INTERNATIONAL BULLETIN O F BACTERIOLOGICAL NOMENCLATURE AND TAXONOMY Volume 6 No. 1 January 15, 1956 pp. 13-17 NOMENCLATURAL SIGNIFICANCE O F -IASIS, -OSIS, AND -1TIS AS SUFFIXES IN NAMING DISEASES R . E. Buchanan -*, The Greeks named many d i s e a s e s , frequently by u s e of t h r e e suffixes, - i a s i s , and.-+, added to suitable s t e m s of v e r b s o r nouns. These Greek precedents have commonly been followed to the p r e s e n t in the nomenclature of d i s e a s e . F u r t h e r m o r e , there a r e , i n the l i t e r a t u r e of microbiology, numerous examples of names of microorgani s m s (particularly specific epithets) derived f r o m the name of the related d i s e a s e . Some uncertainty has been e x p r e s s e d a s to the formation of the genitives of words formed by the use of the t h r e e suffixes due to the fact that each has the ending -&in the nominative; the f i r s t two have a s the genitive - i a s i s and -6sis, respectively ( s a m e a s the nominative), but the third i z has as the genitive -itidis. One finds Mycobacterium tuberculosis, but Salmonella enteritidis. A brief review of the origin, meanings, and u s e s of these suffixes s e e m s desirable. - The Greek Suffix - L ~ O - L= ~ -iasis Buck and P e t e r s e n , i n their "Reverse Index of Greek Nouns and Adjectives" l i s t about 4350 Greek words with the c c g = -sis. Almost a l l a r e feminine nouns. termination = - i a s i s . The Of these about 130 h a z the ending - L a a r c Greeks derived these nouns frequently f r o m v e r b s having the meaning "to suffer f r o m a d i s e a s e . " Some examples may be given. - = lithia6 to suffer f r o m the stone; = lithiasis the d i s e a s e of the stone ( u r i n a r y calculus ) ~ U U O U ~ L & W= dysuria6 to have retention of urine; 8uuoup;aorc = d y s u r i a s i s dysuria & h E T a v ' t L & w = elephantia; to suffer f r o m elephantiasis. 6 %E ya V T 4 a c r r g = elephantiasis. AcQr&w ht0iabrg . Downloaded from www.microbiologyresearch.org by IP: 88.99.165.207 On: Sat, 17 Jun 2017 07:01:06 P a g e 14 INTERNATIONAL BULLETIN D T r a n s l i t e r a t i o n of s o m e o t h e r s of the G r e e k names of d i s e a s e s will show the c h a r a c t e r of this u s e . c r i t h i a s i s a mange of the h o r s e . alopeciasis fox mange. t h r i c i a s i s a shivering. h e l i a s i s sunstroke bulimiasis suffering f r o m ravenous hunger. scotodiniasis dizziness, vertigo. nyctalopiasis night blindness. hydropiasis dropsy. m y d r i a s i s enlargement of the pupil of the eye. h y d e r i a s i s dropsy. s c l e r i a s i s a n induration of the eyelid. p h t h i r i a s i s lousiness, pediculosis. siriasis s u n s t r o k e . s t e n o c o r i a s i s contraction of the pupil of the e y e . satyriasis satyriasis, priapism. pityriasis scurf. o c h r i a s i s a turning pale, p a l e n e s s . p o r i a s i s a c a l l u s on the eye. p s o r i a s i s itch o r s c a b . n a u s i a s i s qualmishness. c e l e phia s i s l e p r o s y gomphiasis toochache. . . In general, i t is c l e a r that when used a s a n ending f o r the name of a d i s e a s e - i a s i s m e a n s "a d i s e a s e c h a r a c t e r i z e d by the p r e s e n c e of. The diagnostic f e a t u r e may be the symptoms of t h e d i s e a s e (alopeciasis, t h r i c i a s i s ) , the p a r a s i t e p r e s e n t ( p h t h i r i a s i s ) , a lesion of pathological change c h a r a c t e r i s t i c of the d i s e a s e ( p o r i a s i s ) . Appropriately the suffix - i a s i s is added to G r e e k s t e m s . Many names of d i s e a s e s have been f o r m e d by adding this ending to the s t e m of the generic name of the c a u s a l organi s m . However, s u c h n a m e s may be of Latin origin. T h e r e is now ample precedent for naming d i s e a s e s by u s e of - i a s i s with Latin o r m o d e r n L a t i n s t e m s , a s f i l a r i a s i s f r o m f i l a r i a . Names of d i s e a s e s ending in - i a s i s when u s e d i n specific epithets a r e feminine nouns, to be placed i n the genitive. They a r e i n the t h i r d declension. Downloaded from www.microbiologyresearch.org by IP: 88.99.165.207 On: Sat, 17 Jun 2017 07:01:06 Page 15 BACTERIOLOGICAL NOMENCLATURE AND TAXONOMY When transliterated into Latin form, these names a r e placed in the corresponding Latin declension, a s psoriasis, -is. The genitive and nominative forms a r e the same. S h o s d one describe a new species of Mycobacterium associated with leprosy, i t might appropriately be termed Mycobacterium celephiasis (the Mycobacterium of leprosy). - The Greek suffix - WCrcq - = -&is. About 900 of the Greek words which end in - g s (more than 4300 in all) have the termination - W D t g = -6sis. They a r e feminine nouns. Here again, the Greeks s o m x m e s derived these nouns from verbs having some connotation relating to disease. A s examples: auptyy6 0 = syringob to grow hollow, to end in a fistula; , ‘ E 3 C = syringosis, -is, - the formation of a fistula. - oupcyygutc X a A c c C & w = chalaza6 to have pimples o r tubercles; -Xahcctwat5, . w e = chalazosis. -is tuberculousness. - -1 - E; e tuberculosis ? v apx&w = narca6 to become numb; = narcosis, -is, a benumbing. - v ’ a ‘ p x o a t ~, - Other transliterations of similar Greek names of disease will illustrate . thrombosis a becoming curdled. phalangosis ingrowing eyelashes. phlogosis burning heat, inflammation. rhytidosis a wrinkling , contraction. lithosis hardening, a turning to stone. peliosis a livid spot. heliosis exposure to sun. poliosis a becoming gray theriosis a turning into a beast. stranguriosis strangury, difficulty in urination. nausiosis a vomiting. rhacosis a becoming wrinkled. anthracosis a malignant ulcer (eye). Downloaded from www.microbiologyresearch.org by IP: 88.99.165.207 On: Sat, 17 Jun 2017 07:01:06 P a g e 16 INTERNATIONAL BULLETIN leucosis a white spot ( c a t a r a c t ) in the eye. glaucosis blindness f r o m glaucoma. s y r c o s i s u l c e r (like over-ripe f i g ) of the eyelid. When used a s an ending f o r the name of an a b n o r m a l i t y o r disease, - 6 s i s means ?'characterized by the p r e s e n c e of, I ' not d i f f e r i n g e s s e n t i a l l y in meaning f r o m that given by the suffix - i a s i s . In fact, the Greeks in a few c a s e s used both endings. The something p r e s e n t may be a symptom, a l e sion, an associated p a r a s i t e , o r some other c h a r a c t e r i s t i c . While m o r e appropriately added to the s t e m s of Greek has frequently been used i n the f o r words, the ending mation of names of d i s e a s e s by addition to Latin or modern Latin s t e m s , a s i n tuberculosis, brucellosis, l i s t e r i o s i s , and s a r c i n o s i s . The Latin genitive of the name of a disease ends ( a s the nominative) in -=s, as in Mycobacterium tuberculosis (the Mvcobacterium of tuberculosis 1. -* The Greek Suffix -t 't L 5 = -* In the Greek t h e r e a r e about 2400 words (nouns and ad- r 6 0 C = -is, - -idis. Of jectives) having the ending these about 300 have the ending - ~ T C ,C - c T c G o ~ = - i t i s , -itidis. Many of these a r e feminine adjectives. Among these a r e some derived f r o m the names of p a r t s of the body, and used to modify the feminine noun v 6 u o C = nosus sickne8s or disease. F o r example, V . ~ Q O ~V E ~ P ? ' C L C = nosus nephritis, diseaee of the kidneys, f r o m v ~ c p p b ~= nephrus kidney. Generally, in r e f e r r i n g to diseases the noun nosus was omitted, and the adjective was t r e a t e d a s a noun and a s the name of the disease. A s stated by Buck and P e t e r s e n : -5, - - - - - -=, "An excursive group of this type consists of names of diseases in productive in international medical nomenclature even a t the p r e s e n t t i m e . " A s stated in Dorland's Medical Dictionary: "The feminine form, -itis, i s so often associated with inflammatory disease, that i t has acquired i n m o s t c a s e s the significance of inflammation. I t Downloaded from www.microbiologyresearch.org by IP: 88.99.165.207 On: Sat, 17 Jun 2017 07:01:06 P a g e 17 BACTERIOLOGICAL NOMENCLATURE A N D TAXONOMY Some examples f r o m the Greek: yp<v ~ = p h r e n mind; - E V T, -T 1605 ~ ~ = p h r e n i t i s , -itidis inflammation of the brain, phrenitis ~ . &,p@pov = a r t h r u m a joint; u p 8 p T T t S , - L 6 0 g- = a r t h r i t i s , -itidis gout, a r t h r i t i s . - 6; u p , -- f i n g ~ o= ~ h e p a r , hepatis the l i v e r ; 7 7~ aT ;T LC , - 4 6 0 s = hepatitis, -itidis of o r i n the liver, hepatitis. - Among the many other names of d i s e a s e s taken d i r e c t l y f r o m s i m i l a r G r e e k adjectives a r e : sphagitis, -it i d i s s o r e t h r o a t . s y r i n g i t i s , i t i d i s inflammation of the Eustachean tube. splenitis, itidis inflammation of the spl,een. blepharitis, itidis inflammation of the eylids p l e u r i t i s , itidis p l e u r i s y . nephritis, itidis n e p h r i t i s . . In forming n a m e s of d i s e a s e s f r o m n a m e s of o r g a n s o r t i s s u e s , the ending - E s h a s come to be added not only to Greek s t e m s (as i n g a s t r i t i s , s t o m a t i t i s ) but to Latin s t e m s as well (appendicitis, s i n u s i t i s , gingivitis). Names of d i s e a s e s i n m o d e r n Latin ending in - x s a r e feminine nouns and have a s the genitive ending - i t i d i s . SUMMARY Names of d i s e a s e s with the suffix - i a s i s a r e m o d e r n Latin feminine nouns with the genitive ending a l s o - i a s i s . Those with the suffix - 6 s i s a r e a l s o modern Latin f e m i nine nouns with the genitive ending - 0 2 . Those with the suffix -itis a r e modern Latin feminine nouns with the genitive ending -itidis. These endings, while m o r e c o r r e c t l y u s e d with G r e e k s t e m s , a r e commonly added a l s o to Latin and to modern Latin s t e m s . Downloaded from www.microbiologyresearch.org by IP: 88.99.165.207 On: Sat, 17 Jun 2017 07:01:06 Downloaded from www.microbiologyresearch.org by IP: 88.99.165.207 On: Sat, 17 Jun 2017 07:01:06
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