Contents
Acetic acid 96% or above
Acetone
Acetonitrile
Acetylcholine Chloride, 99% (titr.) [Fisher Rev# 2]
Ammonium Hydroxide 29.7 %
Ammonium sulfate
Benzalkonium Chloride
Calcium Phosphate Tribasic
Carbowax PEG 400
Chloroform
Collodion, Flexible
ColoScreen Developer 15
ColoScreen Developer 2
DeRoyal solidifier
Dichloromethane
Dimethyl Sulfoxide
Epsom Salt
Ethanol(95%), 190 Proof
Ethanol, 200 Proof
Ethyl Alcohol, Denatured, 70% Solution
Ethyl Chloride
Ethyl ether
Ethylenediamine Tetraacetic Acid, Disodium Salt, Dihydrate
FERRIC SUBSULFATE SOLUTION
Formaldehyde Solution 37%
Gastroccult Developer
Gentian Violet
Glycerin
Hexane
Histoprep 80% alcohol
Hydrochloric acid 33-38% solution
Iodine Solutions 1N and Lugol
Isopropanol, p.a.
Isopropyl Alcohol 70%
L-Glutamine
Methanol
Mineral Oil, Light and Heavy
Phenol Liquid
Phenol, Crystallized
Podocon-25
Potassium Hydroxide Solution, 10.0%
Propylene glycol
Reagent Alcohol 70%
RESORCINOL
Silver nitrate
Sodium Benzoate
Sodium Bicarbonate
Sodium Chloride
Sodium hydroxide, solid
Sodium sulfate anhydrous
Soft 'N Sure Skin Cleanser
Sulfuric acid 90-98%
Tetracaine
Toluene
Trichloroacetic Acid Solution
Urea
Xylenes, mixed isomers with ethylbenzene
Material Safety Data Sheet
Acetic acid, >96%
ACC# 00120
Section 1 - Chemical Product and Company Identification
MSDS Name: Acetic acid, >96%
Catalog Numbers: AC124040000, AC124040010, AC124040025, AC124040250,
AC148930000, AC148930010, AC148930025, AC222140000, AC222140010,
AC222140025, AC222140200, AC222142500, AC295320000, AC295320010,
AC295320025, AC423220000, AC423220025, AC423225000, AC0360, AC0400, S70048,
S70048-1SC, S70048SC, A35-500, A35-500LC, A38-212, A38-450LB, A38-500, A38500LC, A38212LC, A38500LC, A38C-212, A38C212LC, A38J500, A38P-20, A38P500,
A38S-212, A38S-500, A38SI-212, A465-1, A465-250, A465-500, A490-212, A491-20,
A491-212, A491-212LC, A491-4, A507-212, A507-4, A507-500, A507SK-212, BP1185500, BP2400-500, BP2401-212, BP2401-500, BP2401C-212, BP2401P-20, BP2401S-212,
BP2401S-500, BP2401SI-212, FLA38500LC, NC9011470, NC9532182, S70048-2MF
Synonyms: Ethanoic acid; Ethylic acid; Methanecarboxylic acid; Vinegar acid.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
64-19-7
Chemical Name
Acetic acid
Percent
EINECS/ELINCS
>96
200-580-7
Hazard Symbols: C
Risk Phrases: 10 35
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: clear, colorless liquid. Flash Point: 39 deg C. Danger! Causes severe eye
and skin burns. Causes severe digestive and respiratory tract burns. Flammable liquid
and vapor. Corrosive to metal. May be harmful if absorbed through the skin. Acetic acid
forms ice-like solid below 62°F (17°C).
Target Organs: Teeth, eyes, skin, mucous membranes.
Potential Health Effects
Eye: Causes severe eye irritation. Contact with liquid or vapor causes severe burns and
possible irreversible eye damage.
Skin: Causes skin burns. May be harmful if absorbed through the skin. Contact with the
skin may cause blackening and hyperkeratosis of the skin of the hands.
Ingestion: May cause severe and permanent damage to the digestive tract. Causes
severe pain, nausea, vomiting, diarrhea, and shock. May cause polyuria, oliguria
(excretion of a diminished amount of urine in relation to the fluid intake) and anuria
(complete suppression of urination). Rapidly absorbed from the gastrointestinal tract.
Inhalation: Effects may be delayed. Causes chemical burns to the respiratory tract.
Exposure may lead to bronchitis, pharyngitis, and dental erosion. May be absorbed
through the lungs.
Chronic: Chronic exposure to acetic acid may cause erosion of dental enamel, bronchitis,
eye irritation, darkening of the skin, and chronic inflammation of the respiratory tract.
Acetic acid can cause occupational asthma. One case of a delayed asthmatic response to
glacial acetic acid has been reported in a person with bronchial asthma. Skin sensitization
to acetic acid is rare, but has occurred.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid immediately.
Skin: In case of contact, immediately flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Get medical aid immediately.
Wash clothing before reuse.
Ingestion: If swallowed, do NOT induce vomiting. Get medical aid immediately. If victim
is fully conscious, give a cupful of water. Never give anything by mouth to an
unconscious person.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Persons with pre-existing skin disorders or impaired respiratory or
pulmonary function may be at increased risk to the effects of this substance. Treat
symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Use water spray to keep fire-exposed containers cool.
Reacts with most metals to form highly flammable hydrogen gas which can form
explosive mixtures with air. Flammable liquid and vapor. Vapors are heavier than air and
may travel to a source of ignition and flash back. Vapors can spread along the ground
and collect in low or confined areas.
Extinguishing Media: Use water spray, dry chemical, "alcohol resistant" foam, or
carbon dioxide.
Flash Point: 39 deg C ( 102.20 deg F)
Autoignition Temperature: 426 deg C ( 798.80 deg F)
Explosion Limits, Lower:4.0 vol %
Upper: 19.9 vol %
NFPA Rating: (estimated) Health: 3; Flammability: 2; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Wash area with soap and water. Remove all sources of
ignition. Use a spark-proof tool. Provide ventilation. Use water spray to cool and disperse
vapors, protect personnel, and dilute spills to form nonflammable mixtures. Control
runoff and isolate discharged material for proper disposal. Spill may be carefully
neutralized with soda ash (sodium carbonate).
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Ground and bond containers when transferring material. Do not get in eyes,
on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor),
and can be dangerous. Discard contaminated shoes. Do not pressurize, cut, weld, braze,
solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only
with adequate ventilation. Keep away from heat, sparks and flame. Do not breathe vapor
or mist. Use corrosion-resistant transfer equipment when dispensing.
Storage: Keep away from heat, sparks, and flame. Keep from contact with oxidizing
materials. Store in a cool, dry, well-ventilated area away from incompatible substances.
Do not store near alkaline substances. Acetic acid should be kept above its freezing point
of 62°F(17°C) to allow it to be handled as a liquid. It will contract slightly on freezing.
Freezing and thawing does not affect product quality.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible exposure limits. Use a
corrosion-resistant ventilation system.
Exposure Limits
Chemical Name
Acetic acid
ACGIH
10 ppm TWA; 15 ppm
STEL
NIOSH
OSHA - Final PELs
10 ppm TWA; 25 mg/
m3 TWA 50 ppm IDLH
10 ppm TWA; 25 mg/
m3 TWA
OSHA Vacated PELs: Acetic acid: 10 ppm TWA; 25 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear chemical goggles and face shield.
Skin: Wear appropriate gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear, colorless
Odor: pungent odor - vinegar odor
pH: <.01
Vapor Pressure: 11.4 mm Hg @ 20 deg C
Vapor Density: 2.10 (Air=1)
Evaporation Rate:0.97 (n-Butyl acetate=1)
Viscosity: 1.22 cP
Boiling Point: 117-118 deg C
Freezing/Melting Point:16.6 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:1.05 (Water=1)
Molecular Formula:C2H4O2
Molecular Weight:60.04
Section 10 - Stability and Reactivity
Chemical Stability: Stable at room temperature in closed containers under normal
storage and handling conditions.
Conditions to Avoid: Ignition sources, excess heat, freezing temperatures, confined
spaces, Note: Use great caution in mixing with water due to heat evolution that causes
explosive spattering. Always add the acid to water, never the reverse..
Incompatibilities with Other Materials: Metals, strong oxidizing agents, bases,
chlorine trifluoride, nitric acid, acetaldehyde, chlorosulfonic acid, oleum, bromine
pentafluoride, perchloric acid, potassium tert-butoxide, ethyleneimine, 2-aminoethanol,
ethylene diamine, phosphorus trichloride, phosphorus isocyanate, chromic acid.
Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 64-19-7: AF1225000
LD50/LC50:
CAS# 64-19-7:
Draize test, rabbit, skin: 50 mg/24H Mild;
Inhalation, mouse: LC50 = 5620 ppm/1H;
Oral, rat: LD50 = 3310 mg/kg;
Skin, rabbit: LD50 = 1060 uL/kg;
Carcinogenicity:
CAS# 64-19-7: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No teratogenic effects were observed among the offspring of mice, rats,
or rabbits that had been given very large doses of apple cider vinegar (containing acetic
acid) during pregnancy.
Reproductive Effects: Intratesticular, rat: TDLo = 400 mg/kg (male 1 day(s) premating) Fertility - male fertility index (e.g. # males impregnating females per # males
exposed to fertile nonpregnant females).
Neurotoxicity: No information available.
Mutagenicity: Sister Chromatid Exchange: Human, Lymphocyte = 5 mmol/L.;
Unscheduled DNA Synthesis: Administration onto the skin, mouse = 79279 ug/kg.;
Cytogenetic Analysis: Hamster, Ovary = 10 mmol/L.
Other Studies: See actual entry in RTECS for complete information.
Section 12 - Ecological Information
Ecotoxicity: Fish: Fathead Minnow: LC50 = 88 mg/L; 96 Hr; Static bioassay @ 18-22°
CFish: Bluegill/Sunfish: LC50 = 75 mg/L; 96 Hr; UnspecifiedFish: Goldfish: LC50 = 423
mg/L; 24 Hr; UnspecifiedWater flea Daphnia: EC50 = 32-47 mg/L; 24-48 Hr;
UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 = 8.86-11 mg/L; 5,15,25 min;
Microtox test If released to water or soil, acetic acid will biodegrade readily. Evaporation
from dry surfaces is likely to occur. When spilled on soil, the liquid will spread on the
surface and penetrate into the soil at a rate dependent on the soil type and its water
content. Acetic acid shows no potential for biological accumulation or food chain
contamination.
Environmental: If released to the atmosphere, it is degraded in the vapor-phase by
reaction with photochemically produced hydroyxl radicals (estimated typical half-life of
26.7 days). It occurs in atmospheric particulate matter in acetate form and physical
removal from air can occur via wet and dry deposition.
Physical: Natural waters will neutralize dilute solutions to acetate salts.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
ACETIC
ACID,
GLACIAL
Hazard Class: 8
UN Number:
Canada TDG
ACETIC ACID
GLACIAL
8(3)
UN2789
Packing Group: II
UN2789
II
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 64-19-7 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 64-19-7: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 64-19-7: acute, chronic, flammable.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
CAS# 64-19-7 is listed as a Hazardous Substance under the CWA. None of the chemicals
in this product are listed as Priority Pollutants under the CWA. None of the chemicals in
this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 64-19-7 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
C
Risk Phrases:
R 10 Flammable.
R 35 Causes severe burns.
Safety Phrases:
S 23 Do not inhale gas/fumes/vapour/spray.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 64-19-7: 1
Canada - DSL/NDSL
CAS# 64-19-7 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B3, E.
Canadian Ingredient Disclosure List
CAS# 64-19-7 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 64-19-7: OEL-AUSTRALIA:TWA 10 ppm (25 mg/m3);STEL 15 ppm (37 mg
/m3) OEL-AUSTRIA:TWA 10 ppm (25 mg/m3) OEL-BELGIUM:TWA 10 ppm (25 mg
/m3);STEL 15 ppm (37 mg/m3) OEL-CZECHOSLOVAKIA:TWA 25 mg/m3;STEL 50 m
g/m3 OEL-DENMARK:TWA 10 ppm (25 mg/m3) OEL-FINLAND:TWA 10 ppm (25 mg
/m3);STEL 15 ppm (37 mg/m3);Skin OEL-FRANCE:STEL 10 ppm (25 mg/m3) O
EL-GERMANY:TWA 10 ppm (25 mg/m3) OEL-HUNGARY:TWA 10 mg/m3;STEL 20 mg/
m3 OEL-INDIA:TWA 10 ppm (25 mg/m3);STEL 15 ppm (37 mg/m3) OEL-JAPAN:
TWA 10 ppm (25 mg/m3) OEL-THE NETHERLANDS:TWA 10 ppm (25 mg/m3) OELTHE PHILIPPINES:TWA 10 ppm (25 mg/m3) OEL-POLAND:TWA 5 mg/m3 OEL-RUS
SIA:TWA 10 ppm;STEL 5 mg/m3;Skin OEL-SWEDEN:TWA 10 ppm (25 mg/m3);STE
L 15 ppm (35 mg/m3) OEL-SWITZERLAND:TWA 10 ppm (25 mg/m3);STEL 20 ppm
(50 mg/m3) OEL-THAILAND:TWA 10 ppm (25 mg/m3) OEL-TURKEY:TWA 10 ppm
(25 mg/m3) OEL-UNITED KINGDOM:TWA 10 ppm (25 mg/m3);STEL 15 ppm (35
mg/m3) OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL
IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 7/21/1999
Revision #9 Date: 6/17/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Acetone
ACC# 00140
Section 1 - Chemical Product and Company Identification
MSDS Name: Acetone
Catalog Numbers: AC167640000, AC167640025, AC167645000, AC176800000,
AC176800010, AC176800025, AC176805000, AC177170000, AC177170010,
AC177170025, AC177170250, AC177179090, AC268310000, AC268310010,
AC268310025, AC268310040, AC326570000, AC326570010, AC326570025,
AC326700000, AC326700010, AC326700025, AC326740000, AC326740010,
AC326740025, AC326800000, AC326800010, AC326801000, AC326802500,
AC327840000, AC327840010, AC327840040, AC400100000, AC400100010,
AC400100025, AC400100040, AC400105000, AC423240000, AC423240010,
AC423240040, AC423245000, AC611010040, A19RS115, S70090, S70091, S70091-1,
A11-1, A11-20, A11-200, A11-4, A11S-4, A16F-1GAL, A16P-4, A16P1GAL, A16S-20,
A16S-4, A18-1, A18-20, A18-200, A18-4, A18-500, A18CU-1300, A18FB115, A18FB19,
A18FB200, A18FB50, A18J500, A18P-4, A18POP19, A18POP200, A18POP50, A18POPB19,
A18POPB200, A18POPB50, A18RB-115, A18RB-19, A18RB-200, A18RB-50, A18RS-115,
A18RS-200, A18RS-28, A18RS-50, A18S-4, A18SK-4, A18SS-115, A18SS-200, A18SS28, A18SS-50, A18SS1350, A18SS19, A19-1, A19-4, A40-4, A404LC, A920, A9200, A9284, A929-1, A929-4, A929J1, A929J4, A929POP19, A929POP200, A929POP50, A929RS-19,
A929RS-200, A929RS-50, A929SS-115, A929SS-200, A929SS-28, A929SS-50,
A929SS19, A94, A946-4, A9464LC, A946FB19, A946FB200, A946FB50, A946POPB19,
A946POPB200, A946POPB50, A946RB115, A946RB19, A946RB200, A946RB50, A949-1,
A949-4, A9491LC, A949CU50, A949J1, A949J4, A949N119, A949N219, A949NB219,
A949POP19, A949POP200, A949POP50, A949POPN19, A949RS-115, A949RS-28, A949RS50, A949SK-1, A949SK-4, A949SK4LC, A949SS-115, A949SS-200, A949SS-28, A949SS50, A949SS19, BP24011, BP240320, BP24034, BP2403500, BP24044, BP2404SK1,
BP2404SK4, HC3001GAL, JONA18, NC9060899, NC9096457, NC9120377, NC9173151,
NC9475452, NC9614315, NC9905244, PS03488, PS03489
Synonyms: Dimethylketone; 2-Propanone.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
67-64-1
Chemical Name
Acetone
Percent
EINECS/ELINCS
>99
200-662-2
Hazard Symbols: XI F
Risk Phrases: 11 36
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: clear, colorless liquid. Flash Point: -20 deg C. Causes eye irritation.
Breathing vapors may cause drowsiness and dizziness. Prolonged or repeated contact
may dry the skin and cause irritation. Danger! Extremely flammable liquid and vapor.
Vapor may cause flash fire. Aspiration hazard if swallowed. Can enter lungs and cause
damage. Causes respiratory tract irritation.
Target Organs: Central nervous system, respiratory system, eyes, skin.
Potential Health Effects
Eye: Produces irritation, characterized by a burning sensation, redness, tearing,
inflammation, and possible corneal injury. Vapors cause eye irritation.
Skin: May be absorbed through the skin. Repeated or prolonged exposure may cause
drying and cracking of the skin.
Ingestion: May cause irritation of the digestive tract. May cause central nervous system
depression, characterized by excitement, followed by headache, dizziness, drowsiness,
and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible
death due to respiratory failure. Aspiration of material into the lungs may cause chemical
pneumonitis, which may be fatal.
Inhalation: Inhalation of high concentrations may cause central nervous system effects
characterized by nausea, headache, dizziness, unconsciousness and coma. Causes
respiratory tract irritation. May cause motor incoordination and speech abnormalities.
Chronic: Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation
may cause effects similar to those of acute inhalation. Matsushita et al. exposed human
volunteers 6 hours/day for 6 days at 5 00 ppm and found hematologic changes including
significantly increased leukocyte and eosinophil counts and decreased neutrophil
phagocytic a ctivity.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid.
Skin: In case of contact, flush skin with plenty of water. Remove contaminated clothing
and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion: Potential for aspiration if swallowed. Get medical aid immediately. Do not
induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: Containers can build up pressure if exposed to heat and/or fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/
NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and
highly toxic gases may be generated by thermal decomposition or combustion. Use water
spray to keep fire-exposed containers cool. Extremely flammable liquid and vapor. Vapor
may cause flash fire. Vapors are heavier than air and may travel to a source of ignition
and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media: Use dry chemical, carbon dioxide, or appropriate foam. Water
may be ineffective because it will not cool material below its flash point.
Flash Point: -20 deg C ( -4.00 deg F)
Autoignition Temperature: 465 deg C ( 869.00 deg F)
Explosion Limits, Lower:2.5%
Upper: 12.8%
NFPA Rating: (estimated) Health: 1; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Avoid runoff into storm sewers and ditches which lead to
waterways. Wear appropriate protective clothing to minimize contact with skin. Remove
all sources of ignition. Provide ventilation. A vapor suppressing foam may be used to
reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed
spaces. Use only non-sparking tools and equipment.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Ground and bond containers when transferring material. Avoid contact with
eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor),
and can be dangerous. Keep container tightly closed. Do not pressurize, cut, weld, braze,
solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only
with adequate ventilation. Keep away from heat, sparks and flame. Avoid breathing
vapor.
Storage: Keep away from sources of ignition. Store in a tightly closed container. Store in
a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible exposure limits.
Ventilation fans and other electrical service must be non-sparking and have an explosionproof design.
Exposure Limits
Chemical Name
Acetone
ACGIH
500 ppm TWA; 750
ppm STEL
NIOSH
OSHA - Final PELs
250 ppm TWA; 590 mg/
m3 TWA 2500 ppm IDLH
1000 ppm TWA; 2400
mg/m3 TWA
OSHA Vacated PELs: Acetone: 750 ppm TWA; 1800 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or
European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved
respirator when necessary.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear, colorless
Odor: sweetish odor
pH: 7
Vapor Pressure: 231 mm Hg @ 25 deg C
Vapor Density: 2.0 (Air=1)
Evaporation Rate:5.6 (n-Butyl acetate=1)
Viscosity: 0.32 cps @ 20 deg C
Boiling Point: 56 deg C
Freezing/Melting Point:-94 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:0.788 @ 25°C
Molecular Formula:C3H6O
Molecular Weight:58.08
Section 10 - Stability and Reactivity
Chemical Stability: Stable at room temperature in closed containers under normal
storage and handling conditions.
Conditions to Avoid: High temperatures, ignition sources, confined spaces.
Incompatibilities with Other Materials: Strong oxidizing agents, strong reducing
agents, strong bases, nitric acid, hexachloromelamine, sulfur dichloride, potassium tertbutoxide, chloroform + alkali, sulfuric acid + nitric acid.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 67-64-1: AL3150000
LD50/LC50:
CAS# 67-64-1:
Dermal, guinea pig: LD50 = >9400 uL/kg;
Draize test, rabbit, eye: 20 mg Severe;
Draize test, rabbit, eye: 20 mg/24H Moderate;
Draize test, rabbit, eye: 10 uL Mild;
Draize test, rabbit, skin: 500 mg/24H Mild;
Inhalation, mouse: LC50 = 44 gm/m3/4H;
Inhalation, rat: LC50 = 50100 mg/m3/8H;
Oral, mouse: LD50 = 3 gm/kg;
Oral, rabbit: LD50 = 5340 mg/kg;
Oral, rat: LD50 = 5800 mg/kg;
Carcinogenicity:
CAS# 67-64-1: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: During the Stewart et al. study, four adult female volunteers
were exposed 7.5 hours to acetone vapor at a nominal concentration of 1000 ppm. Three
of the four women experienced premature menstrual periods which were attributed to the
acetone exposure.
Neurotoxicity: No information available.
Mutagenicity: Sex chromosome loss and nondisjunction(Yeast - Saccharomyces
cerevisiae) = 47600 ppm; Cytogenetic analysis(Rodent - hamster Fibroblast)= 40 gm/L.
Other Studies: Standard Draize Test: Administration onto the skin (human) = 500
mg/7days (Mild). Standard Draize Test: Administrat ion onto the skin (rabbit) = 500
mg/24H (Mild). Standard D raize Test( Eye, Rabbit) = 20 mg; Severe.
Section 12 - Ecological Information
Ecotoxicity: Fish: Rainbow trout: 5540 mg/l; 96-hr; LC50Fish: Bluegill/Sunfish: 8300
mg/l; 96-hr; LC50 No data available.
Environmental: Volatilizes, leeches, and biodegrades when released to soil.
TERRESTRIAL FATE: If released on soil, acetone will both volatilize and leach into the
ground. Acetone readily biodegrades and there is evidence suggesting that it biodegrades
fairly rapidly in soils. AQUATIC FATE: If released into water, acetone will probably
biodegrade. It is readily biodegradable in screening tests, although data from natural
water are lacking. It will also be lost due to volatilization (estimated half-life 20 hr from a
model river). Adsorption to sediment should not be significant.
Physical: ATMOSPHERIC FATE: In the atmosphere, acetone will be lost by photolysis and
reaction with photochemically produced hydroxyl radicals. Half-life estimates from these
combined processes are 79 and 13 days in January and June, respectively, for an overall
annual average of 22 days. Therefore considerable dispersion should occur. Being
miscible in water, wash out by rain should be an important removal process. This process
has been confirmed around Lake Shinsei-ko in Japan. There acetone was found in the air
and rain as well as the lake.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 67-64-1: waste number U002 (Ignitable waste).
Section 14 - Transport Information
US DOT
Shipping
Name:
ACETONE
Hazard Class: 3
IATA
RID/ADR
IMO
Canada TDG
ACETONE
3
UN Number:
UN1090
Packing Group: II
UN1090
II
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 67-64-1 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 67-64-1: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 67-64-1: acute, flammable.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 67-64-1 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XI F
Risk Phrases:
R 11 Highly flammable.
R 36 Irritating to eyes.
R 66 Repeated exposure may cause skin dryness or
cracking.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 9 Keep container in a well-ventilated place.
WGK (Water Danger/Protection)
CAS# 67-64-1: 0
Canada - DSL/NDSL
CAS# 67-64-1 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2B.
Canadian Ingredient Disclosure List
CAS# 67-64-1 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 67-64-1: OEL-AUSTRALIA:TWA 500 ppm (1185 mg/m3);STEL 1000 ppm
OEL-AUSTRIA:TWA 750 ppm (1780 mg/m3) OEL-BELGIUM:TWA 750 ppm (1780 mg
/m3);STEL 1000 pp OEL-CZECHOSLOVAKIA:TWA 800 mg/m3;STEL 4000 mg/m3 O
EL-DENMARK:TWA 250 ppm (600 mg/m3) OEL-FINLAND:TWA 500 ppm (1200 mg/m
3);STEL 625 ppm (1500 mg/m3) OEL-FRANCE:TWA 750 ppm (1800 mg/m3) OEL
-GERMANY:TWA 1000 ppm (2400 mg/m3) OEL-HUNGARY:TWA 600 mg/m3;STEL 120
0 mg/m3 OEL-INDIA:TWA 750 ppm (1780 mg/m3);STEL 1000 ppm (2375 mg/m3)
OEL-JAPAN:TWA 200 ppm (470 mg/m3) OEL-THE NETHERLANDS:TWA 750 ppm (
1780 mg/m3) JAN9 OEL-THE PHILIPPINES:TWA 1000 ppm (2400 mg/m3) OEL-P
OLAND:TWA 200 mg/m3 OEL-RUSSIA:TWA 200 ppm;STEL 200 mg/m3 OEL-SWEDEN
:TWA 250 ppm (600 mg/m3);STEL 500 ppm (1200 mg/m3) OEL-SWITZERLAND:TW
A 750 ppm (1780 mg/m3) OEL-TURKEY:TWA 1000 ppm (2400 mg/m3) OEL-UNIT
ED KINGDOM:TWA 750 ppm (1810 mg/m3);STEL 1250 ppm OEL IN BULGARIA, CO
LOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE,
VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 7/26/1999
Revision #15 Date: 3/05/2004
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Acetonitrile
ACC# 00170
Section 1 - Chemical Product and Company Identification
MSDS Name: Acetonitrile
Catalog Numbers: AC149520010, AC149520025, AC149520250, AC149525000,
AC167650010, AC167652500, AC258560010, AC258560025, AC268260010,
AC268260025, AC268270010, AC268270025, AC268270040, AC325730010,
AC325730025, AC326680010, AC326680025, AC326750010, AC326750025,
AC326810010, AC326811000, AC326812500, AC364310010, AC364311000,
AC400132500, AC423250010, AC423255000, AC610010040, AC610130040,
AC610220010, AC610221000, AC610500190, AC610500500, AC610501150,
AC610502000, AC610700190, AC610700500, AC610701150, AC610702000,
AC610961000, AC611100500, S70092HPLC, A21-1, A21-20, A21-200, A21-4, A21200LC,
A21FB115, A21FB19, A21FB200, A21FB50, A21RB115, A21RS115, A21RS200, A21RS28,
A9931, A993RS19, A996-1, A996-4, A9964LC, A996N219, A996POP200, A996RS-115,
A996RS-200, A996RS-28, A996RS-50, A996SS115, A996SS19, A996SS200, A996SS28,
A996SS50, A998-1, A998-4, A998212, A9984LC, A998J1, A998N119, A998N219,
A998POP50, A998RS115, A998RS19, A998RS200, A998RS28, A998RS50, A998SK-1,
A998SK-4, A998SS-115, A998SS-200, A998SS-28, A998SS-50, A998SS1350, A999-4,
BP1165-50, BP1170-4, BP11704004, BP1170450, BP1170N119, BP1170N219,
BP1170POP20, BP1170POP50, BP1170POPN1, BP1170RS-1350, BP1170RS115,
BP1170RS19, BP1170RS200, BP1170RS28, BP1170RS50, BP1170SS-115, BP1170SS200, BP1170SS-30, BP1170SS-50, BP24051, BP24054, BP2405SK1, BP2405SK4, BP2600100, NC9173153, NC9308642, NC9474163, NC9533032, NC9708859, NC9833088,
O1034-500, PS03490, PS03491, XXA99820LI, XXA998U20LIN
Synonyms: Cyanomethane; Ethanenitrile; Ethyl nitrile; Methyl cyanide.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
75-05-8
Chemical Name
Acetonitrile
Percent
EINECS/ELINCS
100
200-835-2
Hazard Symbols: XN F
Risk Phrases: 11 20/21/22 36
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: clear, colorless liquid. Flash Point: 6 deg C. Warning! May cause central
nervous system depression. May cause liver and kidney damage. May cause reproductive
and fetal effects. Lachrymator (substance which increases the flow of tears). Hygroscopic
(absorbs moisture from the air). Metabolized to cyanide in the body, which may cause
headache, dizziness, weakness, unconsciousness, convulsions, coma and possible death.
Flammable liquid and vapor. Harmful if swallowed or absorbed through the skin.
Causes eye irritation. May cause skin and respiratory tract irritation. May be harmful if
inhaled.
Target Organs: Blood, kidneys, central nervous system, liver, lungs.
Potential Health Effects
Eye: Causes eye irritation. Lachrymator (substance which increases the flow of tears).
May produce superficial reversible injury.
Skin: Causes mild skin irritation. Harmful if absorbed through the skin. May be
metabolized to cyanide which in turn acts by inhibiting cytochrome oxidase impairing
cellular respiration.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May
cause effects similar to those for inhalation exposure. May cause tissue anoxia,
characterized by weakness, headache, dizziness, confusion, cyanosis (bluish skin due to
deficient oxygenation of the blood), weak and irregular heart beat, collapse,
unconsciousness, convulsions, coma and death. May cause central nervous system
depression. Metabolism may release cyanide, which may result in headache, dizziness,
weakness, collapse, unconsciousness and possible death.
Inhalation: Aspiration may lead to pulmonary edema. Vapors may cause dizziness or
suffocation. Causes upper respiratory tract irritation. May be metabolized to cyanide
which in turns act by inhibiting cytochrome oxidase impairing cellular respiration. May
cause tissue anoxia, characterized by weakness, headache, dizziness, confusion, cyanosis
(bluish discoloration of skin due to deficient oxygenation of the blood), weak and
irregular heart beat, collapse, unconsciousness, convulsions, coma and death.
Chronic: Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation
and ingestion may cause effects similar to those of acute inhalation and ingestion. May
cause liver and kidney damage. May be metabolized to cyanide which in turn acts by
inhibiting cytochrome oxidase impairing cellular respiration. Animal studies have reported
that fetal effects/abnormalities may occur when maternal toxicity is seen. Laboratory
experiments have resulted in mutagenic effects. Exposure to small amounts of cyanide
compounds over long periods of time is reported to cause loss of appetite, headache,
weakness, nausea, dizziness, and symptoms of irritation of the upper respiratory tract
and eyes.
Section 4 - First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to
rub eyes or keep eyes closed.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes. Wash clothing before
reuse.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. Get medical aid
immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air
immediately. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician: Exposure should be treated as a cyanide poisoning. Effects may be
delayed. For methemoglobinemia, administer oxygen alone or with Methylene Blue
depending on the methemoglobin concentration in the blood. May be partially
metabolized to cyanide in the body.
Antidote: Always have a cyanide antidote kit on hand when working with cyanide
compounds. Get medical advice to use. Methylene blue, alone or in combination with
oxygen is indicated as a treatment in nitrite induced methemoglobinemia.
Section 5 - Fire Fighting Measures
General Information: Containers can build up pressure if exposed to heat and/or fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/
NIOSH (approved or equivalent), and full protective gear. Water runoff can cause
environmental damage. Dike and collect water used to fight fire. Vapors may form an
explosive mixture with air. During a fire, irritating and highly toxic gases may be
generated by thermal decomposition or combustion. Use water spray to keep fireexposed containers cool. Water may be ineffective. Material is lighter than water and a
fire may be spread by the use of water. Flammable liquid and vapor. Approach fire from
upwind to avoid hazardous vapors and toxic decomposition products. Vapors are heavier
than air and may travel to a source of ignition and flash back. Vapors can spread along
the ground and collect in low or confined areas.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be
ineffective. Do NOT use straight streams of water. For large fires, use dry chemical,
carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding
quantities of water until well after fire is out.
Flash Point: 6 deg C ( 42.80 deg F)
Autoignition Temperature: 524 deg C ( 975.20 deg F)
Explosion Limits, Lower:3.0 vol %
Upper: 16.00 vol %
NFPA Rating: (estimated) Health: 2; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material
such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust.
Provide ventilation. A vapor suppressing foam may be used to reduce vapors. Water
spray may reduce vapor but may not prevent ignition in closed spaces. Approach spill
from upwind.
Section 7 - Handling and Storage
Handling: Remove contaminated clothing and wash before reuse. Use only in a wellventilated area. Ground and bond containers when transferring material. Do not breathe
dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers
retain product residue, (liquid and/or vapor), and can be dangerous. Keep container
tightly closed. Keep away from heat, sparks and flame. Do not ingest or inhale. Do not
pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat,
sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition.
Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a
cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
Store protected from moisture.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility and a safety shower.
Use adequate general or local exhaust ventilation to keep airborne concentrations below
the permissible exposure limits.
Exposure Limits
Chemical Name
Acetonitrile
ACGIH
20 ppm TWA; skin potential for cutaneous
absorption
NIOSH
OSHA - Final PELs
20 ppm TWA; 34 mg/
m3 TWA 500 ppm IDLH
40 ppm TWA; 70 mg/
m3 TWA
OSHA Vacated PELs: Acetonitrile: 40 ppm TWA; 70 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear, colorless
Odor: sweetish odor - ethereal odor
pH: Not available.
Vapor Pressure: 88.8 mm Hg @ 25 deg C
Vapor Density: 1.42 (Air=1)
Evaporation Rate:5.79 (Butyl acetate=1)
Viscosity: 0.36 cP 20 deg C
Boiling Point: 82 deg C @ 760 mm Hg
Freezing/Melting Point:-45 deg C
Decomposition Temperature:> 500 deg C
Solubility: Miscible.
Specific Gravity/Density:.7810g/cm3
Molecular Formula:C2H3N
Molecular Weight:41.04
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Ignition sources, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials: Oxidizing agents, reducing agents, acids,
bases, alkali metals, fluorine, nitric acid, perchlorates, sulfuric acid, chlorosulfonic acid,
oleum, dinitrogen tetraoxide, sulfites, indium, moisture, Attacks some forms of plastics,
rubbers, and coatings., nitrating agents, N-fluoro compounds (e.g. perfluorourea +
acetonitrile), lanthanide perchlorates, iron (III) perchlorate, 2-Cyano-2-propyl nitrate,
trichlorosilane, diphenyl sulfoxide.
Hazardous Decomposition Products: Hydrogen cyanide, nitrogen oxides, carbon
monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 75-05-8: AL7700000
LD50/LC50:
CAS# 75-05-8:
Draize test, rabbit, eye: 100 uL/24H Moderate;
Inhalation, mouse: LC50 = 2693 ppm/1H;
Inhalation, rabbit: LC50 = 2828 ppm/4H;
Inhalation, rat: LC50 = 7551 ppm/8H;
Oral, mouse: LD50 = 269 mg/kg;
Oral, rabbit: LD50 = 50 mg/kg;
Oral, rat: LD50 = 2460 mg/kg;
Skin, rabbit: LD50 = >2 gm/kg;
Carcinogenicity:
CAS# 75-05-8: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: Three volunteers were exposed for 4 hours at 40, 80, or 160 ppm
acetonitrile. At 40 ppm, odor was detected, after which olfactory fatigue was noted. At
this concentratio n, 2 persons had no signs of response, including no apprec iable blood
or urinary cyanide or thiocyanate. The thi rd person experienced slight tightness in the
chest that evening. A sensation of cooling in the lungs was observed and persisted for 24
hours. Traces of urinary thiocyanate w ere recorded.
Teratogenicity: See actual entry in RTECS for complete information.
Reproductive Effects: See actual entry in RTECS for complete information.
Neurotoxicity: No information available.
Mutagenicity: See actual entry in RTECS for complete information.
Other Studies: Open irritation test: Administration onto the skin (rabbit) = 500 mg
(Mild).
Section 12 - Ecological Information
Ecotoxicity: Fish: Fathead Minnow: 1150 ppm; 24 Hr; TLm (hard water)Fish: Fathead
Minnow: 1000 mg/L; 96 Hr; TLm (soft water)Fish: Bluegill/Sunfish: 1850 mg/L; 96 Hr;
TLm (soft water)Fish: Fathead Minnow: 1640 mg/L; 96 Hr; LC50 (flow-bioassay)Fish:
Fathead Minnow: 1640 mg/L; 96 Hr; EC50 (flow-bioassay) No data available.
Environmental: Estimated Koc value = 16. Acetonitrile is expected to weakly adsorb to
most soils based on the Koc value. Volitization from soil surfaces and leaching into
ground water is expected to be significant. Estimated BCF value = 0.3. This value
indicates that acetonitrile will not significantly bioconcentrate in aquatic organisms or
adsorb to suspended solids and sediments in water. Acetonitrile is unreactive towards
photochemically-generated free radicals and direct photolysis in the gaseous phase.
Physical: No information available.
Other: Biodegradable.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 75-05-8: waste number U003 (Ignitable waste, Toxic waste).
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
ACETONITRILE
Hazard Class: 3
UN Number:
Canada TDG
ACETONITRILE
3
UN1648
Packing Group: II
UN1648
II
Additional
Info:
FLASHPOINT 6 C
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 75-05-8 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 75-05-8: Effective 10/4/82; Sunset 10/4/92
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 75-05-8: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 75-05-8: acute, chronic, flammable.
Section 313
This material contains Acetonitrile (CAS# 75-05-8, 100%),which is subject to the
reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 75-05-8 is listed as a hazardous air pollutant (HAP). This material does not contain
any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 75-05-8 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN F
Risk Phrases:
R 11 Highly flammable.
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
R 36 Irritating to eyes.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 36/37 Wear suitable protective clothing and
gloves.
WGK (Water Danger/Protection)
CAS# 75-05-8: 2
Canada - DSL/NDSL
CAS# 75-05-8 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D1B, D2B.
Canadian Ingredient Disclosure List
CAS# 75-05-8 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 75-05-8: OEL-ARAB Republic of Egypt:TWA 40 ppm (70 mg/m3);Skin
OEL-AUSTRALIA:TWA 40 ppm (70 mg/m3);STEL 60 ppm ;Skin OEL-AUSTRIA:TW
A 40 ppm (70 mg/m3) OEL-BELGIUM:TWA 40 ppm (67 mg/m3);STEL 60 ppm (10
mg/m3);Skin OEL-DENMARK:TWA 40 ppm (70 mg/m3);STEL 60 ppm (10 mg/m3)
OEL-FINLAND:TWA 40 ppm (70 mg/m3);STEL 60 ppm (10 mg/m3) OEL-FRANCE
:TWA 40 ppm (70 mg/m3) OEL-GERMANY:TWA 40 ppm (70 mg/m3) OEL-HUNGARY
:TWA 50 mg/m3;STEL 100 mg/m3;Skin JAN9 OEL-THE NETHERLANDS:TWA 40 ppm
(70 mg/m3) OEL-THE PHILIPPINES:TWA 40 ppm (70 mg/m3) OEL-RUSSIA:STE
L 10 mg/m3 OEL-SWITZERLAND:TWA 40 ppm (70 mg/m3);STEL 80 ppm ;Skin O
EL-TURKEY:TWA 40 ppm (70 mg/m3) OEL-UNITED KINGDOM:TWA 40 ppm (70 mg/
m3);STEL 60 ppm OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH
TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 4/23/1999
Revision #8 Date: 10/16/2002
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
**** MATERIAL SAFETY DATA SHEET ****
**** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****
MSDS Name: Acetylcholine chloride, 99&#37;(titr.)
Catalog Numbers:
AC400170000, AC400171000, EK 114 8816, EK114 8816, EK1148816
Synonyms:
2-(Acetyloxy)-N,N,N-trimethylethanaminium chloride
Company Identification: Fisher Scientific
1 Reagent Lane
Fairlawn, NJ 07410
For information, call: 201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
|
CAS#
|
Chemical Name
|
%
| EINECS# |
|----------------|--------------------------------------|----------|-----------|
|
60-31-1 |Acetylcholine chloride, 99% (Titr.)
| 99 (Titr | 200-468-8 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: XI
Risk Phrases: 36/37/38
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Appearance: Not available.
Caution! Irritant. Causes eye and skin irritation. Causes digestive
and respiratory tract irritation.
Target Organs: None.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and
diarrhea.
Inhalation:
Causes respiratory tract irritation.
Chronic:
No information found.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower lids. Get medical aid
immediately.
Skin:
Get medical aid. Flush skin with plenty of soap and water for at
least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do NOT induce vomiting. Allow the victim to rinse his mouth and then
to drink 2-4 cupfuls of water, and seek medical advice.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam.
Autoignition Temperature: Not available.
Flash Point: Not available.
NFPA Rating: Not published.
Explosion Limits, Lower: Not available.
Upper: Not available.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective
Equipment section. Sweep up, then place into a suitable container for
disposal.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid
ingestion and inhalation.
Storage:
Store in a cool, dry place. Keep container closed when not in use.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne
concentrations below the permissible exposure limits.
Exposure Limits
+--------------------+-------------------+-------------------+-----------------+
|
Chemical Name
|
ACGIH
|
NIOSH
|OSHA - Final PELs|
|--------------------|-------------------|-------------------|-----------------|
| Acetylcholine chlor|none listed
|none listed
|none listed
|
| ide, 99% (Titr.)
|
|
|
|
+--------------------+-------------------+-------------------+-----------------+
OSHA Vacated PELs:
Acetylcholine chloride, 99&#37; (Titr.):
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133.
Skin:
Wear appropriate protective gloves and clothing to
prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR
1910.134. Always use a NIOSH-approved respirator when
necessary.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State:
Appearance:
Odor:
pH:
Vapor Pressure:
Vapor Density:
Evaporation Rate:
Viscosity:
Boiling Point:
Freezing/Melting Point:
Decomposition Temperature:
Solubility:
Specific Gravity/Density:
Molecular Formula:
Molecular Weight:
Solid
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
150 deg C
Not available.
Not available.
Not available.
C7H16ClNO2
181.66
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents and moisture.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 60-31-1: FZ9800000
LD50/LC50:
CAS# 60-31-1: Oral, mouse: LD50 = 3 gm/kg; Oral, rat: LD50 = 2500
mg/kg.
Carcinogenicity:
Acetylcholine chloride, 99&#37; (Titr.) Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Not available.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
RCRA D-Series Maximum Concentration of Contaminants: Not listed.
RCRA D-Series Chronic Toxicity Reference Levels: Not listed.
RCRA F-Series: Not listed.
RCRA P-Series: Not listed.
RCRA U-Series: Not listed.
Not listed as a material banned from land disposal according to RCRA.
**** SECTION 14 - TRANSPORT INFORMATION ****
US DOT
No information available
IMO
Not regulated as a hazardous material.
IATA
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
Canadian TDG
No information available.
**** SECTION 15 - REGULATORY INFORMATION ****
US FEDERAL
TSCA
CAS# 60-31-1 is listed on the TSCA inventory.
Health &#38; Safety Reporting List
None of the chemicals are on the Health &#38; Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
Section 302 (RQ)
None of the chemicals in this material have an RQ.
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 60-31-1: acute.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous
Substances under the CWA.
None of the chemicals in this product are listed as Priority
Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants
under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous
by OSHA.
STATE
Not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28 After contact with skin, wash immediately with
plenty of ... (to be specified by the manufacturer).
WGK (Water Danger/Protection)
CAS# 60-31-1:
Canada
CAS# 60-31-1 is listed on Canada's DSL/NDSL List.
WHMIS: Not available.
CAS# 60-31-1 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date:
3/01/1994
Revision #2 Date:
8/24/1997
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
Material Safety Data Sheet
Ammonium hydroxide water solution, >14N NH4OH (>25% as ammonia,
NH3)
ACC# 00211
Section 1 - Chemical Product and Company Identification
MSDS Name: Ammonium hydroxide water solution, >14N NH4OH (>25% as ammonia,
NH3)
Catalog Numbers: AC205840000, AC205840010, AC205840025, AC205840050,
AC255210000, AC255210025, AC423300000, AC423300025, AC423300250,
AC423305000, S70665, S70665MF, A667-212, A669-212, A669-385LB, A669-500, A669500LC, A669-612GAL, A669C-212, A669C-212LC, A669J-500, A669P-500, A669S-212,
A669S-212E, A669S-212LC, A669S-500, A669S212EA, FLA669S-212EA, SCH1143,
58018A
Synonyms: Ammonium hydrate; Ammonia solution; Ammonia water; Aqueous
ammonia; Aqua ammonia.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
Chemical Name
Percent
EINECS/ELINCS
7664-41-7
Ammonia
>25-30
231-635-3
7732-18-5
Water
Balance
231-791-2
Hazard Symbols: C N
Risk Phrases: 34 50
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless liquid. Danger! Causes eye and skin burns. Causes digestive and
respiratory tract burns. Harmful if inhaled or swallowed.
Target Organs: Eyes, skin, mucous membranes.
Potential Health Effects
Eye: Contact with liquid or vapor causes severe burns and possible irreversible eye
damage. Lachrymator (substance which increases the flow of tears).
Skin: Causes severe skin irritation. Causes skin burns. May cause deep, penetrating
ulcers of the skin. Contact with the skin may cause staining, inflammation, and
thickening of the skin.
Ingestion: Harmful if swallowed. May cause severe and permanent damage to the
digestive tract. Causes gastrointestinal tract burns. Causes throat constriction, vomiting,
convulsions, and shock.
Inhalation: Effects may be delayed. Causes severe irritation of upper respiratory tract
with coughing, burns, breathing difficulty, and possible coma.
Chronic: Prolonged inhalation may cause respiratory tract inflammation and lung
damage. Prolonged or repeated exposure may cause corneal damage and the
development of cataracts and glaucoma.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid immediately.
Skin: In case of contact, immediately flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Get medical aid immediately.
Wash clothing before reuse.
Ingestion: If swallowed, do NOT induce vomiting. Get medical aid immediately. If victim
is fully conscious, give a cupful of water. Never give anything by mouth to an
unconscious person.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: After inhalation exposure, observe for 24 to 72 hours as pulmonary
edema may be delayed.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Use water spray to keep fire-exposed containers cool.
Contact with metals may evolve flammable hydrogen gas. Containers may explode when
heated. Approach fire from upwind to avoid hazardous vapors and toxic decomposition
products. Ammonium hydroxide itself is non-combustible. However concentrated
ammonia solutions may give off ammonia vapours. Ammonia gas is generally not
considered a serious fire or explosion hazard because ammonia/air mixtures are difficult
to ignite. A relatively high concentration of ammonia gas must be present in order for
ignition to occur. However, a large and intense energy source may cause ignition and/or
explosion in a confined space.
Extinguishing Media: Use extinguishing media most appropriate for the surrounding
fire.
Flash Point: Not available.
Autoignition Temperature: 651 deg C ( 1,203.80 deg F)
Explosion Limits, Lower:15%
Upper: 28%
NFPA Rating: (estimated) Health: 3; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Neutralize spill with a weak acid such as vinegar or acetic
acid. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills
immediately, observing precautions in the Protective Equipment section. Provide
ventilation. Approach spill from upwind.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Do not get in eyes, on skin, or on clothing. Keep container tightly closed.
Discard contaminated shoes. Do not breathe vapor. Use only with adequate ventilation.
Storage: Do not store in direct sunlight. Store in a tightly closed container. Store in a
cool, dry, well-ventilated area away from incompatible substances. Corrosives area.
Isolate from oxidizing materials and acids. Walls, floors, shelving, fittings, lighting and
ventilation systems in storage area should be made from carbon steel or stainless steel
which do not react with ammonium hydroxide.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use process enclosure, local exhaust ventilation, or other
engineering controls to control airborne levels below recommended exposure limits.
Facilities storing or utilizing this material should be equipped with an eyewash facility and
a safety shower.
Exposure Limits
Chemical Name
Ammonia
ACGIH
25 ppm TWA; 35 ppm
STEL
NIOSH
OSHA - Final PELs
25 ppm TWA; 18 mg/
m3 TWA 300 ppm IDLH
50 ppm TWA; 35 mg/
m3 TWA
Ammonium hydroxide
none listed
none listed
none listed
Water
none listed
none listed
none listed
OSHA Vacated PELs: Ammonia: No OSHA Vacated PELs are listed for this chemical.
Ammonium hydroxide: No OSHA Vacated PELs are listed for this chemical. Water: No
OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear chemical goggles and face shield.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or
European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved
respirator when necessary.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: colorless
Odor: strong odor - ammonia-like
pH: 13.6
Vapor Pressure: 557 mm Hg @ 21 deg C
Vapor Density: 0.59 (air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 27 deg C
Freezing/Melting Point:-69 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:0.89
Molecular Formula:NH4OH
Molecular Weight:35.04
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures. Ammonium
hydroxide is actually a solution of ammonia in water. Therefore the flammable properties
of ammonia apply.
Conditions to Avoid: High temperatures, confined spaces, Ammonia solutions are
corrosive to copper, zinc, aluminum and their alloys..
Incompatibilities with Other Materials: Strong oxidizing agents, acids, acrolein,
halogens, mercury, hypochlorite, silver nitrate, acrylic acid, dimethyl sulfate, silver oxide.
Hazardous Decomposition Products: Nitrogen oxides (NOx) and ammonia (NH3).
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 7664-41-7: BO0875000
CAS# 1336-21-6: BQ9625000
CAS# 7732-18-5: ZC0110000
LD50/LC50:
CAS# 7664-41-7:
Inhalation, mouse: LC50 = 4230 ppm/1H;
Inhalation, mouse: LC50 = 4600 mg/m3/2H;
Inhalation, rabbit: LC50 = 7 gm/m3/1H;
Inhalation, rat: LC50 = 2000 ppm/4H;
Inhalation, rat: LC50 = 18600 mg/m3/5M;
Inhalation, rat: LC50 = 7040 mg/m3/30M;
Skin, rat: LD50 = 112000 mg/m3/15M;
Skin, rat: LD50 = 71900 mg/m3/30M;
Skin, rat: LD50 = 4840 mg/m3/60M;
CAS# 1336-21-6:
Draize test, rabbit, eye: 250 ug Severe;
Draize test, rabbit, eye: 44 ug Severe;
Oral, rat: LD50 = 350 mg/kg;
CAS# 7732-18-5:
Oral, rat: LD50 = >90 mL/kg;
Carcinogenicity:
CAS# 7664-41-7: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 1336-21-6:
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 7732-18-5: Not listed by
ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: No data available.
Section 12 - Ecological Information
Ecotoxicity: Fish: Rainbow trout: LC50 = 0.008 mg/L; 24 Hr.; Unspecified
Fish: Fathead Minnow: LC50 = 8.2 mg/L; 96 Hr.; Unspecified
Fish: Bluegill/Sunfish: LC50 = 0.024-0.093 mg/L; 48 Hr.; Unspecified
Water flea Daphnia: EC50 =0.66 mg/L; 48 Hr.; 22 degrees C
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
AMMONIA
SOLUTIONS
Hazard Class: 8
UN Number:
Canada TDG
AMMONIA
SOLUTION
8
UN2672
Packing Group: III
UN2672
III
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 7664-41-7 is listed on the TSCA inventory.
CAS# 1336-21-6 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 7664-41-7: 100 lb final RQ; 45.4 kg final RQ CAS# 1336-21-6: 1000 lb final RQ;
454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
CAS# 7664-41-7: 500 lb TPQ
SARA Codes
CAS # 1336-21-6: acute, chronic.
Section 313
This material contains Ammonia (CAS# 7664-41-7, 25 30%),which is subject to the
reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
CAS# 7664-41-7 is listed as a Hazardous Substance under the CWA. CAS# 1336-21-6 is
listed as a Hazardous Substance under the CWA. None of the chemicals in this product
are listed as Priority Pollutants under the CWA. None of the chemicals in this product are
listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 7664-41-7 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 1336-21-6 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Massachusetts.
CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
CN
Risk Phrases:
R 34 Causes burns.
R 50 Very toxic to aquatic organisms.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 7664-41-7: 2
CAS# 1336-21-6: 2
CAS# 7732-18-5: No information available.
Canada - DSL/NDSL
CAS# 7664-41-7 is listed on Canada's DSL List.
CAS# 1336-21-6 is listed on Canada's DSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D1B, E.
Canadian Ingredient Disclosure List
CAS# 7664-41-7 is listed on the Canadian Ingredient Disclosure List.
CAS# 1336-21-6 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 7664-41-7: OEL-ARAB Republic of Egypt:TWA 25 ppm (18 mg/m3) OE
L-AUSTRALIA:TWA 25 ppm (18 mg/m3);STEL 35 ppm (27 mg/m3) OEL-AUSTRIA:
TWA 50 ppm (35 mg/m3) OEL-BELGIUM:TWA 25 ppm (17 mg/m3);STEL 35 ppm (
24 mg/m3) OEL-CZECHOSLOVAKIA:TWA 20 mg/m3;STEL 40 mg/m3 OEL-DENMARK:
TWA 25 ppm (18 mg/m3) OEL-FINLAND:TWA 25 ppm (18 mg/m3);STEL 40 ppm (
30 mg/m3) OEL-FRANCE:TWA 25 ppm (18 mg/m3);STEL 50 ppm (36 mg/m3) OE
L-GERMANY:TWA 50 ppm (35 mg/m3) OEL-HUNGARY:TWA 18 mg/m3;STEL 27 mg/m
3 OEL-INDIA:TWA 25 ppm (18 mg/m3);STEL 35 ppm (27 mg/m3) OEL-JAPAN:T
WA 25 ppm (17 mg/m3) OEL-THE NETHERLANDS:TWA 25 ppm (18 mg/m3) OEL-T
HE PHILIPPINES:TWA 50 ppm (30 mg/m3) OEL-POLAND:TWA 20 mg/m3;STEL 20
mg/m3 OEL-RUSSIA:TWA 25 ppm;STEL 20 mg/m3 OEL-SWEDEN:TWA 25 ppm (18
mg/m3);STEL 50 ppm (35 mg/m3) OEL-SWITZERLAND:TWA 25 ppm (18 mg/m3);S
TEL 50 ppm (36 mg/m3) OEL-THAILAND:TWA 50 ppm (35 mg/m3) OEL-TURKEY:
TWA 25 ppm (35 mg/m3) OEL-UNITED KINGDOM:TWA 25 ppm (18 mg/m3);STEL 3
5 ppm (27 mg/m3) OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH
TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 6/22/1999
Revision #12 Date: 7/18/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Ammonium sulfate
ACC# 01410
Section 1 - Chemical Product and Company Identification
MSDS Name: Ammonium sulfate
Catalog Numbers: AC205870000, AC205870010, AC423400000, AC423400010,
AC423400030, AC423400050, AC423400250, AC423405000, S71915, S71915ACS,
S75035, A701-3, A701-50, A702-10, A702-3, A702-500, A70250KG, A938-500, BP212212, BP212R-1, NC9059074, NC9121878, NC9155259, NC9162615, NC9179991,
NC9489144, NC9600600, NC9681931, NC9729549, NC9766751, NC9846135,
NC9955809, XXA701210LB, XXA70225KG, XXA70250KG, XXBP21225KG,
XXBP212PD25KG
Synonyms: Diammonium sulfate; Sulfuric acid, diammonium salt.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
7783-20-2
Chemical Name
Ammonium sulfate
Percent
EINECS/ELINCS
>99
231-984-1
Hazard Symbols: None listed.
Risk Phrases: None listed.
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: white solid. Caution! May cause eye, skin, and respiratory tract irritation.
Target Organs: Respiratory system, eyes, skin.
Potential Health Effects
Eye: May cause eye irritation. Causes redness and pain.
Skin: May cause skin irritation. May cause reddening of the skin.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation: May cause respiratory tract irritation. May cause respiratory difficulty and
coughing. It is generally not harmful to healthy persons if inhaled, but may con tribute to
asthma attacks or clearance problems in persons with these pre-existing pulmonary
diseases
Chronic: Prolonged or repeated skin contact may cause dermatitis.
Section 4 - First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do
NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or
water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or
other symptoms appear.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Use water spray to keep fire-exposed containers cool.
Substance is noncombustible.
Extinguishing Media: Substance is nonflammable; use agent most appropriate to
extinguish surrounding fire.
Flash Point: Not applicable.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills
immediately, observing precautions in the Protective Equipment section. Avoid generating
dusty conditions. Provide ventilation.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Use with adequate ventilation. Minimize dust generation and accumulation.
Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid
breathing dust. Do not load or store together with sodium nitrite. Ammonium sulfate can
react with sodium nitrite at temperatures as low as room temperature producing flames
or even explosions. Ammonium sulfate has a weakly acid reaction. When alkaline
substances are added, ammonia is liberated.
Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area
away from incompatible substances.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits
Chemical Name
Ammonium sulfate
ACGIH
none listed
NIOSH
OSHA - Final PELs
none listed
none listed
OSHA Vacated PELs: Ammonium sulfate: No OSHA Vacated PELs are listed for this
chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Solid
Appearance: white
Odor: odorless
pH: 5.5 (0.1M sol.)
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Negligible
Viscosity: Not applicable.
Boiling Point: Not applicable.
Freezing/Melting Point:350 deg C (dec)
Decomposition Temperature:235 deg C
Solubility: 43% at 20C.
Specific Gravity/Density:1.77
Molecular Formula:(NH4)2SO4
Molecular Weight:132.13
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Dust generation, excess heat.
Incompatibilities with Other Materials: Chlorates, nitrites, alkalis, Many metals, such
as iron and zinc, are attacked by ammonium sulfate in the presence of moisture..
Hazardous Decomposition Products: Oxides of sulfur, nitrogen oxides (NOx) and
ammonia (NH3).
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 7783-20-2: BS4500000
LD50/LC50:
CAS# 7783-20-2:
Oral, mouse: LD50 = 640 mg/kg;
Oral, mouse: LD50 = 4280 mg/kg;
Oral, rat: LD50 = 2840 mg/kg;
Oral, rat: LD50 = 4540 mg/kg;
Carcinogenicity:
CAS# 7783-20-2: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: No data available.
Section 12 - Ecological Information
Ecotoxicity: Water flea Daphnia: LC50 = 423 mg/L; 25 Hr; Unspecified
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
Not
regulated
Hazard Class:
UN Number:
Packing Group:
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 7783-20-2 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Canada TDG
No information
available.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 7783-20-2: acute.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 7783-20-2 can be found on the following state right to know lists: New Jersey,
Pennsylvania, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 7783-20-2: 1
Canada - DSL/NDSL
CAS# 7783-20-2 is listed on Canada's DSL List.
Canada - WHMIS
This product does not have a WHMIS classification.
Canadian Ingredient Disclosure List
CAS# 7783-20-2 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
Section 16 - Additional Information
MSDS Creation Date: 7/19/1999
Revision #3 Date: 3/31/2004
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Safety (MSDS) data for benzalkonium chloride
General
Synonyms: parasterol, alkyl benzyl dimethylammonium chloride, alkyl dimethyl
benzylammonium chloride, benirol, cequartryl, drapolene, enuclene, germitol,
gesminol, rodalon, ammonyx, zephiran chloride, various further trade names
Use: medical disinfectant
Molecular formula: (mixture)
CAS No: 8001-54-5
EC No:
Physical data
Appearance: white or light yellow/grey solid, or colourless aqueous solution
Melting point:
Boiling point:
Vapour density:
Vapour pressure:
Specific gravity: 0.98
Flash point: 250 C
Explosion limits:
Autoignition temperature:
Stability
Stable. Incompatible with strong oxidizing agents, moisture. Hygroscopic
Toxicology
Corrosive, toxic - causes burns. Harmful by inhalation, ingestion and through skin
contact. May cause reproductive defects. May act as a mutagen.
Toxicity data
(The meaning of any abbreviations which appear in this section is given here.)
ORL-RAT LD50 240 mg kg-1
ORL-WMN lowest published toxic dose 266 mg kg-1
IPN-RAT LD50 14.5 mg kg-1
Risk phrases
(The meaning of any risk phrases which appear in this section is given here.)
R21 R22 R34.
Transport information
(The meaning of any UN hazard codes which appear in this section is given here.)
UN Major hazard class 8. Packing group III
Personal protection
Safety glasses, adequate ventilation, gloves.
Safety phrases
(The meaning of any safety phrases which appear in this section is given here.)
S26 S28b S36 S37 S39
[Return to Physical & Theoretical Chemistry Lab. Safety home page.]
This information was last updated on September 2, 2003. We have tried to make it as
accurate and useful as possible, but can take no responsibility for its use, misuse, or
accuracy. We have not verified this information, and cannot guarantee that it is up-to-date.
Material Safety Data Sheet
Calcium Phosphate Tribasic
ACC# 45339
Section 1 - Chemical Product and Company Identification
MSDS Name: Calcium Phosphate Tribasic
Catalog Numbers: C127-500, C133-212, C133-500
Synonyms: Tricalcium phosphate; Calcium phosphate Ca3(PO4)2; Calcium phosphate,
tribasic; Tricalcium orthophosphate.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
7758-87-4
Chemical Name
Phosphoric acid, calcium salt (2:3)
Percent
EINECS/ELINCS
100
231-840-8
Hazard Symbols: None listed.
Risk Phrases: None listed.
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: white. Caution! May cause eye and skin irritation. May cause respiratory
tract irritation.
Target Organs: No data found.
Potential Health Effects
Eye: May cause eye irritation.
Skin: May cause skin irritation. The toxicological properties of this material have not
been fully investigated.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The
toxicological properties of this substance have not been fully investigated.
Inhalation: May cause respiratory tract irritation. The toxicological properties of this
substance have not been fully investigated.
Chronic: No information found.
Section 4 - First Aid Measures
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the
upper and lower eyelids. Get medical aid.
Skin: Flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash
clothing before reuse.
Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do
NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or
water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or
other symptoms appear.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Substance is noncombustible; use agent most appropriate to
extinguish surrounding fire.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Reduce airborne dust and prevent scattering by moistening with water. Clean up spills
immediately, observing precautions in the Protective Equipment section. Avoid generating
dusty conditions. Provide ventilation.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Wash hands before eating. Use with
adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly
closed. Avoid ingestion and inhalation.
Storage: Keep container closed when not in use. Store in a tightly closed container.
Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits
Chemical Name
NIOSH
OSHA - Final PELs
Phosphoric acid, calcium
none listed
salt (2:3)
none listed
none listed
Hydroxylapatite Ca5(OH)
none listed
(PO4)3
none listed
none listed
none listed
none listed
Calcium hydroxide
phosphate (Ca5(OH)
(PO4)3)
ACGIH
none listed
OSHA Vacated PELs: Phosphoric acid, calcium salt (2:3): No OSHA Vacated PELs are
listed for this chemical. Hydroxylapatite Ca5(OH)(PO4)3: No OSHA Vacated PELs are
listed for this chemical. Calcium hydroxide phosphate (Ca5(OH)(PO4)3): No OSHA
Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or
European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved
respirator when necessary.
Section 9 - Physical and Chemical Properties
Physical State: Solid
Appearance: white
Odor: odorless
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:1670 deg C
Decomposition Temperature:Not available.
Solubility: Insoluble.
Specific Gravity/Density:3.14
Molecular Formula:Ca10O25P6.H2O
Molecular Weight:1004.7
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Dust generation, excess heat.
Incompatibilities with Other Materials: No information found..
Hazardous Decomposition Products: Phosphine, oxides of phosphorus, irritating and
toxic fumes and gases, calcium oxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 7758-87-4 unlisted.
CAS# 1306-06-5: MY8434000
CAS# 12167-74-7 unlisted.
LD50/LC50:
Not available.
CAS# 1306-06-5:
Oral, mouse: LD50 = >99500 mg/kg;
Oral, rat: LD50 = >25350 mg/kg;
CAS# 12167-74-7:
Carcinogenicity:
CAS# 7758-87-4: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 1306-06-5:
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 12167-74-7: Not listed by
ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: No data available.
Section 12 - Ecological Information
Ecotoxicity: No data available. No information available.
Environmental: Phosphates promote the eutrophication of lakes and other bodies of
water.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
No
information
available.
Hazard Class:
UN Number:
Packing Group:
Section 15 - Regulatory Information
US FEDERAL
Canada TDG
No information
available.
TSCA
CAS# 7758-87-4 is listed on the TSCA inventory.
CAS# 1306-06-5 is listed on the TSCA inventory.
CAS# 12167-74-7 is not listed on the TSCA inventory. It is for research and development
use only.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 7758-87-4 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 1306-06-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 12167-74-7 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 7758-87-4: 0
CAS# 1306-06-5: 0
CAS# 12167-74-7: 0
Canada - DSL/NDSL
CAS# 7758-87-4 is listed on Canada's DSL List.
CAS# 1306-06-5 is listed on Canada's DSL List.
CAS# 12167-74-7 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of Not controlled..
Canadian Ingredient Disclosure List
Exposure Limits
Section 16 - Additional Information
MSDS Creation Date: 9/02/1997
Revision #5 Date: 8/28/2002
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Carbowax PEG 400
ACC# 19121
Section 1 - Chemical Product and Company Identification
MSDS Name: Carbowax PEG 400
Catalog Numbers: NC9080833, NC9081979, NC9091272, P167-1, P167N119,
XXP1671218.2LI, XXP167N118.2LI
Synonyms: Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-; Polyethylene
glycol; Poly(ethylene oxide); Poly(oxyethylene) glycol; Ethylene oxide, homopolymer.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
25322-68-3
Chemical Name
Polyethylene glycol
Percent
EINECS/ELINCS
100
unlisted
Hazard Symbols: None listed.
Risk Phrases: None listed.
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: clear liquid. This is expected to be a low hazard for usual industrial handling.
Good laboratory procedures are recommended when handling this compound.
Target Organs: None.
Potential Health Effects
Eye: May cause mild eye irritation.
Skin: Low hazard for usual industrial handling.
Ingestion: Causes gastrointestinal irritation with nausea, vomiting and diarrhea. Low
hazard for usual industrial handling.
Inhalation: Low hazard for usual industrial handling.
Chronic: Prolonged exposure may cause eye irritation.
Section 4 - First Aid Measures
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the
upper and lower eyelids. If irritation develops, get medical aid.
Skin: Flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash
clothing before reuse.
Ingestion: Never give anything by mouth to an unconscious person. Do NOT induce
vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Wash mouth out with water. Get medical aid if irritation or symptoms occur.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or
other symptoms appear.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion.
Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam.
Flash Point: 176 deg C ( 348.80 deg F)
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 0; Flammability: 1; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Avoid contact with eyes, skin, and clothing.
Keep container tightly closed.
Storage: No special precautions indicated. Store at room temperature.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Good general ventilation should be sufficient to control airborne
levels.
Exposure Limits
Chemical Name
Polyethylene glycol
ACGIH
none listed
NIOSH
OSHA - Final PELs
none listed
none listed
OSHA Vacated PELs: Polyethylene glycol: No OSHA Vacated PELs are listed for this
chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Glove protection is not normally required.
Clothing: Protective garments not normally required.
Respirators: Respirator protection is not normally required.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear
Odor: mild odor
pH: 4.5-7.5 (5% soln)
Vapor Pressure: Low
Vapor Density: Not available.
Evaporation Rate:0.01 (Butyl acetate=1)
Viscosity: 6.8-8.0 cS@99C
Boiling Point: Not available.
Freezing/Melting Point:8 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:1.128 @ 25°C
Molecular Formula:C2H4OnH2O
Molecular Weight:380-420
Section 10 - Stability and Reactivity
Chemical Stability: Stable.
Conditions to Avoid: No specific conditions to avoid noted.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 25322-68-3: TQ3500000; TQ3520000; TQ3560000; TQ3580000; TQ3600000;
TQ3610000; TQ3620000; TQ3630000; TQ3650000; TQ3675000; TQ3700000;
TQ3800000; TQ3850000; TQ4025000; TQ4026000; TQ4027000; TQ4028000;
TQ4030000; TQ4040000; TQ4041000; TQ4050000; TQ4070000; TQ4100000;
TQ4105000; TQ4110000; TQ4950000; TQ5090000; TR1579850; ZD2465300
LD50/LC50:
CAS# 25322-68-3:
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, eye: 100 uL Mild;
Draize test, rabbit, eye: 500 mg Mild;
Draize test, rabbit, eye: 500 mg Mild;
Draize test, rabbit, eye: 500 mg Mild;
Draize test, rabbit, eye: 500 mg Mild;
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, eye: 500 mg Mild;
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, skin: 500 mg/24H Mild;
Draize test, rabbit, skin: 500 mg/24H Mild;
Draize test, rabbit, skin: 500 mg Mild;
Oral, mouse: LD50 = 34 gm/kg;
Oral, mouse: LD50 = 31 gm/kg;
Oral, mouse: LD50 = 28915 mg/kg;
Oral, mouse: LD50 = 36 gm/kg;
Oral, rabbit: LD50 = 17300 mg/kg;
Oral, rabbit: LD50 = 76 gm/kg;
Oral, rabbit: LD50 = 14 gm/kg;
Oral, rabbit: LD50 = 17300 mg/kg;
Oral, rabbit: LD50 = 26800 mg/kg;
Oral, rabbit: LD50 = 19 gm/kg;
Oral, rabbit: LD50 = 28900 mg/kg;
Oral,
Carcinogenicity:
CAS# 25322-68-3: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No data available.
Teratogenicity: No data available.
Reproductive Effects: No data available.
Neurotoxicity: No data available.
Mutagenicity: No data available.
Other Studies: No data available.
Section 12 - Ecological Information
Ecotoxicity: Fish: Goldfish: LC50 = >5000 mg/L; 24 Hr.; Unspecified
Bacteria: Phytobacterium phosphoreum: EC50 =100,000 mg/L; 15 minutes; Microtox test
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
No
information
available.
Hazard Class:
UN Number:
Packing Group:
Section 15 - Regulatory Information
Canada TDG
No information
available.
US FEDERAL
TSCA
CAS# 25322-68-3 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 25322-68-3.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 25322-68-3 can be found on the following state right to know lists: Minnesota.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 25322-68-3: 1
Canada - DSL/NDSL
CAS# 25322-68-3 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of Not controlled..
Canadian Ingredient Disclosure List
Exposure Limits
Section 16 - Additional Information
MSDS Creation Date: 7/01/1999
Revision #6 Date: 3/04/2004
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Chloroform
ACC# 95979
Section 1 - Chemical Product and Company Identification
MSDS Name: Chloroform
Catalog Numbers: AC158210000, AC158210010, AC158210025, AC158210250,
AC167730000, AC167730010, AC167730025, AC167735000, AC232090000,
AC232090010, AC232090025, AC268320000, AC268320010, AC268320025,
AC326670000, AC326670010, AC326670025, AC326820000, AC326820010,
AC326821000, AC326822500, AC364320000, AC364320010, AC364321000,
AC404630000, AC404635000, AC423550000, AC423550040, AC423550250,
AC423555000, AC610030040, AC610281000, S79960, S799601, S79960HPLC1,
S79960SPEC1, S79960SPEC2, S79969ACS1, S79969ACS2, BP1145-1, BP2606-100,
C294-1, C294-4, C295-20, C295-4, C295S-4, C297-4, C2974LC, C297POP19,
C297POP200, C297POP50, C297RS115, C297RS28, C297SS115, C297SS19, C297SS200,
C297SS28, C297SS50, C298-1, C298-20, C298-200, C298-4, C298-500, C29820LC,
C298FB115, C298FB19, C298FB200, C298FB50, C298J1, C298POP19, C298POP200,
C298POP50, C298POPB19, C298POPB200, C298POPB50, C298RB115, C298RB200,
C298RS115, C298RS19, C298RS200, C298RS28, C298RS50, C298S-4, C298SK-4,
C298SS19, C574-1, C574-4, C574SK-4, C603-4, C606-1, C606-4, C606POP19,
C606POP200, C606POP50, C606RS115, C606RS28, C606SK-1, C606SK-4, C606SS115,
C606SS19, C606SS200, C606SS28, C606SS50, C607-1, C607-4, C607J4, C607SK-1,
C607SK-4, NC9002591, NC9543674
Synonyms: Formyl trichloride; Methane trichloride; Methenyl trichloride; Methyl
trichloride; Trichloroform; Trichloromethane.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
67-66-3
Chemical Name
Chloroform
Hazard Symbols: XN
Percent
EINECS/ELINCS
99+
200-663-8
Risk Phrases: 22 38 40 48/20/22
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: clear, colorless liquid. May cause central nervous system depression. May
cause cardiac disturbances. May cause cancer based on animal studies. This substance
has caused adverse reproductive and fetal effects in animals. May be harmful if
swallowed. Caution! Causes eye and skin irritation. Light sensitive. Causes respiratory
tract irritation.
Target Organs: Blood, kidneys, heart, central nervous system, liver, cardiovascular
system, excretory system, reproductive system.
Potential Health Effects
Eye: Causes moderate eye irritation. Contact with liquid causes immediate burning pain,
tearing, and reddening of the conjunctiva.
Skin: Causes mild skin irritation. Absorption of liquid through intact skin is possible and
may cause sys temic poisoning if contact with liquid is prolonged.
Ingestion: Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May
cause liver damage. May cause cardiac disturbances. Aspiration of material into the lungs
may cause chemical pneumonitis, which may be fatal. Possible aspiration hazard. May
cause hallucinations and distorted perceptions.
Inhalation: Inhalation of high concentrations may cause central nervous system effects
characterized by nausea, headache, dizziness, unconsciousness and coma. May cause
cardiac sensitization and possible failure. Inhalation of large amounts may cause
respiratory stimulation, followed by respiratory depression, convulsions and possible
death due to respiratory paralysis. May be absorbed through the lungs. Causes irritation
of the mucous membrane and upper respiratory tract.
Chronic: Possible cancer hazard based on tests with laboratory animals. Prolonged or
repeated skin contact may cause defatting and dermatitis. May cause reproductive and
fetal effects. Effects may be delayed. Laboratory experiments have resulted in mutagenic
effects. Toxicity may be increased by exposure to alcohol, steroids, and ketones.
Prolonged exposure may cause liver, kidney, and heart damage.
Section 4 - First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. Get medical aid
immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air
immediately. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen.
Notes to Physician: Causes cardiac sensitization to endogenous catelcholamines which
may lead to cardiac arrhythmias. Do NOT use adrenergic agents such as epinephrine or
pseudoepinephrine. Persons with liver, kidney, or central nervous system diseases may
be at increased risk from exposure to this product. Alcoholic beverage consumption may
enhance the toxic effects of this substance. Effects may be delayed.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Use water spray to keep fire-exposed containers cool.
Substance is nonflammable. Vapors may be heavier than air. They can spread along the
ground and collect in low or confined areas. Containers may explode when heated. Noncombustible, substance itself does not burn but may decompose upon heating to produce
corrosive and/or toxic fumes. Non-combustible, substance itself does not burn but may
decompose upon heating to produce irritating, corrosive and/or toxic fumes. Approach
fire from upwind to avoid hazardous vapors and toxic decomposition products. Not
combustible, but if involved in a fire, decomposes to produce hydrogen chloride.
Extinguishing Media: Use extinguishing media most appropriate for the surrounding
fire.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Avoid runoff into storm sewers and ditches which lead to
waterways. Clean up spills immediately, observing precautions in the Protective
Equipment section. Provide ventilation. Approach spill from upwind.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Use only in a well-ventilated area. Avoid contact with eyes, skin, and
clothing. Do not breathe dust, vapor, mist, or gas. Do not ingest or inhale. Store
protected from light.
Storage: Do not store in direct sunlight. Store in a cool, dry, well-ventilated area away
from incompatible substances. Keep away from acids. Do not store near alkaline
substances. Separate from strong mineral acids.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name
Chloroform
ACGIH
10 ppm TWA
NIOSH
OSHA - Final PELs
500 ppm IDLH
50 ppm Ceiling; 240 mg/
m3 Ceiling
OSHA Vacated PELs: Chloroform: 2 ppm TWA; 9.78 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear, colorless
Odor: sweet, fruity odor - ethereal odor
pH: Not available.
Vapor Pressure: 160 mm Hg @ 20 deg C
Vapor Density: 4.12 (Air=1)
Evaporation Rate:11.6 (Butyl acetate=1)
Viscosity: 0.58 cps @ 20 deg C
Boiling Point: 60.5-61.5 deg C
Freezing/Melting Point:-63 deg C
Decomposition Temperature:Not available.
Solubility: Slightly soluble.
Specific Gravity/Density:1.492 (Water=1)
Molecular Formula:CHCl3
Molecular Weight:119.366
Section 10 - Stability and Reactivity
Chemical Stability: Stable at room temperature in closed containers under normal
storage and handling conditions. Light sensitive.
Conditions to Avoid: High temperatures, incompatible materials, light.
Incompatibilities with Other Materials: Acetone + alkali, disilane, nitrogen tetroxide,
perchloric acid + phosphorus pentoxide, potassium tert-butoxide, sodium methylate,
dinitrogen tetraoxide, fluorine, chemically active metals, triisopropylphosphine, caustics
(e.g. ammonia, ammonium hydroxide, calcium hydroxide, potassium hydroxide, sodium
hydroxide), powdered aluminum, powdered magnesium, alkali metals, sodium hydroxide
+ methanol.
Hazardous Decomposition Products: Hydrogen chloride, irritating and toxic fumes
and gases, carbon dioxide, chlorine, phosgene gas.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 67-66-3: FS9100000
LD50/LC50:
CAS# 67-66-3:
Draize test, rabbit, eye: 148 mg;
Draize test, rabbit, eye: 20 mg/24H Moderate;
Draize test, rabbit, skin: 500 mg/24H Mild;
Inhalation, rat: LC50 = 47702 mg/m3/4H;
Oral, mouse: LD50 = 36 mg/kg;
Oral, rat: LD50 = 695 mg/kg;
Skin, rabbit: LD50 = >20 gm/kg;
Carcinogenicity:
CAS# 67-66-3:
ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to humans
California: carcinogen, initial date 10/1/87
NIOSH: potential occupational carcinogen
NTP: Suspect carcinogen
OSHA: Possible Select carcinogen
IARC: Group 2B carcinogen
Epidemiology: Oral, rat: TDLo = 13832 mg/kg/2Y-C (Tumorigenic - Carcinogen ic by
RTECS criteria - Blood - leukemia).; Oral, mouse: TDLo = 127 gm/kg/92W-I
(Tumorigenic - Carcinogenic by RTECS criteria - Liver - tumors).; Oral, rat: TD = 98 gm/
kg/78W-I (Tumorigenic - neoplastic by RTECS criteria - Kidney, Ureter, Bladder - Kidney
tumors and Endocrine - thyroid tumors).; Oral, mouse: TD = 18 gm/kg/17W-I
(Tumorigenic - neoplastic by RTECS criteria - Liver - tumor s).;
Teratogenicity: Oral, rat: TDL0 = 1260 mg/kg (female 6-15 day(s) after conception)
Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Specific
Developmental Abnormalities - musculoskeletal system.; Inhalation, rat: TCLo = 100
ppm/7H (female 6-15 day(s) after conception) Specific Developmental Abnormalities gastrointestinal system and homeostasis.; Inhalation, mouse: TCLo = 100 ppm/7H
(female 8-15 day(s) after conception) Specific Developmental Abnormalities - craniofacial
(including nose and tongue).
Reproductive Effects: Inhalation, rat: TCLo = 30 ppm/7H (female 6-15 day(s) after
conception) Fertility - other measures of fertility.; Inhalation, rat: TCLo = 300 ppm/7H
(female 6-15 day(s) after conception) Fertility - female fertility index (e.g. # females
pregnant per # sperm positive females; # females pregnant per # females mated) and
post-implantation mortality (e.g. dead and/or resorbed implants per total number of
implants).
Neurotoxicity: No information available.
Mutagenicity: DNA Inhibition: Human, HeLa cell = 19 mmol/L.; Sister Chromatid
Exchange: Human, Lymphocyte = 10 mmol/L.; Micronucleus Test: Oral, rat = 4 mmol/
kg.; Unscheduled DNA Synthesis: Oral, rat = 1 gm/kg.; Sister Chromatid Exchange:
Hamster, Embryo = 100 umol/L.
Other Studies: Open irritation test: Administration onto the skin (rabbit) 10 mg/24H
(Mild). Standard Draize Test: Administratio n onto the skin (rabbit) = 500 mg/24H (Mild).
Standard D raize Test: Administration into the eye (rabbit) = 20 mg /24H (Moderate).
Section 12 - Ecological Information
Ecotoxicity: Fish: Channel catfish: LC50 = 75 ppm; 96 Hr; UnspecifiedFish: Rainbow
trout: LC50 = 43.8 mg/L; 96 Hr; Static bioassayFish: Fathead Minnow: LC50 = 129.0 mg/
L; 96 Hr; Static bioassay (pH = 7.6-8.3)Fish: Bluegill/Sunfish: LC50 = 100.0 mg/L; 96
Hr; Static bioassayWater flea Daphnia: EC50 = 28.9 mg/L; 48 Hr; Static bioassay The
majority of the environmental releases from industrial uses are to the atmosphere;
releases to water and land will be primarily lost by evaporation and will end up in the
atmosphere. Release to the atmosphere may be transported long distances and will
photodegrade with a half-life of a few months. Spills and other releases on land will also
leach into the groundwater where it will reside for long periods of time.
Environmental: Chloroform will not be expected to bioconcentrate into the food chain
but contamination of food is likely due to its use as an extractant and its presence in
drinking water.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 67-66-3: waste number U044.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
CHLOROFORM
Hazard Class: 6.1
UN Number:
Canada TDG
CHLOROFORM
6.1(9.2)
UN1888
Packing Group: III
UN1888
III
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 67-66-3 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 67-66-3: Effective 6/1/87; Sunset 6/1/97
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 67-66-3: 10 lb final RQ; 4.54 kg final RQ
SARA Section 302 Extremely Hazardous Substances
CAS# 67-66-3: 10000 lb TPQ
SARA Codes
CAS # 67-66-3: acute, chronic.
Section 313
This material contains Chloroform (CAS# 67-66-3, 99%),which is subject to the reporting
requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 67-66-3 is listed as a hazardous air pollutant (HAP). This material does not contain
any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 67-66-3 is listed as a Hazardous Substance under the CWA. CAS# 67-66-3 is listed
as a Priority Pollutant under the Clean Water Act. CAS# 67-66-3 is listed as a Toxic
Pollutant under the Clean Water Act.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 67-66-3 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
The following statement(s) is(are) made in order to comply with the California
Safe Drinking Water Act: WARNING: This product contains Chloroform, a chemical
known to the state of California to cause cancer. California No Significant Risk Level:
CAS# 67-66-3: 20 æg/day NSRL (oral); 40 æg/day NSRL (inhalation)
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 22 Harmful if swallowed.
R 38 Irritating to skin.
R 40 Limited evidence of a carcinogenic effect.
R 48/20/22 Harmful : danger of serious damage to
health by prolonged exposure through inhalation and if
swallowed.
Safety Phrases:
S 36/37 Wear suitable protective clothing and
gloves.
WGK (Water Danger/Protection)
CAS# 67-66-3: 3
Canada - DSL/NDSL
CAS# 67-66-3 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D2A, D1B.
Canadian Ingredient Disclosure List
CAS# 67-66-3 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 67-66-3: OEL-ARAB Republic of Egypt:TWA 10 ppm (50 mg/m3) OELAUSTRALIA:TWA 10 ppm (50 mg/m3);Carcinogen OEL-AUSTRIA:TWA 10 ppm (50
mg/m3) OEL-BELGIUM:TWA 10 ppm (49 mg/m3);Carcinogen JAN9 OEL-CZECHO
SLOVAKIA:TWA 10 mg/m3;STEL 20 mg/m3 OEL-DENMARK:TWA 2 ppm (10 mg/m3);
Carcinogen OEL-FINLAND:TWA 10 ppm (50 mg/m3);STEL 20 ppm;Skin;CAR OE
L-FRANCE:TWA 5 ppm (25 mg/m3);STEL 50 ppm (250 mg/m3);CAR OEL-GERMANY
:TWA 10 ppm (50 mg/m3);Carcinogen JAN9 OEL-HUNGARY:STEL 10 mg/m3 OEL
-INDIA:TWA 10 ppm (50 mg/m3);Carcinogen OEL-JAPAN:TWA 50 ppm (240 mg/
m3);Carcinogen OEL-THE NETHERLANDS:TWA 10 ppm (50 mg/m3) OEL-THE PHI
LIPPINES:TWA 50 ppm (240 mg/m3) OEL-POLAND:TWA 50 mg/m3 OEL-RUSSIA:T
WA 50 ppm OEL-SWEDEN:TWA 2 ppm (10 mg/m3);STEL 5 ppm (25 mg/m3);CAR
OEL-SWITZERLAND:TWA 10 ppm (50 mg/m3);STEL 20 ppm (100 mg/m3) OEL-THA
ILAND:TWA 50 ppm (240 mg/m3) OEL-TURKEY:TWA 50 ppm (240 mg/m3) OEL-U
NITED KINGDOM:TWA 2 ppm (9.9 mg/m3);Skin OEL IN BULGARIA, COLOMBIA, J
ORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM c
heck ACGIH TLV
Section 16 - Additional Information
MSDS Creation Date: 6/09/1999
Revision #8 Date: 4/13/2004
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Collodion, Flexible
ACC# 00463
Section 1 - Chemical Product and Company Identification
MSDS Name: Collodion, Flexible
Catalog Numbers: AC405350000, AC405355000, C-409
Synonyms: Nitrocellulose; Cellulose nitrate; Guncotton; Nitrocotton; Pyroxylin
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
Chemical Name
Percent
EINECS/ELINCS
60-29-7
Ethyl Ether
70-75
200-467-2
64-17-5
Ethanol
20-25
200-578-6
4-8
unlisted
5
232-293-8
9004-70-0
Nitrocellulose
8001-79-4
Castor Oil
Hazard Symbols: XI F
Risk Phrases: 11 36/37/38
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: clear, colorless liquid. Flash Point: -45 deg C. Danger! Extremely
flammable liquid. Causes eye and skin irritation. May cause central nervous system
depression. May cause blood abnormalities. May form explosive peroxides. Hygroscopic
(absorbs moisture from the air). Air sensitive. Light sensitive. Aspiration hazard if
swallowed. Can enter lungs and cause damage. May be harmful if swallowed. May be
habit forming. May be harmful if absorbed through the skin. May cause liver and kidney
damage. May cause reproductive and fetal effects. Causes respiratory tract irritation.
Target Organs: Kidneys, central nervous system, liver, respiratory system, skin.
Potential Health Effects
Eye: Causes moderate eye irritation. Causes redness and pain.
Skin: May be harmful if absorbed through the skin. Causes severe skin irritation and
possible burns.
Ingestion: Aspiration hazard. Symptoms may include: headache, excitement, fatigue,
nausea, vomiting, stupor, and coma. May cause central nervous system depression,
characterized by excitement, followed by headache, dizziness, drowsiness, and nausea.
Advanced stages may cause collapse, unconsciousness, coma and possible death due to
respiratory failure. May cause digestive tract disturbances. Aspiration of material into the
lungs may cause chemical pneumonitis, which may be fatal. May be harmful if swallowed.
Inhalation: Inhalation of high concentrations may cause central nervous system effects
characterized by nausea, headache, dizziness, unconsciousness and coma. May cause
respiratory tract irritation. Vapors may cause dizziness or suffocation. May cause
respiratory failure possibly leading to death. May cause seizures and blood abnormalities.
May be absorbed through the lungs. Causes irritation of the mucous membrane and
upper respiratory tract. Inhalation may cause irritation of the nose and throat, vomiting,
irregular respiration, dizziness, drowsiness, unconsciousness and possible death due to
respiratory paralysis.
Chronic: Prolonged or repeated skin contact may cause defatting and dermatitis.
Prolonged or repeated exposure can cause psychic abnormalities such as anxiety,
depression and excitability. Laboratory experiments have resulted in mutagenic effects.
May cause kidney damage. Prolonged exposure to high vapor concentrations may cause
eye injury.
Section 4 - First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes. Wash clothing before
reuse.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. Possible
aspiration hazard. Get medical aid immediately.
Inhalation: Remove from exposure and move to fresh air immediately. If breathing is
difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If
breathing has ceased apply artificial respiration using oxygen and a suitable mechanical
device such as a bag and a mask.
Notes to Physician: Persons with kidney disease, chronic respiratory disease, liver
disease, or skin disease may be at increased risk from exposure to this substance.
Alcoholic beverage consumption may enhance the toxic effects of this substance. Treat
symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Vapors may form an explosive mixture with air. Vapors can travel to a source of ignition
and flash back. During a fire, irritating and highly toxic gases may be generated by
thermal decomposition or combustion. Extremely flammable. Material will readily ignite at
room temperature. Use water spray to keep fire-exposed containers cool. Water may be
ineffective. Material is lighter than water and a fire may be spread by the use of water.
Containers may explode in the heat of a fire. May form explosive peroxides. Vapors may
be heavier than air. They can spread along the ground and collect in low or confined
areas. Will be easily ignited by heat, sparks or flame. May re-ignite after fire is
extinguished.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. Water may be ineffective. Water may spread fire. If water is the
only media available, use in flooding amounts. For large fires, use water spray, fog or
alcohol-resistant foam. Do NOT use straight streams of water. Cool containers with
flooding quantities of water until well after fire is out.
Flash Point: -45 deg C ( -49.00 deg F)
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 3; Instability: 1
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Scoop up with a nonsparking tool, then place into a suitable container for disposal.
Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material
such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust.
Use a spark-proof tool. Provide ventilation. Place under an inert atmosphere. A vapor
suppressing foam may be used to reduce vapors.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Use only in a well-ventilated area. Ground and bond containers when
transferring material. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on
skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and
can be dangerous. Take precautionary measures against static discharges. Keep
container tightly closed. Keep away from heat, sparks and flame. Do not ingest or inhale.
Store protected from light. Handle under an inert atmosphere. Store protected from air.
If peroxide formation is suspected, do not open or move container. Do not pressurize,
cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open
flames.
Storage: Keep away from heat, sparks, and flame. Keep away from heat and flame.
Keep away from sources of ignition. Do not store near combustible materials. Do not
store in direct sunlight. Store in a tightly closed container. Keep container closed to
prevent drying out. Store in a cool, dry, well-ventilated area away from incompatible
substances. Flammables-area. Keep refrigerated. (Store below 4°C/39°F.) Do not expose
to air. Store protected from moisture. Store protected from light. Store under an inert
atmosphere. Keep away from oxidizing agents.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility and a safety shower.
Use adequate general or local exhaust ventilation to keep airborne concentrations below
the permissible exposure limits.
Exposure Limits
Chemical Name
Ethyl Ether
Ethanol
ACGIH
400 ppm TWA; 500
ppm STEL
1000 ppm TWA
NIOSH
OSHA - Final PELs
1900 ppm IDLH
400 ppm TWA; 1200
mg/m3 TWA
1000 ppm TWA; 1900
mg/m3 TWA 3300 ppm
IDLH
1000 ppm TWA; 1900
mg/m3 TWA
Nitrocellulose
none listed
none listed
none listed
Castor Oil
none listed
none listed
none listed
OSHA Vacated PELs: Ethyl Ether: 400 ppm TWA; 1200 mg/m3 TWA Ethanol: 1000 ppm
TWA; 1900 mg/m3 TWA Nitrocellulose: No OSHA Vacated PELs are listed for this
chemical. Castor Oil: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear, colorless
Odor: ether odor.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: 2.6
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: Not available.
Specific Gravity/Density:Not available.
Molecular Formula:Not available.
Molecular Weight:Not available.
Section 10 - Stability and Reactivity
Chemical Stability: Prolonged exposure to air and sunlight may form unstable
peroxides.
Conditions to Avoid: Incompatible materials, light, ignition sources, exposure to air,
excess heat, strong acids, exposure to moist air or water, oxidizers.
Incompatibilities with Other Materials: Strong oxidizing agents, oxidizing agents,
reducing agents, acids, bases, bromine trifluoride, chlorine trifluoride, halogens, nitric
acid, permanganates, silver perchlorate, sodium peroxide, sulfur, sulfuric acid, hydrogen
peroxide, ozone, bromine, chromyl chloride, fluorine nitrate, nitrosyl perchlorate, bromine
pentafluoride, perchloric acid, chromic anhydride, interhalogens, chlorine, uranyl nitrate,
moisture, air, iodine heptafluoride, boron triazide, wood pulp extracts + heat, acetyl
peroxide, bromoazide, potassium peroxide, triethyl or trimethyl aluminum + air, lithium
aluminum hydride, thiotriazyl perchlorate, nitryl perchlorate, permanganic acid,
peroxodisulfuric acid, iodine (VII) oxide, sulfonyl chloride, liquid air.
Hazardous Decomposition Products: Hydrogen cyanide, carbon monoxide, oxides of
nitrogen, irritating and toxic fumes and gases, carbon dioxide, peroxides.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 60-29-7: KI5775000
CAS# 64-17-5: KQ6300000
CAS# 9004-70-0: QW0970000
CAS# 8001-79-4: FI4100000
LD50/LC50:
CAS# 60-29-7:
Draize test, rabbit, eye: 100 mg Moderate;
Inhalation, mouse: LC50 = 31000 ppm/30M;
Oral, rat: LD50 = 1215 mg/kg;
Skin, rabbit: LD50 = >20 mL/kg;
CAS# 64-17-5:
Draize test, rabbit, eye: 500 mg Severe;
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, skin: 20 mg/24H Moderate;
Inhalation, mouse: LC50 = 39 gm/m3/4H;
Inhalation, rat: LC50 = 20000 ppm/10H;
Oral, mouse: LD50 = 3450 mg/kg;
Oral, rabbit: LD50 = 6300 mg/kg;
Oral, rat: LD50 = 7060 mg/kg;
Oral, rat: LD50 = 9000 mg/kg;
CAS# 9004-70-0:
Oral, mouse: LD50 = >5 gm/kg;
Oral, rat: LD50 = >5 gm/kg;
CAS# 8001-79-4:
Draize test, rabbit, eye: 500 mg Mild;
Draize test, rabbit, skin: 100 mg/24H Severe;
Carcinogenicity:
CAS# 60-29-7: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 64-17-5: Not
listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 9004-70-0: Not listed by ACGIH,
IARC, NIOSH, NTP, or OSHA. CAS# 8001-79-4: Not listed by ACGIH, IARC, NIOSH, NTP,
or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: CAS# 60-29-7: DNA Repair: Escherichia coli = 35670 ug/well/16H.; DNA
Inhibition: Mouse, Embryo = 2850 mg/L.; Mutation Test Systems - not otherwise
specified: Hamster, Fibroblast = 1 pph.; CAS# 64-17-5: DNA Inhibition: Human,
Lymphocyte = 220 mmol/L.; Cytogenetic Analysis: Human, Lymphocyte = 1160 gm/L.;
Sister Chromatid Exchange: Human, Lymphocyte = 500 ppm/72H (Continuous).
Other Studies: Open Irritation Test: Administration onto the skin (rabbit) = 360 mg
(Mild). Standard Draize Test: Administration into the eye (rabbit) = 100 mg (Moderate).
Standard Draize Test : Administration onto the skin (rabbit) = 50 mg/24H (Sev ere).
Standard Draize Test: Administration into the eye (human) = 100 ppm.
Section 12 - Ecological Information
Ecotoxicity: Fish: Fathead Minnow: LC50 = 2600 mg/L; 96 Hr; CAS# 60-29-7: Flowthrough bioassayFish: Bluegill/Sunfish: LC50 >10000 mg/L; 96 Hr; CAS# 60-29-7: Static
bioassayBacteria: Phytobacterium phosphoreum: EC50 = 5625 mg/L; 15 min; CAS# 6029-7: Microtox test CAS# 60-29-7: If ethyl ether is released to soil, it will be subject to
volatilization. It will be expected to exhibit high mobility in soil and, therefore, it may
leach to groundwater. If ethyl ether is released to water, it will not be expected to
significantly adsorb to sediment or suspended particulate matter, bioconcentrate in
aquatic organisms or hydrolyze.
Environmental: CAS# 60-29-7: Ethyl ether will not significantly photooxidize via
reaction with photochemically produced hydroxyl radicals in the water. Ethyl ether in
surface water will be subject to rapid volatilization with estimated half-lives of 3.1 hr and
1.5 days. It will not be expected to hydrolyze in water or soil. If ethyl ether is released to
the atmosphere, it will be expected to exist almost entirely in the vapor phase.It will be
susceptible to photooxidation via vapor phase reaction with photochemically produced
hydroxyl radicals with a half-life of 29 hours.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 60-29-7: waste number U117 (Ignitable waste).
Section 14 - Transport Information
US DOT
Shipping
Name:
NITROCELLULOSE,
SOLUTION,
FLAMMABLE
Hazard Class: 3
UN Number:
Packing
Group:
UN2059
II
IATA
RID/ADR
IMO
Canada TDG
No information
available.
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 60-29-7 is listed on the TSCA inventory.
CAS# 64-17-5 is listed on the TSCA inventory.
CAS# 9004-70-0 is listed on the TSCA inventory.
CAS# 8001-79-4 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 60-29-7: 100 lb final RQ; 45.4 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 60-29-7: acute, flammable, sudden release of pressure, reactive. CAS # 64-17-5:
acute, chronic, flammable. CAS # 9004-70-0: acute, flammable, reactive.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 60-29-7 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 64-17-5 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 9004-70-0 can be found on the following state right to know lists: New Jersey,
Pennsylvania, Massachusetts.
CAS# 8001-79-4 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
WARNING: This product contains Ethanol, a chemical known to the state of California to
cause birth defects or other reproductive harm. California No Significant Risk Level: None
of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XI F
Risk Phrases:
R 11 Highly flammable.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
S 9 Keep container in a well-ventilated place.
WGK (Water Danger/Protection)
CAS# 60-29-7: 1
CAS# 64-17-5: 0
CAS# 9004-70-0: 0
CAS# 8001-79-4: 1
Canada - DSL/NDSL
CAS# 60-29-7 is listed on Canada's DSL List.
CAS# 64-17-5 is listed on Canada's DSL List.
CAS# 9004-70-0 is listed on Canada's DSL List.
CAS# 8001-79-4 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2B.
Canadian Ingredient Disclosure List
CAS# 60-29-7 is listed on the Canadian Ingredient Disclosure List.
CAS# 64-17-5 is listed on the Canadian Ingredient Disclosure List.
CAS# 8001-79-4 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 60-29-7: OEL-AUSTRALIA:TWA 400 ppm (1200 mg/m3);STEL 500 ppm (1
500 mg/m3) OEL-AUSTRIA:TWA 400 ppm (1200 mg/m3) OEL-BELGIUM:TWA 400
ppm (1210 mg/m3);STEL 500 ppm (1520 mg/m3) OEL-CZECHOSLOVAKIA:TWA 500
mg/m3;STEL 1500 mg/m3 OEL-DENMARK:TWA 400 ppm (1200 mg/m3) OEL-FINL
AND:TWA 400 ppm (1200 mg/m3);STEL 500 ppm (1500 mg/m3) OEL-FRANCE:TWA
400 ppm (1200 mg/m3);STEL 500 ppm (1500 mg/m3) OEL-GERMANY:TWA 400 p
pm (1200 mg/m3) OEL-HUNGARY:TWA 300 mg/m3;STEL 600 mg/m3;Skin OEL-JA
PAN:TWA 400 ppm (1200 mg/m3) OEL-THE NETHERLANDS:TWA 400 ppm (1200 mg
/m3) JAN9 OEL-THE PHILIPPINES:TWA 400 ppm (1200 mg/m3) JAN9 OEL-POLA
ND:TWA 300 mg/m3 OEL-RUSSIA:TWA 400 ppm;STEL 300 mg/m3 OEL-SWEDEN:TW
A 400 ppm (1200 mg/m3);STEL 500 ppm (1500 mg/m3) OEL-SWITZERLAND:TWA
400 ppm (1200 mg/m3);STEL 800 ppm OEL-TURKEY:TWA 400 ppm (1200 mg/m3)
OEL-UNITED KINGDOM:TWA 400 ppm (1200 mg/m3);STEL 500 ppm OEL IN BUL
GARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SI
NGAPORE, VIETNAM check ACGI TLV
CAS# 64-17-5: OEL-AUSTRALIA:TWA 1000 ppm (1900 mg/m3) OEL-BELGIUM:T
WA 1000 ppm (1880 mg/m3) OEL-CZECHOSLOVAKIA:TWA 1000 mg/m3;STEL 5000
mg/m3 OEL-DENMARK:TWA 1000 ppm (1900 mg/m3) OEL-FINLAND:TWA 1000 ppm
(1900 mg/m3);STEL 1250 ppm (2400 mg/m3) OEL-FRANCE:TWA 1000 ppm (190
0 mg/m3);STEL 5000 pp OEL-GERMANY:TWA 1000 ppm (1900 mg/m3) OEL-HUNG
ARY:TWA 1000 mg/m3;STEL 3000 mg/m3 OEL-THE NETHERLANDS:TWA 1000 ppm (
1900 mg/m3) OEL-THE PHILIPPINES:TWA 1000 ppm (1900 mg/m3) OEL-POLAND
:TWA 1000 mg/m3 OEL-RUSSIA:STEL 1000 mg/m3 OEL-SWEDEN:TWA 1000 ppm (
1900 mg/m3) OEL-SWITZERLAND:TWA 1000 ppm (1900 mg/m3) OEL-THAILAND:T
WA 1000 ppm (1900 mg/m3) OEL-TURKEY:TWA 1000 ppm (1900 mg/m3) OEL-UN
ITED KINGDOM:TWA 1000 ppm (1900 mg/m3) JAN9 OEL IN BULGARIA, COLOMBIA
, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNA
M check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 6/02/1999
Revision #3 Date: 3/18/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Page 1 of 12
*********************************************************************
MATERIAL SAFETY DATA SHEET
HELENA LABORATORIES
1530 Lindbergh Dr./P.O. Box 752
Beaumont, TX 77704-0752
USA Toll Free 800-231-5663
*********************************************************************
DATE PREPARED:
REVISION:
1/24/1992
4
*********************************************************************
1.
IDENTIFICATION:
PRODUCT NAME:
COLOSCREEN DEVELOPER 15
PRODUCT NO.:
2.
5077
INGREDIENTS (THE ABOVE KIT CONTAINS THE FOLLOWING ITEMS):
PRODUCT NUMBER
PRODUCT IDENTIFICATION (LABEL NAME)
500091
COLOSCREEN DEVELOPER
HAZARDOUS INGREDIENT
*ETHANOL 190 PROOF
HYDROGEN PEROXIDE
SOLUTION
COMMENTS
CAS #
MIXTURE
%
70.0
MSDS ATTACHED
7722-84-1
13.0
MSDS ATTACHED
ATTACHED ARE THE MSDSs FOR THE ABOVE NAMED HAZARDOUS INGREDIENTS.
*THIS PRODUCT CONTAINS A TOXIC CHEMICAL THAT IS SUBJECT TO THE
REPORTING REQUIREMENTS OF SECTIONS 313 OF TITLE III OF THE SUPERFUND
AMENDMENTS AND REAUTHORIZATION ACT OF 1986 AND 40 CFR PART 372. THIS
CHEMICAL IS REFERENCED BY AN ASTERISK.
Page 2 of 12
*********************************************************************
MATERIAL SAFETY DATA SHEET
HELENA LABORATORIES
1530 Lindbergh Dr./P.O. Box 752
Beaumont, TX 77704-0752
USA Toll Free 800-231-5663
*********************************************************************
DATE PREPARED:
REVISION:
1/16/1992
4
*********************************************************************
1.
IDENTIFICATION:
NAME:
ETHANOL (190 PROOF)
CAS #: MIXTURE
CHEMICAL FAMILY:
MOLECULAR WEIGHT:
MOLECULAR FORMULA:
SYNONYMS:
2.
3.
ALCOHOL
46.07
C2H5OH
ETHYL ALCOHOL – 190 PROOF * ETHANOL *
HAZARDOUS INGREDIENTS:
CHEMICAL NAME/COMMON NAME
CAS #
%
EXPOSURE LIMITS
OSHA PEL
ACGIH TLV
ETHYL ALCOHOL
64-17-5
METHANOL
67-56-1
92.5
1000 PPM
7.5
200 PPM
1000 PPM
PHYSICAL DATA:
BOILING POINT:
173°F*
VAPOR PRESSURE (MM HG.):
44.6 MM HG AT 68°F*
VAPOR DENSITY (AIR = 1):
APPEARANCE AND ODOR:
SPECIFIC GRAVITY (H20 = 1):
AT 60/60°F*
MELTING POINT: -173°F*
1.59*
SOLUBILITY IN WATER:
0.8158
COMPLETE
CLEAR AND COLORLESS
NA = Not Applicable
NL = Not Listed
NE = Not Established
NIF = No Information Found
MSDS: ALCOHOL USP, ETHYL ALCOHOL, 190 PROOF
Page 3 of 12
*********************************************************************
4.
HEALTH HAZARD DATA:
PRIMARY ROUTE(S) OF ENTRY:
INHALATION?
YES
SKIN?
YES
CARCINOGENICITY:
IARC?
NO
NTP?
NO
INGESTION?
YES
ACUTE EFFECT OF OVEREXPOSURE:
EYES:
IRRITANT.
CONTINUED EXPOSURE MAY CAUSE LESIONS.
SKIN:
ALCOHOL IS A DEFATTING AGENT AND MAY CAUSE SKIN
TO BECOME DRY AND CRACKED. SKIN ABSORPTION CAN
OCCUR, SYMPTOMS MAY PARALLEL INHALATION EXPOSURE.
INHALATION:
A SLIGHT IRRITANT TO THE MUCOUS MEMBRANES. TOXIC
EFFECTS EXERTED UPON NERVOUS SYSTEM, PARTICULARLY
THE OPTIC NERVE. ONCE ABSORBED INTO THE BODY, IT
IS VERY SLOWLY ELIMINATED. SYMPTOMS OF
OVEREXPOSURE MAY INCLUDE HEADACHE, DROWSINESS,
NAUSEA, VOMITING, BLURRED VISION, BLINDNESS, COMA
AND DEATH. A PERSON MAY GET BETTER THEN WORSE
AGAIN UP TO 30 HOURS LATER. CHRONIC EFFECTS OF
EXPOSURE:
INGESTION:
TOXIC. SYMPTOMS PARALLEL INHALATION.
INTOXICATE AND CAUSE BLINDNESS.
CAN
CHRONIC EFFECTS OF EXPOSURE:
SWALLOWING:
IF VICTIM IS CONSCIOUS AND ABLE TO SWALLOW, HAVE
VICTIM DRINK WATER OR MILK TO DILUTE. NEVER GIVE
ANYTHING BY MOUTH IF VICTIM IS UNCONSCIOUS OR
HAVING CONVULSIONS. CALL A PHYSICIAN OR CONTROL
CENTER IMMEDIATELY. INDUCE VOMITING ONLY IF
ADVISED BY PHYSICIAN OR POISON CONTROL CENTER.
INHALATION:
IMMEDIATELY REMOVE VICTIM TO FRESH AIR. IF
VICTIM HAS STOPPED BREATHING, GIVE ARTIFICIAL
RESPIRATION, PREFERABLY MOUTH-TO-MOUTH. GET
MEDICAL ATTENTION IMMEDIATELY.
CONTACT WITH EYES OR SKIN: IMMEDIATELY FLUSH AFFECTED AREA WITH
PLENTY OF COOL WATER. EYES SHOULD BE FLUSHED FOR
AT LEAST 15 MINUTES. REMOVE AND WASH
CONTAMINATED CLOTHING BEFORE REUSE. GET MEDICAL
ATTENTION IMMEDIATELY.
MSDS: ALCOHOL USP, ETHYL ALCOHOL, 190 PROOF
Page 4 of 12
*********************************************************************
4.
HEALTH HAZARD DATA (CONT):
TOXICITY DATA: ORAL RAT LD50:5628 MG/KG. SKIN RABBIT: 20 GM/KG.
AQUATIC TOXICITY RATING TLM 96: OVER 1,000. MUTATION DATA CITED.
REPRODUCTIVE EFFECTS DATA CITED.
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: PERSONS WITH PRE-EXISTING
SKIN DISORDERS OR EYE PROBLEMS OR IMPAIRED LIVER OR KIDNEY FUNCTION
MAY BE MORE SUSCEPTIBLE TO THE EFFECTS OF THE SUBSTANCE.
EMERGENCY AND FIRST AID PROCEDURES:
5.
EYE CONTACT:
WASH EYES WITH PLENTY OF WATER FOR AT LEAST 15
MINUTES, LIFTING LOWER AND UPPER EYELIDS
OCCASIONALLY. GET MEDICAL ATTENTION IMMEDIATELY.
SKIN CONTACT:
REMOVE ANY CONTAMINATED CLOTHING. WASH SKIN WITH
SOAP OR MILD DETERGENT AND WATER FOR AT LEAST 15
MINUTES. GET MEDICAL ATTENTION IF IRRITATION
DEVELOPS OR PERSISTS.
INHALATION:
REMOVE TO FRESH AIR. IF NOT BREATHING, GIVE
ARTIFICIAL RESPIRATION. IF BREATHING IS
DIFFICULT, GIVE OXYGEN. CALL A PHYSICIAN.
INGESTION:
IF SWALLOWED, INDUCE VOMITING IMMEDIATELY BY
GIVING TWO GLASSES OF WATER AND STICKING FINGER
DOWN THROAT. NEVER GIVE ANYTHING BY MOUTH TO AN
UNCONSCIOUS PERSON. CALL PHYSICIAN IMMEDIATELY.
FIRE AND EXPLOSION HAZARD DATA:
FLASH POINT (METHOD USED):
FLAMMABLE LIMITS:
EXTINGUISHING MEDIA:
60°F ASTM D-56 (TAG CLOSED CUP)
LEL
3.3*
UEL
19*
DRY CHEMICAL, “ALCOHOL” FOAM, OR CARBON DIOXIDE
SPECIAL FIRE FIGHTING PROCEDURES: (NOTE: INDIVIDUALS SHOULD PERFORM
ONLY THOSE FIRE-FIGHTING PROCEDURES FOR WHICH THEY HAVE BEEN
TRAINED.) USE DRY CHEMICAL, “ALCOHOL” FOAM, OR CARBON DIOXIDE; WATER
MAY BE INEFFECTIVE, BUT WATER SHOULD BE USED TO KEEP FIRE-EXPOSED
CONTAINERS COOL. IF A LEAK OR SPILL HAS NOT IGNITED, USE WATER SPRAY
TO DISPERSE THE VAPORS AND TO PROTECT MEN ATTEMPTING TO STOP A LEAK.
WATER SPRAY MAY BE USED TO FLUSH SPILLS AWAY FROM EXPOSURES AND TO
DILUTE SPILLS TO NONFLAMMABLE MIXTURES (NFPA-49 1975).
UNUSUAL FIRE AND EXPLOSION HAZARDS: FIRE FIGHTERS SHOULD WEAR SELFCONTAINED BREATHING APPARATUS IN THE POSITIVE PRESSURE MODE WITH A
FULL FACEPIECE WHEN THERE IS A POSSIBILITY OF EXPOSURE TO SMOKE,
FUMES OR HAZARDOUS DECOMPOSITION PRODUCTS.
MSDS: ALCOHOL USP, ETHYL ALCOHOL, 190 PROOF
Page 5 of 12
*********************************************************************
6.
REACTIVITY DATA:
STABILITY:
UNSTABLE:
STABLE:
X
INCOMPATIBILITY (MATERIALS TO AVOID): CONTACT WITH ACETYL CHLORIDE
AND A WIDE RANGE OF OXIDIZING AGENTS MAY REACT VIOLENTLY.
* FOR PURE ETHYL ALCOHOL
HAZARDOUS DECOMPOSITION OF BY-PRODUCTS: CARBON OXIDES AND
FORMALDEHYDE MAY FORM WHEN HEATED TO DECOMPOSITION.
HAZARDOUS POLYMERIZATION:
MAY OCCUR:
7.
WILL NOT OCCUR:
X
SPILL OR LEAK PROCEDURES:
STEPS TO BE TAKEN IN CASE MATERIAL IS RELEASED OR SPILLED: AVOID
UNCONTROLLED RELEASES OF THIS MATERIAL. WHERE SPILLS ARE POSSIBLE, A
COMPREHENSIVE SPILL RESPONSE PLAN SHOULD BE DEVELOPED AND
IMPLEMENTED. WEAR APPROPRIATE RESPIRATORY PROTECTION AND PROTECTIVE
CLOTHING AS DESCRIBED IN SPECIAL PROTECTION INFORMATION. CONTAIN
SPILLED MATERIAL. TRANSFER TO SECURE CONTAINERS. WHERE NECESSARY,
COLLECT USING ABSORBENT MEDIA. IN THE EVENT OF AN UNCONTROLLED
RELEASE OF THIS MATERIAL, THE USER SHOULD DETERMINE IF THE RELEASE IS
REPORTABLE UNDER APPLICABLE LAWS AND REGULATIONS.
WASTE DISPOSAL METHODS:
8.
OBSERVE ALL FEDERAL AND STATE REGULATIONS
SPECIAL PROTECTION INFORMATION:
RESPIRATORY PROTECTION (SPECIFY TYPE): WHERE EXPOSURE IS LIKELY TO
EXCEED ACCEPTABLE CRITERIA, USE NIOSH/MSHA APPROVED RESPIRATORY
PROTECTION EQUIPMENT. RESPIRATORS SHOULD BE SELECTED BASED ON THE
FORM AND CONCENTRATION OF CONTAMINANT IN AIR AND IN ACCORDANCE WITH
OSHA (29 CFR 1910.134).
VENTILATION:
LOCAL EXHAUST:
OTHER:
X
MECHANICAL:
PROTECTIVE GLOVES: WEAR GLOVES WHICH ARE IMPERVIOUS TO THE PRODUCT
FOR THE DURATION OF THE ANTICIPATED EXPOSURE IF THERE IS POTENTIAL
FOR PROLONGED OR REPEATED SKIN CONTACT.
EYE PROTECTION:
WEAR SAFETY GLASSES MEETING THE SPECIFICATIONS OF
ANSI STANDARD Z87.1 WHERE NO CONTACT WITH THE EYE IS ANTICIPATED.
CHEMICAL SAFETY GOGGLES MEETING THE SPECIFICATIONS OF ANSI STANDARD
Z87.1 SHOULD BE WORN WHENEVER THERE IS THE POSSIBILITY OF SPLASHING
OR OTHER CONTACT WITH THE EYES.
MSDS: ALCOHOL USP, ETHYL ALCOHOL, 190 PROOF
Page 6 of 12
*********************************************************************
8.
SPECIAL PROTECTION INFORMATION (CONT):
OTHER PROTECTIVE EQUIPMENT: PROTECTIVE CLOTHING WHICH IS IMPERVIOUS
TO THE PRODUCT FOR THE DURATION OF THE ANTICIPATED EXPOSURE IF THERE
IS POTENTIAL FOR PROLONGED OR REPEATED SKIN CONTACT.
9.
SPECIAL PRECAUTIONS:
PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE: PROTECT CONTAINER
AGAINST PHYSICAL DAMAGE. DETACHED OR OUTSIDE STORAGE IS PREFERRED.
INSIDE STORAGE SHOULD BE IN AN NFPA APPROVED FLAMMABLE LIQUID STORAGE
ROOM OR CABINET. ALL IGNITION SHOULD BE ELIMINATED. SMOKING SHOULD
BE PROHIBITED IN STORAGE AREAS. ELECTRICAL INSTALLATIONS SHOULD BE
IN ACCORDANCE WITH ARTICLE 501 OF THE NATIONAL ELECTRICAL CODE. NFPA
30, FLAMMABLE AND COMBUSTIBLE LIQUIDS CODE, SHOULD BE FOLLOWED FOR
ALL STORAGE AND HANDLING. FREQUENT CAREFUL LEAKAGE INSPECTIONS
SHOULD BE DONE. AUTOMATIC SPRINKLER SYSTEM SHOULD BE PROVIDED.
ISOLATE FROM OXIDIZERS, CHEMICALS CAPABLE OF SPONTANEOUS HEATING,
MATERIALS REACTING WITH AIR OR MOISTURE TO LIBERATE HEAT, IGNITION
SOURCES AND EXPLOSIVES. CONSULT LOCAL FIRE CODES FOR ADDITIONAL
STORAGE INFORMATION.
WHEN CONTENTS ARE BEING TRANSFERRED, THE METALLIC CONTAINER MUST BE
BONDED TO THE RECEIVING CONTAINER AND GROUNDED TO AVOID STATIC
DISCHARGES. NEVER USE PRESSURE TO EMPTY. REPLACE CLOSURE SECURELY
AFTER EACH OPENING.
KEEP MATERIAL PACKAGED IN DRUMS OR BOTTLES OUT OF SUN AND AWAY FROM
HEAT. REMOVE CLOSURE CAREFULLY; INTERNAL PRESSURE MAY BE PRESENT.
KEEP CLOSURE UP TO PREVENT LEAKAGE.
CONTAINER HAZARDOUS WHEN EMPTY. SINCE EMPTIED CONTAINERS RETAIN
RESIDUAL PRODUCT (VAPOR AND LIQUID), ALL PRECAUTIONS DESCRIBED ON
THIS MSDS MUST BE OBSERVED.
CAUTION: FOR MANUFACTURING, PROCESSING, REPACKING OR INDUSTRIAL USE.
NOT FOR HOUSEHOLD USE.
OTHER PRECAUTIONS:
10.
OTHER INFORMATION:
*********************************************************************
The information herein is given in good faith but no warranty,
expressed or implied, is made.
Page 7 of 12
*********************************************************************
MATERIAL SAFETY DATA SHEET
HELENA LABORATORIES
1530 Lindbergh Dr./P.O. Box 752
Beaumont, TX 77704-0752
USA Toll Free 800-231-5663
*********************************************************************
DATE PREPARED: 1/16/1992
REVISION:
3
*********************************************************************
1.
IDENTIFICATION:
PRODUCT NAME:
HYDROGEN PEROXIDE SOLUTIONS
CAS #.:
CHEMICAL FAMILY:
MOLECULAR FORMULA:
MOLECULAR WEIGHT:
7722-84-1
PEROXIDE
H2-02
34.02
SYNONYMS: HYDROGEN PEROXIDE SOLUTION, 30-50% * STCC 4918776 * UN
2014 * H-323 * H-325 * H-327 * H-341 * ACC11189 *
2.
HAZARDOUS INGREDIENTS:
CHEMICAL NAME/COMMON NAME
CAS #
HYDROGEN PEROXIDE
3.
%
EXPOSURE LIMITS
OSHA PEL
ACGIH TLV
30-50%
1 PPM
(1.4 MG/M3)
1 PPM
(1.4 MG/M3)
PHYSICAL DATA:
BOILING POINT:
223°F (106°C)
VAPOR PRESSURE (MM HG.):
25 AT 30°C
VAPOR DENSITY (AIR = 1):
SPECIFIC GRAVITY (H20 = 1):
MELTING POINT:
1.2
1.1
-13°F (-25°C)
SOLUBILITY IN WATER:
SOLUBLE
APPEARANCE AND ODOR: COLORLESS, CLEAR WATER-LIKE LIQUID/SLIGHTLY
SHARP ODOR AND BITTER TASTE
NA = Not Applicable
NL = Not Listed
NE = Not Established
NIF = No Information Found
MSDS: HYDROGEN PEROXIDE SOLUTION
Page 8 of 12
*********************************************************************
4.
HEALTH HAZARD DATA:
PRIMARY ROUTE(S) OF ENTRY:
INHALATION? YES
CARCINOGENICITY:
NTP?
NO
SKIN?
YES
IARC?
NO
INGESTION?
YES
ACUTE EFFECT OF OVEREXPOSURE:
EYES:
CORROSIVE. VAPORS MAY CAUSE IRRITATION, REDNESS,
PAIN AND BLURRED VISION. DIRECT CONTACT WITH
LIQUID MAY CAUSE CORNEAL BURNS AND POSSIBLE
BLINDNESS.
SKIN:
CORROSIVE. MAY CAUSE IRRITATION, PAIN, BLEACHING
OF THE SKIN AND HAIR, AND ON PROLONGED CONTACT WITH
LIQUID, BURNS.
INHALATION:
CORROSIVE. 75 PPM IS IMMEDIATELY DANGEROUS TO LIFE
AND HEALTH. MAY CAUSE IRRITATION AND INFLAMMATION
OF RESPIRATORY TRACT, SORE THROAT, COUGHING,
DYSPNEA, LABORED BREATHING AND DELAYED PULMONARY
EDEMA.
INGESTION:
CORROSIVE/LIMITED ANIMAL CARCINOGEN. MAY CAUSE
SORE THROAT, FOCAL AND DIFFUSE BURNS OF THE
ESOPHAGUS, ABDOMINAL PAIN, CHEST PAIN, VOMITING,
DIARRHEA AND DISTENTION AND DAMAGE OF THE
ESOPHAGUS, STOMACH OR ABDOMEN DUE TO RELEASE OF
OXYGEN.
CHRONIC EFFECTS OF EXPOSURE:
EYE:
MAY CAUSE CONJUNCTIVITIS AND LACRIMATION.
SKIN:
REPEATED OR PROLONGED EXPOSURE MAY CAUSE BLEACHING
OF THE HAIR, DERMATITIS, IN SOME INDIVIDUALS,
ECZEMA.
INHALATION:
REPEATED OR PROLONGED EXPOSURE MAY CAUSE SNEEZING,
LACRIMATION AND BLEACHING OF HAIR.
INGESTION:
ORAL ADMINISTRATION IN MICE HAS RESULTED IN
ADENOMAS AND CARCINOMAS OF THE DUODENUM.
TOXICITY DATA:
ORL-MAN LDLO 1429 MG/KG
MSDS: HYDROGEN PEROXIDE SOLUTION
Page 9 of 12
*********************************************************************
4.
HEALTH HAZARD DATA (CONT)
EMERGENCY AND FIRST AID PROCEDURES:
5.
EYE CONTACT:
WASH EYES IMMEDIATELY WITH LARGE AMOUNTS OF
WATER, FOR AT LEAST 15-20 MINUTES, OCCASIONALLY
LIFTING UPPER AND LOWER LIDS, UNTIL NO EVIDENCES
OF CHEMICAL REMAINS. CONTINUE IRRIGATING WITH
NORMAL SALINE UNTIL THE pH HAS RETURNED TO NORMAL
(30-60 MINUTES). COVER WITH STERILE BANDAGES.
GET MEDICAL ATTENTION IMMEDIATELY.
SKIN CONTACT:
REMOVE CONTAMINATED CLOTHING AND SHOES
IMMEDIATELY. WASH AFFECTED AREA WITH SOAP OR
MILD DETERGENT AND LARGE AMOUNTS OF WATER UNTIL
NO EVIDENCE OF CHEMICAL REMAINS (AT LEAST 15-20
MINUTES). IN CASE OF CHEMICAL BURNS, COVER AREA
WITH STERILE, DRY DRESSING, BANDAGE SECURELY, BUT
NOT TOO TIGHTLY. GET MEDICAL ATTENTION
IMMEDIATELY.
INHALATION:
REMOVE FROM EXPOSURE AREA TO FRESH AIR
IMMEDIATELY. IF BREATHING HAS STOPPED, GIVE
ARTIFICIAL RESPIRATION. MAINTAIN AIRWAY AND
BLOOD PRESSURE AND ADMINISTER OXYGEN IF
AVAILABLE. KEEP AFFECTED PERSON WARM AND AT
REST. TREAT SYMPTOMATICALLY AND SUPPORTIVELY.
ADMINISTRATION OF OXYGEN SHOULD BE PERFORMED BY
QUALIFIED PERSONNEL. GET MEDICAL ATTENTION
IMMEDIATELY.
INGESTION:
IF THE PERSON IS CONSCIOUS AND NOT CONVULSING,
GIVE 2-4 GLASSES OF WATER TO DILUTE THE CHEMICAL.
USE GASTRIC TUBE TO RELIEVE THE PRESSURE CAUSED
BY EVOLVED OXYGEN (DREISBACH, HANDBOOK OF
POISONING 12TH EDITION). TREAT SYMPTOMATICALLY
AND SUPPORTIVELY. INTUBATION SHOULD BE PERFORMED
BY QUALIFIED MEDICAL PERSONNEL. GET MEDICAL
ATTENTION IMMEDIATELY.
FIRE AND EXPLOSION HAZARD DATA:
FLASH POINT (METHOD USED):
FLAMMABLE LIMITS:
NON-COMBUSTIBLE
LEL
NA
UEL
NA
EXTINGUISHING MEDIA: WATER ONLY, NO DRY CHEMICAL, CARBON DIOXIDE OR
HALON. FOR LARGER FIRES, FLOOD AREA WITH WATER FROM A DISTANCE.
SPECIAL FIRE FIGHTING PROCEDURES: MOVE CONTAINER FROM FIRE AREA IF
POSSIBLE WITHOUT RISK. APPLY COOLING WATER TO SIDES OF CONTAINERS
THAT ARE EXPOSED TO FLAMES UNTIL WELL AFTER FIRE IS OUT. STAY AWAY
MSDS: HYDROGEN PEROXIDE SOLUTION
Page 10 of 12
*********************************************************************
5. FIRE AND EXPLOSION HAZARD DATA (CONT):
FROM ENDS OF TANKS. FOR MASSIVE FIRE IN CARGO AREA, USE UNMANNED
HOSE HOLDER OR MONITOR NOZZLES; IF THIS IS IMPOSSIBLE, WITHDRAW FROM
AREA AND LET FIRE BURN. USE WATER IN FLOODING AMOUNTS AS A FOG.
COOL CONTAINERS WITH FLOODING QUANTITIES OF WATER, APPLY FROM AS FAR
A DISTANCE AS POSSIBLE. AVOID BREATHING TOXIC VAPORS, KEEP UPWIND.
UNUSUAL
EXPOSED
HEATED,
BURNING
ORGANIC
VIOLENT
6.
FIRE AND EXPLOSION HAZARDS: NEGLIGIBLE FIRE HAZARD WHEN
TO HEAT OR FLAME. OXIDIZERS DECOMPOSE, ESPECIALLY WHEN
TO YIELD OXYGEN OR OTHER GASES WHICH WILL INCREASE THE
RATE OF COMBUSTIBLE MATTER. CONTACT WITH EASILY OXIDIZABLE,
OR OTHER COMBUSTIBLE MATERIALS MAY RESULT IN IGNITION,
COMBUSTION OR EXPLOSION.
REACTIVITY DATA:
STABILITY:
UNSTABLE:
STABLE:
X
INCOMPATIBILITY (MATERIALS TO AVOID):
EXPLOSION
EXPLOSIVE IGNITION
POSSIBLE EXPLOSION
VIOLENT REACTION
VIOLENT DECOMPOSITION
DECOMPOSITION
POSSIBLE DECOMPOSITION
IGNITION AND POSSIBLE
EXPLOSION
- ACETONE, DIMETHYL BENZYLCARBINOL AND
SULFURIC ACID, 2-METHYL-1-PHENYL-2PROPANOL AND SULFURIC ACID, PLATINUM,
KETONES AND NITRIC ACID, ORGANIC
MATTER, THIODIGLYCOL AND ACETONE ON
HEATING, GLYCERIN, ACETIC ACID AND NHETEROCYCLES, CHLOROSULFONIC ACID,
FORMIC ACID AND METABORIC ACID,
SULFURIC ACID ON EVAPORATION, VINYL
ACETATE AND OSMIUM TETRAOXIDE.
- LITHIUM TETRAHYDROALUMINATE.
- ACETAL AND ACETIC ACID, N-BUTANOL AND
SULFURIC ACID, FORMIC ACID AND ORGANIC
SUBSTANCES, SILVER, POWDERED MANGANESE
DIOXIDE, FERRIC SULFATE AND 2METHYLPYRIDINE AND SULFURIC ACID,
TETRAHYDROTHIOPHENE.
- DIPHOSPHOROUS PENTOXIDE, POTASSIUM
PERMANGANATE, LEAD DIOXIDE, LEAD
MONOXIDE, POTASSIUM, SODIUM,
PHOSPHORUS(V) OXIDE.
- BRASS, BRONZE, CARBON, CHROMIUM,
COPPER, IRON, LEAD, MERCURIC OXIDE,
MERCUROUS OXIDE, MAGNESIUM, MANGANESE,
MANGANESE DIOXIDE, SILVER,
BENZENSULPHONIC ANHYDRIDE.
- HYDROGEN SESENIDE, SODIUM IODATE.
- NITROGENOUS BASES.
- ACETIC ACID ON HEATING.
MSDS: HYDROGEN PEROXIDE SOLUTION
Page 11 of 12
*********************************************************************
6.
REACTIVITY DATA (CONT):
IGNITION
RED LUMINESCENCE
POSSIBLE IGNITION
INTENSE EXOTHERMIC
REACTION
VIGOROUS REACTION
FORMATION OF EXPLOSIVE
COMPOUND
FORMATION OF POSSIBLE
EXPLOSIVE COMPOUND.
- UNSYM-DIMETHYL HYDRAZINE, FURFURYL
ALCOHOL, HYDRAZINE AND NITRIC ACID,
MANGANESE, SILVER, CELLULOSE,
CHARCOAL, ALUMINUM ISOPROPOXIDE AND
HEAVY METAL SALTS, WOOD.
- CHLORINE AND POTASSIUM HYDROXIDE.
- PHOSPHORUS
- STAMMOUS CHLORIDE, APHENYLSELENOKETONES.
- ANTIMONY TRISULFIDE, ARSENIC
TRISULFIDE, CUPRIC SULFIDE, LEAD
SULFIDE, MOLYBDENUM DISULFIDE, FERROUS
SULFIDE.
- ALCOHOLS, ESPECIALLY ETHYL,
ACETALDEHYDE AND DESICCANTS, KETONES
AND NITRIC ACID, NITRIC ACID AND
THIOUREA, GADOLINIUM HYDROXIDE, 2METHYL-2-PROPENYL TETRAHYDROPYRANYL
ETHER AND SODIUM SULPHITE, KETENE,
LEAD AND TRIOXANED.
- NITRIC ACID (> 50%)
HAZARDOUS DECOMPOSITION OF BY-PRODUCTS: THERMAL DECOMPOSITION
RELEASES FLAMMABLE OXYGEN AND HEAT. REACTION BECOMES SELF-SUSTAINING
AT 141°C. DECOMPOSITION IS ACCELERATED BY AGITATION, CONTACT WITH
ROUGH SURFACES, ALKALIS, FINELY DIVIDED METALS, AND MANY OTHER
SUBSTANCES.
HAZARDOUS POLYMERIZATION:
MAY OCCUR:
7.
WILL NOT OCCUR:
X
SPILL OR LEAK PROCEDURES:
STEPS TO BE TAKEN IN CASE MATERIAL IS RELEASED OR SPILLED: KEEP
COMBUSTIBLES (WOOD, PAPER, OIL, ETC.) AWAY FROM SPILLED MATERIAL, DO
NOT TOUCH MATERIAL. STOP LEAK IF POSSIBLE WITHOUT RISK. USE WATER
SPRAY TO REDUCE VAPORS. DO NOT GET WATER INSIDE CONTAINER. FOR
SMALL DRY SPILLS, WITH CLEAN SHOVEL PLACE MATERIAL INTO CLEAN, DRY
CONTAINER AND COVER. MOVE CONTAINERS FROM SPILL AREA. FOR SMALL
LIQUID SPILLS, FLUSH AREA WITH FLOODING AMOUNTS OF WATER. FOR LARGER
SPILLS, DIKE FAR AHEAD OF SPILL FOR LATER DISPOSAL. KEEP UNNECESSARY
PEOPLE AWAY. ISOLATE HAZARD AREA AND DENY ENTRY.
THE SUPERFUND AMENDMENTS AND REAUTHORIZATION ACT (SARA) SECTION 304
REQUIRES THAT A RELEASE GREATER THAN THE REPORTABLE QUANTITY (1
POUND) FOR THIS SUBSTANCE BE IMMEDIATELY REPORTED TO THE LOCAL
EMERGENCY PLANNING COMMITTEE AND THE STATE EMERGENCY RESPONSE
MSDS: HYDROGEN PEROXIDE SOLUTION
Page 12 of 12
*********************************************************************
7.
SPILL OR LEAK PROCEDURES (CONT)
COMMISSION (40 CFR 355.40). IF THE RELEASE OF THIS SUBSTANCE IS
REPORTABLE UNDER CERCLA SECTION 103, THE NATIONAL RESPONSE CENTER
MUST BE NOTIFIED IMMEDIATELY (40 CFR 302.6).
WASTE DISPOSAL METHODS:
REGULATIONS.
8.
OBSERVE ALL FEDERAL, STATE AND LOCAL
SPECIAL PROTECTION INFORMATION:
RESPIRATORY PROTECTION (SPECIFY TYPE): THE SPECIFIC RESPIRATOR
SELECTED MUST BE BASED ON CONTAMINATION LEVELS FOUND IN THE WORK
PLACE, MUST NOT EXCEED THE WORKING LIMITS OF THE RESPIRATOR AND BE
JOINTLY APPROVED BY NIOSH/MSHA.
VENTILATION:
LOCAL EXHAUST:
OTHER:
X
MECHANICAL:
PROTECTIVE GLOVES:
APPROPRIATE PROTECTIVE GLOVES TO PREVENT CONTACT.
EYE PROTECTION:
SPLASH-PROOF OR DUST-RESISTANT SAFETY GOGGLES.
OTHER PROTECTIVE EQUIPMENT: IMPERVIOUS CLOTHING TO PREVENT REPEATED
OR PROLONGED SKIN CONTACT. EYE BATH.
9.
SPECIAL PRECAUTIONS:
PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE:
INCOMPATIBLE SUBSTANCES.
OTHER PRECAUTIONS:
10.
STORE AWAY FROM
NA
OTHER INFORMATION:
NA
*********************************************************************
The information herein is given in good faith but no warranty,
expressed or implied, is made.
Page 1 of 12
*********************************************************************
MATERIAL SAFETY DATA SHEET
HELENA LABORATORIES
1530 Lindbergh Dr./P.O. Box 752
Beaumont, TX 77704-0752
USA Toll Free 800-231-5663
*********************************************************************
DATE PREPARED:
REVISION:
1/24/1992
3
*********************************************************************
1.
IDENTIFICATION:
PRODUCT NAME:
COLOSCREEN DEVELOPER 2
PRODUCT NO.:
2.
5078
INGREDIENTS (THE ABOVE KIT CONTAINS THE FOLLOWING ITEMS):
PRODUCT NUMBER
PRODUCT IDENTIFICATION (LABEL NAME)
500606
COLOSCREEN DEVELOPER
HAZARDOUS INGREDIENT
*ETHANOL 190 PROOF
HYDROGEN PEROXIDE
SOLUTION
COMMENTS
CAS #
MIXTURE
%
70.0
MSDS ATTACHED
7722-84-1
13.0
MSDS ATTACHED
ATTACHED ARE THE MSDSs FOR THE ABOVE NAMED HAZARDOUS INGREDIENTS.
*THIS PRODUCT CONTAINS A TOXIC CHEMICAL THAT IS SUBJECT TO THE
REPORTING REQUIREMENTS OF SECTIONS 313 OF TITLE III OF THE SUPERFUND
AMENDMENTS AND REAUTHORIZATION ACT OF 1986 AND 40 CFR PART 372. THIS
CHEMICAL IS REFERENCED BY AN ASTERISK.
Page 2 of 12
*********************************************************************
MATERIAL SAFETY DATA SHEET
HELENA LABORATORIES
1530 Lindbergh Dr./P.O. Box 752
Beaumont, TX 77704-0752
USA Toll Free 800-231-5663
*********************************************************************
DATE PREPARED:
REVISION:
1/16/1992
4
*********************************************************************
1.
IDENTIFICATION:
NAME:
ETHANOL (190 PROOF)
CAS #: MIXTURE
CHEMICAL FAMILY:
MOLECULAR WEIGHT:
MOLECULAR FORMULA:
SYNONYMS:
2.
3.
ALCOHOL
46.07
C2H5OH
ETHYL ALCOHOL – 190 PROOF * ETHANOL *
HAZARDOUS INGREDIENTS:
CHEMICAL NAME/COMMON NAME
CAS #
%
EXPOSURE LIMITS
OSHA PEL
ACGIH TLV
ETHYL ALCOHOL
64-17-5
METHANOL
67-56-1
92.5
1000 PPM
7.5
200 PPM
1000 PPM
PHYSICAL DATA:
BOILING POINT:
173°F*
VAPOR PRESSURE (MM HG.):
44.6 MM HG AT 68°F*
VAPOR DENSITY (AIR = 1):
APPEARANCE AND ODOR:
SPECIFIC GRAVITY (H20 = 1):
AT 60/60°F*
MELTING POINT: -173°F*
1.59*
SOLUBILITY IN WATER:
0.8158
COMPLETE
CLEAR AND COLORLESS
NA = Not Applicable
NL = Not Listed
NE = Not Established
NIF = No Information Found
MSDS: ALCOHOL USP, ETHYL ALCOHOL, 190 PROOF
Page 3 of 12
*********************************************************************
4.
HEALTH HAZARD DATA:
PRIMARY ROUTE(S) OF ENTRY:
INHALATION?
YES
SKIN?
YES
CARCINOGENICITY:
IARC?
NO
NTP?
NO
INGESTION?
YES
ACUTE EFFECT OF OVEREXPOSURE:
EYES:
IRRITANT.
CONTINUED EXPOSURE MAY CAUSE LESIONS.
SKIN:
ALCOHOL IS A DEFATTING AGENT AND MAY CAUSE SKIN
TO BECOME DRY AND CRACKED. SKIN ABSORPTION CAN
OCCUR, SYMPTOMS MAY PARALLEL INHALATION EXPOSURE.
INHALATION:
A SLIGHT IRRITANT TO THE MUCOUS MEMBRANES. TOXIC
EFFECTS EXERTED UPON NERVOUS SYSTEM, PARTICULARLY
THE OPTIC NERVE. ONCE ABSORBED INTO THE BODY, IT
IS VERY SLOWLY ELIMINATED. SYMPTOMS OF
OVEREXPOSURE MAY INCLUDE HEADACHE, DROWSINESS,
NAUSEA, VOMITING, BLURRED VISION, BLINDNESS, COMA
AND DEATH. A PERSON MAY GET BETTER THEN WORSE
AGAIN UP TO 30 HOURS LATER. CHRONIC EFFECTS OF
EXPOSURE:
INGESTION:
TOXIC. SYMPTOMS PARALLEL INHALATION.
INTOXICATE AND CAUSE BLINDNESS.
CAN
CHRONIC EFFECTS OF EXPOSURE:
SWALLOWING:
IF VICTIM IS CONSCIOUS AND ABLE TO SWALLOW, HAVE
VICTIM DRINK WATER OR MILK TO DILUTE. NEVER GIVE
ANYTHING BY MOUTH IF VICTIM IS UNCONSCIOUS OR
HAVING CONVULSIONS. CALL A PHYSICIAN OR CONTROL
CENTER IMMEDIATELY. INDUCE VOMITING ONLY IF
ADVISED BY PHYSICIAN OR POISON CONTROL CENTER.
INHALATION:
IMMEDIATELY REMOVE VICTIM TO FRESH AIR. IF
VICTIM HAS STOPPED BREATHING, GIVE ARTIFICIAL
RESPIRATION, PREFERABLY MOUTH-TO-MOUTH. GET
MEDICAL ATTENTION IMMEDIATELY.
CONTACT WITH EYES OR SKIN: IMMEDIATELY FLUSH AFFECTED AREA WITH
PLENTY OF COOL WATER. EYES SHOULD BE FLUSHED FOR
AT LEAST 15 MINUTES. REMOVE AND WASH
CONTAMINATED CLOTHING BEFORE REUSE. GET MEDICAL
ATTENTION IMMEDIATELY.
MSDS: ALCOHOL USP, ETHYL ALCOHOL, 190 PROOF
Page 4 of 12
*********************************************************************
4.
HEALTH HAZARD DATA (CONT):
TOXICITY DATA: ORAL RAT LD50:5628 MG/KG. SKIN RABBIT: 20 GM/KG.
AQUATIC TOXICITY RATING TLM 96: OVER 1,000. MUTATION DATA CITED.
REPRODUCTIVE EFFECTS DATA CITED.
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: PERSONS WITH PRE-EXISTING
SKIN DISORDERS OR EYE PROBLEMS OR IMPAIRED LIVER OR KIDNEY FUNCTION
MAY BE MORE SUSCEPTIBLE TO THE EFFECTS OF THE SUBSTANCE.
EMERGENCY AND FIRST AID PROCEDURES:
5.
EYE CONTACT:
WASH EYES WITH PLENTY OF WATER FOR AT LEAST 15
MINUTES, LIFTING LOWER AND UPPER EYELIDS
OCCASIONALLY. GET MEDICAL ATTENTION IMMEDIATELY.
SKIN CONTACT:
REMOVE ANY CONTAMINATED CLOTHING. WASH SKIN WITH
SOAP OR MILD DETERGENT AND WATER FOR AT LEAST 15
MINUTES. GET MEDICAL ATTENTION IF IRRITATION
DEVELOPS OR PERSISTS.
INHALATION:
REMOVE TO FRESH AIR. IF NOT BREATHING, GIVE
ARTIFICIAL RESPIRATION. IF BREATHING IS
DIFFICULT, GIVE OXYGEN. CALL A PHYSICIAN.
INGESTION:
IF SWALLOWED, INDUCE VOMITING IMMEDIATELY BY
GIVING TWO GLASSES OF WATER AND STICKING FINGER
DOWN THROAT. NEVER GIVE ANYTHING BY MOUTH TO AN
UNCONSCIOUS PERSON. CALL PHYSICIAN IMMEDIATELY.
FIRE AND EXPLOSION HAZARD DATA:
FLASH POINT (METHOD USED):
FLAMMABLE LIMITS:
EXTINGUISHING MEDIA:
60°F ASTM D-56 (TAG CLOSED CUP)
LEL
3.3*
UEL
19*
DRY CHEMICAL, “ALCOHOL” FOAM, OR CARBON DIOXIDE
SPECIAL FIRE FIGHTING PROCEDURES: (NOTE: INDIVIDUALS SHOULD PERFORM
ONLY THOSE FIRE-FIGHTING PROCEDURES FOR WHICH THEY HAVE BEEN
TRAINED.) USE DRY CHEMICAL, “ALCOHOL” FOAM, OR CARBON DIOXIDE; WATER
MAY BE INEFFECTIVE, BUT WATER SHOULD BE USED TO KEEP FIRE-EXPOSED
CONTAINERS COOL. IF A LEAK OR SPILL HAS NOT IGNITED, USE WATER SPRAY
TO DISPERSE THE VAPORS AND TO PROTECT MEN ATTEMPTING TO STOP A LEAK.
WATER SPRAY MAY BE USED TO FLUSH SPILLS AWAY FROM EXPOSURES AND TO
DILUTE SPILLS TO NONFLAMMABLE MIXTURES (NFPA-49 1975).
UNUSUAL FIRE AND EXPLOSION HAZARDS: FIRE FIGHTERS SHOULD WEAR SELFCONTAINED BREATHING APPARATUS IN THE POSITIVE PRESSURE MODE WITH A
FULL FACEPIECE WHEN THERE IS A POSSIBILITY OF EXPOSURE TO SMOKE,
FUMES OR HAZARDOUS DECOMPOSITION PRODUCTS.
MSDS: ALCOHOL USP, ETHYL ALCOHOL, 190 PROOF
Page 5 of 12
*********************************************************************
6.
REACTIVITY DATA:
STABILITY:
UNSTABLE:
STABLE:
X
INCOMPATIBILITY (MATERIALS TO AVOID): CONTACT WITH ACETYL CHLORIDE
AND A WIDE RANGE OF OXIDIZING AGENTS MAY REACT VIOLENTLY.
* FOR PURE ETHYL ALCOHOL
HAZARDOUS DECOMPOSITION OF BY-PRODUCTS: CARBON OXIDES AND
FORMALDEHYDE MAY FORM WHEN HEATED TO DECOMPOSITION.
HAZARDOUS POLYMERIZATION:
MAY OCCUR:
7.
WILL NOT OCCUR:
X
SPILL OR LEAK PROCEDURES:
STEPS TO BE TAKEN IN CASE MATERIAL IS RELEASED OR SPILLED: AVOID
UNCONTROLLED RELEASES OF THIS MATERIAL. WHERE SPILLS ARE POSSIBLE, A
COMPREHENSIVE SPILL RESPONSE PLAN SHOULD BE DEVELOPED AND
IMPLEMENTED. WEAR APPROPRIATE RESPIRATORY PROTECTION AND PROTECTIVE
CLOTHING AS DESCRIBED IN SPECIAL PROTECTION INFORMATION. CONTAIN
SPILLED MATERIAL. TRANSFER TO SECURE CONTAINERS. WHERE NECESSARY,
COLLECT USING ABSORBENT MEDIA. IN THE EVENT OF AN UNCONTROLLED
RELEASE OF THIS MATERIAL, THE USER SHOULD DETERMINE IF THE RELEASE IS
REPORTABLE UNDER APPLICABLE LAWS AND REGULATIONS.
WASTE DISPOSAL METHODS:
8.
OBSERVE ALL FEDERAL AND STATE REGULATIONS
SPECIAL PROTECTION INFORMATION:
RESPIRATORY PROTECTION (SPECIFY TYPE): WHERE EXPOSURE IS LIKELY TO
EXCEED ACCEPTABLE CRITERIA, USE NIOSH/MSHA APPROVED RESPIRATORY
PROTECTION EQUIPMENT. RESPIRATORS SHOULD BE SELECTED BASED ON THE
FORM AND CONCENTRATION OF CONTAMINANT IN AIR AND IN ACCORDANCE WITH
OSHA (29 CFR 1910.134).
VENTILATION:
LOCAL EXHAUST:
OTHER:
X
MECHANICAL:
PROTECTIVE GLOVES: WEAR GLOVES WHICH ARE IMPERVIOUS TO THE PRODUCT
FOR THE DURATION OF THE ANTICIPATED EXPOSURE IF THERE IS POTENTIAL
FOR PROLONGED OR REPEATED SKIN CONTACT.
EYE PROTECTION:
WEAR SAFETY GLASSES MEETING THE SPECIFICATIONS OF
ANSI STANDARD Z87.1 WHERE NO CONTACT WITH THE EYE IS ANTICIPATED.
CHEMICAL SAFETY GOGGLES MEETING THE SPECIFICATIONS OF ANSI STANDARD
Z87.1 SHOULD BE WORN WHENEVER THERE IS THE POSSIBILITY OF SPLASHING
OR OTHER CONTACT WITH THE EYES.
MSDS: ALCOHOL USP, ETHYL ALCOHOL, 190 PROOF
Page 6 of 12
*********************************************************************
8.
SPECIAL PROTECTION INFORMATION (CONT):
OTHER PROTECTIVE EQUIPMENT: PROTECTIVE CLOTHING WHICH IS IMPERVIOUS
TO THE PRODUCT FOR THE DURATION OF THE ANTICIPATED EXPOSURE IF THERE
IS POTENTIAL FOR PROLONGED OR REPEATED SKIN CONTACT.
9.
SPECIAL PRECAUTIONS:
PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE: PROTECT CONTAINER
AGAINST PHYSICAL DAMAGE. DETACHED OR OUTSIDE STORAGE IS PREFERRED.
INSIDE STORAGE SHOULD BE IN AN NFPA APPROVED FLAMMABLE LIQUID STORAGE
ROOM OR CABINET. ALL IGNITION SHOULD BE ELIMINATED. SMOKING SHOULD
BE PROHIBITED IN STORAGE AREAS. ELECTRICAL INSTALLATIONS SHOULD BE
IN ACCORDANCE WITH ARTICLE 501 OF THE NATIONAL ELECTRICAL CODE. NFPA
30, FLAMMABLE AND COMBUSTIBLE LIQUIDS CODE, SHOULD BE FOLLOWED FOR
ALL STORAGE AND HANDLING. FREQUENT CAREFUL LEAKAGE INSPECTIONS
SHOULD BE DONE. AUTOMATIC SPRINKLER SYSTEM SHOULD BE PROVIDED.
ISOLATE FROM OXIDIZERS, CHEMICALS CAPABLE OF SPONTANEOUS HEATING,
MATERIALS REACTING WITH AIR OR MOISTURE TO LIBERATE HEAT, IGNITION
SOURCES AND EXPLOSIVES. CONSULT LOCAL FIRE CODES FOR ADDITIONAL
STORAGE INFORMATION.
WHEN CONTENTS ARE BEING TRANSFERRED, THE METALLIC CONTAINER MUST BE
BONDED TO THE RECEIVING CONTAINER AND GROUNDED TO AVOID STATIC
DISCHARGES. NEVER USE PRESSURE TO EMPTY. REPLACE CLOSURE SECURELY
AFTER EACH OPENING.
KEEP MATERIAL PACKAGED IN DRUMS OR BOTTLES OUT OF SUN AND AWAY FROM
HEAT. REMOVE CLOSURE CAREFULLY; INTERNAL PRESSURE MAY BE PRESENT.
KEEP CLOSURE UP TO PREVENT LEAKAGE.
CONTAINER HAZARDOUS WHEN EMPTY. SINCE EMPTIED CONTAINERS RETAIN
RESIDUAL PRODUCT (VAPOR AND LIQUID), ALL PRECAUTIONS DESCRIBED ON
THIS MSDS MUST BE OBSERVED.
CAUTION: FOR MANUFACTURING, PROCESSING, REPACKING OR INDUSTRIAL USE.
NOT FOR HOUSEHOLD USE.
OTHER PRECAUTIONS:
10.
OTHER INFORMATION:
*********************************************************************
The information herein is given in good faith but no warranty,
expressed or implied, is made.
Page 7 of 12
*********************************************************************
MATERIAL SAFETY DATA SHEET
HELENA LABORATORIES
1530 Lindbergh Dr./P.O. Box 752
Beaumont, TX 77704-0752
USA Toll Free 800-231-5663
*********************************************************************
DATE PREPARED: 1/16/1992
REVISION:
3
*********************************************************************
1.
IDENTIFICATION:
PRODUCT NAME:
HYDROGEN PEROXIDE SOLUTIONS
CAS #.:
CHEMICAL FAMILY:
MOLECULAR FORMULA:
MOLECULAR WEIGHT:
7722-84-1
PEROXIDE
H2-02
34.02
SYNONYMS: HYDROGEN PEROXIDE SOLUTION, 30-50% * STCC 4918776 * UN
2014 * H-323 * H-325 * H-327 * H-341 * ACC11189 *
2.
HAZARDOUS INGREDIENTS:
CHEMICAL NAME/COMMON NAME
CAS #
HYDROGEN PEROXIDE
3.
%
EXPOSURE LIMITS
OSHA PEL
ACGIH TLV
30-50%
1 PPM
(1.4 MG/M3)
1 PPM
(1.4 MG/M3)
PHYSICAL DATA:
BOILING POINT:
223°F (106°C)
VAPOR PRESSURE (MM HG.):
25 AT 30°C
VAPOR DENSITY (AIR = 1):
SPECIFIC GRAVITY (H20 = 1):
MELTING POINT:
1.2
1.1
-13°F (-25°C)
SOLUBILITY IN WATER:
SOLUBLE
APPEARANCE AND ODOR: COLORLESS, CLEAR WATER-LIKE LIQUID/SLIGHTLY
SHARP ODOR AND BITTER TASTE
NA = Not Applicable
NL = Not Listed
NE = Not Established
NIF = No Information Found
MSDS: HYDROGEN PEROXIDE SOLUTION
Page 8 of 12
*********************************************************************
4.
HEALTH HAZARD DATA:
PRIMARY ROUTE(S) OF ENTRY:
INHALATION? YES
CARCINOGENICITY:
NTP?
NO
SKIN?
YES
IARC?
NO
INGESTION?
YES
ACUTE EFFECT OF OVEREXPOSURE:
EYES:
CORROSIVE. VAPORS MAY CAUSE IRRITATION, REDNESS,
PAIN AND BLURRED VISION. DIRECT CONTACT WITH
LIQUID MAY CAUSE CORNEAL BURNS AND POSSIBLE
BLINDNESS.
SKIN:
CORROSIVE. MAY CAUSE IRRITATION, PAIN, BLEACHING
OF THE SKIN AND HAIR, AND ON PROLONGED CONTACT WITH
LIQUID, BURNS.
INHALATION:
CORROSIVE. 75 PPM IS IMMEDIATELY DANGEROUS TO LIFE
AND HEALTH. MAY CAUSE IRRITATION AND INFLAMMATION
OF RESPIRATORY TRACT, SORE THROAT, COUGHING,
DYSPNEA, LABORED BREATHING AND DELAYED PULMONARY
EDEMA.
INGESTION:
CORROSIVE/LIMITED ANIMAL CARCINOGEN. MAY CAUSE
SORE THROAT, FOCAL AND DIFFUSE BURNS OF THE
ESOPHAGUS, ABDOMINAL PAIN, CHEST PAIN, VOMITING,
DIARRHEA AND DISTENTION AND DAMAGE OF THE
ESOPHAGUS, STOMACH OR ABDOMEN DUE TO RELEASE OF
OXYGEN.
CHRONIC EFFECTS OF EXPOSURE:
EYE:
MAY CAUSE CONJUNCTIVITIS AND LACRIMATION.
SKIN:
REPEATED OR PROLONGED EXPOSURE MAY CAUSE BLEACHING
OF THE HAIR, DERMATITIS, IN SOME INDIVIDUALS,
ECZEMA.
INHALATION:
REPEATED OR PROLONGED EXPOSURE MAY CAUSE SNEEZING,
LACRIMATION AND BLEACHING OF HAIR.
INGESTION:
ORAL ADMINISTRATION IN MICE HAS RESULTED IN
ADENOMAS AND CARCINOMAS OF THE DUODENUM.
TOXICITY DATA:
ORL-MAN LDLO 1429 MG/KG
MSDS: HYDROGEN PEROXIDE SOLUTION
Page 9 of 12
*********************************************************************
4.
HEALTH HAZARD DATA (CONT)
EMERGENCY AND FIRST AID PROCEDURES:
5.
EYE CONTACT:
WASH EYES IMMEDIATELY WITH LARGE AMOUNTS OF
WATER, FOR AT LEAST 15-20 MINUTES, OCCASIONALLY
LIFTING UPPER AND LOWER LIDS, UNTIL NO EVIDENCES
OF CHEMICAL REMAINS. CONTINUE IRRIGATING WITH
NORMAL SALINE UNTIL THE pH HAS RETURNED TO NORMAL
(30-60 MINUTES). COVER WITH STERILE BANDAGES.
GET MEDICAL ATTENTION IMMEDIATELY.
SKIN CONTACT:
REMOVE CONTAMINATED CLOTHING AND SHOES
IMMEDIATELY. WASH AFFECTED AREA WITH SOAP OR
MILD DETERGENT AND LARGE AMOUNTS OF WATER UNTIL
NO EVIDENCE OF CHEMICAL REMAINS (AT LEAST 15-20
MINUTES). IN CASE OF CHEMICAL BURNS, COVER AREA
WITH STERILE, DRY DRESSING, BANDAGE SECURELY, BUT
NOT TOO TIGHTLY. GET MEDICAL ATTENTION
IMMEDIATELY.
INHALATION:
REMOVE FROM EXPOSURE AREA TO FRESH AIR
IMMEDIATELY. IF BREATHING HAS STOPPED, GIVE
ARTIFICIAL RESPIRATION. MAINTAIN AIRWAY AND
BLOOD PRESSURE AND ADMINISTER OXYGEN IF
AVAILABLE. KEEP AFFECTED PERSON WARM AND AT
REST. TREAT SYMPTOMATICALLY AND SUPPORTIVELY.
ADMINISTRATION OF OXYGEN SHOULD BE PERFORMED BY
QUALIFIED PERSONNEL. GET MEDICAL ATTENTION
IMMEDIATELY.
INGESTION:
IF THE PERSON IS CONSCIOUS AND NOT CONVULSING,
GIVE 2-4 GLASSES OF WATER TO DILUTE THE CHEMICAL.
USE GASTRIC TUBE TO RELIEVE THE PRESSURE CAUSED
BY EVOLVED OXYGEN (DREISBACH, HANDBOOK OF
POISONING 12TH EDITION). TREAT SYMPTOMATICALLY
AND SUPPORTIVELY. INTUBATION SHOULD BE PERFORMED
BY QUALIFIED MEDICAL PERSONNEL. GET MEDICAL
ATTENTION IMMEDIATELY.
FIRE AND EXPLOSION HAZARD DATA:
FLASH POINT (METHOD USED):
FLAMMABLE LIMITS:
NON-COMBUSTIBLE
LEL
NA
UEL
NA
EXTINGUISHING MEDIA: WATER ONLY, NO DRY CHEMICAL, CARBON DIOXIDE OR
HALON. FOR LARGER FIRES, FLOOD AREA WITH WATER FROM A DISTANCE.
SPECIAL FIRE FIGHTING PROCEDURES: MOVE CONTAINER FROM FIRE AREA IF
POSSIBLE WITHOUT RISK. APPLY COOLING WATER TO SIDES OF CONTAINERS
THAT ARE EXPOSED TO FLAMES UNTIL WELL AFTER FIRE IS OUT. STAY AWAY
MSDS: HYDROGEN PEROXIDE SOLUTION
Page 10 of 12
*********************************************************************
5.
FIRE AND EXPLOSION HAZARD DATA (CONT):
FROM ENDS OF TANKS. FOR MASSIVE FIRE IN CARGO AREA, USE UNMANNED
HOSE HOLDER OR MONITOR NOZZLES; IF THIS IS IMPOSSIBLE, WITHDRAW FROM
AREA AND LET FIRE BURN. USE WATER IN FLOODING AMOUNTS AS A FOG.
COOL CONTAINERS WITH FLOODING QUANTITIES OF WATER, APPLY FROM AS FAR
A DISTANCE AS POSSIBLE. AVOID BREATHING TOXIC VAPORS, KEEP UPWIND.
UNUSUAL
EXPOSED
HEATED,
BURNING
ORGANIC
VIOLENT
6.
FIRE AND EXPLOSION HAZARDS: NEGLIGIBLE FIRE HAZARD WHEN
TO HEAT OR FLAME. OXIDIZERS DECOMPOSE, ESPECIALLY WHEN
TO YIELD OXYGEN OR OTHER GASES WHICH WILL INCREASE THE
RATE OF COMBUSTIBLE MATTER. CONTACT WITH EASILY OXIDIZABLE,
OR OTHER COMBUSTIBLE MATERIALS MAY RESULT IN IGNITION,
COMBUSTION OR EXPLOSION.
REACTIVITY DATA:
STABILITY:
UNSTABLE:
STABLE:
X
INCOMPATIBILITY (MATERIALS TO AVOID):
EXPLOSION
EXPLOSIVE IGNITION
POSSIBLE EXPLOSION
VIOLENT REACTION
VIOLENT DECOMPOSITION
DECOMPOSITION
POSSIBLE DECOMPOSITION
IGNITION AND POSSIBLE
EXPLOSION
- ACETONE, DIMETHYL BENZYLCARBINOL AND
SULFURIC ACID, 2-METHYL-1-PHENYL-2PROPANOL AND SULFURIC ACID, PLATINUM,
KETONES AND NITRIC ACID, ORGANIC
MATTER, THIODIGLYCOL AND ACETONE ON
HEATING, GLYCERIN, ACETIC ACID AND NHETEROCYCLES, CHLOROSULFONIC ACID,
FORMIC ACID AND METABORIC ACID,
SULFURIC ACID ON EVAPORATION, VINYL
ACETATE AND OSMIUM TETRAOXIDE.
- LITHIUM TETRAHYDROALUMINATE.
- ACETAL AND ACETIC ACID, N-BUTANOL AND
SULFURIC ACID, FORMIC ACID AND ORGANIC
SUBSTANCES, SILVER, POWDERED MANGANESE
DIOXIDE, FERRIC SULFATE AND 2METHYLPYRIDINE AND SULFURIC ACID,
TETRAHYDROTHIOPHENE.
- DIPHOSPHOROUS PENTOXIDE, POTASSIUM
PERMANGANATE, LEAD DIOXIDE, LEAD
MONOXIDE, POTASSIUM, SODIUM,
PHOSPHORUS(V) OXIDE.
- BRASS, BRONZE, CARBON, CHROMIUM,
COPPER, IRON, LEAD, MERCURIC OXIDE,
MERCUROUS OXIDE, MAGNESIUM, MANGANESE,
MANGANESE DIOXIDE, SILVER,
BENZENSULPHONIC ANHYDRIDE.
- HYDROGEN SESENIDE, SODIUM IODATE.
- NITROGENOUS BASES.
- ACETIC ACID ON HEATING.
MSDS: HYDROGEN PEROXIDE SOLUTION
Page 11 of 12
*********************************************************************
6.
REACTIVITY DATA (CONT):
IGNITION
RED LUMINESCENCE
POSSIBLE IGNITION
INTENSE EXOTHERMIC
REACTION
VIGOROUS REACTION
FORMATION OF EXPLOSIVE
COMPOUND
FORMATION OF POSSIBLE
EXPLOSIVE COMPOUND.
- UNSYM-DIMETHYL HYDRAZINE, FURFURYL
ALCOHOL, HYDRAZINE AND NITRIC ACID,
MANGANESE, SILVER, CELLULOSE,
CHARCOAL, ALUMINUM ISOPROPOXIDE AND
HEAVY METAL SALTS, WOOD.
- CHLORINE AND POTASSIUM HYDROXIDE.
- PHOSPHORUS
- STAMMOUS CHLORIDE, APHENYLSELENOKETONES.
- ANTIMONY TRISULFIDE, ARSENIC
TRISULFIDE, CUPRIC SULFIDE, LEAD
SULFIDE, MOLYBDENUM DISULFIDE, FERROUS
SULFIDE.
- ALCOHOLS, ESPECIALLY ETHYL,
ACETALDEHYDE AND DESICCANTS, KETONES
AND NITRIC ACID, NITRIC ACID AND
THIOUREA, GADOLINIUM HYDROXIDE, 2METHYL-2-PROPENYL TETRAHYDROPYRANYL
ETHER AND SODIUM SULPHITE, KETENE,
LEAD AND TRIOXANED.
- NITRIC ACID (> 50%)
HAZARDOUS DECOMPOSITION OF BY-PRODUCTS: THERMAL DECOMPOSITION
RELEASES FLAMMABLE OXYGEN AND HEAT. REACTION BECOMES SELF-SUSTAINING
AT 141°C. DECOMPOSITION IS ACCELERATED BY AGITATION, CONTACT WITH
ROUGH SURFACES, ALKALIS, FINELY DIVIDED METALS, AND MANY OTHER
SUBSTANCES.
HAZARDOUS POLYMERIZATION:
MAY OCCUR:
7.
WILL NOT OCCUR:
X
SPILL OR LEAK PROCEDURES:
STEPS TO BE TAKEN IN CASE MATERIAL IS RELEASED OR SPILLED: KEEP
COMBUSTIBLES (WOOD, PAPER, OIL, ETC.) AWAY FROM SPILLED MATERIAL, DO
NOT TOUCH MATERIAL. STOP LEAK IF POSSIBLE WITHOUT RISK. USE WATER
SPRAY TO REDUCE VAPORS. DO NOT GET WATER INSIDE CONTAINER. FOR
SMALL DRY SPILLS, WITH CLEAN SHOVEL PLACE MATERIAL INTO CLEAN, DRY
CONTAINER AND COVER. MOVE CONTAINERS FROM SPILL AREA. FOR SMALL
LIQUID SPILLS, FLUSH AREA WITH FLOODING AMOUNTS OF WATER. FOR LARGER
SPILLS, DIKE FAR AHEAD OF SPILL FOR LATER DISPOSAL. KEEP UNNECESSARY
PEOPLE AWAY. ISOLATE HAZARD AREA AND DENY ENTRY.
THE SUPERFUND AMENDMENTS AND REAUTHORIZATION ACT (SARA) SECTION 304
REQUIRES THAT A RELEASE GREATER THAN THE REPORTABLE QUANTITY (1
POUND) FOR THIS SUBSTANCE BE IMMEDIATELY REPORTED TO THE LOCAL
EMERGENCY PLANNING COMMITTEE AND THE STATE EMERGENCY RESPONSE
MSDS: HYDROGEN PEROXIDE SOLUTION
Page 12 of 12
*********************************************************************
7.
SPILL OR LEAK PROCEDURES (CONT)
COMMISSION (40 CFR 355.40). IF THE RELEASE OF THIS SUBSTANCE IS
REPORTABLE UNDER CERCLA SECTION 103, THE NATIONAL RESPONSE CENTER
MUST BE NOTIFIED IMMEDIATELY (40 CFR 302.6).
WASTE DISPOSAL METHODS:
REGULATIONS.
8.
OBSERVE ALL FEDERAL, STATE AND LOCAL
SPECIAL PROTECTION INFORMATION:
RESPIRATORY PROTECTION (SPECIFY TYPE): THE SPECIFIC RESPIRATOR
SELECTED MUST BE BASED ON CONTAMINATION LEVELS FOUND IN THE WORK
PLACE, MUST NOT EXCEED THE WORKING LIMITS OF THE RESPIRATOR AND BE
JOINTLY APPROVED BY NIOSH/MSHA.
VENTILATION:
LOCAL EXHAUST:
OTHER:
X
MECHANICAL:
PROTECTIVE GLOVES:
APPROPRIATE PROTECTIVE GLOVES TO PREVENT CONTACT.
EYE PROTECTION:
SPLASH-PROOF OR DUST-RESISTANT SAFETY GOGGLES.
OTHER PROTECTIVE EQUIPMENT: IMPERVIOUS CLOTHING TO PREVENT REPEATED
OR PROLONGED SKIN CONTACT. EYE BATH.
9.
SPECIAL PRECAUTIONS:
PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE:
INCOMPATIBLE SUBSTANCES.
OTHER PRECAUTIONS:
10.
STORE AWAY FROM
NA
OTHER INFORMATION:
NA
*********************************************************************
The information herein is given in good faith but no warranty,
expressed or implied, is made.
Page 1 of 2
MATERIAL SAFETY DATA SHEET
1. PRODUCT AND COMPANY IDENTIFICATION
Product Identifier:
DeRoyal Solidifier
MSDS Number:
MSDS-002
Product Description: DeRoyal Solidifier is a granular powder used to solidify medical waste.
Product Numbers:
71-1200, 71-1500, 71-2005, 71-2500, 71-3000, 71-9000, 71-18000, 71-0500, 71-1000
COMPANY PROFILE:
DeRoyal Industries, Inc.
200 DeBusk Lane
Powell, TN 37849
Information: (800) 251-9864
EMERGENCY PHONE: CHEMTREC 24 hrs.
USA: 1 (800) 424 - 9300
Outside USA: 1 (703) 527 - 3887
2. COMPOSITION/INFORMATION ON INGREDIENTS
Components
CAS Registry #
Sodium polyacrylate, lightly crosslinked
Sodium polyacrylate, lightly crosslinked
9033-79-8
9003-04-7
PEL
TLV-TWA
TLV-STEL
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
mg/m3
mg/m3
mg/m3
Notes: N.A. = Not Applicable
3. HAZARDS IDENTIFICATION
Primary routes of entry
Eye
Inhalation
Carcinogen listed in
Skin
Ingestion
NTP
IARC
OSHA
Not Listed
Potential health effects:
Eye Contact: May cause irritation
Ingestion: May cause gastric disturbances
Inhalation: May cause irritation
Skin Contact: May cause irritation
4. FIRST AID MEASURES
Eye Contact: Flush with large quantity of water, consult physician.
Ingestion: If swallowed, dilute with water and immediately induce vomiting. Never give fluids or induce vomiting if the
victim is unconscious or having convulsions. Get immediate medical attention.
Inhalation: Move to fresh air, consult physician.
Skin Contact: If irritation occurs, remove contaminated clothing and wash affected areas with soap and water. If
irritation persists, consult physician.
5. FIRE FIGHTING MEASURES
Flash Point: Not established
Method: N.A.
Autoignition Temperature: Not established
Flammable Limits: Not established
Extinguishing Media: Water, carbon dioxide, dry chemical or halon
Special Fire Fighting Procedures: Wear positive pressure self-contained breathing apparatus. Becomes slippery
when wet. Under certain confined conditions, a fine dust of this material in air may cause a dust explosion if ignited.
6. ACCIDENTAL RELEASE MEASURES
Spill or Leak Procedures: Vacuum, using HEPA filter equipped system, if possible, to avoid generating airborne
dust. Avoid adding water, the product will become slippery when wet.
7. HANDLING AND STORAGE
Handling Precautions: Avoid breathing powder. Avoid eye and skin contact. Store in tightly closed container.
Storage Precautions: Store in cool, dry place.
DeRoyal Solidifier
Page 2 of 2
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Engineering Controls: Local exhaust or mechanical, as appropriate.
Personal protection
Eyes: Use of safety goggles is recommended.
3
Respirator: Use NISOH/MSHA approved respirator with high efficiency filter for particulate levels above 0.05 mg/m .
Unnecessary in normal use.
Skin: Impervious rubber gloves
Other: None required in normal use conditions.
Work/Hygienic Practices: Use good housekeeping practices.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance: Off white, granular powder
Vapor Pressure: N.A.
Vapor Density (air=1): N.A.
Specific Gravity: Not established
Percent Volatility (By wt): N.A.
Odor: Odorless
Solubility in Water: N.A.
Evaporation Rate (n-butylacetate = 1): N.A.
Boiling Point: N.A.
HMIS Classification: Health: 1;Flammability: 0; Reactivity: 0
10. STABILITY AND REACTIVITY
General: Stable
Incompatible Materials: Strong oxidizing agents
Conditions to Avoid: None known
Hazardous Decomposition/Hazardous Combustion: CO, CO2 and NOX hydrocarbons
Hazardous Polymerization: Will not occur
11. TOXICOLOGICAL INFORMATION
Carcinogenicity
IARC: No
NTP: No
OSHA: No
LD50: Not established
LC50: Not established
12. ECOLOGICAL INFORMATION
This section is subject to future development.
13. DISPOSAL CONSIDERATIONS
Waste Disposal Method: Dispose of in accordance with all Federal, State and Local environmental regulations.
14. TRANSPORT INFORMATION
Department of Transportation - Classification: N.A.
Department of Transportation - Identification number: N.A.
15. REGULATORY INFORMATION
CERCLA (Comprehensive Environmental Response Compensation and Liability Act): No reportable quantity.
OSHA Hazard Communication Standard, 29 CFR 1910.1200: All products are listed.
SARA Title III (Superfund Amendments and Reauthorization Act): No listed ingredient.
TSCA (Toxic Substances Control Act): All products are listed.
The information in this Material Safety Data Sheet meets the requirements of the United States Occupational Safety and
Health Act and regulations promulgated thereunder (29 CFR 1910.1200 ET.SEQ.).
16. OTHER INFORMATION
Date of Original Preparation: 03/09/2000
Revision Date: 04/28/2004
Prepared by:
Riley N. Kinman, Ph.D., P.E.
Approved by: Wendy Riggs, DeRoyal Industries, Inc.
Notice: The information presented herein is based on data considered to be accurate as of the date of preparation of this Material
Safety Data Sheet. However, no warranty or representation, express or implied, is made as to the accuracy or completeness of
the foregoing data and safety information, nor is any authorization given or implied to practice any patented invention without a
license. In addition, no responsibility can be assumed by vendor for any damage or injury resulting from abnormal use, from any
failure to adhere to recommended practices, or from any hazards inherent in the nature of the product.
Material Safety Data Sheet
Dichloromethane
ACC# 14930
Section 1 - Chemical Product and Company Identification
MSDS Name: Dichloromethane
Catalog Numbers: S80084, S80084-1, S80084-2SPEC, S80084HPLC, S80084SPEC,
23FD37500, BP1186-4, BP1186POP19, BP1186POP20, BP1186POP50, BP1186SS-19,
BP1186SS-200, BP1186SS-28, BP1186SS-50, BP2608-100, D1381, D1384, D138SK4,
D142-4, D142POP19, D142POP200, D142POP50, D142RS-19, D142RS115, D142RS200,
D142RS28, D142RS50, D142SS-115, D142SS-200, D142SS-28, D142SS-50, D142SS19,
D143-1, D143-4, D143J1, D143N219, D143NB219, D143POP19, D143POP200,
D143POP28, D143POP50, D143POPN19, D143RS-19, D143RS115, D143RS200,
D143RS28, D143RS50, D143SK-1, D143SK-4, D143SK4LC, D143SS-115, D143SS-200,
D143SS-28, D143SS-50, D143SS19, D149-1, D149POP19, D149POP200, D149POP50,
D149RS-19, D149RS-200, D149RS-50, D149SS19, D149SS200, D149SS50, D150-1,
D150-4, D150J-4, D150SK-1, D150SK-4, D151-1, D151-4, D151POP19, D151POP200,
D151POP50, D151RS-19, D151RS-200, D151RS-28, D151RS-50, D151RS115, D151SS115, D151SS-200, D151SS-28, D151SS-50, D151SS19, D154-4, D1544LC, D158-4, D351, D35-4, D37-1, D37-20, D37-200, D37-4, D37-500, D37200LC, D37FB-115, D37FB-19,
D37FB-200, D37FB-50, D37POP19, D37POP200, D37POP50, D37POPB19, D37POPB200,
D37POPB50, D37RB-115, D37RB-19, D37RB-200, D37RB-50, D37RS-115, D37RS-200,
D37RS-28, D37RS-50, D37RS19, D37SK-4, D37SS-115, D37SS-200, D37SS-28, D37SS50, D37SS19, NC9905243, NC9964976
Synonyms: Methylene chloride; Methane dichloride; Methylene bichloride; Methylene
dichloride; Dichloromethane; DCM.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
75-09-2
Chemical Name
Methylene chloride
Hazard Symbols: XN
Percent
EINECS/ELINCS
>99.5
200-838-9
Risk Phrases: 40
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless liquid. This substance has caused adverse reproductive and fetal
effects in animals. Potential cancer hazard. Warning! Causes eye and skin irritation.
Causes respiratory tract irritation. Harmful if swallowed. May be harmful if inhaled. May
cause central nervous system effects. Methylene chloride is metabolically converted to
carbon monoxide after systemic absorption, which yields increased concentrations of
carboxyhemoglobin in the blood. May cause kidney damage.
Target Organs: Blood, kidneys, heart, central nervous system, liver, lungs, pancreas.
Potential Health Effects
Eye: Contact with eyes may cause severe irritation, and possible eye burns.
Skin: May be absorbed through the skin. Causes irritation with burning pain, itching, and
redness. Prolonged exposure may result in skin burns.
Ingestion: Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May
cause kidney damage. May cause central nervous system depression, characterized by
excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages
may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
May cause carboxyhemoglobinemia.
Inhalation: Inhalation of high concentrations may cause central nervous system effects
characterized by nausea, headache, dizziness, unconsciousness and coma. Causes
respiratory tract irritation. May cause narcotic effects in high concentration. Vapors may
cause dizziness or suffocation. May cause blood changes. Overexposure may cause an
increase in carboxyhemoglobin levels in the blood. Can produce delayed pulmonary
edema. Because of its high volatility, airborne concentrations of methylene c hloride can
accumulate in poorly ventilated areas. Odor is a poor indi cator of possibly dangerous air
concentrations of methylene chloride.
Chronic: Possible cancer hazard based on tests with laboratory animals. Prolonged or
repeated skin contact may cause dermatitis. May cause reproductive and fetal effects.
Laboratory experiments have resulted in mutagenic effects. Chronic exposure may cause
lung, liver, and pancreatic tumors. May cause conjunctivitis and/or corneal burns.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid.
Skin: In case of contact, flush skin with plenty of water. Remove contaminated clothing
and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion: If swallowed, do not induce vomiting unless directed to do so by medical
personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use
water spray to keep fire-exposed containers cool. No flash point in conventional closed
tester, but forms flammable vapor-air mixtures in larger volumes and may be an
explosion hazard in a confined space.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate
foam.
Flash Point: Not applicable.
Autoignition Temperature: 556 deg C ( 1,032.80 deg F)
Explosion Limits, Lower:13 vol %
Upper: 23 vol %
NFPA Rating: (estimated) Health: 2; Flammability: 1; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Avoid runoff into storm sewers and ditches which lead to
waterways. Clean up spills immediately, observing precautions in the Protective
Equipment section. Remove all sources of ignition. Provide ventilation.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed.
Keep away from heat, sparks and flame. Use only with adequate ventilation. Avoid
breathing vapor or mist.
Storage: Store in a tightly closed container. Keep from contact with oxidizing materials.
Store in a cool, dry, well-ventilated area away from incompatible substances. Store below
40°C. Keep away from active metals.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name
Methylene chloride
ACGIH
50 ppm TWA
NIOSH
OSHA - Final PELs
2300 ppm IDLH
25 ppm TWA (8 hr);
125 ppm STEL (15
min); 12.5 ppm Action
Level (See 29 CFR
1910 .1052)
OSHA Vacated PELs: Methylene chloride: 500 ppm TWA
Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: colorless
Odor: ethereal odor - chloroform-like
pH: Not available.
Vapor Pressure: 350 mm Hg @ 20 deg C
Vapor Density: 2.93 (Air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 40 deg C
Freezing/Melting Point:-97 deg C
Decomposition Temperature:Not available.
Solubility: Slightly soluble.
Specific Gravity/Density:1.33 (Water=1)
Molecular Formula:CH2Cl2
Molecular Weight:84.92
Section 10 - Stability and Reactivity
Chemical Stability: Stable at room temperature in closed containers under normal
storage and handling conditions. May form explosive mixtures in atmospheres having
high oxygen content.
Conditions to Avoid: Excess heat, attacks some plastics, rubber, and coatings, confined
spaces, When no water is present, dichloromethane is not corrosive to metals. At high
temperatures and in the presence of water (causing slow decomposition forming HCl),
corrosion of iron, some stainless steels, copper and aluminum can occur..
Incompatibilities with Other Materials: Strong oxidizing agents, strong bases,
chemically active metals.
Hazardous Decomposition Products: Hydrogen chloride, phosgene, carbon monoxide,
carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 75-09-2: PA8050000
LD50/LC50:
CAS# 75-09-2:
Draize test, rabbit, eye: 162 mg Moderate;
Draize test, rabbit, eye: 10 mg Mild;
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, skin: 810 mg/24H Severe;
Draize test, rabbit, skin: 100 mg/24H Moderate;
Inhalation, mouse: LC50 = 14400 ppm/7H;
Inhalation, rat: LC50 = 52 gm/m3;
Oral, mouse: LD50 = 873 mg/kg;
Oral, rat: LD50 = 1600 mg/kg;
Carcinogenicity:
CAS# 75-09-2:
ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to humans
California: carcinogen, initial date 4/1/88
NIOSH: potential occupational carcinogen
NTP: Suspect carcinogen
OSHA: Possible Select carcinogen
IARC: Group 2B carcinogen
Epidemiology: There are few reports of injury despite widespread use of
dichloromethane (ACGIH, 1991). Solvent abuse has led to death (Harbison, 1998).
Teratogenicity: Inhalation, rat: TCLo = 4500 ppm/24H (female 1-17 day(s) after
conception) Effects on Newborn - behavioral.; Inhalation, rat: TCLo = 1250 ppm/7H
(female 6-15 day(s) after conception) Specific Developmental Abnormalities musculoskeletal system and urogenital system.
Reproductive Effects: Reproductive effects have occurred in experimental animals.
Neurotoxicity: No information available.
Mutagenicity: DNA inhibition: Human, Fibroblast = 5000 ppm/1H (Continuous).;
Morphological transformation: Rat, Embryo = 160 umol/L.; DNA damage: Oral, rat =
1275 mg/kg.; Inhalation, mouse: TCLo = 2000 ppm/5H/2Y-C (Tumorigenic Carcinogenic by RTECS criteria--Lungs, Thorax, or Respiration - Tumors).
Other Studies: See actual entry in RTECS for complete information.
Section 12 - Ecological Information
Ecotoxicity: Fish: Bluegill/Sunfish: 230mg/L; 24H; StaticFish: Fathead Minnow: 196mg/
L; 96H; This chemical has a moderate potential to affect some aquatic organisms. It is
resistant to biodegradation, and has a low potential to persist in the aquatic environment.
96-hr. EC50 (loss of equilibrium); Fathead minnow: 99mg/L; 96-hr. EC10: 66.3 mg/L.
Bluegill sunfish: 96-hr. LC50=220 mg/L; Water flea: 24-hr. LC50=2270 mg/L; No
observed effect level:1550 mg/L.
Environmental: Terrestrial: Expected to evaporate from near surface soil into the
atmosphere; expected to leach. Aquatic: Primarily lost by evaporation to the atmosphere
which should take several hours depending on wind and mixing conditions. Atmospheric:
Will degrade by reaction with hydroxyl radicals with a half life of several months. .
Dichloromethane is reported to completely biodegrade under aerobic conditions with
sewage seed or activated sludge between 6 hours to 7 days. Not expected to
bioconcentrate due to its low octanol/water coefficient.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 75-09-2: waste number U080.
Section 14 - Transport Information
US DOT
IATA
RID/ADR
IMO
Canada TDG
Shipping
Name:
DICHLOROMETHANE
Hazard Class: 6.1
6.1
UN Number: UN1593
Packing
Group:
METHYLENE
CHLORIDE
III
UN1593
III
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 75-09-2 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 75-09-2: Effective 10/4/82; Sunset 10/4/92
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 75-09-2: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 75-09-2: acute, chronic.
Section 313
This material contains Methylene chloride (CAS# 75-09-2, 99 5%),which is subject to the
reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 75-09-2 is listed as a hazardous air pollutant (HAP). This material does not contain
any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
CAS# 75-09-2 is listed as a Priority Pollutant under the Clean Water Act. CAS# 75-09-2
is listed as a Toxic Pollutant under the Clean Water Act.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 75-09-2 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
The following statement(s) is(are) made in order to comply with the California
Safe Drinking Water Act: WARNING: This product contains Methylene chloride, a
chemical known to the state of California to cause cancer. California No Significant Risk
Level: CAS# 75-09-2: 200 æg/day NSRL (inhalation); 50 æg/day NSRL (except
inhalation)
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 40 Limited evidence of a carcinogenic effect.
Safety Phrases:
S 23 Do not inhale gas/fumes/vapour/spray.
S 24/25 Avoid contact with skin and eyes.
S 36/37 Wear suitable protective clothing and
gloves.
WGK (Water Danger/Protection)
CAS# 75-09-2: 2
Canada - DSL/NDSL
CAS# 75-09-2 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D1B, D2A.
Canadian Ingredient Disclosure List
CAS# 75-09-2 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 75-09-2: OEL-AUSTRALIA:TWA 100 ppm (350 mg/m3);Carcinogen OELAUSTRIA:TWA 100 ppm (360 mg/m3) OEL-BELGIUM:TWA 50 ppm (174 mg/m3);Ca
rcinogen OEL-CZECHOSLOVAKIA:TWA 500 mg/m3;STEL 2500 mg/m3 OEL-DENMAR
K:TWA 50 ppm (175 mg/m3);Skin;Carcinoge OEL-FINLAND:TWA 100 ppm (350
mg/m3);STEL 250 ppm (870 mg/m3) OEL-FRANCE:TWA 100 ppm (360 mg/m3);ST
EL 500 ppm (1800 mg/m3) OEL-GERMANY:TWA 100 ppm (360 mg/m3);Carcinoge
n OEL-HUNGARY:STEL 10 mg/m3;Carcinogen OEL-JAPAN:TWA 100 ppm (350 mg
/m3) OEL-THE NETHERLANDS:TWA 100 ppm (350 mg/m3);STEL 500 ppm OEL-TH
E PHILIPINES:TWA 500 ppm (1740 mg/m3) OEL-POLAND:TWA 50 mg/m3 OEL-RU
SSIA:TWA 100 ppm;STEL 50 mg/m3 OEL-SWEDEN:TWA 35 ppm (120 mg/m3);STEL
70 ppm (25 mg/m3);Skin OEL-SWITZERLAND:TWA 100 ppm (360 mg/m3);STEL
500 ppm OEL-THAILAND:TWA 500 mg/m3;STEL 1000 mg/m3 OEL-TURKEY:TWA 50
0 ppm (1740 mg/m3) OEL-UNITED KINGDOM:TWA 100 ppm (350 mg/m3);STEL 25
0 ppm OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL I
N NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 4/20/1999
Revision #5 Date: 2/20/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Dimethyl Sulfoxide
ACC# 07770
Section 1 - Chemical Product and Company Identification
MSDS Name: Dimethyl Sulfoxide
Catalog Numbers: S79994REAG, BP231-1, BP231-100, BP231-4, BP D128-500,
D128FB200, D128POP19, D128POP200, D128POP50, D128RB200, D128RS200,
D128RS50, D128SS200, D128SS50, D136-1, D137POP19, D137POP200, D137POP50,
D137SS19, D137SS200, D137SS50, NC9007088, NC9109929, NC9133613, NC91336131/
GNF, NC9136159, NC9152193, NC9161560, NC9162172, NC9170160, NC9529973,
NC9530475, NC9531964, NC9750632, NC9934033, NC9969922, NC9981334,
NC9994436, S67496, XXBP231208LI, XXBP23120BLI, XXBP23120LI, XXBP23120LI/,
XXBP23150ML, XXD128POPB200, XXDMSOHPLC4L, XXDMSOHPLC4LI,
XXDMSOHPLCRS50, XXEP231ET4LI
Synonyms: Methyl sulfoxide; DMSO; Sulfinylbis(methane); Dimethyl sulfoxide.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
67-68-5
Chemical Name
Dimethyl sulfoxide
Percent
EINECS/ELINCS
100
200-664-3
Hazard Symbols: XI
Risk Phrases: 36/37/38
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: clear liquid. May be absorbed through intact skin. Hygroscopic (absorbs
moisture from the air). May cause liver and kidney damage. Causes eye and skin
irritation. Causes respiratory tract irritation. Warning!
Target Organs: Kidneys, liver, eyes, skin, mucous membranes.
Potential Health Effects
Eye: Produces irritation, characterized by a burning sensation, redness, tearing,
inflammation, and possible corneal injury. May cause chemical conjunctivitis.
Skin: May cause irritation with burning pain, itching and redness. Substance is rapidly
absorbed through the skin.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May
cause liver and kidney damage. May cause garlic smell on the breath and body.
Inhalation: May cause respiratory tract irritation. Can produce delayed pulmonary
edema.
Chronic: Prolonged or repeated skin contact may cause dermatitis. May cause liver and
kidney damage. Effects may be delayed.
Section 4 - First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do
NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or
water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT
use mouth-to-mouth resuscitation.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Vapors may form an explosive mixture with air. During a fire, irritating and highly toxic
gases may be generated by thermal decomposition or combustion. Use water spray to
keep fire-exposed containers cool. Vapors may be heavier than air. They can spread
along the ground and collect in low or confined areas. Containers may explode when
heated.
Extinguishing Media: Cool containers with flooding quantities of water until well after
fire is out. Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: 95 deg C ( 203.00 deg F)
Autoignition Temperature: 215 deg C ( 419.00 deg F)
Explosion Limits, Lower:2.6 vol %
Upper: 42 vol %
NFPA Rating: (estimated) Health: 2; Flammability: 1; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Do not flush into a sewer. Clean up spills immediately,
observing precautions in the Protective Equipment section. Provide ventilation.
Section 7 - Handling and Storage
Handling: Avoid contact with eyes, skin, and clothing. Keep container tightly closed.
Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before
reuse.
Storage: Keep away from heat, sparks, and flame. Store in a tightly closed container.
Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area
away from incompatible substances.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits
Chemical Name
Dimethyl sulfoxide
ACGIH
none listed
NIOSH
OSHA - Final PELs
none listed
none listed
OSHA Vacated PELs: Dimethyl sulfoxide: No OSHA Vacated PELs are listed for this
chemical.
Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear
Odor: slight odor - sulfurous odor - garlic-like odor
pH: Not available.
Vapor Pressure: 0.4 mm Hg at 20
Vapor Density: 2.7 (air=1)
Evaporation Rate:Not available.
Viscosity: 1.1cp @ 27 deg C
Boiling Point: 189 deg C
Freezing/Melting Point:18.4 deg C
Decomposition Temperature:> 200 deg C
Solubility: Soluble.
Specific Gravity/Density:1.1010g/cm3
Molecular Formula:C2H6OS
Molecular Weight:78.13
Section 10 - Stability and Reactivity
Chemical Stability: Stable at room temperature in closed containers under normal
storage and handling conditions.
Conditions to Avoid: Excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents, strong acids, strong
bases.
Hazardous Decomposition Products: Carbon monoxide, oxides of sulfur, carbon
dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 67-68-5: PV6210000
LD50/LC50:
CAS# 67-68-5:
Draize test, rabbit, eye: 100 mg;
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, skin: 500 mg/24H Mild;
Oral, mouse: LD50 = 7920 mg/kg;
Oral, rat: LD50 = 14500 mg/kg;
Skin, rat: LD50 = 40 gm/kg;
Carcinogenicity:
CAS# 67-68-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: See actual entry in RTECS for complete information.
Section 12 - Ecological Information
Ecotoxicity: No data available. No information available.
Environmental: Terrestrial: Expected to be mobile in soil, due to its high water
solubility. Some volatilization from dry soil and surfaces may be expected. Aquatic:
Dimethyl sulfoxide disproportionates in water to dimethyl sulfide and dimethyl sulfone, a
reaction catalyzed by light. Atmospheric: Exists primarily in the vapor phase and be
removed by both wet and dry deposition. It will react with photochemically-produced
hydroxyl radicals with a half-life of about 7 hr. DMSO is very difficult to biodegrade.
Physical: No information available.
Other: For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND
EXPOSURE DATA."
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
Hazard Class:
UN Number:
No
information
available.
IATA
RID/ADR
IMO
Canada TDG
No information
available.
Packing Group:
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 67-68-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 67-68-5: acute, flammable.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 67-68-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 67-68-5: 1
Canada - DSL/NDSL
CAS# 67-68-5 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D2B.
Canadian Ingredient Disclosure List
CAS# 67-68-5 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 67-68-5: OEL-RUSSIA:STEL 20 mg/m3 OEL-SWITZERLAND:TWA 50 ppm (
160 mg/m3);Skin
Section 16 - Additional Information
MSDS Creation Date: 12/12/1997
Revision #6 Date: 2/05/2002
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Humco Holding Group, Inc.
7400 Alumax Drive
Texarkana, TX 75501
903-831-7808
EPSOM SALT
DATE ISSUED: 02/23/01
--------------------------------------------------------------------------------------------------------------------------------------SECTION I
IDENTIFICATION
--------------------------------------------------------------------------------------------------------------------------------------Product Name/Trade Name: Epsom Salt
Chemical Names: Magnesium Sulfate,heptahydrate
TSCA CAS Registry No.: 10034-99-8 (Hydrates are considered under TSCA as mixtures of the anhydrous
salt and water)
DOT Hazardous Class: NA
DOT Shipping Name: NA
Emergency Telephone Number: 1-800-424-9300
--------------------------------------------------------------------------------------------------------------------------------------SECTION II
PHYSICAL DATA
--------------------------------------------------------------------------------------------------------------------------------------Appearance & Odor: Colorless transparent crystals. Odorless.
Specific Gravity (liquids only): NA (bulk density is 1.05)
Vapor Pressure (mm Hg @ °F, nonaqueous liquids only): NA
Solubility in Water: Appreciable
pH (nonaqueous liquids only): NA
Boiling Point (°F, nonaqueous liquids only): NA
Vapor Density (nonaqueous liquids only): NA
Evaporation Rate (Butyl Acetate = 100, nonaqueous liquids only): NA
--------------------------------------------------------------------------------------------------------------------------------------SECTION III
FIRE & EXPLOSION DATA
--------------------------------------------------------------------------------------------------------------------------------------Flash Point (°F): NA (material in non-combustible)
Flammable Limits (vapor in air, Vol. %): NA
2
Extinguishing Media: NA
Special Fire Fighting Procedures: Use positive pressure supplies air breathing apparatus.
Unusual Fire & Explosion Hazards: At very high temperatures, magnesium oxide, sulfur dioxide, and sulfur
trioxide may be generated.
--------------------------------------------------------------------------------------------------------------------------------------SECTION IV
REACTIVITY DATA
--------------------------------------------------------------------------------------------------------------------------------------Stability: Stable
Conditions to Avoid: NA
Incompatibility (Materials to Avoid): NA
Hazardous Decomposition Products: At very high temperatures, magnesium oxide, sulfur dioxide, and sulfur
trioxide may be generated.
--------------------------------------------------------------------------------------------------------------------------------------SECTION V
SPILL OR LEAK PROCEDURE
--------------------------------------------------------------------------------------------------------------------------------------Environmental Hazard: No adverse effects known or suspected. Not a listed toxic chemical under SARA
Title III, Section302, 304, or 313.
Spillage: Sweep, scoop, or vacuum discharged material.
Waste Disposal Method: Not a RCRA Hazardous waste. Dissolve in large excess of water and sewer, or
landfill according to local, state, and federal regulations.
--------------------------------------------------------------------------------------------------------------------------------------SECTION VI
HEALTH HAZARDS
--------------------------------------------------------------------------------------------------------------------------------------Inhalation: May cause irritation.
Skin: No adverse effects known or suspected.
Ingestion: Purgative. Causes nausea, vomiting, abdominal cramps, and diarrhea.
Chronic Hazard: No known chronic hazards. Not listed by OSHA, NTP, or IARC as a carcinogen.
Signs & Symptoms of Exposure: Sneezing & dryness of mucous membranes (inhalation). Pain, redness, and
tearing (eye exposure). Nausea, vomiting, abdominal cramps, and diarrhea (ingestion).
Medical Conditions Generally Aggravated by Exposure: Ingestion of large amounts by persons with
impaired renal functions may cause serious systemic effects.
Emergency & First Aid Procedures: Induce vomiting if large amounts are ingested. Call physician.
2
3
--------------------------------------------------------------------------------------------------------------------------------------SECTION VII
SPECIAL PROTECTION INFORMATION
--------------------------------------------------------------------------------------------------------------------------------------Respiratory Protection: NA
Protective Gloves: NA
Eye Protection: Wear safety glasses with side shields or chemical goggles.
Other Protective Equipment: Safety shower and eyewash fountain should be within direct access.
Personal Hygiene: Avoid breathing dust. Wash thoroughly after handling.
Engineering Control: Use with adequate ventilation.
--------------------------------------------------------------------------------------------------------------------------------------SECTION VIII
SUBSTANCES FOR WHICH SANDARDS HAVE BEEN SET
--------------------------------------------------------------------------------------------------------------------------------------OSHA Permissible Exposure Limit or ACGIH Threshold Limit Value have not been established. P.Q.
recommended Ceiling limit 5 mg/m3 Respirable dust.
Exposure Analysis Methods: Respirable sampler or Midget impinger see:
J. Am. Ind. Hyg. Assoc., 28:554 (1967)
This Material Safety Data Sheet is based on a limited review of various files and standard toxicology
handbooks.
This information herein is furnished without warranty of any kind. This information should be used only as a
supplement to information already in your possession concerning this product. The determination of whether
and under what conditions this product should be used by you or your employees is yours to make.
3
Material Safety Data Sheet
95% Ethanol, 190 Proof
ACC# 90969
Section 1 - Chemical Product and Company Identification
MSDS Name: 95% Ethanol, 190 Proof
Catalog Numbers: AC615110010, AC615110040
Synonyms: Ethyl alcohol; Ethyl alcohol anhydrous; Ethyl hydrate; Ethyl hydroxide;
Fermentation alcohol; Grain alcohol; Methylcarbinol; Molasses alcohol; Spirits of wine
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
CAS#
64-17-5
7732-18-5
Chemical Name
Ethyl alcohol
Water
Percent
EINECS/ELINCS
95.0
200-578-6
5.0
231-791-2
Hazard Symbols: F
Risk Phrases: 11
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: Colorless. Flash Point: 16.66 deg C. Flammable liquid and vapor. May
cause central nervous system depression. Causes severe eye irritation. Causes
respiratory tract irritation. Causes moderate skin irritation. This substance has caused
adverse reproductive and fetal effects in humans. Warning! May cause liver, kidney and
heart damage.
Target Organs: Kidneys, heart, central nervous system, liver.
Potential Health Effects
Eye: Causes severe eye irritation. May cause painful sensitization to light. May cause
chemical conjunctivitis and corneal damage.
Skin: Causes moderate skin irritation. May cause cyanosis of the extremities.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May
cause systemic toxicity with acidosis. May cause central nervous system depression,
characterized by excitement, followed by headache, dizziness, drowsiness, and nausea.
Advanced stages may cause collapse, unconsciousness, coma and possible death due to
respiratory failure.
Inhalation: Inhalation of high concentrations may cause central nervous system effects
characterized by nausea, headache, dizziness, unconsciousness and coma. Causes
respiratory tract irritation. May cause narcotic effects in high concentration. Vapors may
cause dizziness or suffocation.
Chronic: May cause reproductive and fetal effects. Laboratory experiments have resulted
in mutagenic effects. Animal studies have reported the development of tumors. Prolonged
exposure may cause liver, kidney, and heart damage.
Section 4 - First Aid Measures
Eyes: Get medical aid. Gently lift eyelids and flush continuously with water.
Skin: Get medical aid. Wash clothing before reuse. Flush skin with plenty of soap and
water.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT
use mouth-to-mouth resuscitation.
Notes to Physician: Treat symptomatically and supportively. Persons with skin or eye
disorders or liver, kidney, chronic respiratory diseases, or central and peripheral nervous
sytem diseases may be at increased risk from exposure to this substance.
Antidote: Replace fluid and electrolytes.
Section 5 - Fire Fighting Measures
General Information: Containers can build up pressure if exposed to heat and/or fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/
NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive
mixture with air. Vapors can travel to a source of ignition and flash back. Will burn if
involved in a fire. Flammable Liquid. Can release vapors that form explosive mixtures at
temperatures above the flashpoint. Use water spray to keep fire-exposed containers cool.
Containers may explode in the heat of a fire.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam.
Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use
straight streams of water.
Flash Point: 16.66 deg C ( 61.99 deg F)
Autoignition Temperature: 363 deg C ( 685.40 deg F)
Explosion Limits, Lower:3.3 vol %
Upper: 19.0 vol %
NFPA Rating: (estimated) Health: 2; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Remove all sources of ignition. Use a spark-proof tool. Provide
ventilation. A vapor suppressing foam may be used to reduce vapors.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Use only in a well-ventilated area. Ground
and bond containers when transferring material. Use spark-proof tools and explosion
proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain
product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly
closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not
pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat,
sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition.
Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a
cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Do
not store near perchlorates, peroxides, chromic acid or nitric acid.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility and a safety shower.
Use adequate general or local exhaust ventilation to keep airborne concentrations below
the permissible exposure limits.
Exposure Limits
Chemical Name
Ethyl alcohol
Water
ACGIH
1000 ppm TWA
none listed
NIOSH
OSHA - Final PELs
1000 ppm TWA; 1900
mg/m3 TWA 3300 ppm
IDLH
1000 ppm TWA; 1900
mg/m3 TWA
none listed
none listed
OSHA Vacated PELs: Ethyl alcohol: 1000 ppm TWA; 1900 mg/m3 TWA Water: No
OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: Colorless
Odor: Mild, rather pleasant, like wine or whis
pH: Not available.
Vapor Pressure: 59.3 mm Hg @ 25 deg C
Vapor Density: 1.59
Evaporation Rate:Not available.
Viscosity: 1.200 cP @ 20 deg C
Boiling Point: 78 deg C
Freezing/Melting Point:-114.1 deg C
Decomposition Temperature:Not available.
Solubility: Miscible.
Specific Gravity/Density:0.790 @ 20°C
Molecular Formula:C2H5OH
Molecular Weight:46.0414
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, ignition sources, excess heat, oxidizers.
Incompatibilities with Other Materials: Strong oxidizing agents, acids, alkali metals,
ammonia, hydrazine, peroxides, sodium, acid anhydrides, calcium hypochlorite, chromyl
chloride, nitrosyl perchlorate, bromine pentafluoride, perchloric acid, silver nitrate,
mercuric nitrate, potassium tert-butoxide, magnesium perchlorate, acid chlorides,
platinum, uranium hexafluoride, silver oxide, iodine heptafluoride, acetyl bromide,
disulfuryl difluoride, tetrachlorosilane + water, acetyl chloride, permanganic acid,
ruthenium (VIII) oxide, uranyl perchlorate, potassium dioxide.
Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 64-17-5: KQ6300000
CAS# 7732-18-5: ZC0110000
LD50/LC50:
CAS# 64-17-5:
Draize test, rabbit, eye: 500 mg Severe;
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, skin: 20 mg/24H Moderate;
Inhalation, mouse: LC50 = 39 gm/m3/4H;
Inhalation, rat: LC50 = 20000 ppm/10H;
Oral, mouse: LD50 = 3450 mg/kg;
Oral, rabbit: LD50 = 6300 mg/kg;
Oral, rat: LD50 = 7060 mg/kg;
Oral, rat: LD50 = 9000 mg/kg;
CAS# 7732-18-5:
Oral, rat: LD50 = >90 mL/kg;
Carcinogenicity:
CAS# 64-17-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 7732-18-5: Not
listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: Ethanol has been shown to produce fetotoxicity in the embry o or fetus
of laboratory animals. Prenatal exposure to ethanol is associated with a distinct pattern of
co ngenital malformations that have collecetively been termed the "fetal alcohol
syndrome".
Teratogenicity: Oral, Human - woman: TDLo = 41 gm/kg (female 41 week(s) after
conception) Effects on Newborn - Apgar score (human only) and Effects on Newborn other neonatal measures or effects and Effects on Newborn - drug dependence.
Reproductive Effects: Intrauterine, Human - woman: TDLo = 200 mg/kg (female 5 day
(s) pre-mating) Fertility - female fertility index (e.g. # females pregnant per # sperm
positive females; # females pregnant per # females mated).
Neurotoxicity: No information available.
Mutagenicity: DNA Inhibition: Human, Lymphocyte = 220 mmol/L.; Cytogenetic
Analysis: Human, Lymphocyte = 1160 gm/L.; Cytogenetic Analysis: Human, Fibroblast =
12000 ppm.; Cytogenetic Analysis: Human, Leukocyte = 1 pph/72H (Continuous).; Sister
Chromatid Exchange: Human, Lymphocyte = 500 ppm/72H (Continuous).
Other Studies: Standard Draize Test(Skin, rabbit) = 20 mg/24H (Moderate) S tandard
Draize Test: Administration into the eye (rabbit) = 500 mg (Severe).
Section 12 - Ecological Information
Ecotoxicity: Fish: Rainbow trout: LC50 = 12900-15300 mg/L; 96 Hr; Flow-through @
24-24.3°CFish: Rainbow trout: LC50 = 11200 mg/L; 24 Hr; Fingerling (Unspecified)
Bacteria: Phytobacterium phosphoreum: EC50 = 34900 mg/L; 5-30 min; Microtox test
When spilled on land it is apt to volatilize, biodegrade, and leach into the ground water,
but no data on the rates of these processes could be found. Its fate in ground water is
unknown. When released into water it will volatilize and probably biodegrade. It would
not be expected to adsorb to sediment or bioconcentrate in fish.
Environmental: When released to the atmosphere it will photodegrade in hours
(polluted urban atmosphere) to an estimated range of 4 to 6 days in less polluted areas.
Rainout should be significant.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
ETHANOL
Hazard Class: 3
UN Number:
UN1170
UN2238
III
Additional
Info:
FLASHPOINT 47 C
Section 15 - Regulatory Information
TSCA
CHLOROTOLUENES
3
Packing Group: II
US FEDERAL
Canada TDG
CAS# 64-17-5 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 64-17-5: acute, chronic, flammable.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 64-17-5 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
WARNING: This product contains Ethyl alcohol, a chemical known to the state of
California to cause birth defects or other reproductive harm. California No Significant Risk
Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
F
Risk Phrases:
R 11 Highly flammable.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 33 Take precautionary measures against static
discharges.
S 7 Keep container tightly closed.
S 9 Keep container in a well-ventilated place.
WGK (Water Danger/Protection)
CAS# 64-17-5: 0
CAS# 7732-18-5: No information available.
Canada - DSL/NDSL
CAS# 64-17-5 is listed on Canada's DSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2A.
Canadian Ingredient Disclosure List
CAS# 64-17-5 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 64-17-5: OEL-AUSTRALIA:TWA 1000 ppm (1900 mg/m3) OEL-BELGIUM:T
WA 1000 ppm (1880 mg/m3) OEL-CZECHOSLOVAKIA:TWA 1000 mg/m3;STEL 5000
mg/m3 OEL-DENMARK:TWA 1000 ppm (1900 mg/m3) OEL-FINLAND:TWA 1000 ppm
(1900 mg/m3);STEL 1250 ppm (2400 mg/m3) OEL-FRANCE:TWA 1000 ppm (190
0 mg/m3);STEL 5000 pp OEL-GERMANY:TWA 1000 ppm (1900 mg/m3) OEL-HUNG
ARY:TWA 1000 mg/m3;STEL 3000 mg/m3 OEL-THE NETHERLANDS:TWA 1000 ppm (
1900 mg/m3) OEL-THE PHILIPPINES:TWA 1000 ppm (1900 mg/m3) OEL-POLAND
:TWA 1000 mg/m3 OEL-RUSSIA:STEL 1000 mg/m3 OEL-SWEDEN:TWA 1000 ppm (
1900 mg/m3) OEL-SWITZERLAND:TWA 1000 ppm (1900 mg/m3) OEL-THAILAND:T
WA 1000 ppm (1900 mg/m3) OEL-TURKEY:TWA 1000 ppm (1900 mg/m3) OEL-UN
ITED KINGDOM:TWA 1000 ppm (1900 mg/m3) JAN9 OEL IN BULGARIA, COLOMBIA
, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNA
M check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 7/27/1999
Revision #4 Date: 1/22/2004
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Ethanol, 200 Proof
ACC# 91677
Section 1 - Chemical Product and Company Identification
MSDS Name: Ethanol, 200 Proof
Catalog Numbers: AC615090000, AC615090010, AC615090020, AC615090040,
AC615095000, AC615100010, AC615100020, AC615101000, A994-1GAL, A994-1PT,
A994-55GAL, A994-5GAL, S540CA4
Synonyms: Ethyl Alcohol; Ethyl Alcohol Anhydrous; Ethyl Hydrate; Ethyl Hydroxide;
Fermentation Alcohol; Grain Alcohol; Methylcarbinol; Molasses Alcohol; Spirits of Wine.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
64-17-5
Chemical Name
Ethyl alcohol
Percent
EINECS/ELINCS
100
200-578-6
Hazard Symbols: F
Risk Phrases: 11
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless clear liquid. Flash Point: 16.6 deg C. Flammable liquid and
vapor. May cause central nervous system depression. Causes severe eye irritation.
Causes respiratory tract irritation. Causes moderate skin irritation. This substance has
caused adverse reproductive and fetal effects in humans. Warning! May cause liver,
kidney and heart damage.
Target Organs: Kidneys, heart, central nervous system, liver.
Potential Health Effects
Eye: Causes severe eye irritation. May cause painful sensitization to light. May cause
chemical conjunctivitis and corneal damage.
Skin: Causes moderate skin irritation. May cause cyanosis of the extremities.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May
cause systemic toxicity with acidosis. May cause central nervous system depression,
characterized by excitement, followed by headache, dizziness, drowsiness, and nausea.
Advanced stages may cause collapse, unconsciousness, coma and possible death due to
respiratory failure.
Inhalation: Inhalation of high concentrations may cause central nervous system effects
characterized by nausea, headache, dizziness, unconsciousness and coma. Causes
respiratory tract irritation. May cause narcotic effects in high concentration. Vapors may
cause dizziness or suffocation.
Chronic: May cause reproductive and fetal effects. Laboratory experiments have resulted
in mutagenic effects. Animal studies have reported the development of tumors. Prolonged
exposure may cause liver, kidney, and heart damage.
Section 4 - First Aid Measures
Eyes: Get medical aid. Gently lift eyelids and flush continuously with water.
Skin: Get medical aid. Wash clothing before reuse. Flush skin with plenty of soap and
water.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT
use mouth-to-mouth resuscitation.
Notes to Physician: Treat symptomatically and supportively. Persons with skin or eye
disorders or liver, kidney, chronic respiratory diseases, or central and peripheral nervous
sytem diseases may be at increased risk from exposure to this substance.
Antidote: Replace fluid and electrolytes.
Section 5 - Fire Fighting Measures
General Information: Containers can build up pressure if exposed to heat and/or fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/
NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive
mixture with air. Vapors can travel to a source of ignition and flash back. Will burn if
involved in a fire. Flammable Liquid. Can release vapors that form explosive mixtures at
temperatures above the flashpoint. Use water spray to keep fire-exposed containers cool.
Containers may explode in the heat of a fire.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam.
Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use
straight streams of water.
Flash Point: 16.6 deg C ( 61.88 deg F)
Autoignition Temperature: 363 deg C ( 685.40 deg F)
Explosion Limits, Lower:3.3 vol %
Upper: 19.0 vol %
NFPA Rating: (estimated) Health: 2; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Remove all sources of ignition. Use a spark-proof tool. Provide
ventilation. A vapor suppressing foam may be used to reduce vapors.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Use only in a well-ventilated area. Ground
and bond containers when transferring material. Use spark-proof tools and explosion
proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain
product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly
closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not
pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat,
sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition.
Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a
cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Do
not store near perchlorates, peroxides, chromic acid or nitric acid.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility and a safety shower.
Use adequate general or local exhaust ventilation to keep airborne concentrations below
the permissible exposure limits.
Exposure Limits
Chemical Name
ACGIH
NIOSH
OSHA - Final PELs
Ethyl alcohol
1000 ppm TWA
1000 ppm TWA; 1900
mg/m3 TWA 3300 ppm
IDLH
1000 ppm TWA; 1900
mg/m3 TWA
OSHA Vacated PELs: Ethyl alcohol: 1000 ppm TWA; 1900 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Clear liquid
Appearance: colorless
Odor: Mild, rather pleasant, like wine or whis
pH: Not available.
Vapor Pressure: 59.3 mm Hg @ 20 deg C
Vapor Density: 1.59
Evaporation Rate:Not available.
Viscosity: 1.200 cP @ 20 deg C
Boiling Point: 78 deg C
Freezing/Melting Point:-114.1 deg C
Decomposition Temperature:Not available.
Solubility: Miscible.
Specific Gravity/Density:0.790 @ 20°C
Molecular Formula:C2H5OH
Molecular Weight:46.0414
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, ignition sources, excess heat, oxidizers.
Incompatibilities with Other Materials: Strong oxidizing agents, acids, alkali metals,
ammonia, hydrazine, peroxides, sodium, acid anhydrides, calcium hypochlorite, chromyl
chloride, nitrosyl perchlorate, bromine pentafluoride, perchloric acid, silver nitrate,
mercuric nitrate, potassium-tert-butoxide, magnesium perchlorate, acid chlorides,
platinum, uranium hexafluoride, silver oxide, iodine heptafluoride, acetyl bromide,
disulfuryl difluoride, tetrachlorosilane + water, acetyl chloride, permanganic acid,
ruthenium (VIII) oxide, uranyl perchlorate, potassium dioxide.
Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 64-17-5: KQ6300000
LD50/LC50:
CAS# 64-17-5:
Draize test, rabbit, eye: 500 mg Severe;
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, skin: 20 mg/24H Moderate;
Inhalation, mouse: LC50 = 39 gm/m3/4H;
Inhalation, rat: LC50 = 20000 ppm/10H;
Oral, mouse: LD50 = 3450 mg/kg;
Oral, rabbit: LD50 = 6300 mg/kg;
Oral, rat: LD50 = 7060 mg/kg;
Oral, rat: LD50 = 9000 mg/kg;
Carcinogenicity:
CAS# 64-17-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: Ethanol has been shown to produce fetotoxicity in the embry o or fetus
of laboratory animals. Prenatal exposure to ethanol is associated with a distinct pattern of
co ngenital malformations that have collecetively been termed the "fetal alcohol
syndrome".
Teratogenicity: Oral, Human - woman: TDLo = 41 gm/kg (female 41 week(s) after
conception) Effects on Newborn - Apgar score (human only) and Effects on Newborn other neonatal measures or effects and Effects on Newborn - drug dependence.
Reproductive Effects: Intrauterine, Human - woman: TDLo = 200 mg/kg (female 5 day
(s) pre-mating) Fertility - female fertility index (e.g. # females pregnant per # sperm
positive females; # females pregnant per # females mated).
Neurotoxicity: No information available.
Mutagenicity: DNA Inhibition: Human, Lymphocyte = 220 mmol/L.; Cytogenetic
Analysis: Human, Lymphocyte = 1160 gm/L.; Cytogenetic Analysis: Human, Fibroblast =
12000 ppm.; Cytogenetic Analysis: Human, Leukocyte = 1 pph/72H (Continuous).; Sister
Chromatid Exchange: Human, Lymphocyte = 500 ppm/72H (Continuous).
Other Studies: Standard Draize Test(Skin, rabbit) = 20 mg/24H (Moderate) S tandard
Draize Test: Administration into the eye (rabbit) = 500 mg (Severe).
Section 12 - Ecological Information
Ecotoxicity: Fish: Rainbow trout: LC50 = 12900-15300 mg/L; 96 Hr; Flow-through @
24-24.3°CFish: Rainbow trout: LC50 = 11200 mg/L; 24 Hr; Fingerling (Unspecified)
Bacteria: Phytobacterium phosphoreum: EC50 = 34900 mg/L; 5-30 min; Microtox test
When spilled on land it is apt to volatilize, biodegrade, and leach into the ground water,
but no data on the rates of these processes could be found. Its fate in ground water is
unknown. When released into water it will volatilize and probably biodegrade. It would
not be expected to adsorb to sediment or bioconcentrate in fish.
Environmental: When released to the atmosphere it will photodegrade in hours
(polluted urban atmosphere) to an estimated range of 4 to 6 days in less polluted areas.
Rainout should be significant.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
ETHANOL
Hazard Class: 3
UN Number:
Canada TDG
ETHANOL
3
UN1170
Packing Group: II
UN1170
II
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 64-17-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 64-17-5: acute, chronic, flammable.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 64-17-5 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
WARNING: This product contains Ethyl alcohol, a chemical known to the state of
California to cause birth defects or other reproductive harm. California No Significant Risk
Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
F
Risk Phrases:
R 11 Highly flammable.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 33 Take precautionary measures against static
discharges.
S 7 Keep container tightly closed.
S 9 Keep container in a well-ventilated place.
WGK (Water Danger/Protection)
CAS# 64-17-5: 0
Canada - DSL/NDSL
CAS# 64-17-5 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2A.
Canadian Ingredient Disclosure List
CAS# 64-17-5 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 64-17-5: OEL-AUSTRALIA:TWA 1000 ppm (1900 mg/m3) OEL-BELGIUM:T
WA 1000 ppm (1880 mg/m3) OEL-CZECHOSLOVAKIA:TWA 1000 mg/m3;STEL 5000
mg/m3 OEL-DENMARK:TWA 1000 ppm (1900 mg/m3) OEL-FINLAND:TWA 1000 ppm
(1900 mg/m3);STEL 1250 ppm (2400 mg/m3) OEL-FRANCE:TWA 1000 ppm (190
0 mg/m3);STEL 5000 pp OEL-GERMANY:TWA 1000 ppm (1900 mg/m3) OEL-HUNG
ARY:TWA 1000 mg/m3;STEL 3000 mg/m3 OEL-THE NETHERLANDS:TWA 1000 ppm (
1900 mg/m3) OEL-THE PHILIPPINES:TWA 1000 ppm (1900 mg/m3) OEL-POLAND
:TWA 1000 mg/m3 OEL-RUSSIA:STEL 1000 mg/m3 OEL-SWEDEN:TWA 1000 ppm (
1900 mg/m3) OEL-SWITZERLAND:TWA 1000 ppm (1900 mg/m3) OEL-THAILAND:T
WA 1000 ppm (1900 mg/m3) OEL-TURKEY:TWA 1000 ppm (1900 mg/m3) OEL-UN
ITED KINGDOM:TWA 1000 ppm (1900 mg/m3) JAN9 OEL IN BULGARIA, COLOMBIA
, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNA
M check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 10/24/2000
Revision #2 Date: 3/18/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Ethyl Alcohol, Denatured, 70% Solution
ACC# 88889
Section 1 - Chemical Product and Company Identification
MSDS Name: Ethyl Alcohol, Denatured, 70% Solution
Catalog Numbers: S71822
Synonyms: Ethanol Propdendary solvent 70% solution
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
64-17-5
7732-18-5
67-56-1
108-10-1
Chemical Name
Percent
EINECS/ELINCS
Ethyl alcohol
59.9
200-578-6
Water
34.9
231-791-2
Methyl alcohol
2.52
200-659-6
Methyl isobutyl ketone
1.33
203-550-1
Hazard Symbols: F
Risk Phrases: 11
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: clear, colorless liquid. Flash Point: 16.66 deg C. May cause central nervous
system depression. Flammable liquid and vapor. Cannot be made non-poisonous.
Causes severe eye irritation. Causes respiratory tract irritation. Causes moderate skin
irritation. This substance has caused adverse reproductive and fetal effects in humans.
Warning! May cause liver, kidney and heart damage.
Target Organs: Kidneys, heart, central nervous system, liver.
Potential Health Effects
Eye: Causes severe eye irritation. May cause painful sensitization to light. May cause
chemical conjunctivitis and corneal damage.
Skin: Causes moderate skin irritation. May be absorbed through the skin. May cause
cyanosis of the extremities.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May
cause systemic toxicity with acidosis. May cause central nervous system depression,
characterized by excitement, followed by headache, dizziness, drowsiness, and nausea.
Advanced stages may cause collapse, unconsciousness, coma and possible death due to
respiratory failure.
Inhalation: Inhalation of high concentrations may cause central nervous system effects
characterized by nausea, headache, dizziness, unconsciousness and coma. Causes
respiratory tract irritation. May cause narcotic effects in high concentration. Vapors may
cause dizziness or suffocation.
Chronic: May cause reproductive and fetal effects. Laboratory experiments have resulted
in mutagenic effects. Animal studies have reported the development of tumors. Prolonged
exposure may cause liver, kidney, and heart damage.
Section 4 - First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Call a poison control center. If swallowed, do not induce vomiting unless
directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively. Persons with skin or eye
disorders or liver, kidney, chronic respiratory diseases, or central and peripheral nervous
sytem diseases may be at increased risk from exposure to this substance.
Antidote: None reported.
Section 5 - Fire Fighting Measures
General Information: Containers can build up pressure if exposed to heat and/or fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/
NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive
mixture with air. Vapors can travel to a source of ignition and flash back. May burn with
invisible flame. Will burn if involved in a fire. Flammable Liquid. Can release vapors that
form explosive mixtures at temperatures above the flashpoint. Use water spray to keep
fire-exposed containers cool. Containers may explode if exposed to fire.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam.
Water may be ineffective. Do NOT use straight streams of water. Cool containers with
flooding quantities of water until well after fire is out.
Flash Point: 16.66 deg C ( 61.99 deg F)
Autoignition Temperature: 363 deg C ( 685.40 deg F)
Explosion Limits, Lower:3.3 vol %
Upper: 19.0 vol %
NFPA Rating: (estimated) Health: 1; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Avoid runoff into storm sewers and ditches which lead to
waterways. Clean up spills immediately, observing precautions in the Protective
Equipment section. Scoop up with a nonsparking tool, then place into a suitable container
for disposal. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A
vapor suppressing foam may be used to reduce vapors.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Use only in a well-ventilated area. Ground and bond containers when
transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact
with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or
vapor), and can be dangerous. Keep container tightly closed. Keep away from heat,
sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze,
solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Keep away from heat and flame.
Keep away from sources of ignition. Store in a tightly closed container. Keep from contact
with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible
substances. Flammables-area. Do not store near perchlorates, peroxides, chromic acid or
nitric acid.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility and a safety shower.
Use adequate general or local exhaust ventilation to keep airborne concentrations below
the permissible exposure limits.
Exposure Limits
Chemical Name
Ethyl alcohol
Water
ACGIH
1000 ppm TWA
none listed
Methyl alcohol
200 ppm TWA; 250
ppm STEL; skin potential for cutaneous
absorption
Methyl isobutyl ketone
50 ppm TWA; 75 ppm
STEL
NIOSH
OSHA - Final PELs
1000 ppm TWA; 1900
mg/m3 TWA 3300 ppm
IDLH
1000 ppm TWA; 1900
mg/m3 TWA
none listed
none listed
200 ppm TWA; 260 mg/ 200 ppm TWA; 260 mg/
m3 TWA 6000 ppm IDLH
m3 TWA
50 ppm TWA; 205 mg/
m3 TWA 500 ppm IDLH
100 ppm TWA; 410 mg/
m3 TWA
OSHA Vacated PELs: Ethyl alcohol: 1000 ppm TWA; 1900 mg/m3 TWA Water: No
OSHA Vacated PELs are listed for this chemical. Methyl alcohol: 200 ppm TWA; 260 mg/
m3 TWA Methyl isobutyl ketone: 50 ppm TWA; 205 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear, colorless
Odor: mild odor - characteristic odor
pH: Not available.
Vapor Pressure: 44.6 mm Hg @ 68 deg F
Vapor Density: 1.59 (air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 75-80 deg C
Freezing/Melting Point:-113 deg C
Decomposition Temperature:Not available.
Solubility: Miscible.
Specific Gravity/Density:0.8676 @ 20°C
Molecular Formula:Mixture
Molecular Weight:Not available.
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: High temperatures, incompatible materials, ignition sources,
excess heat, strong oxidants, oxidizers.
Incompatibilities with Other Materials: Strong oxidizing agents, acids, alkali metals,
ammonia, hydrazine, peroxides, sodium, acid anhydrides, calcium hypochlorite, chromyl
chloride, nitrosyl perchlorate, bromine pentafluoride, perchloric acid, silver nitrate,
mercuric nitrate, potassium-tert-butoxide, magnesium perchlorate, acid chlorides,
platinum, uranium hexafluoride, silver oxide, iodine heptafluoride, acetyl bromide,
disulfuryl difluoride, tetrachlorosilane + water, acetyl chloride, permanganic acid,
ruthenium (VIII) oxide, uranyl perchlorate, potassium dioxide.
Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide.
Hazardous Polymerization: Has not been reported
Section 11 - Toxicological Information
RTECS#:
CAS# 64-17-5: KQ6300000
CAS# 7732-18-5: ZC0110000
CAS# 67-56-1: PC1400000
CAS# 108-10-1: SA9275000
LD50/LC50:
CAS# 64-17-5:
Draize test, rabbit, eye: 500 mg Severe;
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, skin: 20 mg/24H Moderate;
Inhalation, mouse: LC50 = 39 gm/m3/4H;
Inhalation, rat: LC50 = 20000 ppm/10H;
Oral, mouse: LD50 = 3450 mg/kg;
Oral, rabbit: LD50 = 6300 mg/kg;
Oral, rat: LD50 = 7060 mg/kg;
Oral, rat: LD50 = 9000 mg/kg;
CAS# 7732-18-5:
Oral, rat: LD50 = >90 mL/kg;
CAS# 67-56-1:
Draize test, rabbit, eye: 40 mg Moderate;
Draize test, rabbit, eye: 100 mg/24H Moderate;
Draize test, rabbit, skin: 20 mg/24H Moderate;
Inhalation, rabbit: LC50 = 81000 mg/m3/14H;
Inhalation, rat: LC50 = 64000 ppm/4H;
Oral, mouse: LD50 = 7300 mg/kg;
Oral, rabbit: LD50 = 14200 mg/kg;
Oral, rat: LD50 = 5600 mg/kg;
Skin, rabbit: LD50 = 15800 mg/kg;
CAS# 108-10-1:
Draize test, rabbit, eye: 40 mg Severe;
Draize test, rabbit, eye: 100 uL/24H Moderate;
Draize test, rabbit, skin: 500 mg/24H Mild;
Inhalation, mouse: LC50 = 23300 mg/m3;
Inhalation, rat: LC50 = 100 gm/m3;
Oral, mouse: LD50 = 1900 mg/kg;
Oral, rat: LD50 = 2080 mg/kg;
Carcinogenicity:
CAS# 64-17-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 7732-18-5: Not
listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 67-56-1: Not listed by ACGIH, IARC,
NIOSH, NTP, or OSHA. CAS# 108-10-1: Not listed by ACGIH, IARC, NIOSH, NTP, or
OSHA.
Epidemiology: Ethanol has been shown to produce fetotoxicity in the embry o or fetus
of laboratory animals. Prenatal exposure to ethanol is associated with a distinct pattern of
co ngenital malformations that have collecetively been termed the "fetal alcohol
syndrome".
Teratogenicity: CAS# 64-17-5: Oral, Human - woman: TDLo = 41 gm/kg (female 41
week(s) after conception) Effects on Newborn - Apgar score (human only) and Effects on
Newborn - other neonatal measures or effects and Effects on Newborn - drug
dependence.
Reproductive Effects: CAS# 64-17-5: Intrauterine, Human - woman: TDLo = 200 mg/
kg (female 5 day(s) pre-mating) Fertility - female fertility index (e.g. # females pregnant
per # sperm positive females; # females pregnant per # females mated).
Neurotoxicity: No information available.
Mutagenicity: CAS# 64-17-5: DNA Inhibition: Human, Lymphocyte = 220 mmol/L.;
Cytogenetic Analysis: Human, Lymphocyte = 1160 gm/L.; Cytogenetic Analysis: Human,
Fibroblast = 12000 ppm.; Cytogenetic Analysis: Human, Leukocyte = 1 pph/72H
(Continuous).; Sister Chromatid Exchange: Human, Lymphocyte = 500 ppm/72H
(Continuous).
Other Studies: Standard Draize Test(Skin, rabbit) = 20 mg/24H (Moderate) S tandard
Draize Test: Administration into the eye (rabbit) = 500 mg (Severe).
Section 12 - Ecological Information
Ecotoxicity: Fish: Rainbow trout: LC50 = 12900-15300 mg/L; 96 Hr; Flow-through @
24-24.3°CFish: Rainbow trout: LC50 = 11200 mg/L; 24 Hr; Fingerling (Unspecified)
Bacteria: Phytobacterium phosphoreum: EC50 = 34900 mg/L; 5-30 min; Microtox test
CAS# 64-17-5: When spilled on land it is apt to volatilize, biodegrade, and leach into the
ground water, but no data on the rates of these processes could be found. Its fate in
ground water is unknown. When released into water it will volatilize and probably
biodegrade. It would not be expected to adsorb to sediment or bioconcentrate in fish.
Environmental: CAS# 64-17-5: When released to the atmosphere it will photodegrade
in hours (polluted urban atmosphere) to an estimated range of 4 to 6 days in less
polluted areas. Rainout should be significant.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 67-56-1: waste number U154 (Ignitable waste). CAS# 108-10-1:
waste number U161 (Ignitable waste).
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
ETHANOL
Hazard Class: 3
UN Number:
UN1170
Packing Group: II
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 64-17-5 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
CAS# 67-56-1 is listed on the TSCA inventory.
CAS# 108-10-1 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 108-10-1: Effective 10/4/82; Sunset 10/4/92
Chemical Test Rules
Canada TDG
No information
available.
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
CAS# 108-10-1: Present
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 67-56-1: 5000 lb final RQ; 2270 kg final RQ CAS# 108-10-1: 5000 lb final RQ;
2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 64-17-5: acute, chronic, flammable. CAS # 67-56-1: acute, flammable. CAS #
108-10-1: acute, chronic, flammable, reactive.
Section 313
This material contains Methyl alcohol (CAS# 67-56-1, 2 52%),which is subject to the
reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373. This
material contains Methyl isobutyl ketone (CAS# 108-10-1, 1 33%),which is subject to the
reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 67-56-1 is listed as a hazardous air pollutant (HAP). CAS# 108-10-1 is listed as a
hazardous air pollutant (HAP). This material does not contain any Class 1 Ozone
depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 64-17-5 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 67-56-1 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 108-10-1 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
WARNING: This product contains Ethyl alcohol, a chemical known to the state of
California to cause birth defects or other reproductive harm. California No Significant Risk
Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
F
Risk Phrases:
R 11 Highly flammable.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 33 Take precautionary measures against static
discharges.
S 7 Keep container tightly closed.
S 9 Keep container in a well-ventilated place.
WGK (Water Danger/Protection)
CAS# 64-17-5: 0
CAS# 7732-18-5: No information available.
CAS# 67-56-1: 1
CAS# 108-10-1: 1
Canada - DSL/NDSL
CAS# 64-17-5 is listed on Canada's DSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
CAS# 67-56-1 is listed on Canada's DSL List.
CAS# 108-10-1 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2A.
Canadian Ingredient Disclosure List
CAS# 64-17-5 is listed on the Canadian Ingredient Disclosure List.
CAS# 67-56-1 is listed on the Canadian Ingredient Disclosure List.
CAS# 108-10-1 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 64-17-5: OEL-AUSTRALIA:TWA 1000 ppm (1900 mg/m3) OEL-BELGIUM:T
WA 1000 ppm (1880 mg/m3) OEL-CZECHOSLOVAKIA:TWA 1000 mg/m3;STEL 5000
mg/m3 OEL-DENMARK:TWA 1000 ppm (1900 mg/m3) OEL-FINLAND:TWA 1000 ppm
(1900 mg/m3);STEL 1250 ppm (2400 mg/m3) OEL-FRANCE:TWA 1000 ppm (190
0 mg/m3);STEL 5000 pp OEL-GERMANY:TWA 1000 ppm (1900 mg/m3) OEL-HUNG
ARY:TWA 1000 mg/m3;STEL 3000 mg/m3 OEL-THE NETHERLANDS:TWA 1000 ppm (
1900 mg/m3) OEL-THE PHILIPPINES:TWA 1000 ppm (1900 mg/m3) OEL-POLAND
:TWA 1000 mg/m3 OEL-RUSSIA:STEL 1000 mg/m3 OEL-SWEDEN:TWA 1000 ppm (
1900 mg/m3) OEL-SWITZERLAND:TWA 1000 ppm (1900 mg/m3) OEL-THAILAND:T
WA 1000 ppm (1900 mg/m3) OEL-TURKEY:TWA 1000 ppm (1900 mg/m3) OEL-UN
ITED KINGDOM:TWA 1000 ppm (1900 mg/m3) JAN9 OEL IN BULGARIA, COLOMBIA
, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNA
M check ACGI TLV
CAS# 67-56-1: OEL-ARAB Republic of Egypt:TWA 200 ppm (260 mg/m3);Ski
n OEL-AUSTRALIA:TWA 200 ppm (260 mg/m3);STEL 250 ppm;Skin OEL-BELGIU
M:TWA 200 ppm (262 mg/m3);STEL 250 ppm;Skin OEL-CZECHOSLOVAKIA:TWA 10
0 mg/m3;STEL 500 mg/m3 OEL-DENMARK:TWA 200 ppm (260 mg/m3);Skin OELFINLAND:TWA 200 ppm (260 mg/m3);STEL 250 ppm;Skin OEL-FRANCE:TWA 200
ppm (260 mg/m3);STEL 1000 ppm (1300 mg/m3) OEL-GERMANY:TWA 200 ppm (2
60 mg/m3);Skin OEL-HUNGARY:TWA 50 mg/m3;STEL 100 mg/m3;Skin JAN9 OEL
-JAPAN:TWA 200 ppm (260 mg/m3);Skin OEL-THE NETHERLANDS:TWA 200 ppm (
260 mg/m3);Skin OEL-THE PHILIPPINES:TWA 200 ppm (260 mg/m3) OEL-POLA
ND:TWA 100 mg/m3 OEL-RUSSIA:TWA 200 ppm;STEL 5 mg/m3;Skin OEL-SWEDEN
:TWA 200 ppm (250 mg/m3);STEL 250 ppm (350 mg/m3);Skin OEL-SWITZERLAN
D:TWA 200 ppm (260 mg/m3);STEL 400 ppm;Skin OEL-THAILAND:TWA 200 ppm
(260 mg/m3) OEL-TURKEY:TWA 200 ppm (260 mg/m3) OEL-UNITED KINGDOM:TW
A 200 ppm (260 mg/m3);STEL 250 ppm;Skin OEL IN BULGARIA, COLOMBIA, JO
RDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM ch
eck ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 7/28/1999
Revision #3 Date: 12/03/2002
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
MATERIAL SAFETY DATA SHEET
GEBAUER COMPANY
4444 E 153rd St
CLEVELAND, OH 44128
1-800-321-9348 toll free or (216) 271-5252
FAX (216) 271-5335; WEBSITE: www.gebauerco.com
GEBAUER’S ETHYL CHLORIDE®
AFTER HOURS EMERGENCY: CHEMTREC (800) 424-9300
I. PRODUCT IDENTIFICATION
®
TRADE NAME
SYNONYM
GEBAUER’S ETHYL CHLORIDE
REVISION DATE March, 2004 By C. Kubat
CHEMICAL
NAME
SYNONYMS
ETHYL CHLORIDE, CHLOROETHANE, HYDROCHLORIC
ETHER
Chemical Family.
Halogenated Hydrocarbon
FORMULA
C2H5Cl
MOLECULAR WEIGHT
64.52
II. COMPOSITION/INFORMATION ON INGREDIENTS
Ingredient
CAS NO.
Concentration
OSHA PEL
ACGIH TLV-TWA
Ethyl Chloride
75-00-3
>99
1000ppm
100ppm
III. HAZARDS IDENTIFICATION
Health Rating
4 - Acute
Reactivity Rating
0 - None
Special Rating
Lab Protective Equipment
Storage Color Code
Inhalation
Ingestion
2 - Moderate
Flammability Rating
None
Neoprene or Viton gloves, labcoat, goggles or face shield, vent hood.
Red (Flammable)
Headache, dizziness, nausea, vomiting, loss of coordination and disorientation may produce narcotic and anesthetic effects. May produce central nervous
system depression, respiratory paralysis, or fatal coma with respiratory or cardiac arrest. May sensitize themyocardium to endogenous epinephrine, causing
dangerous dysrhythmias. Although absorbed through lungs and skin, it also is rapidly given off through the lungs.
Unlikely route of exposure due to gaseous nature.
Skin Contact
Rapid evaporation of liquid may cause frostbite. Symptoms of frostbite are blanching of the skin, cold feeling numbness. Cutaneous sensitization may
occur, but is extremely rare. Freezing can occasional alter pigmentation. A single prolonged skin exposure is not likely to result in absorption of harmful
amounts
Eye Contact
Is a slight irritant to mucosal tissues
Chronic Exposure
Aggravation of Preexisting
Conditions
Long term Exposure to high levels may produce the following: loss of muscle coordination, involuntary eye movements, tremors, speech disturbance,
sluggish reflexes and hallucinations. These symptoms are alleviated when the overexposure is ended.
The defatting properties of Ethyl Chloride may aggravate existing dermatitis.
IV. FIRST AID MEASURES
Inhalation
Ingestion
Immediately remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, qualified personnel may give oxygen. Call a physician.
Unlikely route of exposure due to gaseous nature.
Skin Contact
For exposure to liquid, immediately warm frostbite area with warm water not to exceed 105ºF (41ºC). In case of massive exposure, remove contaminated
clothing while showering with warm water. Call a physician.
Eye Contact
For contact with the liquid, immediately flush eyes thoroughly with warm water for at least 15 minutes. Hold the eyelids open and away from the eyeballs to
ensure that all surfaces are flushed thoroughly. See a physician, preferably an ophthalmologist, immediately.
V. FIRE FIGHTING MEASURES
Flash point - -58ºF (-50ºC) TCC, -45ºF (-43ºC) TOC
Autoignition temperature - 966ºF (519ºC)
FLAMMABLE LIMITS IN AIR (%by volume) - lower 3.8%
Upper 15.4%
Special Fire Fighting Procedures
DANGER! Flammable liquid and gas. Evacuate all personnel from danger area. Use water spray to cool fire-exposed containers, structures and equipment. Use water spray, carbon dioxide
or dry chemicals as extinguishing media. Remove sources of ignition if without risk. Remove all containers from fire area if without risk; continue cooling water spray while moving
containers. Do not extinguish any flames emitted from containers, stop flow of material if without risk, or allow flames to burn out. Self contained breathing apparatus may be required by
rescue workers.
Unusual Fire and Explosion Hazards
Flammable liquid and gas. Very dangerous fire hazard when exposed to heat, flame or powerful oxidizers. Ethyl chloride is heavier than air and the vapors may hug the ground, making
distant ignition and flashback possible. During a fire, toxic gases (hydrogen chloride, chlorine and phosgene) may be produced. Direct exposure to flames may cause container explosion.
Static discharge may ignite ethyl chloride.
VI. ACCIDENTAL RELEASE MEASURES
Spill and Leak Response
Flammable liquid and Gas. Eliminate all sources of ignition. Allow spilled ethyl chloride to evaporate, ventilate enclosed areas. In case of large spill, evacuate all personnel from area. For
Entry Into Unknown Concentrations That Could Be IDLH ( ≥ 3800 ppm ): Full Face Self Contained Breathing Apparatus
Waste Disposal Method
Comply with federal, state and local laws; return unused quantities to Gebauer co by making appropriate arrangements for pickup and transportation.
VII. HANDLING AND STORAGE
Storage Precautions
Store in cool, dry well ventilated area.. Protect against physical damage. Do not subject to temperatures above 120ºF (50ºC). Do not store near high frequency ultrasound equipment or nonexplosion proof electrical equipment.
Usage and Handling Precautions
Use in well-ventilated areas. Do not use near temperatures above 120ºF (50ºC). Do not use with cautery or non-explosion proof electrical equipment. Do not use near open flame.
VIII. EXPOSURE CONTROLS – PERSONAL PROTECTION
Ventilation/Engineering Controls
Use with adequate ventilation.
Skin Protection
For clinical setting: minimize inhalation of vapors by patient, especially when applying to head and neck. For large spills ( ≥ 1000 ppm twa and ≤ 3800 ppm
instantaneous exposure): full face, positive pressure , self-contained breathing apparatus should be available for emergency use.
Wear neoprene or viton gloves for exposures ≥1000 ppmTWA and ≤3800 ppm instantaneous exposure.
Eye Protection
Splash goggles or safety glasses.
Exposure Limits
OSHA – 1000ppm,
Respiratory Protection
PELACGLIH – 100 ppm TLV, A3
IDHL, – 3800 ppm LEL,
IX. PHYSICAL AND CHEMICAL PROPERTIES
Boiling Point
Freezing Point
Evaporation Rate (Butyl Acetate = 1)
Vapor Density (Air = 1 @ 70ºF))
Vapor Pressure (@ 68ºF)
54.1ºF (12.3ºC)
Specific Gravity (@ 68ºF)
-213.5ºF (-136.4ºC)
pH
Greater than 1
Solubility in Water
2.23
Essentially neutral
Slight by slow hydrolysis
Odor
20.1 psia (5.4 psig)
0.8939
Appearance
Ethereal
Clear and colorless liquid or gas
X. STABILITY AND REACTIVITY
Stability
Hazardous Decomposition
Products
Incompatible Materials
Normally stable in air. In presence of moisture, slowly hydrolyses forming hydrochloric acid.
Hazardous Polymerization
Not expected to occur.
Conditions to Avoid
Carbon monoxide, hydrogen chloride gas, phosgene gas, and carbon dioxide.
Alkali metals such as sodium, and potassium, powdered metals such as aluminum, zinc and magnesium and strong oxidizers.
Contact with incompatible materials and exposure to heat, sparks and other sources of ignition and exposure to high heat.
XI. TOXICOLOGICAL INFORMATION
Acute Inhalation LC50
Skin Irritation
Eye Irritation
Chronic Effects:
60,632 ppm (rat) (2 hr.) Anesthetic effects.
Produces frostbite.
Produces frostbite.
Is not listed as a carcinogen or suspected carcinogen by NTP or OSHA. Listed under IARC as a 3.
Effects of overexposure:
Acute:
Subchronic
Carcinogenicity:
Mutagenesis
Reproductive/Developmental:
Inhalation: Can produce varying degrees of intoxication; i.e. loss of coordination, drunkenness, possible convulsions, abdominal cramps, nausea and
coma. It has been reported that concentrated vapors can produce narcotic and anesthetic effects in humans and may produce deep or even fatal
anesthesia. Inhalation may also be irritating to the respiratory tract.
Eye/Skin: Liquid spilled on skin may cause possible frostbite. For eye contact, there are no specific known effects., but the effects may be the same as
contact with skin.
Increased liver weights were observed in rats and mice after exposure to 2500, 5000, 10,000 and 19,000 ppm for 6 hrs/day, 5 dys/week for 13 weeks. No
other effects were observed in the study.
Carcinomas of the uterus were observed in female mice exposed to 15,000 pppm during the course of a 2-year inhalation study.
Has been shown to be mutagenic in bacteria, with and without activation. A 2-year study in mice did not yield increases in bone marrow micronuclei.
No teratogenic effects were observed in mice exposed to 500, 1500 or 5000 ppm during organogenesis . No effects on reproductive organs were
observed after 13 weeks exposure to vapors.
XII. ECOLOGICAL INFORMATION
Environmental Stability
Gas is dissipated rapidly in a ventilated area.
Effect on Plants and Animals
Suspected to have toxic effects with long term exposure to: central nervous system depression, liver and kidney. No information on adverse effects to plant
life., except for frost produced upon evaporation.
Effect on Aquatic Life
No evidence currently available.
XIII. DISPOSAL CONSIDERATIONS
Waste disposal must be in accordance with appropriate Federal, State and local regulations.
XIV. TRANSPORT INFORMATION
Proper Shipping Name
Hazard Class
Identification Number
Packing Group
Reportable Quantity
DOT Label(s) Required
Canada TDG Description
Ethyl Chloride
2.1 (Flammable Gas)
UN 1037
I (49 CFR 173.322)
100 LBS./45.4 Kg
Flammable Gas
Ethyl Chloride, Class 2.1, UN1037 **Special Commodity**
XV. REGULATORY INFORMATION
USA TSCA:
Listed
Canada DSL:
Listed
Korea ECL:
Listed
Europe EINECS:
Listed
Australia AICS:
Listed
Japan MITI (ENCS):
Listed
SARA Title III
Section 302: not listed. Sections 311, 312: acute health hazard. Section 313: listed.
CERCLA
Listed with a reportable quantity of 100 lbs.
State Regulatory Information:
Ethyl Chloride is covered under
The specific State regulations listed.
California Proposition 65:
Alaska
California
Florida
Illinois
Massachusetts
Michigan
Minnesota
Missouri
New Jersey
Rhode Island
Texas
West Virginia
Wisconsin
Designated Toxic and Hazardous Substances
Permissible Exposure Limits for Chemical Contaminants
Substance List
Toxic Substance List
Substance List
Critical Materials Register
List of Hazardous Substances
Employer Information/Toxic Substance List
Right to Know Hazardous Substance List
Hazardous Substance
Hazardous Substance List
Hazardous Substance List
Toxic and Hazardous Substances
CANADA Regulations (WHMIS):
Class A – Compressed Gas
Class B1 – Flammable Gas
Class D2A – Other Toxic Effects
EUROPEAN UNION CLASSIFICATION:
Hazard Symbol: F+;Xn
Risk Phrases: R12-40-52/53
Safety Phrases: S(2-) 9-16-33-36/37-61
Ethyl Chloride is on the California Proposition 65 lists. This product contains a chemical known to the State of California to cause cancer.
XVI. OTHER INFORMATOIN
This MSDS was revised and updated as of 11/25/02 by Gebauer Company.
INFORMATION CONTAINED IN THIS MATERIAL SAFETY DATA SHEET IS OFFERED WITHOUT CHARGE FOR USE BY TECHNICALLY QUALIFIED PERSONNEL AT THEIR DISCRETION AND RISK. ALL STATEMENTS, TECHNICAL INFORMATION AND
RECOMMENDATIONS CONTAINED HEREIN ARE BASED ON TESTS AND DATA WHICH WE BELIEVE TO BE RELIABLE, BUT THE ACCURACY OR COMPLETENESS THEREOF IS NOT GUARANTEED AND NO WARRANTY OF ANY KIND IS MADE WITH
RESPECT THERETO. THIS INFORMATION IS NOT INTENDED AS A LICENSE TO OPERATE UNDER OR A RECOMMENDATION TO PRACTICE OR INFRINGE ANY PATENT OF THIS COMPANY OR OTHER COVERING ANY PROCESS, COMPOSITION OF
MATTER OR USE. SINCE THE COMPANY SHALL HAVE NO CONTROL OF THE USE OF THE PRODUCT DESCRIBED HEREIN, THE COMPANY ASSUMES NO LIABILITY OF LOSS OR DAMAGE INCURRED FROM THE PROPER OR IMPROPER USE OF SUCH
PRODUCT.
Material Safety Data Sheet
Ethyl ether
ACC# 90868
Section 1 - Chemical Product and Company Identification
MSDS Name: Ethyl ether
Catalog Numbers: AC326860000, AC326860010, AC326861000, AC326862500,
AC364330000, AC364330010, AC364331000, AC610600190, AC610600500,
AC610601150, AC610602000, AC610800190, AC610800500, AC610801150,
AC610802000, AC615070040, AC615080010, AC615080040, AC615080200,
AC615085000, S73990, S73990ACS-1, S73990ACS-2, S73990ANES-1, S73990ANES-2,
E134-1, E134-20, E134-4, E136-150, E137POP19, E137POP200, E137POP50, E137RS19, E137RS-200, E137RS-50, E137SS19, E137SS200, E137SS50, E138-1, E138-20,
E138-4, E138-500, E1381U, E138ALC, E138J4, E138POP19, E138RS19, E138RS50,
E138SS19, E188-20, E188-4, E188-500, E197-1, E197-4, E1974U, E198-4, E198J4,
E198RS19, E199-4, E492-20, E492-4, E49220LC, NC9118371, S17573MF, S73990-1,
S73990-2, S73990SPEC
Synonyms: Ethane, 1,1'-oxybis-; Anesthetic ether; Diethyl ether; Ethoxyethane; Diethyl
oxide; Ethyl ether; Ether; Ethyl oxide.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
60-29-7
Chemical Name
Ethyl ether
Percent
EINECS/ELINCS
>99
200-467-2
Hazard Symbols: XN F+
Risk Phrases: 12 19 22
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: APHA: 10 max clear liquid. Flash Point: -45 deg C. Danger! May form
explosive peroxides. Hygroscopic (absorbs moisture from the air). Air sensitive. Light
sensitive. Aspiration hazard if swallowed. Can enter lungs and cause damage. May be
harmful if swallowed. May be habit forming. Extremely flammable liquid and vapor. Vapor
may cause flash fire. This material has been reported to be susceptible to autoxidation
and therefore should be classified as peroxidizable. Breathing vapors may cause
drowsiness and dizziness. Repeated exposure may cause skin dryness or cracking.
Causes eye irritation.
Target Organs: Central nervous system, respiratory system, eyes, skin.
Potential Health Effects
Eye: Causes moderate eye irritation. Causes redness and pain.
Skin: Causes skin irritation. May be absorbed through the skin. Repeated or prolonged
exposure may cause drying and cracking of the skin.
Ingestion: Aspiration hazard. Symptoms may include: headache, excitement, fatigue,
nausea, vomiting, stupor, and coma. May cause central nervous system depression,
characterized by excitement, followed by headache, dizziness, drowsiness, and nausea.
Advanced stages may cause collapse, unconsciousness, coma and possible death due to
respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis,
which may be fatal.
Inhalation: Exposure to high concentrations may produce narcosis, nausea and loss of
consciousness. Inhalation of vapors may cause drowsiness and dizziness.
Chronic: Prolonged or repeated skin contact may cause defatting and dermatitis.
Prolonged or repeated exposure can cause psychic abnormalities such as anxiety,
depression and excitability. Laboratory experiments have resulted in mutagenic effects.
Prolonged exposure to high vapor concentrations may cause eye injury. Repeated
exposures may be habit forming. Prolonged or repeated inhalation or ingestion may
result in liver and kidney changes.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid.
Skin: In case of contact, immediately flush skin with plenty of water. Remove
contaminated clothing and shoes. Get medical aid. Wash clothing before reuse.
Ingestion: Potential for aspiration if swallowed. Get medical aid immediately. Do not
induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Persons with kidney disease, chronic respiratory disease, liver
disease, or skin disease may be at increased risk from exposure to this substance.
Alcoholic beverage consumption may enhance the toxic effects of this substance. Treat
symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Vapors may form an explosive mixture with air. Extremely flammable. Material will
readily ignite at room temperature. Use water spray to keep fire-exposed containers cool.
Water may be ineffective. Material is lighter than water and a fire may be spread by the
use of water. Containers may explode in the heat of a fire. May form explosive peroxides.
Will be easily ignited by heat, sparks or flame. May re-ignite after fire is extinguished.
Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors
can spread along the ground and collect in low or confined areas. This liquid floats on
water and may travel to a source of ignition and spread fire.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. Water may be ineffective. For large fires, use water spray, fog or
alcohol-resistant foam. Do NOT use straight streams of water. Cool containers with
flooding quantities of water until well after fire is out.
Flash Point: -45 deg C ( -49.00 deg F)
Autoignition Temperature: 180-190 deg C
Explosion Limits, Lower:1.9 vol %
Upper: 36.0 vol %
NFPA Rating: (estimated) Health: 1; Flammability: 4; Instability: 1
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Avoid runoff into storm sewers and ditches which lead to
waterways. Remove all sources of ignition. Use a spark-proof tool. Place under an inert
atmosphere. A vapor suppressing foam may be used to reduce vapors.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Ground and bond containers when transferring material. Avoid contact with
eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor),
and can be dangerous. Take precautionary measures against static discharges. Keep
container tightly closed. Keep away from heat, sparks and flame. Handle under an inert
atmosphere. If peroxide formation is suspected, do not open or move container. Do not
pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat,
sparks or open flames. Use only with adequate ventilation. Avoid breathing vapor.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition.
Do not store near combustible materials. Do not store in direct sunlight. Store in a tightly
closed container. Store in a cool, dry, well-ventilated area away from incompatible
substances. Flammables-area. Do not expose to air. Store protected from light. Store
under an inert atmosphere. Keep away from oxidizing agents. Containers should be dated
when opened and tested periodically for the presence of peroxides. Should crystals form
in a peroxidizable liquid, peroxidation may have occurred and the product should be
considered extremely dangerous. In this instance, the container should only be opened
remotely by professionals. Store at room temperature or below. Do not exceed 86°F. Do
not open unless contents are at 72°F or below for at least 24 hours. Ethyl ether may form
explosive peroxides on long standing or after exposure to air or light. All peroxidizable
substances should be stored away from heat and light and be protected from ignition
sources.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use process enclosure, local exhaust ventilation, or other
engineering controls to control airborne levels below recommended exposure limits. Use
explosion-proof ventilation equipment. Facilities storing or utilizing this material should
be equipped with an eyewash facility and a safety shower.
Exposure Limits
Chemical Name
Ethyl ether
ACGIH
400 ppm TWA; 500
ppm STEL
NIOSH
OSHA - Final PELs
1900 ppm IDLH
400 ppm TWA; 1200
mg/m3 TWA
OSHA Vacated PELs: Ethyl ether: 400 ppm TWA; 1200 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Clear liquid
Appearance: APHA: 10 max
Odor: sweetish odor - aromatic odor
pH: Not available.
Vapor Pressure: 442 mm Hg @ 20 deg C
Vapor Density: 2.55 (Air=1)
Evaporation Rate:37.5 (Butyl acetate=1)
Viscosity: 0.2448 cp @20 deg C
Boiling Point: 34.6 deg C
Freezing/Melting Point:-116.3 deg C
Decomposition Temperature:Not available.
Solubility: Slightly soluble.
Specific Gravity/Density:<.7079 g/ml
Molecular Formula:C4H10O
Molecular Weight:74.12
Section 10 - Stability and Reactivity
Chemical Stability: Under normal storage conditions, peroxidizable compounds can
form and accumulate peroxides which may explode when subjected to heat or shock. This
material is most hazardous when peroxide levels are concentrated by distillation or
evaporation.
Conditions to Avoid: Light, ignition sources, exposure to air, electrical sparks, exposure
to flame, heat.
Incompatibilities with Other Materials: Strong oxidizing agents, strong acids.
Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide, peroxides.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 60-29-7: KI5775000
LD50/LC50:
CAS# 60-29-7:
Draize test, rabbit, eye: 100 mg Moderate;
Inhalation, mouse: LC50 = 31000 ppm/30M;
Oral, rat: LD50 = 1215 mg/kg;
Skin, rabbit: LD50 = >20 mL/kg;
Carcinogenicity:
CAS# 60-29-7: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: DNA Repair: Escherichia coli = 35670 ug/well/16H.; DNA Inhibition:
Mouse, Embryo = 2850 mg/L.; Mutation Test Systems - not otherwise specified:
Hamster, Fibroblast = 1 pph.
Other Studies: Open Irritation Test: Administration onto the skin (rabbit) = 360 mg
(Mild). Standard Draize Test: Administration into the eye (rabbit) = 100 mg (Moderate).
Standard Draize Test : Administration onto the skin (rabbit) = 50 mg/24H (Sev ere).
Standard Draize Test: Administration into the eye (human) = 100 ppm.
Section 12 - Ecological Information
Ecotoxicity: Fish: Fathead Minnow: LC50 = 2600 mg/L; 96 Hr; Flow-through
bioassayFish: Bluegill/Sunfish: LC50 >10000 mg/L; 96 Hr; Static bioassayBacteria:
Phytobacterium phosphoreum: EC50 = 5625 mg/L; 15 min; Microtox test If ethyl ether is
released to soil, it will be subject to volatilization. It will be expected to exhibit high
mobility in soil and, therefore, it may leach to groundwater. If ethyl ether is released to
water, it will not be expected to significantly adsorb to sediment or suspended particulate
matter, bioconcentrate in aquatic organisms or hydrolyze.
Environmental: Ethyl ether will not significantly photooxidize via reaction with
photochemically produced hydroxyl radicals in the water. Ethyl ether in surface water will
be subject to rapid volatilization with estimated half-lives of 3.1 hr and 1.5 days. It will
not be expected to hydrolyze in water or soil. If ethyl ether is released to the
atmosphere, it will be expected to exist almost entirely in the vapor phase.It will be
susceptible to photooxidation via vapor phase reaction with photochemically produced
hydroxyl radicals with a half-life of 29 hours.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 60-29-7: waste number U117 (Ignitable waste).
Section 14 - Transport Information
US DOT
Shipping
Name:
DIETHYL
ETHER
Hazard Class: 3
IATA
RID/ADR
IMO
Canada TDG
DIETHYL ETHER
3
UN Number:
UN1155
Packing Group: I
UN1155
I
Additional
Info:
FLASHPOINT -40
C
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 60-29-7 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 60-29-7: 100 lb final RQ; 45.4 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 60-29-7: acute, flammable, sudden release of pressure, reactive.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 60-29-7 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN F+
Risk Phrases:
R 12 Extremely flammable.
R 19 May form explosive peroxides.
R 22 Harmful if swallowed.
R 66 Repeated exposure may cause skin dryness or
cracking.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 29 Do not empty into drains.
S 33 Take precautionary measures against static
discharges.
S 9 Keep container in a well-ventilated place.
WGK (Water Danger/Protection)
CAS# 60-29-7: 1
Canada - DSL/NDSL
CAS# 60-29-7 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2.
Canadian Ingredient Disclosure List
CAS# 60-29-7 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 60-29-7: OEL-AUSTRALIA:TWA 400 ppm (1200 mg/m3);STEL 500 ppm (1
500 mg/m3) OEL-AUSTRIA:TWA 400 ppm (1200 mg/m3) OEL-BELGIUM:TWA 400
ppm (1210 mg/m3);STEL 500 ppm (1520 mg/m3) OEL-CZECHOSLOVAKIA:TWA 500
mg/m3;STEL 1500 mg/m3 OEL-DENMARK:TWA 400 ppm (1200 mg/m3) OEL-FINL
AND:TWA 400 ppm (1200 mg/m3);STEL 500 ppm (1500 mg/m3) OEL-FRANCE:TWA
400 ppm (1200 mg/m3);STEL 500 ppm (1500 mg/m3) OEL-GERMANY:TWA 400 p
pm (1200 mg/m3) OEL-HUNGARY:TWA 300 mg/m3;STEL 600 mg/m3;Skin OEL-JA
PAN:TWA 400 ppm (1200 mg/m3) OEL-THE NETHERLANDS:TWA 400 ppm (1200 mg
/m3) JAN9 OEL-THE PHILIPPINES:TWA 400 ppm (1200 mg/m3) JAN9 OEL-POLA
ND:TWA 300 mg/m3 OEL-RUSSIA:TWA 400 ppm;STEL 300 mg/m3 OEL-SWEDEN:TW
A 400 ppm (1200 mg/m3);STEL 500 ppm (1500 mg/m3) OEL-SWITZERLAND:TWA
400 ppm (1200 mg/m3);STEL 800 ppm OEL-TURKEY:TWA 400 ppm (1200 mg/m3)
OEL-UNITED KINGDOM:TWA 400 ppm (1200 mg/m3);STEL 500 ppm OEL IN BUL
GARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SI
NGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 6/02/1999
Revision #6 Date: 5/05/2004
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Ethylenediamine Tetraacetic Acid, Disodium Salt, Dihydrate
ACC# 08308
Section 1 - Chemical Product and Company Identification
MSDS Name: Ethylenediamine Tetraacetic Acid, Disodium Salt, Dihydrate
Catalog Numbers: BP120-1, BP120-500, NC9058584, O2793-500, S311-10, S311-100,
S311-3, S311-500, S311-50KG, S311-50LB, S312-12, S312-125LB, S312-212, S312500, S316-12, S316-212, S76761, XXS311ET500GM
Synonyms: Disodium EDTA dihydrate; EDTA disodium dihydrate; Disodium edetate.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
6381-92-6
Chemical Name
Disodium ethylenediaminetetraacetate
dihydrate
Percent
EINECS/ELINCS
100
unlisted
Hazard Symbols: XN
Risk Phrases: 22 36/37/38
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: white crystalline powder. Causes eye and skin irritation. May be harmful if
swallowed. Warning! Causes respiratory tract irritation.
Target Organs: Eyes, skin.
Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation.
Ingestion: Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May be
harmful if swallowed.
Inhalation: Causes respiratory tract irritation.
Chronic: No information found.
Section 4 - First Aid Measures
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the
upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or
other symptoms appear.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion.
Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 1; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Avoid generating dusty conditions. Provide ventilation.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust
generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container
tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.
Storage: Store in a cool, dry, well-ventilated area away from incompatible substances.
Keep containers tightly closed.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits
Chemical Name
ACGIH
NIOSH
OSHA - Final PELs
Disodium ethylenediaminetetraacetate
dihydrate
none listed
none listed
none listed
Disodium ethylenediaminetetraacetate
anhydrous
none listed
none listed
none listed
OSHA Vacated PELs: Disodium ethylenediaminetetraacetate dihydrate: No OSHA
Vacated PELs are listed for this chemical. Disodium ethylenediaminetetraacetate
anhydrous: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Crystalline powder
Appearance: white
Odor: none reported
pH: 5.3 @ aqueous sol.
Vapor Pressure: Not applicable.
Vapor Density: Not available.
Evaporation Rate:Not applicable.
Viscosity: Not applicable.
Boiling Point: Decomposes
Freezing/Melting Point:252 deg C (decomposes)
Decomposition Temperature:> 252 deg C
Solubility: Soluble in water
Specific Gravity/Density:Not available.
Molecular Formula:C10H14N2Na2O8 2H2O
Molecular Weight:372.23
Section 10 - Stability and Reactivity
Chemical Stability: Stable at room temperature in closed containers under normal
storage and handling conditions.
Conditions to Avoid: Dust generation, excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, irritating and
toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 6381-92-6: AH4410000
CAS# 139-33-3: AH4375000
LD50/LC50:
Not available.
CAS# 139-33-3:
Oral, mouse: LD50 = 2050 mg/kg;
Oral, rabbit: LD50 = 2300 mg/kg;
Oral, rat: LD50 = 2 gm/kg;
Carcinogenicity:
CAS# 6381-92-6: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 139-33-3:
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: See actual entry in RTECS for complete information.
Section 12 - Ecological Information
No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
No
information
available.
Canada TDG
No information
available.
Hazard Class:
UN Number:
Packing Group:
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 6381-92-6 is not on the TSCA Inventory because it is a hydrate. It is considered to
be listed if the CAS number for the anhydrous form is on the inventory (40CFR720.3(u)
(2)).
CAS# 139-33-3 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 6381-92-6: acute.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 6381-92-6 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 139-33-3 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 22 Harmful if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 6381-92-6: 2
CAS# 139-33-3: 2
Canada - DSL/NDSL
CAS# 6381-92-6 is listed on Canada's DSL List.
CAS# 139-33-3 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D2B.
Canadian Ingredient Disclosure List
Exposure Limits
Section 16 - Additional Information
MSDS Creation Date: 2/23/1999
Revision #3 Date: 3/04/2004
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
MSDS Number: F1360 * * * * * Effective Date: 08/10/04 * * * * * Supercedes: 11/02/01
FERRIC SUBSULFATE SOLUTION
1. Product Identification
Synonyms: Ferric sulphate, basic, solution; iron hydroxide sulfate; Monsel's solution
CAS No.: 1310-45-8
Molecular Weight: 737.7
Chemical Formula: Fe4(OH)2(SO4)5 (approx.) solution
Product Codes:
J.T. Baker: 2041
Mallinckrodt: 5548, 6430
2. Composition/Information on Ingredients
Ingredient
Hazardous
-----------------------------------------------
CAS No
Percent
------------
------------
Ferric Subsulfate
Yes
Water
No
1310-45-8
40 - 70%
7732-18-5
30 - 60%
3. Hazards Identification
Emergency Overview
-------------------------CAUTION! MAY BE HARMFUL IF SWALLOWED. MAY CAUSE IRRITATION TO SKIN, EYES,
AND RESPIRATORY TRACT.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
----------------------------------------------------------------------------------------------------------Health Rating: 1 - Slight
Flammability Rating: 0 - None
Reactivity Rating: 0 - None
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES
Storage Color Code: Orange (General Storage)
----------------------------------------------------------------------------------------------------------Potential Health Effects
---------------------------------Although little information is available in the literature, it is expected that the health hazards for iron
compounds reflect those for this material.
Inhalation:
May cause irritation to the respiratory tract.
Ingestion:
Low toxicity in small quantities but larger dosages may cause nausea, vomiting, diarrhea, and black stool. Pink
urine discoloration is a strong indicator of iron poisoning. Liver damage, coma, and death from iron poisoning
has been reported.
Skin Contact:
No adverse effects expected.
Eye Contact:
Splashes may cause irritation.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or eye problems, or impaired liver, kidney or respiratory function may
be more susceptible to the effects of the substance.
4. First Aid Measures
Inhalation:
Remove to fresh air. Get medical attention for any breathing difficulty.
Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an
unconscious person.
Skin Contact:
Wash exposed area with soap and water. Get medical advice if irritation develops.
Eye Contact:
Wash thoroughly with running water. Get medical advice if irritation develops.
5. Fire Fighting Measures
Fire:
Not considered to be a fire hazard.
Explosion:
Not considered to be an explosion hazard.
Fire Extinguishing Media:
Use any means suitable for extinguishing surrounding fire.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus
with full facepiece operated in the pressure demand or other positive pressure mode.
6. Accidental Release Measures
Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills:
Pick up and place in a suitable container for reclamation or disposal, using a method that does not generate dust.
7. Handling and Storage
Store in a tightly closed container. Protect against physical damage, direct sunlight, and freezing. Containers of
this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all
warnings and precautions listed for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
-ACGIH Threshold Limit Value (TLV):
1 mg/m3 (TWA) soluble iron salt as Fe
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne
Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the
contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH
document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible, a half facepiece particulate respirator
(NIOSH type N95 or better filters) may be worn for up to ten times the exposure limit or the maximum use
concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest.. A fullface piece particulate respirator (NIOSH type N100 filters) may be worn up to 50 times the exposure limit, or
the maximum use concentration specified by the appropriate regulatory agency, or respirator supplier,
whichever is lowest. If oil particles (e.g. lubricants, cutting fluids, glycerine, etc.) are present, use a NIOSH
type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-facepiece
positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in
oxygen-deficient atmospheres.
Skin Protection:
Wear protective gloves and clean body-covering clothing.
Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
Reddish-brown liquid.
Odor:
Nearly odorless.
Solubility:
Miscible in water.
Specific Gravity:
ca. 1.54
pH:
Acidic to litmus.
% Volatiles by volume @ 21C (70F):
No information found.
Boiling Point:
Decomposes.
Melting Point:
No information found.
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
10. Stability and Reactivity
Stability:
Freezes at cool temperatures. Light sensitive.
Hazardous Decomposition Products:
Oxides of sulfur and the contained metal.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
No incompatibility data found.
Conditions to Avoid:
Light and low temperatures.
11. Toxicological Information
No LD50/LC50 information found relating to normal routes of occupational exposure.
--------\Cancer Lists\--------------------------------------------------------NTP Carcinogen--Ingredient
Known
Anticipated
IARC Category
-------------------------------------------------------------Ferric Subsulfate (1310-45-8)
No
No
None
Water (7732-18-5)
No
No
None
12. Ecological Information
Environmental Fate:
No information found.
Environmental Toxicity:
No information found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste
disposal facility. Processing, use or contamination of this product may change the waste management options.
State and local disposal regulations may differ from federal disposal regulations. Dispose of container and
unused contents in accordance with federal, state and local requirements.
14. Transport Information
Not regulated.
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\--------------------------------Ingredient
TSCA EC
Japan Australia
----------------------------------------------- ---- --- ----- --------Ferric Subsulfate (1310-45-8)
Yes Yes
No
Yes
Water (7732-18-5)
Yes Yes
Yes
Yes
--------\Chemical Inventory Status - Part 2\----------------------------------Canada-Ingredient
Korea DSL
NDSL Phil.
----------------------------------------------- ----- ------ ----Ferric Subsulfate (1310-45-8)
Yes
Yes
No
No
Water (7732-18-5)
Yes
Yes
No
Yes
--------\Federal, State & International Regulations - Part 1\----------------SARA 302------SARA 313-----Ingredient
RQ
TPQ
List Chemical Catg.
----------------------------------------- ---------- -------------Ferric Subsulfate (1310-45-8)
No
No
No
No
Water (7732-18-5)
No
No
No
No
--------\Federal, State & International Regulations - Part 2\----------------RCRA-TSCAIngredient
CERCLA
261.33
8(d)
----------------------------------------- ---------------Ferric Subsulfate (1310-45-8)
No
No
No
Water (7732-18-5)
No
No
No
Chemical Weapons Convention: No
TSCA 12(b): No
SARA 311/312: Acute: Yes
Chronic: No
Fire: No
Reactivity: No
(Mixture / Liquid)
CDTA: No
Pressure: No
Australian Hazchem Code: None allocated.
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR)
and the MSDS contains all of the information required by the CPR.
16. Other Information
NFPA Ratings: Health: 1 Flammability: 0 Reactivity: 0
Label Hazard Warning:
CAUTION! MAY BE HARMFUL IF SWALLOWED. MAY CAUSE IRRITATION TO SKIN, EYES, AND
RESPIRATORY TRACT.
Label Precautions:
Avoid contact with eyes, skin and clothing.
Keep container closed.
Use with adequate ventilation.
Wash thoroughly after handling.
INTENDED FOR FDA APPROVED USE ONLY.
NOT ON THE TSCA INVENTORY.
Label First Aid:
If swallowed, induce vomiting immediately as directed by medical personnel. Never give anything by mouth to
an unconscious person. If inhaled, remove to fresh air. Get medical attention for any breathing difficulty. In
case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes.
Product Use:
For Food and Drug or Research and Development use
Revision Information:
No Changes.
Disclaimer:
************************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no
representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the
appropriate precautionary handling of the material by a properly trained person using this product.
Individuals receiving the information must exercise their independent judgment in determining its
appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO
REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING
WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR
THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT
BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR
RELIANCE UPON THIS INFORMATION.
************************************************************************************************
Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)
Material Safety Data Sheet
Formaldehyde Solution 37%
ACC# 50002
Section 1 - Chemical Product and Company Identification
MSDS Name: Formaldehyde Solution 37%
Catalog Numbers: S74337MF, S74338MF, BF79-4LC, BP530-25, BP530-500, BP531-25,
BP531-500, F75F-1GAL, F75P-20, F75P-4, F75P1GAL, F77-20, F77-200, F77P-20, F77P4, F79-1, F79-20, F79-200, F79-4, F79-4LC, F79-500, F79J-1, F79J-4, F79P-20, F79P-4,
NC9527860
Synonyms: None.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
Percent
EINECS/ELINCS
Water
48
231-791-2
50-00-0
Formaldehyde
37
200-001-8
67-56-1
Methyl alcohol
15
200-659-6
0.0-1.1
unlisted
7732-18-5
Not avail.
Chemical Name
Odor mask
Hazard Symbols: T C
Risk Phrases: 10 23/24/25 34 40 43
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless liquid. Flash Point: 50 deg C. May cause central nervous system
depression. This substance has caused adverse reproductive and fetal effects in animals.
May cause liver and kidney damage. Cannot be made non-poisonous. Potential cancer
hazard. Contains formaldehyde. Flammable liquid and vapor. Danger! May be fatal or
cause blindness if swallowed. Vapor harmful. May cause allergic skin and respiratory
reaction. Causes eye, skin, and respiratory tract irritation.
Target Organs: Kidneys, central nervous system, liver, skin.
Potential Health Effects
Eye: Causes eye irritation. May cause chemical conjunctivitis and corneal damage.
Skin: Causes skin irritation. May cause skin sensitization, an allergic reaction, which
becomes evident upon re-exposure to this material. May cause cyanosis of the
extremities.
Ingestion: May be fatal or cause blindness if swallowed. Causes gastrointestinal
irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May
cause central nervous system depression, characterized by excitement, followed by
headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse,
unconsciousness, coma and possible death due to respiratory failure. May cause central
nervous system depression.
Inhalation: Inhalation of high concentrations may cause central nervous system effects
characterized by nausea, headache, dizziness, unconsciousness and coma. Causes
respiratory tract irritation. May cause asthmatic attacks due to allergic sensitization of the
respiratory tract. Aspiration may lead to pulmonary edema. Vapors may cause dizziness
or suffocation. May cause burning sensation in the chest.
Chronic: Repeated exposure may cause skin discoloration and thickening and nail decay.
Repeated inhalation is associated with nasal and nasopharyngeal cancer.
Section 4 - First Aid Measures
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the
upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub eyes or
keep eyes closed.
Skin: Immediately flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash
clothing before reuse. Destroy contaminated shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. Get medical aid
immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air
immediately. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water
runoff can cause environmental damage. Dike and collect water used to fight fire. Vapors
may form an explosive mixture with air. Vapors can travel to a source of ignition and
flash back. Will burn if involved in a fire. Use water spray to keep fire-exposed containers
cool. Containers may explode in the heat of a fire. Flammable liquid and vapor.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam.
Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use
straight streams of water.
Flash Point: 50 deg C ( 122.00 deg F)
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 2; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Avoid runoff into storm sewers and ditches which lead to
waterways. Clean up spills immediately, observing precautions in the Protective
Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide
ventilation. A vapor suppressing foam may be used to reduce vapors.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Use only in a well-ventilated area. Ground and bond containers when
transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact
with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or
vapor), and can be dangerous. Keep container tightly closed. Keep away from heat,
sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze,
solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition.
Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. Keep containers tightly closed.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible exposure limits. See
29CFR 1910.1048 for regulatory requirements pertaining to all occupational exposures to
formaldehyde, i.e., from formaldehyde gas, its solutions, and materials that release
formaldehyde.
Exposure Limits
Chemical Name
Water
ACGIH
none listed
NIOSH
OSHA - Final PELs
none listed
none listed
Formaldehyde
0.3 ppm Ceiling
0.75 ppm TWA; 2 ppm
STEL; 0.5 ppm Action
0.016 ppm TWA 20 ppm
Level (Irritant and
IDLH
potential cancer ha zard
- see 29 CFR 1910.1048)
Methyl alcohol
200 ppm TWA; 250
ppm STEL; skin potential for cutaneous
absorption
200 ppm TWA; 260 mg/ 200 ppm TWA; 260 mg/
m3 TWA 6000 ppm IDLH
m3 TWA
Odor mask
none listed
none listed
none listed
OSHA Vacated PELs: Water: No OSHA Vacated PELs are listed for this chemical.
Formaldehyde: 3 ppm TWA (unless specified in 1910.1048) Methyl alcohol: 200 ppm
TWA; 260 mg/m3 TWA Odor mask: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or
European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved
respirator when necessary.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: colorless
Odor: pungent odor
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: >1.0
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 101 deg C
Freezing/Melting Point:32 deg F
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:Not available.
Molecular Formula:Mixture
Molecular Weight:Not available
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, ignition sources, excess heat, oxidizers.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, oxides of phosphorus,
irritating and toxic fumes and gases, carbon dioxide, toxic fumes of sodium oxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 7732-18-5: ZC0110000
CAS# 50-00-0: LP8925000
CAS# 67-56-1: PC1400000
CAS# Not avail. unlisted.
LD50/LC50:
CAS# 7732-18-5:
Oral, rat: LD50 = >90 mL/kg;
CAS# 50-00-0:
Draize test, rabbit, eye: 750 ug/24H Severe;
Draize test, rabbit, eye: 750 ug Severe;
Draize test, rabbit, eye: 10 mg Severe;
Draize test, rabbit, eye: 37% Severe;
Draize test, rabbit, skin: 2 mg/24H Severe;
Draize test, rabbit, skin: 50 mg/24H Moderate;
Inhalation, mouse: LC50 = 454 gm/m3/4H;
Inhalation, mouse: LC50 = 505 mg/m3/2H;
Inhalation, rat: LC50 = 203 mg/m3;
Inhalation, rat: LC50 = 578 mg/m3/2H;
Inhalation, rat: LC50 = 250 ppm/2H;
Oral, mouse: LD50 = 42 mg/kg;
Oral, mouse: LD50 = 385 mg/kg;
Oral, mouse: LD50 = 500 mg/kg;
Oral, rat: LD50 = 100 mg/kg;
Oral, rat: LD50 = 500 mg/kg;
Skin, rabbit: LD50 = 270 uL/kg;
Skin, rabbit: LD50 = 270 mg/kg;
CAS# 67-56-1:
Draize test, rabbit, eye: 40 mg Moderate;
Draize test, rabbit, eye: 100 mg/24H Moderate;
Draize test, rabbit, skin: 20 mg/24H Moderate;
Inhalation, rabbit: LC50 = 81000 mg/m3/14H;
Inhalation, rat: LC50 = 64000 ppm/4H;
Oral, mouse: LD50 = 7300 mg/kg;
Oral, rabbit: LD50 = 14200 mg/kg;
Oral, rat: LD50 = 5600 mg/kg;
Skin, rabbit: LD50 = 15800 mg/kg;
Carcinogenicity:
CAS# 7732-18-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 50-00-0:
ACGIH: A2 - Suspected Human Carcinogen
California: carcinogen, initial date 1/1/88 (gas)
NIOSH: potential occupational carcinogen
NTP: Suspect carcinogen
OSHA: Possible Select carcinogen
IARC: Group 2A carcinogen CAS# 67-56-1: Not listed by ACGIH, IARC, NIOSH, NTP, or
OSHA. CAS# Not avail.: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No data available.
Teratogenicity: No data available.
Reproductive Effects: No data available.
Neurotoxicity: No data available.
Mutagenicity: No data available.
Other Studies: No data available.
Section 12 - Ecological Information
No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 50-00-0: waste number U122. CAS# 67-56-1: waste number
U154 (Ignitable waste).
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
FORMALDEHYDE,
SOLUTIONS,
FLAMMABLE
Hazard Class: 3
UN Number:
Packing
Group:
Canada TDG
FORMALDEHYDE,
SOLUTIONS,
FLAMMABLE
3
UN1198
III
UN1198
III
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 7732-18-5 is listed on the TSCA inventory.
CAS# 50-00-0 is listed on the TSCA inventory.
CAS# 67-56-1 is listed on the TSCA inventory.
Odor mask is not listed on the TSCA inventory. It is for research and development use
only.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 50-00-0: 100 lb final RQ; 45.4 kg final RQ CAS# 67-56-1: 5000 lb final RQ; 2270
kg final RQ
SARA Section 302 Extremely Hazardous Substances
CAS# 50-00-0: 500 lb TPQ
SARA Codes
CAS # 50-00-0: acute, chronic. CAS # 67-56-1: acute, flammable.
Section 313
This material contains Formaldehyde (CAS# 50-00-0, 37%),which is subject to the
reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373. This
material contains Methyl alcohol (CAS# 67-56-1, 15%),which is subject to the reporting
requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 50-00-0 is listed as a hazardous air pollutant (HAP). CAS# 67-56-1 is listed as a
hazardous air pollutant (HAP). This material does not contain any Class 1 Ozone
depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 50-00-0 is listed as a Hazardous Substance under the CWA. None of the chemicals
in this product are listed as Priority Pollutants under the CWA. None of the chemicals in
this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 50-00-0 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 67-56-1 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# Not avail. is not present on state lists from CA, PA, MN, MA, FL, or NJ.
WARNING: This product contains Formaldehyde, a chemical known to the state of
California to cause cancer. California No Significant Risk Level: CAS# 50-00-0: 40 æg/
day NSRL
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
TC
Risk Phrases:
R 10 Flammable.
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 34 Causes burns.
R 40 Limited evidence of a carcinogenic effect.
R 43 May cause sensitization by skin contact.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 51 Use only in well-ventilated areas.
WGK (Water Danger/Protection)
CAS# 7732-18-5: No information available.
CAS# 50-00-0: 2
CAS# 67-56-1: 1
CAS# Not avail.: No information available.
Canada - DSL/NDSL
CAS# 7732-18-5 is listed on Canada's DSL List.
CAS# 50-00-0 is listed on Canada's DSL List.
CAS# 67-56-1 is listed on Canada's DSL List.
Canada - WHMIS
This product does not have a WHMIS classification.
Canadian Ingredient Disclosure List
CAS# 50-00-0 is listed on the Canadian Ingredient Disclosure List.
CAS# 67-56-1 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 50-00-0: OEL-ARAB Republic of Egypt:TWA 2 ppm (3 mg/m3) OEL-AU
STRALIA:TWA 1 ppm (1.5 mg/m3);STEL 2 ppm (3 mg/m3);CAR OEL-BELGIUM:TW
A 1 ppm (1.2 mg/m3);STEL 2 ppm (2.5 mg/m3);CAR OEL-CZECHOSLOVAKIA:TWA
0.5 mg/m3;STEL 1 mg/m3 OEL-DENMARK:STEL 0.3 ppm (0.4 mg/m3);Carcinog
en OEL-FINLAND:STEL 1 ppm (1.3 mg/m3);Skin OEL-FRANCE:STEL 2 ppm (3
mg/m3) OEL-GERMANY:TWA 0.5 ppm (0.6 mg/m3);Carcinogen OEL-HUNGARY:ST
EL 0.6 mg/m3;Carcinogen OEL-JAPAN:TWA 0.5 ppm (0.61 mg/m3);Carcinogen
OEL-THE NETHERLANDS:TWA 1 ppm (1.5 mg/m3);STEL 2 ppm (3 mg/m3) OELTHE PHILIPPINES:TWA 5 ppm (6 mg/m3) OEL-POLAND:TWA 2 mg/m3 OEL-RUSSI
A:TWA 0.5 ppm;STEL 0.5 mg/m3;Skin OEL-SWEDEN:TWA 0.5 ppm (0.6 mg/m3);
STEL 1 ppm (1. mg/m3) OEL-SWITZERLAND:TWA 0.5 ppm (0.6 mg/m3);STEL 1
pp (1.2 mg/m3) OEL-THAILAND:TWA 3 ppm;STEL 5 ppm OEL-TURKEY:TWA 5 pp
m (6 mg/m3) OEL-UNITED KINGDOM:TWA 2 ppm (2.5 mg/m3);STEL 2 ppm (2.5
mg/m3) OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL
IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
CAS# 67-56-1: OEL-ARAB Republic of Egypt:TWA 200 ppm (260 mg/m3);Ski
n OEL-AUSTRALIA:TWA 200 ppm (260 mg/m3);STEL 250 ppm;Skin OEL-BELGIU
M:TWA 200 ppm (262 mg/m3);STEL 250 ppm;Skin OEL-CZECHOSLOVAKIA:TWA 10
0 mg/m3;STEL 500 mg/m3 OEL-DENMARK:TWA 200 ppm (260 mg/m3);Skin OELFINLAND:TWA 200 ppm (260 mg/m3);STEL 250 ppm;Skin OEL-FRANCE:TWA 200
ppm (260 mg/m3);STEL 1000 ppm (1300 mg/m3) OEL-GERMANY:TWA 200 ppm (2
60 mg/m3);Skin OEL-HUNGARY:TWA 50 mg/m3;STEL 100 mg/m3;Skin JAN9 OEL
-JAPAN:TWA 200 ppm (260 mg/m3);Skin OEL-THE NETHERLANDS:TWA 200 ppm (
260 mg/m3);Skin OEL-THE PHILIPPINES:TWA 200 ppm (260 mg/m3) OEL-POLA
ND:TWA 100 mg/m3 OEL-RUSSIA:TWA 200 ppm;STEL 5 mg/m3;Skin OEL-SWEDEN
:TWA 200 ppm (250 mg/m3);STEL 250 ppm (350 mg/m3);Skin OEL-SWITZERLAN
D:TWA 200 ppm (260 mg/m3);STEL 400 ppm;Skin OEL-THAILAND:TWA 200 ppm
(260 mg/m3) OEL-TURKEY:TWA 200 ppm (260 mg/m3) OEL-UNITED KINGDOM:TW
A 200 ppm (260 mg/m3);STEL 250 ppm;Skin OEL IN BULGARIA, COLOMBIA, JO
RDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM ch
eck ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 7/12/1999
Revision #8 Date: 2/24/2004
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Page 1 of 6
@
Beckman
Coulter
MATERIAL SAFETY DATA SHEET
TM
Section 1 Company and Product Identification
Product Name
GastroccultDeveloper
Part Number
66115
Series Name
66000 Series
Manufacturer
Beckman Coulter, Inc.
4300 Harbor Blvd.
Fullerton, CA 92834-3100, U.S.A.
Distributor and
Emergency Phone No.
☎
Doc. ID 66115-75 AB
Issued (year/month/day)
Revised (year/month/day) 2003/03/07
Refer to attached list, Document ID: 472050, for local distributor and
emergency phone numbers.
Section 2 Composition and Information on Ingredients
Hazardous Ingredients:
Meets Hazardous Criteria:
Chemical Name
CAS #
% by wt.
7722-84-1
<5%
77-92-9
octylphenoxypoly(ethoxyethanol)
Ethanol-methanol mix
Hydrogen Peroxide
Citric Acid
EU
US OSHA
WHMIS
No
Yes
Exempt
<5%
No
Yes
Exempt
9036-19-5
<5%
No
Yes
Exempt
8013-52-3
<50%
Yes
Exempt
F;R11
Xn;R20/21/2268/20/21/22
See Section 15 Regulatory Information for additional information on hazard classifications.
Section 3 Hazards Identification
Emergency Overview
Colorless;
Clear;
Liquid; Alcohol odor
Flammable liquid and vapor.
CNS depressant. Eye, skin and respiratory tract irritant.
Physical Hazards
Vapors of flammable ingredients are heavier than air and may travel to an ignition
source, ignite and flash back.
Potential Health
Effects Summary
May cause eye, skin and respiratory tract irritation and central nervous system
depression with headache, dizziness, nausea and unconsciousness.
See Section 11 Toxicological Information for more detailed health information.
Product Hazard
Classifications
EU:
Xn;R10-20/21/2268/20/21/22
WHMIS:
Exempt
2003 Beckman Coulter, Inc.
Global MSDS – English
US OSHA:
Hazardous
GastroccultDeveloper
MSDS # 66115-75 AB
Page 2 of 6
Section 3 Hazards Identification (Continued)
Beckman Coulter Safety
Rating
Flammability (Section V): 2
Health (Section XI): 2
Reactivity with Water (Section X): 2
Contact (Section VIII): 2
Code
0=none
1=slight
2=caution
3=severe
Section 4 First Aid Measures
Inhalation
If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artificial respiration immediately and obtain medical attention.
Eye Contact
If product enters eyes, wash eyes gently under running water for 15 minutes or
longer, making sure that the eyelids are held open. If pain or irritation occur, obtain
medical attention.
Skin Contact
In case of skin contact, flush with copious amounts of water for at least 15 minutes. If
pain or irritation occur, obtain medical attention.
Ingestion
If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical
attention.
Section 5 Fire Fighting Measures
Flash Point
21°C(69.8°F)
Flammable Limits
Lower flammable limit: 3.3%; Upper flammable limit: 19%
Autoignition Temp.
Not available
Extinguishing Media
Dry chemical, carbon dioxide, regular foam or water spray.
Special Fire and
Explosion Hazards
Vapors form explosive mixtures with air. Vapors are heavier than air; fire may flash
from ignition source back along vapor trail.
Hazardous Combustion
Products
Depending upon fire conditions, combustion products may range from irritants and
asphyxiants to acutely toxic gases.
Protective Equipment
for Firefighters
Self-contained breathing apparatus is recommended for firefighters.
Section 6 Accidental Release Measures
Personal Precautions
Use good laboratory procedures; avoid eye and skin contact.
Spill and Leak
Procedures
Absorb spilled material with an appropriate inert, non-flammable absorbent and
dispose according to local regulations.
Environmental
Precautions
Contain spill to prevent migration.
Section 7 Handling and Storage
Handling Precautions
Use in well ventilated area away from heat or ignition sources.
Use good laboratory procedures; avoid eye and skin contact.
Recommended Storage
Conditions
To maintain efficacy, store according to the instructions in the product labeling.
GastroccultDeveloper
MSDS # 66115-75 AB
Page 3 of 6
Section 8 Exposure Controls and Personal Protection
Exposure Limits
US OSHA:
Hydrogen Peroxide
1 ppm TWA; 1.4 mg/m3 TWA
ACGIH:
Hydrogen Peroxide
1 ppm TWA
DFG MAK:
Hydrogen Peroxide
1 ppm MAK; 1.4 mg/m3 MAK; 1 ppm Peak; 1.4 mg/m3 Peak
Engineering Controls
No special engineering controls are required. Use with good general ventilation.
Respiratory Protection
Under normal conditions, the use of this product should not require respiratory
protection. If overexposure should occur and ventilation is not adequate to maintain
airborne concentrations at acceptable levels, the use of respiratory protection should
be evaluated by a qualified professional.
Eye Protection
Safety glasses or chemical goggles should be worn to prevent eye contact.
Skin Protection
Impervious gloves, such as latex or equivalent, should be worn to prevent skin
contact.
Section 9 Physical and Chemical Properties
Physical State
Liquid
Color
Colorless
Transparency
Clear
Odor
Alcohol odor
Odor Threshold
Not applicable
pH
5-5.5
Boiling Point
<100°C(212°F)
Melting Point
Not available
Specific Gravity
0.90 @20°C
Vapor Pressure
18 mm Hg @19°C
Vapor Density
1.6 (air=1)
Evaporation Rate
Not available
Solubility
Water
Miscible
Organic
Not available
Section 10 Stability and Reactivity
Stability
Stable under normal temperatures and pressures.
GastroccultDeveloper
MSDS # 66115-75 AB
Page 4 of 6
Section 10 Stability and Reactivity (Continued)
Hazardous
Incompatibilities
Halogens
Strong bases
Strong oxidizers
Strong acids
Hazardous
Decomposition Products
When stored as labeled, no known hazardous decomposition products are formed
during the shelf-life of this product.
Conditions to Avoid
Avoid contact with heat, ignition sources and incompatible materials.
Section 11 Toxicological Information
Toxicity Data
for Hazardous Ingredients
Citric Acid
Hydrogen Peroxide
Oral LD50 Rat: 3 gm/kg; Oral LD50 Mouse: 5040 mg/kg
Oral LD50 Rat: 1518 mg/kg
Oral LD50 Rat: 4190 mg/kg; Oral LD50 Mouse: 3500 mg/kg
octylphenoxypoly(ethoxyethanol)
Primary Routes
The most likely routes of exposure are skin and eye contact. Inhalation may occur if
of Exposure
mists are formed in product use.
Potential Effects of
Acute Exposure
May cause irritation or burning of skin and eyes by contact. Inhalation and ingestion
of large volumes may cause burning of mucous membrane, respiratory irritation, and
central nervous system depression.
Potential Effects of
Chronic Exposure
Chronic exposure may result in effects similar to those described for acute exposure.
Frequent or long-term contact may dry out the skin resulting in dermatitis.
Symptoms of
Overexposure
Symptoms of overexposure may include: throat irritation and coughing; dry, red,
cracked skin; red irritated eyes; headache, drowsiness, dizziness, stupor; convulsions
and coma.
Carcinogenicity
This product does not contain a reportable concentration (≥ 0.1%) of any ingredient
listed as carcinogen by ACGIH, IARC, NTP, OSHA or 67/548/EEC Annex I.
Other Effects
None identified.
Conditions Aggravated
by Exposure
Individuals with eye and skin disorders may find these conditions aggravated by
exposure to this product.
Individuals with eye, kidney, liver and cardiovascular, nervous and respiratory system
disorders may find these conditions aggravated by exposure to this product.
Section 12 Ecological Information
Ecotoxicity
Toxic to fish and other water organisms.
Biodegradability
No information available.
Mobility
No information available.
Section 13 Disposal Considerations
Waste Disposal
Dispose of waste product, unused product and contaminated packaging in compliance
with federal, state and local regulations. If unsure of the applicable requirements,
contact the authorities for information.
GastroccultDeveloper
MSDS # 66115-75 AB
Page 5 of 6
Section 14 Transport Information
International Shipping
Information
Shipping Name
CONSUMER COMMODITY
ICAO UN/ID Number
8000
IATA Packing Group
II
IATA
Hazard Class
9 Miscellaneous Dangerous Goods
Subsidiary Risk
None
Special Provisions
A112
IMDG Hazard Class
US DOT
European ADR
Canadian TDG
Subsidiary Risk
9 Miscellaneous dangerous
substances and articles
None
Special Provisions
None
Marine Pollutant
No
Hazard Class
ORM-D
Subsidiary Risk
None
Special Provisions
None
ADR Classification
Subsidiary Risk
9Miscellaneous dangerous
substances and articles
None
Item Number and Letter
None
PIN
8000
TDG Classification
9 Miscellaneous Dangerous Goods
Subsidiary Risk
None
Special Provisions
None
Section 15 Regulatory Information
US Federal and State Regulations
SARA 313
CERCLA RG’s,
40 CFR 302.4
California Proposition 65
Ethylene Oxide is subject to reporting requirements of Section 313, Title III of SARA.
1,4-Dioxane is subject to reporting requirements of Section 313, Title III of SARA.
Ethylene Oxide is listed.
1,4-Dioxane is listed.
Ethylene Oxide has been identified by the State of California to cause cancer and
reproductive harm. The State of California has adopted a regulation which requires a
warning be given to individuals who may be exposed to chemicals identified by the State
to cause cancer or reproductive harm. Accordingly, Beckman Coulter advises you of the
following warning:
WARNING: This product contains a chemical known to the State of California to cause
cancer and reproductive harm.
1,4-Dioxane has been identified by the State of California to cause cancer. The State of
California has adopted a regulation which requires a warning be given to individuals who
may be exposed to chemicals identified by the State to cause cancer or reproductive
harm. Accordingly, Beckman Coulter advises you of the following warning:
WARNING: This product contains a chemical known to the State of California to cause
cancer.
GastroccultDeveloper
MSDS # 66115-75 AB
Page 6 of 6
Section 15 Regulatory Information (Continued)
US Federal and State Regulations
Massachusetts MSL
Ethylene Oxide is listed.
1,4-Dioxane is listed.
Hydrogen Peroxide is listed.
New Jersey Dept. of
Health RTK List
Ethylene Oxide is listed.
1,4-Dioxane is listed.
Hydrogen Peroxide is listed.
Pennsylvania RTK
Ethylene Oxide is listed.
1,4-Dioxane is listed.
Hydrogen Peroxide is listed.
Florida Substance List
Ethylene Oxide is listed.
1,4-Dioxane is listed.
Hydrogen Peroxide is listed.
EU Labeling Classification
Classification
Risk and Safety Phrases
Xn
R10 Flammable.
R20/21/22 Harmful by inhalation, in contact with skin and if swallowed.
Harmful
R68/20/21/22 Harmful: possible risk of irreversible effects through inhalation, in
contact with skin and if swallowed.
S16
Keep away from sources of ignition—No smoking.
Canada
This product is exempt from WHMIS label and MSDS requirements.
PIN:
8000
Ingredients on Ingredient
Disclosure List:
Ethylene Oxide
Citric Acid
1,4-Dioxane
Hydrogen Peroxide
octylphenoxypoly(ethoxyethanol)
Ingredients with unknown
toxicological properties:
Product is exempt
Section 16 Other Information
For further information, please contact your local Beckman Coulter representative.
WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR
REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE
OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.
Material Safety Data Sheet
Gentian Violet
ACC# 10350
Section 1 - Chemical Product and Company Identification
MSDS Name: Gentian Violet
Catalog Numbers: A4213197, C581-100, C581-25, G12-100, NC9611056, SG201GALD, SG20-250D, XXC5812KG
Synonyms: Aniline violet; Crystal violet; Hexamethyl pararosaniline chloride.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
548-62-9
Chemical Name
C.I. BASIC VIOLET 1
Percent
EINECS/ELINCS
~100.0
208-953-6
Hazard Symbols: XN
Risk Phrases: 22 41
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: green solid. May cause severe eye irritation and possible injury. May cause
skin irritation. May cause respiratory and digestive tract irritation. May cause
reproductive and fetal effects. Warning! Harmful if swallowed.
Target Organs: None known.
Potential Health Effects
Eye: May cause severe eye irritation. This product contains a cationic dye. Similar dyes
have caused permanent injury to the cornea and conjunctiva in documented exposure
cases with human or rabbit eyes.
Skin: May cause skin irritation.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation: May cause respiratory tract irritation.
Chronic: No information found.
Section 4 - First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid immediately.
Skin: Immediately flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give
anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts
at sufficient concentrations can form explosive mixtures with air. Combustion generates
toxic fumes.
Extinguishing Media: For small fires, use water spray, dry chemical, carbon dioxide or
chemical foam.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Sweep up, then place into a suitable container for disposal. Avoid
generating dusty conditions.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Use with adequate ventilation. Minimize dust generation and accumulation.
May form flammable dust-air mixtures. Avoid contact with skin and eyes. Keep container
tightly closed. Avoid ingestion and inhalation.
Storage: Do not store in direct sunlight. Store in a cool, dry, well-ventilated area away
from incompatible substances.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name
C.I. BASIC VIOLET 1
ACGIH
none listed
NIOSH
OSHA - Final PELs
none listed
none listed
OSHA Vacated PELs: C.I. BASIC VIOLET 1: No OSHA Vacated PELs are listed for this
chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or
European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved
respirator when necessary.
Section 9 - Physical and Chemical Properties
Physical State: Solid
Appearance: green
Odor: none reported
pH: Not available.
Vapor Pressure: Negligible.
Vapor Density: Not applicable.
Evaporation Rate:Negligible.
Viscosity: Not available.
Boiling Point: Not applicable.
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: Soluble in water.
Specific Gravity/Density:Not available.
Molecular Formula:C25H30ClN3
Molecular Weight:407.6831
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures. Materials
containing similar functional groups can decompose at elevated temperatures.
Conditions to Avoid: Incompatible materials, dust generation.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon
monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 548-62-9: BO9000000
LD50/LC50:
CAS# 548-62-9:
Oral, mouse: LD50 = 96 mg/kg;
Oral, rabbit: LD50 = 150 mg/kg;
Oral, rat: LD50 = 420 mg/kg;
Carcinogenicity:
CAS# 548-62-9: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: Embryo or Fetus: Stunted fetus, oral-rabbit TDLo=7mg/kg.Specific
Developmental Abnormalities: Musculoskeletal, oral-rat TDLo=100mg/kg.
Reproductive Effects: Fertility: Post-implantation mortality, oral-rat TDLo=40mg/kg.
Neurotoxicity: No information available.
Mutagenicity: Please refer to RTECS# BO9000000 for specific informaton.
Other Studies: None.
Section 12 - Ecological Information
Ecotoxicity: No data available. No information available.
Environmental: No information reported.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
No
information
available.
Hazard Class:
UN Number:
Packing Group:
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 548-62-9 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
Canada TDG
No information
available.
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 548-62-9: acute.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 548-62-9 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 22 Harmful if swallowed.
R 41 Risk of serious damage to eyes.
Safety Phrases:
S 22 Do not breathe dust.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
WGK (Water Danger/Protection)
CAS# 548-62-9: 2
Canada - DSL/NDSL
CAS# 548-62-9 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D1B, D2B.
Canadian Ingredient Disclosure List
CAS# 548-62-9 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
Section 16 - Additional Information
MSDS Creation Date: 11/11/1997
Revision #2 Date: 3/18/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Glycerin
ACC# 10440
Section 1 - Chemical Product and Company Identification
MSDS Name: Glycerin
Catalog Numbers: S71228, S71229, S74606, S74606-1, S746061, BP229-1, BP229-4,
G153-1, G153-4, G30-20, G30-200, G30-4, G31-1, G31-20, G31-4, G31-500, G33-1,
G33-20, G33-200, G33-4, G33-500, G334LC, G34-20, G34-200, G34-4, G36-20, G37-20,
G37-200, G37-4, NC9117583, NC9484773, XXBP22920LI
Synonyms: Glycerol; 1,2,3-Propanetriol; Glycyl alcohol; 1,2,3-Trihydroxypropane;
Glycerine.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
56-81-5
Chemical Name
Glycerin
Percent
EINECS/ELINCS
100.0
200-289-5
Hazard Symbols: None listed.
Risk Phrases: None listed.
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: clear liquid. Caution! This is expected to be a low hazard for usual
industrial handling. May cause eye, skin, and respiratory tract irritation.
Target Organs: None known.
Potential Health Effects
Eye: May cause eye irritation.
Skin: May cause skin irritation. Low hazard for usual industrial handling.
Ingestion: Ingestion of large amounts may cause gastrointestinal irritation. Low hazard
for usual industrial handling. May cause headache.
Inhalation: Low hazard for usual industrial handling. Inhalation of a mist of this material
may cause respiratory tract irritation.
Chronic: No information found.
Section 4 - First Aid Measures
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the
upper and lower eyelids. If irritation develops, get medical aid.
Skin: Flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash
clothing before reuse.
Ingestion: Never give anything by mouth to an unconscious person. Do NOT induce
vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Get
medical aid if irritation or symptoms occur.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or
other symptoms appear.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Use water spray to keep fire-exposed containers cool.
Vapors may be heavier than air. They can spread along the ground and collect in low or
confined areas. Containers may explode when heated.
Extinguishing Media: Use water spray to cool fire-exposed containers. Use agent most
appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or
appropriate foam.
Flash Point: 193 deg C ( 379.40 deg F)
Autoignition Temperature: 400 deg C ( 752.00 deg F)
Explosion Limits, Lower:1.1
Upper: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 1; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Avoid runoff into storm sewers and ditches which lead to
waterways. Clean up spills immediately, observing precautions in the Protective
Equipment section. Remove all sources of ignition. Provide ventilation.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Wash hands before eating. Use with
adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly
closed. Avoid ingestion and inhalation. Wash clothing before reuse.
Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area
away from incompatible substances. No special precautions indicated.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits
Chemical Name
Glycerin
ACGIH
10 mg/m3 TWA
NIOSH
OSHA - Final PELs
none listed
15 mg/m3 TWA (total
dust); 5 mg/m3 TWA
(respirable fraction)
OSHA Vacated PELs: Glycerin: 10 mg/m3 TWA (total dust); 5 mg/m3 TWA (respirable
fraction)
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or
European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved
respirator when necessary.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear
Odor: faint odor
pH: Not available.
Vapor Pressure: .0025 mm Hg @ 5
Vapor Density: 3.17 (H2O=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 290 deg C
Freezing/Melting Point:20 deg F
Decomposition Temperature:290 deg C
Solubility: Miscible in water. Insol. in chloroform,
Specific Gravity/Density:1.2610g/cm3 @ 20°C
Molecular Formula:C3H8O3
Molecular Weight:92.0542
Section 10 - Stability and Reactivity
Chemical Stability: Stable.
Conditions to Avoid: Incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials: Acetic anhydride, potassium permanganate,
strong acids, caustics (e.g. ammonia, ammonium hydroxide, calcium hydroxide,
potassium hydroxide, sodium hydroxide), isocyanates, oxidizing agents, aliphatic amines.
Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 56-81-5: MA8050000
LD50/LC50:
CAS# 56-81-5:
Draize test, rabbit, eye: 126 mg Mild;
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, skin: 500 mg/24H Mild;
Inhalation, rat: LC50 = >570 mg/m3/1H;
Oral, mouse: LD50 = 4090 mg/kg;
Oral, rabbit: LD50 = 27 gm/kg;
Oral, rat: LD50 = 12600 mg/kg;
Skin, rabbit: LD50 = >10 gm/kg;
Carcinogenicity:
CAS# 56-81-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: No data available.
Section 12 - Ecological Information
Ecotoxicity: No data available. Cas# 56-81-5:LC50 (96 Hr.) rainbow trout = 50-67 mg/
L; 12 degrees CLC50 (96 Hr.) goldfish = >5000 mg/L
Environmental: No information available.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
No
information
available.
Hazard Class:
UN Number:
Packing Group:
Section 15 - Regulatory Information
Canada TDG
No information
available.
US FEDERAL
TSCA
CAS# 56-81-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 56-81-5: chronic.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 56-81-5 can be found on the following state right to know lists: Pennsylvania,
Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 56-81-5: 0
Canada - DSL/NDSL
CAS# 56-81-5 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of Not controlled..
Canadian Ingredient Disclosure List
Exposure Limits
CAS# 56-81-5: OEL-AUSTRALIA:TWA 10 mg/m3 OEL-BELGIUM:TWA 10 mg/m3
OEL-FINLAND:TWA 20 mg/m3 OEL-FRANCE:TWA 10 mg/m3 OEL-THE NETHERLANDS
:TWA 10 mg/m3 OEL-UNITED KINGDOM:TWA 10 mg/m3 OEL IN BULGARIA, COLOM
BIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIE
TNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 7/20/1999
Revision #4 Date: 2/20/2002
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Hexane
ACC# 10951
Section 1 - Chemical Product and Company Identification
MSDS Name: Hexane
Catalog Numbers: S80032, S800321, S800322MF, BPH292RS-115, BPH292RS-200,
BPH292RS-28, BPH292RS-50, H291-20, H291-200, H291-4, H291-500, H291FB-115,
H291FB-19, H291FB-200, H291FB-50, H291POP-19, H291POP-200, H291POP-50,
H291POPB-19, H291POPB-200, H291POPB-50, H291RS-19, H291S-4, H291SS-115,
H291SS-19, H291SS-200, H291SS-28, H291SS-50, H292-1, H292-20, H292-200, H2924, H292-500, H292FB-115, H292FB-19, H292FB-200, H292FB-50, H292J-4, H292POP19,
H292POP200, H292POP50, H292POPB19, H292POPB200, H292POPB50, H292RB-115,
H292RB-19, H292RB-200, H292RB-50, H292RS-19, H292RS115, H292RS200,
H292RS28, H292RS50, H292SK-4, H292SS-115, H292SS-200, H292SS-28, H292SS-50,
H292SS1350, H292SS19, H302-1, H302-4, H302-4LC, H302J-1, H302J-4, H302N-119,
H302N-219, H302NB-219, H302POP-19, H302POP-200, H302POP-50, H302POPN-19,
H302RS-115, H302RS-19, H302RS-200, H302RS-28, H302RS-50, H302SK-1, H302SK-4,
H302SS-115, H302SS-19, H302SS-200, H302SS-28, H302SS-50, H303-1, H303-4, H3034LC, H3034LOT010, H3034LOT011, H3034LOT015, H3034LOT023, H3034LOT024, H303J1, H303J-4, H303POP-19, H303POP-200, H303POP-50, H303RS-115, H303RS-19,
H303RS-200, H303RS-28, H303RS-50, H303SS-115, H303SS-19, H303SS-200, H303SS28, H303SS-50, H307-4, H307-4LC, H3074LOT003, H334-1, H334-4, N3-20, N3-200,
N3S-4, NC9173152, NC9329454, NC9415154, NC9431115, NC9480082, NC9693916,
NC9851780, NC9878676, O3386-20, S80032HPLC
Synonyms: n-Hexane; Hexyl hydride; Dipropyl; normal-Hexane; Hex.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
110-54-3
96-37-7
0-01-1
Chemical Name
Hexane
Methylcyclopentane
Various methylpentanes
Percent
EINECS/ELINCS
86.1
203-777-6
9.7
202-503-2
3.9-4.2
unlisted
Hazard Symbols: XN F N
Risk Phrases: 11 38 48/20
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: clear colorless liquid. Flash Point: -22 deg C. Aspiration hazard if swallowed.
Can enter lungs and cause damage. Danger! Extremely flammable liquid and vapor.
Vapor may cause flash fire. Possible risk of impaired fertility. Breathing vapors may cause
drowsiness and dizziness. Dangerous for the environment. May cause nervous system
effects. Causes eye, skin, and respiratory tract irritation.
Target Organs: Central nervous system, respiratory system, eyes, skin, peripheral
nervous system.
Potential Health Effects
Eye: Causes mild eye irritation. Causes redness and pain. May cause blurred vision,
tearing, and conjunctivitis.
Skin: Prolonged and/or repeated contact may cause defatting of the skin and dermatitis.
Causes irritation with burning pain, itching, and redness. Absorbed through the skin.
Ingestion: Aspiration hazard. May cause gastrointestinal irritation with nausea, vomiting
and diarrhea. Aspiration of material into the lungs may cause chemical pneumonitis,
which may be fatal. May cause central nervous system effects. Aspiration can cause
asphyxia, brain damage, and cardiac arrest.
Inhalation: Causes respiratory tract irritation. Exposure produces central nervous
system depression. Aspiration may cause respiratory swelling and pneumonitis.
Inhalation of high concentrations may cause narcotic effects. Vapors may cause dizziness
or suffocation. Exposure may cause vertigo, hallucinations, fatigue, muscle weakness,
visual disturbances, nervous system disturbances, coughing, chest pains, difficulty in
breathing, lung irritation, gastrointestinal disturbances, and edema which may be fatal.
Chronic: Prolonged or repeated skin contact may cause defatting and dermatitis.
Prolonged or repeated exposure may cause adverse reproductive effects. May cause fetal
effects. Chronic exposure may cause visual disturbances. Laboratory experiments have
resulted in mutagenic effects. Peripheral neuropathy symptoms include: muscular
weakness, paresthesia, numbing of the hands, feet, legs and arms, unsteadiness, and
difficulty in walking and standing. Repeated exposure may cause nervous system
abnormalities with muscle weakness and damage, motor incoordination, and sensation
disturbances. Chronic exposure produces peripheral neuropathy.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid.
Skin: In case of contact, flush skin with plenty of water. Remove contaminated clothing
and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion: Potential for aspiration if swallowed. Get medical aid immediately. Do not
induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively. For ingestion, the stomach
sould be intubated, aspirated, and lavaged with a slurry of activated charcoal--protect the
airway from aspiration of gastric contents. Monitor arterial blood gases in cases of severe
aspiration.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Vapors may form an explosive mixture with air. During a fire, irritating and highly toxic
gases may be generated by thermal decomposition or combustion. Use water spray to
keep fire-exposed containers cool. Extremely flammable liquid and vapor. Water may be
ineffective. Material is lighter than water and a fire may be spread by the use of water.
May accumulate static electrical charges, and may cause ignition of its own vapors.
Containers may explode if exposed to fire. Vapors are heavier than air and may travel to
a source of ignition and flash back. Vapors can spread along the ground and collect in low
or confined areas.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. Water may be ineffective. Water may spread fire. If water is the
only media available, use in flooding amounts. For large fires, use water spray, fog or
alcohol-resistant foam. Do NOT use straight streams of water. Contact professional firefighters immediately. Cool containers with flooding quantities of water until well after fire
is out.
Flash Point: -22 deg C ( -7.60 deg F)
Autoignition Temperature: 225 deg C ( 437.00 deg F)
Explosion Limits, Lower:1.1 vol %
Upper: 7.5 vol %
NFPA Rating: (estimated) Health: 1; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Avoid runoff into storm sewers and ditches which lead to
waterways. Clean up spills immediately, observing precautions in the Protective
Equipment section. Remove all sources of ignition. Provide ventilation. A vapor
suppressing foam may be used to reduce vapors. Use only non-sparking tools and
equipment.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Ground and bond containers when transferring material. Avoid contact with
eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor),
and can be dangerous. Take precautionary measures against static discharges. Keep
away from heat, sparks and flame. Do not pressurize, cut, weld, braze, solder, drill,
grind, or expose empty containers to heat, sparks or open flames. Use only with
adequate ventilation. Avoid breathing vapor or mist.
Storage: Keep away from heat and flame. Keep away from sources of ignition. Store in a
tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry,
well-ventilated area away from incompatible substances. Flammables-area.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or local explosionproof ventilation to keep airborne levels to acceptable levels.
Exposure Limits
Chemical Name
NIOSH
OSHA - Final PELs
50 ppm TWA (excluding
n-hexane); 180 mg/m3
TWA (excluding nhexane) 1100 ppm IDLH
500 ppm TWA; 1800
mg/m3 TWA
none listed
none listed
none listed
Various methylpentanes none listed
none listed
none listed
Hexane
Methylcyclopentane
ACGIH
50 ppm TWA; skin potential for cutaneous
absorption
OSHA Vacated PELs: Hexane: 50 ppm TWA; 180 mg/m3 TWA Methylcyclopentane: No
OSHA Vacated PELs are listed for this chemical. Various methylpentanes: No OSHA
Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear colorless
Odor: gasoline-like
pH: Not available.
Vapor Pressure: 151 mm Hg @ 25 deg C
Vapor Density: 2.97(Air = 1)
Evaporation Rate:Not available.
Viscosity: 0.31 mPas 20 C
Boiling Point: 69 deg C @ 760 mm Hg
Freezing/Melting Point:-95 deg C
Decomposition Temperature:Not available.
Solubility: Insoluble.
Specific Gravity/Density:0.6600
Molecular Formula:C6H14
Molecular Weight:86.18
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Ignition sources, excess heat, electrical sparks.
Incompatibilities with Other Materials: Strong oxidizing agents, dinitrogen
tetraoxide.
Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 110-54-3: MN9275000
CAS# 96-37-7: GY4640000
CAS# 0-01-1 unlisted.
LD50/LC50:
CAS# 110-54-3:
Draize test, rabbit, eye: 10 mg Mild;
Inhalation, rat: LC50 = 48000 ppm/4H;
Oral, rat: LD50 = 25 gm/kg;
CAS# 96-37-7:
CAS# 0-01-1:
Carcinogenicity:
CAS# 110-54-3: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 96-37-7: Not
listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 0-01-1: Not listed by ACGIH, IARC,
NIOSH, NTP, or OSHA.
Epidemiology: No data available.
Teratogenicity: Effects on Newborn - behavioral: Inhaltion, rat: TCLo = 10000 ppm/7H
(female 15 days pre-mating and female 1-18 days after conception).; Effects on Embryo
or Fetus - fetotoxicity: Inhalation, rat: TCLo = 5000 ppm/20 H (female 6-19 days after
conception).
Reproductive Effects: No data available.
Neurotoxicity: No data available.
Mutagenicity: Sex Chromosome Loss and Nondisjunction: Saccharomyces cerevisiae =
132 mmol/L.; Cytogenetic Anaylsis: Hamster fibroblast = 500 mg/L.
Other Studies: No data available.
Section 12 - Ecological Information
Ecotoxicity: No data available. Estimated BCF values = 2.24 and 2.89. These values
suggest that hexane will show low bioconcentration in aquatic organisms. Estimated Koc
value = 4.11. This product will show slight soil mobility and is expected to rapidly
volatilize from moist surface soils.
Environmental: Terrestrial: Volatilization and adsorption are expected to be the most
important fate processes. Aquatic: Photolysis or hydrolysis are not expected to be
important. Atmospheric: Expected to exist entirely in the vapor phase in ambient air,
expected half life 2.8 days. Expected to biodegrade but not bioconcentrate.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
HEXANES
Hazard Class: 3
UN Number:
Canada TDG
HEXANES
3
UN1208
Packing Group: II
UN1208
II
Additional
Info:
FLASHPOINT -22C
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 110-54-3 is listed on the TSCA inventory.
CAS# 96-37-7 is listed on the TSCA inventory.
CAS# 0-01-1 is not listed on the TSCA inventory. It is for research and development use
only.
Health & Safety Reporting List
CAS# 96-37-7: Effective 6/20/85; Sunset 11/9/93
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 110-54-3: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 110-54-3: acute, chronic, flammable. CAS # 96-37-7: flammable.
Section 313
This material contains Hexane (CAS# 110-54-3, 86 1%),which is subject to the reporting
requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 110-54-3 is listed as a hazardous air pollutant (HAP). This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 110-54-3 can be found on the following state right to know lists: New Jersey,
Pennsylvania, Minnesota, Massachusetts.
CAS# 96-37-7 can be found on the following state right to know lists: New Jersey,
Pennsylvania, Massachusetts.
CAS# 0-01-1 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN F N
Risk Phrases:
R 11 Highly flammable.
R 38 Irritating to skin.
R 48/20 Harmful : danger of serious damage to health
by prolonged exposure through inhalation.
R 62 Possible risk of impaired fertility.
R 51/53 Toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
R 65 Harmful: may cause lung damage if swallowed.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 29 Do not empty into drains.
S 33 Take precautionary measures against static
discharges.
S 36/37 Wear suitable protective clothing and
gloves.
S 9 Keep container in a well-ventilated place.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
S 62 If swallowed, do not induce vomiting: seek
medical advice immediately and show this container or
label.
WGK (Water Danger/Protection)
CAS# 110-54-3: 1
CAS# 96-37-7: 1
CAS# 0-01-1: No information available.
Canada - DSL/NDSL
CAS# 110-54-3 is listed on Canada's DSL List.
CAS# 96-37-7 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2A.
Canadian Ingredient Disclosure List
CAS# 110-54-3 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 110-54-3: OEL-AUSTRALIA:TWA 50 ppm (180 mg/m3) OEL-BELGIUM:TWA
50 ppm (176 mg/m3) OEL-DENMARK:TWA 50 ppm (180 mg/m3) OEL-FINLAND:T
WA 50 ppm (180 mg/m3);STEL 150 ppm (530 mg/m3) OEL-FRANCE:TWA 50 ppm
(170 mg/m3) OEL-GERMANY:TWA 50 ppm (180 mg/m3) OEL-HUNGARY:TWA 100 m
g/m3;STEL 200 mg/m3;Skin OEL-JAPAN:TWA 40 ppm (140 mg/m3);Skin OEL-T
HE NETHERLANDS:TWA 100 ppm (360 mg/m3) OEL-THE PHILIPPINES:TWA 500 pp
m (1800 mg/m3) JAN9 OEL-POLAND:TWA 400 mg/m3 OEL-RUSSIA:TWA 40 ppm;S
TEL 300 mg/m3 OEL-SWEDEN:TWA 25 ppm (90 mg/m3);STEL 50 ppm (180 mg/m3
) OEL-SWITZERLAND:TWA 50 ppm (180 mg/m3);STEL 100 ppm (360 mg/m3) OE
L-TURKEY:TWA 500 ppm (1800 mg/m3) OEL-UNITED KINGDOM:TWA 100 ppm (360
mg/m3);STEL 125 ppm OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check A
CGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 6/03/1999
Revision #8 Date: 1/15/2004
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Histoprep 80% alcohol
ACC# 89648
Section 1 - Chemical Product and Company Identification
MSDS Name: Histoprep 80% alcohol
Catalog Numbers: HC1200, HC12001GL, HC1400, HC14001LG
Synonyms: None.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
64-17-5
7732-18-5
Chemical Name
Percent
EINECS/ELINCS
Ethyl alcohol
72
200-578-6
Water
20
231-791-2
67-56-1
Methyl alcohol
4
200-659-6
67-63-0
Isopropyl alcohol
4
200-661-7
Hazard Symbols: XN F
Risk Phrases: 11 20/21/22
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: Colourless. Flash Point: 13 deg C. Flammable liquid and vapor. Harmful if
inhaled. May cause skin irritation. May cause respiratory and digestive tract irritation.
May cause severe eye irritation and possible injury. May cause central nervous system
depression. May cause liver and kidney damage. Cannot be made non-poisonous. May
cause reproductive and fetal effects. Danger! Poison! May be fatal or cause blindness if
swallowed. May form explosive peroxides. May be absorbed through intact skin. Causes
severe eye irritation. Causes respiratory tract irritation. Causes moderate skin irritation.
This substance has caused adverse reproductive and fetal effects in humans. Warning!
May cause liver, kidney and heart damage.
Target Organs: Kidneys, heart, central nervous system, liver.
Potential Health Effects
Eye: May cause severe eye irritation. Causes severe eye irritation. May cause painful
sensitization to light. Vapors may cause eye irritation. May cause chemical conjunctivitis
and corneal damage.
Skin: May cause skin irritation. Causes moderate skin irritation. Prolonged and/or
repeated contact may cause defatting of the skin and dermatitis. May be absorbed
through the skin. May cause cyanosis of the extremities.
Ingestion: May be fatal or cause blindness if swallowed. May cause gastrointestinal
irritation with nausea, vomiting and diarrhea. May cause systemic toxicity with acidosis.
May cause liver and kidney damage. May cause central nervous system depression,
characterized by excitement, followed by headache, dizziness, drowsiness, and nausea.
Advanced stages may cause collapse, unconsciousness, coma and possible death due to
respiratory failure.
Inhalation: Inhalation of high concentrations may cause central nervous system effects
characterized by nausea, headache, dizziness, unconsciousness and coma. Causes
respiratory tract irritation. May cause respiratory tract irritation. May cause effects similar
to those described for ingestion. May cause narcotic effects in high concentration. May
cause drowsiness, unconsciousness, and central nervous system depression. Vapors may
cause dizziness or suffocation.
Chronic: Prolonged or repeated eye contact may cause conjunctivitis. Prolonged or
repeated skin contact may cause defatting and dermatitis. Prolonged or repeated
exposure may cause adverse reproductive effects. May cause liver and kidney damage.
May cause reproductive and fetal effects. Laboratory experiments have resulted in
mutagenic effects. Animal studies have reported the development of tumors. Prolonged
exposure may cause liver, kidney, and heart damage.
Section 4 - First Aid Measures
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the
upper and lower eyelids. Immediately flush eyes with plenty of water for at least 15
minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Get medical aid
immediately.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Call a poison control center. If swallowed, do not induce vomiting unless
directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively. Persons with skin or eye
disorders or liver, kidney, chronic respiratory diseases, or central and peripheral nervous
sytem diseases may be at increased risk from exposure to this substance.
Antidote: None reported.
Section 5 - Fire Fighting Measures
General Information: Containers can build up pressure if exposed to heat and/or fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/
NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive
mixture with air. Vapors can travel to a source of ignition and flash back. Will burn if
involved in a fire. Flammable Liquid. Can release vapors that form explosive mixtures at
temperatures above the flashpoint. Use water spray to keep fire-exposed containers cool.
Containers may explode in the heat of a fire. Flammable liquid and vapor. May form
explosive peroxides. Vapors may be heavier than air. They can spread along the ground
and collect in low or confined areas.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam.
Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use
straight streams of water. For large fires, use dry chemical, carbon dioxide, alcoholresistant foam, or water spray. For small fires, use carbon dioxide, dry chemical, dry
sand, or alcohol-resistant foam. Cool containers with flooding quantities of water until
well after fire is out.
Flash Point: 13 deg C ( 55.40 deg F)
Autoignition Temperature: Not available.
Explosion Limits, Lower:2.1
Upper: 36.0
NFPA Rating: (estimated) Health: 2; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Remove all sources of ignition. Use a spark-proof tool. Provide
ventilation. A vapor suppressing foam may be used to reduce vapors. Water spray may
reduce vapor but may not prevent ignition in closed spaces.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Use only in a well-ventilated area. Use with
adequate ventilation. Ground and bond containers when transferring material. Use sparkproof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing.
Empty containers retain product residue, (liquid and/or vapor), and can be dangerous.
Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion
and inhalation. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill,
grind, or expose empty containers to heat, sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition.
Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a
cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Do
not store near perchlorates, peroxides, chromic acid or nitric acid.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility and a safety shower.
Use adequate general or local exhaust ventilation to keep airborne concentrations below
the permissible exposure limits.
Exposure Limits
Chemical Name
Ethyl alcohol
Water
Methyl alcohol
Isopropyl alcohol
ACGIH
1000 ppm TWA
none listed
NIOSH
OSHA - Final PELs
1000 ppm TWA; 1900
mg/m3 TWA 3300 ppm
IDLH
1000 ppm TWA; 1900
mg/m3 TWA
none listed
none listed
200 ppm TWA; 250
ppm STEL; skin potential for cutaneous
absorption
200 ppm TWA; 260 mg/ 200 ppm TWA; 260 mg/
m3 TWA 6000 ppm IDLH
m3 TWA
200 ppm TWA; 400
ppm STEL
400 ppm TWA; 980 mg/ 400 ppm TWA; 980 mg/
m3 TWA 2000 ppm IDLH
m3 TWA
OSHA Vacated PELs: Ethyl alcohol: 1000 ppm TWA; 1900 mg/m3 TWA Water: No
OSHA Vacated PELs are listed for this chemical. Methyl alcohol: 200 ppm TWA; 260 mg/
m3 TWA Isopropyl alcohol: 400 ppm TWA; 980 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use. Follow the OSHA respirator regulations
found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or
European Standard EN 149 approved respirator when necessary.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: Colourless
Odor: aromatic odor
pH: Not available.
Vapor Pressure: 44 mm Hg @20C
Vapor Density: >1.0
Evaporation Rate:>1
Viscosity: Not available.
Boiling Point: 64-83C
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:.7905
Molecular Formula:Not available.
Molecular Weight:Not available.
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures. Stability
unknown. This material may be sensitive to peroxide formation.
Conditions to Avoid: High temperatures, incompatible materials, ignition sources,
excess heat, oxidizers.
Incompatibilities with Other Materials: Strong oxidizing agents, acids, alkali metals,
ammonia, hydrazine, peroxides, sodium, acid anhydrides, calcium hypochlorite, chromyl
chloride, nitrosyl perchlorate, bromine pentafluoride, perchloric acid, silver nitrate,
mercuric nitrate, potassium-tert-butoxide, magnesium perchlorate, acid chlorides,
platinum, uranium hexafluoride, silver oxide, iodine heptafluoride, acetyl bromide,
disulfuryl difluoride, tetrachlorosilane + water, acetyl chloride, permanganic acid,
ruthenium (VIII) oxide, uranyl perchlorate, potassium dioxide.
Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide.
Hazardous Polymerization: Has not been reported
Section 11 - Toxicological Information
RTECS#:
CAS# 64-17-5: KQ6300000
CAS# 7732-18-5: ZC0110000
CAS# 67-56-1: PC1400000
CAS# 67-63-0: NT8050000
LD50/LC50:
CAS# 64-17-5:
Draize test, rabbit, eye: 500 mg Severe;
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, skin: 20 mg/24H Moderate;
Inhalation, mouse: LC50 = 39 gm/m3/4H;
Inhalation, rat: LC50 = 20000 ppm/10H;
Oral, mouse: LD50 = 3450 mg/kg;
Oral, rabbit: LD50 = 6300 mg/kg;
Oral, rat: LD50 = 7060 mg/kg;
Oral, rat: LD50 = 9000 mg/kg;
CAS# 7732-18-5:
Oral, rat: LD50 = >90 mL/kg;
CAS# 67-56-1:
Draize test, rabbit, eye: 40 mg Moderate;
Draize test, rabbit, eye: 100 mg/24H Moderate;
Draize test, rabbit, skin: 20 mg/24H Moderate;
Inhalation, rabbit: LC50 = 81000 mg/m3/14H;
Inhalation, rat: LC50 = 64000 ppm/4H;
Oral, mouse: LD50 = 7300 mg/kg;
Oral, rabbit: LD50 = 14200 mg/kg;
Oral, rat: LD50 = 5600 mg/kg;
Skin, rabbit: LD50 = 15800 mg/kg;
CAS# 67-63-0:
Draize test, rabbit, eye: 100 mg Severe;
Draize test, rabbit, eye: 10 mg Moderate;
Draize test, rabbit, eye: 100 mg/24H Moderate;
Draize test, rabbit, skin: 500 mg Mild;
Inhalation, mouse: LC50 = 53000 mg/m3;
Inhalation, rat: LC50 = 16000 ppm/8H;
Inhalation, rat: LC50 = 72600 mg/m3;
Oral, mouse: LD50 = 3600 mg/kg;
Oral, mouse: LD50 = 3600 mg/kg;
Oral, rabbit: LD50 = 6410 mg/kg;
Oral, rat: LD50 = 5045 mg/kg;
Oral, rat: LD50 = 5000 mg/kg;
Skin, rabbit: LD50 = 12800 mg/kg;
Carcinogenicity:
CAS# 64-17-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 7732-18-5: Not
listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 67-56-1: Not listed by ACGIH, IARC,
NIOSH, NTP, or OSHA. CAS# 67-63-0:
IARC: IARC Group 3 - not classifiable
Epidemiology: Ethanol has been shown to produce fetotoxicity in the embry o or fetus
of laboratory animals. Prenatal exposure to ethanol is associated with a distinct pattern of
co ngenital malformations that have collecetively been termed the "fetal alcohol
syndrome".
Teratogenicity: Oral, Human - woman: TDLo = 41 gm/kg (female 41 week(s) after
conception) Effects on Newborn - Apgar score (human only) and Effects on Newborn other neonatal measures or effects and Effects on Newborn - drug dependence.
Reproductive Effects: Intrauterine, Human - woman: TDLo = 200 mg/kg (female 5 day
(s) pre-mating) Fertility - female fertility index (e.g. # females pregnant per # sperm
positive females; # females pregnant per # females mated).
Neurotoxicity: No information available.
Mutagenicity: DNA Inhibition: Human, Lymphocyte = 220 mmol/L.; Cytogenetic
Analysis: Human, Lymphocyte = 1160 gm/L.; Cytogenetic Analysis: Human, Fibroblast =
12000 ppm.; Cytogenetic Analysis: Human, Leukocyte = 1 pph/72H (Continuous).; Sister
Chromatid Exchange: Human, Lymphocyte = 500 ppm/72H (Continuous).
Other Studies: Standard Draize Test(Skin, rabbit) = 20 mg/24H (Moderate) S tandard
Draize Test: Administration into the eye (rabbit) = 500 mg (Severe).
Section 12 - Ecological Information
Ecotoxicity: Fish: Rainbow trout: LC50 = 12900-15300 mg/L; 96 Hr; Flow-through @
24-24.3°CFish: Rainbow trout: LC50 = 11200 mg/L; 24 Hr; Fingerling (Unspecified)
Bacteria: Phytobacterium phosphoreum: EC50 = 34900 mg/L; 5-30 min; Microtox
testFish: Rainbow trout: LC50 = 12900-15300 mg/L; 96 Hr; Flow-through @ 24-24.3°
CFish: Rainbow trout: LC50 = 11200 mg/L; 24 Hr; Fingerling (Unspecified)Bacteria:
Phytobacterium phosphoreum: EC50 = 34900 mg/L; 5-30 min; Microtox test When
spilled on land it is apt to volatilize, biodegrade, and leach into the ground water, but no
data on the rates of these processes could be found. Its fate in ground water is unknown.
When released into water it will volatilize and probably biodegrade. It would not be
expected to adsorb to sediment or bioconcentrate in fish.
Environmental: When released to the atmosphere it will photodegrade in hours
(polluted urban atmosphere) to an estimated range of 4 to 6 days in less polluted areas.
Rainout should be significant.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 67-56-1: waste number U154 (Ignitable waste).
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
ALCOHOLS,
N.O.S.
Canada TDG
No information
available.
Hazard Class: 3
UN Number:
UN1987
Packing Group: II
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 64-17-5 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
CAS# 67-56-1 is listed on the TSCA inventory.
CAS# 67-63-0 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 67-63-0: Effective 12/15/86; Sunset 12/15/96
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 67-56-1: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 64-17-5: acute, chronic, flammable. CAS # 67-56-1: acute, flammable. CAS # 6763-0: acute, chronic, flammable.
Section 313
This material contains Methyl alcohol (CAS# 67-56-1, 4%),which is subject to the
reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373. This
material contains Isopropyl alcohol (CAS# 67-63-0, 4%),which is subject to the reporting
requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 67-56-1 is listed as a hazardous air pollutant (HAP). This material does not contain
any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 64-17-5 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 67-56-1 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 67-63-0 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
WARNING: This product contains Ethyl alcohol, a chemical known to the state of
California to cause birth defects or other reproductive harm. California No Significant Risk
Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN F
Risk Phrases:
R 11 Highly flammable.
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 24/25 Avoid contact with skin and eyes.
S 33 Take precautionary measures against static
discharges.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 7 Keep container tightly closed.
S 9 Keep container in a well-ventilated place.
WGK (Water Danger/Protection)
CAS# 64-17-5: 0
CAS# 7732-18-5: No information available.
CAS# 67-56-1: 1
CAS# 67-63-0: 1
Canada - DSL/NDSL
CAS# 64-17-5 is listed on Canada's DSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
CAS# 67-56-1 is listed on Canada's DSL List.
CAS# 67-63-0 is listed on Canada's DSL List.
Canada - WHMIS
WHMIS: Not available.
Canadian Ingredient Disclosure List
CAS# 64-17-5 is listed on the Canadian Ingredient Disclosure List.
CAS# 67-56-1 is listed on the Canadian Ingredient Disclosure List.
CAS# 67-63-0 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 64-17-5: OEL-AUSTRALIA:TWA 1000 ppm (1900 mg/m3) OEL-BELGIUM:T
WA 1000 ppm (1880 mg/m3) OEL-CZECHOSLOVAKIA:TWA 1000 mg/m3;STEL 5000
mg/m3 OEL-DENMARK:TWA 1000 ppm (1900 mg/m3) OEL-FINLAND:TWA 1000 ppm
(1900 mg/m3);STEL 1250 ppm (2400 mg/m3) OEL-FRANCE:TWA 1000 ppm (190
0 mg/m3);STEL 5000 pp OEL-GERMANY:TWA 1000 ppm (1900 mg/m3) OEL-HUNG
ARY:TWA 1000 mg/m3;STEL 3000 mg/m3 OEL-THE NETHERLANDS:TWA 1000 ppm (
1900 mg/m3) OEL-THE PHILIPPINES:TWA 1000 ppm (1900 mg/m3) OEL-POLAND
:TWA 1000 mg/m3 OEL-RUSSIA:STEL 1000 mg/m3 OEL-SWEDEN:TWA 1000 ppm (
1900 mg/m3) OEL-SWITZERLAND:TWA 1000 ppm (1900 mg/m3) OEL-THAILAND:T
WA 1000 ppm (1900 mg/m3) OEL-TURKEY:TWA 1000 ppm (1900 mg/m3) OEL-UN
ITED KINGDOM:TWA 1000 ppm (1900 mg/m3) JAN9 OEL IN BULGARIA, COLOMBIA
, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNA
M check ACGI TLV
CAS# 67-56-1: OEL-ARAB Republic of Egypt:TWA 200 ppm (260 mg/m3);Ski
n OEL-AUSTRALIA:TWA 200 ppm (260 mg/m3);STEL 250 ppm;Skin OEL-BELGIU
M:TWA 200 ppm (262 mg/m3);STEL 250 ppm;Skin OEL-CZECHOSLOVAKIA:TWA 10
0 mg/m3;STEL 500 mg/m3 OEL-DENMARK:TWA 200 ppm (260 mg/m3);Skin OELFINLAND:TWA 200 ppm (260 mg/m3);STEL 250 ppm;Skin OEL-FRANCE:TWA 200
ppm (260 mg/m3);STEL 1000 ppm (1300 mg/m3) OEL-GERMANY:TWA 200 ppm (2
60 mg/m3);Skin OEL-HUNGARY:TWA 50 mg/m3;STEL 100 mg/m3;Skin JAN9 OEL
-JAPAN:TWA 200 ppm (260 mg/m3);Skin OEL-THE NETHERLANDS:TWA 200 ppm (
260 mg/m3);Skin OEL-THE PHILIPPINES:TWA 200 ppm (260 mg/m3) OEL-POLA
ND:TWA 100 mg/m3 OEL-RUSSIA:TWA 200 ppm;STEL 5 mg/m3;Skin OEL-SWEDEN
:TWA 200 ppm (250 mg/m3);STEL 250 ppm (350 mg/m3);Skin OEL-SWITZERLAN
D:TWA 200 ppm (260 mg/m3);STEL 400 ppm;Skin OEL-THAILAND:TWA 200 ppm
(260 mg/m3) OEL-TURKEY:TWA 200 ppm (260 mg/m3) OEL-UNITED KINGDOM:TW
A 200 ppm (260 mg/m3);STEL 250 ppm;Skin OEL IN BULGARIA, COLOMBIA, JO
RDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM ch
eck ACGI TLV
CAS# 67-63-0: OEL-AUSTRALIA:TWA 400 ppm (980 mg/m3);STEL 500 ppm (12
25 mg/m3) OEL-BELGIUM:TWA 400 ppm (985 mg/m3);STEL 500 ppm (1230 mg/m
3) OEL-DENMARK:TWA 200 ppm (490 mg/m3);Skin OEL-FRANCE:STEL 400 ppm
(980 mg/m3) OEL-GERMANY:TWA 400 ppm (980 mg/m3) OEL-JAPAN:STEL 400 p
pm (980 mg/m3) OEL-THE NETHERLANDS:TWA 400 ppm (980 mg/m3);Skin OELTHE PHILIPPINES:TWA 400 ppm (980 mg/m3) OEL-RUSSIA:STEL 400 ppm (10 m
g/m3) OEL-SWEDEN:TWA 150 ppm (350 mg/m3);STEL 250 ppm (600 mg/m3) OE
L-SWITZERLAND:TWA 400 ppm (980 mg/m3);STEL 800 ppm OEL-TURKEY:TWA 200
ppm (500 mg/m3) OEL-UNITED KINGDOM:TWA 400 ppm (980 mg/m3);STEL 500
ppm;Skin OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OE
L IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 7/30/1999
Revision #3 Date: 12/03/2002
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Hydrochloric acid 33-38% solution
ACC# 11155
Section 1 - Chemical Product and Company Identification
MSDS Name: Hydrochloric acid 33-38% solution
Catalog Numbers: AC124620000, AC124620010, AC124620025, AC124620100,
AC124620250, AC124630000, AC124630010, AC124630025, AC124635000,
AC352020000, AC423790000, AC423790025, AC423790250, AC423795000, S71942,
S71942MF, S74853, S74853SC, A142-212, A142P-20, A142P19, A144-212, A144-500,
A144-500LB, A144-612GAL, A144C-212, A144C-212EA, A144P-20, A144P19, A144S212, A144S-212EA, A144S-500, A144S500LC, A144SI-212, A466-1, A466-2, A466-250,
A466-2LC, A466-500, A481-212, A481-212LC, A485212, A485SAM1, A485SAM2,
A485SAM3, A508-212, A508-212003, A508-212LC, A508-4, A508-500, A508SK-212,
NC9123736, NC9532181, S71942SCMF, S71942SCND, S71943, S71943ND, S80038,
SA49, XXA481184
Synonyms: Muriatic acid; Chlorohydric acid; Hydrogen chloride in aqueous solution.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
Chemical Name
Percent
EINECS/ELINCS
7732-18-5
Water
62-67
231-791-2
7647-01-0
Hydrogen chloride
33-38
231-595-7
Hazard Symbols: C
Risk Phrases: 34 37
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless to slight yellow clear liquid. Danger! Causes eye and skin burns.
Causes severe digestive tract irritation with possible burns. Repeated or prolonged
exposure may cause erosion of exposed teeth. Corrosive to metal. May be fatal if inhaled
or swallowed. Causes severe respiratory tract irritation with possible burns.
Target Organs: Respiratory system, gastrointestinal system, teeth, eyes, skin.
Potential Health Effects
Eye: May cause irreversible eye injury. Vapor or mist may cause irritation and severe
burns. Contact with liquid is corrosive to the eyes and causes severe burns.
Skin: Contact with liquid is corrosive and causes severe burns and ulceration. The
severity of injury depends on the concentration of the solution and the duration of
exposure.
Ingestion: Causes severe digestive tract burns with abdominal pain, vomiting, and
possible death. May cause corrosion and permanent tissue destruction of the esophagus
and digestive tract.
Inhalation: May be fatal if inhaled. May cause severe irritation of the respiratory tract
with sore throat, coughing, shortness of breath and delayed lung edema. Causes
chemical burns to the respiratory tract. Causes corrosive action on the mucous
membranes.
Chronic: Prolonged or repeated skin contact may cause dermatitis. Repeated exposure
may cause erosion of teeth. Repeated exposure to low concentrations of HCl vapor or
mist may cause bleeding of nose and gums. Chronic bronchitis and gastritis have also
been reported.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid immediately.
Skin: In case of contact, immediately flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Get medical aid immediately.
Wash clothing before reuse.
Ingestion: If swallowed, do NOT induce vomiting. Get medical aid immediately. If victim
is fully conscious, give a cupful of water. Never give anything by mouth to an
unconscious person.
Inhalation: POISON material. If inhaled, get medical aid immediately. Remove victim to
fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician: Do NOT use sodium bicarbonate in an attempt to neutralize the
acid.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water
runoff can cause environmental damage. Dike and collect water used to fight fire. Not
flammable, but reacts with most metals to form flammable hydrogen gas. Use water
spray to keep fire-exposed containers cool. Vapors may be heavier than air. They can
spread along the ground and collect in low or confined areas. Containers may explode
when heated.
Extinguishing Media: Substance is noncombustible; use agent most appropriate to
extinguish surrounding fire.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 0; Instability: 1
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Isolate area and deny entry. Provide ventilation. Spill may be carefully neutralized with
lime (calcium oxide, CaO). A vapor suppressing foam may be used to reduce vapors.
Approach spill from upwind.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Contents may develop pressure upon prolonged storage. Do not get in
eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale.
Discard contaminated shoes. Keep away from strong bases and metals. Use caution when
opening. Do not use with metal spatula or other metal items. Do not breathe vapor or
mist. Use only with adequate ventilation or respiratory protection.
Storage: Store in a cool, dry, well-ventilated area away from incompatible substances.
Corrosives area. Do not store in metal containers. Store away from alkalies. Separate
from oxidizing materials.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible exposure limits. Use a
corrosion-resistant ventilation system.
Exposure Limits
Chemical Name
Water
ACGIH
none listed
Hydrogen chloride
2 ppm Ceiling
NIOSH
OSHA - Final PELs
none listed
none listed
50 ppm IDLH
5 ppm Ceiling; 7 mg/m3
Ceiling
OSHA Vacated PELs: Water: No OSHA Vacated PELs are listed for this chemical.
Hydrogen chloride: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear chemical goggles and face shield.
Skin: Wear appropriate gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Clear liquid
Appearance: colorless to slight yellow
Odor: strong, pungent
pH: 0.01
Vapor Pressure: 84 mm Hg @ 20 deg C(35%)
Vapor Density: 1.27 (air=1)
Evaporation Rate:> 1.00 (N-butyl acetate)
Viscosity: Not available.
Boiling Point: 83 deg C @ 760 mmHg(31%)
Freezing/Melting Point:-66 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:1.19 (38%)
Molecular Formula:HCl.H2O
Molecular Weight:36.46
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Excess heat.
Incompatibilities with Other Materials: Metals, strong oxidizing agents, strong
reducing agents, bases, acetic anhydride, alcohols, amines, sulfuric acid, vinyl acetate,
epoxides (e.g. butyl glycidyl ether), chlorosulfonic acid, carbides, beta-propiolactone,
ethyleneimine, propylene oxide, lithium silicides, 2-aminoethanol, 1,1-difluoroethylene,
magnesium boride, mercuric sulfate, aldehydes, cyanides, sulfides, phosphides.
Hazardous Decomposition Products: Hydrogen chloride, chlorine, hydrogen gas.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 7732-18-5: ZC0110000
CAS# 7647-01-0: MW4025000; MW4031000
LD50/LC50:
CAS# 7732-18-5:
Oral, rat: LD50 = >90 mL/kg;
CAS# 7647-01-0:
Inhalation, mouse: LC50 = 1108 ppm/1H;
Inhalation, mouse: LC50 = 8300 mg/m3/30M;
Inhalation, rat: LC50 = 3124 ppm/1H;
Inhalation, rat: LC50 = 45000 mg/m3/5M;
Inhalation, rat: LC50 = 8300 mg/m3/30M;
Oral, rabbit: LD50 = 900 mg/kg;
Carcinogenicity:
CAS# 7732-18-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 7647-01-0:
IARC: IARC Group 3 - not classifiable
Epidemiology: No data available.
Teratogenicity: Female rats were exposed to 450 mg/m3 for 1 hour either prior to
mating or on day 9 of pregnancy. Developmental effects were observed in the offspring.
However, this exposure caused toxic effects, including mortality, in the mothers.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: See actual entry in RTECS for complete information.
Other Studies: No data available.
Section 12 - Ecological Information
Ecotoxicity: Fish: Bluegill/Sunfish: 3.6 mg/L; 48Hr; Lethal (unspecified)Fish: Bluegill/
Sunfish: LC50; 96 Hr; pH 3.0-3.5 No data available.
Environmental: Rapidly hydrolyzes when exposed to water. Will exhibit extensive
evaporation from soil surfaces. Upon transport through the soil, hydrochloric acid will
dissolve some of the soil materials (especially those with carbonate bases) and the acid
will neutralize to some degree.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
HYDROCHLORIC
ACID
Hazard Class: 8
UN Number:
Packing
Group:
Canada TDG
HYDROCHLORIC
ACID
8
UN1789
II
UN1789
II
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 7732-18-5 is listed on the TSCA inventory.
CAS# 7647-01-0 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 7647-01-0: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
CAS# 7647-01-0: 500 lb TPQ
SARA Codes
CAS # 7647-01-0: acute.
Section 313
This material contains Hydrogen chloride (CAS# 7647-01-0, 33 38%),which is subject to
the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 7647-01-0 is listed as a hazardous air pollutant (HAP). This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
CAS# 7647-01-0 is listed as a Hazardous Substance under the CWA. None of the
chemicals in this product are listed as Priority Pollutants under the CWA. None of the
chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 7647-01-0 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
C
Risk Phrases:
R 34 Causes burns.
R 37 Irritating to respiratory system.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 7732-18-5: No information available.
CAS# 7647-01-0: 1
Canada - DSL/NDSL
CAS# 7732-18-5 is listed on Canada's DSL List.
CAS# 7647-01-0 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of E, D1A.
Canadian Ingredient Disclosure List
CAS# 7647-01-0 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 7647-01-0: OEL-AUSTRALIA:TWA 5 ppm (7 mg/m3) OEL-AUSTRIA:TWA 5
ppm (7 mg/m3) OEL-BELGIUM:STEL 5 ppm (7.7 mg/m3) OEL-DENMARK:STEL 5
ppm (7 mg/m3) OEL-FINLAND:STEL 5 ppm (7 mg/m3);Skin OEL-FRANCE:STEL
5 ppm (7.5 mg/m3) OEL-GERMANY:TWA 5 ppm (7 mg/m3) OEL-HUNGARY:STEL
5 mg/m3 OEL-JAPAN:STEL 5 ppm (7.5 mg/m3) OEL-THE NETHERLANDS:TWA 5 p
pm (7 mg/m3) OEL-THE PHILIPPINES:TWA 5 ppm (7 mg/m3) OEL-POLAND:TWA
5 mg/m3 OEL-RUSSIA:STEL 5 ppm (5 mg/m3) OEL-SWEDEN:STEL 5 ppm (8 mg/
m3) OEL-SWITZERLAND:TWA 5 ppm (7.5 mg/m3);STEL 10 ppm (15 mg/m3) OEL
-THAILAND:TWA 5 ppm (7 mg/m3) OEL-TURKEY:TWA 5 ppm (7 mg/m3) OEL-UNI
TED KINGDOM:TWA 5 ppm (7 mg/m3);STEL 5 ppm (7 mg/m3) OEL IN BULGARIA,
COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPOR
E, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 7/06/1999
Revision #13 Date: 3/01/2004
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Iodine Solutions 1N and Lugol
ACC# 40101
Section 1 - Chemical Product and Company Identification
MSDS Name: Iodine Solutions 1N and Lugol
Catalog Numbers: S71311, S71312, S75056, S75056-1, S750561, NC9803180, SI102500, SI78-500
Synonyms: None
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
Chemical Name
Percent
EINECS/ELINCS
7732-18-5
Water
72.0-85.
231-791-2
7681-11-0
Potassium iodide
9.8-19.0
231-659-4
7553-56-2
Iodine
4.9-9.0
231-442-4
Hazard Symbols: XN
Risk Phrases: 22
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: dark amber liquid. Caution! May cause eye and skin irritation. May cause
respiratory and digestive tract irritation.
Target Organs: Central nervous system, respiratory system, cardiovascular system.
Potential Health Effects
Eye: May cause eye irritation.
Skin: May cause skin irritation. May cause skin sensitization, an allergic reaction, which
becomes evident upon re-exposure to this material.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May
cause gastric disturbances and electrolytic imbalance.
Inhalation: May cause respiratory tract irritation.
Chronic: Chronic exposure can lead to iodism characterized by salivation, nasal
discharge, sneezing, conjunctivitis, fever, laryngitis, bronchitis, stomatitis, and skin
rashes.
Section 4 - First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid.
Skin: Flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give
anything by mouth to an unconscious person. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. Get medical aid if cough or other symptoms appear.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Material will not burn.
Extinguishing Media: Use extinguishing media most appropriate for the surrounding
fire.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Clean up spills immediately, observing precautions in the Protective
Equipment section. Cover with sand, dry lime or soda ash and place in a closed container
for disposal.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Use with adequate ventilation.
Storage: Store in a cool, dry place.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name
ACGIH
NIOSH
OSHA - Final PELs
Water
none listed
none listed
none listed
Potassium iodide
none listed
none listed
none listed
0.1 ppm Ceiling
2 ppm IDLH
0.1 ppm Ceiling; 1 mg/
m3 Ceiling
Iodine
OSHA Vacated PELs: Water: No OSHA Vacated PELs are listed for this chemical.
Potassium iodide: No OSHA Vacated PELs are listed for this chemical. Iodine: No OSHA
Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: dark amber
Odor: iodine-like
pH: Not available.
Vapor Pressure: 14 mm Hg
Vapor Density: 0.7
Evaporation Rate:>1
Viscosity: Not available.
Boiling Point: 100 deg C
Freezing/Melting Point:0 deg C
Decomposition Temperature:Not available.
Solubility: Soluble in water.
Specific Gravity/Density:1.0
Molecular Formula:Not applicable.
Molecular Weight:Not available.
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials.
Incompatibilities with Other Materials: Powdered aluminum, active metals, strong
reducing agents. Acetylene and acetaldehyde causes explosive reactions with iodine.
Mixtures with ammonium hydroxide form shock sensitive compounds.
Hazardous Decomposition Products: Hydrogen iodide, iodine, iodide ions (I-).
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 7732-18-5: ZC0110000
CAS# 7681-11-0: TT2975000
CAS# 7553-56-2: NN1575000
LD50/LC50:
CAS# 7732-18-5:
Oral, rat: LD50 = >90 mL/kg;
CAS# 7681-11-0:
CAS# 7553-56-2:
Oral, mouse: LD50 = 22 gm/kg;
Oral, rabbit: LD50 = 10 gm/kg;
Oral, rat: LD50 = 14 gm/kg;
Carcinogenicity:
CAS# 7732-18-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 7681-11-0:
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 7553-56-2: Not listed by
ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No data available.
Teratogenicity: Potassium iodide has been observed to cause developmental
abnormalities of the endocrine system in human fetuses.
Reproductive Effects: No data available.
Neurotoxicity: No data available.
Mutagenicity: No data available.
Other Studies: No data available.
Section 12 - Ecological Information
No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
CORROSIVE
LIQUIDS, N.
O.S.
Hazard Class: 8
UN Number:
Canada TDG
CORROSIVE
LIQUID NOS
(IODINE
SOLUTION)
8
UN1760
Packing Group: III
UN1760
III
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 7732-18-5 is listed on the TSCA inventory.
CAS# 7681-11-0 is listed on the TSCA inventory.
CAS# 7553-56-2 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 7681-11-0: acute, chronic. CAS # 7553-56-2: acute, chronic, flammable.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 7681-11-0 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 7553-56-2 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 22 Harmful if swallowed.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 7732-18-5: No information available.
CAS# 7681-11-0: 1
CAS# 7553-56-2: 1
Canada - DSL/NDSL
CAS# 7732-18-5 is listed on Canada's DSL List.
CAS# 7681-11-0 is listed on Canada's DSL List.
CAS# 7553-56-2 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D2A, E.
Canadian Ingredient Disclosure List
CAS# 7681-11-0 is listed on the Canadian Ingredient Disclosure List.
CAS# 7553-56-2 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 7553-56-2: OEL-ARAB Republic of Egypt:TWA 0.1 ppm (0.1 mg/m3)
OEL-AUSTRALIA:TWA 0.1 ppm (1 mg/m3) OEL-BELGIUM:STEL 0.1 ppm (1 mg/m3
) OEL-DENMARK:.STEL 1 ppm (1 mg/m3) OEL-FINLAND:STEL 0.1 ppm (1 mg/m
3);Skin OEL-FRANCE:STEL 0.1 ppm (1 mg/m3) OEL-GERMANY:TWA 0.1 ppm (1
mg/m3) OEL-HUNGARY:TWA 1 mg/m3;STEL 2 mg/m3 OEL-JAPAN:TWA 0.1 ppm (
1 mg/m3);STEL 1 mg/m3 JAN9 OEL-THE NETHERLANDS:TWA 0.1 ppm (1 mg/m3)
OEL-THE PHILIPPINES:TWA 0.1 ppm (1 mg/m3) OEL-POLAND:TWA 1 mg/m3 OE
L-RUSSIA:TWA 0.1 ppm;STEL 1 mg/m3;Skin OEL-SWEDEN:STEL 0.1 ppm (1 mg/
m3) OEL-SWITZERLAND:TWA 0.1 ppm (1 mg/m3);STEL 0.2 pp (2 mg/m3) OELTHAILAND:TWA 0.1 ppm (1 mg/m3) OEL-TURKEY:TWA 0.1 ppm (1 mg/m3) OELUNITED KINGDOM:STEL 0.1 ppm (1 mg/m3) OEL IN BULGARIA, COLOMBIA, JORD
AN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM chec
k ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 12/12/1997
Revision #3 Date: 3/18/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Isopropanol, p.a.
ACC# 95533
Section 1 - Chemical Product and Company Identification
MSDS Name: Isopropanol, p.a.
Catalog Numbers: AC184130000, AC184130010, AC184130025
Synonyms: Isopropanol; Dimethylcarbinol; sec-Propyl alcohol; Rubbing alcohol;
Petrohol; 1-Methylethanol; 1-Methylethyl alcohol; 2-Hydroxypropane; 2-Propyl alcohol;
Isopropyl alcohol; Propan-2-ol; IPA; 2-Propanol.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
CAS#
67-63-0
Chemical Name
2-Propanol
Percent
EINECS/ELINCS
>= 99.5
200-661-7
Hazard Symbols: XI F
Risk Phrases: 11 36
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless liquid. Flash Point: 12 deg C. Warning! May cause central nervous
system depression. May form explosive peroxides. Flammable liquid and vapor.
Hygroscopic (absorbs moisture from the air). Causes respiratory tract irritation.
Aspiration hazard if swallowed. Can enter lungs and cause damage. This material has
been reported to be susceptible to autoxidation and therefore should be classified as
peroxidizable. Causes eye irritation. Breathing vapors may cause drowsiness and
dizziness. Prolonged or repeated contact causes defatting of the skin with irritation,
dryness, and cracking.
Target Organs: Central nervous system, respiratory system, eyes, skin.
Potential Health Effects
Eye: Produces irritation, characterized by a burning sensation, redness, tearing,
inflammation, and possible corneal injury. May cause transient corneal injury. In the eyes
of a rabbit, 0.1 ml of 70% isopropyl alcohol caused conjun ctivitis, iritis, and corneal
opacity.
Skin: May cause irritation with pain and stinging, especially if the skin is abraded.
Isopropanol has a low potential to cause allergic skin reactions; however, rare cases of
allergic contact dermatitis have been reported. May be absorbed through intact skin.
Dermal absorption has been considered toxicologically insignificant. T he cases of deep
coma associated with skin contact are thought to be a consequence of gross isopropanol
vapor inhalation in rooms with inade quate ventilation, rather than being attributable to
percutaneous abso rption of isopropanol per se.
Ingestion: Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May
cause kidney damage. May cause central nervous system depression, characterized by
excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages
may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
Aspiration of material into the lungs may cause chemical pneumonitis, which may be
fatal. The probable oral lethal dose in humans is 240 ml (2696 mg/kg), but in gestion of
only 20 ml (224 mg/kg) has caused poisoning.
Inhalation: Inhalation of high concentrations may cause central nervous system effects
characterized by nausea, headache, dizziness, unconsciousness and coma. May cause
narcotic effects in high concentration. Causes upper respiratory tract irritation. Inhalation
of vapors may cause drowsiness and dizziness.
Chronic: Prolonged or repeated skin contact may cause defatting and dermatitis.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid.
Skin: In case of contact, flush skin with plenty of water. Remove contaminated clothing
and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion: Potential for aspiration if swallowed. Get medical aid immediately. Do not
induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Urine acetone test may be helpful in diagnosis. Hemodialysis
should be considered in severe intoxication. Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Vapors may form an explosive mixture with air. Use water spray to keep fire-exposed
containers cool. Flammable liquid and vapor. May form explosive peroxides. Vapors are
heavier than air and may travel to a source of ignition and flash back. Vapors can spread
along the ground and collect in low or confined areas.
Extinguishing Media: Water may be ineffective. Do NOT use straight streams of water.
For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray.
For small fires, use carbon dioxide, dry chemical, dry sand, or alcohol-resistant foam.
Cool containers with flooding quantities of water until well after fire is out.
Flash Point: 12 deg C ( 53.60 deg F)
Autoignition Temperature: 399 deg C ( 750.20 deg F)
Explosion Limits, Lower:2.0 vol %
Upper: 12.7 @ 200°F
NFPA Rating: (estimated) Health: 1; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Use water spray to dilute spill to a non-flammable mixture.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor
suppressing foam may be used to reduce vapors.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Ground and bond containers when transferring material. Use spark-proof
tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty
containers retain product residue, (liquid and/or vapor), and can be dangerous. Take
precautionary measures against static discharges. Keep container tightly closed. Do not
pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat,
sparks or open flames. Use only with adequate ventilation. Avoid breathing vapor or mist.
Do not allow to evaporate to near dryness.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition.
Do not store in direct sunlight. Store in a tightly closed container. Keep from contact with
oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible
substances. Flammables-area. After opening, purge container with nitrogen before
reclosing. Periodically test for peroxide formation on long-term storage. Addition of water
or appropriate reducing materials will lessen peroxide formation. Store protected from
moisture. Containers should be dated when opened and tested periodically for the
presence of peroxides. Should crystals form in a peroxidizable liquid, peroxidation may
have occurred and the product should be considered extremely dangerous. In this
instance, the container should only be opened remotely by professionals. All
peroxidizable substances should be stored away from heat and light and be protected
from ignition sources.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility and a safety shower.
Use adequate general or local exhaust ventilation to keep airborne concentrations below
the permissible exposure limits.
Exposure Limits
Chemical Name
2-Propanol
ACGIH
200 ppm TWA; 400
ppm STEL
NIOSH
OSHA - Final PELs
400 ppm TWA; 980 mg/ 400 ppm TWA; 980 mg/
m3 TWA 2000 ppm IDLH
m3 TWA
OSHA Vacated PELs: 2-Propanol: 400 ppm TWA; 980 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: colorless
Odor: alcohol-like
pH: Not available.
Vapor Pressure: 33 mm Hg @ 20 deg C
Vapor Density: 2.1 (Air=1)
Evaporation Rate:1.7 (n-butyl acetate=1)
Viscosity: 2.27 mPas @ 20C
Boiling Point: 82 deg C @ 760 mmHg
Freezing/Melting Point:-88 deg C
Decomposition Temperature:Not available.
Solubility: Miscible.
Specific Gravity/Density:0.7850 (water=1)
Molecular Formula:C3H8O
Molecular Weight:60.09
Section 10 - Stability and Reactivity
Chemical Stability: Under normal storage conditions, peroxidizable compounds can
form and accumulate peroxides which may explode when subjected to heat or shock. This
material is most hazardous when peroxide levels are concentrated by distillation or
evaporation. Isopropanol is susceptible to autoxidation and therefore should be classified
as peroxidizable.
Conditions to Avoid: Light, ignition sources, excess heat, exposure to moist air or
water.
Incompatibilities with Other Materials: Attacks some forms of plastics, rubbers, and
coatings., chlorine, carbony dichloride(phosgene), acetaldehyde, ethylene oxide,
isocyanates, amines, aluminum at high temperatures, strong oxidizing agents, strong
acids, ammonia, strong bases.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 67-63-0: NT8050000
LD50/LC50:
CAS# 67-63-0:
Draize test, rabbit, eye: 100 mg Severe;
Draize test, rabbit, eye: 10 mg Moderate;
Draize test, rabbit, eye: 100 mg/24H Moderate;
Draize test, rabbit, skin: 500 mg Mild;
Inhalation, mouse: LC50 = 53000 mg/m3;
Inhalation, rat: LC50 = 16000 ppm/8H;
Inhalation, rat: LC50 = 72600 mg/m3;
Oral, mouse: LD50 = 3600 mg/kg;
Oral, mouse: LD50 = 3600 mg/kg;
Oral, rabbit: LD50 = 6410 mg/kg;
Oral, rat: LD50 = 5045 mg/kg;
Oral, rat: LD50 = 5000 mg/kg;
Skin, rabbit: LD50 = 12800 mg/kg;
Carcinogenicity:
CAS# 67-63-0:
IARC: IARC Group 3 - not classifiable
Epidemiology: Experimental teratogenic and reproductive effects have been reported for
isopropanol. Early epidemiological studies hav e suggested an association between the
strong acid man ufacture of isopropyl alcohol and paranasal sinus cancer in workers.
Teratogenicity: A rat & rabbit developmental toxicity study showed no teratogenic
effects at doses that were clearly maternally toxic. In a separate rat study, no evidence
of developmental neurotoxicity was associated with gestational exposures to IPA up to
1200 mg/kg/d.
Reproductive Effects: See actual entry in RTECS for complete information.
Neurotoxicity: No information available.
Mutagenicity: See actual entry in RTECS for complete information.
Other Studies: Standard Draize Test: Administration onto the skin (rabbit) = 500 mg
(Mild). Standard Draize Test: Administration into the eye (rabbit) = 100 mg (Moderate).
Standard Draize Test : Administration into the eye = 10 mg (Moderate). Standard D raize
test: Administration into the eye (rabbit) = 100 mg/24 H (Moderate).
Section 12 - Ecological Information
Ecotoxicity: Fish: Fathead Minnow: >1000 ppm; 96h; LC50Daphnia: >1000 ppm; 96h;
LC50Fish: Gold orfe: 8970-9280 ppm; 48h; LC50 IPA has a high biochemical oxygen
demand and a potential to cause oxygen depletion in aqueous systems, a low potential to
affect aquatic organisms, a low potential to affect secondary waste treatment microbial
metabolism, a low potential to affect the germination of some plants, a high potential to
biodegrade (low persistence) with unacclimated microorganisms from activated sludge.
Environmental: No information available.
Physical: THOD: 2.40 g oxygen/gCOD: 2.23 g oxygen/gBOD-5: 1.19-1.72 g oxygen/g
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
ISOPROPANOL
Hazard Class: 3
UN Number:
UN1219
Packing Group: II
IATA
RID/ADR
IMO
Canada TDG
No information
available.
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 67-63-0 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 67-63-0: Effective 12/15/86; Sunset 12/15/96
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 67-63-0: acute, chronic, flammable.
Section 313
This material contains 2-Propanol (CAS# 67-63-0, 99 5%),which is subject to the
reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 67-63-0 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XI F
Risk Phrases:
R 11 Highly flammable.
R 36 Irritating to eyes.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 24/25 Avoid contact with skin and eyes.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 7 Keep container tightly closed.
WGK (Water Danger/Protection)
CAS# 67-63-0: 1
Canada - DSL/NDSL
CAS# 67-63-0 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2B.
Canadian Ingredient Disclosure List
CAS# 67-63-0 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 67-63-0: OEL-AUSTRALIA:TWA 400 ppm (980 mg/m3);STEL 500 ppm (12
25 mg/m3) OEL-BELGIUM:TWA 400 ppm (985 mg/m3);STEL 500 ppm (1230 mg/m
3) OEL-DENMARK:TWA 200 ppm (490 mg/m3);Skin OEL-FRANCE:STEL 400 ppm
(980 mg/m3) OEL-GERMANY:TWA 400 ppm (980 mg/m3) OEL-JAPAN:STEL 400 p
pm (980 mg/m3) OEL-THE NETHERLANDS:TWA 400 ppm (980 mg/m3);Skin OELTHE PHILIPPINES:TWA 400 ppm (980 mg/m3) OEL-RUSSIA:STEL 400 ppm (10 m
g/m3) OEL-SWEDEN:TWA 150 ppm (350 mg/m3);STEL 250 ppm (600 mg/m3) OE
L-SWITZERLAND:TWA 400 ppm (980 mg/m3);STEL 800 ppm OEL-TURKEY:TWA 200
ppm (500 mg/m3) OEL-UNITED KINGDOM:TWA 400 ppm (980 mg/m3);STEL 500
ppm;Skin OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OE
L IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 7/27/1999
Revision #9 Date: 10/11/2001
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Isopropyl Alcohol 70%
ACC# 89530
Section 1 - Chemical Product and Company Identification
MSDS Name: Isopropyl Alcohol 70%
Catalog Numbers: A459-1, A459-20, A459-4, A459-500, NC9019861, NC9024637,
NC9366627, NC9405257, NC9600878, NC9761180, S76791
Synonyms: Isopropanol; Dimethylcarbinol; sec-Propyl alcohol; Rubbing alcohol;
Petrohol; 1-Methylethanol; 1-Methylethyl alcohol; 2-Hydroxypropane; 2-Propyl alcohol;
Isopropyl alcohol; Propan-2-ol; IPA; 2-Propanol.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
67-63-0
7732-18-5
Chemical Name
Percent
EINECS/ELINCS
Isopropyl alcohol
70.0
200-661-7
Water
30.0
231-791-2
Hazard Symbols: XI F
Risk Phrases: 11 36
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless liquid. Flash Point: 64 deg F. Warning! May cause central nervous
system depression. Flammable liquid and vapor. Causes respiratory tract irritation.
Aspiration hazard if swallowed. Can enter lungs and cause damage. Causes eye irritation.
Breathing vapors may cause drowsiness and dizziness. Prolonged or repeated contact
causes defatting of the skin with irritation, dryness, and cracking.
Target Organs: Central nervous system, respiratory system, eyes, skin.
Potential Health Effects
Eye: Produces irritation, characterized by a burning sensation, redness, tearing,
inflammation, and possible corneal injury. May cause transient corneal injury. In the eyes
of a rabbit, 0.1 ml of 70% isopropyl alcohol caused conjun ctivitis, iritis, and corneal
opacity.
Skin: May cause irritation with pain and stinging, especially if the skin is abraded.
Isopropanol has a low potential to cause allergic skin reactions; however, rare cases of
allergic contact dermatitis have been reported. May be absorbed through intact skin.
Dermal absorption has been considered toxicologically insignificant. T he cases of deep
coma associated with skin contact are thought to be a consequence of gross isopropanol
vapor inhalation in rooms with inade quate ventilation, rather than being attributable to
percutaneous abso rption of isopropanol per se.
Ingestion: Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May
cause kidney damage. May cause central nervous system depression, characterized by
excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages
may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
Aspiration of material into the lungs may cause chemical pneumonitis, which may be
fatal. The probable oral lethal dose in humans is 240 ml (2696 mg/kg), but in gestion of
only 20 ml (224 mg/kg) has caused poisoning.
Inhalation: Inhalation of high concentrations may cause central nervous system effects
characterized by nausea, headache, dizziness, unconsciousness and coma. May cause
narcotic effects in high concentration. Causes upper respiratory tract irritation. Inhalation
of vapors may cause drowsiness and dizziness.
Chronic: Prolonged or repeated skin contact may cause defatting and dermatitis.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid.
Skin: In case of contact, flush skin with plenty of water. Remove contaminated clothing
and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion: Potential for aspiration if swallowed. Get medical aid immediately. Do not
induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Urine acetone test may be helpful in diagnosis. Hemodialysis
should be considered in severe intoxication. Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Vapors may form an explosive mixture with air. Use water spray to keep fire-exposed
containers cool. Flammable liquid and vapor. Vapors are heavier than air and may travel
to a source of ignition and flash back. Vapors can spread along the ground and collect in
low or confined areas.
Extinguishing Media: Water may be ineffective. Do NOT use straight streams of water.
For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray.
For small fires, use carbon dioxide, dry chemical, dry sand, or alcohol-resistant foam.
Cool containers with flooding quantities of water until well after fire is out.
Flash Point: 64e deg F ( 17.78 deg C)
Autoignition Temperature: 399 deg C ( 750.20 deg F)
Explosion Limits, Lower:2.0 vol %
Upper: 12.7 @ 200°F
NFPA Rating: (estimated) Health: 1; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Use water spray to dilute spill to a non-flammable mixture.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor
suppressing foam may be used to reduce vapors.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Ground and bond containers when transferring material. Use spark-proof
tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty
containers retain product residue, (liquid and/or vapor), and can be dangerous. Take
precautionary measures against static discharges. Keep container tightly closed. Do not
pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat,
sparks or open flames. Use only with adequate ventilation. Avoid breathing vapor or mist.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition.
Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a
cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility and a safety shower.
Use adequate general or local exhaust ventilation to keep airborne concentrations below
the permissible exposure limits.
Exposure Limits
Chemical Name
Isopropyl alcohol
Water
ACGIH
200 ppm TWA; 400
ppm STEL
NIOSH
OSHA - Final PELs
400 ppm TWA; 980 mg/ 400 ppm TWA; 980 mg/
m3 TWA 2000 ppm IDLH
m3 TWA
none listed
none listed
none listed
OSHA Vacated PELs: Isopropyl alcohol: 400 ppm TWA; 980 mg/m3 TWA Water: No
OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: colorless
Odor: alcohol-like
pH: Not available.
Vapor Pressure: 33 mm Hg @ 20 deg C
Vapor Density: 2.1 (Air=1)
Evaporation Rate:1.7 (n-butyl acetate=1)
Viscosity: 2.27 mPas @ 20C
Boiling Point: 82 deg C @ 760 mmHg
Freezing/Melting Point:-88 deg C
Decomposition Temperature:Not available.
Solubility: Miscible.
Specific Gravity/Density:0.7850 (water=1)
Molecular Formula:C3H8O
Molecular Weight:60.09
Section 10 - Stability and Reactivity
Chemical Stability: Stable.
Conditions to Avoid: Ignition sources, excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents, strong acids, strong
bases, amines, ammonia, ethylene oxide, isocyanates, acetaldehyde, chlorine, phosgene,
Attacks some forms of plastics, rubbers, and coatings., aluminum at high temperatures.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 67-63-0: NT8050000
CAS# 7732-18-5: ZC0110000
LD50/LC50:
CAS# 67-63-0:
Draize test, rabbit, eye: 100 mg Severe;
Draize test, rabbit, eye: 10 mg Moderate;
Draize test, rabbit, eye: 100 mg/24H Moderate;
Draize test, rabbit, skin: 500 mg Mild;
Inhalation, mouse: LC50 = 53000 mg/m3;
Inhalation, rat: LC50 = 16000 ppm/8H;
Inhalation, rat: LC50 = 72600 mg/m3;
Oral, mouse: LD50 = 3600 mg/kg;
Oral, mouse: LD50 = 3600 mg/kg;
Oral, rabbit: LD50 = 6410 mg/kg;
Oral, rat: LD50 = 5045 mg/kg;
Oral, rat: LD50 = 5000 mg/kg;
Skin, rabbit: LD50 = 12800 mg/kg;
CAS# 7732-18-5:
Oral, rat: LD50 = >90 mL/kg;
Carcinogenicity:
CAS# 67-63-0:
IARC: IARC Group 3 - not classifiable CAS# 7732-18-5: Not listed by ACGIH, IARC,
NIOSH, NTP, or OSHA.
Epidemiology: Experimental teratogenic and reproductive effects have been reported for
isopropanol. Early epidemiological studies hav e suggested an association between the
strong acid man ufacture of isopropyl alcohol and paranasal sinus cancer in workers.
Teratogenicity: A rat & rabbit developmental toxicity study showed no teratogenic
effects at doses that were clearly maternally toxic. In a separate rat study, no evidence
of developmental neurotoxicity was associated with gestational exposures to IPA up to
1200 mg/kg/d.
Reproductive Effects: See actual entry in RTECS for complete information.
Neurotoxicity: No information available.
Mutagenicity: See actual entry in RTECS for complete information.
Other Studies: Standard Draize Test: Administration onto the skin (rabbit) = 500 mg
(Mild). Standard Draize Test: Administration into the eye (rabbit) = 100 mg (Moderate).
Standard Draize Test : Administration into the eye = 10 mg (Moderate). Standard D raize
test: Administration into the eye (rabbit) = 100 mg/24 H (Moderate).
Section 12 - Ecological Information
Ecotoxicity: Fish: Fathead Minnow: >1000 ppm; 96h; LC50Daphnia: >1000 ppm; 96h;
LC50Fish: Gold orfe: 8970-9280 ppm; 48h; LC50 IPA has a high biochemical oxygen
demand and a potential to cause oxygen depletion in aqueous systems, a low potential to
affect aquatic organisms, a low potential to affect secondary waste treatment microbial
metabolism, a low potential to affect the germination of some plants, a high potential to
biodegrade (low persistence) with unacclimated microorganisms from activated sludge.
Environmental: No information available.
Physical: THOD: 2.40 g oxygen/gCOD: 2.23 g oxygen/gBOD-5: 1.19-1.72 g oxygen/g
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
ISOPROPANOL
Hazard Class: 3
UN Number:
UN1219
Packing Group: II
Section 15 - Regulatory Information
US FEDERAL
Canada TDG
No information
available.
TSCA
CAS# 67-63-0 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 67-63-0: Effective 12/15/86; Sunset 12/15/96
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 67-63-0: acute, chronic, flammable.
Section 313
This material contains Isopropyl alcohol (CAS# 67-63-0, 70 0%),which is subject to the
reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 67-63-0 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XI F
Risk Phrases:
R 11 Highly flammable.
R 36 Irritating to eyes.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 24/25 Avoid contact with skin and eyes.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 7 Keep container tightly closed.
WGK (Water Danger/Protection)
CAS# 67-63-0: 1
CAS# 7732-18-5: No information available.
Canada - DSL/NDSL
CAS# 67-63-0 is listed on Canada's DSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2A.
Canadian Ingredient Disclosure List
CAS# 67-63-0 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 67-63-0: OEL-AUSTRALIA:TWA 400 ppm (980 mg/m3);STEL 500 ppm (12
25 mg/m3) OEL-BELGIUM:TWA 400 ppm (985 mg/m3);STEL 500 ppm (1230 mg/m
3) OEL-DENMARK:TWA 200 ppm (490 mg/m3);Skin OEL-FRANCE:STEL 400 ppm
(980 mg/m3) OEL-GERMANY:TWA 400 ppm (980 mg/m3) OEL-JAPAN:STEL 400 p
pm (980 mg/m3) OEL-THE NETHERLANDS:TWA 400 ppm (980 mg/m3);Skin OELTHE PHILIPPINES:TWA 400 ppm (980 mg/m3) OEL-RUSSIA:STEL 400 ppm (10 m
g/m3) OEL-SWEDEN:TWA 150 ppm (350 mg/m3);STEL 250 ppm (600 mg/m3) OE
L-SWITZERLAND:TWA 400 ppm (980 mg/m3);STEL 800 ppm OEL-TURKEY:TWA 200
ppm (500 mg/m3) OEL-UNITED KINGDOM:TWA 400 ppm (980 mg/m3);STEL 500
ppm;Skin OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OE
L IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 7/27/1999
Revision #7 Date: 10/12/2001
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Safety (MSDS) data for l-glutamine
General
Synonyms: l-(+)-glutamic acid-5-amide, 2-aminoglutaramic acid, levoglutamide,
(S)-(+)-glutamine
Molecular formula: C5H10N2O3
CAS No: 56-85-9
EINECS No: 200-292-1
Physical data
Appearance: white powder
Melting point: ca. 185 C (decomposes)
Boiling point:
Vapour density:
Vapour pressure:
Density (g cm-3):
Flash point:
Explosion limits:
Autoignition temperature:
Water solubility: soluble
Stability
Moisture and light sensitive. Incompatible with moisture, strong oxidising agents.
Toxicology
May act as a respiratory or eye irritant.
Toxicity data
(The meaning of any abbreviations which appear in this section is given here.)
ORL-RAT LD50 7500 mg kg-1
Risk phrases
(The meaning of any risk phrases which appear in this section is given here.)
Transport information
Non-hazardous for air, sea and road freight.
Personal protection
Minimize contact.
Safety phrases
(The meaning of any safety phrases which appear in this section is given here.)
[Return to Physical & Theoretical Chemistry Lab. Safety home page.]
This information was last updated on September 5, 2003. We have tried to make it as
accurate and useful as possible, but can take no responsibility for its use, misuse, or
accuracy. We have not verified this information, and cannot guarantee that it is up-to-date.
Material Safety Data Sheet
Methanol
ACC# 14280
Section 1 - Chemical Product and Company Identification
MSDS Name: Methanol
Catalog Numbers: S75162, S75163, S75959, S75965, S75965A, S75965HPLC,
S75965SPEC, A408-1, A408-4, A408-4LC, A408SK-4, A411-20, A411-4, A412-1, A41220, A412-200, A412-200LC, A412-4, A412-4LC, A412-500, A412-500LC, A412CU1300,
A412FB115, A412FB19, A412FB200, A412FB50, A412J500, A412P-4, A412P-4LC,
A412POP19, A412POP200, A412POP50, A412POPB19, A412POPB200, A412POPB50,
A412RB115, A412RB200, A412RB50, A412RS115, A412RS19, A412RS200, A412RS28,
A412RS50, A412SK-4, A412SS-115, A412SS-19, A412SS-200, A412SS28, A412SS50,
A413-20, A413-200, A413-4, A413-500, A433F-1GAL, A433P-4, A433P1GAL, A433RS50,
A433S-20, A433S-200, A433S-4, A434-20, A450-4, A452-1, A452-212, A452-4, A4524LC, A452J1, A452N119, A452N219, A452NB219, A452POP19, A452POP200,
A452POP28, A452POP50, A452POPN19, A452RS-115, A452RS-19, A452RS-200, A452RS28, A452RS-50, A452SK-1, A452SK-4, A452SS-115, A452SS-19, A452SS-200, A452SS50, A452SS28, A453-1, A453-1LC, A453-500, A453J1, A454-1, A454-1LC, A454-4, A4544LC, A454J1, A454POP19, A454POP200, A454POP50, A454RS-115, A454RS-200,
A454RS-28, A454SS-19, A454SS-28, A454SS-50, A454SS115, A454SS200, A455-1,
A455POP19, A455POP200, A455POP50, A455RS19, A455SS19, A455SS200, A455SS50,
A457-4, A935-4, A935FB200, A935POPB200, A935RB200, A947-4, A947-4LC,
A947POP19, A947POP200, A947POP50, A947RS-115, A947RS-200, A947RS-28, A947SS115, A947SS-19, A947SS-200, A947SS-28, A947SS-50, BP1105-1, BP1105-4,
BP1105POP19, BP1105POP20, BP1105POP50, BP1105SS115, BP1105SS19,
BP1105SS200, BP1105SS28, BP1105SS50, BP2618100, HC400 1GAL, NC9105104,
NC9115030, NC9125138, NC9134255, NC9173853, NC9905242, NC9942270,
NC9964975, SC95-1, SW2-1, TIA9474, TIA947P200L
Synonyms: Carbinol; Methyl alcohol; Methyl hydroxide; Monohydroxymethane; Wood
alcohol; Wood naptha; Wood spirits; Columbian spirits; Methanol.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
67-56-1
Chemical Name
Methanol
Percent
EINECS/ELINCS
>99.0
200-659-6
Hazard Symbols: T F
Risk Phrases: 11 23/24/25 39/23/24/25
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: clear, colorless liquid. Flash Point: 11 deg C. Poison! Cannot be made nonpoisonous. Causes eye and skin irritation. Danger! Flammable liquid and vapor. May
be fatal or cause blindness if swallowed. May cause central nervous system depression.
Causes respiratory tract irritation. Harmful if swallowed, inhaled, or absorbed through the
skin. Vapor harmful.
Target Organs: Eyes, nervous system, optic nerve.
Potential Health Effects
Eye: Methanol is a mild to moderate eye irritant. Inhalation, ingestion or skin absorption
of methanol can cause significant disturbances in vision, including blindness.
Skin: Causes moderate skin irritation. Harmful if absorbed through the skin. Prolonged
and/or repeated contact may cause defatting of the skin and dermatitis. Methanol can be
absorbed through the skin, producing systemic effects that include visual disturbances.
Ingestion: Harmful if swallowed. May be fatal or cause blindness if swallowed. Aspiration
hazard. May cause systemic toxicity with acidosis. May cause central nervous system
depression, characterized by excitement, followed by headache, dizziness, drowsiness,
and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible
death due to respiratory failure.
Inhalation: Methanol is toxic and can very readily form extremely high vapor
concentrations at room temperature. Inhalation is the most common route of
occupational exposure. At first, methanol causes CNS depression with nausea, headache,
vomiting, dizziness and incoordination. A time period with no obvious symptoms follows
(typically 8-24 hrs). This latent period is followed by metabolic acidosis and severe visual
effects which may include reduced reactivity and/or increased sensitivity to light, blurred,
double and/or snowy vision, and blindness. Depending on the severity of exposure and
the promptness of treatment, survivors may recover completely or may have permanent
blindness, vision disturbances and/or nervous system effects.
Chronic: Prolonged or repeated skin contact may cause dermatitis. Chronic exposure
may cause effects similar to those of acute exposure. Methanol is only very slowly
eliminated from the body. Because of this slow elimination, methanol should be regarded
as a cumulative poison. Though a single exposure may cause no effect, daily exposures
may result in the accumulation of a harmful amount. Methanol has produced fetotoxicity
in rats and teratogenicity in mice exposed by inhalation to high concentrations that did
not produce significant maternal toxicity.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid.
Skin: In case of contact, immediately flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Get medical aid immediately.
Wash clothing before reuse.
Ingestion: Potential for aspiration if swallowed. Get medical aid immediately. Do not
induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Effects may be delayed.
Antidote: Ethanol may inhibit methanol metabolism.
Section 5 - Fire Fighting Measures
General Information: Containers can build up pressure if exposed to heat and/or fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/
NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and
highly toxic gases may be generated by thermal decomposition or combustion. Use water
spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter
than water and a fire may be spread by the use of water. Flammable liquid and vapor.
Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors
can spread along the ground and collect in low or confined areas.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. Water may be ineffective. For large fires, use water spray, fog or
alcohol-resistant foam. Do NOT use straight streams of water.
Flash Point: 11 deg C ( 51.80 deg F)
Autoignition Temperature: 464 deg C ( 867.20 deg F)
Explosion Limits, Lower:6.0 vol %
Upper: 36.00 vol %
NFPA Rating: (estimated) Health: 1; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Use water spray to disperse the gas/vapor. Remove all
sources of ignition. Provide ventilation. A vapor suppressing foam may be used to reduce
vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Ground and bond containers when transferring material. Avoid contact with
eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor),
and can be dangerous. Keep container tightly closed. Do not ingest or inhale. Do not
pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat,
sparks or open flames. Use only with adequate ventilation. Keep away from heat, sparks
and flame. Avoid use in confined spaces. Avoid breathing vapor or mist.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition.
Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. Keep containers tightly closed.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility and a safety shower.
Use adequate general or local exhaust ventilation to keep airborne concentrations below
the permissible exposure limits.
Exposure Limits
Chemical Name
Methanol
ACGIH
200 ppm TWA; 250
ppm STEL; skin potential for cutaneous
absorption
NIOSH
OSHA - Final PELs
200 ppm TWA; 260 mg/ 200 ppm TWA; 260 mg/
m3 TWA 6000 ppm IDLH
m3 TWA
OSHA Vacated PELs: Methanol: 200 ppm TWA; 260 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear, colorless
Odor: alcohol-like - weak odor
pH: Not available.
Vapor Pressure: 127 mm Hg @ 25 deg C
Vapor Density: 1.11 (Air=1)
Evaporation Rate:5.2 (Ether=1)
Viscosity: 0.55 cP 20 deg C
Boiling Point: 64.7 deg C @ 760 mm Hg
Freezing/Melting Point:-98 deg C
Decomposition Temperature:Not available.
Solubility: miscible
Specific Gravity/Density:.7910 g/cm3 @ 20°C
Molecular Formula:CH4O
Molecular Weight:32.04
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: High temperatures, ignition sources, confined spaces.
Incompatibilities with Other Materials: Strong oxidizing agents, strong acids,
powdered aluminum, powdered magnesium.
Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide, formaldehyde.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 67-56-1: PC1400000
LD50/LC50:
CAS# 67-56-1:
Draize test, rabbit, eye: 40 mg Moderate;
Draize test, rabbit, eye: 100 mg/24H Moderate;
Draize test, rabbit, skin: 20 mg/24H Moderate;
Inhalation, rabbit: LC50 = 81000 mg/m3/14H;
Inhalation, rat: LC50 = 64000 ppm/4H;
Oral, mouse: LD50 = 7300 mg/kg;
Oral, rabbit: LD50 = 14200 mg/kg;
Oral, rat: LD50 = 5600 mg/kg;
Skin, rabbit: LD50 = 15800 mg/kg;
Carcinogenicity:
CAS# 67-56-1: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No data available.
Teratogenicity: There is no human information available. Methanol is considered to be a
potential developmental hazard based on animal data. In animal experiments, methanol
has caused fetotoxic or teratogenic effects without maternal toxicity.
Reproductive Effects: See actual entry in RTECS for complete information.
Neurotoxicity: ACGIH cites neuropathy, vision and CNS under TLV basis.
Mutagenicity: See actual entry in RTECS for complete information.
Other Studies: No data available.
Section 12 - Ecological Information
Ecotoxicity: Fish: Fathead Minnow: 29.4 g/L; 96 Hr; LC50 (unspecified)Fish: Goldfish:
250 ppm; 11 Hr; resulted in deathFish: Rainbow trout: 8000 mg/L; 48 Hr; LC50
(unspecified)Fish: Rainbow trout: LC50 = 13-68 mg/L; 96 Hr.; 12 degrees CFish:
Fathead Minnow: LC50 = 29400 mg/L; 96 Hr.; 25 degrees C, pH 7.63Fish: Rainbow
trout: LC50 = 8000 mg/L; 48 Hr.; UnspecifiedBacteria: Phytobacterium phosphoreum:
EC50 = 51,000-320,000 mg/L; 30 minutes; Microtox test No data available.
Environmental: Dangerous to aquatic life in high concentrations. Aquatic toxicity rating:
TLm 96>1000 ppm. May be dangerous if it enters water intakes. Methyl alcohol is
expected to biodegrade in soil and water very rapidly. This product will show high soil
mobility and will be degraded from the ambient atmosphere by the reaction with
photochemically produced hyroxyl radicals with an estimated half-life of 17.8 days.
Bioconcentration factor for fish (golden ide) < 10. Based on a log Kow of -0.77, the BCF
value for methanol can be estimated to be 0.2.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 67-56-1: waste number U154 (Ignitable waste).
Section 14 - Transport Information
US DOT
IATA
RID/ADR
IMO
Canada TDG
Shipping
Name:
METHANOL
(METHANOL)
Hazard Class: 3
UN Number:
METHANOL
(METHANOL)
3(6.1)
UN1230
Packing Group: II
UN1230
II
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 67-56-1 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 67-56-1: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 67-56-1: acute, flammable.
Section 313
This material contains Methanol (CAS# 67-56-1, 99 0%),which is subject to the reporting
requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 67-56-1 is listed as a hazardous air pollutant (HAP). This material does not contain
any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 67-56-1 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
TF
Risk Phrases:
R 11 Highly flammable.
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 39/23/24/25 Toxic : danger of very serious
irreversible effects through inhalation, in contact
with skin and if swallowed.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 7 Keep container tightly closed.
WGK (Water Danger/Protection)
CAS# 67-56-1: 1
Canada - DSL/NDSL
CAS# 67-56-1 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D1B, D2B.
Canadian Ingredient Disclosure List
CAS# 67-56-1 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 67-56-1: OEL-ARAB Republic of Egypt:TWA 200 ppm (260 mg/m3);Ski
n OEL-AUSTRALIA:TWA 200 ppm (260 mg/m3);STEL 250 ppm;Skin OEL-BELGIU
M:TWA 200 ppm (262 mg/m3);STEL 250 ppm;Skin OEL-CZECHOSLOVAKIA:TWA 10
0 mg/m3;STEL 500 mg/m3 OEL-DENMARK:TWA 200 ppm (260 mg/m3);Skin OELFINLAND:TWA 200 ppm (260 mg/m3);STEL 250 ppm;Skin OEL-FRANCE:TWA 200
ppm (260 mg/m3);STEL 1000 ppm (1300 mg/m3) OEL-GERMANY:TWA 200 ppm (2
60 mg/m3);Skin OEL-HUNGARY:TWA 50 mg/m3;STEL 100 mg/m3;Skin JAN9 OEL
-JAPAN:TWA 200 ppm (260 mg/m3);Skin OEL-THE NETHERLANDS:TWA 200 ppm (
260 mg/m3);Skin OEL-THE PHILIPPINES:TWA 200 ppm (260 mg/m3) OEL-POLA
ND:TWA 100 mg/m3 OEL-RUSSIA:TWA 200 ppm;STEL 5 mg/m3;Skin OEL-SWEDEN
:TWA 200 ppm (250 mg/m3);STEL 250 ppm (350 mg/m3);Skin OEL-SWITZERLAN
D:TWA 200 ppm (260 mg/m3);STEL 400 ppm;Skin OEL-THAILAND:TWA 200 ppm
(260 mg/m3) OEL-TURKEY:TWA 200 ppm (260 mg/m3) OEL-UNITED KINGDOM:TW
A 200 ppm (260 mg/m3);STEL 250 ppm;Skin OEL IN BULGARIA, COLOMBIA, JO
RDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM ch
eck ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 7/21/1999
Revision #11 Date: 10/21/2002
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Mineral Oil, Light and Heavy
ACC# 17996
Section 1 - Chemical Product and Company Identification
MSDS Name: Mineral Oil, Light and Heavy
Catalog Numbers: S66138, S76306, BP2629-1, NC9102587, NC9198812, NC9869157,
O121-1, O121-20, O121-4, O122-1, O122-4, O122-4LC, O2-20, O5-20, XX0121208LI,
XXO121208LI
Synonyms: White mineral oil (petroleum); saturated hydrocarbons.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
8042-47-5
Chemical Name
White mineral oil
Percent
EINECS/ELINCS
>99
232-455-8
Hazard Symbols: None listed.
Risk Phrases: None listed.
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: water-white liquid. Warning! Causes eye and skin irritation. Inhalation of a
mist of this material may cause irritation of the lungs.
Target Organs: Lungs.
Potential Health Effects
Eye: May cause eye irritation.
Skin: May cause skin irritation. Prolonged and/or repeated contact may cause defatting
of the skin and dermatitis. Chronic exposure may cause lung damage.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation: Causes respiratory tract irritation.
Chronic: Chronic exposure may cause lung damage.
Section 4 - First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid.
Skin: Flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give
anything by mouth to an unconscious person. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. Get medical aid
if cough or other symptoms appear.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion.
Extinguishing Media: For small fires, use water spray, dry chemical, carbon dioxide or
chemical foam.
Flash Point: > 360e deg F (> 182.22 deg C)
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 1; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Avoid runoff into storm sewers and ditches which lead to
waterways. Clean up spills immediately, observing precautions in the Protective
Equipment section. Remove all sources of ignition. Provide ventilation.
Section 7 - Handling and Storage
Handling: Use with adequate ventilation. Avoid contact with eyes, skin, and clothing.
Keep container tightly closed. Avoid breathing spray or mist.
Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area
away from incompatible substances.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits
Chemical Name
White mineral oil
ACGIH
none listed
NIOSH
OSHA - Final PELs
none listed
none listed
OSHA Vacated PELs: White mineral oil: No OSHA Vacated PELs are listed for this
chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or
European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved
respirator when necessary.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: water-white
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: <=33.5 cst @40C
Boiling Point: Not available.
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: Insoluble in water.
Specific Gravity/Density:0.818-0.905
Molecular Formula:Hydrocarbon
Molecular Weight:Not available.
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: High temperatures, ignition sources.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 8042-47-5: PY8047000
LD50/LC50:
Not available.
Carcinogenicity:
CAS# 8042-47-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information found.
Teratogenicity: No information found.
Reproductive Effects: No information found.
Neurotoxicity: No information found.
Mutagenicity: No information found.
Other Studies: See actual entry in RTECS for complete information.
Section 12 - Ecological Information
No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
No
information
available.
Canada TDG
No information
available.
Hazard Class:
UN Number:
Packing Group:
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 8042-47-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 8042-47-5: acute.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 8042-47-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 8042-47-5: No information available.
Canada - DSL/NDSL
CAS# 8042-47-5 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of Not controlled..
Canadian Ingredient Disclosure List
Exposure Limits
Section 16 - Additional Information
MSDS Creation Date: 9/02/1997
Revision #7 Date: 9/01/2004
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Phenol Liquid
ACC# 18384
Section 1 - Chemical Product and Company Identification
MSDS Name: Phenol Liquid
Catalog Numbers: A88I-500, A931I-1, A931I-200, A931I-4, A931I-500, S801181,
S801181MF
Synonyms: Carbolic acid; Phenylic acid; Hydroxybenzene; Monohydroxybenzene; Phenyl
hydroxide
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
Chemical Name
Percent
EINECS/ELINCS
108-95-2
Phenol
89
203-632-7
7732-18-5
Water
11
231-791-2
6153-56-6
Oxalic acid, dihydrate
0.01
unlisted
Hazard Symbols: T
Risk Phrases: 34 24/25
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless liquid. Flash Point: 175 deg F. Danger! May cause liver and kidney
damage. May cause central nervous system depression. Causes eye and skin burns. Air
sensitive. Hygroscopic (absorbs moisture from the air). Light sensitive. May be fatal if
inhaled, absorbed through the skin or swallowed. Causes severe respiratory tract
irritation with possible burns. Causes severe digestive tract irritation with possible burns.
Readily absorbed through the skin. Mutagen. Combustible liquid and vapor.
Target Organs: Blood, kidneys, central nervous system, liver, eyes, skin.
Potential Health Effects
Eye: Contact with liquid or vapor causes severe burns and possible irreversible eye
damage.
Skin: May be fatal if absorbed through the skin. Direct skin contact results in white,
wrinkled discoloration, followed by severe burns. Phenol may be absorbed through the
skin rapidly to c ause systemic poisoning and possible death due to effects on the CNS s
ystem, heart, blood vessels, lungs and kidneys.
Ingestion: May cause liver and kidney damage. May cause central nervous system
depression, characterized by excitement, followed by headache, dizziness, drowsiness,
and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible
death due to respiratory failure. May cause perforation of the digestive tract. Causes
digestive tract burns with immediate pain, swelling of the throat, convulsions, and
possible coma. Methemoglobinemia is characterized by dizziness, drowsiness, headache,
shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of
the blood), rapid heart rate and chocolate-brown colored blood. Overexposure may cause
methemoglobinemia. Human fatalities have been reported from acute poisoning. May
cause cardiac abnormalities.
Inhalation: Causes severe irritation of upper respiratory tract with coughing, burns,
breathing difficulty, and possible coma. May be fatal if exposed to high concentrations.
Aspiration may lead to pulmonary edema. May also cause pallor, loss of appetite, nausea,
vomiting, diarrhea, weakness, darkened urine, headache, sweating, convulsions, cyanosis
(bluish skin due to deficient oxygenation of the blood), unconsciousness, fatigue,
pulmonary edema & coma. Inhalation at high concentrations may cause CNS depression
and asphixiation.
Chronic: Chronic inhalation and ingestion may cause effects similar to those of acute
inhalation and ingestion. May cause reproductive and fetal effects. Effects may be
delayed. Laboratory experiments have resulted in mutagenic effects. Repeated skin
contact may cause dermatitis with dark pigmentation of the skin. Animal studies have
reported the development of tumors. Chronic exposures have been reported to cause
death from liver and kid ney damage.
Section 4 - First Aid Measures
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed.
Extensive irrigation with water is required (at least 30 minutes).
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes. Discard contaminated
clothing in a manner which limits further exposure. SPEEDY ACTION IS CRITICAL!
Destroy contaminated shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. SPEED IS
ESSENTIAL. A DOCTOR MUST BE NOTIFIED AT ONCE.
Inhalation: Remove from exposure and move to fresh air immediately. If breathing is
difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased
apply artificial respiration using oxygen and a suitable mechanical device such as a bag
and a mask. SPEED IS ESSENTIAL, OBTAIN MEDICAL AID IMMEDIATELY.
Notes to Physician: Persons with liver or kidney disease should not be exposed to
phenol for any length of time.
Antidote: Activated charcoal, followed by cathartic, may be preferred to ipecac induced
emesis or lavage in decontamination of the GI tract and preventing systemic absorption
of phenol.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Vapors may be heavier than air. They can spread along the
ground and collect in low or confined areas. Containers may explode when heated. Runoff
from fire control or dilution water may cause pollution. Combustible liquid and vapor.
Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam. Use water spray to cool fire-exposed containers.
Flash Point: 175e deg F ( 79.44 deg C)
Autoignition Temperature: 1319 deg F ( 715.00 deg C)
Explosion Limits, Lower:1.8
Upper: 8.6
NFPA Rating: (estimated) Health: 4; Flammability: 2; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Avoid runoff into storm sewers and ditches which lead to
waterways. Clean up spills immediately, observing precautions in the Protective
Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide
ventilation.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Do not get in eyes, on skin, or on clothing. Empty containers retain product
residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep
away from heat, sparks and flame. Do not ingest or inhale. Store protected from light.
Use only in a chemical fume hood. Discard contaminated shoes. Do not pressurize, cut,
weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open
flames.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition.
Keep container closed when not in use. Store in a tightly closed container. Keep from
contact with oxidizing materials. Keep refrigerated. (Store below 4°C/39°F.) Store
protected from moisture. Store protected from light.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility and a safety shower.
Use adequate general or local exhaust ventilation to keep airborne concentrations below
the permissible exposure limits.
Exposure Limits
Chemical Name
ACGIH
NIOSH
OSHA - Final PELs
5 ppm TWA; 19 mg/m3
TWA 250 ppm IDLH
5 ppm TWA; 19 mg/m3
TWA
Phenol
5 ppm TWA; skin potential for cutaneous
absorption
Water
none listed
none listed
none listed
Oxalic acid, dihydrate
none listed
none listed
none listed
OSHA Vacated PELs: Phenol: 5 ppm TWA; 19 mg/m3 TWA Water: No OSHA Vacated
PELs are listed for this chemical. Oxalic acid, dihydrate: No OSHA Vacated PELs are listed
for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: colorless
Odor: sweetish odor
pH: 6 aqueous solution.
Vapor Pressure: .35 mm Hg @25C
Vapor Density: 3.2
Evaporation Rate:<0.01 (butyl acetate=1)
Viscosity: 1.51 cp@80C
Boiling Point: 360 deg F
Freezing/Melting Point:109 deg F
Decomposition Temperature:Not available.
Solubility: 6.75% in water
Specific Gravity/Density:1.0576
Molecular Formula:C6H5OH
Molecular Weight:94.1
Section 10 - Stability and Reactivity
Chemical Stability: Stable.
Conditions to Avoid: Light, ignition sources, excess heat, exposure to moist air or
water.
Incompatibilities with Other Materials: Strong oxidizing agents, isocyanates,
acetaldehyde, calcium hypochlorite, peroxomonosulfuric acid, nitrobenzene, sodium
nitrite, aluminum chloride, peroxydisulfuric acid, 1,3-butadiene, boron trifluoride diethyl
ether.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 108-95-2: SJ3325000
CAS# 7732-18-5: ZC0110000
CAS# 6153-56-6 unlisted.
LD50/LC50:
CAS# 108-95-2:
Draize test, rabbit, eye: 5 mg Severe;
Draize test, rabbit, skin: 500 mg/24H Severe;
Draize test, rabbit, skin: 100 mg Mild;
Inhalation, mouse: LC50 = 177 mg/m3;
Inhalation, rat: LC50 = 316 mg/m3;
Oral, mouse: LD50 = 270 mg/kg;
Oral, rat: LD50 = 317 mg/kg;
Skin, rabbit: LD50 = 630 mg/kg;
Skin, rat: LD50 = 669 mg/kg;
CAS# 7732-18-5:
Oral, rat: LD50 = >90 mL/kg;
CAS# 6153-56-6:
Carcinogenicity:
CAS# 108-95-2:
IARC: IARC Group 3 - not classifiable CAS# 7732-18-5: Not listed by ACGIH, IARC,
NIOSH, NTP, or OSHA. CAS# 6153-56-6: Not listed by ACGIH, IARC, NIOSH, NTP, or
OSHA.
Epidemiology: The predominant acute action of a toxic dose of phenol in m an appears
to be to the central nervous system, lead ing to sudden collapse and unconsciousness.
Teratogenicity: Oral, rat: TDLo = 1200 mg/kg (female 6-15 day(s) after conception)
Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus).; Oral,
mouse: TDLo = 4 gm/kg (female 6-15 day(s) after conception) Specific Developmental
Abnormalities - musculoskeletal system.
Reproductive Effects: Oral, rat: TDLo = 300 mg/kg (female 6-15 day(s) after
conception) Fertility - post-implantation mortality (e.g. dead and/or resorbed implants
per total number of implants).
Neurotoxicity: No data available.
Mutagenicity: Mutation Test Systems - not otherwise specified: Human, HeLa cell = 17
mg/L.; DNA Inhibition: Human, HeLa cell = 1 mmol/L.; Mutation Test Systems - not
otherwise specified: Human, Lymphocyte = 5 umol/L.; Sister Chromatid Exchange:
Human, Lymphocyte = 5 umol/L.
Other Studies: Standard Draize Test: Administration onto the skin (rabbit) = 500
mg/24H (Severe). Standard Draize Test: Administra tion into the eye (rabbit) = 5 mg
(Severe).
Section 12 - Ecological Information
Ecotoxicity: Water flea Daphnia: EC50=12 mg/l; 48-hour; CAS# 108-95-2:
UnspecifiedWater flea Daphnia: EC50=4.0 mg/l; 96-hour; CAS# 108-95-2:
UnspecifiedFish: Fathead Minnow: LC50 > 50 mg/l; 1 Hr; CAS# 108-95-2 Static @ 18-22°
CFish: Fathead Minnow: TLm = 41 mg/L; 48-hour; CAS# 108-95-2: Flow-through @ 15°
CFish: Bluegill/Sunfish: TLm = 19 / 5.7 mg/L; 96 Hr; CAS# 108-95-2: Flow-through If
released to the environment, phenol's primary removal mechanism is biodegradation
which is generally rapid (days). If phenol is released to soil, it will readily leach and
biodegrade. The biodegradation in soil is generally rapid with half-lives of under 5 days
even in subsurface soils.
Environmental: Phenol does not bioconcentrate in aquatic organisms. In the
atmosphere, phenol occurs as a vapor and reacts with photochemically-produced
hydroxyl radicals resulting in a half-life of approximately 15 hours. During the nighttime,
it reacts with nitrate radicals with a resulting half-life of 12 minutes. Phenol has also been
shown to be readily removed from the atmosphere by rain.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 108-95-2: waste number U188.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
PHENOL
SOLUTIONS
Hazard Class: 6.1
UN Number:
Canada TDG
PHENOL, SOLID
6.1(9.2)
UN2821
Packing Group: II
UN1671
II
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 108-95-2 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
CAS# 6153-56-6 is not on the TSCA Inventory because it is a hydrate. It is considered to
be listed if the CAS number for the anhydrous form is on the inventory (40CFR720.3(u)
(2)).
Health & Safety Reporting List
CAS# 108-95-2: Effective 6/1/87; Sunset 6/1/97
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
CAS# 108-95-2: Present
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 108-95-2: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
CAS# 108-95-2: 500 lb TPQ (lower threshold); 10000 lb TPQ (upper thres hold)
SARA Codes
CAS # 108-95-2: acute, chronic, flammable. CAS # 6153-56-6: acute, chronic.
Section 313
This material contains Phenol (CAS# 108-95-2, 89%),which is subject to the reporting
requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 108-95-2 is listed as a hazardous air pollutant (HAP). This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
CAS# 108-95-2 is listed as a Hazardous Substance under the CWA. CAS# 108-95-2 is
listed as a Priority Pollutant under the Clean Water Act. CAS# 108-95-2 is listed as a
Toxic Pollutant under the Clean Water Act.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 108-95-2 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 6153-56-6 can be found on the following state right to know lists: Pennsylvania.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
T
Risk Phrases:
R 34 Causes burns.
R 24/25 Toxic in contact with skin and if swallowed.
Safety Phrases:
S 28 After contact with skin, wash immediately
with...
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 108-95-2: 2
CAS# 7732-18-5: No information available.
CAS# 6153-56-6: 1
Canada - DSL/NDSL
CAS# 108-95-2 is listed on Canada's DSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D1A, E, D2B, B3.
Canadian Ingredient Disclosure List
CAS# 108-95-2 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 108-95-2: OEL-ARAB Republic of Egypt:TWA 5 ppm (19 mg/m3);Skin
OEL-AUSTRALIA:TWA 5 ppm (19 mg/m3);Skin OEL-BELGIUM:TWA 5 ppm (19 mg
/m3);Skin OEL-CZECHOSLOVAKIA:TWA 20 mg/m3;STEL 40 mg/m3 OEL-DENMARK:
TWA 5 ppm (19 mg/m3);Skin OEL-FINLAND:TWA 5 ppm (19 mg/m3);STEL 10 pp
m (38 mg/m3);Skin OEL-FRANCE:TWA 5 ppm (19 mg/m3);Skin OEL-GERMANY:T
WA 5 ppm (19 mg/m3);Skin OEL-HUNGARY:TWA 4 mg/m3;STEL 8 mg/m3;Skin O
EL-JAPAN:TWA 5 ppm (19 mg/m3);Skin OEL-THE NETHERLANDS:TWA 5 ppm (19
mg/m3);Skin OEL-THE PHILIPPINES:TWA 5 ppm (10 mg/m3);Skin OEL-POLAND
:TWA 10 ppm OEL-RUSSIA:TWA 5 ppm;STEL 0.3 mg/m3;Skin OEL-SWEDEN:TWA
1 ppm (4 mg/m3);STEL 2 ppm (8 mg/m3);Skin OEL-SWITZERLAND:TWA 5 ppm (
19 mg/m3);STEL 10 ppm (38 mg/m3);Skin OEL-THAILAND:TWA 5 ppm (19 mg/m
3) OEL-TURKEY:TWA 5 ppm (19 mg/m3);Skin OEL-UNITED KINGDOM:TWA 5 ppm
(19 mg/m3);STEL 10 ppm;Skin OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA
check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TL
V
Section 16 - Additional Information
MSDS Creation Date: 6/01/1999
Revision #6 Date: 10/30/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Phenol, Crystallized
ACC# 18380
Section 1 - Chemical Product and Company Identification
MSDS Name: Phenol, Crystallized
Catalog Numbers: AC180780000, AC180781000, AC180785000, AC417170000,
AC417170250, AC417175000, A91I-212, A91I-500, A92-100, A92-112, A92-500, BP226100, BP226-500
Synonyms: Carbolic acid; Phenylic acid; Hydroxybenzene; Monohydroxybenzene; Phenyl
hydroxide
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
108-95-2
Chemical Name
Phenol
Percent
EINECS/ELINCS
ca.100
203-632-7
Hazard Symbols: T
Risk Phrases: 34 24/25
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: white solid. Flash Point: 79 deg C. Danger! May cause liver and kidney
damage. May cause central nervous system depression. Causes eye and skin burns. Air
sensitive. Hygroscopic (absorbs moisture from the air). Light sensitive. May be fatal if
inhaled, absorbed through the skin or swallowed. Causes severe respiratory tract
irritation with possible burns. Causes severe digestive tract irritation with possible burns.
Readily absorbed through the skin. Mutagen.
Target Organs: Blood, kidneys, central nervous system, liver, eyes, skin.
Potential Health Effects
Eye: Contact with liquid or vapor causes severe burns and possible irreversible eye
damage.
Skin: May be fatal if absorbed through the skin. Direct skin contact results in white,
wrinkled discoloration, followed by severe burns. Phenol may be absorbed through the
skin rapidly to c ause systemic poisoning and possible death due to effects on the CNS s
ystem, heart, blood vessels, lungs and kidneys.
Ingestion: May cause liver and kidney damage. May cause central nervous system
depression, characterized by excitement, followed by headache, dizziness, drowsiness,
and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible
death due to respiratory failure. May cause perforation of the digestive tract. Causes
digestive tract burns with immediate pain, swelling of the throat, convulsions, and
possible coma. Methemoglobinemia is characterized by dizziness, drowsiness, headache,
shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of
the blood), rapid heart rate and chocolate-brown colored blood. Overexposure may cause
methemoglobinemia. Human fatalities have been reported from acute poisoning. May
cause cardiac abnormalities.
Inhalation: Causes severe irritation of upper respiratory tract with coughing, burns,
breathing difficulty, and possible coma. May be fatal if exposed to high concentrations.
Aspiration may lead to pulmonary edema. May also cause pallor, loss of appetite, nausea,
vomiting, diarrhea, weakness, darkened urine, headache, sweating, convulsions, cyanosis
(bluish skin due to deficient oxygenation of the blood), unconsciousness, fatigue,
pulmonary edema & coma. Inhalation at high concentrations may cause CNS depression
and asphixiation.
Chronic: Chronic inhalation and ingestion may cause effects similar to those of acute
inhalation and ingestion. May cause reproductive and fetal effects. Effects may be
delayed. Laboratory experiments have resulted in mutagenic effects. Repeated skin
contact may cause dermatitis with dark pigmentation of the skin. Animal studies have
reported the development of tumors. Chronic exposures have been reported to cause
death from liver and kid ney damage.
Section 4 - First Aid Measures
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed.
Extensive irrigation with water is required (at least 30 minutes).
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes. Discard contaminated
clothing in a manner which limits further exposure. SPEEDY ACTION IS CRITICAL!
Destroy contaminated shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. SPEED IS
ESSENTIAL. A DOCTOR MUST BE NOTIFIED AT ONCE.
Inhalation: Remove from exposure and move to fresh air immediately. If breathing is
difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased
apply artificial respiration using oxygen and a suitable mechanical device such as a bag
and a mask. SPEED IS ESSENTIAL, OBTAIN MEDICAL AID IMMEDIATELY.
Notes to Physician: Persons with liver or kidney disease should not be exposed to
phenol for any length of time.
Antidote: Activated charcoal, followed by cathartic, may be preferred to ipecac induced
emesis or lavage in decontamination of the GI tract and preventing systemic absorption
of phenol.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Use water spray to keep fire-exposed containers cool. This
material in sufficient quantity and reduced particle size is capable of creating a dust
explosion. Containers may explode when heated.
Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam. Use water spray to cool fire-exposed containers. Use agent most
appropriate to extinguish fire.
Flash Point: 79 deg C ( 174.20 deg F)
Autoignition Temperature: 605 deg C ( 1,121.00 deg F)
Explosion Limits, Lower:1.7 vol %
Upper: 8.6 vol %
NFPA Rating: (estimated) Health: 4; Flammability: 2; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Avoid generating dusty conditions. Remove all sources of ignition. Use a spark-proof tool.
Provide ventilation.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Minimize dust generation and accumulation. Do not get in eyes, on skin, or
on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be
dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Do
not ingest or inhale. Store protected from light. Use only in a chemical fume hood.
Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or
expose empty containers to heat, sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition.
Keep container closed when not in use. Store in a tightly closed container. Keep from
contact with oxidizing materials. Keep refrigerated. (Store below 4°C/39°F.) Store
protected from moisture. Store protected from light. Elevated temperatures will tend to
oxidize the product and "Fuse" the dry crystals.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility and a safety shower.
Use adequate general or local exhaust ventilation to keep airborne concentrations below
the permissible exposure limits.
Exposure Limits
Chemical Name
Phenol
ACGIH
5 ppm TWA; skin potential for cutaneous
absorption
NIOSH
OSHA - Final PELs
5 ppm TWA; 19 mg/m3
TWA 250 ppm IDLH
5 ppm TWA; 19 mg/m3
TWA
OSHA Vacated PELs: Phenol: 5 ppm TWA; 19 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Solid
Appearance: white
Odor: sweet, fruity odor - sharp odor
pH: 6 aqueous solution
Vapor Pressure: 1 mm Hg @ 40.1 deg C
Vapor Density: 3.2
Evaporation Rate:0.01 (butyl acetate=1)
Viscosity: 12.7 centipoise
Boiling Point: 90.2 deg C @ 25 mmHg
Freezing/Melting Point:43 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:1.07 (water=1)
Molecular Formula:C6H5OH
Molecular Weight:94.0414
Section 10 - Stability and Reactivity
Chemical Stability: Prone to redden on exposure to air and light. Phenol may liquify on
exposure to moist air.
Conditions to Avoid: Light, ignition sources, dust generation, excess heat, exposure to
moist air or water.
Incompatibilities with Other Materials: Strong oxidizing agents, acids, isocyanates,
acetaldehyde, nitrides (e.g. potassium nitride, sodium nitride), calcium hypochlorite,
peroxomonosulfuric acid, nitrobenzene, sodium nitrite, moisture, aluminum chloride,
peroxydisulfuric acid, 1,3-butadiene, boron trifluoride diethyl ether.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 108-95-2: SJ3325000
LD50/LC50:
CAS# 108-95-2:
Draize test, rabbit, eye: 5 mg Severe;
Draize test, rabbit, skin: 500 mg/24H Severe;
Draize test, rabbit, skin: 100 mg Mild;
Inhalation, mouse: LC50 = 177 mg/m3;
Inhalation, rat: LC50 = 316 mg/m3;
Oral, mouse: LD50 = 270 mg/kg;
Oral, rat: LD50 = 317 mg/kg;
Skin, rabbit: LD50 = 630 mg/kg;
Skin, rat: LD50 = 669 mg/kg;
Carcinogenicity:
CAS# 108-95-2:
IARC: IARC Group 3 - not classifiable
Epidemiology: The predominant acute action of a toxic dose of phenol in m an appears
to be to the central nervous system, lead ing to sudden collapse and unconsciousness.
Teratogenicity: Oral, rat: TDLo = 1200 mg/kg (female 6-15 day(s) after conception)
Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus).; Oral,
mouse: TDLo = 4 gm/kg (female 6-15 day(s) after conception) Specific Developmental
Abnormalities - musculoskeletal system.
Reproductive Effects: Oral, rat: TDLo = 300 mg/kg (female 6-15 day(s) after
conception) Fertility - post-implantation mortality (e.g. dead and/or resorbed implants
per total number of implants).
Neurotoxicity: No data available.
Mutagenicity: Mutation Test Systems - not otherwise specified: Human, HeLa cell = 17
mg/L.; DNA Inhibition: Human, HeLa cell = 1 mmol/L.; Mutation Test Systems - not
otherwise specified: Human, Lymphocyte = 5 umol/L.; Sister Chromatid Exchange:
Human, Lymphocyte = 5 umol/L.
Other Studies: Standard Draize Test: Administration onto the skin (rabbit) = 500
mg/24H (Severe). Standard Draize Test: Administra tion into the eye (rabbit) = 5 mg
(Severe).
Section 12 - Ecological Information
Ecotoxicity: Water flea Daphnia: EC50=12 mg/l; 48-hour; CAS# 108-95-2:
UnspecifiedWater flea Daphnia: EC50=4.0 mg/l; 96-hour; CAS# 108-95-2:
UnspecifiedFish: Fathead Minnow: LC50 > 50 mg/l; 1 Hr; CAS# 108-95-2 Static @ 18-22°
CFish: Fathead Minnow: TLm = 41 mg/L; 48-hour; CAS# 108-95-2: Flow-through @ 15°
CFish: Bluegill/Sunfish: TLm = 19 / 5.7 mg/L; 96 Hr; CAS# 108-95-2: Flow-through If
released to the environment, phenol's primary removal mechanism is biodegradation
which is generally rapid (days). If phenol is released to soil, it will readily leach and
biodegrade. The biodegradation in soil is generally rapid with half-lives of under 5 days
even in subsurface soils.
Environmental: Phenol does not bioconcentrate in aquatic organisms. In the
atmosphere, phenol occurs as a vapor and reacts with photochemically-produced
hydroxyl radicals resulting in a half-life of approximately 15 hours. During the nighttime,
it reacts with nitrate radicals with a resulting half-life of 12 minutes. Phenol has also been
shown to be readily removed from the atmosphere by rain.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 108-95-2: waste number U188.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
PHENOL,
SOLID
Hazard Class: 6.1
UN Number:
Canada TDG
PHENOL, SOLID
6.1(9.2)
UN1671
Packing Group: II
UN1671
II
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 108-95-2 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 108-95-2: Effective 6/1/87; Sunset 6/1/97
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
CAS# 108-95-2: Present
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 108-95-2: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
CAS# 108-95-2: 500 lb TPQ (lower threshold); 10000 lb TPQ (upper thres hold)
SARA Codes
CAS # 108-95-2: acute, chronic, flammable.
Section 313
This material contains Phenol (CAS# 108-95-2, 100%),which is subject to the reporting
requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 108-95-2 is listed as a hazardous air pollutant (HAP). This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
CAS# 108-95-2 is listed as a Hazardous Substance under the CWA. CAS# 108-95-2 is
listed as a Priority Pollutant under the Clean Water Act. CAS# 108-95-2 is listed as a
Toxic Pollutant under the Clean Water Act.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 108-95-2 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
T
Risk Phrases:
R 34 Causes burns.
R 24/25 Toxic in contact with skin and if swallowed.
Safety Phrases:
S 28 After contact with skin, wash immediately
with...
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 108-95-2: 2
Canada - DSL/NDSL
CAS# 108-95-2 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D1A, E, D2B.
Canadian Ingredient Disclosure List
CAS# 108-95-2 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 108-95-2: OEL-ARAB Republic of Egypt:TWA 5 ppm (19 mg/m3);Skin
OEL-AUSTRALIA:TWA 5 ppm (19 mg/m3);Skin OEL-BELGIUM:TWA 5 ppm (19 mg
/m3);Skin OEL-CZECHOSLOVAKIA:TWA 20 mg/m3;STEL 40 mg/m3 OEL-DENMARK:
TWA 5 ppm (19 mg/m3);Skin OEL-FINLAND:TWA 5 ppm (19 mg/m3);STEL 10 pp
m (38 mg/m3);Skin OEL-FRANCE:TWA 5 ppm (19 mg/m3);Skin OEL-GERMANY:T
WA 5 ppm (19 mg/m3);Skin OEL-HUNGARY:TWA 4 mg/m3;STEL 8 mg/m3;Skin O
EL-JAPAN:TWA 5 ppm (19 mg/m3);Skin OEL-THE NETHERLANDS:TWA 5 ppm (19
mg/m3);Skin OEL-THE PHILIPPINES:TWA 5 ppm (10 mg/m3);Skin OEL-POLAND
:TWA 10 ppm OEL-RUSSIA:TWA 5 ppm;STEL 0.3 mg/m3;Skin OEL-SWEDEN:TWA
1 ppm (4 mg/m3);STEL 2 ppm (8 mg/m3);Skin OEL-SWITZERLAND:TWA 5 ppm (
19 mg/m3);STEL 10 ppm (38 mg/m3);Skin OEL-THAILAND:TWA 5 ppm (19 mg/m
3) OEL-TURKEY:TWA 5 ppm (19 mg/m3);Skin OEL-UNITED KINGDOM:TWA 5 ppm
(19 mg/m3);STEL 10 ppm;Skin OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA
check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TL
V
Section 16 - Additional Information
MSDS Creation Date: 7/15/1999
Revision #4 Date: 3/18/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
MATERIAL SAFETY DATA SHEET
PODOCON-25
PADDOCK LABORATORIES, INC.
3940 QUEBEC AVENUE NORTH
MINNEAPOLIS, MINNESOTA 55427
PHONE: (763)-546-4676
EMERGENCY ASSISTANCE:
CHEMTREC
800-424-9300
202-483-7616
PADDOCK TECH. ASST. 800-328-5113
SECTION 1 - PRODUCT IDENTIFICATION AND HAZARDOUS COMPONENTS
PRODUCT NAME: Podocon-25
SYNONYMS: 25% Podophyllin in Benzoin Tincture
MOLECULAR FORMULA: Mixture
MOLECULAR WEIGHT: N/A
CHEMICAL NAME: N/A
CHEMICAL FAMILY: Topical wart remover
INGREDIENT (CAS #)
%
Ethanol (64-17-5)
Podophyllin resin
60
25
OSHA PEL
ACGIH TLV
1,000 ppm
N/A
1,000 ppm
N/A
Any unlisted ingredients are not considered hazardous and are present at a concentration of less than 5%.
SECTION 2 - PHYSICAL AND CHEMICAL CHARACTERISTICS
BOILING POINT:
N/A
VAPOR PRESSURE:
MELTING POINT:
N/A
VAPOR DENSITY:
SPECIFIC GRAVITY:
(WATER = 1)
0.93
WATER SOLUBILITY:
Insoluble
N/A
N/A
EVAPORATION RATE:
(BUTYL ACETATE = 1)
WATER REACTIVE:
N/A
No
APPEARANCE AND ODOR: Dark brown, mobile liquid with a characteristic odor.
MSDS - Podocon-25
Page 2 of 4
SECTION 3 - FIRE AND EXPLOSION DATA
FLASH POINT (METHOD):
N/A
AUTOIGNITION TEMPERATURE: N/A
FLAMMABLE LIMITS: LOWER: N/A
UPPER: N/A
EXTINGUISHING MEDIA: Dry chemical, foam or CO2 .
SPECIAL FIRE FIGHTING PROCEDURES: Fire fighters should wear full protective gear including self-contained
breathing apparatus.
UNUSUAL FIRE AND EXPLOSION HAZARDS: As with any organic compound, this material may produce toxic
fumes if heated to decomposition (as under fire conditions).
SECTION 4 - REACTIVITY HAZARD DATA
STABILITY: Stable ( X ) Unstable ( )
INCOMPATIBILITY (MATERIALS TO AVOID): Water.
HAZARDOUS DECOMPOSITION PRODUCTS: As with any organic compound, this material may produce toxic
fumes if heated to decomposition.
HAZARDOUS POLYMERIZATION: May Occur ( ) Will Not Occur ( X )
SECTION 5 - HEALTH HAZARD DATA
TOXICITY:
No specific toxicity data available for this compound, however, the ingredients are toxic if ingested.
Podophyllin resin is a potent cytotoxin.
CARCINOGEN LISTED BY:
NTP
IARC
OSHA
Other
Yes ( )
Yes ( )
Yes ( )
Yes ( )
No ( X )
No ( X )
No ( X )
No ( X )
ROUTES OF ENTRY: Inhalation, ingestion, contact.
SIGNS AND SYMPTOMS OF OVEREXPOSURE:
INHALATION: May cause irritation of the respiratory tract, headache, nausea, dizziness.
EYE CONTACT: May cause slight to severe irritation and tissue damage.
MSDS - Podocon-25
Page 3 of 4
SKIN CONTACT: May cause slight to severe irritation and tissue damage.
INGESTION: May cause slight to severe irritation and tissue damage of the gastrointestinal tract, nausea,
vomiting.
CHRONIC EFFECTS OF OVEREXPOSURE: Dermatitis, destruction of tissues, possible hypersensitization.
MEDICAL CONDITIONS AGGRAVATED BY OVEREXPOSURE: Hypersensitivity to any ingredient in this
material, skin irritation or sensitivity.
OTHER PRECAUTIONS TO CONSIDER: Persons developing hypersensitivity (anaphylactic) reactions must receive
immediate medical attention. Avoid contact with eyes or mucous membranes.
EMERGENCY FIRST AID PROCEDURES:
INHALATION: Remove from exposure. If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. Seek immediate medical attention.
EYE CONTACT: Flush with water for at least 15 minutes and seek immediate medical attention.
SKIN CONTACT: Wash thoroughly with soap and water and seek immediate medical attention.
INGESTION: Flush mouth out with water and seek medical attention or contact a poison control center
immediately.
SECTION 6 - CONTROL AND PROTECTIVE MEASURES
RESPIRATORY PROTECTION: NIOSH/MSHA approved respirator.
PROTECTIVE GLOVES: Rubber.
EYE PROTECTION: Safety glasses or goggles required. Avoid wearing contact lenses when working with this or any
chemical due to the possibility of increased severity of eye damage.
VENTILATION: Local exhaust recommended.
OTHER PROTECTIVE EQUIPMENT: Appropriate laboratory apparel.
HYGIENIC WORK PRACTICES: Do not eat, drink or smoke near this material. Wash thoroughly after handling and
wash any contaminated clothing before reuse.
SECTION 7 - HANDLING AND STORAGE PRECAUTIONS
MSDS - Podocon-25
Page 4 of 4
HANDLING PRECAUTIONS: Avoid contact with eyes, skin or clothing and avoid breathing fumes. Wash
thoroughly after handling and wash any contaminated clothing before reuse.
STORAGE PRECAUTIONS: Store in a tight container in a cool, dry, well ventilated location.
SECTION 8 - SPILL AND DISPOSAL PROCEDURES
STEPS TO BE TAKEN IN CASE OF SPILL OR DISCHARGE: Wear all protective gear including: respirator,
goggles, gloves and apron. Mop up spillage with an absorbent material and place in a tight container. Wash and
ventilate spill site. Wash thoroughly or shower after handling and wash all clothing and protective gear before reuse.
WASTE DISPOSAL METHOD: Dispose of in accordance with all applicable local, state, federal, and environmental
regulations.
SECTION 9 - DISCLAIMER
The information contained in this Material Safety Data Sheet has been compiled from reliable sources and is believed to
be correct as of the date issued. It is the responsibility of the user to determine the appropriateness and applicability to
their situation. Paddock Laboratories, Inc. disclaims any expressed or implied warranty as to the accuracy of the above
information and shall not be held liable for any direct, incidental, or consequential damages from use or reliance on the
above information.
_________________________________________________________________________________________
DEFINITIONS OF ABBREVIATIONS USED:
ACGIH:
CAS:
IARC:
IDLH:
LC50 :
LD50 :
MSHA:
N/A:
NIOSH:
NTP:
OSHA:
PEL:
STEL:
TLV:
TWA:
American Conference of Governmental Industrial Hygienists
Chemical Abstract Service
Internal Agency for Research on Cancer
Immediately Dangerous to Life or Health level
Median Lethal Concentration
Median Lethal Dose
Mine Safety and Health Administration
Not available
National Institute for Occupational Safety and Health
National Toxicology Program
Occupational Safety and Health Administration
Permissible Exposure Limit
Short Term Exposure Limit
Threshold Limit Value
Time Weighted Average
Material Safety Data Sheet
Potassium Hydroxide Solution, 10.0%
ACC# 92255
Section 1 - Chemical Product and Company Identification
MSDS Name: Potassium Hydroxide Solution, 10.0%
Catalog Numbers: AC613250000, AC613255000
Synonyms: None
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
CAS#
Chemical Name
1310-58-3
Potassium hydroxide
7732-18-5
Water
Percent
EINECS/ELINCS
10.0
215-181-3
Balance
231-791-2
Hazard Symbols: C
Risk Phrases: 35
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: clear to slightly turbid liquid. Danger! Corrosive. Causes eye and skin
burns. May cause severe respiratory tract irritation with possible burns. May cause severe
digestive tract irritation with possible burns. May be harmful if swallowed.
Target Organs: Eyes, skin.
Potential Health Effects
Eye: Causes eye burns. Contact may cause ulceration of the conjunctiva and cornea. Eye
damage may be delayed.
Skin: Causes skin burns. May cause deep, penetrating ulcers of the skin. May cause skin
rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
Ingestion: May cause severe and permanent damage to the digestive tract. May cause
circulatory system failure. May cause perforation of the digestive tract. Causes severe
digestive tract burns with abdominal pain, vomiting, and possible death. May be harmful
if swallowed. May cause systemic effects.
Inhalation: Irritation may lead to chemical pneumonitis and pulmonary edema. Causes
severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and
possible coma. Causes chemical burns to the respiratory tract. Aspiration may lead to
pulmonary edema. May cause systemic effects.
Chronic: Prolonged or repeated skin contact may cause dermatitis. Prolonged or
repeated eye contact may cause conjunctivitis. Effects may be delayed.
Section 4 - First Aid Measures
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed.
Extensive irrigation with water is required (at least 30 minutes).
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes. Wash clothing before
reuse. Discard contaminated clothing in a manner which limits further exposure. Destroy
contaminated shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. Get medical aid
immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air
immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth
resuscitation. If breathing has ceased apply artificial respiration using oxygen and a
suitable mechanical device such as a bag and a mask.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Wear appropriate protective clothing to prevent contact
with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact
with thermal decomposition products. Use water with caution and in flooding amounts.
Non-combustible, substance itself does not burn but may decompose upon heating to
produce irritating, corrosive and/or toxic fumes.
Extinguishing Media: Substance is noncombustible; use agent most appropriate to
extinguish surrounding fire. Cool containers with flooding quantities of water until well
after fire is out.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Neutralize spill with a weak acid such as vinegar or acetic
acid. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills
immediately, observing precautions in the Protective Equipment section. Provide
ventilation.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Use only in a well-ventilated area. Do not breathe dust, vapor, mist, or gas.
Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or
inhale. Discard contaminated shoes.
Storage: Keep container closed when not in use. Store in a tightly closed container.
Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away
from strong acids. Corrosives area.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits
Chemical Name
Potassium hydroxide
Water
ACGIH
NIOSH
OSHA - Final PELs
2 mg/m3 Ceiling
none listed
none listed
none listed
none listed
none listed
OSHA Vacated PELs: Potassium hydroxide: No OSHA Vacated PELs are listed for this
chemical. Water: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear to slightly turbid
Odor: odorless
pH: 12.0 (0.1 M sol.)
Vapor Pressure: 2.6 mm Hg @ 20 C
Vapor Density: >1.0
Evaporation Rate:Not available.
Viscosity: 3.7 cP
Boiling Point: 271-293F
Freezing/Melting Point:48 deg F
Decomposition Temperature:Not available.
Solubility: Completely soluble in water
Specific Gravity/Density:1.51
Molecular Formula:Solution
Molecular Weight:Not available.
Section 10 - Stability and Reactivity
Chemical Stability: Stable at room temperature in closed containers under normal
storage and handling conditions.
Conditions to Avoid: Incompatible materials, acids, metals.
Incompatibilities with Other Materials: Strong oxidizing agents, strong acids.
Hazardous Decomposition Products: Irritating and toxic fumes and gases, oxides of
potassium.
Hazardous Polymerization: Has not been reported
Section 11 - Toxicological Information
RTECS#:
CAS# 1310-58-3: TT2100000
CAS# 7732-18-5: ZC0110000
LD50/LC50:
CAS# 1310-58-3:
Draize test, rabbit, skin: 50 mg/24H Severe;
Oral, rat: LD50 = 273 mg/kg;
CAS# 7732-18-5:
Oral, rat: LD50 = >90 mL/kg;
Carcinogenicity:
CAS# 1310-58-3: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 7732-18-5:
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No data available.
Teratogenicity: No data available.
Reproductive Effects: No data available.
Neurotoxicity: No data available.
Mutagenicity: No data available.
Other Studies: See actual entry in RTECS for complete information.
Section 12 - Ecological Information
Ecotoxicity: Fish: Mosquito Fish: LC50 = 80.0 mg/L; 24 Hr.; Unspecified
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
POTASSIUM
HYDROXIDE,
SOLUTION
Hazard Class: 8
UN Number:
UN1814
Packing Group: II
IATA
RID/ADR
IMO
Canada TDG
No information
available.
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 1310-58-3 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 1310-58-3: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 1310-58-3: acute, reactive.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
CAS# 1310-58-3 is listed as a Hazardous Substance under the CWA. None of the
chemicals in this product are listed as Priority Pollutants under the CWA. None of the
chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 1310-58-3 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
C
Risk Phrases:
R 35 Causes severe burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 27 Take off immediately all contaminated clothing.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 1310-58-3: 1
CAS# 7732-18-5: No information available.
Canada - DSL/NDSL
CAS# 1310-58-3 is listed on Canada's DSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
Canada - WHMIS
WHMIS: Not available.
Canadian Ingredient Disclosure List
CAS# 1310-58-3 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 1310-58-3: OEL-AUSTRALIA:TWA 2 mg/m3 OEL-BELGIUM:STEL 2 mg/m3
OEL-DENMARK:TWA 2 mg/m3 OEL-FINLAND:TWA 2 mg/m3 OEL-FRANCE:STEL 2 m
g/m3 OEL-JAPAN:STEL 2 mg/m3 OEL-THE NETHERLANDS:TWA 2 mg/m3 OEL-SWI
TZERLAND:TWA 2 mg/m3 OEL-UNITED KINGDOM:TWA 2 mg/m3;STEL 2 mg/m3 OEL
IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEAL
AND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 1/18/2002
Revision #1 Date: 1/18/2002
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Propylene glycol
ACC# 19870
Section 1 - Chemical Product and Company Identification
MSDS Name: Propylene glycol
Catalog Numbers: S80150, BPP355-200LC, P355-1, P355-20, P355-200, P355-4,
P355200LC, S80150-1
Synonyms: 1,2-Dihydroxypropane; Methylethylene glycol; Monopropylene glycol; 1,2Propylene glycol; 1,2-Propanediol; 2-Hydroxypropanol.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
57-55-6
Chemical Name
Propylene glycol
Percent
EINECS/ELINCS
100
200-338-0
Hazard Symbols: None listed.
Risk Phrases: None listed.
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless viscous liquid. Hygroscopic (absorbs moisture from the air).
Caution! May cause eye, skin, and respiratory tract irritation.
Target Organs: Central nervous system.
Potential Health Effects
Eye: May cause slight transient injury.
Skin: May be absorbed through damaged or abraded skin in harmful amounts. Allergic
reactions have been reported. A single prolonged skin exposure is not likely to result in
the material being absorbed in harmful amounts. Prolonged contact is essentially nonirritating to skin. Repeated exposures may cause problems. Propylene glycol causes
allergic contact dermatitis in up to 12.5% of tested individuals.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Low
hazard for usual industrial handling. May cause hemoglobinuric nephrosis. May cause
changes in surface EEG.
Inhalation: Low hazard for usual industrial handling. May cause respiratory tract
irritation. Inhalation of a mist of this material may cause respiratory tract irritation.
Material has a low vapor pressure, so exposure to vapor is not likely.
Chronic: Exposure to large doses may cause central nervous system depression. Chronic
ingestion may cause lactic acidosis and possible seizures. Exposures to propylene glycol
having no adverse effects on the mother should have no effect on the fetus. Birth defects
are unlikely. In animal studies, propylene glycol has been shown not to interfere with
reproduction.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid.
Skin: In case of contact, flush skin with plenty of water. Remove contaminated clothing
and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion: If swallowed, do not induce vomiting unless directed to do so by medical
personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Persons with impaired kidney function may be more susceptible to
the effects of this substance. Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or alcoholresistant foam.
Flash Point: 99 deg C ( 210.20 deg F)
Autoignition Temperature: 371 deg C ( 699.80 deg F)
Explosion Limits, Lower:2.6 vol %
Upper: 12.6 vol %
NFPA Rating: (estimated) Health: 0; Flammability: 1; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Provide ventilation.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing.
Keep container tightly closed. Avoid ingestion and inhalation.
Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area
away from incompatible substances. Store protected from moisture.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits
Chemical Name
Propylene glycol
ACGIH
none listed
NIOSH
OSHA - Final PELs
none listed
none listed
OSHA Vacated PELs: Propylene glycol: No OSHA Vacated PELs are listed for this
chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: colorless viscous
Odor: Odorless
pH: Not available.
Vapor Pressure: 0.08 mm Hg @ 20 deg C
Vapor Density: 2.62 (air=1)
Evaporation Rate:Not available.
Viscosity: 0.581 cps @ 20 deg C
Boiling Point: 187 deg C
Freezing/Melting Point:-60 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:1.0360 g/cm3
Molecular Formula:C3H8O2
Molecular Weight:76.09
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures. Hygroscopic:
absorbs moisture or water from the air.
Conditions to Avoid: Excess heat, moist air.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, aldehydes.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 57-55-6: TY2000000
LD50/LC50:
CAS# 57-55-6:
Draize test, rabbit, eye: 100 mg Mild;
Draize test, rabbit, eye: 500 mg/24H Mild;
Oral, mouse: LD50 = 22 gm/kg;
Oral, mouse: LD50 = 20300 mg/kg;
Oral, rabbit: LD50 = 18500 mg/kg;
Oral, rat: LD50 = 20 gm/kg;
Skin, rabbit: LD50 = 20800 mg/kg;
Skin, rabbit: LD50 = 20800 mg/kg;
Carcinogenicity:
CAS# 57-55-6: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: An expert panel convened by the NTP's Center for the Evaluation of
Risks to Human Reproduction concluded 2/13/03 that developmental and reproductive
risks stemming from exposure to the chemicals propylene glycol and ethylene glycol are
negligible.
Reproductive Effects: When propylene glycol was given at 30 percent in the diet, it
affected reproduction in rates in rats. It has generally not affected fertility or
reproduction, except at very high doses where effects could be attributed to nutritional
deficiency.
Neurotoxicity: No information available.
Mutagenicity: DNA Inhibition: Subcutaneous, mouse = 8000 mg/kg.; Cytogenetic
Analysis: Subcutaneous, mouse = 8000 mg/kg.; Cytogenetic Analysis: Hamster,
Fibroblast = 32 gm/L.
Other Studies: Standard Draize Test: Administration into the eye (rabbit) = 100 mg
(Mild). Standard Draize Test: Administration into the eye (rabbit) = 500 mg/24H (Mild).
Standard Draize Test: Administration onto the skin (human) = 500 mg/7days (Mild).
Standard Draize Test: Administration onto the skin (human ) = 104 mg/3 daysIntermittent (Moderate).
Section 12 - Ecological Information
Ecotoxicity: Water flea Daphnia: EC50 > 10000 mg/L; 48 Hr; UnspecifiedBacteria:
Phytobacterium phosphoreum: EC50 = 710 mg/L; 30 min; Microtox testFish: Goldfish:
LC50 > 5000 mg/L; 24 Hr; UnspecifiedFish: Guppy: LC50 > 1000 mg/L; 48 Hr;
Unspecified If released to water, 1,2-propanediol is expected to degrade relatively rapidly
via biodegradation. If released to soil, relatively rapid biodegradation should also occur.
Significant leaching in soil can be predicted.
Environmental: If released to the atmosphere, it is degraded rapidly by reaction with
photochemically produced hydroxyl radicals (typical half-life of 32 hr). Physical removal
from air by rainfall is possible.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
No
information
available.
Canada TDG
No information
available.
Hazard Class:
UN Number:
Packing Group:
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 57-55-6 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 57-55-6 can be found on the following state right to know lists: Pennsylvania,
Minnesota.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 57-55-6: 0
Canada - DSL/NDSL
CAS# 57-55-6 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of Not controlled..
Canadian Ingredient Disclosure List
CAS# 57-55-6 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
Section 16 - Additional Information
MSDS Creation Date: 5/27/1999
Revision #3 Date: 12/10/2002
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Reagent Alcohol
ACC# 92311
Section 1 - Chemical Product and Company Identification
MSDS Name: Reagent Alcohol
Catalog Numbers: AC613180000, AC613180010
Synonyms: Ethyl Alcohol; Ethyl Hydrate; Ethyl Hydroxide; Fermentation Alcohol; Grain
Alcohol; Methylcarbinol; Molasses Alcohol; Spirits of Wine.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
CAS#
64-17-5
7732-18-5
Chemical Name
Ethyl alcohol
Water
Percent
EINECS/ELINCS
70.0
200-578-6
Balance
231-791-2
Hazard Symbols: F
Risk Phrases: 11
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless clear liquid. Flash Point: 16.6 deg C. Flammable liquid and
vapor. May cause central nervous system depression. Causes severe eye irritation.
Causes respiratory tract irritation. May cause digestive tract irritation. Causes moderate
skin irritation. This substance has caused adverse reproductive and fetal effects in
humans. Warning! May cause liver, kidney and heart damage.
Target Organs: Kidneys, heart, central nervous system, liver.
Potential Health Effects
Eye: Causes severe eye irritation. May cause painful sensitization to light. May cause
chemical conjunctivitis and corneal damage.
Skin: Causes moderate skin irritation. May cause cyanosis of the extremities.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May
cause systemic toxicity with acidosis. May cause central nervous system depression,
characterized by excitement, followed by headache, dizziness, drowsiness, and nausea.
Advanced stages may cause collapse, unconsciousness, coma and possible death due to
respiratory failure.
Inhalation: Inhalation of high concentrations may cause central nervous system effects
characterized by nausea, headache, dizziness, unconsciousness and coma. Causes
respiratory tract irritation. May cause narcotic effects in high concentration. Vapors may
cause dizziness or suffocation.
Chronic: May cause reproductive and fetal effects. Laboratory experiments have resulted
in mutagenic effects. Animal studies have reported the development of tumors. Prolonged
exposure may cause liver, kidney, and heart damage.
Section 4 - First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid. Gently lift eyelids and flush
continuously with water.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Wash clothing before reuse. Flush skin with
plenty of soap and water.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT
use mouth-to-mouth resuscitation.
Notes to Physician: Treat symptomatically and supportively. Persons with skin or eye
disorders or liver, kidney, chronic respiratory diseases, or central and peripheral nervous
sytem diseases may be at increased risk from exposure to this substance.
Antidote: Replace fluid and electrolytes.
Section 5 - Fire Fighting Measures
General Information: Containers can build up pressure if exposed to heat and/or fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/
NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive
mixture with air. Vapors can travel to a source of ignition and flash back. Will burn if
involved in a fire. Flammable Liquid. Can release vapors that form explosive mixtures at
temperatures above the flashpoint. Use water spray to keep fire-exposed containers cool.
Containers may explode in the heat of a fire.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam.
Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use
straight streams of water.
Flash Point: 16.6 deg C ( 61.88 deg F)
Autoignition Temperature: 363 deg C ( 685.40 deg F)
Explosion Limits, Lower:3.3 vol %
Upper: 19.0 vol %
NFPA Rating: (estimated) Health: 2; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Remove all sources of ignition. Use a spark-proof tool. Provide
ventilation. A vapor suppressing foam may be used to reduce vapors.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Use only in a well-ventilated area. Ground
and bond containers when transferring material. Use spark-proof tools and explosion
proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain
product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly
closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not
pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat,
sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition.
Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a
cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Do
not store near perchlorates, peroxides, chromic acid or nitric acid.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility and a safety shower.
Use adequate general or local exhaust ventilation to keep airborne concentrations below
the permissible exposure limits.
Exposure Limits
Chemical Name
ACGIH
NIOSH
OSHA - Final PELs
Ethyl alcohol
Water
1000 ppm TWA
none listed
1000 ppm TWA; 1900
mg/m3 TWA 3300 ppm
IDLH
1000 ppm TWA; 1900
mg/m3 TWA
none listed
none listed
OSHA Vacated PELs: Ethyl alcohol: 1000 ppm TWA; 1900 mg/m3 TWA Water: No
OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Clear liquid
Appearance: colorless
Odor: Mild, rather pleasant, like wine or whis
pH: Not available.
Vapor Pressure: 59.3 mm Hg @ 20 deg C
Vapor Density: 1.59
Evaporation Rate:Not available.
Viscosity: 1.200 cP @ 20 deg C
Boiling Point: 78 deg C
Freezing/Melting Point:-114.1 deg C
Decomposition Temperature:Not available.
Solubility: Miscible.
Specific Gravity/Density:0.790 @ 20°C
Molecular Formula:C2H5OH
Molecular Weight:46.0414
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, ignition sources, excess heat, oxidizers.
Incompatibilities with Other Materials: Strong oxidizing agents, acids, alkali metals,
ammonia, hydrazine, peroxides, sodium, acid anhydrides, calcium hypochlorite, chromyl
chloride, nitrosyl perchlorate, bromine pentafluoride, perchloric acid, silver nitrate,
mercuric nitrate, potassium-tert-butoxide, magnesium perchlorate, acid chlorides,
platinum, uranium hexafluoride, silver oxide, iodine heptafluoride, acetyl bromide,
disulfuryl difluoride, tetrachlorosilane + water, acetyl chloride, permanganic acid,
ruthenium (VIII) oxide, uranyl perchlorate, potassium dioxide.
Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 64-17-5: KQ6300000
CAS# 7732-18-5: ZC0110000
LD50/LC50:
CAS# 64-17-5:
Draize test, rabbit, eye: 500 mg Severe;
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, skin: 20 mg/24H Moderate;
Inhalation, mouse: LC50 = 39 gm/m3/4H;
Inhalation, rat: LC50 = 20000 ppm/10H;
Oral, mouse: LD50 = 3450 mg/kg;
Oral, rabbit: LD50 = 6300 mg/kg;
Oral, rat: LD50 = 7060 mg/kg;
Oral, rat: LD50 = 9000 mg/kg;
CAS# 7732-18-5:
Oral, rat: LD50 = >90 mL/kg;
Carcinogenicity:
CAS# 64-17-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 7732-18-5: Not
listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: Ethanol has been shown to produce fetotoxicity in the embry o or fetus
of laboratory animals. Prenatal exposure to ethanol is associated with a distinct pattern of
co ngenital malformations that have collecetively been termed the "fetal alcohol
syndrome".
Teratogenicity: Oral, Human - woman: TDLo = 41 gm/kg (female 41 week(s) after
conception) Effects on Newborn - Apgar score (human only) and Effects on Newborn other neonatal measures or effects and Effects on Newborn - drug dependence.
Reproductive Effects: Intrauterine, Human - woman: TDLo = 200 mg/kg (female 5 day
(s) pre-mating) Fertility - female fertility index (e.g. # females pregnant per # sperm
positive females; # females pregnant per # females mated).
Neurotoxicity: No information available.
Mutagenicity: DNA Inhibition: Human, Lymphocyte = 220 mmol/L.; Cytogenetic
Analysis: Human, Lymphocyte = 1160 gm/L.; Cytogenetic Analysis: Human, Fibroblast =
12000 ppm.; Cytogenetic Analysis: Human, Leukocyte = 1 pph/72H (Continuous).; Sister
Chromatid Exchange: Human, Lymphocyte = 500 ppm/72H (Continuous).
Other Studies: Standard Draize Test(Skin, rabbit) = 20 mg/24H (Moderate) S tandard
Draize Test: Administration into the eye (rabbit) = 500 mg (Severe).
Section 12 - Ecological Information
Ecotoxicity: Fish: Rainbow trout: LC50 = 12900-15300 mg/L; 96 Hr; Flow-through @
24-24.3°CFish: Rainbow trout: LC50 = 11200 mg/L; 24 Hr; Fingerling (Unspecified)
Bacteria: Phytobacterium phosphoreum: EC50 = 34900 mg/L; 5-30 min; Microtox test
When spilled on land it is apt to volatilize, biodegrade, and leach into the ground water,
but no data on the rates of these processes could be found. Its fate in ground water is
unknown. When released into water it will volatilize and probably biodegrade. It would
not be expected to adsorb to sediment or bioconcentrate in fish.
Environmental: When released to the atmosphere it will photodegrade in hours
(polluted urban atmosphere) to an estimated range of 4 to 6 days in less polluted areas.
Rainout should be significant.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
ETHANOL
SOLUTION
Hazard Class: 3
UN Number:
UN1170
Packing Group: III
Section 15 - Regulatory Information
US FEDERAL
Canada TDG
No information
available.
TSCA
CAS# 64-17-5 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 64-17-5: acute, chronic, flammable.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 64-17-5 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
WARNING: This product contains Ethyl alcohol, a chemical known to the state of
California to cause birth defects or other reproductive harm. California No Significant Risk
Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
F
Risk Phrases:
R 11 Highly flammable.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 33 Take precautionary measures against static
discharges.
S 7 Keep container tightly closed.
S 9 Keep container in a well-ventilated place.
WGK (Water Danger/Protection)
CAS# 64-17-5: 0
CAS# 7732-18-5: No information available.
Canada - DSL/NDSL
CAS# 64-17-5 is listed on Canada's DSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2B, D2A.
Canadian Ingredient Disclosure List
CAS# 64-17-5 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 64-17-5: OEL-AUSTRALIA:TWA 1000 ppm (1900 mg/m3) OEL-BELGIUM:T
WA 1000 ppm (1880 mg/m3) OEL-CZECHOSLOVAKIA:TWA 1000 mg/m3;STEL 5000
mg/m3 OEL-DENMARK:TWA 1000 ppm (1900 mg/m3) OEL-FINLAND:TWA 1000 ppm
(1900 mg/m3);STEL 1250 ppm (2400 mg/m3) OEL-FRANCE:TWA 1000 ppm (190
0 mg/m3);STEL 5000 pp OEL-GERMANY:TWA 1000 ppm (1900 mg/m3) OEL-HUNG
ARY:TWA 1000 mg/m3;STEL 3000 mg/m3 OEL-THE NETHERLANDS:TWA 1000 ppm (
1900 mg/m3) OEL-THE PHILIPPINES:TWA 1000 ppm (1900 mg/m3) OEL-POLAND
:TWA 1000 mg/m3 OEL-RUSSIA:STEL 1000 mg/m3 OEL-SWEDEN:TWA 1000 ppm (
1900 mg/m3) OEL-SWITZERLAND:TWA 1000 ppm (1900 mg/m3) OEL-THAILAND:T
WA 1000 ppm (1900 mg/m3) OEL-TURKEY:TWA 1000 ppm (1900 mg/m3) OEL-UN
ITED KINGDOM:TWA 1000 ppm (1900 mg/m3) JAN9 OEL IN BULGARIA, COLOMBIA
, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNA
M check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 2/25/2002
Revision #1 Date: 2/25/2002
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
MSDS Number: R3900 * * * * * Effective Date: 02/18/03 * * * * * Supercedes: 04/04/00
RESORCINOL
1. Product Identification
Synonyms: Resorcin; 1-3 Dihydroxybenzene; m-Benzenediol; 1,3-Benzenediol
CAS No.: 108-46-3
Molecular Weight: 110.11
Chemical Formula: C6H6O2
Product Codes:
J.T. Baker: 3360, 3366, 3368
Mallinckrodt: 7232
2. Composition/Information on Ingredients
Ingredient
Hazardous
-----------------------------------------------
CAS No
Percent
------------
------------
Resorcinol
Yes
108-46-3
3. Hazards Identification
90 - 100%
Emergency Overview
-------------------------DANGER! MAY BE FATAL IF SWALLOWED. HARMFUL IF INHALED OR ABSORBED
THROUGH SKIN. MAY CAUSE METHEMOGLOBINEMIA. AFFECTS CARDIOVASCULAR
SYSTEM, CENTRAL NERVOUS SYSTEM, BLOOD, SPLEEN, LIVER AND KIDNEYS. CAUSES
SEVERE IRRITATION TO SKIN AND EYES. CAUSES IRRITATION TO RESPIRATORY TRACT.
MAY CAUSE ALLERGIC SKIN REACTION.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
----------------------------------------------------------------------------------------------------------Health Rating: 2 - Moderate
Flammability Rating: 1 - Slight
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES
Storage Color Code: Orange (General Storage)
----------------------------------------------------------------------------------------------------------Potential Health Effects
---------------------------------Inhalation:
Inhalation of dust causes irritation to respiratory tract. Toxic effects may follow and include
methemoglobinemia, convulsions, and death.
Ingestion:
Toxic! A poison to blood and nerves. Causes gastrointestinal upset with severe diarrhea, sweating, weakness,
headache, dizziness, cyanosis, spleen damage, kidney damage, cardiovascular effects, liver damage, and
possibly convulsions and death.
Skin Contact:
Strong irritant to skin, causing severe dermatitis and loss of superficial layers of skin. Can be absorbed through
skin with severe exposures producing symptoms paralleling ingestion and enlargement of local lymph glands.
May cause allergic skin reactions.
Eye Contact:
Strong irritant. Can cause permanent damage.
Chronic Exposure:
Target organs include liver and kidneys.
Aggravation of Pre-existing Conditions:
Persons with pre-existing disorders of the blood, skin, liver, kidneys or lungs may be at an increased risk from
exposure.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention immediately.
Ingestion:
If swallowed, give large quantities of water to drink and get medical attention immediately. Never give
anything by mouth to an unconscious person.
Skin Contact:
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated
clothing and shoes. Get medical attention, immediately. Wash clothing before reuse. Thoroughly clean shoes
before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids
occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Fire:
Flash point: 127C (261F) CC
Autoignition temperature: 608C (1126F)
As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.
Explosion:
Not considered to be an explosion hazard.
Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide. Water spray may be used to keep fire exposed
containers cool.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus
with full facepiece operated in the pressure demand or other positive pressure mode. Sealed containers may
rupture when heated.
6. Accidental Release Measures
Remove all sources of ignition. Ventilate area of leak or spill. Wear appropriate personal protective equipment
as specified in Section 8. Spills: Clean up spills in a manner that does not disperse dust into the air. Use nonsparking tools and equipment. Reduce airborne dust and prevent scattering by moistening with water. Pick up
spill for recovery or disposal and place in a closed container. US Regulations (CERCLA) require reporting
spills and releases to soil, water and air in excess of reportable quantities. The toll free number for the US Coast
Guard National Response Center is (800) 424-8802.
7. Handling and Storage
Keep in a tightly closed container. Store in a cool, dry, ventilated area away from sources of heat or ignition.
Protect against physical damage. Store separately from reactive or combustible materials, and out of direct
sunlight. Isolate from incompatible substances. Control ignition sources. Employ grounding, bonding, venting
and explosion relief provisions in accord with accepted engineering practices in any process capable of
generating an explosion due to static discharge. Containers of this material may be hazardous when empty since
they retain product residues (dust, solids); observe all warnings and precautions listed for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
-ACGIH Threshold Limit Value (TLV):
10 ppm (TWA), 20 ppm (STEL)
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne
Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the
contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH
document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible, a full facepiece particulate respirator
(NIOSH type N100 filters) may be worn for up to 50 times the exposure limit or the maximum use
concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. If oil
particles (e.g. lubricants, cutting fluids. glycerine, etc.) are present, use a NIOSH type R or P filter. For
emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, airsupplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient
atmospheres. If heat is involved, an organic vapor/particulate cartridge (NIOSH type N95 or better filter) may
be necessary.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to
prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible.
Maintain eye wash fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
White powder or crystals. May have pinkish cast.
Odor:
Slight characteristic odor.
Solubility:
Completely soluble in water.
Specific Gravity:
1.27
pH:
5.2
% Volatiles by volume @ 21C (70F):
No information found.
Boiling Point:
280C (536F)
Melting Point:
110C (230F)
Vapor Density (Air=1):
3.8
Vapor Pressure (mm Hg):
1 @ 42C (108F)
Evaporation Rate (BuAc=1):
No information found.
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage. Discolors on exposure to air and light (turns pink).
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Oxidizers, alkalis, ferric salts, acetanilide, albumin, alkalis, antipyrine, ferric salts, camphor, menthol, spirit
nitrous ether, and urethane.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
11. Toxicological Information
Investigated as a tumorigen and mutagen. Eye rabbit, standard Draize: 100 mg severe; oral rat LD50: 301 mg/
kg; skin rabbit LD50: 3360 mg/kg.
--------\Cancer Lists\--------------------------------------------------------NTP Carcinogen--Ingredient
Known
Anticipated
IARC Category
-------------------------------------------------------------Resorcinol (108-46-3)
No
No
3
12. Ecological Information
Environmental Fate:
When released into the soil, this material is expected to readily biodegrade. When released into the soil, this
material may leach into groundwater. When released into water, this material is expected to readily biodegrade.
This material has an estimated bioconcentration factor (BCF) of less than 100. This material is not expected to
significantly bioaccumulate. When released into the air, this material is expected to be readily degraded by
reaction with photochemically produced hydroxyl radicals. When released into the air, this material is expected
to have a half-life of less than 1 day.
Environmental Toxicity:
This material is expected to be slightly toxic to aquatic life. The LC50/96-hour values for fish are between 10
and 100 mg/l.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to a RCRA
approved waste facility. Processing, use or contamination of this product may change the waste management
options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container
and unused contents in accordance with federal, state and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
----------------------Proper Shipping Name: RESORCINOL
Hazard Class: 6.1
UN/NA: UN2876
Packing Group: III
Information reported for product/size: 12KG
International (Water, I.M.O.)
----------------------------Proper Shipping Name: RESORCINOL
Hazard Class: 6.1
UN/NA: UN2876
Packing Group: III
Information reported for product/size: 12KG
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\--------------------------------Ingredient
TSCA EC
Japan Australia
----------------------------------------------- ---- --- ----- --------Resorcinol (108-46-3)
Yes Yes
Yes
Yes
--------\Chemical Inventory Status - Part 2\----------------------------------Canada-Ingredient
Korea DSL
NDSL Phil.
----------------------------------------------- ----- ------ ----Resorcinol (108-46-3)
Yes
Yes
No
Yes
--------\Federal, State & International Regulations - Part 1\----------------SARA 302------SARA 313-----Ingredient
RQ
TPQ
List Chemical Catg.
----------------------------------------- ---------- -------------Resorcinol (108-46-3)
No
No
No
No
--------\Federal, State & International Regulations - Part 2\----------------RCRA-TSCAIngredient
CERCLA
261.33
8(d)
----------------------------------------Resorcinol (108-46-3)
-----5000
Chemical Weapons Convention: No
TSCA 12(b): No
SARA 311/312: Acute: Yes
Chronic: Yes Fire: No
Reactivity: No
(Pure / Solid)
-----U201
-----No
CDTA: No
Pressure: No
Australian Hazchem Code: 2X
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR)
and the MSDS contains all of the information required by the CPR.
16. Other Information
NFPA Ratings: Health: 3 Flammability: 1 Reactivity: 0
Label Hazard Warning:
DANGER! MAY BE FATAL IF SWALLOWED. HARMFUL IF INHALED OR ABSORBED THROUGH
SKIN. MAY CAUSE METHEMOGLOBINEMIA. AFFECTS CARDIOVASCULAR SYSTEM, CENTRAL
NERVOUS SYSTEM, BLOOD, SPLEEN, LIVER AND KIDNEYS. CAUSES SEVERE IRRITATION TO
SKIN AND EYES. CAUSES IRRITATION TO RESPIRATORY TRACT. MAY CAUSE ALLERGIC SKIN
REACTION.
Label Precautions:
Do not get in eyes.
Do not breathe dust.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Label First Aid:
If swallowed, give large amounts of water to drink. Never give anything by mouth to an unconscious person. If
inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. In
case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes. Remove
contaminated clothing and shoes. Wash clothing before reuse. In all cases get medical attention immediately.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 8.
Disclaimer:
************************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no
representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the
appropriate precautionary handling of the material by a properly trained person using this product.
Individuals receiving the information must exercise their independent judgment in determining its
appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO
REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING
WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR
THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT
BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR
RELIANCE UPON THIS INFORMATION.
************************************************************************************************
Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)
Material Safety Data Sheet
Silver nitrate
ACC# 20810
Section 1 - Chemical Product and Company Identification
MSDS Name: Silver nitrate
Catalog Numbers: S73068, S73069, S78171, S781711, S78172, S78173, BP2546-100,
BP2546-25, BP2546-500, NC9782312, NC9888934, S181-100, S181-25, S181-500,
S181-500LC, S486-100, S486-500
Synonyms: Nitric acid, silver salt.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
7761-88-8
Chemical Name
Silver nitrate
Percent
EINECS/ELINCS
>99.7
231-853-9
Hazard Symbols: O C N
Risk Phrases: 34 8
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless or white solid. Danger! Strong oxidizer. Contact with other
material may cause a fire. Corrosive. Causes eye and skin burns. May cause severe
respiratory tract irritation with possible burns. May cause severe digestive tract irritation
with possible burns. Blue-gray permanent discoloration of the skin, conjunctiva, and
internal organs, known as argyria or argyrosis, results from chronic exposure to silver or
silver salts.
Target Organs: Eyes, skin, mucous membranes.
Potential Health Effects
Eye: Causes eye burns. May cause chemical conjunctivitis and corneal damage.
Skin: Causes skin burns. May be absorbed through the skin.
Ingestion: Causes gastrointestinal tract burns. May cause systemic effects. Lethal dose
for humans is 2 grams.
Inhalation: Causes severe irritation of upper respiratory tract with coughing, burns,
breathing difficulty, and possible coma. May cause systemic effects.
Chronic: May cause methemoglobinemia, which is characterized by chocolate-brown
colored blood, headache, weakness, dizziness, breath shortness, cyanosis (bluish skin
due to deficient oxygenation of blood), rapid heart rate, unconsciousness and possible
death. Chronic inhalation or ingestion of silver salts may cause argyria characterized by a
permanent blue-gray discoloration of the eyes, skin, mucous membranes, and internal
organs. This malady results from the accumulation of silver in the body.
Section 4 - First Aid Measures
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed.
Extensive irrigation with water is required (at least 30 minutes).
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes. Wash clothing before
reuse. Destroy contaminated shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. Get medical aid
immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air
immediately. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply
artificial respiration using oxygen and a suitable mechanical device such as a bag and a
mask.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Strong oxidizer. Contact with combustible materials may cause a fire. During a fire,
irritating and highly toxic gases may be generated by thermal decomposition or
combustion. Wear appropriate protective clothing to prevent contact with skin and eyes.
Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal
decomposition products.
Extinguishing Media: Substance is noncombustible; use agent most appropriate to
extinguish surrounding fire.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 0; Instability: 1; Special Hazard: OX
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation. Do
not use combustible materials such as paper towels to clean up spill.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Minimize dust generation and accumulation.
Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or
inhale. Use with adequate ventilation. Do not store near combustible materials. Discard
contaminated shoes.
Storage: Keep away from sources of ignition. Do not store near combustible materials.
Keep container closed when not in use. Store in a tightly closed container. Store in a
cool, dry, well-ventilated area away from incompatible substances. Corrosives area.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name
Silver nitrate
ACGIH
none listed
NIOSH
OSHA - Final PELs
none listed
none listed
OSHA Vacated PELs: Silver nitrate: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Solid
Appearance: colorless or white
Odor: odorless
pH: ~ 6 (aq soln)
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 433 deg C
Freezing/Melting Point:212 deg C
Decomposition Temperature:440 deg C
Solubility: Soluble.
Specific Gravity/Density:4.35
Molecular Formula:AgNO3
Molecular Weight:169.87
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Heating to decomposition.
Incompatibilities with Other Materials: Strong reducing agents, strong bases,
alcohols, ammonia, hydrogen peroxide, acetylene, charcoal.
Hazardous Decomposition Products: Nitrogen oxides, oxygen.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 7761-88-8: VW4725000
LD50/LC50:
CAS# 7761-88-8:
Draize test, rabbit, eye: 1 mg Severe;
Draize test, rabbit, eye: 10 mg Moderate;
Oral, mouse: LD50 = 50 mg/kg;
Oral, rat: LD50 = 1173 mg/kg;
Carcinogenicity:
CAS# 7761-88-8: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: See actual entry in RTECS for complete information.
Section 12 - Ecological Information
No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
SILVER
NITRATE
Hazard Class: 5.1
UN Number:
UN1493
UN1493
II
Section 15 - Regulatory Information
TSCA
SILVER NITRATE
5.1(9.2)
Packing Group: II
US FEDERAL
Canada TDG
CAS# 7761-88-8 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 7761-88-8: 1 lb final RQ; 0.454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 7761-88-8: acute, chronic, flammable.
Section 313
This material contains Silver nitrate (listed as Silver compounds), 99 7%, (CAS# 776188-8) which is subject to the reporting requirements of Section 313 of SARA Title III and
40 CFR Part 373.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
CAS# 7761-88-8 is listed as a Hazardous Substance under the CWA. None of the
chemicals in this product are listed as Priority Pollutants under the CWA. None of the
chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 7761-88-8 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
OCN
Risk Phrases:
R 34 Causes burns.
R 8 Contact with combustible material may cause
fire.
R 50/53 Very toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 60 This material and its container must be
disposed of as hazardous waste.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 7761-88-8: 3
Canada - DSL/NDSL
CAS# 7761-88-8 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of C, D1A, E.
Canadian Ingredient Disclosure List
CAS# 7761-88-8 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 7761-88-8: OEL-ARAB Republic of Egypt:TWA 0.01 mg(Ag)/m3 OEL-A
USTRALIA:TWA 0.01 mg(Ag)/m3 OEL-BELGIUM:TWA 0.01 mg(Ag)/m3 OEL-DENMA
RK:TWA 0.01 mg(Ag)/m3 OEL-FINLAND:TWA 0.01 mg(Ag)/m3;STEL 0.03 mg(Ag)
/m3;Skin OEL-THE NETHERLANDS:TWA 0.01 mg(Ag)/m3 OEL-THE PHILIPPINES:
TWA 0.01 mg(Ag)/m3 OEL-SWITZERLAND:TWA 0.01 mg(Ag)/m3 OEL-UNITED KIN
GDOM:TWA 0.01 mg(Ag)/m3 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA chec
k ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 5/17/1999
Revision #6 Date: 12/18/2001
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Sodium Benzoate
ACC# 20965
Section 1 - Chemical Product and Company Identification
MSDS Name: Sodium Benzoate
Catalog Numbers: S80174, NC9954256, S224-500, S76783
Synonyms: Benzoic acid, sodium salt; Sodium benzoate.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
532-32-1
Chemical Name
Sodium benzoate
Percent
EINECS/ELINCS
100
208-534-8
Hazard Symbols: None listed.
Risk Phrases: None listed.
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: white crystalline powder. Caution! May cause eye and skin irritation.
Hygroscopic (absorbs moisture from the air). May cause respiratory tract irritation.
Target Organs: None.
Potential Health Effects
Eye: May cause eye irritation. Dust may cause mechanical irritation.
Skin: May cause mild skin irritation.
Ingestion: Ingestion of large amounts may cause gastrointestinal irritation. The
toxicological properties of this substance have not been fully investigated.
Inhalation: May cause respiratory tract irritation. The toxicological properties of this
substance have not been fully investigated.
Chronic: Adverse reproductive effects have been reported in animals. Repeated or
prolonged exposure may cause allergic reactions in sensitive individuals. Repeated
ingestion of benzoates can cause a food allergy.
Section 4 - First Aid Measures
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the
upper and lower eyelids. Get medical aid immediately.
Skin: Flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give
anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.
Antidote: None reported.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. This material in sufficient quantity and reduced particle
size is capable of creating a dust explosion.
Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 1; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Avoid generating dusty conditions. Provide ventilation.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust
generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container
tightly closed. Avoid ingestion and inhalation.
Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area
away from incompatible substances.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name
Sodium benzoate
ACGIH
none listed
NIOSH
OSHA - Final PELs
none listed
none listed
OSHA Vacated PELs: Sodium benzoate: No OSHA Vacated PELs are listed for this
chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or
European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved
respirator when necessary.
Section 9 - Physical and Chemical Properties
Physical State: Crystalline powder
Appearance: white
Odor: odorless
pH: ~ 8 (in aqueous soln)
Vapor Pressure: Negligible.
Vapor Density: Not available.
Evaporation Rate:negligible
Viscosity: Not applicable.
Boiling Point: Not applicable.
Freezing/Melting Point:> 300 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:Not available.
Molecular Formula:C7H5O2Na
Molecular Weight:144.11
Section 10 - Stability and Reactivity
Chemical Stability: Stable. Stable under normal temperatures and pressures.
Conditions to Avoid: Dust generation, exposure to moist air or water.
Incompatibilities with Other Materials: Strong oxidizing agents, acids, ferric salts.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, sodium oxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 532-32-1: DH6650000
LD50/LC50:
CAS# 532-32-1:
Oral, mouse: LD50 = 1600 mg/kg;
Oral, rabbit: LD50 = 2 gm/kg;
Oral, rat: LD50 = 4070 mg/kg;
Carcinogenicity:
CAS# 532-32-1: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: See actual entry in RTECS for complete information.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: See actual entry in RTECS for complete information.
Other Studies: See actual entry in RTECS for complete information.
Section 12 - Ecological Information
Ecotoxicity: No data available. 96-hr. LC50; fathead minnow: GT 1,000 mg/L. 96-hr.
LC50; water flea: Gt 1,000 mg/L. 24-hr. LC50; water flea: 1.540 mg/L 24-hr. EC50
(immobilization); water flea: GT 500 mg/L 48-hr. EC50 (immobilization); water flea: GT
650 mg/L
Environmental: No information available.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
No
information
available.
Hazard Class:
UN Number:
Packing Group:
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 532-32-1 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
Canada TDG
No information
available.
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 532-32-1 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 532-32-1: 1
Canada - DSL/NDSL
CAS# 532-32-1 is listed on Canada's DSL List.
Canada - WHMIS
This product does not have a WHMIS classification.
Canadian Ingredient Disclosure List
Exposure Limits
Section 16 - Additional Information
MSDS Creation Date: 9/22/1998
Revision #3 Date: 11/08/2002
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Sodium Bicarbonate
ACC# 20970
Section 1 - Chemical Product and Company Identification
MSDS Name: Sodium Bicarbonate
Catalog Numbers: S71986, S71986-1, S78284, S78284-1, BP328-1, BP328-500,
FLS23350LC, NC9053555, NC9695834, NC9957622, S233-10, S233-3, S233-300LB,
S233-50, S233-500, S2333LC, S23350LC, S631-10, S631-3, S631-50, S631-500, S63550LC, S63712, S637212, S637212LC, S63750, XXS233225LB, XXS233PD225L
Synonyms: Baking soda; Sodium acid carbonate; Sodium hydrogen carbonate;
Monosodium carbonate; Bicarbonate of soda.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
144-55-8
Chemical Name
Sodium bicarbonate
Percent
EINECS/ELINCS
>99.7
205-633-8
Hazard Symbols: None listed.
Risk Phrases: None listed.
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: white crystals. Causes eye irritation. May cause skin and respiratory tract
irritation. Caution!
Target Organs: Eyes.
Potential Health Effects
Eye: Causes eye irritation. Causes redness and pain.
Skin: May cause skin irritation. Repeated or prolonged exposure may cause drying and
cracking of the skin.
Ingestion: May cause irritation of the digestive tract.
Inhalation: May cause respiratory tract irritation.
Chronic: Prolonged or repeated skin contact may cause irritation.
Section 4 - First Aid Measures
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the
upper and lower eyelids. Get medical aid. Do NOT allow victim to rub eyes or keep eyes
closed.
Skin: Flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash
clothing before reuse.
Ingestion: Never give anything by mouth to an unconscious person. Do NOT induce
vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Get
medical aid if irritation or symptoms occur.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or
other symptoms appear.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Material will not burn.
Extinguishing Media: Use extinguishing media most appropriate for the surrounding
fire.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Avoid generating dusty conditions. Provide ventilation. Do not get water inside
containers.
Section 7 - Handling and Storage
Handling: Use with adequate ventilation. Minimize dust generation and accumulation.
Avoid prolonged or repeated contact with skin. Avoid breathing vapors from heated
material. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid
ingestion and inhalation. Do not allow contact with water. Keep from contact with moist
air and steam.
Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area
away from incompatible substances. Store protected from moisture.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits
Chemical Name
Sodium bicarbonate
ACGIH
none listed
NIOSH
OSHA - Final PELs
none listed
none listed
OSHA Vacated PELs: Sodium bicarbonate: No OSHA Vacated PELs are listed for this
chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Crystals
Appearance: white
Odor: odorless
pH: 8.3 (0.1M solution)
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:270 deg C
Decomposition Temperature:270 deg C
Solubility: Soluble.
Specific Gravity/Density:2.16
Molecular Formula:NaHCO3
Molecular Weight:83.995
Section 10 - Stability and Reactivity
Chemical Stability: Stable in dry air, but slowly decomposes in moist air.
Conditions to Avoid: Dust generation, moisture, excess heat.
Incompatibilities with Other Materials: Moisture.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 144-55-8: VZ0950000
LD50/LC50:
CAS# 144-55-8:
Draize test, rabbit, eye: 100 mg/30S Mild;
Oral, mouse: LD50 = 3360 mg/kg;
Oral, rat: LD50 = 4220 mg/kg;
Carcinogenicity:
CAS# 144-55-8: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: Teratogenic effects have occurred in experimental animals.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: Mutagenic effects have occurred in experimental animals.
Other Studies: See actual entry in RTECS for complete information.
Section 12 - Ecological Information
Ecotoxicity: No data available. No information available.
Environmental: This chemical released into the environment is not expected to have a
significant impact.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
DOT
regulated small
quantity
provisions
apply (see
49CFR173.4)
Hazard Class:
UN Number:
Packing Group:
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 144-55-8 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
Canada TDG
No information
available.
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 144-55-8 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 144-55-8: 0
Canada - DSL/NDSL
CAS# 144-55-8 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of Not controlled..
Canadian Ingredient Disclosure List
Exposure Limits
Section 16 - Additional Information
MSDS Creation Date: 2/26/1999
Revision #3 Date: 3/18/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Sodium Chloride
ACC# 21105
Section 1 - Chemical Product and Company Identification
MSDS Name: Sodium Chloride
Catalog Numbers: S71988, S71989, S719891, S75209, S78446, S78449, S784491,
BP358-1, BP358-10, BP358-212, NC9031843, NC9107246, NC9468610, NC9607345,
NC9648474, NC9821620, NC9826699, NC9838620, NC9869539, NC9919051,
NC9974906, S271-1, S271-10, S271-10LC, S271-3, S271-350LB, S271-50, S271-500,
S271-50LC, S27125KG, S640-10, S640-10LC, S640-3, S640-350LB, S640-50, S640-500,
S641-212, S641-350LB, S641-500, S641P350LB, S641P350LLC, S642-12, S642-212,
S642-350LB, S642-500, S64212LC, S642350LBLC, S671-10, S671-10LC, S671-3, S671500, SS440-CS, WESS2713, XXS271150KG, XXS271PD250L, XXS271PD3150KG
Synonyms: Common salt; Halite; Rock salt; Saline; Salt; Sea salt; Table salt.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
7647-14-5
Chemical Name
Sodium chloride
Percent
EINECS/ELINCS
ca.100
231-598-3
Hazard Symbols: None listed.
Risk Phrases: None listed.
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless or white solid. Caution! May cause eye and skin irritation. May
cause respiratory tract irritation.
Target Organs: No data found.
Potential Health Effects
Eye: May cause eye irritation.
Skin: May cause skin irritation.
Ingestion: Ingestion of large amounts may cause gastrointestinal irritation. Ingestion of
large amounts may cause nausea and vomiting, rigidity or convulsions. Continued
exposure can produce coma, dehydration, and internal organ congestion.
Inhalation: May cause respiratory tract irritation.
Chronic: No information found.
Section 4 - First Aid Measures
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the
upper and lower eyelids. Get medical aid.
Skin: Flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash
clothing before reuse.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical
aid. Wash mouth out with water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or
other symptoms appear.
Notes to Physician: None
Section 5 - Fire Fighting Measures
General Information: Water runoff can cause environmental damage. Dike and collect
water used to fight fire. Wear appropriate protective clothing to prevent contact with skin
and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with
thermal decomposition products. Substance is noncombustible.
Extinguishing Media: For small fires, use water spray, dry chemical, carbon dioxide or
chemical foam.
Flash Point: Not applicable.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Avoid generating dusty conditions. Provide ventilation.
Section 7 - Handling and Storage
Handling: Use with adequate ventilation. Minimize dust generation and accumulation.
Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Do not ingest
or inhale.
Storage: Store in a cool, dry, well-ventilated area away from incompatible substances.
Store protected from moisture.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Good general ventilation should be sufficient to control airborne
levels. Facilities storing or utilizing this material should be equipped with an eyewash
facility and a safety shower.
Exposure Limits
Chemical Name
Sodium chloride
ACGIH
none listed
NIOSH
OSHA - Final PELs
none listed
none listed
OSHA Vacated PELs: Sodium chloride: No OSHA Vacated PELs are listed for this
chemical.
Personal Protective Equipment
Eyes: Wear safety glasses with side shields.
Skin: Wear appropriate gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: A NIOSH/MSHA approved air purifying dust or mist respirator or European
Standard EN 149.
Section 9 - Physical and Chemical Properties
Physical State: Solid
Appearance: colorless or white
Odor: odorless
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 2575 deg F
Freezing/Melting Point:1474 deg F
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:2.165
Molecular Formula:NaCl
Molecular Weight:58.43
Section 10 - Stability and Reactivity
Chemical Stability: Stable.
Conditions to Avoid: High temperatures, exposure to moist air or water.
Incompatibilities with Other Materials: Reacts with most nonnoble metals such as
iron or steel, building materials (such as cement), bromine, or trifluoride. Potentially
explosive reaction with dichloromaleic anhydride + urea. Electrolysis of mixtures with
nitrogen compounds may form explosive nitrogen trichloride.
Hazardous Decomposition Products: Toxic fumes of sodium oxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 7647-14-5: VZ4725000
LD50/LC50:
CAS# 7647-14-5:
Draize test, rabbit, eye: 100 mg Mild;
Draize test, rabbit, eye: 100 mg/24H Moderate;
Draize test, rabbit, eye: 10 mg Moderate;
Draize test, rabbit, skin: 50 mg/24H Mild;
Draize test, rabbit, skin: 500 mg/24H Mild;
Inhalation, rat: LC50 = >42 gm/m3/1H;
Oral, mouse: LD50 = 4 gm/kg;
Oral, rat: LD50 = 3000 mg/kg;
Skin, rabbit: LD50 = >10 gm/kg;
Carcinogenicity:
CAS# 7647-14-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information reported.
Teratogenicity: An experimental teratogen.
Reproductive Effects: Human reproductive effects by intraplacental route: terminates
pregnancy. Experimental reproductive effects.
Neurotoxicity: No information reported.
Mutagenicity: See actual entry in RTECS for complete information.
Other Studies: No information reported.
Section 12 - Ecological Information
Ecotoxicity: No data available. No information found.
Environmental: No information reported.
Physical: No information found
Other: No information found
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
No
information
available.
Hazard Class:
UN Number:
Packing Group:
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 7647-14-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Canada TDG
No information
available.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 7647-14-5: acute.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 7647-14-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 7647-14-5: 0
Canada - DSL/NDSL
CAS# 7647-14-5 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D2B.
Canadian Ingredient Disclosure List
Exposure Limits
Section 16 - Additional Information
MSDS Creation Date: 7/12/1999
Revision #4 Date: 3/04/2004
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Sodium hydroxide, solid
ACC# 21300
Section 1 - Chemical Product and Company Identification
MSDS Name: Sodium hydroxide, solid
Catalog Numbers: S71990, S71990-1, S71991, S71992, S71993, S71993-1, S71993-2,
S71993-3, S71993-4, S78605, BP359-212, BP359-500, M301, NC9532183, NC9994088,
NC9995368, S318-1, S318-10, S318-100, S318-3, S318-3LC, S318-5, S318-50, S318500, S318-50LC, S320-1, S320-10, S320-3, S320-50, S320-500, S392-12, S392-212,
S392-50, S392SAM1, S392SAM2, S392SAM3, S399-1, S399212, S39950, S399500,
S612-3, S612-50, S612-500LB, S6123500LB, S613-10, S613-3, S613-50, S613-500LB
Synonyms: Caustic soda; Soda lye; Sodium hydrate; Lye.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
1310-73-2
497-19-8
Chemical Name
Sodium hydroxide
Sodium carbonate anhydrous
Percent
EINECS/ELINCS
95-100
215-185-5
<3
207-838-8
Hazard Symbols: C
Risk Phrases: 35
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: white solid. Danger! Causes eye and skin burns. Hygroscopic (absorbs
moisture from the air). Causes digestive and respiratory tract burns.
Target Organs: Eyes, skin, mucous membranes.
Potential Health Effects
Eye: Causes eye burns. May cause blindness. May cause chemical conjunctivitis and
corneal damage.
Skin: Causes skin burns. May cause deep, penetrating ulcers of the skin.
Ingestion: May cause severe and permanent damage to the digestive tract. Causes
gastrointestinal tract burns. May cause perforation of the digestive tract. Causes severe
pain, nausea, vomiting, diarrhea, and shock.
Inhalation: Irritation may lead to chemical pneumonitis and pulmonary edema. Causes
severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and
possible coma. Causes chemical burns to the respiratory tract.
Chronic: Prolonged or repeated skin contact may cause dermatitis. Effects may be
delayed.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid immediately.
Skin: In case of contact, immediately flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Get medical aid immediately.
Wash clothing before reuse.
Ingestion: If swallowed, do NOT induce vomiting. Get medical aid immediately. If victim
is fully conscious, give a cupful of water. Never give anything by mouth to an
unconscious person.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use
water spray to keep fire-exposed containers cool. Use water with caution and in flooding
amounts. Contact with moisture or water may generate sufficient heat to ignite nearby
combustible materials. Contact with metals may evolve flammable hydrogen gas.
Extinguishing Media: Substance is noncombustible; use agent most appropriate to
extinguish surrounding fire. Do NOT get water inside containers.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 0; Instability: 1
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills
immediately, observing precautions in the Protective Equipment section. Avoid generating
dusty conditions. Provide ventilation. Do not get water on spilled substances or inside
containers.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Do not allow water to get into the container
because of violent reaction. Minimize dust generation and accumulation. Do not get in
eyes, on skin, or on clothing. Keep container tightly closed. Avoid ingestion and
inhalation. Discard contaminated shoes. Use only with adequate ventilation.
Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area
away from incompatible substances. Keep away from metals. Corrosives area. Keep away
from acids. Store protected from moisture. Containers must be tightly closed to prevent
the conversion of NaOH to sodium carbonate by the CO2 in air.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name
ACGIH
Sodium hydroxide
2 mg/m3 Ceiling
Sodium carbonate
anhydrous
none listed
NIOSH
OSHA - Final PELs
10 mg/m3 IDLH
2 mg/m3 TWA
none listed
none listed
OSHA Vacated PELs: Sodium hydroxide: No OSHA Vacated PELs are listed for this
chemical. Sodium carbonate anhydrous: No OSHA Vacated PELs are listed for this
chemical.
Personal Protective Equipment
Eyes: Wear chemical goggles and face shield.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Solid
Appearance: white
Odor: Odorless
pH: 14 (5% aq soln)
Vapor Pressure: 1 mm Hg @739 deg C
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 1390 deg C @ 760 mm Hg
Freezing/Melting Point:318 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:2.13 g/cm3
Molecular Formula:NaOH
Molecular Weight:40.00
Section 10 - Stability and Reactivity
Chemical Stability: Stable at room temperature in closed containers under normal
storage and handling conditions.
Conditions to Avoid: Moisture, contact with water, exposure to moist air or water,
prolonged exposure to air.
Incompatibilities with Other Materials: Water, metals, acids, aluminum, zinc, tin,
nitromethane, leather, flammable liquids, organic halogens, wool.
Hazardous Decomposition Products: Toxic fumes of sodium oxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 1310-73-2: WB4900000
CAS# 497-19-8: VZ4050000
LD50/LC50:
CAS# 1310-73-2:
Draize test, rabbit, eye: 400 ug Mild;
Draize test, rabbit, eye: 1% Severe;
Draize test, rabbit, eye: 50 ug/24H Severe;
Draize test, rabbit, eye: 1 mg/24H Severe;
Draize test, rabbit, skin: 500 mg/24H Severe;
CAS# 497-19-8:
Draize test, rabbit, eye: 100 mg/24H Moderate;
Draize test, rabbit, eye: 50 mg Severe;
Draize test, rabbit, skin: 500 mg/24H Mild;
Inhalation, mouse: LC50 = 1200 mg/m3/2H;
Inhalation, rat: LC50 = 2300 mg/m3/2H;
Oral, mouse: LD50 = 6600 mg/kg;
Oral, mouse: LD50 = 6600 mg/kg;
Oral, rat: LD50 = 4090 mg/kg;
Carcinogenicity:
CAS# 1310-73-2: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 497-19-8:
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: See actual entry in RTECS for complete information.
Section 12 - Ecological Information
No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
IATA
RID/ADR
IMO
Canada TDG
Shipping
Name:
SODIUM
HYDROXIDE,
SOLID
Hazard Class: 8
UN Number:
SODIUM
HYDROXIDE
SOLID
8
UN1823
Packing Group: II
UN1823
II
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 1310-73-2 is listed on the TSCA inventory.
CAS# 497-19-8 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 1310-73-2: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 1310-73-2: acute, reactive. CAS # 497-19-8: acute.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
CAS# 1310-73-2 is listed as a Hazardous Substance under the CWA. None of the
chemicals in this product are listed as Priority Pollutants under the CWA. None of the
chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 1310-73-2 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 497-19-8 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
C
Risk Phrases:
R 35 Causes severe burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 1310-73-2: 1
CAS# 497-19-8: 1
Canada - DSL/NDSL
CAS# 1310-73-2 is listed on Canada's DSL List.
CAS# 497-19-8 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of E.
Canadian Ingredient Disclosure List
CAS# 1310-73-2 is listed on the Canadian Ingredient Disclosure List.
CAS# 497-19-8 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 1310-73-2: OEL-AUSTRALIA:TWA 2 mg/m3 OEL-BELGIUM:STEL 2 mg/m3
OEL-DENMARK:TWA 2 mg/m3 OEL-FINLAND:TWA 2 mg/m3 OEL-FRANCE:TWA 2 mg
/m3 OEL-GERMANY:TWA 2 mg/m3 OEL-JAPAN:STEL 2 mg/m3 OEL-THE NETHERLA
NDS:TWA 2 mg/m3 OEL-THE PHILIPPINES:TWA 2 mg/m3 OEL-SWEDEN:TWA 2 mg/
m3 OEL-SWITZERLAND:TWA 2 mg/m3;STEL 4 mg/m3 OEL-THAILAND:TWA 2 mg/m3
OEL-TURKEY:TWA 2 mg/m3 OEL-UNITED KINGDOM:TWA 2 mg/m3;STEL 2 mg/m3
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW
ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 12/12/1997
Revision #6 Date: 7/14/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Sodium sulfate anhydrous
ACC# 21630
Section 1 - Chemical Product and Company Identification
MSDS Name: Sodium sulfate anhydrous
Catalog Numbers: AC196640000, AC196640010, AC196640025, AC196640050,
AC196640250, AC218750000, AC218750250, AC218755000, AC219260000,
AC219260010, AC219260025, AC354250000, AC354250010, AC424410000,
AC424410010, AC424410050, AC9597493, AC6650, AC50, S78859, S78859-1, S80193,
BP354-500, NC9084721, NC9130094, NC9146518, NC9170767, NC9581693,
NC9868791, NC9956252, S415-1, S415-10, S415-10S, S415-200LB, S415-212, S415-3,
S415-500, S415J500, S420-10, S420-3, S421-1, S421-10, S421-3, S421-300LB, S42150, S421-500, S42150LC, S429-12, S429-212, S429-250LB, S429-500, S43112,
S43412, S78859-4, SSX421PD100LB, XXACIDSSUL500, XXNASULSM200,
XXNASULSM50K, XXS41510KG, XXS41550KG, XXS41550KG2, XXS415ET2.5K,
XXS415MB200L, XXS415MN200L, XXS421PD100L, XXS429PD100LB, XXSODSULFSM1
Synonyms: Bisodium sulfate; Dibasic sodium sulfate; Disodium monosulfate; Disodium
sulfate; Sodium sulphate; Sulfuric acid, disodium salt.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
7757-82-6
Chemical Name
Sodium sulfate
Percent
EINECS/ELINCS
99
231-820-9
Hazard Symbols: None listed.
Risk Phrases: None listed.
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: white powder. Caution! This is expected to be a low hazard for usual
industrial handling. May cause eye, skin, and respiratory tract irritation. Hygroscopic
(absorbs moisture from the air).
Target Organs: No data found.
Potential Health Effects
Eye: May cause eye irritation.
Skin: May cause skin irritation.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation: May cause respiratory tract irritation.
Chronic: No information found.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid.
Skin: In case of contact, flush skin with plenty of water. Remove contaminated clothing
and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion: If swallowed, do not induce vomiting unless directed to do so by medical
personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Substance is noncombustible.
Extinguishing Media: Use extinguishing media most appropriate for the surrounding
fire.
Flash Point: Not applicable.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Avoid generating dusty conditions.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Use with adequate ventilation. Minimize dust generation and accumulation.
Avoid contact with eyes, skin, and clothing.
Storage: Store in a cool, dry place. Store protected from moisture.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits
Chemical Name
Sodium sulfate
ACGIH
none listed
NIOSH
OSHA - Final PELs
none listed
none listed
OSHA Vacated PELs: Sodium sulfate: No OSHA Vacated PELs are listed for this
chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Powder
Appearance: white
Odor: odorless
pH: 5-8 (5% solution)
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 1700 deg C (dec)
Freezing/Melting Point:880-888 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:2.68 g/cm3
Molecular Formula:Na2SO4
Molecular Weight:142.04
Section 10 - Stability and Reactivity
Chemical Stability: Stable at room temperature in closed containers under normal
storage and handling conditions. Hygroscopic: absorbs moisture or water from the air.
Conditions to Avoid: Dust generation, moisture, excess heat.
Incompatibilities with Other Materials: Aluminum.
Hazardous Decomposition Products: Oxides of sulfur, sodium oxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 7757-82-6: WE1650000
LD50/LC50:
CAS# 7757-82-6:
Oral, mouse: LD50 = 5989 mg/kg;
Carcinogenicity:
CAS# 7757-82-6: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No data available.
Teratogenicity: Oral, mouse: TDLo = 14 gm/kg (female 8-12 day(s) after conception)
Effects on Newborn - other neonatal measures or effects.; Parenteral, mouse: TDLo = 60
mg/kg (female 8 day(s) after conception) Effects on Embryo or Fetus - fetotoxicity
(except death, e.g., stunted fetus) and Specific Developmental Abnormalities musculoskeletal system.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: Tumorigenic: Subcutaneous, mouse: TDLo = 806 mg/kg/26wks (Skin and
appendage tumors).
Other Studies: See actual entry in RTECS for complete information.
Section 12 - Ecological Information
Ecotoxicity: Fish: Bluegill/Sunfish: LC50 = 12,750 ppm; 96 Hr; Static bioassayWater
flea Daphnia: LC50 = 4547 mg/L; 96 Hr; UnspecifiedFish: Fathead Minnow: LC50 =
13,500-14,000 mg/L; 24 - 96 Hr; UnspecifiedFish: Mosquito Fish: LC50 = 17,500 mg/L;
96 Hr; Unspecified This chemical is not expected to cause oxygen depletion in aquatic
systems. It has a low potential to affect aquatic organisms and is expected to have a low
potential to affect secondary waste treatment microorganisms.
Environmental: Sodium sulfate may persist indefinitely in the environment, but is not
likely to show bioaccumulation or food chain contamination effects. If diluted with water,
this chemical released directly or indirectly into the environment is not expected to have
a significant impact.
Physical: No information available.
Other: This chemical is not likely to bioconcentrate.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
Not
regulated
Hazard Class:
UN Number:
Packing Group:
Section 15 - Regulatory Information
US FEDERAL
TSCA
Canada TDG
No information
available.
CAS# 7757-82-6 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 7757-82-6 can be found on the following state right to know lists: Pennsylvania,
Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 7757-82-6: 0
Canada - DSL/NDSL
CAS# 7757-82-6 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of Not controlled..
Canadian Ingredient Disclosure List
Exposure Limits
Section 16 - Additional Information
MSDS Creation Date: 7/15/1999
Revision #4 Date: 3/30/2004
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Soft 'N Sure Skin Cleanser
Embedded Secure Document
The file Soft 'N Sure Skin Cleanser is a secure document that has been embedded in this document.
Double click the pushpin to view.
Material Safety Data Sheet
Sulfuric acid 90-98%
ACC# 22350
Section 1 - Chemical Product and Company Identification
MSDS Name: Sulfuric acid 90-98%
Catalog Numbers: AC124640000, AC124640010, AC124640025, AC124645000,
AC133610000, AC133610010, AC133610025, AC302070000, AC302070010,
AC302070025, AC424520000, AC424520025, AC424525000, S71211, S71211MF,
S71211SC, S71826, S79200, S79200MF, S79200SCMF, S80213, S80213-1, A298-212,
A300, A300-212, A300-225LB, A300-500, A300-500LC, A300-612GAL, A300-700LB,
A300C-212, A300C-212002, A300C-212003, A300C-212LC, A300C212004,
A300C212005, A300C212006, A300C212007, A300C212008, A300C212009,
A300C212010, A300J-500, A300P-500, A300S-212, A300S-212LC, A300S-500, A300SI212, A468-1, A468-2, A468-250, A468-500, A484-212, A510-212, A510-500, A510SK212, NC9008405, NC9825433, S71211SCMF, SA174-212, SA174-4, SA176-4, SA196-500
Synonyms: Hydrogen sulfate; Oil of vitriol; Vitriol brown oil; Mattling acid; Battery acid;
Sulphuric acid; Electrolyte acid; Dihydrogen sulfate; Spirit of sulfur; Chamber acid.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
7664-93-9
Chemical Name
Sulfuric acid
Percent
EINECS/ELINCS
90-98
231-639-5
Hazard Symbols: C
Risk Phrases: 35
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: clear colorless to yellow liquid. Danger! Causes eye and skin burns. Causes
digestive and respiratory tract burns. May be fatal if mist inhaled. Concentrated sulfuric
acid reacts violently with water and many other substances under certain conditions. May
cause lung damage. Hygroscopic (absorbs moisture from the air). Strong inorganic acid
mists containing sulfuric acid may cause cancer. Corrosive to metal.
Target Organs: Lungs, teeth, eyes, skin, mucous membranes.
Potential Health Effects
Eye: Causes severe eye burns. May cause irreversible eye injury. May cause blindness.
May cause permanent corneal opacification. The severity of injury depends on the
concentration of the solution and the duration of exposure.
Skin: Causes skin burns. The severity of injury depends on the concentration of the
solution and the duration of exposure.
Ingestion: May cause severe and permanent damage to the digestive tract. Causes
gastrointestinal tract burns.
Inhalation: May cause irritation of the respiratory tract with burning pain in the nose
and throat, coughing, wheezing, shortness of breath and pulmonary edema. Causes
chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm,
inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary
edema. Because its vapor pressure is negligible, it exists in the air only as a mist or
spray. Exposure may impair lung function and cause mucostasis (reduced mucous
clearance).
Chronic: Prolonged or repeated skin contact may cause dermatitis. Prolonged or
repeated inhalation may cause nosebleeds, nasal congestion, erosion of the teeth,
perforation of the nasal septum, chest pain and bronchitis. Prolonged or repeated eye
contact may cause conjunctivitis. Effects may be delayed. Workers chronically exposed to
sulfuric acid mists may show various lesions of the skin, tracheobronchitis, stomatitis,
conjunctivitis, or gastritis. Occupational exposure to strong inorganic acid mists
containing sulfuric acid is carcinogenic to humans.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid immediately.
Skin: In case of contact, immediately flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Get medical aid immediately.
Wash clothing before reuse.
Ingestion: If swallowed, do NOT induce vomiting. Get medical aid immediately. If victim
is fully conscious, give a cupful of water. Never give anything by mouth to an
unconscious person.
Inhalation: POISON material. If inhaled, get medical aid immediately. Remove victim to
fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician: Monitor arterial blood gases, chest x-ray, and pulmonary function
tests if respiratory tract irritation or respiratory depression is evident. Treat dermal
irritation or burns with standard topical therapy. Effects may be delayed. Do NOT use
sodium bicarbonate in an attempt to neutralize the acid.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use
water spray to keep fire-exposed containers cool. Substance is noncombustible. Contact
with water can cause violent liberation of heat and splattering of the material. Contact
with metals may evolve flammable hydrogen gas. Runoff from fire control or dilution
water may cause pollution. Approach fire from upwind to avoid hazardous vapors and
toxic decomposition products. Strong dehydrating agent, which may cause ignition of
finely divided materials on contact. Oxides of sulfur may be produced in fire.
Extinguishing Media: Use extinguishing media most appropriate for the surrounding
fire. Do NOT get water inside containers. If water is used, care should be taken, since it
can generate heat and cause spattering if applied directly to sulfuric acid.
Flash Point: Not applicable.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 0; Instability: 2; Special Hazard: W-
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Carefully scoop up and place into appropriate disposal container. Provide ventilation. Do
not get water inside containers. Cover with dry earth, dry sand, or other non-combustible
material followed with plastic sheet to minimize spreading and contact with water.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Do not allow water to get into the container because of violent reaction. Do
not get in eyes, on skin, or on clothing. Keep container tightly closed. Discard
contaminated shoes. Use only with adequate ventilation. Do not breathe spray or mist.
Do not use with metal spatula or other metal items. Inform laundry personnel of
contaminant's hazards.
Storage: Do not store near combustible materials. Keep container closed when not in
use. Store in a cool, dry, well-ventilated area away from incompatible substances. Do not
store near alkaline substances. Store protected from moisture. Ideally, sulfuric acid
should be stored in isolation from all other chemicals in an approved acid or corrosives
safety cabinet.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible exposure limits. Use a
corrosion-resistant ventilation system.
Exposure Limits
Chemical Name
Sulfuric acid
ACGIH
0.2 mg/m3 TWA
(thoracic particulate
mass); 3 mg/m3 STEL
NIOSH
OSHA - Final PELs
1 mg/m3 TWA 15 mg/
m3 IDLH
1 mg/m3 TWA
OSHA Vacated PELs: Sulfuric acid: 1 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear chemical goggles and face shield.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or
European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved
respirator when necessary.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: oily - clear colorless to yellow
Odor: odorless
pH: 0.3 (1N solution)
Vapor Pressure: < 0.001 mm Hg @ 20 deg C
Vapor Density: 3.38 (air=1)
Evaporation Rate:Slower than ether.
Viscosity: 21 mPas @ 25 C
Boiling Point: 290-338 deg C
Freezing/Melting Point:10 deg C
Decomposition Temperature:340 deg C
Solubility: Soluble with much heat
Specific Gravity/Density:1.84
Molecular Formula:H2SO4
Molecular Weight:98.07
Section 10 - Stability and Reactivity
Chemical Stability: Sulfuric acid reacts vigorously, violently or explosively with many
organic and inorganic chemicals and with water.
Conditions to Avoid: Excess heat, exposure to moist air or water, Note: Use great
caution in mixing with water due to heat evolution that causes explosive spattering.
Always add the acid to water, never the reverse..
Incompatibilities with Other Materials: Metals, oxidizing agents, reducing agents,
bases, acrylonitrile, chlorates, finely powdered metals, nitrates, perchlorates,
permanganates, epichlorohydrin, aniline, carbides, fulminates, picrates, organic
materials, flammable liquids.
Hazardous Decomposition Products: Oxides of sulfur.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 7664-93-9: WS5600000
LD50/LC50:
CAS# 7664-93-9:
Draize test, rabbit, eye: 250 ug Severe;
Inhalation, mouse: LC50 = 320 mg/m3/2H;
Inhalation, mouse: LC50 = 320 mg/m3;
Inhalation, rat: LC50 = 510 mg/m3/2H;
Inhalation, rat: LC50 = 510 mg/m3;
Oral, rat: LD50 = 2140 mg/kg;
Carcinogenicity:
CAS# 7664-93-9:
ACGIH: A2 - Suspected Human Carcinogen (contained in strong inorganic acid mists)
OSHA: Select carcinogen
IARC: Group 1 carcinogen
Epidemiology: No data available.
Teratogenicity: Sulfuric acid was not teratogenic in mice and rabbits, but was slightly
embryotoxic in rabbits (a minor, rare skeletal variation). The animals were exposed to 5
and 20 mg/m3 for 7 hr/day throughout pregnancy. Slight maternal toxicity was present
at the highest dose in both species.
Reproductive Effects: No data available.
Neurotoxicity: No data available.
Mutagenicity: There are no mutagenicity studies specifically of sulfuric acid. However,
there are established effects of reduced pH in mutagenicity testing, as would be caused
by sulfuric acid. These effects are an artifact of low pH and are not necessarily due to
biological effects of sulfuric acid itself.
Other Studies: No data available.
Section 12 - Ecological Information
Ecotoxicity: Fish: Bluegill/Sunfish: 49 mg/L; 48Hr; TLm (tap water @ 20C)
Fish: Bluegill/Sunfish: 24.5 ppm; 48Hr; TLm (fresh water)
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
SULFURIC
ACID
Hazard Class: 8
UN Number:
Canada TDG
SULFURIC ACID
8(9.2)
UN1830
Packing Group: II
UN1830
II
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 7664-93-9 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 7664-93-9: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
CAS# 7664-93-9: 1000 lb TPQ
SARA Codes
CAS # 7664-93-9: acute, chronic, reactive.
Section 313
This material contains Sulfuric acid (CAS# 7664-93-9, 90 98%),which is subject to the
reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
CAS# 7664-93-9 is listed as a Hazardous Substance under the CWA. None of the
chemicals in this product are listed as Priority Pollutants under the CWA. None of the
chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 7664-93-9 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
C
Risk Phrases:
R 35 Causes severe burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 30 Never add water to this product.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 7664-93-9: 2
Canada - DSL/NDSL
CAS# 7664-93-9 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D2A, D1A, E.
Canadian Ingredient Disclosure List
CAS# 7664-93-9 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 7664-93-9: OEL-ARAB Republic of Egypt:TWA 1 mg/m3 OEL-AUSTRALI
A:TWA 1 mg/m3 OEL-BELGIUM:TWA 1 mg/m3;STEL 3 mg/m3 OEL-CZECHOSLOVAKI
A:TWA 1 mg/m3;STEL 2 mg/m3 OEL-DENMARK:TWA 1 mg/m3 OEL-FINLAND:TWA 1
mg/m3;STEL 3 mg/m3;Skin OEL-FRANCE:TWA 1 mg/m3;STEL 3 mg/m3 OEL-GER
MANY:TWA 1 mg/m3 OEL-HUNGARY:STEL 1 mg/m3 OEL-JAPAN:TWA 1 mg/m3 OEL
-THE NETHERLANDS:TWA 1 mg/m3 OEL-THE PHILIPPINES:TWA 1 mg/m3 OEL-POL
AND:TWA 1 mg/m3 OEL-RUSSIA:STEL 1 mg/m3;Skin OEL-SWEDEN:TWA 1 mg/m3;
STEL 3 mg/m3 OEL-SWITZERLAND:TWA 1 mg/m3;STEL 2 mg/m3 OEL-THAILAND:T
WA 1 mg/m3 OEL-TURKEY:TWA 1 mg/m3 OEL-UNITED KINGDOM:TWA 1 mg/m3 OE
L IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEA
LAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 4/22/1999
Revision #12 Date: 9/05/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
HMIS
NFPA
2
1
Health Hazard
Fire Hazard
0
Reactivity
Personal Protective Equipment
2
1
0
See Section 15.
Section 1. Chemical Product and Company Identification
Common Name/
Trade Name
Manufacturer
Page Number: 1
Tetracaine HCl
SPECTRUM LABORATORY PRODUCTS INC.
14422 S. SAN PEDRO STREET
GARDENA, CA 90248
Catalog
Number(s).
TE128
CAS#
136-47-0
RTECS
DG490000
TSCA
TSCA 8(b) inventory: No
products were found.
CI#
Not available.
Commercial Name(s)
Tetracaine Hydrochloride
Synonym
4-Butylaminobenzoicacid-2-(dimethylamino)ethylester hydrochloride
Chemical Name
IN CASE OF EMERGENCY
Benzoic acid, 4-(Butylamino)-,2-(dimethylamino)ethylesterCHEMTREC (24hr) 800-424-9300
monohydrochloride
Chemical Family
Not available.
Chemical Formula
C15H24N2O2.HCl
Supplier
SPECTRUM LABORATORY PRODUCTS INC.
14422 S. SAN PEDRO STREET
GARDENA, CA 90248
CALL (310) 516-8000
Section 2.Composition and Information on Ingredients
Exposure Limits
CAS #
Name
1) Tetracaine HCl
Toxicological Data
on Ingredients
TWA (mg/m )
136-47-0
Tetracaine HCl:
ORAL (LD50):
3
STEL (mg/m3)
CEIL (mg/m3)
% by Weight
100
Acute: 160 mg/kg [Mouse].
Section 3. Hazards Identification
Potential Acute Health Effects Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Severe
over-exposure can result in death.
Potential Chronic Health
Effects
Slightly hazardous in case of skin contact (sensitizer).
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
The substance may be toxic to central nervous system (CNS).
Repeated or prolonged exposure to the substance can produce target organs damage. Repeated exposure to a
highly toxic material may produce general deterioration of health by an accumulation in one or many human
organs.
Continued on Next Page
Page Number: 2
Tetracaine HCl
Section 4. First Aid Measures
Eye Contact
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Get medical attention.
Skin Contact
In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove
contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get
medical attention.
Serious Skin Contact
Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate
medical attention.
Inhalation
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Serious Inhalation
Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or
waistband. Seek medical attention.
Ingestion
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical
attention immediately.
Serious Ingestion
Not available.
Section 5. Fire and Explosion Data
Flammability of the Product
May be combustible at high temperature.
Auto-Ignition Temperature
Not available.
Flash Points
Not available.
Flammable Limits
Not available.
Products of Combustion
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...).
Fire Hazards in Presence of
Various Substances
Slightly flammable to flammable in presence of heat.
Non-flammable in presence of shocks.
Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
Slightly explosive in presence of open flames and sparks.
of Various Substances
Fire Fighting Media
and Instructions
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on
Fire Hazards
Not available.
Special Remarks on Explosion Material in powder form, capable of creating a dust explosion.
Hazards
Section 6. Accidental Release Measures
Small Spill
Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Large Spill
Poisonous solid.
Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to
reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition
sources. Call for assistance on disposal.
Continued on Next Page
Page Number: 3
Tetracaine HCl
Section 7. Handling and Storage
Precautions
Keep locked up.. Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk,
evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not
breathe dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory
equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with
skin and eyes. Keep away from incompatibles such as oxidizing agents, alkalis.
Storage
Keep container tightly closed. Keep container in a cool, well-ventilated area.
Section 8. Exposure Controls/Personal Protection
Engineering Controls
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection
Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
a Large Spill
to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure Limits
Not available.
Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (Solid crystalline powder.)
Molecular Weight
300.83 g/mole
pH (1% soln/water)
Not available.
Boiling Point
Not available.
Melting Point
148°C (298.4°F)
Critical Temperature
Not available.
Specific Gravity
Not available.
Vapor Pressure
Not applicable.
Vapor Density
Not available.
Volatility
Not available.
Odor Threshold
Not available.
Water/Oil Dist. Coeff.
Not available.
Ionicity (in Water)
Not available.
Dispersion Properties
See solubility in water.
Solubility
Soluble in cold water, hot water.Miscible in water.
Section 10. Stability and Reactivity Data
Stability
The product is stable.
Instability Temperature
Not available.
Conditions of Instability
Not available.
Incompatibility with various
substances
Reactive with oxidizing agents, alkalis.
Continued on Next Page
Odor
Odorless.
Taste
Not available.
Color
White.
Page Number: 4
Tetracaine HCl
Corrosivity
Non-corrosive in presence of glass.
Special Remarks on
Reactivity
Sensitive to light.
Special Remarks on
Corrosivity
Not available.
Polymerization
Will not occur.
Section 11. Toxicological Information
Routes of Entry
Inhalation. Ingestion.
Toxicity to Animals
Acute oral toxicity (LD50): 160 mg/kg [Mouse].
Chronic Effects on Humans
May cause damage to the following organs: central nervous system (CNS).
Other Toxic Effects on
Humans
Hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Special Remarks on
Toxicity to Animals
LD50[Rat] - Route: Intraperitoneal; Dose: 23500 ug/kg
Special Remarks on
Chronic Effects on Humans
Not available.
Special Remarks on other
Toxic Effects on Humans
Acute Potential Health Effects:
Skin: May cause skin irritation. May cause sensations of heat, cold or numbness.
Eyes: Causes eye irritation. May cause sensations of heat, cold or numbness.
Inhalation: May cause respiratory tract irritation.
Ingestion: May cause gastrointestinal tract irritation with nausea and vomiting. May affect respiration (respiratory
depression) and behavior/central nervous system (central nervous system depression, muscle weakness,
euphoria, confusion,dizziness, light-headedness, twitching, tremors, drowsines, convulsions, unconciousness),
ears (tinnitus), vision (blurred vision, double vision), cardiovascular system (hypotension, myocardial depression,
bradycardia, and possibly cardiac arrest, or cardiovascular collapse).
May cause sensations of heat, cold or numbness.
Chronic Potential Health Effects:
Skin: It may be a sensitizer and cause dermatitis, an allergic reaction.
Section 12. Ecological Information
Ecotoxicity
Not available.
BOD5 and COD
Not available.
Products of Biodegradation
Possibly hazardous short term degradation products are not likely. However, long term degradation products may
arise.
Toxicity of the Products
of Biodegradation
The products of degradation are less toxic than the product itself.
Special Remarks on the
Products of Biodegradation
Not available.
Section 13. Disposal Considerations
Waste Disposal
Waste must be disposed of in accordance with federal, state and local environmental
control regulations.
Continued on Next Page
Page Number: 5
Tetracaine HCl
Section 14. Transport Information
DOT Classification
CLASS 6.1: Poisonous material.
Identification
: Toxic Solid, organic, n.o.s. (Tetracaine Hydrochloride) UNNA: 2811 PG: III
Special Provisions for
Transport
Not available.
DOT (Pictograms)
HARMFUL
STOW AWAY
FROM
FOODSTUFFS
6
Section 15. Other Regulatory Information and Pictograms
Federal and State
Regulations
No products were found.
California
Proposition 65
Warnings
Other Regulations
OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
Other Classifications
WHMIS (Canada)
DSCL (EEC)
HMIS (U.S.A.)
Health Hazard
Fire Hazard
Reactivity
Personal Protection
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
6
ADR (Europe)
(Pictograms)
Continued on Next Page
Not controlled under WHMIS (Canada).
R36/38- Irritating to eyes and skin.
2
1
0
E
S2- Keep out of the reach of children.
S46- If swallowed, seek medical advice
immediately and show this container or label.
National Fire Protection
Association (U.S.A.)
Flammability
1
Health
2
0
Reactivity
Specific hazard
Page Number: 6
Tetracaine HCl
Protective Equipment
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent.
Splash goggles.
Section 16. Other Information
MSDS Code
T3210
References
Not available.
Other Special
Considerations
Not available.
Validated by Sonia Owen on 1/20/2003.
Verified by Sonia Owen.
Printed 1/22/2003.
CALL (310) 516-8000
Notice to Reader
All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is
combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper methods
of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products, Inc. assumes
no responsibility for the completeness or accuracy of the information contained herein.
Material Safety Data Sheet
Toluene
ACC# 23590
Section 1 - Chemical Product and Company Identification
MSDS Name: Toluene
Catalog Numbers: AC167900000, AC167900010, AC167900025, AC176850000,
AC176850010, AC176850025, AC176850050, AC176855000, AC177160000,
AC177160010, AC177160025, AC177160250, AC268370000, AC268370010,
AC268370025, AC326980000, AC326980010, AC326981000, AC326982500,
AC332070000, AC332070010, AC332070025, AC364410000, AC364410010,
AC364410025, AC364411000, AC421160000, AC421160010, AC421160040,
AC421170000, AC421170040, AC421175000, AC424550000, AC424550010,
AC424550250, AC424555000, AC610110040, AC610460010, AC610461000,
AC610590190, AC610590500, AC610591150, AC610592000, AC610790190,
AC610790500, AC610791150, AC610792000, AC610951000, S80229, S80229-1,
S80229-2, S80229HPLC, T288POP19, T288POP200, T288POP50, T288RS19, T288SS19,
T288SS200, T288SS50, T290-1, T290-4, T2901LC, T290N219, T290NB219, T290POP19,
T290POP200, T290POP50, T290POPN19, T290RS19, T290RS200, T290RS28, T290SK-1,
T290SK-4, T290SS115, T290SS19, T290SS200, T290SS28, T290SS50, T291-4,
T2914LC, T291RS200, T313-4, T313SK-4, T323-20, T323-4, T324-1, T324-20, T324200, T324-4, T324-500, T324200LC, T32420LC, T324CU1300, T324FB115, T324FB19,
T324FB200, T324FB50, T324J500, T324POP19, T324POP200, T324POP50, T324POPB19,
T324POPB200, T324POPB50, T324RB115, T324RB19, T324RB200, T324RS115,
T324RS19, T324RS200, T324RS28, T324RS50, T324S-4, T324SK-4, T324SS115,
T324SS19, T324SS200, T324SS28, T324SS50, T326-P4, T326F1GAL, T326S20, T330-4
Synonyms: Methylbenzene; Methylbenzol; Phenylmethane; Toluol.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
108-88-3
Chemical Name
Toluene
Percent
EINECS/ELINCS
>99
203-625-9
Hazard Symbols: XN F
Risk Phrases: 11 20
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless liquid. Flash Point: 4 deg C. Flammable liquid and vapor.
Aspiration hazard if swallowed. Can enter lungs and cause damage. Warning! Causes
eye, skin, and respiratory tract irritation. May be absorbed through intact skin. Possible
risk of harm to the unborn child. Breathing vapors may cause drowsiness and dizziness.
May cause central nervous system depression.
Target Organs: Central nervous system, respiratory system, eyes, skin.
Potential Health Effects
Eye: Causes eye irritation. Vapors may cause eye irritation.
Skin: Causes skin irritation. May be absorbed through the skin. Repeated or prolonged
exposure may cause drying and cracking of the skin. Not expected to cause an allergic
skin reaction.
Ingestion: May cause effects similar to those for inhalation exposure. Aspiration of
material into the lungs may cause chemical pneumonitis, which may be fatal. May cause
central nervous system depression.
Inhalation: Causes respiratory tract irritation. Inhalation of high concentrations (>200
ppm) of toluene are clearly associated with CNS encephalopathy, headache, depression,
lassitude (weakness, exhaustion), impaired coordination, transient memory loss, and
impaired reaction time.
Chronic: Prolonged or repeated skin contact may cause defatting and dermatitis.
Repeated exposure in combination with constant, loud noise can produce hearing loss
and dizziness. Chronic hydrocarbon abuse (for example, sniffing glue or light
hydrocarbons such as contained in this material) has been associated with irregular heart
rhythms and potential cardiac arrest. Toluene abuse has been linked with kidney disease,
as evidenced by blood, protein, & pus in the urine, accompanied by elevated serum
creatinine, decreased urinary output, & metabolic & renal tubular acidosis. Although
kidney toxicity has not been common in cases of occupational toluene exposure, there
has been at least one report of renal toxicity following a 40-year occupational toluene
exposure. Toluene does not cause the severe injury to the bone marrow that is
characteristic of benzene poisoning. Intentional abuse of toluene vapors has been linked
to damage of the b rain, liver, kidney and to death. Repeated inhalation exposure of tolu
ene to animals causes histological changes in the brain, degeneration of the heart tissue,
and possible immune suppression.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid.
Skin: In case of contact, flush skin with plenty of water. Remove contaminated clothing
and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion: Potential for aspiration if swallowed. Get medical aid immediately. Do not
induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Causes cardiac sensitization to endogenous catelcholamines which
may lead to cardiac arrhythmias. Do NOT use adrenergic agents such as epinephrine or
pseudoepinephrine.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water
runoff can cause environmental damage. Dike and collect water used to fight fire. Use
water spray to keep fire-exposed containers cool. Water may be ineffective. Material is
lighter than water and a fire may be spread by the use of water. Flammable liquid and
vapor. Vapors are heavier than air and may travel to a source of ignition and flash back.
Vapors can spread along the ground and collect in low or confined areas. This liquid floats
on water and may travel to a source of ignition and spread fire. May accumulate static
electricity.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate
foam. Solid streams of water may be ineffective and spread material.
Flash Point: 4 deg C ( 39.20 deg F)
Autoignition Temperature: 480 deg C ( 896.00 deg F)
Explosion Limits, Lower:1.1 vol%
Upper: 7.1 vol%
NFPA Rating: (estimated) Health: 2; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Remove all sources of ignition. Provide ventilation. Use only
non-sparking tools and equipment. Control runoff and isolate discharged material for
proper disposal. Use water spray to cool and disperse vapors and protect personnel.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Ground and bond containers when transferring material. Avoid contact with
eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor),
and can be dangerous. Keep container tightly closed. Do not pressurize, cut, weld, braze,
solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only
with adequate ventilation. Keep away from heat, sparks and flame. Avoid breathing vapor
or mist.
Storage: Keep away from sources of ignition. Store in a tightly closed container. Store in
a cool, dry, well-ventilated area away from incompatible substances. Separate from
oxidizing materials.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible exposure limits.
Ventilation fans and other electrical service must be non-sparking and have an explosionproof design.
Exposure Limits
Chemical Name
Toluene
ACGIH
50 ppm TWA; skin potential for cutaneous
absorption
NIOSH
OSHA - Final PELs
100 ppm TWA; 375 mg/
m3 TWA 500 ppm IDLH
200 ppm TWA; 300
ppm Ceiling
OSHA Vacated PELs: Toluene: 100 ppm TWA; 375 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or
European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved
respirator when necessary.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: colorless
Odor: sweetish odor - pleasant odor - benzene-like
pH: Not applicable.
Vapor Pressure: 28.4 mm Hg @ 25 deg C
Vapor Density: 3.1 (Air=1)
Evaporation Rate:2.4 (Butyl acetate=1)
Viscosity: 0.59 cps @ 20 deg C
Boiling Point: 110.6 deg C
Freezing/Melting Point:-95 deg C
Decomposition Temperature:Not available.
Solubility: Insoluble.
Specific Gravity/Density:0.86 (Water=1)
Molecular Formula:C7H8
Molecular Weight:92.14
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Ignition sources, excess heat, confined spaces.
Incompatibilities with Other Materials: Strong oxidizing agents, nitric acid, sulfuric
acid.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 108-88-3: XS5250000
LD50/LC50:
CAS# 108-88-3:
Draize test, rabbit, eye: 870 ug Mild;
Draize test, rabbit, eye: 2 mg/24H Severe;
Draize test, rabbit, skin: 435 mg Mild;
Draize test, rabbit, skin: 500 mg Moderate;
Draize test, rabbit, skin: 20 mg/24H Moderate;
Inhalation, mouse: LC50 = 400 ppm/24H;
Inhalation, rat: LC50 = 49 gm/m3/4H;
Oral, rat: LD50 = 636 mg/kg;
Skin, rabbit: LD50 = 14100 uL/kg;
Carcinogenicity:
CAS# 108-88-3:
IARC: IARC Group 3 - not classifiable
Epidemiology: No information available.
Teratogenicity: In an epidemiologic study of toluene and pregnancy, occupational
exposures to toluene were said to be associated with an increased incidence of renal,
urinary, gastrointestinal, and cardiac anomalies.
Reproductive Effects: Many reports of reproductive effects of toluene abuse or heavy
occupational exposure are confounded by mixed solvent exposure or fetal alcohol
syndrome. Women exposed to toluene in lab work had a 4.7-fold increased risk of
spontaneous abortions.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: See actual entry in RTECS for complete information.
Section 12 - Ecological Information
Ecotoxicity: No data available. Bluegill LC50=17 mg/L/24H Shrimp LC50=4.3
ppm/96HFathead minnow LC50=36.2 mg/L/96HSunfish (fresh water) TLm=1180 mg/
L/96H
Environmental: From soil, substance evaporates and is microbially biodegraded. In
water, substance volatilizes and biodegrades.
Physical: Photochemically produced hydroxyl radicals degrade substance.
Other: None.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 108-88-3: waste number U220.
Section 14 - Transport Information
US DOT
Shipping
Name:
TOLUENE
Hazard Class: 3
UN Number:
UN1294
Packing Group: II
Additional
Info:
IATA
RID/ADR
IMO
Canada TDG
TOLUENE
3
UN1294
II
FLASHPOINT 4 C
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 108-88-3 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 108-88-3: Effective 10/4/82; Sunset 10/4/92
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 108-88-3: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 108-88-3: acute, flammable.
Section 313
This material contains Toluene (CAS# 108-88-3, 99%),which is subject to the reporting
requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 108-88-3 is listed as a hazardous air pollutant (HAP). This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
CAS# 108-88-3 is listed as a Hazardous Substance under the CWA. CAS# 108-88-3 is
listed as a Priority Pollutant under the Clean Water Act. CAS# 108-88-3 is listed as a
Toxic Pollutant under the Clean Water Act.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 108-88-3 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
WARNING: This product contains Toluene, a chemical known to the state of California to
cause birth defects or other reproductive harm. California No Significant Risk Level: None
of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN F
Risk Phrases:
R 11 Highly flammable.
R 20 Harmful by inhalation.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 25 Avoid contact with eyes.
S 29 Do not empty into drains.
S 33 Take precautionary measures against static
discharges.
WGK (Water Danger/Protection)
CAS# 108-88-3: 2
Canada - DSL/NDSL
CAS# 108-88-3 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2B, D2A.
Canadian Ingredient Disclosure List
CAS# 108-88-3 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 108-88-3: OEL-AUSTRALIA:TWA 100 ppm (375 mg/m3);STEL 150 ppm (5
60 mg/m3) OEL-BELGIUM:TWA 100 ppm (377 mg/m3);STEL 150 ppm (565 mg/m3
) OEL-CZECHOSLOVAKIA:TWA 200 mg/m3;STEL 1000 mg/m3 OEL-DENMARK:TWA 5
0 ppm (190 mg/m3);Skin OEL-FINLAND:TWA 100 ppm (375 mg/m3);STEL 150 p
pm;Skin OEL-FRANCE:TWA 100 ppm (375 mg/m3);STEL 150 ppm (560 mg/m3)
OEL-GERMANY:TWA 100 ppm (380 mg/m3) OEL-HUNGARY:TWA 100 mg/m3;STEL 30
0 mg/m3;Skin OEL-JAPAN:TWA 100 ppm (380 mg/m3) OEL-THE NETHERLANDS:T
WA 100 ppm (375 mg/m3);Skin OEL-THE PHILIPPINES:TWA 100 ppm (375 mg/m
3) OEL-POLAND:TWA 100 mg/m3 OEL-RUSSIA:TWA 100 ppm;STEL 50 mg/m3 OE
L-SWEDEN:TWA 50 ppm (200 mg/m3);STEL 100 ppm (400 mg/m3);Skin OEL-SWI
TZERLAND:TWA 100 ppm (380 mg/m3);STEL 500 ppm OEL-THAILAND:TWA 200 pp
m;STEL 300 ppm OEL-TURKEY:TWA 200 ppm (750 mg/m3) OEL-UNITED KINGDOM
:TWA 100 ppm (375 mg/m3);STEL 150 ppm;Skin OEL IN BULGARIA, COLOMBIA,
JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM
check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 6/01/1999
Revision #6 Date: 9/10/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Trichloroacetic Acid Solution
ACC# 40092
Section 1 - Chemical Product and Company Identification
MSDS Name: Trichloroacetic Acid Solution
Catalog Numbers: SA254 500, SA254500, SA433 500, SA433500
Synonyms: Trichloroethanoic Acid
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
7732-18-5
76-03-9
Chemical Name
Percent
EINECS/ELINCS
Water
27.0-94.
231-791-2
Trichloroacetic acid
5.4-73.0
200-927-2
Hazard Symbols: C
Risk Phrases: 35
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless liquid. Corrosive. May be harmful if swallowed. Causes eye and
skin burns. Causes digestive and respiratory tract burns. Danger!
Target Organs: None.
Potential Health Effects
Eye: Contact with eyes may cause severe irritation, and possible eye burns.
Skin: Exposure may cause irritation and possible burns.
Ingestion: May cause severe gastrointestinal tract irritation with nausea, vomiting and
possible burns.
Inhalation: May cause irritation of the respiratory tract with burning pain in the nose
and throat, coughing, wheezing, shortness of breath and pulmonary edema.
Chronic: No information found.
Section 4 - First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid immediately.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. Get medical aid
immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air
immediately. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use extinguishing media most appropriate for the surrounding
fire.
Flash Point: > 112 deg C (> 233.60 deg F)
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: Not published.
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Clean up spills immediately, observing precautions in the Protective
Equipment section. Sweep up or absorb material, then place into a suitable clean, dry,
closed container for disposal. Absorb spill with an alkaline material such as soda ash or
lime.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Use with adequate ventilation. Do not get in eyes, on skin, or on clothing.
Do not ingest or inhale. Discard contaminated shoes.
Storage: Store in a cool, dry place.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Use adequate general or local exhaust ventilation to keep
airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name
ACGIH
NIOSH
OSHA - Final PELs
Water
none listed
none listed
none listed
Trichloroacetic acid
1 ppm TWA
1 ppm TWA; 7 mg/m3
TWA
none listed
OSHA Vacated PELs: Water: No OSHA Vacated PELs are listed for this chemical.
Trichloroacetic acid: 1 ppm TWA; 7 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: colorless
Odor: weak odor
pH: Acidic
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 196 deg C
Freezing/Melting Point:54-58 deg C
Decomposition Temperature:Not available.
Solubility: Soluble in water.
Specific Gravity/Density:1.62
Molecular Formula:Cl3CCOOH
Molecular Weight:163.3648
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials.
Incompatibilities with Other Materials: Strong oxidizing agents, strong bases,
moisture.
Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, carbon
dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 7732-18-5: ZC0110000
CAS# 76-03-9: AJ7875000
LD50/LC50:
CAS# 7732-18-5:
Oral, rat: LD50 = >90 mL/kg;
CAS# 76-03-9:
Draize test, rabbit, eye: 3500 ug/5S Severe;
Draize test, rabbit, skin: 210 ug Mild;
Carcinogenicity:
CAS# 7732-18-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 76-03-9:
ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to humans
IARC: IARC Group 3 - not classifiable
Teratogenicity: Trichloroacetic acid is considered to be a developmental toxin at doses
ò330 mg/kg. Observed effects include soft tissue malformations and skeletal
malformations.
Reproductive Effects: Lowered maternal weight gain and lowered fetal weight was
observed in pregnant rats dosed with trichloroacetic acid.
Section 12 - Ecological Information
No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
Shipping
Name:
IATA
RID/ADR
IMO
TRICHLOROACETIC
ACID, SOLUTION
Hazard Class: 8
TRICHLOROACETIC
ACID SOLUTION
8
UN Number: UN2564
Packing
Group:
Canada TDG
II
UN2564
II
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 7732-18-5 is listed on the TSCA inventory.
CAS# 76-03-9 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 76-03-9: acute.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 76-03-9 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
C
Risk Phrases:
R 35 Causes severe burns.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
WGK (Water Danger/Protection)
CAS# 7732-18-5: No information available.
CAS# 76-03-9: 2
Canada - DSL/NDSL
CAS# 7732-18-5 is listed on Canada's DSL List.
CAS# 76-03-9 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of E.
Canadian Ingredient Disclosure List
CAS# 76-03-9 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 76-03-9: OEL-AUSTRALIA:TWA 1 ppm (7 mg/m3) OEL-BELGIUM:TWA 1 p
pm (6.7 mg/m3) OEL-DENMARK:TWA 1 mg/m3 OEL-FRANCE:TWA 1 ppm (5 mg/m3
) OEL-THE NETHERLANDS:TWA 1 mg/m3 OEL-RUSSIA:STEL 5 mg/m3;Skin OELSWITZERLAND:TWA 1 ppm (7 mg/m3) OEL-UNITED KINGDOM:TWA 1 ppm (5 mg/m3
) OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NE
W ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 9/30/1997
Revision #3 Date: 3/18/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Urea
ACC# 24680
Section 1 - Chemical Product and Company Identification
MSDS Name: Urea
Catalog Numbers: AC424580050, S71220, S79871, A4321285, A4321286, A4922551,
A4922553, A4922556, A4922601, A4922603, A4922605, A4922608, BP169-10, BP169212, BP169-500, BP1690LC, NC9772669, NC9915662, U0150, U0155, U15-10, U15-3,
U15-50, U15-500, U16-10, U16-3, U16-50, U16PD40KG, U16SAM1, U1712, U1721,
U17212, U17SAM1, XXU16PD190LB, XXU16PD40KG
Synonyms: Carbamide resin; Carbamimidic acid; Carbonyl diamide; Carbonyldiamine;
Isourea
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
57-13-6
Chemical Name
Urea
Percent
EINECS/ELINCS
ca. 100
200-315-5
Hazard Symbols: None listed.
Risk Phrases: None listed.
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: white crystals. Causes eye and skin irritation. Causes digestive and
respiratory tract irritation. May cause cardiac disturbances. Warning! Reproductively
active.
Target Organs: Blood, cardiovascular system.
Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation.
Ingestion: Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May
cause cardiac disturbances. May cause disturbed blood electrolyte balance.
Inhalation: Inhalation of dust causes irritation of the nose and throat, coughing and
sneezing.
Chronic: Prolonged or repeated exposure may cause adverse reproductive effects.
Laboratory experiments have resulted in mutagenic effects. Prolonged exposure or
exposure to high concentrations may cause eye damage.
Section 4 - First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes
while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively. Weak acids such as acetic
acid and propionic acid can be used as chemical antidotes, demulcents and stimulants.
Section 5 - Fire Fighting Measures
General Information: During a fire, irritating and highly toxic gases may be generated
by thermal decomposition or combustion. Wear appropriate protective clothing to prevent
contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent
contact with thermal decomposition products.
Extinguishing Media: Substance is noncombustible; use agent most appropriate to
extinguish surrounding fire. Use water spray, dry chemical, carbon dioxide, or
appropriate foam.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Avoid generating dusty conditions. Provide ventilation.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Use with adequate ventilation. Minimize dust generation and accumulation.
Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing.
Keep container tightly closed. Avoid ingestion and inhalation.
Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area
away from incompatible substances.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits
Chemical Name
Urea
ACGIH
none listed
NIOSH
OSHA - Final PELs
none listed
none listed
OSHA Vacated PELs: Urea: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Crystals
Appearance: white
Odor: ammonia-like
pH: 7.2 (10% solution)
Vapor Pressure: 1.2105 mm Hg @ 25C
Vapor Density: 2.07
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: decomposes
Freezing/Melting Point:132 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:1.335
Molecular Formula:CH4N2O
Molecular Weight:60.0408
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, dust generation, excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents, sodium hypochlorite,
sodium nitrate, calcium hypochlorite, nitrosyl perchlorate, gallium perchlorate,
diphosphorus pentachloride.
Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, irritating
and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:
CAS# 57-13-6: YR6250000
LD50/LC50:
CAS# 57-13-6:
Oral, mouse: LD50 = 11 gm/kg;
Oral, rat: LD50 = 8471 mg/kg;
Carcinogenicity:
CAS# 57-13-6: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: Oral, rat: TDLo = 821 gm/kg/1Y-C (Tumorigenic - neoplastic b y RTECS
criteria - Blood - tumors and Blood - lymphoma, in cluding Hodgkin's disease).; Oral,
mouse: TDL0 = 394 gm/kg /1Y-C (Tumorigenic - Carcinogenic by RTECS criteri a - Blood
- tumors and Blood - lymphoma, including Hodgkin's disease).
Teratogenicity: No information available.
Reproductive Effects: Intraplacental, woman: TDLo = 1400 mg/kg (female 16 week(s)
after conception) Fertility - abortion.; Intraplacental, woman: TDLo = 1600 mg/kg
(female 16 week(s) after conception) Fertility - abortion.
Neurotoxicity: No information available.
Mutagenicity: DNA Inhibition: Human, Lymphocyte = 600 mmol/L.; Cytogenetic
Analysis: Human, Leukocyte = 50 mmol/L.; DNA Damage: Mouse, Lymphocyte = 628
mmol/L.; Mutation in Mammalian Somatic Cells: Mouse, Lymphocyte = 265 mmol/L.
Other Studies: Standard Draize test: Administration onto the skin (human) = 22 mg/3D
(Intermittent) (Mild).
Section 12 - Ecological Information
Ecotoxicity: Bacteria: Phytobacterium phosphoreum: EC50 = 23914 mg/L; 5 min;
Microtox test If released to water, urea can degrade readily through biotic hydrolysis as
demonstrated by various screening studies. The presence of naturally-occurring
phytoplankton increases the degradation rate because phytoplankton use urea as a
nitrogen source and because urea is decomposed by phytoplankton photosynthesis. In
phytoplankton-rich waters, degradation occurs much faster in sunlight than in the dark.
Abiotic hydrolysis of urea occurs very slowly in relation to biotic hydrolysis.
Environmental: If released to the atmosphere, urea will degrade rapidly in the vaporphase by reaction with photochemically produced hydroxyl radicals (half-life of 9.6 hr). If
released to soil, urea is hydrolyzed to ammonium through soil urease activity (the basis
of its use as a fertilizer). The rate of hydrolysis can be fast (24 hr); however, a number a
variables (such as increasing the pellet size of the fertilizer) can decrease the degradation
rate from days to weeks.
Physical: No information found.
Other: No information found.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT
IATA
RID/ADR
IMO
Canada TDG
Shipping
Name:
No
information
available.
No information
available.
Hazard Class:
UN Number:
Packing Group:
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 57-13-6 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 57-13-6: acute.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 57-13-6 can be found on the following state right to know lists: Minnesota.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 57-13-6: 1
Canada - DSL/NDSL
CAS# 57-13-6 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D2A, D2B.
Canadian Ingredient Disclosure List
Exposure Limits
Section 16 - Additional Information
MSDS Creation Date: 5/28/1999
Revision #2 Date: 3/18/2003
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.
Material Safety Data Sheet
Xylenes, mixed isomers with ethylbenzene
ACC# 25150
Section 1 - Chemical Product and Company Identification
MSDS Name: Xylenes, mixed isomers with ethylbenzene
Catalog Numbers: AC200910000, AC327950000, AC422680000, S71223, S71232,
S71233, 23402725, S566CA, X16-4, X3F1GAL, X3FB50, X3P-1GAL, X3P1GALLC,
X3POPB50, X3RB50, X3S-20, X3S-200, X3S-4, X3SJ4, X4-20, X4-4, X5-1, X5-20, X5200, X5-4, X5-500, X5FB115, X5FB19, X5FB200, X5FB50, X5J4, X5J500, X5P-1GAL,
X5POP19, X5POP200, X5POP50, X5POPB19, X5POPB200, X5POPB50, X5RB115, X5RB200,
X5RB50, X5RS115, X5RS19, X5RS200, X5RS28, X5RS50, X5S-4, X5SK-4, X5SS115,
X5SS19, X5SS200, X5SS28, X5SS50, XYLENES
Synonyms: Dimethylbenzene; Methyltoluene.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS#
1330-20-7
100-41-4
Chemical Name
Xylenes (o-, m-, p- isomers)
Ethylbenzene
Percent
EINECS/ELINCS
96
215-535-7
Balance
202-849-4
Hazard Symbols: XN
Risk Phrases: 10 20/21 36/38
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: clear, colorless liquid. Flash Point: 21 deg C. Flammable liquid and vapor.
May cause central nervous system depression. Aspiration hazard if swallowed. Can enter
lungs and cause damage. Warning! May be harmful if absorbed through skin or if
inhaled. Causes eye, skin, and respiratory tract irritation.
Target Organs: Central nervous system, respiratory system, eyes, skin.
Potential Health Effects
Eye: Splashes of xylene in human eyes generally cause transient superficial injury. The
liquid is probably a mild irritant, based on animal information fo r mixed xylene isomers.
Skin: May be harmful if absorbed through the skin. Xylene contact causes defatting of
the skin with irritation, dryness, and cracking. Blistering may occur, particularly if
exposure to concentrated xylene is prolonged and the exposed area of skin is occluded.
Xylene liquid or vapor can be absorbed through the skin, but not as re adily as when
inhaled or ingested. Skin absorption has been reported t o be slow and significant
harmful effects are not expected by this rou te. There is one case report of a person
developing an allergic skin r eaction (contact urticaria) following exposure to xylene
(unspecified composition) vapor. The person subsequently tested positive in a patch test.
No information was provided regarding previous history of aller gies. No conclusions can
be drawn regarding the potential for xylene t o produce allergic skin reactions, based on
this single case report.
Ingestion: Aspiration hazard. May cause irritation of the digestive tract. May cause
central nervous system depression, characterized by excitement, followed by headache,
dizziness, drowsiness, and nausea. Advanced stages may cause collapse,
unconsciousness, coma and possible death due to respiratory failure. Aspiration of
material into the lungs may cause chemical pneumonitis, which may be fatal.
Inhalation: Causes respiratory tract irritation. Irritation may lead to chemical
pneumonitis and pulmonary edema. Odor thresholds ranging from 0.07 to 40 ppm have
been reported for xylenes. Inhalation overexposure may lead to central nervous system
depression, producing effects such as dizziness, headache, confusion, incoordination,
nausea, weakness, and loss of consciousness. Extreme exposures may cause other CNS
effects including death. Reversible liver and kidney damage has been reported in cases of
sever e xylene exposure. Industrial fatalities due to gross inhalation expos ure have been
described.
Chronic: Chronic exposure to xylene may cause defatting dermatitis, reversible eye
damage, dyspnea (labored breathing), confusion, dizziness, apprehension, memory loss,
headache, tremors, weakness, anorexia, nausea, ringing in the ears, irritability, thirst,
mild changes in liver function, kidney impairment, anemia, and hyperplasia, but not
destruction, of the bone marrow.
Section 4 - First Aid Measures
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical aid.
Skin: In case of contact, flush skin with plenty of water. Remove contaminated clothing
and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion: Potential for aspiration if swallowed. Get medical aid immediately. Do not
induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use
water spray to keep fire-exposed containers cool. Flammable liquid and vapor. Vapors
may form an explosive mixture with air. Vapors are heavier than air and may travel to a
source of ignition and flash back. Vapors can spread along the ground and collect in low
or confined areas. This liquid floats on water and may travel to a source of ignition and
spread fire. May accumulate static electricity.
Extinguishing Media: Water may be ineffective. This material is lighter than water and
insoluble in water. The fire could easily be spread by the use of water in an area where
the water cannot be contained. Use water spray, dry chemical, carbon dioxide, or
appropriate foam.
Flash Point: 21 deg C ( 69.80 deg F)
Autoignition Temperature: 527 deg C ( 980.60 deg F)
Explosion Limits, Lower:1.1%
Upper: 7.0%
NFPA Rating: (estimated) Health: 2; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section
8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then
place in suitable container. Remove all sources of ignition. Use a spark-proof tool. Provide
ventilation. A vapor suppressing foam may be used to reduce vapors. Water spray may
reduce vapor but may not prevent ignition in closed spaces. U.S. regulations require
reporting spills and releases to soil, water and air in excess of reportable quantities. This
material creates a fire hazard because it floats on water. If possible, try to contain
floating material.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Ground and bond containers when transferring material. Avoid contact with
eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor),
and can be dangerous. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose
empty containers to heat, sparks or open flames. Use only with adequate ventilation.
Keep away from heat, sparks and flame. Avoid breathing vapor or mist.
Storage: Keep away from sources of ignition. Keep container closed when not in use.
Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area
away from incompatible substances.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible exposure limits.
Ventilation fans and other electrical service must be non-sparking and have an explosionproof design.
Exposure Limits
Chemical Name
ACGIH
Xylenes (o-, m-, pisomers)
100 ppm TWA; 150
ppm STEL
Ethylbenzene
100 ppm TWA; 125
ppm STEL
NIOSH
OSHA - Final PELs
none listed
100 ppm TWA; 435 mg/
m3 TWA
100 ppm TWA; 435 mg/ 100 ppm TWA; 435 mg/
m3 TWA 800 ppm IDLH
m3 TWA
OSHA Vacated PELs: Xylenes (o-, m-, p- isomers): 100 ppm TWA; 435 mg/m3 TWA
Ethylbenzene: 100 ppm TWA; 435 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or
European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved
respirator when necessary.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear, colorless
Odor: aromatic odor
pH: Not applicable.
Vapor Pressure: 8.29 mm Hg @ 25 deg C
Vapor Density: 3.66 (air=1)
Evaporation Rate:0.7 (butyl acetate=1)
Viscosity: <32.6 SUS
Boiling Point: 136-140 deg C
Freezing/Melting Point:-34 deg C
Decomposition Temperature:Not available.
Solubility: Insoluble.
Specific Gravity/Density:0.865 (water=1)
Molecular Formula:C8H10
Molecular Weight:106.17
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: High temperatures, ignition sources.
Incompatibilities with Other Materials: Strong oxidizing agents, nitric acid.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 1330-20-7: ZE2100000
CAS# 100-41-4: DA0700000
LD50/LC50:
CAS# 1330-20-7:
Draize test, rabbit, eye: 87 mg Mild;
Draize test, rabbit, eye: 5 mg/24H Severe;
Draize test, rabbit, skin: 100% Moderate;
Draize test, rabbit, skin: 500 mg/24H Moderate;
Inhalation, rat: LC50 = 5000 ppm/4H;
Oral, mouse: LD50 = 2119 mg/kg;
Oral, rat: LD50 = 4300 mg/kg;
Skin, rabbit: LD50 = >1700 mg/kg;
CAS# 100-41-4:
Draize test, rabbit, eye: 500 mg Severe;
Oral, rat: LD50 = 3500 mg/kg;
Skin, rabbit: LD50 = 17800 uL/kg;
Carcinogenicity:
CAS# 1330-20-7:
IARC: IARC Group 3 - not classifiable CAS# 100-41-4:
ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to humans
OSHA: Possible Select carcinogen
IARC: Group 2B carcinogen
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: There is ample evidence that xylene produces embryotoxicity
(reduced body weight, retarded ossification, retarded kidney development, increased
extra rib) and fetotoxicity in mice and rats, but xylene is not considered teratogenic.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: No data available.
Section 12 - Ecological Information
Ecotoxicity: Fish: Rainbow trout: LC50 = 13.5 mg/L; 96 Hr; UnspecifiedFish: Goldfish:
LD50 = 13 mg/L; 24 Hr; UnspecifiedFish: Fathead Minnow: LC50 = 46 mg/L; 1 Hr; Static
bioassay Acute and long-term toxicity to fish and invertebrates: LD50 for goldfish is 13
mg/L/24 Hr.Cas#1330-20-7:LC50(96Hr.) rainbow trout = 8.05 mg/L, Static condition;
LC50(96Hr.) fathead minnow = 16.1 mg/L, flow-through conditions; LC50(96Hr.) bluegill
= 16.1 mg/L, flow-through;EC50 (48 Hr.) water flea = 3.82 mg/L, flow-through
conditions;EC50(24 Hr.) photobacterium phosphoreum = 0.0084 mg/L, Microtox test.
Environmental: In air, xylenes degrade by reacting with photochemically produced
hydroxyl radicals. In soil it will volatilize and leach into groundwater. Little
bioconcentration is expected.
Physical: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of
semivolatile organic compounds in the atmosphere, xylene, which has an experimental
vapor pressure of 7.99 mm Hg at 25 deg C, will exist solely as a vapor in the ambient
atmosphere. Vapor-phase xylene is degraded in the atmosphere by reaction with
photochemically-produced hydroxyl radicals; the atmospheric lifetime of xylene is about
14-26 hours. Ambient levels of xylene are detected in the atmosphere due to large
emissions of this compound.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as
a hazardous waste. US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous
waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 1330-20-7: waste number U239 (Ignitable waste, Toxic waste).
Section 14 - Transport Information
US DOT
IATA
RID/ADR
IMO
Canada TDG
Shipping
Name:
XYLENES
Hazard Class: 3
UN Number:
XYLENES
3
UN1307
Packing Group: II
UN1307
II
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 1330-20-7 is listed on the TSCA inventory.
CAS# 100-41-4 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 100-41-4: Effective 6/19/87; Sunset 6/19/97
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 1330-20-7: 100 lb final RQ; 45.4 kg final RQ CAS# 100-41-4: 1000 lb final RQ;
454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 1330-20-7: acute, chronic, flammable. CAS # 100-41-4: acute, chronic,
flammable.
Section 313
This material contains Xylenes (o-, m-, p- isomers) (CAS# 1330-20-7, 96%),which is
subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part
373. This chemical is not at a high enough concentration to be reportable under Section
313.
Clean Air Act:
CAS# 1330-20-7 is listed as a hazardous air pollutant (HAP). CAS# 100-41-4 is listed as
a hazardous air pollutant (HAP). This material does not contain any Class 1 Ozone
depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 1330-20-7 is listed as a Hazardous Substance under the CWA. CAS# 100-41-4 is
listed as a Hazardous Substance under the CWA. CAS# 100-41-4 is listed as a Priority
Pollutant under the Clean Water Act. CAS# 100-41-4 is listed as a Toxic Pollutant under
the Clean Water Act.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 1330-20-7 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
CAS# 100-41-4 can be found on the following state right to know lists: California, New
Jersey, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 10 Flammable.
R 20/21 Harmful by inhalation and in contact with
skin.
R 36/38 Irritating to eyes and skin.
Safety Phrases:
S 25 Avoid contact with eyes.
WGK (Water Danger/Protection)
CAS# 1330-20-7: 2
CAS# 100-41-4: 1
Canada - DSL/NDSL
CAS# 1330-20-7 is listed on Canada's DSL List.
CAS# 100-41-4 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2B, D2A.
Canadian Ingredient Disclosure List
CAS# 1330-20-7 is not listed on the Canadian Ingredient Disclosure List.
CAS# 100-41-4 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 1330-20-7: OEL-ARAB Republic of Egypt:TWA 0.5 ppm (0.9 mg/m3)
OEL-AUSTRALIA:TWA 80 ppm (330 mg/m3);STEL 150 ppm (655 mg/m3) OEL-BEL
GIUM:TWA 100 ppm (434 mg/m3);STEL 150 ppm (651 mg/m3) OEL-CZECHOSLOVA
KIA:TWA 200 mg/m3;STEL 1000 mg/m3 OEL-DENMARK:TWA 50 ppm (217 mg/m3);
Skin OEL-FINLAND:TWA 100 ppm (435 mg/m3);STEL 150 ppm;Skin OEL-FRANC
E:TWA 100 ppm (435 mg/m3);STEL 150 ppm (650 mg/m3) OEL-GERMANY:TWA 10
0 ppm (440 mg/m3) OEL-HUNGARY:TWA 100 mg/m3;STEL 300 mg/m3 OEL-JAPAN
:TWA 100 ppm (430 mg/m3) OEL-THE NETHERLANDS:TWA 100 ppm (435 mg/m3);
Skin OEL-THE PHILIPPINES:TWA 0.1 mg/m3 OEL-POLAND:TWA 100 mg/m3 OEL
-SWEDEN:TWA 50 ppm (200 mg/m3);STEL 100 ppm (450 mg/m3);Skin OEL-SWIT
ZERLAND:TWA 100 ppm (436 mg/m3);STEL 200 ppm (870 mg/m3) OEL-THAILAND
:TWA 100 ppm (435 mg/m3) OEL-TURKEY:TWA 100 ppm (435 mg/m3) OEL-UNIT
ED KINGDOM:TWA 100 ppm (435 mg/m3);STEL 150 ppm;Skin OEL IN BULGARIA,
COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPOR
E, VIETNAM check ACGI TLV
CAS# 100-41-4: OEL-AUSTRALIA:TWA 100 ppm (435 mg/m3);STEL 125 ppm (5
45 mg/m3) OEL-BELGIUM:TWA 100 ppm (434 mg/m3);STEL 125 ppm (543 mg/m3
) OEL-CZECHOSLOVAKIA:TWA 200 mg/m3;STEL 1000 mg/m3 OEL-DENMARK:TWA 5
0 ppm (217 mg/m3) OEL-FINLAND:TWA 100 ppm (435 mg/m3);STEL 150 ppm (6
55 mg/m3) OEL-FRANCE:TWA 100 ppm (435 mg/m3) OEL-GERMANY:TWA 100 ppm
(440 mg/m3);Skin OEL-HUNGARY:TWA 100 mg/m3;STEL 200 mg/m3;Skin OELJAPAN:TWA 100 ppm (430 mg/m3) OEL-THE NETHERLANDS:TWA 100 ppm (435 mg
/m3) OEL-THE PHILIPPINES:TWA 100 ppm (435 mg/m3) OEL-POLAND:TWA 100
mg/m3 OEL-RUSSIA:TWA 100 ppm;STEL 50 mg/m3 OEL-SWEDEN:TWA 50 ppm (20
0 mg/m3);STEL 100 ppm (450 mg/m3) OEL-SWITZERLAND:TWA 100 ppm (435 mg
/m3);STEL 500 ppm OEL-TURKEY:TWA 100 ppm (435 mg/m3) OEL-UNITED KING
DOM:TWA 100 ppm (435 mg/m3);STEL 125 ppm OEL IN BULGARIA, COLOMBIA, J
ORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM c
heck ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 6/22/1999
Revision #9 Date: 3/08/2004
The information above is believed to be accurate and represents the best information currently available to
us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes. In no event shall
Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,
indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been
advised of the possibility of such damages.