MATERIAL SAFETY DATA SHEET
1. SUBSTANCE AND SOURCE IDENTIFICATION
National Institute of Standards and Technology
Standard Reference Materials Program
100 Bureau Drive, Stop 2300
Gaithersburg, Maryland 20899-2300
SRM Number: 699
MSDS Number: 699
SRM Name: Alumina (Reduction Grade)
Date of Issue: 30 August 2011
MSDS Coordinator: Mario Cellarosi
Telephone: 301-975-2200
FAX: 301-926-4751
E-mail: [email protected]
Emergency Telephone ChemTrec:
1-800-424-9300 (North America)
+1-703-527-3887 (International)
Description: This Standard Reference Material (SRM) is intended for use in the evaluation of chemical methods of
analysis and in calibration of instrumental analyses. Each unit of SRM 699 consists of 60 g alumina powder of
which 95 % passes a 74 µm (No. 200) sieve.
Substance: Alumina
Other Designations:
Alundum, aluminum oxide, aluminum trioxide
2. HAZARDS IDENTIFICATION
NFPA Ratings (Scale 0–4):
Health = 1
Fire = 0
Reactivity = 0
Major Health Hazards: Alumina can cause respiratory tract irritation, skin and eye irritation.
Physical Hazards: There are no known physical hazards associated with this material.
Potential Health Effects
Inhalation: Inhalation of high concentrations may cause coughing, shortness of breath, respiratory tract
irritation due to mechanical action, unpleasant deposits in the nasal passages, and exacerbation of symptoms in
persons with impaired pulmonary function.
Skin Contact: Contact may cause an irritant dermatitis accompanied by pruritis.
Eye Contact: Dust may cause mechanical irritation with redness and possibly swelling of the conjunctiva.
Ingestion: Chronic ingestion of aluminum compounds cause constipation.
Medical Conditions Aggravated by Exposure: This material may aggravate respiratory disorders.
Listed as a Carcinogen/Potential Carcinogen
Component: Alumina
In the National Toxicology Program (NTP) Report on Carcinogens
In the International Agency for Research on Cancer (IARC) Monographs
By the Occupational Safety and Health Administration (OSHA)
Yes
No
X
X
X
3. COMPOSITION AND INFORMATION ON HAZARDOUS INGREDIENTS
Component
Aluminum Oxide
CAS Number
EC Number
(EINECS)
1344-28-1
215-691-6
Nominal Mass Concentration(a)
(%)
>99
(a)
The material’s maximum particle size is below the inhalation size limits (100 µm or 100 microns, inhalation) established by
the ACGIH, Appendix D. This material contains inorganic compounds (See Certificate of Analysis), including trace amounts of
quartz, which have been reported to have toxic, mutagenic, and/or carcinogenic properties, and should be handled with care. The
concentration of these compounds are below the reportable limit for hazardous components (1 %) and carcinogens (0.1 %), as
required by OSHA, 29 CFR 1910.1200 (g)(2)(i)(C)(1), for MSDS information.
MSDS 699
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Component: Aluminum Oxide
EC Classification:
Not classified.
EC Risk (R No.):
Not assigned.
EC Safety (S No.):
Not assigned.
EC Classification Risk/Safety Phrases: Refer to Section 15, “Regulatory Information”.
4. FIRST AID MEASURES
Inhalation: If adverse effects occur, remove to uncontaminated area. If not breathing, give artificial respiration or
oxygen by qualified personnel. Seek immediate medical attention.
Skin Contact: Rinse affected area with copious amounts of water followed by washing with soap and water for at
least 15 minutes while removing contaminated clothing. Seek medical attention, if needed.
Eye Contact: Immediately flush eyes, including under the eyelids with copious amounts of water for at least
30 minutes. Seek immediate medical attention.
Ingestion: Contact a poison control center immediately for instructions. Seek immediate medical attention.
5. FIRE FIGHTING MEASURES
Fire and Explosion Hazards: Negligible fire hazard.
Extinguishing Media: Use extinguishing media appropriate to the surrounding fire.
Fire Fighting: Avoid inhalation of material or combustion by-products.
NIOSH-approved self-contained breathing apparatus (SCBA).
Wear full protective clothing and
Flash Point: Not applicable.
Autoignition Temp.: Not applicable.
Flammability Limits in Air
Upper Explosive Limits (UEL): Not applicable.
Lower Explosive Limits (LEL): Not applicable.
Products of Combustion: Thermal decomposition may release hazardous or toxic gases (see “Section 10. Stability
and Reactivity”).
6. ACCIDENTAL RELEASE MEASURES
Occupational Release: Do not touch spilled material. Notify safety personnel of spills. Place in suitable container
for proper disposal. Avoid generating dust. Clean up residue with a high-efficiency filter vacuum.
Disposal: Refer to Section 13, “Disposal Considerations”.
7. HANDLING AND STORAGE
Storage: Store and handle in accordance with all current regulations and standards.
incompatible substances. Use methods to minimize dust.
Keep separated from
Safe Handling Precautions: See Section 8, “Exposure Controls and Personal Protection”.
8. EXPOSURE CONTROLS AND PERSONAL PROTECTION
Exposure Limits
Component: Aluminum Oxide
ACGIH (TWA): 1 mg/m3 (respirable fraction, related to Aluminum insoluble compounds)
OSHA (TWA): 15 mg/m3 (total dust)
OSHA (TWA):
5 mg/m3 (respirable fraction)
Ventilation: Use local exhaust ventilation system. Ensure compliance with applicable exposure limits. Refer to
the ACGIH document, Industrial Ventilation, a Manual of Recommended Practices.
Respirator: If workplace conditions warrant a respirator, a respiratory protection program that meets
OSHA 29 CFR 1910.134 must be followed. Refer to NIOSH 42 CFR 84 for applicable certified respirators.
Eye Protection: Wear chemical safety goggles. An eye wash station should be readily available near areas of use.
MSDS 699
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Personal Protection:
exposure.
Wear appropriate protective clothing and chemically resistant gloves to prevent skin
9. PHYSICAL AND CHEMICAL PROPERTIES
Property
Aluminum Oxide
White to gray solid, odorless
Appearance and Odor
101.96 g/mol
Molar Mass
Al2O3
Molecular Formula
3.965 g/ml
Density
insoluble
Water Solubility
Melting Point
2053-2072 ºC
Vapor Density (Air=1)
not applicable
1 mm Hg (2158 ºC)
Vapor Pressure
10. STABILITY AND REACTIVITY
Stability:
X
Stable
Unstable
Stable at normal temperatures and pressure.
Conditions to Avoid: Avoid generating dust.
Incompatible Materials: Incompatible with halo carbons, halogens, combustible materials, oxidizing materials.
May initiate explosive polymerization with ethylene oxide.
Fire/Explosion Information: See Section 5, “Fire Fighting Measures”.
Hazardous Decomposition: Thermal decomposition of aluminum oxide can produce miscellaneous decomposition
products.
Will Occur
Hazardous Polymerization:
X
Will Not Occur
11. TOXICOLOGICAL INFORMATION
Route of Entry:
X
Inhalation
X
Skin
Ingestion
Toxicity Data
Rat, Oral LD50: >5000 mg/kg
Health Effects (Acute and Chronic): See Section 2, “Hazards Identification” for potential health effects.
Target Organ(s):
Skin and respiratory tract.
Mutagen/Teratogen:
Aluminum Oxide has been investigated as a possible mutagen and reproductive effector. The following
endpoints are listed in the Registry of Toxic Effects of Chemical Substances (RTECS) for tumorigenic effects.
Rat implant TDLo: 200 mg/kg
12. ECOLOGICAL INFORMATION
Ecotoxicity Data
No ecotoxicity data are available.
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13. DISPOSAL CONSIDERATIONS
Waste Disposal: Dispose in accordance with all applicable federal, state, and local regulations.
14. TRANSPORTATION INFORMATION
U.S. DOT and IATA: This material is not regulated by DOT or IATA.
15. REGULATORY INFORMATION
U.S. REGULATIONS
CERCLA Sections 102a/103 (40 CFR 302.4): Not regulated.
SARA Title III Section 302 (40 CFR 355.30): Not regulated.
SARA Title III Section 304 (40 CFR 355.40): Not regulated.
SARA Title III Section 313 (40 CFR 372.65): 1.0 % de minimis concentrations (fibrous forms)
OSHA Process Safety (29 CFR 1910.119): Not regulated.
SARA Title III Sections 311/312 Hazardous Categories (40 CFR 370.21):
ACUTE HEALTH:
CHRONIC HEALTH:
FIRE:
REACTIVE:
PRESSURE:
No.
Yes.
No.
No.
No.
STATE REGULATIONS
California Proposition 65: Not listed.
CANADIAN REGULATIONS
WHMIS Information: Not provided for this material.
EUROPEAN REGULATIONS
EC Classification
Not classified.
EC Risk Phrases
Not assigned.
EC Safety Phrases
Not assigned.
NATIONAL INVENTORY STATUS
U.S. Inventory (TSCA): Listed in inventory.
TSCA 12(b)
Export Notification: Not listed.
16. OTHER INFORMATION
Sources: ChemAdvisor, Inc., MSDS Aluminum Oxide, 10 June 2011.
Disclaimer: Physical and chemical data contained in this MSDS are provided only for use in assessing the
hazardous nature of the material. The MSDS was prepared carefully, using current references; however, NIST does
not certify the data in the MSDS. The certified values for this material are given in the NIST Certificate of Analysis.
MSDS 699
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