Practical aspects of the use of intrathecal chemotherapy








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

      




        

      
       



        
    
          
      
       



       







  


 


        




      
       












          
          




         
    
        

































        
       
       
        

     
         
  
        
       


       





          
      

       
        

     
      


   



       

     
 
  
    


      
       
     
   




   









































       


      


     

     

     

   




    


       





       
      



   




        

           

     

      
        
   



   

      
         





       

      
     


      
        


    
   






         
       

      
       


      

     



       

    




        








        
      




    

           

     
        
        
      
       

      

       
         
       
       
        
      





       


        



       
       
        
     
      
     

      

      


       



      
     

         
     

      
      




      
        
         

          

      


         
       


      
      
          




        




      
      
       

      

        
         






       
  





     
     
















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
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










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














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














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







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

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






  


      

        

        
       
       




       

       










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
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

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














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












      


        
      




       
        
    
    
      
     




       

 
      
      
       
      








        


    





        

       

       
    
     


      

       


  


       
       


     
          


     

       
  
        

     

          
      



      

       
      

   



        
         
        
    

        
          



   
        
       
     

     






        

         

         
       





            
     







   
 

       
     
      
       


 

      



        



    



     

       

       

      
       

    

    
       







       
       

     
        

      
      
     


      
       

      

         


   
         

       


       



 
      
      
         



       


      
        

      
     
    





       



     

         



    




      



      
         

           


        
       



      

      





       


       

       





       
     


         


       
       
 

        
     




       

         
      
         
      
      

        



     









 

        
    



      
  






       
  
       


       






















































































































































 











    
       
       




        

      



    




 

        
  

          
       
         



     









      

       


     
 
       



    

  

         


          



       
     
    


       



 
    


       

         

        
       



     
    
     

       



         
      
       


        





















 










































 


 
     


       
   



           

        

 

       



 

   

 
       
    


 
       

 


 

       

              
        
         

 

           
         
      

         
         
    


 
       

 
       


 


    
      
        

 
 




      


         
       

         


         
         


       
       

        
      

          
       

 

        
           

 



        
      

 



 




             


        

           
        
        
     

 
         

      
      

 


 


 
       

 

 



             
     
        

           
      

 







 


 




        
      

 

    

 



 



         
       
     


 



 
        




 



     
         
       


 


 



 

   


 

        



        


 
         


 

     

 



 



 


            
       



          




       
        
       
    




       
       

 
       

 

         
       

 


      
        
     
        

 

        

          
         
       
      
         

 



 


 
       


 


          
          




 



           
         

        



 




       

      


         
        

 


 


 

 

 



       
         
         
        


       
      


         
     

























      
         

        
       





























      

       


 



      
      




        

        
        
    
        















     





       
      

      








    


      










         
        
        

       
        















        
       
      
        
         



      






      

      



       
       




        






       
     


         
      
         
    
        



     



      









        









      
 





        
        

      






     



       
     

   
      
     






      
      
       








      
     
        



       

    





        



       









      



         


           



       
        




















































































 








     
        
      
      
       
       
       
         
      

        

   

         


         







       
     


      
        
       


      



       







         

       






       

        
    
       
         

















































        
       
        
    



     
       


       


      
        
      

         
     
        


        



        







     
        
  



     

          


        


       



     


     




    








   
     
      
             

       

         


        




          






      
        
      






       








  
       


        




       
    
       







       

   



        
      
        




   
     










       

     
       

         
        

         



        

       
          



         
      
        








     
        
     
       
        
        



       

         
      

       




        
       


       
      



       




        









         


      


      
      







       
    




 

       







         



        




        

         
      









     

         

     




        
     
        

           

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



       
   





       
      






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




   


         

 
















 
















































































































































     
       
        
          
      
      



      
      
       
       

        




      
        
        






  
         















 


































     
        
         
        
       




       





      
       



        

       

















 


 
     


 
   


                                              
 
           

        

 

       



 

   


 
       
    


 
       

 


 

       

              
        
         

 

           
         
      

         
         
    


 
       

 
       

 


    
      
        

 
 




      


         
       

         


         
         


       
       

        
      


          
       

 

        
           

 



        
      

 



 




             


        

           
        
        
     

 
         
      
      

 



       


 
       

 

 



             
     
        

           
      

 








 


 




        
      

 

    

 



      
       
 


         
       
     


 



 
        



 



     
         
       


 


 



        
          
       

      

 

        




        


 


 

     

 



 



 


            
       



          




       
        
       
    


       
       

 
       

 

         
       

 


      
        
     
        

 

        

          
         
       
      
         


 



 


 
       


 


          
          




 



           
         

        




 




       

      


 

 


 


 

 

 



       
         
         
        
