ECG of the Month Hide and Seek Keith J. C. Finnie, MB, ChB, FRCPC An 80-year-old woman complains of recurrent self-limiting episodes of palpitations. An ECG (Figure 1) is obtained during a typical episode. Figure 1. ECG obtained during a typical episode of palpitations. 1. What is the differential diagnosis for the arrhythmia shown? © t n h o i t g i u r b i y str i D Cop l a i rc ad, ownlo d n e a c ers mm o ised us personal use C r o r h t u o A or correct diagnosis? 2. What measures might d. establishing fthe le sbee phelpful ein a S e copy rohibit l r g n i o s f u Not uthorised and print a Una , view display Perspectives in Cardiology / April 2008 1 ECG of the Month This Month’s ECG Diagnosis ECG shows a regular narrow QRS com1. The plex tachycardia at 115 bpm. In lead V , each 1 QRS complex can be seen to be preceded by P waves. Examination of lead II reveals that the P wave morphology is not consistent with origin from the sinus node; the P waves are of very low amplitude and have a slightly negative polarity. This is not sinus tachycardia with a long PR interval, but some other form of regular supraventricular tachycardia (SVT). When dealing with SVT where the P waves are visible, the relationship of the P waves to the preceding and following QRS complexes can be helpful. Short RP intervals (P wave closer to the preceding QRS than the following one) are seen in the common form (slow antegrade pathway, fast retrograde pathway) of atrioventricular node reentrant tachycardia (AVNRT) and in atrioventricular reentrant tachycardia (AVRT) utilizing retrograde conduction over an accessory pathway. In AVNRT the retrograde P wave is usually closer to the QRS complex than in AVRT and may be obscured within the terminal portion of the QRS complex. Long RP intervals (P wave closer to the following QRS than to the preceding one) are suggestive of: • an ectopic atrial tachycardia, • the uncommon form of AVNRT (antegrade conduction via a fast pathway and retrograde conduction via a slow pathway) and • AVRT with slow retrograde conduction through an accessory pathway. In this patient, the P waves are approximately mid-way between the QRS complexes, making characterization by RP interval difficult. hen dealing with SVT where the P waves are visible, the relationship of the P waves to the preceding and following QRS complexes can be helpful. W Angiotensin II Receptor Blocker Angiotensin II Receptor Blocker/Diuretic Please consult product monographs for warnings and precautions. Product monographs available upon request at 1-866-INFO BMS (1-866-463-6267), Bristol-Myers Squibb Canada, 2365 Côte-de-Liesse, Saint-Laurent, Quebec H4N 2M7. An agreement between Bristol-Myers Squibb and sanofi-aventis for the codevelopment and marketing of irbesartan and clopidogrel, two compounds from sanofi-aventis research. CDN.IRB.06.02.11E ECG of the Month 2. The diagnosis and treatment of regular SVT can often be assisted by the response of the arrhythmia to measures which slow AV node conduction. Carotid sinus massage and Valsalva strain can be performed at the bedside and a response is likely to be diagnostic; the absence of a response is not helpful. Alternatively, IV adenosine will profoundly and transiently slow AV node conduction and may be given safely with ECG and BP monitoring. This patient received 6 mg of IV adenosine and the response is shown in Figure 2. AV node conduction is blocked for a few seconds, revealing twice as many P waves as had been suspected initially. The rhythm is atrial tachycardia with 2:1 AV conduction, possibly due to enhanced atrial automaticity or intra-atrial reentry. Because it does not require the AV node to sustain it, AV node blockade will not terminate atrial tachycardia. And, because the initial ECG only revealed every other P wave, attempts to characterize this patient’s arrhythmia by RP relationship are rendered invalid and likely to prove misleading. PCard PCard Figure 2. ECG showing patient’s response after IV adenosine. Dr. Finnie is a Professor, Department of Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario and a Cardiologist, LHSC University Hospital, London, Ontario. Publication Mail Agreement No.: 40063348 Return undeliverable Canadian addresses to: STA Communications Inc. 955 St. Jean Blvd., Suite 306 Pointe-Claire, QC, H9R 5K3 Perspectives in Cardiology / April 2008 3
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