 Counties CN N30 Thames Valley CN N31 Central South Coast CN N32 Surrey, West Sussex and Hampshire CN N33 Sussex CN N34 Kent and Medway CN N35 Greater Midlands CN N36 North of England CN N37 Anglia CN N38 Essex CN N39 East Midlands CN England Percentage of NHS treated ovarian cancer patients with a record of a major resection, by cancer network Persons 95% Confidence Interval 46% 51% 49% 55% 48% 59% 61% 53% 55% 45% 52% 49% 47% 57% 48% 54% 60% 56% 54% 50% 55% 40% 51% 58% 68% 58% 56% 58% 58% - HES linked patients 60 95% Confidence Interval % major resections 55% 57% 57% 63% 60% 67% 69% 65% 66% 56% 64% 61% 58% 67% 55% 65% 67% 66% 62% 58% 66% 51% 61% 66% 74% 64% 65% 63% 59% Indirectly age-standardised ratio: actual number of NHS treated ovarian cancer patients with a record of a major resection divided by the expected number, by cancer network 1.8 Networks above 99.8% Confidence limit: N36 70 51% 54% 53% 59% 54% 64% 65% 59% 61% 50% 58% 55% 52% 62% 52% 60% 63% 61% 58% 54% 61% 46% 56% 62% 71% 61% 61% 60% 59% 2.0 Age-Standardised Ratio Percentage of patients 80 % major resections Networks above 99.8% Confidence limit: N36 1.6 1.4 1.2 1.0 0.8 0.6 50 0.4 Networks below 99.8% Confidence limit: N01, N26 & N33 Networks below 99.8% Confidence limit: N33 0.2 0.0 40 0 200 400 600 800 1000 0 1200 Cancer network England average 100 200 300 400 500 600 700 Expected number of patients receiving a major resection Number of HES linked patients 99.8% confidence limits cancer network 99.8% confidence limit The funnel plot of percentages show that four cancer networks fall outside the 99.8% confidence limits and therefore the difference is statistically significant from the average for England in the percentage of patients recorded as having a major resection for these networks. The funnel plot of age-standardised ratios shows that only two networks falls outside the 99.8% confidence limits. We cannot exclude the possibility that poor quality data flowing into HES may account for some of the differences seen. Note: It is important to examine the data for these networks more carefully and investigate further as to what factors may underlie the apparent differences including coding quality within HES. The percentages shown in the table above do not take into account any factors such as differences in the age-distributions, co-morbidities or stage at diagnosis of patients between cancer networks. 29 NHS treated patients with a record of a major resection, by sex, age and deprivation quintile, 2004-2006, followed up to 2007 C61: Prostate Of all newly diagnosed cases of prostate cancer registered in England in 2004-2006 (excluding Death Certificate Only registrations), 73% were linked to at least one record within HES. The results presented on these pages show the percentage of these linked, non-DCO patients who had a record of a major resection as part of their treatment. Using OPCS-4 codes, operations such as total/radical prostatectomy and perineal prostatectomy were included as major resections. The full list of OPCS-4 codes used for prostate cancer are included in the appendix. These results are intending to show any differences in the percentage of NHS treated patients with a record of a major resection by different equality groups; age, sex and deprivation. However, caution should be taken when interpreting these results due to limitations in using HES data. These results do not show the proportion of patients who are cured of their cancer through surgery, although it is believed that the large majority of these operations will have been carried out with curative intent. In addition, the treatment of private patients will not be captured. For prostate cancer, a larger proportion of patients are not treated as inpatients or day cases (see appendix 2). Please note that only patients who have a record of being treated in an inpatient or day case setting are included in these analyses. Major resections by age and sex Male HES linked patients Age group % major resections 26 516 6,743 19,835 23,172 13,648 63,940 Under 40 40-49 50-59 60-69 70-79 80+ All ages 100% 19% 35% 30% 19% 2% 0% 10% Female 95% Confidence Interval 9% 31% 29% 18% 2% 0% 10% - HES linked patients % major resections Persons 95% Confidence Interval HES linked patients % major resections 95% Confidence Interval 38% 39% 31% 19% 2% 0% 10% Percentage of NHS treated patients with a record of a major resection for prostate cancer, by sex and age group 90% Percentage ge of patients 80% 70% 60% Male 50% 40% 30% 20% 10% 0% Under 40 40‐49 50‐59 Age group 60‐69 70‐79 80+ Major resections by deprivation quintile and sex Male HES linked patients Deprivation quintile 14,111 14,869 13,734 11,671 9,555 63,940 Quintile 1 - least deprived Quintile 2 Quintile 3 Quintile 4 Quintile 5 - most deprived All quintiles % major resections 13% 11% 9% 9% 7% 10% Female 95% Confidence Interval 12% 10% 9% 8% 7% 10% - HES linked patients % major resections Persons 95% Confidence Interval HES linked patients % major resections 95% Confidence Interval 13% 12% 10% 9% 8% 10% Quintile 100% Percentage of NHS treated patients with a record of a major resection for prostate cancer, by deprivation quintile 90% Percentage of patients 80% 70% 60% Male 50% 40% 30% 20% 10% 0% Least Deprived Quintile2 Quintile3 Quintile4 Most Deprived England Deprivation Quintile Overall, 10% of NHS treated prostate cancer patients had a record of a major resection for their cancer. There is variation with age with 35% of patients aged 40-49 receiving a major resection, 19% of patients aged 60-69 and less than 0.1% of patients aged 80 and over. There was a decrease in the percentage of patients with a record of a major resection for males by deprivation quintile that was statistically significant (-1.2%, p=0.001). The percentages by deprivation quintile have not been adjusted for differences in the age structure. 30 NHS treated patients with a record of a major resection, by sex and cancer network, 2004-2006 followed up to 2007 C61: Prostate The results on this page are a reflection of the surgical treatment data currently available through HES, however, there are limitations in the data available and therefore these results are being presented in order to stimulate further discussions with the clinical community as to what factors affect surgery rates and how we can improve data collection. Differences between cancer networks maybe due to higher rates of private patients, later stage of disease at diagnosis, co-morbidities, miscoding or poor data flow. It is important to read the introduction to this report to understand the limitations of data currently available nationally. These results are observational; there is no "good" or "bad" percentage from these results. Better quality data are required in order to understand how surgery rates can affect outcomes. The cancer network relates to the residence of the patient at diagnosis and not the hospital or trust where the patient was treated. Improved data quality and consistency of coding will allow further research into inequalities in cancer to be undertaken to create a better understanding of how patients are treated within the NHS and to target efforts to improve their outcomes. Major resections by cancer network and sex Male HES linked patients Cancer network N01 Lancashire and South Cumbria CN N02 Greater Manchester and Cheshire CN N03 Merseyside and Cheshire CN N06 Yorkshire CN N07 Humber and Yorkshire Coast CN N08 North Trent CN N11 Pan Birmingham CN N12 Arden CN N20 Mount Vernon CN N21 West London CN N22 North London CN N23 North East London CN N24 South East London CN N25 South West London CN N26 Peninsula CN N27 Dorset CN N28 Avon, Somerset and Wiltshire CN N29 3 Counties CN N30 Thames Valley CN N31 Central South Coast CN N32 Surrey, West Sussex and Hampshire CN N33 Sussex CN N34 Kent and Medway CN N35 Greater Midlands CN N36 North of England CN N37 Anglia CN N38 Essex CN N39 East Midlands CN England 2,760 4,114 2,791 3,279 1,480 2,286 2,715 1,138 1,195 1,412 1,547 1,310 1,177 1,372 2,961 1,423 3,140 1,398 2,477 2,539 1,075 1,472 1,656 2,049 3,781 4,167 1,435 5,791 63,940 % major resections 8% 10% 7% 12% 10% 9% 13% 14% 7% 13% 13% 12% 10% 10% 4% 17% 12% 7% 14% 13% 11% 11% 14% 9% 9% 8% 8% 7% 10% 7% 9% 6% 11% 8% 8% 12% 12% 6% 12% 12% 10% 8% 9% 3% 15% 11% 6% 13% 12% 9% 10% 13% 7% 9% 7% 6% 7% 10% - HES linked patients 18 1.8 Age-Standardised Ratio 14 12 10 8 6 4 % major resections 95% Confidence Interval Networks above 99.8% Networks above 99.8% Confidence Confidence limit:limit: N11, N27, N28, N30, N31 & N34 N11, N12, N27, N28, N30, N31 & 1.6 N34 1.4 1.2 1.0 0.8 0.6 Networks below 99.8% Networks below 99.8% Confidence limit:limit: Confidence N01, N03, N20, N26 & N39 N01, N03, N20, N26 & N39 0.4 Networks below 99.8% Confidence limit: N01, N03, N20, N26, N29, N37, N38 & N39 2 HES linked patients Indirectly age-standardised ratio: actual number of NHS treated prostate cancer patients with a record of a major resection divided by the expected number, by cancer network 2.0 Networks above 99.8% Confidence limit: N06, N11, N12, N21, N22, N27, N28, N30, N31 & N34 16 Persons 95% Confidence Interval % major resections 9% 11% 8% 13% 11% 10% 14% 16% 9% 15% 15% 13% 12% 12% 5% 19% 14% 9% 16% 14% 13% 13% 16% 10% 10% 9% 9% 8% 10% Percentage of NHS treated prostate cancer patients with a record of a major resection, by cancer network 20 Percentage of patients Female 95% Confidence Interval 0.2 0.0 0 0 1000 2000 3000 4000 5000 0 6000 England average 200 300 400 500 600 Expected number of patients receiving a major resection Number of HES linked patients Cancer network 100 99.8% confidence limits cancer network 99.8% confidence limit The funnel plot on percentages shows that there is large variation between networks in the proportion of patients with a record of a major resection. The majority of cancer networks fall outside the 99.8% confidence limits and therefore have a statistically significant difference from the average for England in the percentage of patients with a record of a major resection. The funnel plot of age-standardised ratios shows less variation between cancer networks but eleven cancer networks do still fall outside the 99.8% confidence intervals. We cannot exclude the possibility that poor quality data flowing into HES may also account for some of the differences seen. Note: It is important to examine the data for these networks more carefully and investigate further as to what factors may underlie the apparent differences including coding quality within HES. The percentages shown in the table above do not take into account any factors such as differences in the age-distributions, co-morbidities or stage at diagnosis of patients between cancer networks. 31 NHS treated patients with a record of a major resection, by sex, age and deprivation quintile, 2004-2006, followed up to 2007 C64-C66 & C68: Kidney Of all newly diagnosed cases of kidney cancer registered in England in 2004-2006 (excluding Death Certificate Only registrations), 92% were linked to at least one record within HES. The results presented on these pages show the percentage of these linked, non-DCO patients who had a record of a major resection as part of their treatment. Using OPCS-4 codes, operations that have been defined as major resections include total and partial nephrectectomy, and total and partial excisions of the kidney. The full list of OPCS-4 codes used for kidney cancer are included in the appendix. These results are intending to show any differences in the percentage of NHS treated patients with a record of a major resection by different equality groups; age, sex and deprivation. However, caution should be taken when interpreting these results due to limitations in using HES data. These results do not show the proportion of patients who are cured of their cancer through surgery, although it is believed that the large majority of these operations will have been carried out with curative intent. In addition, the treatment of private patients will not be captured. Major resections by age and sex Male HES linked patients Age group % major resections 328 689 1,854 2,718 3,094 1,552 10,235 Under 40 40-49 50-59 60-69 70-79 80+ All ages 100% 83% 77% 73% 65% 56% 30% 60% Female 95% Confidence Interval 78% 74% 71% 63% 54% 27% 59% - HES linked patients 86% 80% 75% 67% 57% 32% 61% % major resections 291 387 943 1,430 1,813 1,215 6,079 80% 80% 76% 68% 57% 27% 59% Persons 95% Confidence Interval 75% 76% 73% 66% 55% 25% 58% - HES linked patients 84% 84% 79% 71% 60% 30% 61% % major resections 619 1,076 2,797 4,148 4,907 2,767 16,314 81% 78% 74% 66% 56% 29% 60% 95% Confidence Interval 78% 76% 72% 65% 55% 27% 59% - 84% 81% 76% 68% 58% 30% 60% Percentage of NHS treated patients with a record of a major resection for kidney cancer, by sex and age group 90% Percentage ge of patients 80% 70% 60% Male Female 50% 40% 30% 20% 10% 0% Under 40 40‐49 50‐59 Age group 60‐69 70‐79 80+ Major resections by deprivation quintile and sex Male HES linked patients Deprivation quintile 2,060 2,223 2,240 2,019 1,693 10,235 Quintile 1 - least deprived Quintile 2 Quintile 3 Quintile 4 Quintile 5 - most deprived All quintiles % major resections 63% 59% 60% 59% 58% 60% Female 95% Confidence Interval 61% 57% 58% 56% 55% 59% - HES linked patients 65% 61% 62% 61% 60% 61% % major resections 1,132 1,239 1,279 1,259 1,170 6,079 59% 61% 60% 57% 59% 59% Persons 95% Confidence Interval 56% 59% 57% 54% 57% 58% - HES linked patients 62% 64% 62% 60% 62% 61% % major resections 3,192 3,462 3,519 3,278 2,863 16,314 62% 60% 60% 58% 58% 60% 95% Confidence Interval 60% 58% 58% 56% 57% 59% - 63% 62% 61% 60% 60% 60% Quintile 100% Percentage of NHS treated patients with a record of a major resection for kidney cancer, by deprivation quintile 90% Percentage of patients 80% 70% 60% Male 50% Female 40% 30% 20% 10% 0% Least Deprived Quintile2 Quintile3 Quintile4 Most Deprived England Deprivation Quintile The difference between males and females within each age band in the percentage of patients with a record of a major resection is not statistically significant. There is a decrease with age in the percentage of kidney cancer patients with a record of a major resection. In patients aged 50-59, 74% had a record of a major resection compared to 56% of 70-79 year olds and 29% of patients aged 80 and over. Across the deprivation quintiles, there was no statistically significant change in the percentage of patients with a record of a major resection for either males or females. The percentages by deprivation quintile have not been adjusted for differences in the age structure within each quintile. 32 NHS treated patients with a record of a major resection, by sex and cancer network, 2004-2006 followed up to 2007 C64-C66 & C68: Kidney The results on this page are a reflection of the surgical treatment data currently available through HES, however, there are limitations in the data available and therefore these results are being presented in order to stimulate further discussions with the clinical community as to what factors affect surgery rates and how we can improve data collection. Differences between cancer networks maybe due to higher rates of private patients, later stage of disease at diagnosis, co-morbidities, miscoding or poor data flow. It is important to read the introduction to this report to understand the limitations of data currently available nationally. These results are observational; there is no "good" or "bad" percentage from these results. Better quality data are required in order to understand how surgery rates can affect outcomes. The cancer network relates to the residence of the patient at diagnosis and not the hospital or trust where the patient was treated. Improved data quality and consistency of coding will allow further research into inequalities in cancer to be undertaken to create a better understanding of how patients are treated within the NHS and to target efforts to improve their outcomes. Major resections by cancer network and sex Male HES linked patients Cancer network 324 558 370 586 281 450 292 126 180 225 220 199 222 240 475 263 467 225 430 468 215 229 306 329 749 652 281 873 10,235 N01 Lancashire and South Cumbria CN N02 Greater Manchester and Cheshire CN N03 Merseyside and Cheshire CN N06 Yorkshire CN N07 Humber and Yorkshire Coast CN N08 North Trent CN N11 Pan Birmingham CN N12 Arden CN N20 Mount Vernon CN N21 West London CN N22 North London CN N23 North East London CN N24 South East London CN N25 South West London CN N26 Peninsula CN N27 Dorset CN N28 Avon, Somerset and Wiltshire CN N29 3 Counties CN N30 Thames Valley CN N31 Central South Coast CN N32 Surrey, West Sussex and Hampshire CN N33 Sussex CN N34 Kent and Medway CN N35 Greater Midlands CN N36 North of England CN N37 Anglia CN N38 Essex CN N39 East Midlands CN England % major resections 63% 58% 62% 60% 58% 51% 68% 66% 67% 68% 65% 55% 64% 58% 61% 56% 52% 62% 69% 52% 52% 59% 56% 66% 61% 57% 59% 60% 60% 58% 54% 57% 56% 52% 47% 62% 57% 59% 62% 58% 48% 58% 52% 57% 49% 47% 56% 65% 48% 45% 53% 50% 61% 57% 53% 53% 56% 59% - HES linked patients 68% 62% 67% 64% 64% 56% 73% 74% 73% 74% 71% 62% 70% 64% 66% 61% 56% 68% 73% 57% 59% 66% 61% 71% 64% 61% 65% 63% 61% 59% 59% 60% 61% 53% 55% 74% 74% 69% 70% 71% 59% 61% 54% 59% 55% 48% 67% 64% 55% 46% 56% 55% 67% 59% 58% 63% 56% 59% Persons 95% Confidence Interval 52% 53% 54% 56% 45% 49% 67% 64% 60% 61% 63% 50% 52% 46% 53% 46% 43% 59% 58% 49% 37% 49% 48% 60% 55% 53% 56% 51% 58% - HES linked patients 66% 64% 67% 66% 61% 61% 80% 82% 77% 78% 78% 68% 70% 62% 65% 63% 54% 75% 70% 61% 55% 64% 61% 73% 63% 63% 70% 60% 61% 504 899 585 961 422 717 476 219 286 326 365 305 341 373 753 380 748 351 674 748 333 385 506 536 1,265 1,024 450 1,382 16,314 62% 58% 62% 61% 56% 53% 70% 69% 67% 69% 67% 57% 63% 57% 61% 55% 50% 64% 67% 53% 50% 58% 55% 66% 60% 57% 61% 58% 60% 1.8 Age-Standardised Ratio 50 66% 61% 66% 64% 61% 56% 74% 75% 73% 74% 72% 62% 68% 62% 64% 60% 54% 69% 71% 57% 55% 63% 60% 70% 63% 60% 65% 61% 60% 1.2 1.0 0.8 0.6 Networks below 99.8% Confidence limit: N28 0.2 40 - 1.4 0.4 Networks below 99.8% Confidence limit: N07, N28, N31 & N32 57% 55% 58% 58% 52% 49% 66% 63% 62% 63% 62% 51% 58% 52% 57% 50% 47% 59% 64% 50% 45% 53% 51% 62% 57% 54% 56% 55% 59% Networks above 99.8% Confidence limit: None 1.6 60 95% Confidence Interval % major resections Indirectly age-standardised ratio: actual number of NHS treated kidney cancer patients with a record of a major resection divided by the expected number, by cancer network 2.0 Networks above 99.8% Confidence limit: N11, N12, N21, N30 & N35 70 % major resections 180 341 215 375 141 267 184 93 106 101 145 106 119 133 278 117 281 126 244 280 118 156 200 207 516 372 169 509 6,079 Percentage of NHS treated kidney cancer patients with a record of a major resection, by cancer network 80 Percentage of patients Female 95% Confidence Interval 0.0 0 200 400 600 800 1000 1200 0 1400 England average 200 300 400 500 600 700 800 Expected number of patients receiving a major resection Number of HES linked patients Cancer network 100 99.8% confidence limits cancer network 99.8% confidence limit The funnel plot of percentages shows that nine cancer networks fall outside the 99.8% confidence limits and therefore do not have a statistically significant difference from the average for England in the percentage of patients recorded as having a major resection. The funnel plot of age-standardised ratios between observed and expected number of patients with a record of a major resection shows that one network falls outside the 99.8% confidence limits. We cannot exclude the possibility that poor quality data flowing into HES may still account for some of the differences seen. Note: It is important to examine the data for these networks more carefully and investigate further as to what other factors may underlie the apparent differences including coding quality within HES. The percentages shown in the table above do not take into account any factors such as differences in the age-distributions, comorbidities or stage at diagnosis of patients between cancer networks. 33 NHS treated patients with a record of a major resection, by sex, age and deprivation quintile, 2004-2006, followed up to 2007 C67: Bladder Of all newly diagnosed cases of bladder cancer registered in England in 2004-2006 (excluding Death Certificate Only registrations), 96% were linked to at least one record within HES. The results presented on these pages show the percentage of these linked, non-DCO patients who had a record of a major resection as part of their treatment. For these analyses, only operations that would remove the whole tumour for bladder cancer have been included. A larger percentage of patients will undergo other treatment for their tumour. Using OPCS-4 codes, operations that have been defined as major resections include Cystoprostatectomy, Cystourethrectomy, Cystectomy NEC, Other specified total excision of bladder and Unspecified total excision of bladder. Other operations such as endoscopic operations, and operations of the Urethra (that are common for bladder cancer patients) have not been included. The full list of OPCS-4 codes used for bladder cancer are included in the appendix. These results are intending to show any differences in the percentage of NHS treated patients with a record of a major resection by different equality groups; age, sex and deprivation. However, caution should be taken when interpreting these results due to limitations in using HES data. These results do not show the proportion of patients who are cured of their cancer through surgery, although it is believed that the large majority of these operations will have been carried out with curative intent. In addition, the treatment of private patients will not be captured. Major resections by age and sex Male HES linked patients Age group % major resections 95 338 1,459 3,797 6,335 4,946 16,970 Under 40 40-49 50-59 60-69 70-79 80+ All ages 100% 25% 20% 23% 17% 10% 2% 11% Female 95% Confidence Interval 18% 16% 21% 16% 9% 2% 10% - HES linked patients 35% 24% 25% 19% 11% 2% 11% % major resections 60 152 496 1,167 2,078 2,639 6,592 27% 31% 20% 18% 11% 1% 10% Persons 95% Confidence Interval 17% 24% 17% 16% 10% 1% 9% - HES linked patients 39% 39% 24% 21% 13% 2% 11% % major resections 155 490 1,955 4,964 8,413 7,585 23,562 26% 23% 22% 18% 10% 2% 10% 95% Confidence Interval 20% 20% 21% 16% 10% 1% 10% - 33% 27% 24% 19% 11% 2% 11% Percentage of NHS treated patients with a record of a major resection for bladder cancer, by sex and age group 90% Percentage ge of patients 80% 70% 60% Male Female 50% 40% 30% 20% 10% 0% Under 40 40‐49 50‐59 Age group 60‐69 70‐79 80+ Major resections by deprivation quintile and sex Male HES linked patients Deprivation quintile 3,196 3,601 3,673 3,522 2,978 16,970 Quintile 1 - least deprived Quintile 2 Quintile 3 Quintile 4 Quintile 5 - most deprived All quintiles % major resections 12% 11% 10% 11% 10% 11% Female 95% Confidence Interval 11% 10% 9% 10% 9% 10% - HES linked patients 14% 12% 11% 12% 11% 11% % major resections 1,139 1,296 1,356 1,467 1,334 6,592 13% 10% 8% 10% 9% 10% Persons 95% Confidence Interval 11% 8% 7% 8% 7% 9% - HES linked patients 15% 12% 10% 11% 10% 11% % major resections 4,335 4,897 5,029 4,989 4,312 23,562 13% 11% 9% 10% 9% 10% 95% Confidence Interval 12% 10% 9% 10% 8% 10% - 14% 12% 10% 11% 10% 11% Quintile 100% Percentage of NHS treated patients with a record of a major resection for bladder cancer, by deprivation quintile 90% Percentage of patients 80% 70% 60% Male 50% Female 40% 30% 20% 10% 0% Least Deprived Quintile2 Quintile3 Quintile4 Most Deprived England Deprivation Quintile The percentage of patients with a record of a major resection is very similar for males and females within each age band. There is a decrease with age in the percentage of bladder cancer patients with a record of a major resection. In patients aged 50-59, 22% have a record of a major resection compared to 10% of 70-79 year olds and 2% patients aged 80 and over. Across the deprivation quintiles, there was no statistically significant change in the percentage of patients with a record of a major resection for either males or females. The percentages by deprivation quintile have not been adjusted for differences in the age structure. 34 NHS treated patients with a record of a major resection, by sex and cancer network, 2004-2006 followed up to 2007 C67: Bladder The results on this page are a reflection of the surgical treatment data currently available through HES, however, there are limitations in the data available and therefore these results are being presented in order to stimulate further discussions with the clinical community as to what factors affect surgery rates and how we can improve data collection. Differences between cancer networks maybe due to higher rates of private patients, later stage of disease at diagnosis, co-morbidities, miscoding or poor data flow. It is important to read the introduction to this report to understand the limitations of data currently available nationally. These results are observational; there is no "good" or "bad" percentage from these results. Better quality data are required in order to understand how surgery rates can affect outcomes. The cancer network relates to the residence of the patient at diagnosis and not the hospital or trust where the patient was treated. Improved data quality and consistency of coding will allow further research into inequalities in cancer to be undertaken to create a better understanding of how patients are treated within the NHS and to target efforts to improve their outcomes. Major resections by cancer network and sex Male HES linked patients Cancer network N01 Lancashire and South Cumbria CN N02 Greater Manchester and Cheshire CN N03 Merseyside and Cheshire CN N06 Yorkshire CN N07 Humber and Yorkshire Coast CN N08 North Trent CN N11 Pan Birmingham CN N12 Arden CN N20 Mount Vernon CN N21 West London CN N22 North London CN N23 North East London CN N24 South East London CN N25 South West London CN N26 Peninsula CN N27 Dorset CN N28 Avon, Somerset and Wiltshire CN N29 3 Counties CN N30 Thames Valley CN N31 Central South Coast CN N32 Surrey, West Sussex and Hampshire CN N33 Sussex CN N34 Kent and Medway CN N35 Greater Midlands CN N36 North of England CN N37 Anglia CN N38 Essex CN N39 East Midlands CN England 696 1,022 700 900 490 643 541 294 362 403 359 369 374 448 673 362 682 374 690 731 326 398 639 609 1,109 927 493 1,356 16,970 Female 95% Confidence Interval % major resections 10% 10% 8% 12% 6% 12% 10% 10% 11% 12% 11% 7% 10% 12% 6% 6% 12% 15% 15% 12% 12% 13% 13% 11% 9% 12% 11% 10% 11% 8% 9% 6% 10% 4% 10% 8% 7% 8% 10% 8% 5% 7% 9% 4% 4% 10% 12% 13% 10% 9% 10% 11% 9% 7% 10% 9% 8% 10% - HES linked patients 12% 12% 10% 14% 9% 15% 13% 14% 14% 16% 15% 10% 13% 15% 8% 9% 15% 19% 18% 15% 16% 16% 16% 14% 11% 15% 14% 12% 11% 257 433 297 409 185 298 189 103 125 195 122 151 137 181 264 114 233 127 252 270 122 166 212 233 477 322 190 528 6,592 Percentage of NHS treated bladder cancer patients with a record of a major resection, by cancer network 6% 5% 4% 11% 5% 7% 9% 7% 5% 10% 2% 4% 4% 9% 6% 1% 7% 9% 8% 9% 6% 6% 4% 9% 7% 9% 10% 6% 9% - HES linked patients 13% 9% 10% 18% 13% 14% 19% 19% 15% 19% 10% 12% 13% 18% 12% 9% 15% 20% 16% 17% 16% 14% 11% 17% 12% 16% 20% 10% 11% 953 1,455 997 1,309 675 941 730 397 487 598 481 520 511 629 937 476 915 501 942 1,001 448 564 851 842 1,586 1,249 683 1,884 23,562 10 95% Confidence Interval 8% 8% 6% 11% 5% 10% 9% 8% 8% 10% 7% 5% 7% 10% 5% 4% 10% 12% 12% 10% 9% 9% 10% 9% 8% 11% 10% 8% 10% - 12% 11% 9% 15% 9% 14% 13% 14% 13% 16% 12% 9% 12% 15% 8% 8% 14% 18% 17% 15% 15% 14% 14% 14% 10% 14% 15% 11% 11% 1.4 1.2 1.0 0.8 0.6 Networks below 99.8% Confidence limit: N03, N07, N26 & N27 0.2 0 10% 9% 7% 13% 7% 11% 11% 11% 10% 13% 9% 7% 9% 12% 6% 5% 12% 15% 14% 12% 12% 12% 12% 11% 9% 12% 12% 9% 10% Networks above 99.8% Confidence limit: N30 1.6 0.4 Networks below 99.8% Confidence limit: N03, N07, N26 & N27 % major resections Indirectly age-standardised ratio: actual number of NHS treated bladder cancer patients with a record of a major resection divided by the expected number, by cancer network 2.0 Age-Standardised Ratio Percentage of patients 9% 7% 6% 14% 8% 10% 13% 12% 9% 14% 5% 7% 7% 13% 8% 4% 10% 13% 12% 12% 10% 9% 7% 12% 9% 12% 14% 8% 10% Persons 95% Confidence Interval 1.8 Networks above 99.8% Confidence limit: N30 20 % major resections 0.0 0 500 1000 1500 0 2000 Cancer network England average 50 100 150 200 Expected number of patients receiving a major resection Number of HES linked patients cancer network 99.8% confidence limits 99.8% confidence limit The funnel plot of percentages shows that five cancer networks fall outside the 99.8% confidence limits and therefore the difference from the average for England in the percentage of patients recorded as having a major resection is statistically significant for these cancer networks. The plot for the age-standardised ratio shows that when taking into account differences in the age structures of the networks, the same five cancer networks do fall outside the 99.8% confidence limit. We cannot exclude the possibility that poor quality data flowing into HES may account for some of the differences seen. Note: It is important to examine the data for these networks more carefully and investigate further as to what factors may underlie the apparent differences including coding quality within HES. The percentages shown in the table above do not take into account any factors such as differences in the age-distributions, co-morbidities or stage at diagnosis of patients between cancer networks. 35 Glossary Death Certificate Only (DCO) Patients whose diagnosis is solely on the basis of the existence of a death certificate with cancer as a cause of death. Denominator Only patients with at least one linked record within HES were included as the denominator. The number of linked patients is less than the total number of patients diagnosed. As no information is known about patients without a linked HES record, it has been assumed that they were not treated within an NHS hospital for their cancer and therefore are not included in this analysis. 95% confidence intervals For the percentages, 95% confidence intervals are given calculated using the Wilson Score Method. These are a measure of variability in the percentages calculated using the sample size. The upper and lower limits of the confidence interval show how big a contribution chance may have made to a particular statistic. The 95% confidence intervals quoted give the range in which the rate in question would fall 19 times out of 20, were it possible to repeat the analyses. Indirectly age-standardised ratios Age-standardised ratios for cancer networks were calculated using the indirect method. 1 The number of patients recorded with a major resection is divided by the number of patients expected to have received a major resection, given the age distribution of the patients for each network. The expected number is calculated by using the percentages calculated for all patients in England, by age groups, for each site. Percentages by deprivation Weighted ordinary least squares linear regression was used to model the trend across percentages for deprivation quintiles. The weight used for the linear regression was the corresponding number of patients for each quintile. Funnel plots and 99.8% limits Non-age-standardised funnel plots are created to compare the percentage of patients with a record of a major resection for the 28 cancer networks with the overall percentage for England. They show how the networks compare by looking at whether the percentage is above, below or within the 99.8% control limits around the overall percentage for England. The percentages for each cancer network are plotted against the number of HES linked patients within each network to take into account the varying number of patients in each of the cancer networks. 1 Statistical Methods in Cancer Research, Volume IV – Descriptive Epidemiology, IARC Scientific Publications No.128, pp62 36 Only those networks whose percentage lie outside the control limits are highlighted because they appear to have a difference in the percentage with a record of a major resection that is statistically significant. These differences warrant further investigation as the difference may well be affected by data quality issues in HES as well as the linking between cancer registrations and the HES database. Funnel plots for indirectly age-standardised resection ratios show the ratios plotted against the expected number of patients with a record of a major resection (see Indirectly age-standardised ratios). These funnel plots show which networks fall outside the limits once differences in the age structure of the group of patients has been taken into account. Excel sheet templates and explanations of funnel plots are available from the APHO website or from ERPHO 2 It is important to note that the results for each cancer network relates to the postcode of residence of patients and not the cancer network where the patient is treated. SSCRGs The Site Specific Clinical Reference Groups bring together clinical specialists, cancer registries, patient and charity representatives in order to advise, support and shape the work of the NCIN. More information can be found on the NCIN website www.ncin.org.uk OPCS classification Operations and procedures within HES are recorded using the OPCS Classification of Interventions and Procedures. For more information please see www.connectingforhealth.nhs.uk/clinicalcoding Major resection A major resection has been defined with SSCRG lead clinicians as an operation which would be carried out for a cancer patient which would attempt to remove the entire tumour. A list of OPCS-4 codes assigned as major resections for each site are available in Appendix 2. 2 http://www.erpho.org.uk/ViewResource.aspx?id=16120 37 Appendix 1: Percentage of patients linked to at least one record within HES, by site and cancer network, 2004-2006 This table shows the percentage of non-DCO cancer registrations that were linked to HES. Percentages linked for prostate cancer are low due to the relatively high number of patients who are not treated as an inpatient or day case and therefore do not have a record in HES. This table is included to show the proportion of patients that a HES record was available for and included in the analyses for each network. Oesophagus Upper GI Stomach Liver Pancreas Colorectal Lung Breast Gynaecological Cervix Uterus Ovary Prostate Urology Kidney Bladder N01 Lancashire and South Cumbria CN N02 Greater Manchester and Cheshire CN N03 Merseyside and Cheshire CN N06 Yorkshire CN N07 Humber and Yorkshire Coast CN N08 North Trent CN N11 Pan Birmingham CN N12 Arden CN N20 Mount Vernon CN N21 West London CN N22 North West London CN N23 North East London CN N24 South East London CN N25 South West London CN N26 Peninsula CN N27 Dorset CN N28 Avon, Somerset and Wiltshire CN N29 3 Counties CN N30 Thames Valley CN N31 Central South Coast CN N32 Surrey, West Sussex and Hampshire CN N33 Sussex CN N34 Kent and Medway CN N35 Greater Midlands CN N36 North of England CN N37 Anglia CN N38 Essex CN N39 East Midlands CN 98% 96% 97% 96% 99% 98% 98% 97% 97% 95% 94% 95% 95% 96% 97% 99% 97% 95% 95% 95% 94% 96% 93% 95% 98% 98% 97% 99% 95% 96% 94% 96% 96% 98% 96% 96% 92% 91% 93% 93% 93% 92% 94% 97% 96% 94% 92% 92% 93% 95% 93% 95% 97% 94% 96% 97% 91% 94% 91% 86% 89% 93% 92% 94% 84% 88% 90% 91% 88% 87% 93% 93% 90% 96% 88% 88% 80% 89% 83% 88% 90% 91% 87% 94% 91% 94% 92% 92% 93% 97% 98% 95% 83% 92% 87% 92% 88% 88% 93% 95% 92% 94% 89% 93% 87% 90% 87% 89% 94% 92% 91% 96% 96% 95% 94% 95% 96% 96% 95% 95% 92% 93% 91% 94% 93% 92% 95% 95% 96% 95% 91% 94% 92% 92% 90% 94% 97% 94% 95% 97% 95% 93% 91% 90% 93% 96% 94% 94% 88% 91% 88% 91% 90% 88% 93% 94% 92% 92% 88% 90% 88% 90% 87% 90% 92% 92% 93% 96% 95% 91% 89% 88% 88% 91% 90% 89% 79% 84% 83% 88% 85% 84% 92% 89% 88% 90% 82% 89% 81% 86% 83% 90% 93% 88% 85% 91% 93% 94% 92% 89% 86% 90% 91% 90% 85% 91% 90% 90% 90% 86% 95% 89% 84% 82% 89% 91% 92% 84% 76% 94% 83% 83% 94% 90% 93% 93% 92% 88% 93% 96% 91% 91% 81% 89% 93% 92% 85% 83% 94% 92% 95% 90% 87% 92% 86% 90% 88% 92% 93% 90% 93% 94% 93% 93% 88% 88% 91% 93% 91% 88% 86% 89% 88% 92% 86% 91% 94% 96% 94% 92% 87% 95% 85% 86% 89% 91% 92% 91% 94% 93% 89% 76% 78% 70% 74% 86% 80% 66% 68% 67% 72% 74% 64% 60% 83% 63% 83% 65% 60% 65% 65% 72% 60% 61% 78% 75% 62% 82% 95% 94% 91% 92% 95% 94% 92% 95% 89% 91% 88% 93% 91% 87% 95% 92% 91% 89% 87% 94% 94% 93% 90% 90% 96% 93% 93% 94% 97% 96% 97% 95% 99% 97% 97% 98% 95% 94% 95% 96% 96% 93% 97% 96% 97% 95% 94% 96% 94% 93% 95% 95% 97% 96% 96% 98% England 97% 95% 90% 92% 94% 92% 88% 89% 91% 91% 73% 92% 96% 38 Appendix 2: OPCS-4 codes assigned as a major resection by cancer site Oesophagus Code G011 G018 G019 G021 G022 G023 G024 G025 G028 G029 G031 G032 G035 G036 G038 G039 Description Oesophagogastrectomy and anastomosis of oesophagus to stomach Other specified excision of oesophagus and stomach Unspecified excision of oesophagus and stomach Total oesophagectomy and anastomosis of pharynx to stomach Total oesophagectomy and interposition of microvascularly attached jejunum Total oesophagectomy and interposition of jejunum NEC Total oesophagectomy and interposition of microvascularly attached colon Total oesophagectomy and interposition of colon NEC Other specified total excision of oesophagus Unspecified total excision of oesophagus Partial oesophagectomy and end to end anastomosis of oesophagus Partial oesophagectomy and interposition of microvascularly attached jejunum Partial oesophagectomy and interposition of microvascularly attached colon Partial oesophagectomy and interposition of colon NEC Other Specified partial excision Unspecified partial excision Stomach Code G012 G013 G271 G272 G273 G274 G275 G278 G281 G282 G283 G288 Liver Code J021 J022 J023 J024 J026 J027 J028 J029 Description Oesophagogastrectomy and anastomosis of oesophagus to transposed jejunum Oesophagogastrectomy and anastomosis of oesophagus to jejunum NEC Total gastrectomy and excision of surrounding tissue Total gastrectomy and anastomosis of oesophagus to duodenum Total gastrectomy and interposition of jejunum Total gastrectomy and anastomosis of oesophagus to transposed jejunum Total gastrectomy and anastomosis of oesophagus to jejunum NEC Total excision of stomach, Other specified Partial gastrectomy and anastomosis of stomach to duodenum Partial gastrectomy and anastomosis of stomach to transposed jejunum Partial gastrectomy and anastomosis of stomach to jejunum NEC, Billroth II Partial excision of stomach, other specified Description Right hemihepatectomy Left hemihepatectomy Resection of segment(s) of liver Wedge excision of liver Extended right hemihepatectomy Extended left hemihepatectomy Other specified partial excision of liver Partial excision of liver, Unspecified 39 Pancreas Code J551 J552 J558 J559 J561 J562 J563 J564 J568 J569 J571 J572 J573 J574 J575 J578 J579 Description Total pancreatectomy and excision of surrounding tissue Total pancreatectomy NEC Other specified total excision of pancreas Unspecified total excision of pancreas Pancreaticoduodenectomy and excision of surrounding tissue Pancreaticoduodenectomy and resection of antrum of stomach Pancreaticoduodenectomy NEC Subtotal excision of head of pancreas with preservation of duodenum and drainage HFQ Pylorus-preserving Pancreaticoduodenectomy. Excision of head of pancreas, other specified. Excision of head of pancreas, unspecified. Subtotal pancreatectomy Left pancreatectomy and drainage of pancreatic duct Left pancreatectomy NEC Excision of tail of pancreas and drainage of pancreatic duct Excision of tail of pancreas NEC Other specified other partial excision of pancreas Other partial excision of pancreas, unspecified. Pancreatectomy nos Colorectal Code H041 H042 H043 H048 H049 H051 H052 H053 H058 H059 H061 H062 H063 H064 H068 H069 H071 H072 H073 H074 H078 H079 H081 H082 H083 H084 H085 H088 H089 H091 H092 H093 H094 H095 H098 Description Proctocolectomy NEC, Panproctocolectomy and Ileostomy Panproctocolectomy and anastomosis of ileum to anus and creation of pouch HFQ Panproctocolectomy and anastomosis of ileum to anus NEC Other specified total excision of colon and rectum Panproctocolectomy NEC, Total excision of colon and rectum, unspecifiedTotal colectomy and anastomosis of ileum to rectum Total colectomy and ileostomy and creation of rectal fistula HFQ Total colectomy and ileostomy NEC Total excision of colon, other specified Total excision of colon, Unspecified Extended right hemicolectomy and end to end anastomosis Extended right hemicolectomy and anastomosis of ileum to colon Extended right hemicolectomy and anastomosis NEC Extended right hemicolectomy and ileostomy HFQ Other specified extended excision of right hemicolon Extended excision of Right hemicolon, unspecified, excision of Right colon and surrounding tissue Right hemicolectomy and end to end anastomosis of ileum to colon, Ileocaecal resection Right hemicolectomy and side to side anastomosis of ileum to transverse colon, Right hemicolectomy and anastomosis NEC Right hemicolectomy and ileostomy HFQ Other specified other excision of right hemicolon Other excision of right hemicolon, unspecified; Right hemicolectomy NEC Transverse colectomy and end to end anastomosis Transverse colectomy and anastomosis of ileum to colon Transverse colectomy and anastomosis NEC Transverse colectomy and ileostomy HFQ Transverse colectomy and exteriorisation of bowel NEC Other specified excision of transverse colon Excision of transverse colon, unspecified Left hemicolectomy and end to end anastomosis of colon to rectum Left hemicolectomy and end to end anastomosis of colon to colon Left hemicolectomy and anastomosis NEC Left hemicolectomy and ileostomy HFQ Left hemicolectomy and exteriorisation of bowel NEC Excision of left hemicolon, Other specified 40 H099 H101 H102 H103 H104 H105 H108 H109 H111 H112 H113 H114 H115 H118 H119 H291 H292 H293 H294 H298 H299 H331 H332 H333 H334 H335 H336 H337 H338 H339 H404 H408 H409 X141 X142 X143 X148 X149 Left hemicolectmy NEC, Excision of left hemicolon, Unspecified Sigmoid colectomy and end to end anastomosis of ileum to rectum Sigmoid colectomy and anastomosis of colon to rectum Sigmoid colectomy and anastomosis NEC Sigmoid colectomy and ileostomy HFQ Sigmoid colectomy and exteriorisation of bowel NEC Other specified excision of sigmoid colon Unspecified excision of sigmoid colon Colectomy and end to end anastomosis of colon to colon NEC Colectomy and side to side anastomosis of ileum to colon NEC Colectomy and anastomosis NEC Colectomy and ileostomy NEC Colectomy and exteriorisation of bowel Other excision of colon, other specified Hemicolectomy NEC; Colectomy NEC, Other excision of colon, unspecified; Subtotal excision of colon and rectum and creation of colonic pouch and anastomosis of colon to anus Subtotal excision of colon and rectum and creation of colonic pouch NEC Subtotal excision of colon and creation of colonic pouch and anastomosis of colon to rectum Subtotal excision of colon and creation of colonic pouch NEC Subtotal excision of colon, Other specified Subtotal excision of colon, Unspecified Abdominoperineal excision of rectum and end colostomy; APR; SCAPER Proctectomy and anastomosis of colon to anus Anterior resection of rectum and anastomosis of colon to rectum using staples Anterior resection of rectum and anastomosis NEC Hartmann procedure, Rectosigmoidectomy and closure of rectal stump and exteriorisation of bowel Anterior resection of rectum and exteriorisation Perineal resection of rectum HFQ Anterior Resection of Rectum NEC Rectosigmoidectomy NEC, Excision of rectum, unspecified Trans-sphincteric anastomosis of colon to anus Other specified operations on rectum through anal sphincter Unspecified operations on rectum through anal sphincter Total exenteration of pelvis Anterior exenteration of pelvis Posterior exenteration of pelvis Other specified clearance of pelvis Clearance of pelvis, unspecified Lung Code E391 E398 E399 E441 E461 E541 E542 E543 E544 E545 E548 E549 E552 E559 T013 T023 Description Open excision of lesion of trachea Other specified partial excision of trachea Unspecified partial excision of trachea Excision of carina Sleeve resection of bronchus and anastomosis HFQ Total pneumonectomy, total removal of lung, Pneumonectomy NEC Bilobectomy of lung Lobectomy of lung Excision of segment of lung Partial lobectomy of lung NEC Excision of lung, other specified Excision of lung, Unspecified Open excision of lesion of lung Open removal of lesion of lung, unspecified Excision of lesion of chest wall Insertion of prothesis into chest wall NEC 41 Breast Code B271 B272 B273 B274 B275 B276 B278 B279 B281 B282 B283 B284 B285 B286 B288 B289 B341 B342 B343 B352 B353 B374 B401 B408 B409 Description Total mastectomy and excision of both pectoral muscles and part of chest wall Radical mastectomy/total mastectomy and excision of both pectoral muscles NEC. Total mastectomy and excision of pectoralis minor muscle Total mastectomy NEC, inc toilet and simple mastectomy, extended simple mastectomy. Subcutaneous mastectomy Skin sparing mastectomy Total excision of breast other specified. Unspecified, Mastectomy NEC. Quadrantectomy of breast Partial excision of breast, Partial mastectomy, WLE, includes wedge or segmental excision of breast NEC. Excision of lesion of breast, includes lumpectomy, excision biopsy. Re-excision of breast margins Wire guided partial excision of breast Excision of accessory breast tissue Other specified other excision of breast Unspecified other excision of breast Subareolar excision of mammillary duct Excision of mammillary duct NEC Excision of lesion of mammillary duct nec. Microdochectomy. Excision of nipple Extirpation/removal of lesion of nipple. Capsulectomy of breast Interstitial laser destruction of lesion of breast Destruction of lesion of breast, Other specified Destruction of lesion of breast, Unspecified Cervix Code P172 Q011 Q013 Q018 Q071 Q072 Q073 Q074 Q078 Q079 Q081 Q082 Q083 Q088 Q089 X141 X142 X143 Description Excision of Vagina Amputation of Cervix, Radical Trachelectomy Excision of cervix uteri, Lesion of Excision of cervix uteri, Other specified Radical Hysterectomy (removes uterus + cervix + vagina). Wertheims hysterectomy Abdominal Hysterectomy and excision of periuterine tissue NEC.Radical Hysterectomy Abdominal excision of Uterus TAH, Panhysterectomy, hysterectomy NEC (removes uterus + cervix). Total abdominal hysterectomy NEC Other specified abdominal excision of uterus Abdominal excision of Uterus, unspecified Vaginal hysterocolpectomy and excision of periuterine tissue Vaginal hysterectomy and excision of periuterine tissue NEC Vaginal hysterocolpectomy NEC Vaginal excision of Uterus Unspecified vaginal excision of uterus Clearance of Pelvis, total exenteration Clearance of Pelvis, anterior exenteration Clearance of Pelvis, posterior exenteration 42 Ovary Code Q071 Q072 Q073 Q074 Q075 Q078 Q079 Q081 Q082 Q083 Q088 Q089 Q243 Q223 Q235 Q491 Q236 Q438 Q439 Q232 Q241 Q221 Q231 T361 X141 X142 X143 Description Radical Hysterectomy (removes uterus + cervix + vagina). Wertheims hysterectomy Abdominal Hysterectomy and excision of periuterine tissue NEC.Radical Hysterectomy Abdominal excision of Uterus, abdominal hysterocolpectomy nec TAH, Panhysterectomy, hysterectomy NEC (removes uterus + cervix). Total abdominal hysterectomy NEC Abdominal excision of Uterus, subtotal abdominal hysterocolpectomy Abdominal excision of uterus, other specified Abdominal excision of uterus, Unspecified Vaginal excision of uterus, vaginal hysterocolpectomy Vaginal excision of uterus, vaginal hysterectomy Vaginal excision of uterus, vaginal hysterocolpectomy NEC Vaginal excision of uterus, other specified Vaginal excision of Uterus, Unspecified Oophorectomy NEC Bilateral oophorectomy, excision of gonads Unilateral oophorectomy NEC Endoscopic extirpation of lesion of ovary NEC Oophorectomy of remaining solitary ovary NEC Other specified partial excision of ovary Unspecified partial excision of ovary Salpingoophorectomy of remaining solitary fallopian tube and ovary Salpingoophorectomy NEC Bilateral salpingoophorectomy Unilateral salpingoophorectomy NEC Omentectomy Clearance of Pelvis, total exenteration Clearance of Pelvis, Anterior exenteration Clearance of Pelvis, Posterior exenteration Uterus Code Q071 Q072 Q073 Q074 Q079 Q081 Q082 Q083 Q088 Q089 Q078 Q075 Q093 Q161 Q229 Q239 Q521 X141 X142 X143 Description Radical Hysterectomy (removes uterus + cervix + vagina). Wertheims hysterectomy Abdominal Hysterectomy and excision of periuterine tissue NEC.Radical Hysterectomy Abdominal hysterocolpectomy NEC, Hysterocolpectomy NEC TAH, Panhysterectomy, hysterectomy NEC (removes uterus + cervix). Total abdominal hysterectomy NEC Abdonimal excision of uterus, unspecified Vaginal hysterocolpectomy and excision of periuterine tissue Vaginal hysterectomy and excision of periuterine tissue NEC Vaginal hysterocolpectomy NEC Vaginal Excision of Uterus, other specified Unspecified vaginal excision of uterus Other specified abdominal excision of uterus Subtotal abdominal Hysterectomy (does not remove cervix) Open excision of lesion of uterus NEC Other vaginal operations on uterus, vaginal excision of lesion of uterus Bilateral Excision of adnexa of uterus unspecified Unspecified unilateral excision of adnexa of uterus Excision of lesion of broad ligament of uterus Clearance of pelvis, Total exenteration Clearance of pelvis, Anterior exenteration Clearance of pelvis, Posterior exenteration 43 Prostate Code M611 M614 M618 M619 Description Total / Radical prostatectomy, Total excision of prostate and capsule Perineal prostatectomy Open excision of prostate, other specified Prostatectomy NEC. Open excision of prostate, unspecified Bladder Code M341 M342 M343 M348 M349 Description Cystoprostatectomy Cystourethrectomy Cystectomy NEC Other specified total excision of bladder Unspecified total excision of bladder Kidney Code M021 M022 M023 M024 M025 M028 M029 M038 M039 M042 M104 M181 M182 M183 M252 Description Nephrectomy and excision of perirenal tissue, Nephroureterectomy and excision of perirenal tissue Nephroureterectomy NEC Bilateral nephrectomy Excision of half of horseshoe kidney Nephrectomy NEC Total excision of kidney, other specified Total excision of kidney, unspecified Other specified partial excision of kidney Partial nephrectomy NEC, Partial excision of kidney, Unspecified Open excision of lesion of kidney NEC Endoscopic cryoablation of lesion of kidney Total ureterectomy , Ureterectomy NEC Excision of segment of ureter Secondary ureterectomy Open excision of lesion of ureter NEC 44 March 2011 The National Cancer Intelligence Network is a UK-wide initiative, working to drive improvements in standards of cancer care and clinical outcomes by improving and using the information collected about cancer patients for analysis, publication and research. To find out more about NCIN or to read our other publications, please visit our website www.ncin.org.uk National Cancer Intelligence Network Coordinating Centre 18th Floor, Portland House Bressenden Place London, SW1E 5RS Tel: +44 (0) 20 8282 6258 Fax: +44 (0) 20 7869 8191 [email protected] national cancer intelligence network
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