Date of Issue: 12/2014
Page 1 of 3
Zinc Bromide / Lithium Bromide, 25 % solution in
Dibutyl Ether
PRODUCT
Zinc Bromide / Lithium Bromide, 25 % solution in Dibutyl Ether
Product No. 408605
CAS-No. 7699-45-8
FURTHER
INGREDIENTS
APPLICATION
EINECS-No. 231-718-4
LiBr
CAS-No. 7550-35-8 EINECS-No. 231-439-8
Dibutyl Ether
CAS-No. 142-96-1 EINECS-No. 205-575-3
The use of a 'ready-made' dibutyl ether solution avoids the handling of the very hygroscopic
and dusty ZnBr2 and LiBr powder.
The ZnBr2 /LiBr dibutyl ether solution was developed mainly for the application in organic
synthesis, e.g.:
- transmetallation of organomagnesium and organolithium compounds to the corresponding
zinc reagents for C-C coupling reactions (Negishi protocol)
- formation of zinc enolates by deprotonation of carbonyl compounds using standard bases
followed by transmetallation with ZnBr2
- catalysis of cycloaddition reactions e.g. Diels-Alder reactions of electron rich dienes with
carbonyl compounds
- preparation of selective reducing agents, e.g. Zn(BH 4 )2 by reaction of NaBH 4 with ZnBr2
Reference:
McGarvey, G.J. in Encyclopedia of Reagents for Organic Synthesis, Paquette, L.A., Ed. John
Wiley and Sons, New York (1995), Vol. 8, 5544
APPEARANCE
yellow-brownish to pink, clear to slightly turbid solution
FORMULA
Br3 LiZn
The abov e details hav e been compiled to the best of our knowledge
on the basis of thorough tests and with regard to the current state
of our long practical experience. No liabilities or guarantees deriv ing
f rom or in connection with this leaf let can be imputed to us.
Reproduction, in whole or in part, only with our express permission.
® registrated trademark
www.rockwoodlithium.com
Europe:
Rockwood Lithium GmbH
Fax: +49 69 40126-72000
Americas:
Rockwood Lithium Inc.
Fax: +1 704 734-2718
Asia:
Rockwood Lithium Japan K.K.
Fax: +81-3-6434-5623
Product No. 408605
Date of Issue: 12/2014
Page 2 of 3
PHYSICAL
PROPERTIES
SPECIFICATION
Molecular weight:
225.19 g/mol (ZnBr2 )
Density:
1.1
Boiling Point:
140 - 143 °C (Dibutyl Ether at 1,013 hPa)
Flash Point:
25 °C (Dibutyl Ether)
Thermal Stability:
Crystallization below -10 °C
Zinc Bromide
23 - 27 %
Lithium Bromide
8 - 12 %
Water content
< 0.13 %
METHOD OF
ANALYSIS
Determination of assay by complexometric titration of zinc, determination of lithium by FES
and determination of water by Karl-Fischer titration, bromide calculated.
HANDLING
Under exclusion of air and humidity stable over practically unlimited periods. Dibutyl ether
can form explosive peroxides in contact with air. Storage and handling under inert gas is
recommended. Pay attention to official safety regulations (see also 'Transport regulations'
and 'GHS Hazard Pictograms').
TRANSPORT
REGULATIONS
UN-No.:
2924
Rail/Road (RID/ADR):
Class 3
PG III
Label 3 (8)
Sea (IMDG-Code):
Class 3
PG III
Label 3 (8)
Air (IATA-DGR):
Class 3
PG III
PAX 354
CAO 365
Mail:
forbidden
GHS HAZARD
PICTOGRAMS
H&P Phrases: See Safety Data Sheet
SIGNAL WORD
Danger
PACKING
Glass bottles of 100, 250, 500, and 1,000 ml. Steel bottles with volumes of 7.4, 27, 127 or
450 l. Steel drums up to 200 l. For safety reasons these are filled to a maximum of 90 %.
TIME OF DELIVERY
Upon request
The abov e details hav e been compiled to the best of our knowledge
on the basis of thorough tests and with regard to the current state
of our long practical experience. No liabilities or guarantees deriv ing
f rom or in connection with this leaf let can be imputed to us.
Reproduction, in whole or in part, only with our express permission.
® registrated trademark
www.rockwoodlithium.com
Europe:
Rockwood Lithium GmbH
Fax: +49 69 40126-72000
Americas:
Rockwood Lithium Inc.
Fax: +1 704 734-2718
Asia:
Rockwood Lithium Japan K.K.
Fax: +81-3-6434-5623
Product No. 408605
Date of Issue: 12/2014
Page 3 of 3
FURTHER RELATED
DOCUMENTS
Flyer 'Water-free Salts in Organic Synthesis', Safety Data Sheet
The abov e details hav e been compiled to the best of our knowledge
on the basis of thorough tests and with regard to the current state
of our long practical experience. No liabilities or guarantees deriv ing
f rom or in connection with this leaf let can be imputed to us.
Reproduction, in whole or in part, only with our express permission.
® registrated trademark
www.rockwoodlithium.com
Europe:
Rockwood Lithium GmbH
Fax: +49 69 40126-72000
Americas:
Rockwood Lithium Inc.
Fax: +1 704 734-2718
Asia:
Rockwood Lithium Japan K.K.
Fax: +81-3-6434-5623