Technical Information
Bronidox® L
July 2013
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WF-No. 2063
® = Eingetragene Marke der BASF
For use as preservative of cosmetic preparations (only for rinse-off formulations).
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CAS name
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Bronidox® L
5-Bromo-5-nitro-1,3-dioxane
PRD-No.*30528591
* BASF’s commercial product number.
Synonyms
5-Bromo-5-nitro-m-dioxane
5-Bromo-5-nitro-1,3-dioxane (INCI)
Structural Formula
Br
O 2N
O
O
Molecular formulaC4H6BrNO4
Molar Mass
212.00 g/mol
CAS-No.30007-47-7
EINECS-No.250-001-7
Product composition
10% 5-Bromo-5-nitro-1,3-dioxane in 1,2-propylene glycol
08_130702e-00 July 2013
Description
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Bronidox® L
Almost colorless, transparent liquid
Odor
slightly alcohol inherent odor
Active matter
9.5 – 10.5%
Refractive index
(20 °C)
1.435 – 1.437
Density at 20 °C
1.08 – 1.09 g/cm3
Cloud point
<15 °C
Water content
≤0.5%
pH value
(10% (m))
3 – 3.5
Flash point
99 – 100 °C
Boiling point
190 °C
This information does not necessarily form part of the product specification. A detailed
specification is available from your local BASF sales office.
Solubility and Miscibility
Ethylether
Ethylalcohol
Paraffinoil
Water
Storage Stability If stored in the original, unopened containers, in dry conditions and between
20 – 30 °C, Bronidox® L has a shelf life of 12 months. Storage or transportation
at cold temperature might result in crystallization and reduced activity caused
by crystal separations at the bottom. Such precipitations can be dissolved by
heating up the material to a maximum of 40 °C while stirring.
very soluble
very soluble
practically insoluble
sparingly soluble (0.5% a.i.)
Bronidox® L might be corrosive on metal materials; thus application in aerosol
products or unprotected metal containers cannot be recommended.
Bronidox® L is temperature stable up to 40 °C and not subject to changes when
applied in surfactant preparations in the pH range of 5 – 8.
Trace Metal Content Analysis of BASF Bronidox® L shows that the trace metal content is less than 10 ppm
in the product.
Antimicrobial Activity Bronidox® L has a broad spectrum activity against bacteria and fungi. Due to its
good compatibility with other cosmetic raw materials it can be also combined with
other preservatives.
In accordance with the Cosmetic Products Regulation ((EC)1223/2009), the conditions
of use for 5-Bromo-5-nitro-1,3-dioxane are listed in Annex V (reference number 20).
It is approved to a maximum concentration of 0.1% for use in rinse-off products
only and the formation of nitrosamines must be avoided.
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MIC values for Bronidox® L
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Bronidox® L
The Minimum Inhibitory Concentrations (MIC) for Bronidox® L against a range of test
organisms is shown below (Wallhäußers Praxis der Sterilisation, Desinfektion,
Antiseptik und Konservierung; published by Thieme Germany., 1st edition, 2008).
Gram positive bacteria
Gram negative bacteria
Yeasts
Moulds
Organism
ppm a.i.
Streptococcus faecalis
30 – 75
Staphylococcus epidermidis
50
Staphylococcus aureus
75
Escherichia coli
50
Serratia marcescens
25
Candida albicans
25 – 75
Saccharomyces cerevisiae
10 – 65
Aspergillus niger
10 – 250
Application
BASF Bronidox® L can be used in a wide range of cosmetic rinse-off formulations.
Registration and Approvals Detailed information on regional registration and approval status are available on
request.
Safety
For detailed information see MSDS.
Safety Notes According to the experience gained over many years and to other information
at our disposal, Bronidox® L should not exert any harmful effects on health. This
is provided that they are used properly, that due attention is given to the safety
and industrial hygiene precautions necessary for handling chemicals and that the
information and advice given on our Safety Data Sheets are observed.
Handling and Storage Contact with eyes and skin should be avoided. Safety goggles must be worn when
handling the concentrated product. The product should be stored in sealed containers
as supplied, in dry conditions at temperatures not exceeding 40 °C.
Recommended storage temperature: 20 – 30 °C.
Labelling
Please refer to the latest Safety Data Sheet for detailed information on product safety.
Classification according to UN criteria
see MSDS
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Contacts Europe
BASF SE
Care Chemicals & Formulators Europe
Carl-Bosch-Straße 38, 67056 Ludwigshafen, Germany
Phone:+49 (621) 60-0
Fax:+49 (621) 60-42525
e-mail:[email protected]
[email protected]
www.care-chemicals.basf.com
BASF Grenzach GmbH
Köchlingstraße 1, 79639 Grenzach-Wyhlen, Germany
Phone:+49 (7624) 12 2892
Fax:+49 (7624) 12 2888
www.basf.com
North America
BASF Corporation
Florham Park, NJ 07932, USA
US and Canada
Phone: +1(800) 880 5768
Fax: +1(973) 245 6764
Mexico
Phone: +1(800) 723 3000
Fax: +1(800) 552 4288
e-mail:[email protected]
www.personal-care.basf.com
Bronidox® L
South America
BASF S.A.
04538-132 São Paulo, Brazil
Phone:+55 (11) 3043 2284
Fax:+55 (11) 3043 2255
e-mail:[email protected]
www.personal-care.basf.com
Asia
BASF East Asia
Regional Headquarters Ltd., Central, Hong Kong, China
Phone: +85 2731 0190
Fax: +852 2731 5639
e-mail:[email protected]
www.personal-care.basf.com
Note
This document, or any answers or information provided herein by BASF, does
not constitute a legally binding obligation of BASF. While the descriptions, designs,
data and information contained herein are presented in good faith and believed
to be accurate, it is provided for your guidance only. Because many factors may
affect processing or application/use, we recommend that you make tests to
determine the suitability of a product for your particular purpose prior to use. It
does not relieve our customers from the obligation to perform a full inspection of
the products upon delivery or any other obligation. NO WARRANTIES OF ANY KIND,
EITHER EXPRESS OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY
OR FITNESS FOR A PARTICULAR PURPOSE, ARE MADE REGARDING PRODUCTS
DESCRIBED OR DESIGNS, DATA OR INFORMATION SET FORTH, OR THAT THE
PRODUCTS, DESIGNS, DATA OR INFORMATION MAY BE USED WITHOUT
INFRINGING THE INTELLECTUAL PROPERTY RIGHTS OF OTHERS. IN NO CASE
SHALL THE DESCRIPTIONS, INFORMATION, DATA OR DESIGNS PROVIDED BE
CONSIDERED A PART OF OUR TERMS AND CONDITIONS OF SALE.
July 2013
BASF - Care Chemicals Division - www.formulation-technologies.basf.com