BIOH111 [SESSION 3] Tutorial- CELL COMMUNICATION/CELL DIVISION Learning Outcomes: Describe and understand cell signalling, its components and significance. Describe and understand cell division (mitosis & meiosis), with particular focus on mitosis. Aims: To view and analyse animation on the cellular signaling To view and analyse animation on cell division © Endeavour College of Natural Health Last updated on 18-Jul-16 80bce850e409470d9f17274aef144396 Page 1 of 5 Activity 1: A. Watch the following video animation (2-3 minutes) related to cell signaling, and pay particular attention to the ‘input/processing/output’ cascade of events: https://www.youtube.com/watch?v=FtVb7r8aHco B. Write a summary paragraph outlining the main points of events of cell signaling by answering the following questions: 1. What do you think is the first step of the signaling cascade? ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ 2. Why is this step important? ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ 3. What happens after the initial step and why is this important in the events that happen inside the cells next? ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ © Endeavour College of Natural Health Last updated on 18-Jul-16 80bce850e409470d9f17274aef144396 Page 2 of 5 4. Describe the intracellular events that happen once the G-protein is activated (you can use the lecture slides as a guide also). ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ 5. What is the outcome of the signaling cascade? Why does it need to happen? ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ Activity 2: A. Watch the following cell divisions animation: https://www.spongelab.com/browse/index.cfm (search “thread of life”, then watch the video about mitosis) 1 minute https://www.khanacademy.org/science/biology/cellular-molecularbiology/mitosis/v/mitosis (mitosis) 12 minutes https://www.spongelab.com/browse/index.cfm (search “crash course biolo”, then watch the video about meiosis) 6 minutes B. Outline all the stages that somatic cells go through when they divide (i.e. mitosis). ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ © Endeavour College of Natural Health Last updated on 18-Jul-16 80bce850e409470d9f17274aef144396 Page 3 of 5 ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ C. Answer the following questions: 1. In which mitotic stage (phase) does DNA replication occur and how? ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ 2. What happens during late prophase of mitosis? ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ 3. What happens during Anaphase? ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ © Endeavour College of Natural Health Last updated on 18-Jul-16 80bce850e409470d9f17274aef144396 Page 4 of 5 ________________________________________________________________ ________________________________________________________________ 4. If (2n) is the total number of chromosomes of the mother cell just before entering mitosis, what will be the total number of chromosomes for the 2 daughter cells? ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ 5. Which cell division mechanism is similar to mitosis: meiosis I? or meiosis II ? ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ ________________________________________________________________ Go back to your cell concept map and incorporate into it cellular signalling and where cell division starts. Composed by Dr Akram Kabbara © Endeavour College of Natural Health Last updated on 18-Jul-16 80bce850e409470d9f17274aef144396 Page 5 of 5
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